LOCUS       DARYVE010000001        84004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYVE010000001 DARYVE010000000
VERSION     DARYVE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..376
                     /locus_tag="TVW25_000001"
     CDS             <1..376
                     /locus_tag="TVW25_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1377686.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TVW25_000002"
                     /pseudo
     CDS             692..933
                     /locus_tag="TVW25_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TVW25_000003"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TVW25_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1377687.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TVW25_000004"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TVW25_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1377688.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TVW25_000005"
     CDS             6494..6823
                     /locus_tag="TVW25_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1377689.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TVW25_000006"
     CDS             6827..7261
                     /locus_tag="TVW25_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1377690.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TVW25_000007"
     CDS             7263..7547
                     /locus_tag="TVW25_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1377691.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TVW25_000008"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TVW25_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TVW25_000009"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TVW25_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1377692.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TVW25_000010"
     CDS             10025..10675
                     /locus_tag="TVW25_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1377693.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TVW25_000011"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TVW25_000011"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1377694.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TVW25_000012"
     CDS             12073..12813
                     /locus_tag="TVW25_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1377695.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TVW25_000013"
     CDS             12810..14528
                     /locus_tag="TVW25_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1377696.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HPKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TVW25_000014"
     CDS             14567..15655
                     /locus_tag="TVW25_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1377697.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TVW25_000015"
     CDS             15670..16374
                     /locus_tag="TVW25_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1377698.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TVW25_000016"
     CDS             16634..17122
                     /locus_tag="TVW25_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1377699.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TVW25_000017"
     CDS             complement(17632..18105)
                     /locus_tag="TVW25_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1377700.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TVW25_000018"
     CDS             18246..18926
                     /locus_tag="TVW25_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1377701.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TVW25_000019"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TVW25_000019"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1377702.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TVW25_000020"
     CDS             20440..20871
                     /locus_tag="TVW25_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1377703.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TVW25_000021"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TVW25_000021"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1377704.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TVW25_000022"
     CDS             22061..23554
                     /locus_tag="TVW25_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1377705.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TVW25_000023"
     CDS             23571..24902
                     /locus_tag="TVW25_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1377706.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TVW25_000024"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TVW25_000024"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1377707.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26090..27082
                     /locus_tag="TVW25_000025"
     CDS             26090..27082
                     /locus_tag="TVW25_000025"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEL1377708.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVARYPDLTPKERENAITKEFDAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTSESENGYHGLNGDILVWNEQLGTAFELFSMGIRVDEEALKRQVDITGDQERLQF
                     DWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL"
     gene            27254..27793
                     /gene="rsmD"
                     /locus_tag="TVW25_000026"
     CDS             27254..27793
                     /gene="rsmD"
                     /locus_tag="TVW25_000026"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1377709.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27783..28283
                     /gene="coaD"
                     /locus_tag="TVW25_000027"
     CDS             27783..28283
                     /gene="coaD"
                     /locus_tag="TVW25_000027"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1377710.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28261..29298
                     /locus_tag="TVW25_000028"
     CDS             28261..29298
                     /locus_tag="TVW25_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1377711.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29860..30474
                     /locus_tag="TVW25_000029"
     CDS             29860..30474
                     /locus_tag="TVW25_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1377712.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30478..31560
                     /gene="rlmN"
                     /locus_tag="TVW25_000030"
     CDS             30478..31560
                     /gene="rlmN"
                     /locus_tag="TVW25_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1377713.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            complement(31993..32634)
                     /locus_tag="TVW25_000031"
     CDS             complement(31993..32634)
                     /locus_tag="TVW25_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEL1377714.1"
                     /translation="MNTIFYCYCGFLVGNLFRLILNLFSEQQAKAWVKLYIGQLHLSS
                     LFFPMAKPTYNSKHEQKHWVMLPYLEIITSLIFGLAALCGLTWTQLYLLCFSLLLCFF
                     DLDSQEYPLLIWLMSFLFLLPFYSINLLTVLLLLLALLSVAFPINIGAGDFLYLANLA
                     LVVKLSSLLWIVQIASLIGILACLLLQTKKIPFIPYLTLGLIAILLFERLTGS"
     gene            32842..33372
                     /locus_tag="TVW25_000032"
     CDS             32842..33372
                     /locus_tag="TVW25_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1377715.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33745..33978
                     /locus_tag="TVW25_000033"
     CDS             33745..33978
                     /locus_tag="TVW25_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1377716.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33953..34924
                     /locus_tag="TVW25_000034"
     CDS             33953..34924
                     /locus_tag="TVW25_000034"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1377717.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34934..35314
                     /locus_tag="TVW25_000035"
     CDS             34934..35314
                     /locus_tag="TVW25_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1377718.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35710..37551
                     /gene="typA"
                     /locus_tag="TVW25_000036"
     CDS             35710..37551
                     /gene="typA"
                     /locus_tag="TVW25_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1377719.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37633..37887
                     /locus_tag="TVW25_000037"
     CDS             37633..37887
                     /locus_tag="TVW25_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1377720.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38033..39394
                     /locus_tag="TVW25_000038"
     CDS             38033..39394
                     /locus_tag="TVW25_000038"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1377721.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39391..40473
                     /locus_tag="TVW25_000039"
     CDS             39391..40473
                     /locus_tag="TVW25_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1377722.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40474..41664
                     /locus_tag="TVW25_000040"
     CDS             40474..41664
                     /locus_tag="TVW25_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1377723.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41876..43240
                     /gene="ftsA"
                     /locus_tag="TVW25_000041"
     CDS             41876..43240
                     /gene="ftsA"
                     /locus_tag="TVW25_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1377724.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43264..44592
                     /gene="ftsZ"
                     /locus_tag="TVW25_000042"
     CDS             43264..44592
                     /gene="ftsZ"
                     /locus_tag="TVW25_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1377725.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44595..45266
                     /locus_tag="TVW25_000043"
     CDS             44595..45266
                     /locus_tag="TVW25_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1377726.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45279..45941
                     /locus_tag="TVW25_000044"
     CDS             45279..45941
                     /locus_tag="TVW25_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1377727.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45946..46203
                     /locus_tag="TVW25_000045"
     CDS             45946..46203
                     /locus_tag="TVW25_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1377728.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46200..46994
                     /locus_tag="TVW25_000046"
     CDS             46200..46994
                     /locus_tag="TVW25_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1377729.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47004..47759
                     /locus_tag="TVW25_000047"
     CDS             47004..47759
                     /locus_tag="TVW25_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1377730.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48030..50828
                     /locus_tag="TVW25_000048"
     CDS             48030..50828
                     /locus_tag="TVW25_000048"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1377731.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51306..51608)
                     /locus_tag="TVW25_000049"
     CDS             complement(51306..51608)
                     /locus_tag="TVW25_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1377732.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51670..52119)
                     /locus_tag="TVW25_000050"
     CDS             complement(51670..52119)
                     /locus_tag="TVW25_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1377733.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52279..54531)
                     /locus_tag="TVW25_000051"
     CDS             complement(52279..54531)
                     /locus_tag="TVW25_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1377734.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54813..55043
                     /locus_tag="TVW25_000052"
     CDS             54813..55043
                     /locus_tag="TVW25_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1377735.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55525..56463)
                     /locus_tag="TVW25_000053"
     CDS             complement(55525..56463)
                     /locus_tag="TVW25_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1377736.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            56805..57488
                     /locus_tag="TVW25_000054"
     CDS             56805..57488
                     /locus_tag="TVW25_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1377737.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            57490..58227
                     /locus_tag="TVW25_000055"
     CDS             57490..58227
                     /locus_tag="TVW25_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1377738.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            58671..60365
                     /locus_tag="TVW25_000056"
     CDS             58671..60365
                     /locus_tag="TVW25_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1377739.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            60477..61331
                     /locus_tag="TVW25_000057"
     CDS             60477..61331
                     /locus_tag="TVW25_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1377740.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            61328..62182
                     /locus_tag="TVW25_000058"
     CDS             61328..62182
                     /locus_tag="TVW25_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1377741.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            62466..63806
                     /locus_tag="TVW25_000059"
     CDS             62466..63806
                     /locus_tag="TVW25_000059"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1377742.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            63784..63999
                     /locus_tag="TVW25_000060"
     CDS             63784..63999
                     /locus_tag="TVW25_000060"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1377743.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            63999..64868
                     /locus_tag="TVW25_000061"
     CDS             63999..64868
                     /locus_tag="TVW25_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1377744.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            64861..65688
                     /locus_tag="TVW25_000062"
     CDS             64861..65688
                     /locus_tag="TVW25_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1377745.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            65675..66145
                     /locus_tag="TVW25_000063"
     CDS             65675..66145
                     /locus_tag="TVW25_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1377746.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            66163..67824
                     /gene="recN"
                     /locus_tag="TVW25_000064"
     CDS             66163..67824
                     /gene="recN"
                     /locus_tag="TVW25_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1377747.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVIAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            68045..68917
                     /locus_tag="TVW25_000065"
     CDS             68045..68917
                     /locus_tag="TVW25_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1377748.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            69055..69906
                     /locus_tag="TVW25_000066"
     CDS             69055..69906
                     /locus_tag="TVW25_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1377749.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            69899..70741
                     /locus_tag="TVW25_000067"
     CDS             69899..70741
                     /locus_tag="TVW25_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1377750.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            70719..71306
                     /locus_tag="TVW25_000068"
     CDS             70719..71306
                     /locus_tag="TVW25_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1377751.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            71404..71679
                     /locus_tag="TVW25_000069"
     CDS             71404..71679
                     /locus_tag="TVW25_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1377752.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(71740..72444)
                     /locus_tag="TVW25_000070"
     CDS             complement(71740..72444)
                     /locus_tag="TVW25_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1377753.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(72755..73963)
                     /locus_tag="TVW25_000071"
     CDS             complement(72755..73963)
                     /locus_tag="TVW25_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1377754.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(74018..74911)
                     /locus_tag="TVW25_000072"
     CDS             complement(74018..74911)
                     /locus_tag="TVW25_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1377755.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            75280..75453
                     /locus_tag="TVW25_000073"
     CDS             75280..75453
                     /locus_tag="TVW25_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377756.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(75498..76433)
                     /locus_tag="TVW25_000074"
     CDS             complement(75498..76433)
                     /locus_tag="TVW25_000074"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1377757.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            76676..77371
                     /locus_tag="TVW25_000075"
     CDS             76676..77371
                     /locus_tag="TVW25_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1377758.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            77480..78001
                     /locus_tag="TVW25_000076"
     CDS             77480..78001
                     /locus_tag="TVW25_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1377759.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            78396..78935
                     /locus_tag="TVW25_000077"
     CDS             78396..78935
                     /locus_tag="TVW25_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377760.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            79074..79844
                     /locus_tag="TVW25_000078"
     CDS             79074..79844
                     /locus_tag="TVW25_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1377761.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            79956..82010
                     /locus_tag="TVW25_000079"
     CDS             79956..82010
                     /locus_tag="TVW25_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1377762.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            82022..82618
                     /gene="recR"
                     /locus_tag="TVW25_000080"
     CDS             82022..82618
                     /gene="recR"
                     /locus_tag="TVW25_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1377763.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            82766..83812
                     /locus_tag="TVW25_000081"
     CDS             82766..83812
                     /locus_tag="TVW25_000081"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1377764.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        23630 a        15813 c        20143 g        24418 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctgagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcacccta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
    25981 tacttttaat cggtgtataa taagcgtaat atttttttat ttttactcat gattagaatg
    26041 gtaaaaaata aaggtgactt agtcgcgaaa atgatttaaa ggaggagcta tgaaaaaaag
    26101 ctttattcat caacaagagg aaatttcctt tgttaaaaat acatttacgc agtatttgat
    26161 tgctaagctt gatgttgttg aggtgcaagg tcctatttta agtagggtcg gagacggcat
    26221 gcaggacaat ttatctgggg ttgaaaatcc ggtatctgtc catgtcttga acattcctaa
    26281 tgcaaccttt gaggtggtgc attcgctagc aaaatggaag cgtcatacct tagcacgttt
    26341 tggctttaat gaaggtgaag gtcttgtggt gaatatgaaa gcgctccgtc ctgatgaaga
    26401 ttcgctagac cagacgcatt cagtgtatgt ggaccagtgg gattgggaga aggttatccc
    26461 tgatggtcag cgcaatctag cttacctcaa agaaactgtc gaaacgattt acaaggttat
    26521 ccgcttgaca gagctagctg ttgaggcacg ctatgatatt gaagctgtct tgccaaagaa
    26581 aattaccttc attcacaccg aggagcttgt tgccagatac cctgatttga caccaaagga
    26641 gcgtgaaaat gctatcacaa aagaatttga tgcggtattt ttgattggta ttggcggtgt
    26701 attgccagat ggcaagccac atgacggtcg tgcgccagac tatgatgact ggaccagtga
    26761 gtcagaaaat ggctaccatg gcttaaatgg tgatattctc gtttggaatg agcagctagg
    26821 cacagccttt gagctattct caatgggaat tcgtgttgat gaagaggctc taaagcgtca
    26881 ggtggacatt actggagatc aggaacgcct acaatttgat tggcacaaat cgctgctaaa
    26941 tggtctgttc cccctaacca tcggtggagg aattggtcaa tcgcgtatgg ccatgttttt
    27001 gcttcgtaaa aagcacattg gagaggtcca aacatcggtg tggccacaag aggttcgcga
    27061 tacctacgac aatattttat agatgatacg gaggctaggt ttttacctat agcctctatt
    27121 tttgtcccta agtgatgctt cattagagct catttagtgc taagcaggct cgtcagttat
    27181 ataataggtc aaaaatttga aaaaatgaat catttttaag gcttgacact agatttttgt
    27241 tataatatca gttatgagaa ttgtatcagg tgaatttgga gggcgtcccc taaaaacgct
    27301 cgaaggcaag actactcgac ccacatcaga taaggtacgt ggcgcgattt ttaatatgat
    27361 tggtccttat tttaagggcg gacgtgtctt agacttgttt gctggatcag gtggcctatc
    27421 aatagaggct atttctaggg gcatgtcaga ggcagtgctg gttgagcgtg atcgtaaggc
    27481 gcaagccatt atccaagcca atattaagat gacaaaagct agccagcaat ttacgctatt
    27541 aaaaatgaac gctgagcgtg cacttgatca cttatccggt cagtttgatg tggtgttttt
    27601 ggacccacct tatgctaagg aaacgatagt agccaatata gaggccttgg tggagaaaaa
    27661 tcttttaagc gacgatgtga tgattgtttg tgagacggat cggtcggtag ctctgccaga
    27721 ggcaattgcc tggctaggga tctggaaaga aaaacaatat ggaattagca aggtaacagt
    27781 atatgtcagg taagattgga ctttatacag ggtcatttga cccagtgaca aatggacaca
    27841 tggatatgat taagcgtgct agccatttgt ttgagcatgt ttatgtcggg atttttaaca
    27901 atccaaataa gcagagcttt tttacttttg agctgcgagc tcaaatgcta agcgaagcgg
    27961 tttgtgcctt gccaaatgtg acagtggttt ctgccgagca tggtcttgca gttgacctgg
    28021 ctagggagct gtctgtgacc caccttatcc gagggcttcg caatacagct gattttgact
    28081 atgagatagg cttagagtat tttaatcata gactagcccc tgatattgag accatttacc
    28141 tgatggcgac tcatgacctg cagcccgtta gctccagtcg tatcagagag ttgattgcat
    28201 ttagagcgcc aattactggt ttggttccgc aggctgttat taatcaagtg gagaaaatga
    28261 atgaaaacaa taaaaaaaat taaatggtgg ctgattggct ttgttgcctt gctttttcta
    28321 ctgttgacac tgtttttccc cttgccttat tatattgaaa tgccaggtgg agcctatgat
    28381 attcgctcgg tattgactgt caatggcaaa gaggataagg aaaagggagc ttatcagttt
    28441 gttgtagtga gcctcagtcg ggccaccttg gctaaattgc tctatgcttg gctaacgcct
    28501 ttcactgaga ttagcaccat ggaagatact actggtggct atagcgatgc tgactacctg
    28561 cgaattaatc gcttttatat ggaaacctct caaaacagcg ctgtttatca ggcccttact
    28621 ctagcaggca aggaggtaag ctttgattat aagggtgttt atgtcttaga cgtcagcaag
    28681 gattctagct ttaaaggtgt gctgcaccta gcagatacag tgacaggtgt caatggtaaa
    28741 acatttacaa cgtctgccga tctgattgat tatgtttctc atttgacctt gggagatgag
    28801 gtgcaggtac aatttacaac cgctggtgag tcaaagactg aaaaaggaaa gattattaag
    28861 cttaaaaacg gtaaaaatgg gattggcatt accctgacag accacacaca ggtcatttct
    28921 ggtgatgagg tcgactttag cactggaggt gtgggtggac caagtgcagg cttgatgttt
    28981 actcttgata tttatgatca aatcaatcac gaagacttgc gcaagggacg tgtgattgct
    29041 ggtacaggaa ccattggcaa ggatggaaaa gttggagata ttggcggggc gggcctaaag
    29101 gtggctgccg ccgccgctgc tggtgctgat attttctttg ttccaaataa tcctgtgcat
    29161 aaggacgtca aaaaagcaaa tcctaaggct attagcaatt acgaggaggc taaaaaagca
    29221 gctaaacgac taaagacagc aatgaaaatt attcctgtga aaaccgttca agatgctata
    29281 agctacctta aaaaatagaa gcaatgcgaa gcaggctaat agggcatgct ctgtcttgct
    29341 tctagttggt ggaatttagc tagctcaaag gtcttgagac ctaagcataa ggtctagaca
    29401 gtattctaga gctagacctt atgcttgatc ctgaacaagg aagaccgcca aagaagaaca
    29461 aaatcctcag gccaaaagag cccgtaggga aatattgcca ttatctatca aggctttttg
    29521 aagaaaatca cttaaagaca gtagggcgtt aggctttact gtcttagttt ttcttgcctg
    29581 aagtcatggc tgctgatgat gttacatcaa ggcttactag ccagcagagc acaaggagca
    29641 gctttggctt aggtttattt tctctgctga ctagtaaaga aggttgctgt cagtctgctt
    29701 acaaaaacct aaaaatagtg tataataggt aggctatggg ctgtcaggag tcgctagcct
    29761 gcttacccag accagccctt tgagaagagc aagcatggct cttctcagaa taacccagga
    29821 ttaacagaca tcaaaattaa tgctaaggaa aggagctata tgaaaagaga tattttacca
    29881 gagatgtata attacaataa atttcccggt ccggaattta ttcattttga tcattatgtc
    29941 aaggctgaag gcattgagtt attgctgctg aaaaatgaaa aaaatgcttt taacacaacg
    30001 agctttggtc agcgcttcac agagatatta ttaaagtatg actatattgt tggagattgg
    30061 ggcaatgaac agctgcgtct caagggcttt tacaaggatc atcatgatgt caaaaaagct
    30121 agtcgtattt ctcgcctaga agactatatt aaagaatttt gtaactttgg ctgtgcctat
    30181 tttgttttgg aaaaccctaa tcccaaggac atgccaaaag aggaggaaag gccatcaagg
    30241 cgcaggaaat cgtctaaagc caatcgccgc agaaatcagc ctcagcatag tcagcaggca
    30301 cctgctaaag acaacttcaa aaagctaacc aaggataggt cagcggacaa gccaagcttt
    30361 accagcaaaa agcgcccagc tcctaataag accaagggaa accaaaggcg ctctcgtact
    30421 agtcaactga accataaaac ggatcacttt atcatcagaa agaaggacaa ttaatctatg
    30481 aaaccatcaa tctatggcct aacgcgcgac gagctaattg cttgggcgat tgacaatggt
    30541 caaaaggcat tcagagcgac acagatttgg gactggcttt acagaaaacg ggttcaatcc
    30601 tttgatgaaa tgactaacat ttctaaggaa tttgttgcca ttctaaagga cagcttttgt
    30661 attaatccct tgaagcagcg tgttgctcag gaatcagctg atggaacggt taagtatttg
    30721 tttgaattgc cagatggtat gctgattgaa acggttttga tgcgtcagca ctatgggcag
    30781 tcggtctgtg taactacgca ggttggctgt aatataggct gcaccttctg cgctagtggc
    30841 ttgattaaaa agcaacggga tttaaacagt ggtgaaatca ctgcacaaat tatgatggtg
    30901 caaaactatt ttgataagcg tgctcaagac gaacgtgtca gccatgttgt tgtgatgggg
    30961 attggagagc cctttgataa ttatcaaaat gtgatgacct ttcttcggac gatcaatgat
    31021 gatcatgggc ttgctattgg tgctcgtcac attactgttt caacctcagg cttggctcac
    31081 aagattcgtg aatttgccaa tgaaggagtc caagttaatc tggctgtgtc actgcatgca
    31141 cctaataatg agctgcgctc aagtatcatg aggatcaatc gttccttccc acttgataag
    31201 ctcttttcag caatcgaata ttacattgaa acaactaatc gtcgtgtgac ctttgagtat
    31261 atcatgctta ataaggttaa tgatggggta gagcaggcac aggaattggc agatttgacc
    31321 aaaaggattc gcaagctgtc ttatgttaac ctgattccct ataatcctgt ctcagagcat
    31381 gaccaataca gtagaagtcc taaggagcgt gtggcagcct tttatgacat tctaaagaaa
    31441 aatggagtga actgtgtcgt tcgtcaggag catggtacag atattgatgc tgcctgcggt
    31501 cagctgcgct ctaataccat gaaaaaggac cgacaaaaag cagcagctgc aaggacatga
    31561 tgacttggtc aaggttgctg atttgattga taggagatgg agataaaaat ctgacctcaa
    31621 ataaagcaaa caaataggtc tagttttctg agatcccgaa agcaggtctt gttcgttttt
    31681 taatgaatga gactaggtca taaagtacat gcgttaagaa tgtctaaagt gcagctcttt
    31741 ttgtcccagc ctccctcttt tatcttggta gcagttgtca agtaattgct aagcaacagt
    31801 gttttatctt tattggctgt aaaaaaagat atagtgcctt tattcacacc ttttctgaat
    31861 cacttgagcc ttgttctgac cgctcctttt ggtgcttctg atccatatag cctaagcttt
    31921 tcagagctat gaatcgaggc aaaataatag gtgttagccc tagctgcttg atgtagctag
    31981 ggcttttgtg acctagctgc cagtgagcct ttcaaatagc aatatggcta taaggcccag
    32041 tgtcagatag ggaataaaag ggattttctt agtttgtaga agtaggcagg ctagaattcc
    32101 gatcagactg gcaatttgga cgatccataa caaagagcta agcttgacca caagagcaag
    32161 attagctagg taaagaaaat ctccggcacc aatattgata ggaaaagcta cgcttagcag
    32221 tgcaagcaaa agcaatagca ctgttaacag gttaatgcta taaaatggca gcagaaacaa
    32281 aaagctcatc agccagatga gcaaaggata ctcttgactg tctaaatcaa aaaagcacag
    32341 tagcaaagag aagcatagga gataaagctg tgtccaggtc aagccgcaaa gggcagccag
    32401 tccgaaaatg aggctggtga ttatttctaa ataaggaagc ataacccagt gcttttgttc
    32461 atgcttagag ttgtaagtgg gctttgccat aggaaaaaag aggcttgaaa gatgaagttg
    32521 acctatatag agcttgaccc aagcctttgc ttgctgttca gaaaacaggt taagtattag
    32581 ccgaaagagg tttcccacaa gaaaaccaca atagcaataa aaaatagtgt tcatacttat
    32641 ttatccgaaa aacaatttaa attcttgcaa tattttaaaa aacggtgtac aatgaaacta
    32701 taaaacgaga atgattctaa ataagctgtt gatacttatc tgaattggct cgttatcgtc
    32761 gaatggagct gacaagagag tgacttttct tgctgcatac cattcatgcc cttttatatc
    32821 tatcagtaag gagagtttat tatgacaaac acactcgttg aaaacattta tgcatcagta
    32881 actcataata tttctaaaaa agaagcatca aaaaatgaaa aaaccaaggc tgttttaaat
    32941 caagcagtag cagatctatc tgtagcagct tcaattgttc atcaggttca ttggtacatg
    33001 cgtggtcctg gctttttata cctgcaccct aagatggatg agctattaga ccgcttgaac
    33061 gcgaacctag atgagatgag tgagcgcttg attactattg gtggggcacc ctactcaacc
    33121 ctagaggagt tttcacagca ttctaagcta gatgaaacaa agggaagcta tgataagtca
    33181 gtagctcagc atttagctcg tttggtagag gtttaccttt accttaccag tctttatcag
    33241 gttggtttag acattactga tgaagagggt gatgctgctt caaatgattt gttcacagca
    33301 gcaaaggctg acgctgaaaa gactatttgg atgctacagg cagagcgtgg tcaaggtcct
    33361 gctattttct aaagcgtcat acaactgata taacataaaa aaggcagagc gtggtatagc
    33421 cctgtctttt taacgccttt aaagtcagct attagtgcta gtgatgtcag gtctcacagc
    33481 ttttttatga tggatgacca acatttttag accttgtcac cacagcagag catgtggcat
    33541 ttagtccacc ttgggctcac gtcgatggtc ttacttatga tatatcaagg cttgtgacat
    33601 taccgttgcc ttttatcttc agtctgagct gctggttcct actgctgatg ctgcttgata
    33661 gtgttatagt gattttcaga aatatggaaa gcgattgcat aattgtcttg aaatctcatg
    33721 cgtaatttgc taaaatctag ttatatgaaa acattatacg atgtacagca gctgttaaaa
    33781 ggctttggta ttgttatcta catgggaaag cggctttatg atattgaaat gatgaaaata
    33841 gagctgcaaa ggctatatga tggtggcttg ttggataaac aggcttattt aactgctgag
    33901 ctgattttac gacgtgagca tcgattagag ctaaaaagag aagggcaaga aaatgagtca
    33961 aaaattgata gggattgatt tgggcggaac cacgattaaa tttggtattt taacctcaga
    34021 gggtgacgtt caggaaaaat gggcgattga gacaaatgtt ttagaggacg gtaaacatat
    34081 cgttccagat attgtcgcct cactcaagca tcgccttgac ctttatggac tgactaagga
    34141 cgattttatc ggtattggta tgggctcacc tggagctgtc aatcgcacag atcatactgt
    34201 tacaggggcc tttaacctca actggagagg cacccaagag gtgggatctg ttattgaaag
    34261 ggagctagga attccctttg ctattgataa tgacgcaaat gttgcggccc tcggcgagcg
    34321 ctgggtcggt gcaggtgaca ataatcctga tgtggtcttt atgaccttag gaacaggtgt
    34381 tggtggtggt atcatcgctg atgggaactt gattcatggt gtggctggag ctggtggtga
    34441 gattgggcac atgatagtag agccgcttaa gggctttgct tgcacctgtg gctcacaggg
    34501 ctgcctggag acagtggcct ctgctacagg tgttgttaag gttgctcgtc ttttagcaga
    34561 agcctacgaa ggagattcaa gcattaaggc agcgattgat aatggagagg ctgtctcaag
    34621 caaggacatt tttgttgcag cggaggctgg tgatgccttt gccaactctg ttgttgaaaa
    34681 ggtcagttat tatctaggac tggcagcggc taatatctca aatattttga accctgattc
    34741 ggtcgttatt ggcggtggtg tatctgctgc gggtgagttt ttacgttcac gtgttgaaaa
    34801 gtactttatg acctttacct ttccgcaggt tagacagtcc actaaaatca aaatagcaga
    34861 gcttggtaat gatgctggta ttattggtgc agctagcctt gcaagacaat ttatcacaga
    34921 ataggagtta atgatgtcac cacttacaat gattggctgg gtattgcttg cgggagtgat
    34981 tgcctattac ctttggaatt atgtttccta tagaagaatg gcaaagcagg ttgataatga
    35041 tacctttaag gagctgatgc gtcaggggca agtgattgac ctgcgcgatc cagcttcctt
    35101 tagggcaagg catatcctag gcgctagaaa ttttcctgcc cagcagttta ctacctctat
    35161 taaggctttg agaaaggaca agccaatctt gctttatgaa aatgtaagac ctcaatatcg
    35221 ggtcaaagca gtcaaaacat tacgtaaggc tggctatacg gacctttatg tcctaaaagc
    35281 gggactagat tattggaatg gtaaggttaa atagccttat agtccttttt gctgagctaa
    35341 cgtttgctgc tatgtgtcgg aacgttgcaa gcagcagctt atctaagctt gtcatgctag
    35401 tttcacagcc caaagtggct ggccgtataa acgcagctgc ttttagatgc cggtaggagc
    35461 ttttgtcagc ttctttaggg attgttttaa gtgatgtaga gaggccgttc tgagagaaag
    35521 ccttgtagtt agaaaaagag atgagaaagc taaggctctt gctgctgttg taagagttag
    35581 ctttcttttt cttttttgtg tggcgcattt aagggcttga aaacatttac aattccctca
    35641 gatcggtttt ttaaaaaaat ttgtgttata ctgttttagt taaaactatt tatgctacaa
    35701 gaggaaaaaa tgacaaaatt tagagaagat attcgtaacg ttgctattat tgcccacgtt
    35761 gaccatggga aaacaacgct cgttgatgaa ttactaaagc aatcccatac actagatgag
    35821 cgcaaagagc ttcaagaacg tgcgatggat tcaaatgacc ttgaaaaaga gcgtggtatt
    35881 accattcttg ctaaaaatac cgcagtagct tataacgatg ttcgtattaa tatcatggat
    35941 actcctgggc acgctgactt tggaggcgag gttgagcgta tcatgaaaat ggttgatggt
    36001 gttgtccttg ttgttgacgc ttacgaggga accatgcctc aaacacgctt tgtgctgaag
    36061 aaggccttag aacaaaattt aaccccaatc gttgtggtta ataagattga taagccatca
    36121 gctcgtccag ctgaggttgt tgatgaggtt cttgagcttt tcattgagct tggtgcagac
    36181 gatgatcagc tggagttccc tgttgtttac gcttcggcga tcaatggcac atcttcgttg
    36241 tcagatgatc ctgctgatca ggaaaaaaca atggctccga tttttgatac cattatcgat
    36301 catattccag cacctgttga taactcagct gagccccttc aattccaggt gtcacttctt
    36361 gattacaatg attttgtagg tcgtattggg atcggtcgtg tctttcgtgg gactgttaag
    36421 gttggagatc aggtgacgct ttcaaagctt gatggcacca ctaaaaattt ccgcgttact
    36481 aagctgtttg gcttcttcgg gcttgagcgc aaggagattc aagaggccaa ggctggtgac
    36541 ttgattgcag tttctggtat ggaggacatt ttcgttggtg agacgattac accaacggat
    36601 tgtgtggagg ctttgcctgt tcttcgcatt gatgagccga cacttcaaat gaccttcttg
    36661 gttaacaact ctccctttgc tggtcgtgaa ggcaaatggg taacctctcg taaggttgag
    36721 gagcgtttgc ttgtggagct tcaaacagat gtgtcccttc gtgttgagcc aacagaatca
    36781 ccagataaat ggattgtgtc aggtcgtggt gagctgcatc tatctatttt aattgagacc
    36841 atgcgtcgtg agggctatga gcttcaggta tcgcgtccag aggttatcat taaggaaatt
    36901 gatggtgtca agtgtgagcc ttttgaacgt gtacagattg acacaccaga ggaatatcaa
    36961 ggtgctatta tccaatcctt gtcagaacgt aagggggata tgcttgatat gcagatggtt
    37021 ggtaatggtc aaacgcgtct tatttttctc attcctgccc gcggcttgat tggttattcg
    37081 actgaatttt tatcaatgac acgtggctat ggtatcatga atcatacctt tgatcagtat
    37141 ctgccagtgg ttgctggtga gattggtgga cgccatcgtg gagcgctggt ttcgattgaa
    37201 aacggtaagg caacaaccta ctcaatcatg cgtattgaag agcgcggaac aatctttgtt
    37261 aacccaggaa ctgaggttta tgagggcatg attgttggtg aaaattctcg tgacaatgac
    37321 cttggggtta atatcacaac tgctaagcag atgaccaacg ttcgttcagc aacaaaggat
    37381 cagacagctg ttatcaaaac accacgtatt ctaacccttg aggaatctct tgaattcttg
    37441 aatgatgacg aatacatgga ggtaacgcca gaatcaatcc gcttgcgcaa gcaaattttg
    37501 aacaaagcag cgcgtgataa agctaataaa aagaaaaaat cagcagaata aaggctggtt
    37561 ggtctgagca tcacactccc ttgccgcttt aactagtaag ctaggttggc agaggattga
    37621 aaggagcttt ctgtgtttta tcttattatt gcagccttga ttacctctta ttacctgttt
    37681 atggcaccaa agagcgtccg taacacacta ggtatgattg gtttggttgg tttggttgcc
    37741 ctattgattg tgctagctgg cttaagtttt atcaaaatca tgcaaacgcc caaggaaatt
    37801 ttcgttggtc tagccatgat agtattgggc tactatgccc taagggacat tcaaaaaatc
    37861 cctaaaaaac caaagagtaa acattagcat caagcattga gtcaaatctt aatagggttt
    37921 gactttttct gtctttgtac tggccttatg cgctgctatc tgtaaaatct tgaaaaagca
    37981 gttaaataag ggtaaaatag tagtcaaata gacatagata gtgtggataa aaatgaagac
    38041 aataacggaa ttccaaaata aaaaggtatt gattcttggc ctggccaaat cgggcgaagc
    38101 agcagctagg cttttagccc ggttgggagc tattgtgaca gttaatgata gcaagccctt
    38161 tgaggaaaat cccgcagcac aggctcttct tgaggagggc ataagggtta tttgtggtag
    38221 ccaccccttg gagctgttag atgaagactt ttattgtatg gttaaaaacc cagggattcg
    38281 ctatgacaac ccgatggtgg tacgcgcctt agataaggct atttctattc taacagaggt
    38341 tgagctggct tatttggtat ctgaagcacc tatcattggt attacgggct caaatggtaa
    38401 aaccactaca accacaatga ttgctgatgt gctaaatgct gggaaccatt cagctctttt
    38461 ggctgggaat atcggctttc ctgcttcaga ggtggctcaa gctgctacag caaaggatat
    38521 actggtcatg gaattgtctt cctttcagct gctggggact gagcagtttc agccacatat
    38581 tgcagtcatt actaacctag tgcctactca tcttgattat catgggagtt ttgaggacta
    38641 tatagcggcc aagtggcgca ttcaacatcg aatgaccgat aaggattacc ttgtgttaaa
    38701 tgctgatcaa gagctggtaa aatcattggc tcaaaagact aaagcaagtc ctgtcttttt
    38761 ttctaccaaa gaaaaagttg atggtgctta tttggcagat gggtatcttt atttcaaaga
    38821 ggagaggctg atgtcagcag ctgagcttgg tgttcctgga aggcataaca ttgaaaatgc
    38881 tcttgccacc attgctgttg caaagctaag aggcatttct aatcaagtga tatcaaggac
    38941 tttgtctcac tttagggggg tgaagcaccg ccttcagtta gttggtacat tgaatcaagt
    39001 gaccttctac aatgacagca agtcaaccaa tatcttggct tgtcaaaaag ccttgtcggg
    39061 ctttgataat agcaaggtta tcctgattgc tggtggcttg gatcgtggca atgaatttga
    39121 tgagctggtg ccagacctcg ttggtcttaa aaagatgatt cttttagggg aatccgcaga
    39181 gcgtatgaag cgagctgcag acaaggcagg agtgtcctat cttgatgcca aagatgttgc
    39241 agctgccact aaaatagcct ttgagcaggc aaaggctggt gatattatct tgctgagccc
    39301 agccaatgct agctgggata tgtatccaag ctttgaaagc cgcggcgacg agtttttagc
    39361 agcctatgac gcgttaaaag gagaggctca atgaccaaga aaatcatttt taccggtggt
    39421 ggaacagctg gtcatgtcac tttaaacctt atcctcatac cgaagtttat caaagatggc
    39481 tgggaggttc actatattgg tgatgacaaa ggcattgagc atcaggagat caaaaagtca
    39541 ggtcttgatg tcacctttca tgctattgca actggaaaat taaggcgtta tttctcttgg
    39601 caaaacctgc ttgatatctt caaggtaggc tttggtgtca tgcaatcact ttttatcata
    39661 gctagactaa ggcctaaggc tctcttttca aagggaggct ttgtgtcggt tcctcctgtg
    39721 attgctgcaa ggcttttagg ggtgccggcc tttattcatg agtcggatct ttctatgggc
    39781 ttggctaata ggattgctta tcggtttgca acaacgatgt atacaacctt tgagcaagag
    39841 cagacactgg caaagctcaa gcatgttgga gcggttacca aggtgacagg tcctgggagt
    39901 cgatcggtga cttctaagca gcttgaagct gttttggagt attttgatcc taatttaaaa
    39961 acacttttgt ttattggagg ctccgcaggg gctagggtgt ttaaccgctt tatcactgac
    40021 catcctgagc taaaggaaga ctttaatatc atcaatatct ctggcgatcc tagcctaaat
    40081 gagcttagtt ggcatcttta ccgcgtggat tatgtgactg atctgtatca accgctcatg
    40141 gaaatggctg atctggtagt gactcgcgga ggctctaaca cactttttga attattagcg
    40201 atgagaaagc tccagcttat tatcccactt ggcaaagagg ccagtcgagg tgatcagctt
    40261 gagaatgctc attattttac aacaaggggc tatgctgagc aattattgga gcaggaattg
    40321 accctgcctc attttcaaga gaaagtgaga gaagtctttg ctaagcaatc ggactattta
    40381 tctgcaatga agagctctag cgagctccaa tcaccagaaa gcttttacca gcttttaagt
    40441 gccgacatta gctccgcgac aaaggaaaat taaatggcag ataagacaaa acattcagaa
    40501 gaaaaagccg ctttgaccga atggcaaaag cgtaatattg aatttctcaa caagaagcag
    40561 cagcaggctg agaaagacaa aaaactaaaa gaaaaattat taaatgagaa aatagcgcaa
    40621 gctcagggag aggcagcttc aaaggctgac caagaagata cagatgaagc tgaggagaaa
    40681 actgaggtaa gccaagcggg tactgatgag ggtgagccgc tgccagaagc atcagagcag
    40741 gaagtcccct ccccaaaaga caagccatta aaagtcccca aagaaaaaag tccaaagcag
    40801 caggcacttc aaaagggctg gcctgtattg ctggtgtcgt ttgtggtttt gtgcctgtcg
    40861 atttttatga tcacacccta tagtaaggtc aaggatttct ccgtcaaggg caataaaaaa
    40921 acaagcgttg aggacttagt tagagacagt gggatcaagt catctgatta ctggattact
    40981 ctattagcct ctccgggttc ttatgaaaat gcggttttaa aagccaatcc ctgggtgaaa
    41041 aaggtggctt tgcgttacgg ctttcccaat catttccgct ttgatgtgac agagtttgat
    41101 attattgcct acgctcaggt agctgaaggg tttcaactga tcctagaaaa tggcaagcga
    41161 gttgctgctg tcaagcaggc tgctttgcct aaatcctttt tgattttaaa tcttgagcat
    41221 gaaaaagaga ttcaagatgt cattaatcgc ttgaccaaaa tcccaagtga cctagtcaag
    41281 gctatcaaat cagtgtcatc ggccaattca cagacaacta aggatttgct gcttcttgaa
    41341 atgcacgatg gcaaccttat cagggtacct cggtcacagc ttgagctaaa gctgccttat
    41401 taccaaaaaa tcaagaagaa tcttgatact gctagcattg ttgatatgga ggttggtatc
    41461 tatacgacca ctgctgaaat tgaaaacatg cctgaggtgc cagcgtctgc tcaagcttct
    41521 caggcagata agcctgctga ggcttcacca gagcagggtg aagagcaggc cacacaggag
    41581 cagcctagcc ctgaaacacc tgctaatcct gaggccacaa atccctcagt cgcccagcct
    41641 actgagcagg caaatcaaca gtaatcgttt agggtaagag aagggggcaa aaaagcattt
    41701 aaggctctta aattaggccc ttgttgaacg gcaaaaaaac attaagttta tataacaaaa
    41761 aacgtaaaat ggtaacattt tacgtttttt tatgatataa tattccctga ataattctgc
    41821 tttttagcag tgtttttgaa tagtaaaagt ttggaaagta agtgaggtcg agtgaatggc
    41881 tagaaatggc ttttttactg gtttggacat tggaacaagc tcgataaagg ttttggtagc
    41941 agagtttatc tctggcgaga tgaatgttat tggtgtgagc aatgttccga gtactggcgt
    42001 aaaagatggc ataatcattg atatagaggc agcagccgct gctattaaaa ctgcagtaga
    42061 acaagctgaa gaaaaagcag gaatgacaat tgaaagggtc aatgttgggc tgccagcaaa
    42121 cctccttcaa attgagccga cacaaggcat gattcctgtt cctagcgaat caaaagaaat
    42181 caaagatgaa gacgttgata gcgttgttaa gtcagcacta actaagagca ttactccaga
    42241 gcgagaggtg atttccttag tccctgaaga gtttattgta gacggctttc agggcattcg
    42301 agatcctcgt ggcatgatgg ggatcaggct tgaaatgcgc ggtctgattt acactggacc
    42361 aagcacaatc ctgcataact taagaaagac agttgagcgt gctgggatta aggttgaaaa
    42421 catcatcatt tctcctttgg caatggctaa ggcggtgtta aatgaaggtg aacgtgaatt
    42481 tggtgctacg gtcattgaca tgggtggagg acaaaccacc gttgcctcaa tgcgagcaca
    42541 ggaattgcag tacaccaata tctatgcaga gggtggcgag tatatcacaa aggatatctc
    42601 taaggttctt aaaacgtcaa tgtcaattgc agaggccttg aagtacaatt ttgggcaggc
    42661 tgatatggca gaggcaagct tgactgacac tgttaaggtt gatgttgttg gcagtgatga
    42721 gccagttgag gtaacagagc gttacttatc agagattatc tcggctcgtg ttcgccatat
    42781 tctagatcgt gttaagcagg atttagaaag aggacgcctg cttgatttac ctggtggcat
    42841 tgtgctgata ggtggcggcg ccattatgcc gggcgtggtt gaggttgctc aagagatttt
    42901 tggaaccaat gttaagcttc atattccaaa tcaggttggt attcgtaacc caatgtttgc
    42961 caatgtcatt agcttggtcg agtacgttgg tatgatgtca gaggtggacg ttttagcgca
    43021 aaatgctgta tcaggcgagg aattgctaag acgtaagccg atcgacttta ctggccaaga
    43081 agcttacttg ccagactaca atgagactag gggatttgaa ccggctccta attatgagca
    43141 gcaagtgccc caagcagact acgagcctca agaacccgct gaaccaaagc aaaagatttc
    43201 agagcgtgtt cgtggcattt ttggaagtat gtttgattaa aagtaataaa gtgaggaaat
    43261 aaaatggcat tttcatttga tacggcatcc attcaaggtg caatcattaa ggtaatcggt
    43321 gttggtggag gtggcggaaa cgctattaac cgcatgattg atgagggggt tgcaggtgtt
    43381 gagtttatcg ctgcaaacac tgatattcag gcattaagct catcaaaagc agaaacagtt
    43441 gttcagcttg gtcctaaatt aactcgtggt cttggtgctg gaggtcagcc agaggttggt
    43501 cgtaaggcag cagaggaaag cgaagaggtt ctcacagaag ctttgactgg cgctgatatg
    43561 gtctttatca ctgctggtat gggtggaggc tctggaacag gagcagctcc agtgattgct
    43621 cgtatcgcta agagcctagg agccttgact gtggcagttg taacacgtcc atttggcttt
    43681 gaaggcaaca aacgcagtaa ttttgccatt gaggggattc aggagctaag agagcaggtt
    43741 gataccttat tgatcatctc aaataataac ctgcttgaaa ttgttgacaa aaagacacca
    43801 ttgcttgaag cgcttagcga agcagacaat gttttgcgtc agggtgtaca agggattact
    43861 gatctgatta caagccctgg cttgattaat cttgactttg ccgatgttaa gactgtgatg
    43921 gcaaataaag gcaatgcact tatggggatc ggtattggtt ctggtgagga acgtattgta
    43981 gaggcagctc gtaaggctat ctactcacca ttacttgaaa caacaattga cggtgctgaa
    44041 gatgttatcg ttaacgtgac aggtggactt gatatgaccc tcacagaggc tgaggaggca
    44101 tctgaaattg ttggtcaggc agcaggtcaa ggcgttaaca tctggctagg aacatcgatt
    44161 gatgactcta tgagagacga aattcgcgta acagttgttg caacaggtgt tcgtcaggat
    44221 aaggcggagc aagcctcagg atttcgtcag ccacgcacct acactcagtc taacgctcag
    44281 caggctgctg gagcacaata tgcttcagag caggtgagac agactgcgca gccaagcttt
    44341 gatcgtcgtt catcaagctt tgattttgat atgggtgaaa cacgtgagat gcctaagtct
    44401 cagcaagcta tgccagctca tggccacaat cataatcagg gctcagcttt tggaaattgg
    44461 gacttacgtc gagacaatat tgctcgtcca gcagaaggtg agcttgacaa tcaattgaac
    44521 atgtcaacct tctcatcaaa tgatgacatt gatgatgaat tagaaacacc accatttttc
    44581 aaaaatcgtt aatgatggat ttacaaaaaa ataaggatat tgtttttgaa aatattcgct
    44641 tagccactca ggcagccaac cggcctgaaa acagtgtgtc agttatcgct gtcacaaaat
    44701 atgtggacaa ggcagttgca ggtcagctga ttgatatggg gattgagcat atcgctgaga
    44761 accgtattga taagtttcta gataaatatg aagccttgaa agataggcaa gttacttggc
    44821 attttatcgg tactttacag cgtcgaaagg taaaggaagt gattaataag gttgattatt
    44881 ttcatgcctt agattcagta aaactggctt tagaaattga aaagagagct gaccaccctg
    44941 tgaagtgttt tctacaagtt aatatttctg aagaagaaag caagcatggt tttaagattg
    45001 ctgagcttga tgctgctatt gaggaaatca gcaagatgga aaagcttcat cttgtcggta
    45061 tcatgacaat ggcacctatt gatgccagtc agcaagagct tagaagcatt ttccaaaaag
    45121 caaatcaatt aagaaaaaac ttgcagtcaa aaaagagaaa gaatatgccg tttacagaat
    45181 tgagtatggg catgagtaac gattatccaa ttgctattca agaaggctca acctttgttc
    45241 gtattggaac atctttcttt cactaaatgg agaataagat ggcaattaaa gacgcattta
    45301 ataagatgat ttcttatttt gatactgatg gggtcagtga agtagaagag gagctatcct
    45361 ctaaaaagca agaagagcct gtgactaaat cacaacagac cagcagacct aatcagcagc
    45421 aacaagcagc tagagcgagt cagccccagc agcctaagca ggctagacct cagatgcaag
    45481 ctcagcaaag accacaatca caatcaagag ctgcctatgc tgagcgacca tatcaaggtc
    45541 aaagtcaagc acgtgtttct catgactaca atgacagaag ggcgacgtca gccccgtctg
    45601 cttctagtcg tcgtgagcaa tatcagcatg ctgctcatca agagcaaaca actattgcct
    45661 tgaagtatcc tcgtaagtat gaggacgccc aagaaattgt tgatcttttg attgttaatg
    45721 agtgtgtgct gatcgatttt caatacatgc tagatgctca ggcaaggcgt tgcctagatt
    45781 ttattgacgg tgctagtaag gtattgtatg gtactctgca aagggttggt tcttccatgt
    45841 atctgttgac cccatcaaat gtatctgtta atattgaaga gatgaatatc ccaaataatg
    45901 gccaagatat tggttttgat tttgatatga agagacgcta gtgtgatgat ttttatactg
    45961 ttgatacttc taaagctaat taaggtttat tcctatttgc tgctagtcta tgccttactg
    46021 tcttggtttc ctggagccta cgactcttgg cttggcaggc tggtcagcga tatagtagag
    46081 cctatcttaa aaccctttag atcattgaac ctacagtttg cgggcttgga ctttactatt
    46141 tacctagtga tgattggtct aaatgtttta agtgagatct tgataagagt gttgatctca
    46201 tgactgttca aacaatgctt tatcagcatt ttcagcctga tgaacaccca tttattgaaa
    46261 gaatgcttga cttgatcgct cgtgttgagg ctaattattt attagaggtt actgattttt
    46321 taaatccgcg agaggtcacg attttaaaag gcttagtcgc agcaaccaat ctgcagtgct
    46381 ttagctctac tgattattat cctagtgaat atggtcgtgt gattgttgct cctgactatt
    46441 attgtctaga taaggcagat tttgacttgg ctttgattga ggtgacctat aatgctaagt
    46501 ttaatcagct gacacatgca cagattttag gcaccttaat taatgaattg ggaatcaaaa
    46561 gagccttact tggcgatatt tttgttgaga taggtcatgc tcaggtcatg attaatcgac
    46621 agctgttaag ctattgttta ggaacgattg ctaaaatagc aaaagctagg gtcaagctca
    46681 aagaaattga tcttgatcag ctgttaaatc tgacagctaa tcagcaggtt ctgactgata
    46741 taatggtatc tagtctacgc gttgatcgct tgattgctac cgtattaaag caatctagaa
    46801 atcaggcgat aaggcttgtt gaagcaggca aggtcaaggt taactatcag cttgtcacta
    46861 aagcctctca gcctgtagct gttggtgatt taatcagcat tcgtggctac ggtaggttta
    46921 gcatactaac agacaatggc ttcacaaaaa atgggaaata taagctaaca cttagcaaaa
    46981 tgatgcgtaa ataaggagat ataatggcac ttacagcact agaaattaaa gataaaacgt
    47041 ttaagacaaa gtttcgtggc tacagtgaag aggaagtaaa tgaatttctt gagattgttg
    47101 tagacgatta tgaggctttg gttcgcaaaa atcgtgataa tgaagctaag ataagagagc
    47161 ttgaagaaaa gctgtcttac tttgatgaga tgaaggaatc attgagtcaa tctgttatcc
    47221 tagcccagga aacagctgaa aaagtgaaat cctcagcaaa tgctgaagca accaatttgg
    47281 tcagcaaggc aacctatgat gctcagcatt tacttgatga gtcaaaagca aaggctaacc
    47341 aactgttgcg cgacgcaaca gatgaagcaa agcgcgttgc tattgagaca gaggaattaa
    47401 agcgccagac acgcgttttc catcagcgct tggtttcagc tattgagtca cagctaagct
    47461 tatccaattc gcctgagtgg gacgaattgt tgcagccaac agctgtctac cttcaaaact
    47521 ctgatgcagc ctttaaagag gtggttaaaa ctgtccttaa tgaagatatt cctgaggctg
    47581 atgacagcaa ttcctttgat gcaacacgtc agtttacacc agaggagcta gaggagctgc
    47641 agcgtcgtgt tgaagaaagc aataaggagc tagaagccta tcaggtgcag cgagaagagc
    47701 aagctagcga gcctgaagtg aacctaagcg agacacagac ctttaaattg aatatttaat
    47761 cataagaaaa acaggattga atgcccaaaa tcacagcaag taggagatga tgagagtcct
    47821 atattccctg agcatgacaa ttatcatttt cttcaatcat cactgaatga cagtaagtga
    47881 cgagggaggc tcaccttacg agcaaagagg gaacagcaaa agggatttta ctgttctgaa
    47941 ttaaggtggt accacgagct ttcgtccttt ttgagacggg gctttttttg taattctgat
    48001 aagatattga ctaaaaggag tttgacaaga tgaaattaaa agaaacactt aacttaggca
    48061 aaacggcctt tccaatgcgt gccggtctac ccaacaagga gccacaatgg caaaaggctt
    48121 gggacgaggc tgagatttac aaaaaacgtc aagccttaaa tgaaggcaag cctgcctttc
    48181 acctgcacga tgggcctccc tatgcaaatg gtaatatcca tgtcggacat gcgctgaata
    48241 aaatttcaaa agacattatt gtacgtgcca aatctatgtc aggctatcaa gcgccttttg
    48301 ttccaggttg ggatactcat ggccttccta ttgagcaggt cttggctaag cagggggtta
    48361 agcgtaaaga gatggatctg gctgactatc ttgacatgtg tcgtcagtac gcgttaagtc
    48421 aggttgataa gcaaagagac gactttaagc gtctcggtgt atctgctgat tgggacaatc
    48481 cttatgttac cttagatcca agctttgaag ccgatcaaat tcgtgtcttt ggtgcgatgg
    48541 ctgataaggg ctacatttat cgtggggcaa agcctgtgta ttggtcatgg tcctctgaat
    48601 ctgctcttgc tgaggcagaa atcgaatacc atgatattga ttctacatcg ctttactatg
    48661 ctaatagggt taaagatggt aagggaatcc ttgatactga cacctatgtt gtggtttgga
    48721 cgaccacacc atttacggta acagcttctc gtggtctaac agttggacct gatatggatt
    48781 atgtggttgt tagacctgca ggttcagacc gtaactatgt ggtggcagaa ggactgctag
    48841 acagtctggc tgctaagttt gcttgggaat catttgagat tttggccaat cataagggct
    48901 ctgacttgga atacattgta accgagcacc cttgggacag tgaggttgat gagctagtca
    48961 ttcttggcga tcatgtgacg ctagattcag gtacaggtat cgttcataca gcacctggct
    49021 ttggtgaaga tgactacaac gttggtatga catatggact tgaggttgca gttacagttg
    49081 atgagcgtgg tttgatgatg gaaaatgcag gtcctgattt tcatggtcaa ttttatggca
    49141 aggtaactcc gattgttatt gaaaagcttg gagacctatt gcttgctcaa gaagtgatca
    49201 accactccta tccatttgat tggcgcacga aaaaaccaat tatttggcgg gctgttcctc
    49261 agtggtttgc ttctgtgtct gacttccgtc aagagattct agatgagatt gacaaaacaa
    49321 cattccaccc gacatgggga aagacacgac tctacaatat gattcgtgat cgtggcgatt
    49381 gggtgatctc tcgtcagcgt gcttggggtg ttccactgcc tattttctat gcagaggacg
    49441 gcacagccat tatgactaag gaggtaactg atcacgtcgc agatctgttc caagagcatg
    49501 ggtccattat ttggtggcaa aaagaggcta aggagctttt acctgaaggc ttcacacacc
    49561 caggctctcc aaatggggta tttaccaaag agacagatat catggacgtc tggtttgatt
    49621 cagggtcttc ttggaatggt gtgatgaatg ctcgtgatca tcttgcttat ccagctgacc
    49681 tctaccttga gggctccgat caatatcgtg gttggttcaa ctcatcactg attacctcag
    49741 ttgcggttaa tggtcatgca ccgtataagg ctatcctatc acagggcttt gtccttgatg
    49801 gtaagggtga aaaaatgtct aaatctaaag gaaatatcat ttcacctaat gatgttgcaa
    49861 agcaatatgg tgctgatatt ctccgtctct gggtagcttc tgttgataca gataatgatg
    49921 tgcgtgtgtc aatggatatc ctaggacagg tctctgaaac ctatcgtaaa atccgtaaca
    49981 cgcttcgctt cttgcttgct aatacatcag acttcaatcc acatacagat aaggtggctt
    50041 atgctgagct tgctgctgtt gataagtaca tgaccatcaa gtttaacaag ctagtaggag
    50101 ctatcaatac tgcctatgag cgttatgact tcatgacgat ttacaaggct gtggttaact
    50161 ttgtgacggt tgacttatct gctttctacc ttgattttgc caaagatgtg gtctacattg
    50221 aggctgctaa cagcctggca cgtcgtcgta tgcagactgt cttttatgat attttggtta
    50281 atatcactaa gctattgact ccgatccttc cacatacggc agaggaaatc tggtcatatt
    50341 tagagcatga gccagaagac tttgtacagc tatcagagct gccacaggct cagacttttg
    50401 ataatcaaga tactatccta gaggaatggg aagcctttat gacgcttcgg gcacaggcgc
    50461 aaaaggcttt ggaggaagca cgtcatgaca agattattgg taagtcctta gaagctcatc
    50521 tgacaattta tgcaagtcca gaggttaaga cactgttgac agctctagat agcgatattg
    50581 cactgctatt gattgtctct cagctaacca ttagtgagga gccagctcct gagaatgctg
    50641 tcagctttga tgatgttgcc tttacggtag ctcgtgcgca aggagaggtt tgtgagcgtt
    50701 cacgtcgtat cgatccaacg accagaatgc ggtcttataa tgcctttgtt tgtgaccaca
    50761 gtgcgaaaat tatcgaagaa aacttcccag aagcagtagc agaaggcttt gactcagctg
    50821 ctaattaagc aactaacagc tctgttcccg agttaaataa gcattggcgt gcttttgcca
    50881 atccagcagc aaggtgctag tcggtctggg cgtacctgcc ttactaggga ctctttgtgt
    50941 gggagctgat aagtgacctg ccttgagctt ggcaggtcta ggcttcttta taggttcacg
    51001 atttacgatt gactgggctt agagaagggc tagtcctgct aggcggcatt ggatatgaac
    51061 tgagtagtca tcatagctat aaaaaaacaa gcgcagactc acgtcagctt aatcgtgagc
    51121 ggcgcttgtt ttttcttggt tggggggtga aggcgaggag ctattaaagc taatattaag
    51181 cgatcaaaaa agcctagacc actagtcatg ttgtctaagc ttcagctgtt agagaggagc
    51241 tttctgagtg gaaggtagcc tatgctgata ggtgctgcct tagcctttta gcagtagtat
    51301 taaggctaga cagacgtctg gaaggaaatt tcaatcaaat tattggtgtg cagggttttt
    51361 gagtgacctg gaatcacaat agattggtca atcttacgct ttaagaaaaa ttcgcgaatc
    51421 acttcaagct cgtcctcttt gatggcacga tatttatttg aaatgagtag ctcataatgc
    51481 ttgggtgctt gcgtaaagat gacgtcagtg ttaccagctg agtaaacttc aacgaggtga
    51541 gcatctgtat tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata
    51601 agtctcataa atcttctcct gactattttt acttttatta tagcactatt tttaaattga
    51661 ttacggattt taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg
    51721 ctttaagact gttatggcgt ccgcaatagg aagaaaccaa gccagatggt taaagtcttc
    51781 caagggcttt gagatagctt ggaatgatgt cacctcgtac aggtaggcag gattatagta
    51841 gtaggtatcg cggtgacgag aatagaagta ttcgtctgct tgaccataat aataaccaat
    51901 atcagcagca aatcccagct cctcaactag ctcacgctcc agtgcctgta gctggctttc
    51961 accagcctct atttctcctc ctggcaaaaa ccaagcacca tttggagcct gcactaggat
    52021 aatctctgtt ttagccgagt taggaatcac tgcatagaca ccgtaacgtg cggtgtaatg
    52081 ctggtcatct atcttatcac caaatattgg aacggtcata tcgcttctcc tttgttttat
    52141 tatactaaat ttttggtcat tattctcata aaactgtaga tttatcaaaa atgtttcata
    52201 aaaaaatgct cgtcaaaaag agagaaaatg ctgtctgctt ttctctctgc ttttctctct
    52261 gctttttggt atgccctgtt agtccgcctg cttcgcctga gatttgacta caggcttgat
    52321 tataatgtgt ccattagagg tcaagacagc tcgcatgtct ttttctgctg ggtgctcaag
    52381 gtagaagtca gtaatggcgt cctcaatgta gtcctgaatg gtgcggcgca atggtcgtgc
    52441 tcccatctta ggatcatagc ctagctcaac gagcttttct ttgacctttt gggtgacatc
    52501 aaggcgaatg ttattgtgag caaggcggtg gttaacatca tcgagcatta aatgaacgat
    52561 atgtaaaaga ttgtccttgc ttagtggctg aaactcaata atgccatcaa agcgattcat
    52621 gaactcgggg ctaaagaaat gactgagctc tcctaaaaca gagtttgtcc gcccttctct
    52681 agcagcgcca aagcctactg aggcctctgt tttgccagtg ccagcatttg atgtcatgat
    52741 gataatagtg tccttaaagc taacggtacg tccttgtccg tcggttaatc gtccgtcatc
    52801 taggacctgt aaaaacatgt gcatgacatc agggtgagcc ttttcgatct catctaacaa
    52861 aatgagcgag taagggttgc ggcgcacctg ctctgttaac tgacctgcct cctcatagcc
    52921 gacgtagccg ggaggggcac cgacaagctt agccacagcg tgcttttcca tgtattcaga
    52981 catgtcaaag cgaatcatgt tatcagcaga gccaaaaagc tcaatggcta attgcttgga
    53041 aagctctgtt ttaccgacac cagttgggcc aacaaagagg aaggagccga taggacgatt
    53101 tggggctccc agtccaacac gattacgacg gatagctttt gcaattttat caacagcatc
    53161 gtcttgaccg ataacatgct ttttgagatc ggcggccaga ttgactagct gtgattgttc
    53221 cttttccttt aaatcaccaa ctggaatatt ggttttttgc tcaacgattg cttcgatggt
    53281 cttgtcagtg atgattggaa tatcctgctc atctagcttt tgagcctgca tttctttata
    53341 tttggcgatt tgatcgcgga aataggctgc tcgctcataa tcctcatcac gtgtggcttg
    53401 tgtcttgagg ttttcagcct caatcaaacg cttatcaatg tctttggggt caacaaagtt
    53461 aagggttagg ttcatctttg agccggcttc atctagcagg tcaatggcct tatcaggcaa
    53521 gaagcggtct tgaatatagc ggttggagag gttagcagct gcttcaatag ccgactggct
    53581 atatttgaca tggtgatagt cctcatattt gggttggatt ccttttagga tagtgattgt
    53641 ttcttcaacc gaaggctcgt ccaccttaac cggctgcatg cgtcgctcaa gggctgcgtc
    53701 cttttcgatg atgcgatatt cattgagagt ggtcgctccc actaattgaa gctcaccacg
    53761 agcaagtgct ggctttaaaa tatttcctgc gtccatgctg ccgtcaccaa ctgcaccagc
    53821 tcccacaatt tcatggattt catcaataaa tagaatcacg tcatggcgct tgcggatttc
    53881 ctccatgagc ttttgcatgc gctcttcaaa ttggccacga atacctgtcc cctgaacgag
    53941 gctaaccaca tcaaggcgaa tcacctgctt actctgtagc ttttgtggca catcgccatc
    54001 aacgattttt tgagcaaggc cttcaacgac agcagtctta ccaacacctg gttctccgat
    54061 taggacaggg ttatttttgg tacgacggtt gagaatctcg atcacgcgga taatctcatc
    54121 gtcacgtccg atgacaggat caatatcacc acgcttagcc atttcagtga tattaatgcc
    54181 gaattcctca agcaaacctt tgttagcctc ttgtgctggc tgtgtgtgat tgggacggta
    54241 gccattgtga cctccgccat tatggccgcc tgattgggta ggtggtgtat tgggcaattg
    54301 accgaaggct ctaaaattgt tcaggtcacc aaaaaagtca tcaaagaaag ggttttgaga
    54361 aggctgctgc gccttttggt tgccattata gcctcctaag ataggatttt tagggtctgt
    54421 tttcatgatt tggtagcaat tttgacagag gtcaatctgc ctttgctttc cgttaatgct
    54481 tgtataaaga tgaatggttg attcgtttaa attacagttt tgacaaagca tatcatacct
    54541 ccaaggggtt atctaaaaag tcaaggtcat ttagtcaaaa atggtcaaac tttatagtca
    54601 tattatagca ccttaggctt ggaaatcaag taaaaagctt cattattagc actttcaggt
    54661 atagagtgat aatctctata aatcttgctg ctcattggtt caaaaaagtc gtcaaagggg
    54721 ataaaataaa gagaaaatgg ctacttttct tgtttgtttt cgatgattta tgttaaaata
    54781 tatagggaca ataaacgaat aggagaaacg aaatggaatc acatttagtg agaatcatca
    54841 accgtctgga gctgatggta acagatggcg gtaatttaaa gagaaacttt gagcgagatg
    54901 gtgttgttgt tgcagaggtt gcatttgtca acgatcctga aaatggtcca gtctttattt
    54961 tacgtgatat tgaagcgcgt gagtcatatt catttgatag catcgatttg attgcgatgg
    55021 aaatttacga tttgttatat taagctattg atgatgacat gggcttgctg ggaggcaggt
    55081 cagacagagg acaagctggt gatttactgg tttgttttta ttatccctta aagcctcaag
    55141 acagctccag gaaaggcctt tctcctatgg tctttctagc cggtagggct tgatagtgat
    55201 taatagtgat ctgctctagc acggtcttga gcttttactg tcagaggctt gtgaccttag
    55261 ccactcgcag taaagggtac tggcccagta agcaaggtag gctaagtatc aatgtgaagt
    55321 tctaaccttg atcttagtga aatatttttg aggtgaatta agatgttaaa agtccttaga
    55381 atgctcattt ctaagggttt tgttgtgtct agctgttggt gtttgaaaga gcggtggtat
    55441 gataaagaga ggtcagaaaa gacctctctg atgtttgtga ttagctgtta gctattgcca
    55501 taggggaaag acacaatagc tagcttagct tttctttttc tttaggttta ggacgcctgc
    55561 gctagtgatg acgctaaggg ctgcaagggt gaagaatggg tgatttgtct cccctgtagc
    55621 tggtagcgtg ctcttttgag ctgctggtgc tgacttaggc gctggtgctt taggctgagc
    55681 tgatttttct ggagcctttg gtgcaggtgt cttttcaggt gcttttggag ctgatggttt
    55741 tgtatctttt ccttgatcac cctttggttt ttgctcgcct ttttcgccgc gttgtccttg
    55801 ctcgcctttt tcgccgcgtt gtccttgctc acctttttca ccgcgttgtc cttgctcacc
    55861 tttttcaccg cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cacctttttc
    55921 accgcgttgt ccttgctcgc ctttttcacc gcgttgtcct tgctcacctt tttcaccgcg
    55981 ttgtccttgc tcaccttttt caccgcgttg tccttgctcg cctttttcgc cgcgttgtcc
    56041 ttgctcacct ttttcgccgc gttcgcctct gtcaccctta gggccggctg gtccttgttc
    56101 acctttagga cctgtttctc cggtttcgcc tttatctcca cgtggtccca taggcccaac
    56161 aggaccttgc tctccgcgtt cccctctagg tccggcaggc cccacaggtc cctgaggacc
    56221 acctttttta gcttgtagtt ctaagttttg taagtaggtt tgcatgaatt gtcttaatgt
    56281 atgtaggtat actcttactt cgccatctcc gagtccgtcc ctaattagtt cagctggatc
    56341 tggataggac tctaatcgcg tataatcttc agctcgggca tttccagctg ttcctaggct
    56401 ggccattgtt gctagggcaa tggctgctga gcagacgctg tacttgcgta ttgttttttt
    56461 catctttctc tcctttgatg atagtatcat tactttttca aaattctttc ccgaagaaga
    56521 gtttaacatg gtagcttgct atgagaaaca gctaggcgcc actttgtctc cgtagttttt
    56581 ttaattcaat gctgaatcgt ctgattttat cagagggtta ttgtttttaa aggcgaggag
    56641 ttgctttgct cagctagtct agcaagttca caggtcagct tatgtttctt atcaagcttg
    56701 tttgtttttg agaatatttt tcgataaaaa gatgttgtat taatattcat gttatagtat
    56761 aattatattc gttgccatga ctttatgaat gttaggagat aggaatggat tttacctttt
    56821 tacccaaata ctgggcttat ttcaattatg gtgtgcttgt aaccatgatg atttcagcct
    56881 gtgttgtctt ttttggcacg attataggtc ttttagtgac cctgataaaa cgcagtcata
    56941 tcaagccttt gtcttggctt gtcagtcttt atgtctggat ttttcgtgga acgccgatgg
    57001 tggtacagat catgattgct tttgcttggc tgcatttcaa cgatctgccc attgtaggct
    57061 ttggtgtgtt ggatttggat ttttcaagac tgcttcctgg tattattatt atttccttga
    57121 atagcggtgc ttacatatct gaaatcgtca gggctgggat tgaggcggtg ccaaaggggc
    57181 agctggaggc tgcttactct cttggtatcc gtcctaagaa cgccatgcgc tatgtgattt
    57241 tgcctcaggc ctttaagaat attttgccgg ccttgggcaa tgaattgatc accattatca
    57301 aggatagtgc cttgcttcag acgattggtg tgatggagct ttggaatgga gctcagtcgg
    57361 ttgtgacggc gacctatctg cctattacac ccttgctgtt tgcggccttt tattacttga
    57421 tgataacaac aatattgtcg caattattag gctgcttgga gcgcaagcta gcacagggag
    57481 ggagataaga tgactgagac agtgatttcg attcgtcagt tgcataagag ctttggcaag
    57541 catgaggtgc taaaaggaat agacctgacc attaatcagg gtgaggttgt ggtgattatt
    57601 gggccatctg gctcaggaaa gtccacgcta ttgcgcacga tgaatttgct tgaggtgcca
    57661 acaaagggac acatcagctt tgagggcgtc gatattacgg ataaggcaaa tgatattttc
    57721 aagatgcgtg agaagatggg catggttttt cagcagttta atctgtttcc caatatgaca
    57781 gtgctggaaa acatcaccct gtcacccatc aaaacaaaag gaatgtcaag ggctggcgcg
    57841 gagcagagag cttatgagct gcttgagcga gttgggctga gagataaggc tgctgcctat
    57901 ccggcaagct tatccggtgg tcagcagcag cgcattgcga ttgcgcgcgg cttggcaatg
    57961 gatcccgatg tgctgctctt tgatgagccg acctcagcgc ttgaccctga gatggtgggt
    58021 gaggttttgg ctgttatgca ggatttggca aaatcaggca tgacgatggt tattgtaacg
    58081 catgaaatgg gctttgccaa agaggtggcg gatcgcgtga tttttatgga cggtggtctt
    58141 gtgattgaag agggcagtcc agttcaggta tttgaagctc ctaaggagga gcggaccaag
    58201 gactttttga gcaaggtatt gtcatagctg gcgcagctaa agggcagcat gtcacctcaa
    58261 ggtctggcta ttagtcaatt ggctgtttgt tttgggcatt ttgtttgtaa aaggcttaga
    58321 aagtctggtt ggtgctgtag ccatatctgg ctttgctacg cttgggctgc tagctggtca
    58381 gtgggtatca tagtgattgg aggtgtggtc tctttattgg tcaacattgc tgtggcaggc
    58441 tagcacaggg gctttgcttg ttgtgctggg taaggggttt catttgcatg actgttaaca
    58501 ttgcttaatt gatgaattag gttgactttt gttttattgt ttgatactat tcaggtaagt
    58561 ctgtcattag aaagcgcttt gcttttttga tgatggaaat catgatcata tgatcacgtc
    58621 ttaggtaata tgttgttgtc aacatggtgg tctgaaagta ggaggataat atggactaca
    58681 aagctgttta tcaggagtgg ctgcacaatg attttttcaa tgaagaaatc aaggcagatt
    58741 tagaggcgat taagcatgat gaggctgaga ttcaagaccg tttttataag gtgcttgagt
    58801 ttgggacagc aggacttaga ggaaagctcg gtgctgggac caaccgtatg aatatttaca
    58861 tggttggtaa ggctgcgcag gctttagcta ataccattat tgatcatggg ccagaggcag
    58921 tctcacgcgg gattgccatc agctatgatg tgcgctataa gtctaaggaa ttcgcagaat
    58981 tgacctgctc gatcatggca gccaatggga tcaagtctta tatctacaag gggattcgtc
    59041 cgacaccgat gtgctcttat gcgattcgtg ccttgaactg tatctctggt gtcatgatta
    59101 ctgctagtca caatcctcag gcctacaatg gctacaaggc ttattgggaa gaggggtcac
    59161 agatcctaga tgacattgct aatcagatag cggttcatat ggacgctatt gagcgctttg
    59221 aggacgttaa gcagataccc tttgaggagg cattggcaag tggtctgacc agctatattg
    59281 atgatagtat agaggaggcc tataagaaag aggttttagg cttgaccatc aatgatactg
    59341 atattgataa gtcagtgcgt gtggtttata cacctttgaa tggcgttggt aatttgcctg
    59401 ttcgtgaggt attgaagaga cgaggctttg atcatgtctt tgtagtgccg gagcaggaaa
    59461 tgccagaccc agatttcaca acagttggtt atccaaatcc agaggtacca aaggcctttg
    59521 cttattcaga aagactaggg caagaagtag gagcagctat tctgattgcg actgatccgg
    59581 actgtgatcg tgtggcacta gaggttcgag ctgctgacgg tagttatgtc tttcttaatg
    59641 gtaataagat tggtgctttg ttgtcctact atatcttttc acagcgtcat gctaggcata
    59701 atcttcctga caatcctgtc cttgtcaaat caattgtaac aggggattta tcaaaagcta
    59761 ttgccgctaa atatgacgtt gaaacggttg agactcttac aggctttaaa aacatctgtg
    59821 gtaaggctaa tgactatgac atcacaaagg agaagaccta cgtctttggc tatgaggaaa
    59881 gcattggttt ttgttacggt acctttgtgc gtgataagga cgcggttagc gcctcaatga
    59941 tggtggtaga aatggctgcc tactacaagc aaaggggtca gtcactctta gatgtgcttc
    60001 aagacattta caaggaattt ggctattaca atgagcgtca ggtagcgcta gagctagagg
    60061 gtgttgaggg gcagaagcgt attgcacgta tcatggagga ctttagaaat gagcctattg
    60121 agcatgcagg tgctatgagc ttgaagacca ttgtagactt taaggacggc taccttgatt
    60181 ttccaaagca aaattgtttg aaatattatt ttgatgatgg gtcatggtat gcgctgagac
    60241 catctggaac agagcctaag atcaagcttt acatctatac tattggtgaa acagaggcag
    60301 acagcattgc taagctagac gctattgagt cagcttgtca agcaaagatg gacagtgtca
    60361 gctaattgtt caagctctgc aacagaaaat cagctaatca ataagcaaaa aggaaaagga
    60421 agtgacagtg cttccttttt tcgttataat agttaaaaaa ttagcaagga gtgcatatgg
    60481 tacagattat tgatgggaag gccctagcac agaaaatgca ggcagcattg gctaagaagg
    60541 tagagagctt aaaggcagaa aaaggaattg ttccaggcct tgttgtcatt ctggtaggag
    60601 acaaccctgc tagtcaggtt tacgtccgta ataaggaacg cgctgcctta gcagcaggct
    60661 ttaaaagtga aaccgttcgc ttgtctgatt cagtctgtca ggaagagttg atagagctca
    60721 ttgagcaata taatcaagat gatacgattc atggtatttt agtgcagctt cctcttccgc
    60781 accatattaa tgacaaaagc attatccttg ctattgatcc taaaaaggac gtcgatggct
    60841 ttcaccctat gaatacaggt catctgtggt caggtcgtcc gaatatggtc ccttgtactc
    60901 cggcagggat tatggagatg tttcatgact atggtatcga acttgaaggg aaaaatgctg
    60961 ttattgtcgg gcgctcaaat attgttggga agcctatggc gcagctactg ttggataaaa
    61021 atgctacggt aacgcttacc cattcgcgca cgcgccgact ggcagatatt tgtcgtcgtg
    61081 ctgatatctt gattgttgct attggtcagg ggcattttat cacaaaggag tttgttaaag
    61141 agggtgctgt tgttatagat gttggtatga atcgtgacgt caatgggcga ttgattggag
    61201 acgtcgcctt tgatgaggtg tcagagctgg ctagcatgat tactcctgtt ccgggtggtg
    61261 ttggaccgat gaccattact atgcttttgg agcaaaccta tcaagcagct ctaagaaggg
    61321 tgagtcaatg attatagatc aatcgtttgt tgctagggtt gttgttccgc ggcaggctga
    61381 ctcccataag gggagttacg gcagagtact gttagtaggt ggcttgtatc catacggtgg
    61441 tgctattatt atggtagcgc tggcctgtgt tcatagtggt gctggcctag taactgttgc
    61501 aactgataga gaaactattg ctgccttgca tagtcatttg ccagaggcga tggctattgc
    61561 ggtagatgat gaggaattac tgttatctca gctaggtatg gcagacctga ttttgattgg
    61621 tccggggctg tcggagaata gcagagcagc taggctgttt gaattggtcc ttgcacatgt
    61681 cgctgatcat caggtattgg tcattgatgg ctctgcctta aggcttttag cgaaaagggc
    61741 agctgatgtt aagcagctga ggtgccctct tgtgttaacg ccacaccaaa aggaatggga
    61801 ggcgctgtca ggtttagcga ttgatcagca gtatgatgct gccaaccaag cagctctcaa
    61861 gcattttcca agggctacga ttttggttgc taaaagctca gcaaccaaga tttatcatgg
    61921 caaccagatc taccggctaa gagtgggcgg accttatcag gctacaggtg gtatggggga
    61981 taccttggca ggtatgatag caggaatagc tgtccagttt ccagagtcaa gcttggtggc
    62041 taaggttgct tgtgcgacct atctgcactc tgcgattgct gatgagctgg caaagactgc
    62101 ctatgtggtt ttgccgactg ctattagcta tgagcttcct agatggctaa aggcaatcag
    62161 cacaggccag aagctaggtt gaggctgtgc tgcgaggtcg tttgggaaaa gcggttaatt
    62221 ggtaggcatg acagcagctg gtttcagtcg tttagctatt ttgagtttag agctgctagc
    62281 ttaagactgg gtgctgcttt atgattcaag gaagctatca ttggaaaaac ttgtgtcaag
    62341 ctgtagaagc cctagctggc ttcttttttt gtctcttttt tgctcactat ttatgtggaa
    62401 acatgatata attgcattag tatacagttg gagcagttag gcttcatgaa gtgaaaggta
    62461 aactgatggc agactattta tccgtcactc agctgacaaa atatttaaaa ttgaaatttg
    62521 atcgagaccc ttatctggag cgtgtctatc tcactggtca ggtatctaat ttcagaaaaa
    62581 gaccaaatca ccaatatttt tccttaaagg acgagggagc ggtgattcag gccaccatgt
    62641 gggcaggagc ttataaaaag cttggctttg atttagaaga gggcatgaag ctcaatgtgg
    62701 ttgggcgtat tcagctctat gagccaaatg gctcgtattc aatgatcatt gaaaaggctg
    62761 agccagacgg tattggtgct ttggcgctgc aatttgagca gctcaggcaa aagctggctg
    62821 gtgaaggctt ctttgatgag aggcataagc aggccctgcc gcaatttgtg acaaaggtag
    62881 gtattgtgac gagtccaagt ggggctgtga ttcgtgatat tatcacaacc atctcaaggc
    62941 gttttcctgg ggtgagtatt cttttgtttc caacaaaggt tcagggtgag ggggcagctc
    63001 aagaggttgc tgctaatatt actaaggcta accagcgtga ggatctggat ttgttgattg
    63061 ttggacgcgg cggtggctcg attgaggacc tgtgggcttt caatgaggaa atcgttgttc
    63121 aggctatttt tgagtctcgc ctgcctgtta tttccagcgt aggacatgag acagatacaa
    63181 ccttggctga ttttgtggct gatcgcagag ctgccacccc aaccgcagct gcagagctgg
    63241 cgacacctat tacaaaaaca gatattgtct cttggattgc tgagcagcag agccggtcct
    63301 atcaagcctg tctgcgctat atcagacaag ggcaggagcg ggtggataag ctttcttatt
    63361 ctgttatttt caggcagcca gagaggctct atgatgctta tagtcaacgc ttagataggc
    63421 ttacgacctc cttgatgacc acttttaaag agacattatc aggagctaag caggagcact
    63481 tgattttgga gcatcgttta gcctctgtca atgtacaggc aaggcttgag cgttatcagg
    63541 atcgtctggc aactgcgcat cgtctcttga tagccaatat gaccaatcaa tatgacagta
    63601 agctagcagg ctttgagcga gctcaagctg ccttgctgtc gcttgatacg agccgtatca
    63661 ttgcccgcgg ctatgccctg ttaaaaaagg acggtgtagt agctgcttgt gttaaggaca
    63721 ttaaaaaggg agatcatctt agtattatca tgcgtgatgg tcaattagaa gtagaggtag
    63781 aagatgtcaa cgaaaaaaat atttgaagag cgtttacaag aattagaggc tattgtgacg
    63841 aggctagaaa atggtgatgt gccactagaa gaggccatct ctgaatttca aaagggtatg
    63901 gtgctgtcca aggaccttca aaaaacctta caagcagctg aaaagacact tgttaaggtc
    63961 atgcaggcag atggcacaga gctagaaatg gatgcctaat ggataagcta acaagaatta
    64021 atgccacgat tcatcagtat tatgacaggc agtctactgt ttcagcagat ctggaggagg
    64081 ccattttata ttctgttgat ggtggaggaa agaggctccg tccactcatg ttattggagc
    64141 tgctagaggg ctttggtctt gccttgacag acgctcatta cgcggttgct gctgctgttg
    64201 agatgattca tacaggaagt ttgattcacg atgatttgcc tgctatggat aacgatgatt
    64261 accgtcgcgg gcgactaact agccacaagc aatttaatga agcaactgct attttggcag
    64321 gagatagtct ttttttggac ccttttgctc taatcgcagg ggcagatttg ccggctgacc
    64381 tgctggtgca attgattcag cagttttcct tagcgtcagg aacctttggc atggtcggtg
    64441 gtcagctctt ggacatgaag ggtgagcatc agctgctgga tattcaggag ctatctgata
    64501 ttcatgccaa taaaacaggg aaattgttga cccttccttt tgtggctgcg ggtatcatag
    64561 ctgagcagtc agcagacgtt ttgtcttgtc tgtgggaggc tggtaggctt gttggacagg
    64621 cctttcagat aagagatgat atattagacc ttacggctag ctttgctgat cttggcaaga
    64681 caccgcaaaa ggaccttgct gctgcaaaat caacctatcc gagtctgctt ggtttagagc
    64741 gctcaagggc tattttggag gagtctttga gtcaagcgct agctattttt agcagactag
    64801 aaagggaaga aggctttgag tctcaggcta ttatcaaaag gatcgagggg ttgcgactaa
    64861 atggctaaag aaagagtaga tgtgctagcc tatagacagg gactttttga aacgcgagaa
    64921 caggccaagc gcggtgtgat ggctgggcta gttatatcag ctataagtgg cttacgcttt
    64981 gataagcctg gtgaaaagat tgatgagggg atcgaactaa ggctcaaggg tgagaagctt
    65041 aagtatgtca gccgaggggg tctcaagctg gaaaaagcct tgcaggtctt tgggatctct
    65101 gtgcaggata aggtgacaat tgatattggt gcttcaacag gtggctttac agatgttatg
    65161 ctacaggcag gagctaggct ggtttacgct gttgatgttg gaaccaatca attggtctgg
    65221 aagctcaggc aggatagtcg tgttcgaagc atggagcagt acaattttcg ctatgcaaag
    65281 ctagcagatt tttcagaagg tcagccagcc tttgccagca ttgatgtgtc ctttatttct
    65341 cttagcctga tactgccgac attgcactgt attttgcagg aaggggcaga ggctgttgct
    65401 ctgatcaagc cacagtttga agcagggcgc gagcagattg gcaaaaaagg gattgtcaag
    65461 gatagactga ttcatgaaaa agtgattaag caggtggcag atactgctct taattgcgga
    65521 tttatcgtta aggggcttga tttttcgcct atccaaggtg gtcatggcaa tattgaattt
    65581 ttggctcatt tagtcaaggg aaagggctcc aaggctattg atgatcagct catacagagc
    65641 gttgttagca gtgcacataa ggaatttaaa cagcatgaaa aagagtgaac gattagattt
    65701 aataaaaaaa atggttttgt ctcatgagat tgagactcag catgagctat taaagctcct
    65761 agctgattat gggctagagc taactcaggc cactatttca agagacatga atgaaattgg
    65821 cattgtcaaa attccatctg gaactgggcg ttatgtctat ggcttgtcac aggatagtgg
    65881 caagcgggtg gtgcaaaggc ctgcctctat caaaaaaacg attttggaaa tgtctgaaaa
    65941 aacagcgggc ttggagcagc atattcacct caacgttgtt ccaggcaata gcaagctaat
    66001 caaacgttat ttgatgacag acttttcagg tcaattgttt agcctgattg cagatgatga
    66061 tagtttgctg ttgattgcaa aatcagaagc agacgctgat catatccgtc aggaattgtc
    66121 cctttggatg cagggattgg tctaaaaaat agagagaagc cgatgttatt agaaatttcc
    66181 attaagaatt ttgctatcat agaggaaatc tctttaaact ttgaaaacgg tatgaccgta
    66241 ctgactgggg agacaggggc aggaaagtcc attatcattg atgcgatgaa catgctgctg
    66301 ggtgcgcgcg caagcactga ggtgattcga catggtgctg ataaggcaga gattgagggc
    66361 ttcttttcgg ttgatgctaa tcctcattta gccgctgtgc tggcagaatc agggattagc
    66421 atggaagagg agttgattct tcgtcgtgat atttttgcta acggtcgtag cgtcagccgt
    66481 atcaatggtc aaatggtcac tgtcagcacc ctaaaaaaac ttgggcagtt tttagtggat
    66541 attcatggtc agcatgatca ggaggaattg atgcgtccac agctgcacca gcatattttg
    66601 gatagttttg gagatgaggc ctttgaccag ctcaagcagt cctatcagca gatttttgat
    66661 cgctataagg ctttgcgaag gcaggctctt gagaagcaaa aaaatgaaaa agaacatcag
    66721 gcgcgccttg acctgctggc ctttcagata ggggaaattg aggcagcaga tttggttaga
    66781 ggagaagatg acctgcttaa ccaagaaagg cagcgattgc tcaatcacaa aaagattgct
    66841 gataccttaa ccagtgccta cctttccttg gataatgagg acttttccag tctctcacag
    66901 gtccgctcta gcatgaatga gttgctgtct attgaggacc ttgccccaga gtatcagctt
    66961 atatcagctg gtgtgtcaga ggcttattat attcttgagg aggtcacaaa gcaattatct
    67021 gataccatcg accagcttga ttttgatgca ggcagattgc aggacattga gctgcgttta
    67081 gacagcatta atagtctgac aagaaaatat ggcggtggtg tgaatgatgt tttggactac
    67141 tatgccaata ttaccaagga ataccagtta ttaagcggag atgaccgttc ctctgatgag
    67201 ctagaaaggg aattaaaggt ccttgagaag caactggtga tgactgcctc acagctaagt
    67261 gacaagcgtc atgccctggc tctagagcta gaagccgaca tcaaagctga gctgagagag
    67321 ctttatatgg aaaaggcgga ctttaaggtc cactttacaa ggtcaaagtt taatcgagaa
    67381 ggcaatgaaa gcttagaatt ttatatctca accaatccag gtgagggctt taagccgctg
    67441 gttaaggttg cttcaggtgg tgagctttcc cgcttgatgc ttgctatcaa ggctgccatt
    67501 tctaaaaaag aggacaagac gagtattgtc tttgacgagg tggatactgg agtttcagga
    67561 cgtgtggccc aggccattgc taaaaaaata tataaaattg gcagctatgg tcaggtatta
    67621 gcgatttcgc atttgccaca ggtgattgct attgcagata accagtattt tatttccaag
    67681 gaaagcaagg aggagtcgac agtgtctaag gctaagctgt tgacacagga ggagcggatc
    67741 gaggagattg cgaagatgat tgcaggagct gatgtcacag agacagcaag aaatcaagcg
    67801 cgtgaattgc taggtaagga ctgagtatca tagcaaaagc agaacagtag ctttagagca
    67861 agcttgcctg ctgcacttgt cgctacatgt tcagaatgag ccacctgaaa ggcaagcaag
    67921 aaggctagct cttatgcgta tgctatcaga agctaagtct ttttgtctct tgcattggcg
    67981 agtgattgat tgataatatt atgataaata gaaggactaa aagaatactg actgaggagg
    68041 taaaatgctg aaaaaaagaa tgggcttggc tagtctgcta gtgttgatga cctttgtgta
    68101 tcagtgctgt tcagttactg ctgagcagta ttccgatact gaggttgagg tgctgcagat
    68161 tagcgaggag aaaagccaga tcatggaaaa tcaagaggcg cttaaagacc tcaccacgtc
    68221 gtctgatcag ctaaagaagg aagctttaaa gcctaaagag gcagctacca acaagagcaa
    68281 gcaagaggct tcgacagttt atttagctga ggacgatcct gtaaccattg atagctctga
    68341 cgaggaaagc aatcaagata tcatagcgga ttctgttcct gatttggtta ttaaaggtga
    68401 tcaggtggat gtatctgagg ttatggtctc tgtaaaggag gattcatcga aagttgctaa
    68461 gcaaagaact gacgcagcgc agcggtacag tatagccaag catcaattga cccaaaagct
    68521 tgaggccttt aatgcggcaa cggaccaatt gctgaccatg attgctaaaa aatctgattt
    68581 gactggtcag tattatgtgg ttgggcattc gttgggagaa atgctggctg ctcaaaatga
    68641 gaaaaagctt gctgagcaat tagtcatgca acaaaagcac aaaaaaggct taggctcatc
    68701 agtcactatt ttagacgaat taggacgtgt gatttctgac attagtggtc ataaaggcat
    68761 gcttcctttt aatcgtaaga tcagctttaa ggtacatcaa gtcagatacg atcttccact
    68821 aactggtgat cgaacagtgc tacctgccca gctggctggc ttactgcttt tactaatagg
    68881 tcttatgctg cctaaagtag ctaacaagaa aagctaagat atggtcttgg cttttttatc
    68941 ttttaagagg gtgagttttt gacagatgtt ttagctaaca ccaagagcta gataccagct
    69001 ttgctttatt tttaaaggag tgataaaata aagagacgat aaatgaggtt agaaatggaa
    69061 cttaagatgg gaactattaa aattgttgca gattcatcaa tgacgattga accagagcta
    69121 atcaaatctc ttgatattac ggttgtaccg ctttctgtca tgattgatag caagctgtat
    69181 tctgataatg agctaaaaga ggaagggcaa tttctacagc tgatgagagc tagtaagtca
    69241 ttgccaaaaa ctagtcagcc accggtaggg ctttttgcag atatttatga gcgattggtc
    69301 aaggaggggg cgacagctat tgttgccatt cacctctcac cagctctttc aggaacaatt
    69361 gaggcatcac gtcagggagc tgaaattgca gcagcaccag ttacggtatt ggactcaggc
    69421 tttacagatc aggctttgaa gtttcaggtg gttgaagcgg ctagactggc tcaagctggc
    69481 gctagccttg aggaaatcct tgaggcggta gaggatatta aacgaaagac agagctttat
    69541 ataggggtat cagcacttga gcacttggtt aaggggggac gaatcggtcg tgtgacaggc
    69601 ttgcttagct ccttgctgaa tattcgtgtg gtcatggaaa tgaaaaatga taccctgcaa
    69661 acacttgtta aaggacgcgg caataagacc tttactaaat ggctggatag ctatctagca
    69721 gaaaatagcc agcgacagat agctgaggtg gccatttcct atgctggtca gagggatttt
    69781 gctgatagcc tgaagaagac aatcgctacg gtctttgatg ggccaattac tgttttggag
    69841 actggctcaa tcattcaaac acatactggc gagggcgctt ttgcggtgat ggttagatat
    69901 gaataagcga gggtttttgg gaggccttat cttctttttc agtgtttttg ccttatcatt
    69961 tgtgatatta gctgtcctta ttccaaagtc tgacccacag ctgaagaaaa gtgattttct
    70021 aaaaaataag aagataagcc tcaattatat tgctattgga gactccttga cagagggagt
    70081 gggtgatctc accaaccaag gaggctttgt gcccttattg tctggtgatc ttggagacta
    70141 ctttaatgct accgttaata ctgaaaatta cggtgtttcc ggtaatacca gccagcaaat
    70201 tttaacgaga atgactgaga acaaggagat cacagagcag ctcaaaaaag ctaatctcat
    70261 gacattaacg gttggtggca atgatgtctt ggctgttatt cgcaagaact tagctaatct
    70321 taaggtatca agctttaaaa agccagcaag gcaataccaa gagcgcttac gcaaaatcct
    70381 tgatttggcc agaaaggata atcaggatct gccgatcttt gttttaggta tctacaatcc
    70441 tttttatttg aattttcagg agctaacaga aatgcagacg gtcattaatg actggaacaa
    70501 aaaaacacaa gaggttgttg atgactatga ccatgtttac tttgttccaa ttaatgatct
    70561 attgtacaaa ggagtagatg gtaaagaggg cattgtccag tcaacaggag agcaaacaac
    70621 gattgtgaat gatgctttgt tttcagggga tcattttcac cccaataaca caggctacca
    70681 aatcatgtca gacgcagtaa tggagacaat aagaaagaat ggaaaagaaa ttaaacctta
    70741 attggtggaa atgggctttt ttgctattat tggcttttaa tgcagccttt ttagcagtta
    70801 ttggaagtcg tattatacaa ataagagagc ctaagtctga gctgatcaat caaaaagcag
    70861 caaagaatat taaaataggg accttaacaa ccactaaaga gcaattaaat gaggcagtcg
    70921 ttagctacct aaaggatttt cagacggaaa aaatgaccta taaggtgtat gccacctcct
    70981 cgaccattct ctttgaagga acctatcagc tcttaggata tgaggtgccg ttatacattt
    71041 attttcagcc tcatcgctta accaatggtg cgatacagct gcaggttctc tccttttctg
    71101 tggggaccct ttctttgccg gaaaaggacg ttttgcaata cttgaaatcc agctataagc
    71161 tgccaaaatt cgttgaagtc ttacctaagc aatcggctat tattatcaat ctacagcaat
    71221 tggaaaatga tgccaacatc tatttaaagg ctcaaaagat tgatcttgtc aaggatgata
    71281 ttcgatttga catctataag aaatgagtct aactaacgtt taatacttga cctgtggctg
    71341 ttttttagat atgataatat ctgttaaagc gttaagctta ctaattattt ggaggattgt
    71401 taaatggcta acaaacaaga tttaatcgca aaggttgcag aagcaactga gcttacaaag
    71461 aaagattcag cagcagcagt tgacgctgtc ttttctgcaa tcgaagcttt tcttgctgaa
    71521 ggtgaaaagg tacaattaat tggttttggt aactttgagg ttcgtgaacg cgctgctcgt
    71581 aaaggtcgca acccacaaac tggtgaagaa attgaaattg cagcttcaaa ggttccagca
    71641 ttcaaggctg gtaaagctct taaggacgct gtaaaataat aaatcaaaaa aagccctatc
    71701 tcattaagct gtttagcctg tgagataggg ctttttccat taaggaagga gtcttgtttc
    71761 aataagtaat cttgtgtgat cgtctgaaag attagcgcca ataatttcta atgtgcactg
    71821 tcttgggaac aagagttcca tttcataagg ataaaatgag tagggctgta caaaagcagc
    71881 ctggctgcct tgagggacct gaattcttaa ttccactgag cgatgtggca tagcagcatt
    71941 tttgatggct gtagtactca taaagccttg ctttgtataa tgagtgcctg gcttgatcgc
    72001 tgataggatc tgcggatcaa aggtcttatc atggtagtaa cgagcgagtt cctcttcaga
    72061 agtgcccaat tctgttaaga atgtttcata aacatagcga tagacgatga tattccaagg
    72121 gatggttagc ttatgagtag cactatcaag taaggctaca gactgctgca gctgggcatc
    72181 caactggctg gtatctccca tcacctgttc tagggctagg ttaatagggc tggcagaggc
    72241 gtatgtatac tgatacatca tctttttttc tgcttctgta aaggctgttt gagacctcca
    72301 gcgattggtg ataatgtatt tggtaacatc aggctcacta aatttataat aaggcttaaa
    72361 gctattccca tagggctcaa aaacaactgt ttgtccttca tcataagact gtgccttgat
    72421 ggttgaaggc tgaacgacaa gcaacgataa gaaaaatgta aacaagcata gtgtacgaat
    72481 agctatcctt tgataagata actttgcgtt atgatgttga tgagtcattt agcttttcct
    72541 cctttacagt agtgccaaga gtgtcatcac ctaatgatga tgtctgttgc taacaggatt
    72601 agccttagtt gaaatgatta caaacttcct taatgtaaca aacataataa aaataaatta
    72661 tttttttatt atatattagt taagctcaga tgacaagcta tttgattttt ttctgagata
    72721 atgttacaag ggatttctaa caccaatgac taactcagat gaagggcttt ttcttggagg
    72781 attgcctata gttacaatag taggcaagac tggcagtcgc catgatacct attccaataa
    72841 cagcaaaggt tgctagatga acagaggctg gtatacaggt catgatggta gttgccagtg
    72901 gcattaagag aatagcagtt gtgacgattg agctaaagac tcgtcctagc aatgcctcag
    72961 gaactttttt ttgaacgata gaaaagaagt gaatgttaaa gattgttaaa aagcattcaa
    73021 accataaatt cccaagggca atcacaatga ctggaagctt caagagagcc atagctgtta
    73081 ttagaagcat ccctaggcca ctaaggccta gggataggag taagctttgc tgattatttt
    73141 taaagagctt gttagccata aaagctccta agatagcccc taaagctccc atcgaaagaa
    73201 gactagcata gcttgattgg ctgcctagca gctgattcga aaaaggaatt aaataattga
    73261 aagcagcaat aaagaaattc acaagagaag caataatcaa caaagaaaaa atgtcattgt
    73321 catggtagat gaattgcagc ccctccttaa tatctgttaa aagctgaagc ctattgcctt
    73381 ggctgctctg tttagtgatg tgcctttctt tgtccttgat tgtatataga catagaaagg
    73441 acaatagaaa gctaatgcta tctagagcca aggctgtttt gatgccaaag caatccatca
    73501 ctaaaaaagc aagcattggt gaggaaatac tgatgatttg agatacgatt tctagctgag
    73561 cattgaaatg aacaagtctt tctgtttcaa ctagtgtgac cacataggct cgaaaagcag
    73621 ttccagagaa ggcatacgat attgctaaaa gagcattaac agtgataagc ccataaagca
    73681 tgatagtagg gttagctatc agggctaaaa gtccgcagct gatagctccg atagcatctg
    73741 tccacaataa caattgtcgt cgtttataac gatcagcaat ggcgccaccg ataggattta
    73801 agatgagtga aataaggcct tcagctagct gataataacc caaatattgt cggccagttg
    73861 ctccgagtcc agcaatcccg ctgctgttgc tgtagtcgta aacagtattg cctattttgt
    73921 taatagctcg acttgcgagc agctggtagt cgtttttgcg catgataaaa cctccaaaag
    73981 attatgtggt tttattataa atcagttttt tagggtctta tgtttttttg caaataaggc
    74041 tagaggaggc tacaaatctt tcaaaatcct tttggtaatt gtgcgctagg tgaggacaat
    74101 ccaggctctc aaaaatggaa atagcagtag tcatatcctt aatgccagac aaacactgtc
    74161 ctctttggta gtcctctaag ccctttaaaa ataaaaagat ggttttttca tatagcttgg
    74221 tttcattatt gagtagggct agtatctgct tttgataata gcgcgcatag tcaagctgat
    74281 gtcggtggat acaggtttcc caaatattga gaagggtgat ggtaaccaaa tgcttattgg
    74341 ttgaaatgct ttcgtagtag gtatgattgt ttagaatttc ctttcccatt ttatctaata
    74401 agggaatatc aataaaaaga tagagatttc caattaaaat cagctcatag atatgccagc
    74461 tttcagtcct aaaaaggtag tcagtgacct catcaagata agccttagga aaaggaatgc
    74521 taggattgca tttacagata aagccttgga gtagaatgct gtttaaatag taacgattgg
    74581 tatcaggatc agcttggtgc tttgccaatt cctgcttttg cagctgcttg aatccctcaa
    74641 tatcgcgtgc atattccagc ttgatcagct gcgacatgaa ttgaatttgc tctgtctgtt
    74701 tgaagttggc agctatgtcc ataaattcgc tgatttccac ttgcatgctg tctaaagctg
    74761 ttaaaaactt tgttactgat agatcagatt cgccgcgttc aaagcgggat aactgagaca
    74821 aggacacgtc tttactggca agctgctgta aggtgatatt tctgttttgt ctaatgctgc
    74881 gaaatgcttt tcccaactga tgattagtca tattttttcc tcctctaatg agtatatcat
    74941 gtaaggcttc tgttgctgta ttttcccgta tgtgcaaacc ttgaaacttg tctgctgccg
    75001 ccacaaaggc atgaaaacat ttacactttt tgatagctat ttttatcatt gatgtagtct
    75061 ttttcgcaac atttgtacgg gatcatcaga ttaaaattaa gaaactgatg atgtgacact
    75121 gtaaacatgc taaaaatatg ttgaacaatg cctgtagctg gaaaatgggt acatgtattt
    75181 tcttcatgcc tgcgtcgtga cctgctgcta ttaaagcttg cttgaaaggg aaaaagagct
    75241 tataatagca gtgagaacat taaaaatgaa agtagagata tgccaataat tgttatcctt
    75301 ggacttgcta tcttttcggt ggttaaggtc attatttttc tatgctttta taaagcattt
    75361 gagaaaaaac aactaaagaa gctagaacag gatcaaaaag aaaccaagca ggcgattgac
    75421 caagaggagt caaaaaaagc ctttcccttt taacataaag ctagaaaaag tctgagacct
    75481 ttcgtctcag acttttttta aggcttatat tgtaattgac cacgaaaatc gtctagtgtc
    75541 tggtagccct tttcagccat aatgtcttgt agctccttag tgatacgctt aaaaatagct
    75601 ggaccttcct ggtgcagtgc tgttccaatt tgtaccatag ctgcgccgca taggatatgc
    75661 tcaaaggcat cacgtcctgt tttgacaccg cctgtgccaa tgatctgaat agaagagtta
    75721 agccgttggt aaaaggcatg aacattagcc agggcagttg gcttgatgta atcaccacca
    75781 ataccaccaa agccgttttt aggcttgatg acgacctgct catcatcaat aaccaagcca
    75841 ttgccaatgg aattaacaca gttggcaaag gctaaggggt attgattgaa aatggctgcg
    75901 gcttggtcaa aatggacaat atcaaaataa ggaggtagct tgatgcctag aggcttggtg
    75961 taataggaaa agatcttttt taggagctga tctgtggctt caaagtcata ggccagctga
    76021 ggcttacctg ggacattagg gcacgacagg tttagctcga caagtccttg ataatcagag
    76081 gcctgaatag cttttaggat agtctcggtt tcttcagcag acatgcccac aacagataaa
    76141 aagtggtgct tgcttgcttg atccttttgc atttctgtga caatatctaa ataatactgg
    76201 tagccatgat taggaagtcc cattgaattg attgagccaa gtgctgtatc tgcatagcga
    76261 ggctcagggt tgccctgtcg aggggctaga gtacctgttt ttgtcacaaa ggacccagcc
    76321 tcagaggcct caatggctag cagctcttcc ttggtcatgc aatacactcc agcagcgttc
    76381 atcaggcaat tattaaaggc aaatgtagcg atttttgtgg cagtagaaac catgttttcc
    76441 tccattttta gacaaatttt ttctattcta tcactagggc atgagaatag caaggcattt
    76501 ttgcaaaata cttgcttgaa ggctttcttt tgtgaggttt tagcgttttt catgatatta
    76561 acaaaatgat tttcaataaa gagaggaata gactagcttt tttgacctat tttttgtaaa
    76621 ataggagttg taaaaaggca agaagccttt aaacttaata aggagatatt aactaatggt
    76681 aaaattggtt ttcgctcgtc atggtgagtc agaatggaac aaagcaaacc ttttcactgg
    76741 ttgggctgac gttgatttgt ccgaaaaggg aacacagcag gctattgatg ctggaaaatt
    76801 gatcaaggaa gctggtattg catttgatct tgcctttaca tctgtgctta agcgtgctat
    76861 caagacaact aatcttgcac ttgagtattc tgatcagctt tgggtacctg ttgaaaaatc
    76921 atggcgcttg aacgagcgtc actatggtgg cttgactggt aaaaacaagg cagaagcagc
    76981 tgagcaattt ggtgatgagc aggttcatat ctggcgccgt tcatacgatg tgttgcctcc
    77041 tgatatggct aaagatgatg agcattcagc acatactgat cgtcgttacg ctcatcttga
    77101 tcattctgtt attccagatg cagaaaacct gaaggtaaca ctagagcgtg cccttccttt
    77161 ctgggaagat aagattgcac cagccttagt tgatggtaaa aatgtttttg ttggagcaca
    77221 tggtaactct attcgtgccc ttgtcaaaca catcaagcaa ttatcagatg acgagattat
    77281 gaatgtggaa atcccgaact tcccaccgct tgtgtttgaa tttgatgaca agctaaatct
    77341 tactgctgag tactacctcg gtggtgaata atgctgtgag gccagaccta gctctggctt
    77401 tttttgttat gtgataaaaa aggcgtttcc aacagaaatg tgatatgata gttaaaaagt
    77461 ggtaaaagaa gggaatctta tgaaagtaaa ggaacgccga gaagctatta cagataggtt
    77521 aagccaagca caagaagcca tctcagcaac tagcttagcc aaggcattgg gagttagtcg
    77581 tcaggtgatt gtcggagaca ttgccttact tagggcgcag cagcttgaca ttatttcaac
    77641 accaaaggga tatatcctgt caaatgcttt gtttagtcat cactattctg ctagaattgt
    77701 ttgccagcat ggacctgagc agacaaggca ggagttggag ttgatattag cacatgatgg
    77761 cattgtgacc aatgtggagg tagagcaccc tatttatggc atgctgacag caccgcttaa
    77821 cattaaaagc tcagctgata tcaataactt tattgaaaag ctcggagcct ctaaggcaga
    77881 attattgtcg tctttgacag agggtctgca cactcacctt ttgtcctgcc ctgatcagga
    77941 ggcatttgaa gagatcaaga gagatctagc agctgcaggc attctctatg gtgaacaata
    78001 atctgatagc agctggcttc acagggattt agtcttggct tgatagccaa tgtccctctt
    78061 ttgtcgtagg tgatagggac cgcaggacag ctcctagatg ctgaggccaa agtcttgtgg
    78121 ctgggcctca aatgaggtta aaagggaagg aagctgctat ggttatggtg aaagggctag
    78181 atttaccctt acttttttgc taggataatc ttttatgctg ttaggccgca gggcttggtg
    78241 ctgcaatggc tgagatgtgt ctgtcttttg tcttagcttt tggtgcttga gaagggctgg
    78301 gattgagctt atgctgtggt tgttttttga tttgctaggt gtcttgacat ctgtcgcgtt
    78361 tttggttata ctaacgacta gtaaaaggag atattatgac caaaaaacca acacaactga
    78421 ttgcctactc ttctattttg gtggcctttg ccatcttgat tccgatgata atgcccatta
    78481 agcttattat tggcccggct tcctttaccc tagctagtca tctgcccttg tttttagcca
    78541 tatttatatc cattccggta gcgatcttgg tggggatagg aacaggtctg ggctttttgc
    78601 tagcaggatt tcctatgatt attgttatgc gagccttctc acacgtgctt tttgcagcta
    78661 ttgcggcttt tatgctcaaa aggcagccta aatggctgga aacaccgtta agaacctttg
    78721 tttttgggat tatagcaaat gtgattcatg gcctagcaga gtttttagtg gtttatctga
    78781 tgacagcaac agcagcaact gatctttctt atttttggtc aatgctaatg cttgttggct
    78841 ttgggtcttt gctgcatggt atggtggatt tttatctagc cttatttatc tggcgcttct
    78901 taaggcagaa gggtcatcta tcagtgacaa gctaggattt ctgtgagtat ttatgtttta
    78961 gtagccaagg ctgttacagg ctgaggctct tttttctgaa agcgcttgca tttttttgaa
    79021 aaaatgctat actaaagagt gcgtttgtaa atatactaac aaaaggagat gtcatgaaaa
    79081 caccagaaca gatattagcc gcgacgatta cgattggtga gcataaggtt gcaaagcctt
    79141 ttttggctaa ggctatttta ggctttattg gcggtgcgat gattagtttg ggctacttat
    79201 tgtatgttag gattgcagct agtgggctgg agacctttgg cgctttttct agtattttgg
    79261 gtgcttgtgc ctttccgatt gggctgatca ttattttgat ggctggcggt gaattgatca
    79321 caggcaacat gatggcggtg tcggcagcct tttttgcaaa aaagattaag gccaaggact
    79381 tgatggccaa ttggctggtg attacccttt ttaatatttt gggagccttg ttcgttgcct
    79441 ttgtttttgg tcattttctg ggtctgacag ctactggcag ctttaaagaa gaggtcattg
    79501 aggtggccca tgccaagctt gctgcaactc ctctacaggc tattgtttca ggaattggct
    79561 gtaactggtt tgttggcctg gcgctttggc tgtgctatgg cgctagtgat gcgacaggta
    79621 agctccttgg aacctggttt cctgtgatga cctttgttgc ccttggtttt cagcatagtg
    79681 tggccaatgc ctttgttatt ccggcggcta tttttgaggg tggcgccagc tggatcgatt
    79741 ttgcgactaa ttttgctctc gtttatgtgg gcaatgtcct tggcggtgct atctttgtta
    79801 gtctctttta ttacaaggct tatgatcact ctaaggaagc ctgattagtg ctgttatatt
    79861 tttagactgg gagaccttat tctcagtctt atttttatat tttgtgataa aataggaaac
    79921 gacgtttaaa aaggaggagt tgataagcat ctaatatggc atcatggata aaaaagaaaa
    79981 aagcaagcat tcctaggcga attcatctcc tttttttggt gattgttttt ttgtttgttg
    80041 ccctgatttt gagattggca caaatgcaga tttatgagaa ggatttttac aaggcaaagc
    80101 tgacagcgtc aaccgtttac aaagtaaaaa gctctatgcc aaggggaacc atttttgacc
    80161 gtaatgggaa ggttctagtt tctaatcgta tcaaggacgt ggtaacctat acgagaagtc
    80221 ccaaggctag tgctaaggac attaaggctt tggctcatca gctagctgct tatattagct
    80281 atcctgaggc taaagtgaca gtcagagcca aaaaggatta ttatttggca gatccagagg
    80341 cttatgctaa gacggttcaa gccttacccc aaaaggacaa ggtggatcgc tttggtaata
    80401 aattagtcga agcacagata tatcaaaatg cggcagcctc tcttaaggaa acagacttga
    80461 cctattcaga ccaagagcta aaggttattg ctatttttaa ccaaatgaat gcagcagctg
    80521 tttttagcac tgtaaagctc aaaacatcag ccttatctga gcaggatatt gccatcatta
    80581 tggccaataa gtcaaaatta ccaggtattt cagttgggac agactgggag cgtcaggtgg
    80641 aggagacaag ccttgctgct attattggaa gggtctctag tgaggaagcc ggtcttccaa
    80701 aggaagaagc aaaggcttat cttaaaaagg gctattcgct taatgatcgt gttggaacct
    80761 cttatctgga aaagcaatac gaggaggtcc ttcaaggaaa gcatgaaatc agagaaatca
    80821 aaacgagcag atctggtgag gttatttcag ataaaatagt cgaaaagggt cagatggggc
    80881 ggaacctgaa gttgagcgtg ccacttgatt ttcaacaggg cgttgagcag atcttgaatc
    80941 agcacttcca gacagagctc aaaaatggtc aggctgctta ctcagaaggg atctatgctg
    81001 tggcgcttaa ccctaatacg ggagcgattt tagcgatggc aggtctatca cacaatccca
    81061 aaaccggtga gcttcaaaag gacgctttag ggactattac tgatgtgttt acacctgggt
    81121 ctgttgtcaa gggggcgacc ttggctgccg gctggcaggc tggagtgatt caggggaatc
    81181 aggtcttgat tgatcagccg attcaatttg gtggctccca gccgattaat tcttggttta
    81241 ccagcggtca gcaccctatt actgctagtc aggcgctgga atattcatca aatacttaca
    81301 tggttcaggt tgccttaaga atgatggggc aggattacgt gactggtatg accttggcca
    81361 atactggtat gaaggaaacc atgaaaaaat tgcgggcagc ctatgccgaa tttggcatgg
    81421 gagtggcaac tggcgttgat ttgcctggcg aatccagtgg ctacctcata gatcaatata
    81481 atactgcaaa tgttttgaca gaggcctttg gtcagtttga taactataca accatgcaac
    81541 tggcccaata tgtctcaact attgctaatg gcggcagtcg ccttgcgcct cacattgtag
    81601 aaggcattta tcaggataat gaccagtcag gaccaggtaa gctaagtaag gctattgaga
    81661 ctaccttgtt aaacaaggtg cacttagctg ctgatagttt agcgattatt caggacggtt
    81721 tttatcaggt ggtcaatagc ggtagtggct atgctacagg tagggctctt gcaggaggtc
    81781 ctgttaccat tagtgctaaa accggtaccg cagaaaccta tgctaaggat aaaaatggtc
    81841 aggctttatc tacctttaac ttgaatgttg ttgcctatgg tccgagtgct agtcctcaaa
    81901 ttgctgttgc tgtcatgtat cctcatgcga cagactctct agccaaggca catcaatacg
    81961 tggctaagga tatcattaat ttgtacatga agatgtataa aaaccaataa aggagaaacg
    82021 agtgctttac cctataccaa tcgcaaaatt aattgaaagc tattctaaat taccagggat
    82081 tggtgttaaa acagcgacaa gattggcttt ttacaccatt ggaatgtctg atgaggatgt
    82141 gaatgatttt gccaaaaatt tattagcagc taagcgagaa ttaacctatt gctctatctg
    82201 tggcaatttg acagatgatg atccctgcca tatttgcaca gatagcagtc gggataaaga
    82261 gatcatttta gttgttgagg attccaagga cgtttctgcc atggaaaaaa ttcaagaata
    82321 tcatggctat taccatgtgc tgcatggctt gatttctccc atgaatgggg ttggcccaga
    82381 tgacatcaat ctaaagagcc taatcacgcg tttgatggct ggagaggcaa cagaggtcat
    82441 tgttgcaacg aatgccacag cagatggaga ggcgactgcg atgtacatct cacgtctcct
    82501 aaagcctgct ggtatcaagg tgacgcgatt ggctagaggc ttggcagtag gatcagacat
    82561 tgaatatgct gatgaggtaa ccctgctgcg agcgattgaa aatcggacag aattatagct
    82621 tagcccattt tcagctctct gtcattagcc cttatgccat gtgataaggc cataaaggaa
    82681 ggcagatttt gtcagagtct tttgaaaagc aagctcgttt ttgttataat aagtggtagt
    82741 ctaattcaga tagggaaggt tatcaatgtc taaacaaacc ttaattttat tatacggagg
    82801 gcgttcggca gagcgtgaag tatcagtgct ttcagctgag agcgtgatga gagcagttga
    82861 ttacaccaaa ttttttgtta aaacctattt tatcagccag acaggtcagt ttatcaagac
    82921 acaggaattc tctagtcggc cgaccttaac agaaaggctg atgaccaacg acactattag
    82981 gctagagcag cagataaggc ctagtgatat ctacgaggag ggggctgttg tttttccagt
    83041 cttgcatggc cctatgggag aggacggttc tattcaaggc tttttagagg tgctaaaaat
    83101 gccttatgtg ggaactaata tcctctcatc aagtgttgca atggataaga ttaccaccaa
    83161 aagggtccta gagtcagctg gtatcccaca ggttgcttat accgtttata ttgaggggca
    83221 ggatttagac aggtgtctgg cagagactga ggcagtctta agctaccctg tgtttgttaa
    83281 gccggccaat atgggctcat ctgttggtat ttctaaggca gaatcagagg aggagttgcg
    83341 tgcagctatc ctgttggcct tgacgtatga cagtcgtatc ctgattgagc aaggggtttt
    83401 ggcaagagag attgaggttg gactgcttgg taataccgat gtcaaatcaa cccttccagg
    83461 agaggtagtc aagaatgttg acttttatga ttatcaggcc aaatacattg ataatgagat
    83521 cacaatggct attccggcag ctattgacga atcagctatg acaagcatgc gtacctacgc
    83581 agaaacagcc tttaaggcta ttggtgcttg tggcctgtcg cgttgtgatt tcttccttgg
    83641 tcaggacggt cagatctacc tcaatgaatt aaataccatg cctggcttta cgcagtggtc
    83701 catgtatccc ttgctctggg agcatatggg actgagctat gctgagctta ttgaggagct
    83761 agtcagatta gcacaggaaa tgtttgaaaa gcgtgaaggg catttaatat aagagacaaa
    83821 ggacggaagg agatatagca atcctctgtc ctttcgtttg gcctgattgg tagcgttttt
    83881 tggtcagaag cctttaaagc cctatcgtct acggttggct gtgccagctt tagcctgtct
    83941 atgaaggatc agcctgtagg cataaagtga aatagaaaga atattcctaa tatgttatgc
    84001 tata
//
LOCUS       DARYVE010000002        59764 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYVE010000002 DARYVE010000000
VERSION     DARYVE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59764
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            84..1283
                     /locus_tag="TVW25_000082"
                     /pseudo
     CDS             84..1283
                     /locus_tag="TVW25_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            1377..1532
                     /locus_tag="TVW25_000083"
     CDS             1377..1532
                     /locus_tag="TVW25_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1377765.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TVW25_000084"
                     /pseudo
     CDS             complement(1714..2179)
                     /gene="tnpA"
                     /locus_tag="TVW25_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TVW25_000085"
     CDS             complement(2466..2939)
                     /gene="tnpA"
                     /locus_tag="TVW25_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1377766.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            complement(3221..3586)
                     /gene="rplL"
                     /locus_tag="TVW25_000086"
     CDS             complement(3221..3586)
                     /gene="rplL"
                     /locus_tag="TVW25_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1377767.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(3651..4151)
                     /locus_tag="TVW25_000087"
     CDS             complement(3651..4151)
                     /locus_tag="TVW25_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1377768.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(4180..4315)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(4447..5088)
                     /locus_tag="TVW25_000088"
     CDS             complement(4447..5088)
                     /locus_tag="TVW25_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1377769.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(5085..5852)
                     /locus_tag="TVW25_000089"
     CDS             complement(5085..5852)
                     /locus_tag="TVW25_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1377770.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(5852..6604)
                     /locus_tag="TVW25_000090"
     CDS             complement(5852..6604)
                     /locus_tag="TVW25_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1377771.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(6615..7745)
                     /locus_tag="TVW25_000091"
     CDS             complement(6615..7745)
                     /locus_tag="TVW25_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1377772.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(7812..8498)
                     /locus_tag="TVW25_000092"
     CDS             complement(7812..8498)
                     /locus_tag="TVW25_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1377773.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(8532..9884)
                     /locus_tag="TVW25_000093"
     CDS             complement(8532..9884)
                     /locus_tag="TVW25_000093"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1377774.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(9937..10893)
                     /locus_tag="TVW25_000094"
     CDS             complement(9937..10893)
                     /locus_tag="TVW25_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1377775.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(10890..11741)
                     /locus_tag="TVW25_000095"
     CDS             complement(10890..11741)
                     /locus_tag="TVW25_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1377776.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            11843..13186
                     /locus_tag="TVW25_000096"
     CDS             11843..13186
                     /locus_tag="TVW25_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1377777.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            13186..13974
                     /locus_tag="TVW25_000097"
     CDS             13186..13974
                     /locus_tag="TVW25_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1377778.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(14598..15587)
                     /locus_tag="TVW25_000098"
     CDS             complement(14598..15587)
                     /locus_tag="TVW25_000098"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1377779.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(15829..17598)
                     /gene="lpdA"
                     /locus_tag="TVW25_000099"
     CDS             complement(15829..17598)
                     /gene="lpdA"
                     /locus_tag="TVW25_000099"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1377780.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(17807..19216)
                     /locus_tag="TVW25_000100"
     CDS             complement(17807..19216)
                     /locus_tag="TVW25_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1377781.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(19340..20338)
                     /locus_tag="TVW25_000101"
     CDS             complement(19340..20338)
                     /locus_tag="TVW25_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1377782.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(20418..21386)
                     /locus_tag="TVW25_000102"
     CDS             complement(20418..21386)
                     /locus_tag="TVW25_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1377783.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(21892..23802)
                     /locus_tag="TVW25_000103"
     CDS             complement(21892..23802)
                     /locus_tag="TVW25_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1377784.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(24212..24997)
                     /locus_tag="TVW25_000104"
     CDS             complement(24212..24997)
                     /locus_tag="TVW25_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1377785.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(25103..26764)
                     /locus_tag="TVW25_000105"
     CDS             complement(25103..26764)
                     /locus_tag="TVW25_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1377786.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(26974..27732)
                     /locus_tag="TVW25_000106"
     CDS             complement(26974..27732)
                     /locus_tag="TVW25_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1377787.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(27729..28598)
                     /locus_tag="TVW25_000107"
     CDS             complement(27729..28598)
                     /locus_tag="TVW25_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1377788.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(28612..29607)
                     /locus_tag="TVW25_000108"
     CDS             complement(28612..29607)
                     /locus_tag="TVW25_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1377789.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            29959..31629
                     /locus_tag="TVW25_000109"
     CDS             29959..31629
                     /locus_tag="TVW25_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1377790.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(31718..32956)
                     /locus_tag="TVW25_000110"
     CDS             complement(31718..32956)
                     /locus_tag="TVW25_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1377791.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(32946..34127)
                     /locus_tag="TVW25_000111"
     CDS             complement(32946..34127)
                     /locus_tag="TVW25_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1377792.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(34190..34666)
                     /locus_tag="TVW25_000112"
     CDS             complement(34190..34666)
                     /locus_tag="TVW25_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1377793.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(34844..35890)
                     /gene="rfbB"
                     /locus_tag="TVW25_000113"
     CDS             complement(34844..35890)
                     /gene="rfbB"
                     /locus_tag="TVW25_000113"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1377794.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(36082..36678)
                     /locus_tag="TVW25_000114"
     CDS             complement(36082..36678)
                     /locus_tag="TVW25_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1377795.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(36678..37547)
                     /gene="rfbA"
                     /locus_tag="TVW25_000115"
     CDS             complement(36678..37547)
                     /gene="rfbA"
                     /locus_tag="TVW25_000115"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1377796.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(37604..38713)
                     /locus_tag="TVW25_000116"
     CDS             complement(37604..38713)
                     /locus_tag="TVW25_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1377797.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(38768..39556)
                     /locus_tag="TVW25_000117"
     CDS             complement(38768..39556)
                     /locus_tag="TVW25_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1377798.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(39546..40232)
                     /locus_tag="TVW25_000118"
     CDS             complement(39546..40232)
                     /locus_tag="TVW25_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1377799.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(40306..40968)
                     /gene="nth"
                     /locus_tag="TVW25_000119"
     CDS             complement(40306..40968)
                     /gene="nth"
                     /locus_tag="TVW25_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1377800.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(40968..41645)
                     /locus_tag="TVW25_000120"
     CDS             complement(40968..41645)
                     /locus_tag="TVW25_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1377801.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(41712..42230)
                     /locus_tag="TVW25_000121"
     CDS             complement(41712..42230)
                     /locus_tag="TVW25_000121"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1377802.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(42310..42678)
                     /locus_tag="TVW25_000122"
     CDS             complement(42310..42678)
                     /locus_tag="TVW25_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377803.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(42687..44897)
                     /gene="recJ"
                     /locus_tag="TVW25_000123"
     CDS             complement(42687..44897)
                     /gene="recJ"
                     /locus_tag="TVW25_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1377804.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(44894..45658)
                     /locus_tag="TVW25_000124"
     CDS             complement(44894..45658)
                     /locus_tag="TVW25_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1377805.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(45658..46587)
                     /locus_tag="TVW25_000125"
     CDS             complement(45658..46587)
                     /locus_tag="TVW25_000125"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1377806.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(46602..47240)
                     /locus_tag="TVW25_000126"
     CDS             complement(46602..47240)
                     /locus_tag="TVW25_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1377807.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(47233..48471)
                     /gene="hflX"
                     /locus_tag="TVW25_000127"
     CDS             complement(47233..48471)
                     /gene="hflX"
                     /locus_tag="TVW25_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1377808.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(48556..49446)
                     /gene="miaA"
                     /locus_tag="TVW25_000128"
     CDS             complement(48556..49446)
                     /gene="miaA"
                     /locus_tag="TVW25_000128"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1377809.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            49579..49755
                     /locus_tag="TVW25_000129"
     CDS             49579..49755
                     /locus_tag="TVW25_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1377810.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(49911..50548)
                     /locus_tag="TVW25_000130"
                     /pseudo
     CDS             complement(49911..50548)
                     /locus_tag="TVW25_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(50705..52969)
                     /gene="glgP"
                     /locus_tag="TVW25_000131"
     CDS             complement(50705..52969)
                     /gene="glgP"
                     /locus_tag="TVW25_000131"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1377811.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMVGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(52995..54497)
                     /gene="malQ"
                     /locus_tag="TVW25_000132"
     CDS             complement(52995..54497)
                     /gene="malQ"
                     /locus_tag="TVW25_000132"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1377812.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(54704..55726)
                     /locus_tag="TVW25_000133"
     CDS             complement(54704..55726)
                     /locus_tag="TVW25_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1377813.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            55973..57226
                     /locus_tag="TVW25_000134"
     CDS             55973..57226
                     /locus_tag="TVW25_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1377814.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            57526..58887
                     /locus_tag="TVW25_000135"
     CDS             57526..58887
                     /locus_tag="TVW25_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1377815.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            58887..59723
                     /locus_tag="TVW25_000136"
     CDS             58887..59723
                     /locus_tag="TVW25_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1377816.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        17474 a        14027 c        11157 g        17106 t
ORIGIN      
        1 cattaacatt attcgtcata tttttacttt cattttcttt tcttggtcaa aaagaagtaa
       61 cggtatcgtc acgaggtgaa attatgccta caaaagtcat tgcatcaata cagtcaacta
      121 gcaacaatgc tatcgttaaa aataatctta aagaaaacca actcgttaaa aaaggaaaac
      181 gtttaatcaa atataaagaa accattgaga gttctcaaaa gaattctcta gaatcacaat
      241 taaatacgtt gaataaacaa aaagttggtt tagagacatt gaaagaaagt ctcaaacaag
      301 gaacgaacct cttaccacaa aatgatgaat ttggtcttgc tgacaccttc aacaacttta
      361 taaatcagtc tcaagagatt aaacttggta tcgctaaaat aaatacagaa gtatccaatc
      421 aatccacact tgcaaataac acccttgctg caattgatac tcaaatcaat actataaacc
      481 agcagatttc agaatatgaa gatcttcgtc aagctatctc aaatcataac acaatcttac
      541 caactggtaa tcctcatcaa gatattctca ataattatct gtctcaatca caagaagaat
      601 aaacttccac gtctaaccag tttatctctc agattaacca gactatttca ggtttagaat
      661 catccctctc tgggcttagc attcaaagag caggtactgg tagtagtgca acatacgata
      721 acagttcaga aaccaaagtt gaagtcttga ggactcaatt tctacagaat gcttcacaac
      781 agctgtcaac catcgacagt caaatcactg aacttaaagc tcagctagaa caagcaagtg
      841 tatagttaga cactaatgtt gttttagcac cagaaaccag gattattcat ctaaataatg
      901 aatacgaggg gaaaagtctt atcccaaatg gtagtgatat tgccaaaatc tatcctaata
      961 ttactcaaac tagaaaagct ctgattacat actttgtaac ttctgattat gtttctctcc
     1021 ttaaaaaagg tcaaactgtt cgtctaaatc ttcaaaaagt gagaaaacag tccatcactg
     1081 ttaatggaaa aatttctact attgataaaa cagcaacaaa aacagaacaa ggtaatcttt
     1141 tcaagattac aactcttgcc aaactccctt ccaaggatag ctacttgata aaatatggtg
     1201 cacagggtcg tgttacaagt gttatcgcta aaaaatccta cttcgacttt tataagaata
     1261 aactgttgtc aaatcatgat taaaccattc cggacgtttc gatgaccatt taggatttag
     1321 agaaataata tattgatctt aaattataat attagaaaaa agaaggaggt ccacaaatgg
     1381 aaaaacaaaa ttcactcact caatttcaag aactaaattc atccgaactc aatcaaataa
     1441 caggtggaga ttggtggtca gagatattaa attttaatcg ctctcaaaaa tataaacata
     1501 cctccgtggg ttctaataat attattgtct aacatatact tagtattgta ataatagttt
     1561 ttttagtaga aatcataacc acccgtccaa caggtggttt gaatagggac tataaaccca
     1621 tataactagc cagcgcctaa agacgctggc tttcactttg ttcaaaccac attgctattg
     1681 actcgtcact tgcctctcaa agaagtattt gtatcactta cccttatctc taaagggatc
     1741 ctcatattct tttacactca gtttatctag tgctatgtca tgtttttctt gttcttgaat
     1801 atattttttt attgtagctt catttaatcc aaccgtacta atataatagc cttctgccca
     1861 aaagtgtcga ttaccaaatt tgtatttcag attggcgtgc ttgtcgaaca tcataagcgt
     1921 actcttacct tttaaatatc ctataaaact tgaaacactt attctgggtg gaatgcttac
     1981 taacacgtgt acgtgatctg gcatcagatg tccttctata tatttctaca cctttatagc
     2041 tacataatct ttgaaaaatt tctcccaaac tgcctcgata ttgattatag attacttttc
     2101 gtctatactt aggggtgaac acaatgtgat atttacaatg ctactttgtg tgcgataaac
     2161 tgtggggctt ttgtgccata tttttactcc tttcgcttta caattggctt gaacacctat
     2221 attgtagcgc gtttggagtt tttttgtagt ataacgttcg atgcgtaccc gcatagcggg
     2281 ggatttttgt ttcgcaccta cggagcgaaa cggactaaag tcactaagtc ataaccacgc
     2341 gtaaaaacgg gtggcttgta caccggctat aagccgtttc tctccagcga cgtctaaaga
     2401 cgttcgctga acttcgttca ggttagtgct atgattactt gactaatgcc cgtaaaaacg
     2461 ggcttttatc ttgttttaaa actgccatct gaaaatggat cttcatattc tttaacactc
     2521 aacttatcaa gtgcaatgtc atttttctcc tgctcgcgaa tatatttcgc taccgtcctt
     2581 ttgttcagtc caacggtact aacatagtag cctctagccc aaaactttcg atttccatac
     2641 ttatatttta aattagcgtg tttatcaaat atcatgagag cacttttact tttcaaatac
     2701 cccatgaaat cggaaatcga aagttttgga ggtagcaaga cgagcatatg aacatgatct
     2761 ggcatcatat gtccctcaat gatttccacg cccttgtatt gacataggtg acggaaaata
     2821 tcaattaagt cctgtctaat tttgtagtaa atggattttc tgcggtactt tggtgtgaaa
     2881 actatgtgat atttgcacat ccatttggta tgtgataaac tgtaactggt tttagccatc
     2941 tctttttcct ccttgatcta acctgaacaa ttagattata acaggaaaaa gaaatggaag
     3001 ctcaaagcct tgtcagccac cagcatagct ggtggttttc ttgtttttct ctacgagaaa
     3061 aactggctcg aagccataat aaaaataaaa accctgccaa aaaatctttg gtagggtttt
     3121 tagcaggaaa ccaaatcaat ttatcagttt ctctaaatcg ctctaagcaa tcattaaacc
     3181 ttgatttact aggcttccgc aatcaaattg cgatactcta ttatttaaga gtgatagttg
     3241 ctccagcttc ttcaagctta gctttgattt cttctgcttc tgctgctgca acaccttctt
     3301 tgatgttagc aggtgcgccg tcaacaagac ctttagcttc tttaagtcca agacctgtga
     3361 tttcacgaac tgccttgata acaccaactt ttttgtcacc agcagatgtc aactcaacgt
     3421 caaatgaatc cttagtagct tcttcagcac caccagcagc agctacagct acaggagcag
     3481 ctgcagtcac accgaattct tcttcgatag cttttacaag atcgttaagc tcaaggattg
     3541 aagcttcttt aatttcagca ataatgtttt caatgtttaa tgccattgtc atttcctcca
     3601 aatagttata ttaaataatg atttgtagct ctaggctacc tctaaaggcc ttacgcagcg
     3661 ccttctttgc tttctgcaac agccttgaca gcgtatgcaa cgttgcggac tggagcttga
     3721 agtacagaaa gaagcataga aagcattcct tcgcggtttg gcaatgctgc aagtgcttga
     3781 atttcctctt ttgaagaaac aacaccttcg atagcaccac ctttaatctc aagtgcttca
     3841 gcagttttag caaagtcgtt gatgacttta gctggtgcga taacatcttc atttgaaaat
     3901 gctactgcag atggtcctac gaatatatct tttagctcgt caagacctgc tttttcagct
     3961 gcacgagtca agattgagtt tttgataacc ttgaactcaa cgccactttc acgaagtgaa
     4021 cgacgaagaa cagtatcttg atcaactgta agaccacgtg aatctacaac aacgatactt
     4081 acagctgctt tcattttctc agcgataagc tcaacttgtt cagctttttt agcgataatt
     4141 gcttcactca ttagttttac ctccgttttt atttttgggc taggcacaaa aaaatcgcac
     4201 ctaaacctag acacgaaagt acaaatacgt tatcttcaat aatgacgttt tgtgcctcgg
     4261 caggaatatt atgagcacgc tcccctgctg tcttaggtca gttttattca aaaccatagt
     4321 tagtatagcc tttttaaatg actttgtcaa cctatttttt agaaaatctt aaataaaaaa
     4381 ggaaagctct tggctttccg ctaaatagat ctgattagtg gctcaaaagc gcctcctaac
     4441 ttaagcctaa tgataagcaa cttgtgacga ttgattgcta taacttagcc cgatcaagct
     4501 ccacagtatc atctcataaa taaagaagaa caaggcaaag caatgcccaa aaaaggcctc
     4561 tggcaaaatc caaatgacag gatctgtcag cggatcaaac aaccagcttg aatctcctac
     4621 aaagagaatt tgatgaaaaa gggtaaagaa ctgatcaaag ccaatcatta aagcaaagca
     4681 agcaatcaca attggcaata aggctgctgc tattagccct cttcgaagca gcataaccct
     4741 tccttttttg atgctctgat aaaaatagat aatggttggc aacataagca ggctaaagat
     4801 cagctgtgtt atatgaaaca gcattttcac atctgtaaaa tgctttagac cagctcttga
     4861 tgctgaaaag ctggctagct ttagctcacg aacaaaagga ttggttaagt aagtcagcaa
     4921 tatattatag ttgtggagaa tagacttttt gcacatcaaa actgcctgct ctagttgcaa
     4981 ataatcaacc tcaatcggat aaagcagcca agataaatag atagttatca aaactgccag
     5041 tgctagtagc caaagccaac tggcaatgaa cttgcctttt tcaatcataa tagctcccac
     5101 tcatctaagc tagccaagac atgatcaggc ttaattggaa ggcttggaac ctcttttgcc
     5161 tttgtaaagc cggttgttac tagaatagtt gccatatcat tttgaattcc tgccatgata
     5221 tctgtcaggt aattgtctcc aaccatagcc acctcagaac gtggtacctt taagatctct
     5281 agggctttat tcatgataat cgcatttggc tttcctataa atactggctt cactctagtt
     5341 gctgcctcaa ggagcgcatt taaagcgcca gcacctggca ttagcccacg ctctgttgga
     5401 atatttaagt caggattggt cccaataaac aaggctcctt tttgaatggc aagtgttgca
     5461 attgataaca tttcataggt aacctcagta tctaagccaa caacaacata ggctggattt
     5521 tctgtatcct cggtatagcc tgcctctgca atggcagact ttaagccagt ctcgccaatc
     5581 acataggctg ttttgcctcg attcatatca ttcatgtaat caacggttgc cattgtagcg
     5641 gtgtaaatgg tttcaagacc tgtatgaacg ttaaattgat tggctagcat ttcctgaacc
     5701 atttcaggtg ttcttgtggt gttgttggta actaagagat aagggatacc tttttcctgt
     5761 aaacgcttga taaagcgctc accagccggg atacgatttt tcccttgata gatggttcca
     5821 tctaaatcaa ttaaataagc tttatagggc actaatttgt ctcactttct ttagtcgtta
     5881 taggctgcca tttgataatg gcctgcgcat taagctggcc tgatgacctg atctcatggt
     5941 aggaggtcaa atgctctaga tgatagcctg aggttatttg agtgctgggc ctcacctctt
     6001 tgatataggt caaggtaagg tggcaaggtc tgtggtgtaa taaaaattca tatcccaaaa
     6061 cgtcatacat ccaatccaaa tacttactat tattggcatg accattcata tcaatgtcaa
     6121 aataacgaac ctgataagct tgaaccatag gatcctgaag ctcatctatt ttgataggac
     6181 gcttgatttt cttaacaaag tcagcctgat aaggcaccac caaatcatct ggtatcgcag
     6241 ctgccttacg tgtttgagga tttagcaggg caaaatgaga taaaatggtc atgatggcat
     6301 gacctgcctg atcataaatg tgaaattgcc ggtaacaaaa taatttattg taagaaatag
     6361 cttgcgtttc aatggttact gtttccccaa accttggcat acgatcaatc gttacatcat
     6421 aatccgtaac aacccaaatc aagccatatt gctgaagtaa cacctcattg cctcgtccaa
     6481 tttcagctga ttgtcttgct gataccatta agcaatgtgc taataaaagg ggcagcttga
     6541 catcagcctt aacatcacaa aaatcaaaag acagcttaag gctttcgcta taccttaatc
     6601 ccataacaca cctcctaatc taagatgaat ttttcagcga cagaatcacc taaaaagagg
     6661 ccttttttgg tcattctgat aaagtccttg tcctctacca aaagcccctg attctgaagc
     6721 tctctcacaa caggaccata gcgtgactca aatgataggc caaatttttc ttgaaaccga
     6781 ctgactgata ctcctgattt ttttcgcaga ccaagaaaaa gctcctcctc catcatctcc
     6841 tccttggtga gcacttcctc acttaaccta gcatttccat ctgctactgc ctttaggtaa
     6901 tgctgaatag gaacccggtt gcggtaacga atcccatcaa gatagccaga agcccctgcg
     6961 ccacagccaa aatactcatc attattccaa tacatcagat tgtgcctgct ttcaaagcca
     7021 ggcttagtaa aattagaaat ttcgtaatgc tcaaagccac tggcttccat ttcagaaata
     7081 atatactcaa acatctcagc ttccaaatcc tcagtgggca aatggagctt gccacgacgc
     7141 attttgttca taaaaacagt gtgatgctct aggataaggc tatacaggct aaggtgagga
     7201 atatctaaag caagtgcctt agccacattt tccttgacct gctgcatggt ctgtccaggc
     7261 aaagcataaa tgagatcgat agacatattt tgaaagcctg cctccttaag actagcaatg
     7321 gtcgtataaa tctgagcctc agtatgactg cgtccaatct gctttaattg cttgtcatta
     7381 aaagtttgaa cgcctaggga aatccgattg acagccgatt gccttaatac tgcaatctta
     7441 tcctcagtca aatcacctgg attggcctcg atggtaaatt cttcaagctg gtctagctgt
     7501 aggtgctgct gcaaatggct cagcaaataa tcaagctgat tggctgttat ggctgttggt
     7561 gttccaccgc caatataaag tgtcttcaag gagctgatct gataggattc aaattcctta
     7621 atcagtgcct ctaggtaggc atcgacaggc tgatttttga taaatacctt agaaaaatca
     7681 caatagtagc aaatttgtgt gcaaaaagga atatgcacat aggctgaggt tggttttttt
     7741 gacatggtaa tattatatca ttttagctca gaaattcatg ccaagtgatt agctttttga
     7801 catgtactaa cctaaggctg cttctttttc tccattctca caaaggaatg actactccca
     7861 ttagcatact gctcaaagct tgaggttggc tgatagccca ttttttggta gaggctttgt
     7921 gcgcctttat taaagctagc gacatttaaa acataggttt cttgcggata agtagtgcta
     7981 gcaaaggctt caatgctgcc caaaaaagaa acaccatctt cctgaccagt agtatcaggg
     8041 gccataccaa gaccaatctc aagctctgat tcctgttcaa aaaagctggc aaagccaaaa
     8101 agaacaccat tgcgaagcac ttgaaagtaa tgctctccac gcgccttggg tgacaatatt
     8161 gactgatagt cctcaggatc agcagtcatg ctatagcact cataagctgg gctatagatc
     8221 cagtcatgcg caatgatttc agcactatgc tgtgtcatcg gcatcaggta aaaagaagac
     8281 tcagacaata agcgatgaaa ggtcttgttg atatgcttta tgcgacgccg ctgcacatca
     8341 ggctgatctg tttgataaat gtaattagca tagccctcct gatattctgg aatcattgtc
     8401 aaatacagct tttgggtcaa ctcatcaagc tgactagcaa tcctatccac tctatgcttt
     8461 atcatattac ctccaattct aatgctgctt gatagcataa aaagtgccga agcaacgaca
     8521 ctttttctag attaatcaag gccaatttcc gcacgaacaa ccgctgcaat ggtatcaaca
     8581 taatagtcaa cttcttcatt gcttggtgcc tctgccatca cacgcaacaa tggctctgtg
     8641 ccgctaggcc ttaccaaaat gcgaccatta ccagccattt ctccttccat ctgagcaata
     8701 acctcagcaa tagcaggcac ttccatagca cgctccttca tgctgttgtc aacacgaata
     8761 ttaacaagct tttgtgggta aatagtgacc tcactggcca attcggagag agttttacct
     8821 gtctccttca tgattttggt gagctgaaca gctgtcagtt gaccatcacc agttgtattg
     8881 taatccatga taatgacatg ccctgattgc tcaccaccaa gattgtagcc gaactgacgc
     8941 atctcctcaa caacgtaacg atcaccaaca gctgttacct tcttatgaat gccacagcta
     9001 tctaatgcct tgtgaaaacc aaggttagac atcactgttg tcacaatcgt atttttagct
     9061 agcaagccct tctcagaaag atacttgcct atgataaaca tgatcttgtc gccatcaaca
     9121 atagcaccat tttcatcaac agcaattaaa cgatcactat cgccatcaaa agccaatcca
     9181 atatcagagg ctgtttctgt caccaagtcc tgaagctttt cagggtgtgt agagccgata
     9241 ccatcattaa tgtttaatcc atttggattc tcaccaataa ctgtaatgtc tgcatttaaa
     9301 tctaaaaaga cattacgagc tgaaacagaa gctgcaccgt tagcagtatc aagagctatc
     9361 tttaaaccgt ctaaatctgc tccagtagta accaagaatc tctcgtactt gcgcaagcct
     9421 tctggataat caaccaaggc tcctaagccc tccgcacttg gacgtggtag gaggtcctct
     9481 ttggcatcta agagcgcttc gatttctagc tcttgctcat cagccaattt aaagccatca
     9541 ctcccaaaaa acttaatgcc attgtcaaga gcaggattgt gactagctga aatcatgaca
     9601 ccagcactag ccttttctgt acggaccaaa taggacacac caggagttgc aagaacacca
     9661 agcttataga cctctatccc aacagaaagc aagccagcaa tcagggctgc ctctagcatt
     9721 tcaccagaga tacgggtgtc acgagcgaca aaaactctag gcctttcagt ctcatgctga
     9781 cttagcacat aaccaccgaa ccgaccaagc ttaaaagcaa gctctggggt caactctaca
     9841 ttagcctcgc ctcgaacacc atccgttcca aaatattttc ccataattta tatcagctaa
     9901 acgcttcctc cattccattt tcctagctat tatgctttat tttttaattg ttgtcaactg
     9961 aacggttact accgaaggct ctatagaaac ctgatttgaa accaagctga ccgttttgct
    10021 cgtgtttttg gtgacgtcag aaatattgac ctctgccacc acctcatcaa tagtttcaag
    10081 gacctcccga ctaccagaaa taacagcggt ctgcttggag agcttatact ggatatctga
    10141 cagactgtca tccattagtc caactgcctc gactcgaata ggaactgatt tggtgatttt
    10201 tttgacagaa actgacaaat tagccttggc tggatcgatc gcactagcta aaatggtacc
    10261 atcggcagct actgcctgca gggttactcg gctgctataa ttagcatcta gcacctgatc
    10321 atcaggtaat ttagcgacaa catgatctat caaggcaata gtagactcat cacttgtgac
    10381 ctcaaccttg tcaatacctg tttcaatttt gctaatctca tagcccttag ccagctgctt
    10441 actatcgacg ctgccacgca ccggaaaggt ctttgttttc ttatttccaa tcgttaccga
    10501 aatcttatca ggagaaacag ttgctgtcac accagtaggt agattgataa cctttagggt
    10561 caccgttgca gtacctggct tactctttgt tagatcagct acgatcttaa agcttctagt
    10621 gtcactgttt acctctgaat ccagctttat gcggttggta gaggtcagat aaacctctgc
    10681 accgtaagaa tagccgctga tgaagtactg atcactatca tacttgatat caataggaac
    10741 gtcctttaag ctatgggtgt aggtttcaat agggctataa atttgagaat tagaatgatt
    10801 atgactgcta gaagcagcgg tcaaaaaaag aataatcgca aaaaagattg acactaagcc
    10861 cagcccaaga cgactattta aaaacctctt catttagctt tgcctcctaa gattttttta
    10921 taccaaggta atgtcgcacc gggctcattc atcaaatgag tcttgagaac cgcctcaagc
    10981 tcttctgttg aaaggtcgtg taaaaattga cccttacgag cgatagagac agctcctgtc
    11041 tcctcagaaa caattatcgt tacagcatca gaattttctg aaagtccaat tgctgctctg
    11101 tgacgtgttc caaattcttt ggaaatcgac attgattcag acaaggggag ataagcacag
    11161 gctgcagcaa ttttattgtt agccacaatg accgcaccat catgcagcgg tgtgtttggg
    11221 ataaagatat tgatcaatag ctgactagaa atatcagcat ttaggggaat tcctgttgcg
    11281 atatattcct gcaaggtctg cgtttgctca atagcaatca gagcaccaat cttccgcggt
    11341 cccatataag caactgattt taagagcgca tcaaccagca tctcctcatc actcaagctt
    11401 tgcttttgca aaaatacctg tgttgatcgg ccaaattttt caagccccgc tcgaatttcc
    11461 ggagcaaaaa tcaccacacc tgcaatcact ccataggtga tgacctgatt catcagatag
    11521 gttatagtcg taaaccctat ccactcggca atcacacgaa tgatgataaa gaatataacc
    11581 ccttgtacca aggacatgat cttagttcct gccaaggatt taataaaacg gtaaatcaaa
    11641 taggctacta ttaaaatatc cagcaaatga accaccaaca tcaaggggtc atcaatcagg
    11701 cttagtaaaa attttgtgtc aatacttgat aaattactca tacaattctc atttctatgt
    11761 cagatagata cctctaacat tatatcacgt ttcaagatgt tttccctatc taaaatttaa
    11821 gaacttatgt taaaatatta acatgaaact aaagacacta ctcgctatag cagccggaag
    11881 gactgcgcag ctcattttaa ataaaatcgg aagaggctca acctaccccg gacgattggc
    11941 cttgatgtgg gataaggata ttttagacac acttgccaag gactatgaga ttgttgttgt
    12001 gacagggaca aatgggaaaa ccttaaccac agctctaact gttggtatcc taaaagaagc
    12061 ctttggtgag gttttgacta atccaagtgg cgccaacatg atgacaggga ttacctctgc
    12121 ctttttatct gctaaaagaa aaaaaacagg caagcctatt gccgtcttag agattgatga
    12181 ggcaagcctt gcaagggtaa caacatacat taagccaagt ctttttgttt acactaatat
    12241 ctttcgagac cagatggatc gctacggtga gatttacacc acctatcaga tgattgttga
    12301 tggtgctagt caagcgccga aggcaaccat tctagctaac ggtgatagcc ctatctttgc
    12361 ctcaaaggac ctggttaatc ctgttaaata ttatggcttt gacacaccta agcatgagcc
    12421 acgcctagct cactacaaca ctgaaggcat tttgtgccca aaatgtgaac agattctccg
    12481 ttatcgtctc aacacctatg ctaatctagg agactatacc tgcttaaatt gtgatttcca
    12541 aaggcctaag ttggattaca agctaacgca attaaccagc attacccatc atagctcagc
    12601 ctttgtgatt gacgatcaga cttatcgcat aaatgttgga ggactctata acatctataa
    12661 tgccctcgca gctgttgctg ttgctgagtt ttttggcatt tctgctgatc agattaaggc
    12721 tggcttcaat aaaagcaagg ctgtttttgg tcgtcaggaa accttctcca tcaacggtaa
    12781 agcctgtacg ctggttctca ttaaaaaccc tgtgggtgct agtcaggcac tagaaatgct
    12841 gcgcctagcc gattatccct ttagcctatc tgtgctttta aatgctgatt atgctgacgg
    12901 tattgacaca agctggattt gggatgctga ttttgaattg attaatcaaa tggacattac
    12961 tgagatcaac gccggtgggg ttcggcattc tgaaattgca agacgcttac gagtgacagg
    13021 ctttgatgag gctaaaatca catcattcga taagcttgaa ggtatcatgc aagccattga
    13081 aaaccaagag gctgagcatg cctatatcct agcgacctat actgctatgc tagcatttcg
    13141 tgagctgctt gccagccgcc acattgtcga aaaggagatg atctaatgac ctatacctcg
    13201 ctacaatctc cggaaaatcg cgattatcaa tacgaccttc atattgctca cctttatggt
    13261 aatttgatga atacctatgg cgataacggc aatgtcttga tgttgaagta tgtcgctgaa
    13321 aagctaggcg ctaaggttag agttgatatt gtatccattg gggatacctt tgaccaagat
    13381 gattatgaca ttgttttctt tggtggtggt caagattatg agcaagccat tgttgctaga
    13441 gatttgccat caaaaaaaga ggccttagca gcctatattc accaaaataa ggtactcctt
    13501 gccatttgtg gtggctttca gctgctggga cagtactata ttcaagccaa tggccttaaa
    13561 atcaatggca ttggggttat gggacattat accttaaacc aagataataa ccgctttatc
    13621 ggaggcatta aaattcacaa tgatgacttt gacgaaacct actatggctt tgaaaatcat
    13681 caaggacgga cctttttatc tgacgatgaa aagcctcttg gacgtgtcat ttatggaaat
    13741 ggtaataata aagaggacca aactgagggc gtccactata aaaacgttta cggcagctac
    13801 tttcatggac caatcctttc gcgtaatgtc agcctggcct atcgcctagt cacaactgct
    13861 ctcaaagaaa aatatggctc gactgtttcc ttagcggcct atgataagat cttacagcat
    13921 gagacctcag aggaatacgc tgatgttaaa agcaaggcta gctttgacag ttaagtcctt
    13981 ctcatagcct gattaaacca caacagacat gcaaaacagt tattcccgaa tgaaaatata
    14041 gatttaaata gacaccctca atgtttttcc tatcataaaa tccataaaag ataagacata
    14101 ttcttgcaat aactgaacat tgaaagacag aaagctttct gtccttacta aacatctttc
    14161 atgcgtctgt cgtgctgatc aagcgagata accccaaaaa agtgctagca cagtaacaaa
    14221 atggctatga ccatatgtct gtgcagctct actgtcactg catagacagg ctagagggga
    14281 cgccctactt ggttcagcga tctaggggta ggtctagctt gtttgtgctg agtctgtttc
    14341 ggtagcaaag attgaatcct gctataagat actctcaaaa agattaaccc aaaagccttg
    14401 caacacattt aacgttttta gggataagta ccgatatgca gacacatagc aggagatcta
    14461 tgtgtctggt accaaaggac acaaaaaact aaagtaacac actaaaagcc acatgatacc
    14521 catttgatag ggggcgtcat gtggcttttt tctatctcac tgttcattac aaaaagccaa
    14581 accagcttct ttttgcatta ggcaacaatg gcctttgcca cctcttctac tgtcatacgt
    14641 gagaaatatt gtgttgtatc aatggtttga agacgctcaa gcacatcagc atactcgtat
    14701 ttgcaaccaa tgagtaggct ttcaatatcc tgcacgtcct taataccaaa gaaatcaccg
    14761 tagatcttaa gattcttaat aacagaattt tcaacattag caaaggttga gattttaccg
    14821 gcagggtagc gaacattacg ttcaatcgtg tattcaggtg cctttccata ggtccaatcc
    14881 cagctcccaa attgctcctc agccgattgt tgaatcttag ccagctcgtc ctctgacaag
    14941 acgtattctg tcatgtctgg ataggtctcc ttcattttaa ccaaaatctt gtctgaaaat
    15001 gcttctacgc tgattttttc tggcagctca tttaaaatat tggtcacgcg ggctcgtaca
    15061 gatttgactc ctttggactc aatcttatcc ttactgacct tgagcgcatc accaagaaca
    15121 gtcatatcca catcaaacaa gagacagcca tgatgcatca tacgtccctt ataataggct
    15181 tgagcattgc cacagatttt cttgccatca atttcaatgt cattgcgacc tgtaaaatta
    15241 gccttaactc ctaaatcagc caaggtctca ataactggct gtgagaaggt tttaaaatca
    15301 aaggctcctt ctgttgtttt attggaaata atcgtgtagt taaggttatt gagatcatgg
    15361 taaactgcac caccgccaga caagcgacga accacatgaa taccatgctg ttcgatgtac
    15421 tccttgttga tttcctgaat ggtattttga tgcttaccaa taataatagc cggctcattg
    15481 atccagagga taaacaattc atcctcatca accaattctc taaaggcata agcctctaga
    15541 gcaatgttaa aggcagggtt gtggctctta ttaacaatgt atttcatttc tatctcctat
    15601 agcgataatc gttatcatat tctattcttt attctaatgg aaactcttac aaaagacaag
    15661 ctaaaagagg ctagcaaaag caagggaact agtaaatgct tcctcaatca agaaccatct
    15721 gcaagctagc agtaaagctt gatctaactt aaagagcctt ccttgtatca acgaaagagc
    15781 tgagaaatct ttttcccagc ccttttttat cgcagctata tagctagctt attttttacg
    15841 ttttggtggg ttatgaatgg cttcgccaag cacatctgca aaggcttcgt acatcacctc
    15901 tgagaaggtt gggtgtccat gaattgacaa tagcaattca tcaactgtta gctcagcctc
    15961 catgattgtg gctgcttcat tgatcatttc agcggctgct ggaccaatga tgtgaacacc
    16021 aagtatttca tggtatttag catctgcaat aacctttaca aagccatgag cctcgtttga
    16081 cgcaatagca cgaccatttc ctgtaaagct atttttacca ataagaacat cgccatattg
    16141 ctcacgagcc tgctcttcag ttaaaccaac catagcgacc tcagggtgag tatagaccgc
    16201 cgctggagtg tattttaggt tagccttacg tgttgtgctg ccatgcatgg cattctcagc
    16261 agccacctca cccatacggt aagcagcgtg ggcaagcatt ttagtgccgt taacatcacc
    16321 cggtgcataa atgcctggga ttgacgtttc ttggtagtca ttaaccttaa tgcggttacg
    16381 gtccatttca aggttgaggt tttcaagacc attcatctgt ggcacacgtc caatagatag
    16441 caaggccttt tcagcaacaa cctcttcgcc attattaagc ttcaaggtca actggttgtt
    16501 ggcttcaaca atctcagaga caccaactga ggtctttatt gtcatgcctt tcttagaaag
    16561 gattttttga agctccagtg aaacctcctt gtccatggca ggaataatgc ggtcagccat
    16621 ttcaataact gtaacctcta caccgtaaga ggcccaaaca agaccaagct caataccaac
    16681 aacaccaccg cccataacag caagtgattt cggcatttca cgcaaatcaa gaatatcatc
    16741 agatgtcaag acaagcttag aatcaatccc tggaatattg atgcgtgaga ccttagagcc
    16801 tgtcgcaaga ataatattgc gccctttaat ggtttgcaca ccaatggtaa ccgttttatc
    16861 aggatttacc tgaccaaggc cattaaagat ggttaccttg ttggctttaa gaagcccttg
    16921 aaccccacct gttagcgtct taacaaccgt atttttaaag tcaactgtct tatccatgtc
    16981 aatagtatag ttggttgaag caaggttaat cccgcgtcct gctgcaatct tgatgccatc
    17041 aaggatttca gcatttttga ggtaggtttt tgttgggata cagccaacgt ttaagcaggt
    17101 accgccaaat tcagattttt caacgatagc aatcttgccg cccagctgag caccacgaat
    17161 agcagcgtag taacccgcag gaccgccacc gacaacaatg atgtcatatt catcagcagc
    17221 aagctctgcc tttggtgctg atggcgctga tccttgatcc ggtgcctttg gcacctcaag
    17281 accagccgcc tgtaaatcct cggttgtacg cgcaacattg acatcagccg ctgctgggct
    17341 tgatacatcg atagcttcac ccgcagctcc aatgtagccg ataacttcgg ttacagggac
    17401 tgtctcacct gcctggcgaa tgatttttaa aagcacacct gagtcttctg cttctaattc
    17461 catattggtc ttgtctgaca tgatttccag aagaatgtca ccctcgctga cagtgtcacc
    17521 ctcctgcttt ttccactcga tgatctcgcc ttcttgcatg tcaacaccga gctttggcat
    17581 aataatttca acagccataa tgatattgta aggaacgttc aaatgcaatc agatgcctta
    17641 acaatcagca ctggctaaca taagcctgct aaaagccctg catttagctc atagctagtg
    17701 actacgagct cgttccagat cctttctata gttttaaaga attatctttt cgttactttg
    17761 tttctgaaat atgctctctt tgcatcgcag gccataaggc ctgtcatcag attagcagtt
    17821 caaatggatt ttccatcaat tttttgagat caaccatgaa tttagcacca ttcatgccgt
    17881 ccaccagacg gtggtcaatt gtcagacaca ttgccatgat tggacgtgca acaatctcac
    17941 catcgaccac tgttggggtt ggaatggttg ccccaatacc tagaatagct gaattaggct
    18001 gattgataat tggattgaag gttttggtgc caaacatacc cagatttgtg atggagaagg
    18061 ttgagcctga catttcggta gcctttagct tgcctccttg agcctttttg ataacgtcct
    18121 tagaagcaag gacaaactct gagagactca tcttatctgc accatgaaca actggcacaa
    18181 ctagcccatc atcaagtcct acagcaatac caaggttgac aaagcgatga agctcaatat
    18241 cattagcatc attaatcaat gacgcattca tgtattcgtg ctctggcttc atcaaggtct
    18301 taacaacggc taaaccaatc aagtcagtaa agctaacctt tagccctgtt ttagccatga
    18361 ttgggtcaat cagcttcttg cgcaaggcaa tcatttcggt catgtcaatg tcataattaa
    18421 gcgtaaaggt tggtgctgta aggtaggaat gtgtcatacc ctttgaaata gccttacgca
    18481 tagcagacat cttcttaatt tcaacaccct ctggaagctc cttagcaggc ttttcttcag
    18541 caatagatgc tttttccaca gcaggtgctg ctgcgccaag cacagccaaa atgtcctcct
    18601 tggtaatctt gccaccaata cctgttccga ccaccgctgc aaggtcaact cccttgtcgg
    18661 cagctatctt acgagcaagt ggcgttgcct taggctgagc tcctttgaag ccttcaacgt
    18721 cttctttgtg gatacggccc tttggtcctg ttcctggcac ttggttaagc tcaattccca
    18781 tttctgaagc tgctttacga gctgctggcg ttgcgcgtac cttttctccg aaggctggag
    18841 cattggcaac tgatgctacc tgaggcgctg ttgaggctgc ttctttcggt acagttgttg
    18901 tattagcttc tgctgatgtt ggtactggaa tttcagttgt tttctcactt gaagcagtac
    18961 tattatcaac agattcacct gcagcaccaa tatagccgat aacctcagtg acagggactg
    19021 tttcacctgc ctggcgagtg atttttagaa gcacacctga atcctctgct tcaagctcca
    19081 tatttgtctt gtctgacatg atttcaagaa gaatgtcacc ctcgctaaca gtgtcaccct
    19141 cctgcttttt ccactcgatg atctcgcctt cttgcatgtc aacaccgagc tttggcataa
    19201 taatttcgac agccatatat ttcctttcat ttaatcccgc agcccatgat cttaagacca
    19261 gatacagctg ctgaaaaaag ggatactgtt ttatcagcct gatgaagaaa gcctctaagc
    19321 taagacttcc tttgccatgc taatttccct tgttgaccat ttttacaata gcagccttga
    19381 ttttagcaac atctggtaag atagcttgct caagaacacg tgcataaggt actggtacgt
    19441 cctcactagc aagacgcaca attgggtgat caaggtaatc aaaggcttca ctttcagtga
    19501 ccattgctgc aatctcaccg ataaagccac cagtcttata ggcatcatta acaagcataa
    19561 gcttccctgt cttcttaaca gaattaataa ttaattcctt atctagtggg ataagggtac
    19621 gtggatcaac aacctccaca ttaataccat cagctgcaag ctcttcggct gcctgaagga
    19681 cacgctctag catacgccca taggaaacaa tggttacatc agtcccttca cgcttgatat
    19741 cccccttgcc aagtgggata taaaaatctg gatcctgatt gacctcttct tttttaccgt
    19801 acaaggcctt aggctccatg aaaataacaa tattgttatc acgaatagct gactttaaaa
    19861 gtccctttgc ttcgttagca gttccaggtg caaccacctt gatcccagga atatgcgtca
    19921 accaagcctc aagagattgc gaatgctgag ctgcagatcc aattcctgag ccagaagcaa
    19981 cacgaaaagt tgctggcgtg atcaagccac caccaaacat gtagttgttt tttgccccat
    20041 tattaacaat tgcatcaagt gcaatggtaa taaagtccat aaaagtaagg tcaacaatcg
    20101 gacgaagccc tgtaattgct gaaccaatcg ctgcacctgc aatagcagcc tctgaaatcg
    20161 gcgtatcctt gacacgtttg gcaccaaatt cctcaatcat gccaacagaa gtaccaaagt
    20221 ctcctccgta aacacctacg tcctcaccca taaggtaaat cgtgtcatct ttgcgcatct
    20281 cctctgtcat ggcaagattg atagcctcac gcaaagccat taattttgtt tctgtcatta
    20341 ttatctccta atgtttacaa aatagaattg tcaatgttac tgtgaataga tttttgctcg
    20401 atgtgctagc agatcagcta gtctacccaa acgtcctcaa aggctacaga aatgtctgga
    20461 tctggactat tttgtgcaaa ctcataagcg tcatcaattt cttgcttgac ctgtgcttga
    20521 agcgcatcta attcttcatc tgtagcaatg ccttcacctg ttaggtaagc gcgatactta
    20581 agcattgggt ccttttcctt ccactcatca acctcttctt tggtgcggta tttgccggca
    20641 tcagcagttg aatgaccaaa ccaacggtaa gactcaacct caacaacagc aggaccattg
    20701 ccaccgcgaa catgctcaac agccttactc atggtttcat aaactgccat cacatcgttg
    20761 ccgtcctcac aataaaagcc tggaatacca taagcctcag cacgcgtgta gaggtgaggt
    20821 gtatttgtgg cattgttaat gctcatggaa atcccatagc ggttgttaat gataaagaaa
    20881 atcacaggaa gcttccaagt tgctgccata ttgacagact catggaagga gccctcattt
    20941 gttgcgccat ctccagaaaa ggccacaacg atattgttgg tccccttgta ttgctgtgtc
    21001 aaggcagcac ctaccgcaag ggcatagcca cctccaacga taccatttgt tccatagttt
    21061 cctttttcaa aatcagccaa gtgcattgag ccgccgcgtc cctttgacac acctgttacc
    21121 ttaccggcta gctcagccat cattttattg aggtccatat ctttagcaat agattgccca
    21181 tgcccgcggt ggtttgaaaa aataatatca tcataggtca aatgtgccac agcgccaacg
    21241 tttgctgcct cctcaccaac tgagaagtgt gtcatgccct gcacaaatcc acgacggaca
    21301 agcttattaa tacgtgaatc aaattcacga atacgctcca ttttaaggaa catatctaaa
    21361 tgttgttctt tagaaactgt taccatttcg gcctccatat tatcatatta cttcctaatc
    21421 ataaaacttt tcttcacaat ttgcaaggat tttaatcgct ttctttgtga ctataaaagc
    21481 ttttttaaga cgttttagtt tgtggtttca caagctagat tgttatagca tctgttacat
    21541 ttatatataa cagattgaaa aatgagtcag tgtttattca gggaggtcaa gcacctattg
    21601 actttgatag tcagaaatat catcactctt taagaggaaa ataggctcta aatgacctgt
    21661 ttcttctagc acaatcatga tcacctacca aacgaacgct ttgcttgcct cgctccgata
    21721 gaggcgaaat gaactaaaaa tcgcataact aaaaatgcct gattttacct gaaaatcaga
    21781 catttaaaag ctttaagaca ttagactcag gctctaatta taatcctcta agaaaagcct
    21841 gctaccttgc actacccaag aatagcaagg caatttcatt atctcaccag gctactccag
    21901 ctgtcctgca atgtcctccc actccagcag caaggtctcc tgtttctgat taagctgatc
    21961 caactctttt tgccagtcta tcagttgagt cgtatcattt gatactagca tttgagcttc
    22021 tatagcctta gcctgtgctt ctagcccttc taaggtctgc tcaatctcct caaagcgcct
    22081 tgttaagcga cggtattcct tttggctggc cttttgaagc tgataatcag ttacagcagc
    22141 ttctgctaca tcagtctcta ctacgtgatc tgcagcagct agacgggcta attcctcccg
    22201 ctctgccttt ttttctacat aatagtcgta gtcccccaga tagagtgttg agcctgcttc
    22261 agttatttct aaaaccttag tggccactcg gttgataaaa tacctgtcat gactaacaaa
    22321 caacaaggtc ccatcaaagt caatcaaggc attttctaga acctctttgc tatcaatatc
    22381 caggtggttg gttggctcat ctagaatcag aaaattgtcc tttttcatag ataattttgt
    22441 taagagcagc cgagcctttt cgcccccaga tagcatggcc acagactttt tgacgtcctc
    22501 accagaaaag agaaaggcac ctaagcggct gcggatctca agctcagctg tcgttgggaa
    22561 atcacgccaa agctcctcca atacagaatt actaccagtc agatgagatt gcgtttggtc
    22621 ataatagcct gtttcaacat tagtcccata atggcatgtc cctttaatca aaggaatctc
    22681 tccaataatg gatttgagta gggttgactt gccaatacca tttggcccaa caatagcgat
    22741 tgcatctaac ctacggacat ctagatgaat tggctcagct aaaatatggt cattgtagcc
    22801 aatagcggcg tctgtcacct gcaaaacaac atttcctgag ggcttatcaa tctgaaaagt
    22861 catactagct gatttgcgag agctacttgg cttgtctaag cgttctagct tttctagctg
    22921 cttgcgtctt gcctgagcac gcttggtcgt tgacgctcga acaatgtttt tttggacaaa
    22981 atcctctagc ttagcaatct ctttttgctg cttgtcataa tgcttctctt ctgctgcaag
    23041 cttttcagcc tttaaatcaa taaagcgtga gtaattacca acatagcggt ctaagctatt
    23101 tttagtcaga tcaagtgtga tggttgcgac cttatccaag aaatagcggt catgactgac
    23161 aatgatcaag gctccctgat aatttaccag ataatgctcc agccaggcaa tggtttcaat
    23221 atctaaatgg ttggtcggct catcaagcac caatagctct ggcttttcta gtagcatttt
    23281 tgccagggcc aaacgggtat tttgcccacc agaaagctct gagattttca tttcccacat
    23341 gctttcgtca aacttaaagc catttaaaat agctcgaata tctgactcat aggtgaagcc
    23401 atttcgcaag cgaaagcttt ctgacagccg gtcatagtct gacatgagct ggtccagagc
    23461 ttgccctgat cgactggcca tatcagcctc catttgcctt agtcgctgct catcaaccct
    23521 caattcagca aataccttta gcatttcctg ataaatggtc ttgtcagact caaatcggct
    23581 attttgtgcc aaataagata gggttaagtc cctttttcga ctaacctcac cgctagttgg
    23641 ctcttcttct ccaactaaaa tcttaagaag ggttgatttg ccagcaccat ttggcccaac
    23701 caaggcaatg cgatcacgtt caccaacctg cagcgatagg ttttgaaaaa gcacctctcc
    23761 tgaaaaagag cgctcaatgt tatttccttg taatataatc atacccttat tgtagcaaaa
    23821 aaatgccctt ttggggggca cttttagtta tttttacagg taagataaga ctcatcaaca
    23881 agctaaagac ataagcctta ggctaacatc gcttatcacc cttagtggta tttatctgat
    23941 gagacaaact gctgcttgaa aaaccagtgg gttgacctgt tagcgtatcc aacaatcgca
    24001 ccacctgctc agttatgctt gaaatgctat tagccagtga ggaatcacta tggttcgaat
    24061 aataaatcaa accaaaaata agcaatacca atactattag ggtctgcaaa cagcctctga
    24121 caagctgcca gacaagcttc agcagaagct ttgggaggca taagaggata gtcagtagtt
    24181 ttttcatcgt aataagccta aattctttcg tttaggatag cctttcttcc ttgtggtaag
    24241 caatcggcag ccaatctaat agggcctcta gctgctgatt ccaataatac cattcgtgcc
    24301 tgccatgatc cttacgataa tcaatagtca agccaagcct tctcaactca gcaactgcct
    24361 tttcattggc ttcaaacaaa aagtcctcat agccacacca agcgtatagc tgggtttgac
    24421 catcactttc tgctgctata cttgtcaaat aatgcttttt gatatcagga gcattcaaat
    24481 ctccaaaaac accctgccaa taaggcagct cacctatacc ttgctgtaat agcatttccg
    24541 gcgaaaaatg caaggcccca gaaaaggaag cagcatagga aaagcgattg ctttttaagg
    24601 cccatttaaa ggcaccatag cctcccattg acagcccagc aacaaaggtt ttttcacgct
    24661 tagtggtcat attaggaaag aaagaagcta atagccgagg aagttcctct gcaatagctt
    24721 ggtaataatt cataccgtag gtggtatcgg tataccagcc taaatcagtc gatggcatca
    24781 ccacgattaa attggtatgg cgaagcagcc tttcaatatt agtccgcttt tgccaggaat
    24841 tttcatttcc tcccatacca tgtaacagat aaagaactgg aatatcttgg tagccttgct
    24901 cttctgggct aagctcagac tgatcagggt agatcacctt gacatgtctt tccatagcca
    24961 agatctctga atgatactca atgctaatgc ttgccatcag ctcacctcct ttttaatatc
    25021 accaaagcat aaggaaagcc cactcttaag acctaaaagc cagatcctat ttgaccagct
    25081 tttaggcagg gctgtatctg tattaacgga cctccataac aaccggaaga atagctggcc
    25141 gacgcttggt ctgctcaaat aaaaaccttg agagctcctc tctaacagag cctttcaatt
    25201 cactccaatc aaaatgatcc ccttgcagat aattgccaac tgttgtgttg accaattcag
    25261 cactttctcg taaaatatct ctgctctttt tcacatagac aaatccgcga gtgttgacct
    25321 tagccttaga gataatacgt ttttcctttt tagatactgt gatcgcaaca ataaaaatac
    25381 cgtcctctga taagacctta cggtctctca aaacaatatt gccaacatca ccaatggcat
    25441 ttccatcaat catcacatca ctagcaggaa ccgcaccctc gtgtaagaag ccatcctcat
    25501 caagcaccat gatgtcacca cgcttcataa tatgaatatt ttcaggtagt ataccagcct
    25561 cctcagctaa atgagcatga gcagctagat cgcggtattc accttgaatc gggaacaggt
    25621 attttggttt gacgagatta atcatcagct gcaggtcacg cgcattggca tgtccagaaa
    25681 cacgtaaatg ctgcgtgatg agcttaacag agccacctgc tttatagata aggttttcaa
    25741 cacgagcaac cattgcttcc ttggcagcgc ttggcgttgt gacaatgtaa accagatctc
    25801 cgtccttgat ttgcacgtgg cgatgacgcc ctattgccat tttctgtagg ctattaatcg
    25861 gctcacccat acgtccagcc tccagaacaa tcaattcgtg atcctcaaac ttagacatat
    25921 cctttggctt gattaatagc ttttcatcag caatcactag ctttttaaga cgaagtgctg
    25981 ttctgacaat attttcagcg tcagtacctg tcagtaccac tcgcctgcta taggctgctg
    26041 cagaatcaaa gacctgctgg atacgaacaa gatttgaagc gacagctgca atgataatcc
    26101 gcccgtcggc atgagcaatc accttatcca tctcctcgcc aacctcagct tcgctggcag
    26161 tctgctcatt gcttgtggca ttggccgagt cagctaatag ggctaacacc ccttcttttc
    26221 caatgtctgc caagcgagct aggtctgtct gatagccctc acgcgaagcc tggtcaaact
    26281 tgaaatcacc tgtatagaca atattcccct tatcggttcc aataaccacg cctaaacttt
    26341 caggaataga atgtgttgtc ttaaagaagg aaaccaagcc atctttaaat tcaatttctg
    26401 tgtcactgtc gaccacatgg aaattcttaa atctcttggt gctattattg gccttgacaa
    26461 acaattttgc tagctcgatg gtcaattctg aaccaaatac tggcactgga acctccgcca
    26521 acaggtaagg caaagctccg atagcatcag catgcccatg acttaaaaag actccctgaa
    26581 ccttgtcctt gttttcaatt acataatcaa gacttggaat taccaaatct acacctagct
    26641 gttctgtttc agggtatttc aagccagcat ccaaaatgaa catggaatcg ttaatctcta
    26701 ctagatagaa gtttttcccg tactcacgta cgcctcctaa tgcaataatg tttatatcag
    26761 tcatgatact ccttttttta tattagttat tacaaacggt ccttactggg taagtcgaat
    26821 tactgtcttg cagctaagct gcactctttt acagtatatc atattttagg gcttattacc
    26881 tcaaattgcc ttgagacttt ctcaatcttt tcaatagatt atcaaaaaag ccaagggaag
    26941 gctttcattc caatggcttt tagagtattt attttagtca aaaagctggt aataatcagc
    27001 aatggtcatt tgagattttc tcttctgatc aaggtcttga atgattttac catttttcat
    27061 cacaatcagg cgattaccat agttaagagc gtcctccatg tgatgcgtta tcattaaggc
    27121 tgtcaagcga tccttagcta caaaatcatc agtcaaggcc attaaggctt ggctggtctt
    27181 agggtctagc gctgcagtat gctcatctaa tagtaaaagc tctggtcttt ttagggttgc
    27241 catgagtaag ctaagggcct gtctttgacc gcctgataag agaccagtcg gagtctccag
    27301 atgattttcc aagccatttc caactcgctt gaccaagtca gcaaagtctg ccatataatg
    27361 gctaatcctg cgtgatgaca agcctcgcct ttcccctctt tgccttgcaa tcaaaaggtt
    27421 ttcagctact gtcattcgag gtgctgttcc cattttagga tcctgaaaaa cacgtgatag
    27481 gtagctagct cttttttctg ctggcaggtg cgtcacatca tgccctaaaa gcttaatttg
    27541 acccttgctt aacaatagcg tcccagcaat cacattaaaa agggttgatt taccagcgcc
    27601 attcccacca agaatcgtta aaaaatcatg ctcataaatg gtcaaggaaa catcatctaa
    27661 aatagcctta gtctcatcaa agccattatt gacttcgaca gtagcgtgaa ttaattcaat
    27721 aatttttctc atcgtgataa gctagcctcc ttaataattg ctttttttag cacaggcacc
    27781 atcaggcaaa gtgctaatat aatggcacta aatagcttaa gataatttgt attaaagcca
    27841 agagcaataa ctactgagat taaaaattga tacaggatag aaccaaccac aatggctatc
    27901 aagcgctcaa gcagggttag gcctgtagaa tataaaacct caccaacaat aatactcgca
    27961 aggccaatta caatcacacc aatccccttt gaaacatcag catagccatc ttgctgacta
    28021 accaaggcac cagataaggc tatcaaggca ttagagatcg ctaagcccat aagctccata
    28081 cgatcagtat gaatcccaaa gctcttagcc atatcccgat tatctcctgt ggcaatataa
    28141 gcctgaccaa tattggtgta aagaaaatac attaacaaaa aaatcaccaa tgtagctaca
    28201 accaaaccag ctaccaacac attggtgtca gctgcaaagg gaaggtagtc ctgaatgcgc
    28261 ttgatatcat gcaagcccaa attggccctg cccataacca taagcataat ggaatggcag
    28321 gaggtcatga ctagtatgcc ggcaagaagt gttggtatct ttccttttgt gtataacagg
    28381 cctgtggcga agcctgccaa ggcacccgcc agcatagcag ccagagtagc caggatagga
    28441 tttaaaccga gattgagcag agttactgct acagcacctc ctaaaggaaa ggacccttct
    28501 gttgtcatat ctgggaaatt caatattcta aaggtcaggt aaatccccaa gccaagaatt
    28561 ccccataaca agccttgtga tacagatgaa ataatcatat gaactccttt tctattgctt
    28621 acctgtaagg tcagaacgct tcagcaggtc ttttgagatc ataagaccta aatcccttgc
    28681 tgcctttaga tttaaaaatg gcttaccgtc atcaactacc tcgacaggaa cctctgatac
    28741 ctcttttcca gccataagct gcagcacctg cctagctgtc tcaaccccta attggtattg
    28801 actttgtgaa atagaagcaa gactcccttg ctcaaccatt gtatcaacac ttgagtagac
    28861 cggaagctgt gctgcatttg aggcaacaat caccgctgaa aaagcactgg caatagtatt
    28921 atcctgtggg ataaaaacag catctacctt ctcagtcatc acagacatgg tcgtggtaac
    28981 ctcatttgtt gaggggacag cgtaagctag aacctccaag ccttgctttt ctgcaagagc
    29041 tgtaaagtcc ttgacctgtg atattgaatt gtcctcactg cttgcataaa ggacaccgac
    29101 ccttttgacc tgaggggtca tctccttgat cagatcaacc gtctgtcgaa caggaacctt
    29161 atttgataag ccagtaacat ttgcctcagg cctgtctaag tgcttgacta atttagcacc
    29221 aactggatca gaaatagctg acatcacaac cgggatagtc ttggttgctg ctgctaatcc
    29281 ttgagctgca ggcgttgcga tgccaacaac aatatcgttt gttttgacca gctgcttgct
    29341 catggtctga atcttacttt gatctccttc tgcattcata agggtaatgc tgaccttttg
    29401 ctctggctga tgatgcttct ttagctcgtc tttaatgccc tgtgcaatct ggtcaagcgc
    29461 ctcatgagta accagctgca atataccaac cttaaccaca cgcttgctgg ctaactgtgg
    29521 ctgttttttg ccctctttta gcactagcga agcagcaacc attaaaaaga gtgcaatgac
    29581 tgttacgata agacctttat gtttcatgtt ctacctctta atttccattc ttactccgtt
    29641 gctaacattt agagtactca caaaaagaaa aaacgcttag taatcagcta ctaggcgctt
    29701 tttttgaaat ccaatgtcag cgcatagata cctttttaga agtactctaa aagtcgtatc
    29761 tatgctaacc cataaacaca actttatcta tgccagcttt gccaatttat catatgctgt
    29821 gtttgcttca tcttggattt cctttcttgt ttttttacat tataacctaa aagctcaaaa
    29881 atacaagagc atttgaacat atttttccat tattttttgt ggtataatga aagaattaga
    29941 actcaggagg gagaaaccat gtcatttgac ggctttttct tacatcattt aactcaagag
    30001 ctcaaccata gtattgttaa tgggcgcatt caaaaagtca atcaaccctt tgataatgag
    30061 ttggttctga ctatccgtaa ccatcgccaa acttacaagc tcttgctctc agctcatccg
    30121 gtttttggac gcattcaact gacccaaaca gactttcaaa atcctcaatt tcccaatacc
    30181 tttaccatga tcatgcgcaa ataccttcaa ggagctatca ttgaaggctt tgagcagatt
    30241 gataatgacc gcatcatcga aatgaccgtc tctaacaaaa atgagattgg cgatgccata
    30301 aagacgacat tgatcatcga aattatgggc aagcacagca atattattct ggttgaccgt
    30361 catgaaaaca aaattatcga gtctatcaag cacgtcggct tttcccaaaa ttcctaccgg
    30421 actattttac caggatcagc ctatatcgag cctccgaaaa caactgctgt caatcctttt
    30481 acgatctcag atatcgcttt atttgaagtc ctgcaaacac aggagttatc tgctaaaaat
    30541 cttcaaaagc atttccaagg gcttggccga gataccgcac aagagctatc cagtctcctg
    30601 acaactgata agctaaaacg gtttagagac ttttttcaaa gacctagtca gccaagtcta
    30661 actcagacct cctttgctcc agttgccttc tcaaacacac tgaagacctt ccagaatcta
    30721 tctcagctgc tagattatta ttatcatgac aaggctgaga gagatcgtat caaccagcag
    30781 gccagtgacc tgatccaccg cgttcaaaac gaattggaaa aaaatcgcag caaactgatt
    30841 aagcaagagg ctgagctgct agccactgaa aatgcggagg actttcgcca aaagggtgag
    30901 ctcttaacaa cctatctgag cctggtgcca aatgaccagg attcagttga gcttgataac
    30961 tactataccg gccaaaaaat aaccattgca cttgataagg cgttgactcc caatcaaaat
    31021 gcccaacgct attttaaaaa atatcaaaaa ttaaaagaag ctgtcaagca cctctcaggt
    31081 ctcatcgctg acacgcaaca aaccatcgct tattttgaaa gcgttgatta caatctatct
    31141 caggcaacga ttgatgaaat tgaggacatt cgagaagagc ttattcaggc tggctttgtg
    31201 aaaagccgta agcataacaa gcaccacaaa cgtaaaaagc cagagcaata cctggcttca
    31261 gatggcaaaa caattattat ggtcggacgt aacaatctgc aaaatgagga attaaccttt
    31321 aaaatggcca aaaaaggcga gctctggttt catgctaagg atattcccgg cagccatgtg
    31381 atcattaagg acaatctaag cccaagcgac gaggtcaaaa ctgatgctgc tgaattggcg
    31441 gcctattatt ctaaagcaag actttccaat ctcgttcagg tggacatgat tgaagccaaa
    31501 aagctgcaca agccaagtgg tgcaaagcct ggctttgtca cctatacagg acaaaagaca
    31561 ctaagagtga cacctataga aagcaagatt caagccatga agtgctcccc ttcagcctct
    31621 tcctcatagg actacagcaa taaagataaa aaaagctaca gcctcacact tggagatagg
    31681 tccagtctta aagctgcggc ttttttatca ttacttgtta atcatctctc aaatcatcta
    31741 agaagccttg catatgaata tcatctggaa cctgctgcaa ataccttttt gcctgcttaa
    31801 ctgcttgatc agtatagccg aattccctta ataaataagc ataatcctgt aaaaagtcag
    31861 gattttcttt taggtctcct tcgatatctt tatagatagt gagggctttt tcttgctgct
    31921 ccagagcctg ataggccttg gcaagattcc atttagttag cacatgatca atctcctcat
    31981 gctcaagagc aatgacctcc tcaaaacgct ccatatccaa gtacaggcta gataagcgca
    32041 tgatgacctc ttcgtcatca acagctactt ccttggccct gagcaaatac cgctctgagc
    32101 cagctggatc atgcaattca aaggcaagct gtgaagcaag caacagcagc tgggggtcaa
    32161 aggcattttt acgcagaccc tgctgaacta ggcgtaaggc ctcttctgtc cgatgctcct
    32221 cacgcaagct catggcatag gggtactcgt agcctaaaaa gtctgcattc atcgtttcta
    32281 attgcttgaa atagagattg gccttttggt aagcagcctg atcatataaa atcgtcgcca
    32341 gctcaaacac tgtctcatcg tcatactcaa tggcaagagc cttttcaaga aactctacag
    32401 cagcttcaaa tttccctaaa taagcatagg cacgccctat gcgctggtag gttgagatac
    32461 ctgtcagctc aagaatgtga cgattatcaa gcctagcata ttgctcaata gcctcgctaa
    32521 agtgctccag agacatctcg atttcggcta agccaaagat cactatcggc tcctgactca
    32581 attcagctgc ttgaagtagc ttctcacgcg ccacatcagt tagcccctcc aaatcataaa
    32641 gatcagccat gacgagcaga gcagacaaat aatcagcact atcctctgga atcctatcaa
    32701 ggtacataaa ggcctcttca atgacattat cctcagctgc aatctgagca agattaatat
    32761 tgacctccgg ataagcctca cagacctgca aataaatcgt cttagcatgc agtaaaaaac
    32821 caatactctc taggtattct gccaaagcca acaaggtctc agcatcgtcc tcctgcaagg
    32881 ctctttgaaa atagctttct gcctgctcta aatcctgttg ctctagtgag gcaatcattt
    32941 tttcactatt taacatcttc agcgaccctc tcagcttctg taggctcttc ctcatacagg
    33001 cctgtaatat ccttgtacca atcaaatagc tccttcacaa caaccttaac agaagcataa
    33061 actggaatga caagaaagac accccagacc ccaaacattg accctgctgt caataataaa
    33121 aacataatgg taatcgggtg aatgctcagc ttatttccaa gcactagcgg cgcgacaaaa
    33181 cgtccttcaa tcgtttgttc aataacaaaa ataatcaaca ccttgatcag catcaagggt
    33241 ccttgcacca ttcccataat cactacagga atcatggcta aaaagctccc cagataagga
    33301 atcatattaa gaaagcctgc aataatacca aaggtaatag aatagttcaa accaacaagg
    33361 ctaaacatca ctgaaaacat gagaccaacc acaatcgcaa cggtcacctg tccctgcaca
    33421 tagccagata attgcttgtt gatttctcct aagacacgtg ccataggctg gcgcagctta
    33481 atcggaagca cattgaccaa accatttttc atatggccac tgtcacgcag aaaataaaag
    33541 agaataaaag gtgacatgat gattgcaaca gtaatacggg caatagctcc agcaaaattt
    33601 cctgcccaat caatagcatt tttagagaag ctttgcgcat aatctagagc cttttggctc
    33661 atactagtca gcatatcctg caggttggac ctgtagctaa ccagccattc gttttcaagt
    33721 agcttattag cctctagatt gaccttggca acatatttgg gaaggtcttc gacaaagctc
    33781 cttagctggt cttgaatcat agggataaag ccagaaatag cccagaaaaa taggagaatt
    33841 actaagccaa agacaataaa aatagaggct gtgcgatttg gacctagctt ctcaaccata
    33901 tcaactaatg gcttggtcaa ataatacagg atagttgaga taaccagcgg cagcatgata
    33961 atggccaaaa atgacaagat cggtgtaaag aggaaggata tttttgtaaa gacaaaaata
    34021 gtcagaaaaa ccagcagcgt gattaacaaa accatcaccg cctgattatt taaaaaccat
    34081 ttgtaaaata gactatcatg atgattaggc ttagaatgca atgacattaa tggtatcgtc
    34141 ctttcttaat tgtggcatca ttctgatgag agcttttagg ttagttgact taataaaagg
    34201 tgactgtttt ttccactagc ttgttgtggt catcatacct aaatttagca gaaaaaaacg
    34261 gccggtcttc cagtatccac ttgaaaatgt cgtaatctcc ctcccaggtt ggcttttcca
    34321 gcacctgatc atagggaacc cattctaggg tcccttctct ggactcctca tcagcaatta
    34381 agtcaccttc aaagtctgtc accttaaaca cgtaagtata ccaatcatgc cctggtgtaa
    34441 aatcaggaaa ggtaatcact cccttaaagt ccattgcttt taccagcagg tgagtttcct
    34501 ctaaaatttc acgtctggca cagtcatcag gagattcgcc tggctctaat ttgccaccaa
    34561 ctgaaatcca cttaccttgg tgaacatcat tttccttctt gttgcgatgc agcagcaata
    34621 aagcctcacc gttatcaata taacaaatcg ttgctaactt agtcattcat acccttcctt
    34681 tgtttagttg ttactattat accaatctct gagaaatatg ccatcatttt atcatttaag
    34741 cacatcaaac aagaaaacca caatcactac aactcttagc cctgtactag caaaaaagcc
    34801 ttgataaggc aacgtctgct gactcatcaa gacttatcac tatttaacga atcacttcct
    34861 gtgtcttagc gtaattggct tcaactgctt ctttttcgga acgccaccaa tcctgatgat
    34921 cagtatacca ttggatcgtt tgctcaagtc cttctgaaaa atcagtaaac tgtggctccc
    34981 agccaagctc ctgacgaagc tttgtcgaat caatagcata gcgtaaatcg tggcctgcac
    35041 gatccgttac atggtcataa gcgtccttag gctgccccat tttatccagg attaattcca
    35101 gcacttcctt attatttttt tcgccgtcag ctccaataag gtaggtctca ccaatacgtc
    35161 ccttggtcaa aatggcccaa acaccagttg agtggtcatt ggtgtgaatc cagtcacgaa
    35221 cattctttcc ttcaccatac aattttggct tgataccaga caagatatta gtgatctgac
    35281 gagggataaa tttctcgata tgctggtagg gaccataatt atttgaacag tttgaaatgg
    35341 ttgccttcac gccaaaggag cgaacccagg ccttaacaat caaatcagag gctgccttgg
    35401 ttgatgaata aggtgacgac ggattatagt tagtatcagc ggtgaatttt tcacctggcc
    35461 cctcaccatg acctggcaaa tcctcacgca gtggcagatc cccataaacc tcatcagtgg
    35521 acacatgatg gaagcgaata tcatatttac gagccgcctc taagagtgta taagtcccaa
    35581 cgaagttcgt gtaaataaat ggacttgggt cattgagtga attatcattg tggctttcag
    35641 cagcatagtg gacaatagca tctgccttag cggccagctt atctaccaat tcagcatcag
    35701 caatgtcacc aacaaccaac tccacgcgat cacccaaaat ctcctcaagg ttggcacgat
    35761 tgccagcgta ggtgagctta tccaaaacag ttacgtgaac ctctgggtga tggttgtaaa
    35821 cataatgtac gaagtttgaa ccgataaagc cagcgccacc ggtaacaata atgtttttat
    35881 attcagacat gttttttctt ttcctttgtt ttcagctatc agcactcaaa atgcagctta
    35941 atccgacagg caagctcagt taccagtgaa aacagcgact aagctgcctc acctcattgc
    36001 tcctaccatc cataaggtcc ttcctatcag aaggatacag agacactccc atcaaaagcc
    36061 atagcttatt tcaaatgcta attatgataa atcttcttgt ctcaaaggct taacggcctc
    36121 taggaaggga tggcttttat ctgcttctga aacctctgct tgttcaagac tttcccacgc
    36181 aatcccaagg cttgggtcag cataattaac aaaggcatat ttttgcttga gctcaagcgc
    36241 ccaataatca ttgaccagat aggtataagc caccttatca gtcagtactt gaaagccatt
    36301 agcaacacct cgagggacaa aaatcccctt tgaagcgtca atgactgttt gataggtatg
    36361 cccaaagcta tcaccctcac gaagatcaac ccaagctcca agaaccttac cctcatcagc
    36421 aacagagatg tacttgtccc aaggctctgc atgcaggcct cgaagcacat gcttgcgcga
    36481 aaatgaaata ttgttttgca gcttacctgc ggcaaaaaac tgctcaggaa agcctagagg
    36541 aatcattttt tccttttgaa aattttcctt aaaccagcca cgattgtccc ctcgaacagg
    36601 gatatcaaac tccaaaagtc caggaatggc ttcaatttcc cgacaggcta aggctttatc
    36661 aaaaaattgt tctgtcatca agcttctcca atcaaccgca gcaggtactg cccgtattcg
    36721 tttttcttaa gcgactgcgc tagctggtag acatcttctt tagtgatata acccatgcga
    36781 taggcaatct cctctaggtt ggccacctga gcgttttgca agcgttgaac tgtctcgatg
    36841 tattgggcag cctccagcag gctttcatga gtgccagtat ctagccaggc aaagccacgt
    36901 cccatcaact caaccgatag gtcgccacgc tctaaatagg ctttattaac atcagtaatc
    36961 tcaagctctc ctctggcact tggtttaatg cttttagcaa tctcgactac atcattgtcg
    37021 taaaaataaa ggcctgttac agcaaaatgt gacttaggaa ctgccggctt ttcttcgata
    37081 gaaatggcat tcatctcatc gtcaaactcc acaaccccaa aacgctccgg atccttgacc
    37141 tgataaccaa aaacagtggc tcctttttcc ttagctgctg ccttttggag cattttcgta
    37201 aggccgtttc catgatagat gttgtcacct aaaatcaagg caactcgatc atcaccaata
    37261 aactcctcac caatgataaa ggcctgtgct aagccgtcag gacttggttg ctccttgtag
    37321 gacaagctta tcccaaactc tgagccatcg cctaatagct cttcaaatct tggaagatct
    37381 tggggagttg aaataatcaa aatgtctcga atccctgcca gcatcagtgt tgataaggga
    37441 taataaatca ttggcttatc ataaattggc atcaattgct ttgaagctgc acgagtaaga
    37501 gggtacaagc gtgttcctga tcctcctgcc agaataatac ctttcatcgt agctctcctc
    37561 attttataat acgtcactat tttatcattt tttaaaaaca gtgtcacttt ttatcattaa
    37621 tccgacgaat ataatgatga atcgggtatt gactagtatc taagctagct ttttgcccca
    37681 aaagcagggc aatcagctgc tgagcaatca aaggacctag ggtcaagcca gatgagccta
    37741 gaccgcttgc ggcgtaaaca cctggtagct gaggtacctg cccaaaaaat ggagaaaaat
    37801 ctctggtata ggctcgaatg cctacgcggt aagaaacatc agaggcagaa ctcagcttag
    37861 ggtaataggt caaggcctcc tgctccaagg cctctaaaac agctacatca ggctcaaggt
    37921 catagccctt atcattttca tgactcgctc ctacagacaa cctatcatgc tcaaagggaa
    37981 taatatccag ctccccctct ggcatgacca ctgcgtagtt atctgtagtc acattcgcaa
    38041 tgtgataatc aatgagctgt cctttttgcg gtcgaatatc cacctgatag ccaagtggct
    38101 caagcaattc tggcagccaa gcaccagcgg ctagaatcag ccgatcaaag accataccat
    38161 caacgagata gccttgcttt tctatgctta tgccaacacg ctttttaacc acctgatagc
    38221 cactagcttc aagcaaacac tgacataggt ctgccccatc aacacgtgca gccccagaag
    38281 cccataccag ctgctcaaaa ccctgtaaat caggaaaatc aaccctaatg tccgaacgac
    38341 accttatcgc caaatctcca atcaaaggcg actcttgctt gcgtctaatg gccagctggt
    38401 agagctcctc tagcttgtcc tcattctttt ttaataaata aacaccagtc tgcttataaa
    38461 aatgtgtaga aagcccctct ttttgcagct ccttgattaa gtcctgataa caatctgctc
    38521 ctaaccgagc cagctggtac caagccttat tccttctttt tgaaaaccaa gggcagataa
    38581 tgccagcggc tgccttagtt gcttgaccat taccatcatc aaaaatagta acctgctgat
    38641 acccttgttt ttttaaataa taagcggcgc ttgaacctac aattccagct ccaatgattg
    38701 ctatcgttgt cattgccgtt tccattctat catactgctt accaagcata ggccatactc
    38761 agtcatgcta tagatgacta aagggatttg ttgacgcctt gctagccata atggttactt
    38821 gccagccttc ctcttttttc caagcctgca tcttggcaag tagtttatca ataaataagg
    38881 actcgatgtg atgccctgga tcaattgcca gcaggccttc tgtcagcatt tcctgtgctg
    38941 tgtgataata aatgtcacca gtaatataaa cttgagctcc cttagcaagc gctgcctgat
    39001 aaaatttatc accactgccc ccacaaatag ccactcgcga aatcaaaggg ttttgaccag
    39061 tatatcgaac cagccgaacc acatcaagcc caaaggcttc tttaactgta agtcctaact
    39121 cctccaagct ttgctctgct acatttccga cacgtccaat accataccca tcttgcgtct
    39181 caaccaatac ctctgtctgc tcaatgccca acagctcaca aaaccaatcg ttgagcccgt
    39241 cagagacaat atctatattg gtatgactga catagacaga aatatcgtgc ttcaccagct
    39301 caaggacaat atctcgctgt ggcgaggaga ccaagtcctt caagccctta aaaataggag
    39361 cgtgcttggt gataatcagg tctaccttgg ccgcaatagc ttcggcaacg gtattttctc
    39421 tcacatcaag ggtgatcatt acccttttga cctccttatc cagagagcca atttggaggc
    39481 cacacacatc tcctgacatg gatagctcaa gcggacaata gctttcatat ttttcgatga
    39541 ttgttctagc tttcatgact gatgacctcc tcaatcgctt ttattttttg agaaatgcta
    39601 gcgcgttcaa caggcttcgt tgctggcaca caagacaggg catagacaag cttatctcgc
    39661 tctttttgcc atttagccac aaagactgat gacctttcct gagacaagaa aggaccaaag
    39721 cgctgctcct gatctgttag actttgttga ccaggctctg caacaatgat ttcataatat
    39781 ttgccatttt ctgtcatgat ggtttcagca ctaatacaaa aagcattggc agatagccaa
    39841 gcacgcagct catcctctcg attattgggc tgtaaaatca agcgctcaat cccttgcagc
    39901 ttttccttac cagccgctaa aatgtcagct attaaacgcc ctcccatgcc acagatggtt
    39961 atgcagtcta cagcatctct cgcctcaaag gcagctaagc cattagccag acgcacctca
    40021 atatgctctg tcaaaccata ttgtgacaca ttttttaggg ctgatacaaa aggtcccttg
    40081 accacctcac ctgcaatcgc ctcttgaata tgctcggttt caaccaaaaa aataggaaga
    40141 taagcatgat cacttcccac gtctaaaagc ttagcaccat cagggacata ggatgccaca
    40201 tggcgtaagc gctttgataa atgactttcc attttcttaa tccttctaac aactaatcgt
    40261 atcactatta tagcaaaata cagaccaatt aaaaagaaag ccacatcaga ccttcttttt
    40321 accataggta gtcttgtaat agctgcaata gctctgtact gggcaggtat cacacttagg
    40381 atgcttagcc aagcagtgat agcgtccaaa aaagatcaaa cggtggtggg tgatgatcca
    40441 atccttctta ggaagcttgg ccatcaaatc agcttcaatt tcagtaacat cggcatctgg
    40501 ggcagaaatg ttcaagcgct tggcaatcct tgacacatgc gtgtcaactg cgattgcagg
    40561 gacaccataa atctctgcca agaccacatt agcagtctta cggcctactc ctggtaagga
    40621 ttcgagctcc ttatgggttt ttggtacctg accatcaaac tgtgtcagta gctgctgagc
    40681 tgtcttgatg atattttttg ccttattttt atacaagcca attgtcctta ggtgatcctc
    40741 aacatctgac acatttgcct gagccaaatc tgaaagctct gggtagcttt gccacagctt
    40801 aggggtaacc ttgttgactg ccttatcagt tgtctgcgct gataggataa ccgtaataag
    40861 aagctgaaag ggcttttctt ggtcccaatt cagctcgccc ttagcctctg gaaacatctc
    40921 accaatgatt gatagaacct tttttaatcg ttctcttcct atcctcatta gttactccaa
    40981 aggttcatcg ccgcaagaaa atcatctgaa accgtcactt cagacgccgt catatcctct
    41041 ctggcacgct ttttttcctc aagctgcctg aggcttgtaa ttccctcctt gcgccaattt
    41101 cttagaatag cctgaatata tttccaattg gtttttccat taaagacagc ctctctcagc
    41161 gcctcacgca ctaaatccag atctgtttgg tcatcatgaa tggttttttc caaatcctct
    41221 agctccatcg gactcaaaaa acgacccagc tcacgctcaa actcatcaac aagaagtttc
    41281 aattggttgg tgttttgctg ttcatgctca cccttttcat cacgcgccaa tagctggtct
    41341 aaagtgacta atacaggact agcatcaaaa atgatctcaa tctctccagc cagctctatg
    41401 gttttcatat ctaataaccc ctgactggtc aaggaagaaa tagccttatt cacctctgct
    41461 acagacttac ccaaggcatt agcaatctga ctaggtgcca attcgtcaag cctagtcgta
    41521 ttttggagat agaaaaactg ccaaaccaaa aaatcgtctg agctcttaaa aatatccttg
    41581 taatgaaaca gtaaggcagt tggaaggacc aaattgccag actgataatg ctctaaaaaa
    41641 ctcataattc ccctgccaaa cgtaatagcc caacctagct tttaatcagt actgccatta
    41701 gcaagcactg attaaccagg aaaatgcatc aataccttac aatcgtaatc accaatagcc
    41761 tgacgaccat tcaagccgtc cagctcaatg agaaaagcgc agccagcaac aatgccgccc
    41821 agcttttcaa ccagatcaat agtagccttt actgtaccac ctgttgctaa taagtcgtcc
    41881 acaataagga cacgttggcc cggcttaata gcatcagcat gcatggtcaa ggtgtctaga
    41941 ccatactcct tttcatagct agcagaaatc acctctcttg gcaatttacc cggcttacga
    42001 acaggagcaa agccaattcc tagctcaact gcgaccggac agccaataat aaagccacga
    42061 gcctccggtc caacaatcat gtcaatgtcc ttatcgcagg catattgcac aatctcacga
    42121 atagcatagc tgtaggcctt gccactagcc attagcggcg aaatatcacg aaaggtaatc
    42181 ccctcctttg ggtaattctc aattgaagca atatattgtg ttaaatccat cgtaaaatag
    42241 tctttctaat gtcttttaaa ttaaaatctt tcctattata gcatgaaagt ctaaaaaggt
    42301 aaatgattcc taatcatcca gatcaatccc tttttccttt aaattagtca ggcattcctg
    42361 taaataggcc tcttgatgct caggataaat cggtgaggtc agtgccacct cctctaagtc
    42421 ctcataggcg gcaaggcttt ttcctcggta atttttatcc tgccagctca catctggctg
    42481 gtagccccgc gcctgcattt cctgcataat caacaggtga tactggtaaa gcttataaag
    42541 agaatgggca aacacatagt caaccgtcgc atgtggtctc ccccagcctg ctcctcgcaa
    42601 ggccgcacat tcacgatgct gccccaacaa ttgctgcctt ggtaggcgtg tgattaaatc
    42661 ctgatgccaa agacgcataa gctctcctat ttctcttcac tagtcattaa atactgataa
    42721 atctcctgcg gactgcccaa ggccataagc tcttgaaact ttaccagctc ttttagctgt
    42781 tggtaaatga cactgtcagc gatgctacgt tttggggcat cagtctttac cctcatcagc
    42841 ccatcttcga ttactacaaa gcctaactcc tcaaaaattt gtatcatttt gaccaagagg
    42901 attttttcaa tcttgaggta atcacttagc aaggtcagct tatggcgaag atcaaattct
    42961 gggtattgat agatggtctt ataaagcttg gcaaattgct ctctactgcc atagcctgtt
    43021 aggtaataag ggcgcttaat atgattttta aagtaaatcg cttcaaattc ccgatgtcta
    43081 aaaaggcctt tcaaggcatc aatatcgtca ggaacctcat ctatgacaac aaccttggcc
    43141 tgctggtcct caacagctgt aggaatatgc tcaggtgccc tagcagtcct tgctcgaata
    43201 tcaaacagct gcaccccagt cactctagcg tcaaccagca ttaattgcag gctagtatga
    43261 cctcgccagt gattgatcgc aagactaacc gctaattcca agccctgtga ttgctggtac
    43321 tcctgtatca gatgtccctg accaaaggcc aagacatcag cctcaacggc tcctttgctg
    43381 accttgaact tcaagtgact ttgttgctga ccaatggtcc ttgcctgctt aatcgtaaaa
    43441 tcttttaagt aaaaaacagg ctttttatta tccatgccaa agggtgctag aagtagcagc
    43501 ttgttcagac tatctatact caatgcttct aaatccaatt caccattgat caatagagtg
    43561 tttttttcct gaccatcgtg tcccttggct gccacgtatt ggcaaagtag ctctgatagc
    43621 tcctctaggc gatcagatgg cagagtcatg cctgctgccc cctcatgacc accaaaggct
    43681 gtaaataagc tcctattgct attaagtgct tcaaagatat taatgctctc taagcttctg
    43741 gctgagccct tggctagccc ctcatcaatg gtcaaaacaa gaacagtctg cccaatctcc
    43801 tccatgatcc gaccagctac aatccctaag acccctgggt gccagccaga cttagctaaa
    43861 acctgcacag gcttgtctag atcaagcata gccattgctt gagcaaaaat ctcctgtacc
    43921 aagacctttc tttcctcatt tttactacta atcatcaagg caagctcatg aagctcttcg
    43981 tcatcaaagc ctgtcagtag atcaatagct ggatttggat cgtcaagacg ccctagagca
    44041 ttgagctgcg gagcaagctt aaagctaata acatcttcat caaaatgcgc taagtcaacc
    44101 tctgaaagct tcatcagctc ctgcaagcct agtctttctg tctcttttag aacagccagc
    44161 ccgtttttga caaggatacg gttttcacct cgtaggctga ccatatcagc aattgtccca
    44221 atagcaacca gatctaaaaa gtctactgga attgtctcta acagagctga agccaacttg
    44281 aaggcgacgc cacagccagc tagtttttga aagggataag cagcagctgg gtgctcaggg
    44341 tgaataatag caaaggcatc aggtagctct gctggcaggc tgtggtggtc tgttacaata
    44401 acatctaccc cctgtgcttg cgcaaaggca accgcttcat ggcctgaaac accattgtca
    44461 acggtaataa tcagcgaaac ctgctcttgc tcgatgaaat acttgtaaac actttgattg
    44521 ggaccatagc catctgtaaa gcgattaggc aaataaacaa gaggctctgc tcccatcatt
    44581 tccagcgttt ccttgacaat agacgccgct gtcatgccat ctgcatcata atctccgtag
    44641 accaaaatcc tctcaagccc ctcaatggcc tgacgaatgc gatgaacagc tttttccata
    44701 tcatttagca aataagggtc atggagctgt gataggtcag ctgtcaaaaa gctggtaagc
    44761 tcctcttcgg tatgaacacc tcggtcatag atgagctttg cagctgtctg actaagtccc
    44821 tttgcctgag ctagcttaaa gaagccagca tctggctcct tatcagctat ggtccactga
    44881 tatttggacg taatcattta taattaaata cctttcttgc aagataatca gatatagttg
    44941 gaaacaaggt ataacactta tgagcaaggg ctaggctaat aggcagatta atctctcgtt
    45001 tcttttttcc tattgcagca atgatttttt tcgccacagt atccgcctgc agcgtaaagc
    45061 ctgcaacact ggctaaatac tgcccgcttg ggtcagcctg ctcaaaaaag gaggttgcaa
    45121 tcgggcctgg attaacagtt gtcacataaa cctgcctttc tgccagctcc aagcgaaggg
    45181 cattagaaaa gccaatgact gcaaactttg tcgcagaata gatacttgac ttggcagaag
    45241 ctattaagcc tgccattgag acaatattca taatatgtcc agagccctgc tctgccattt
    45301 tgtggccaag caagcgtgca aaatgaatgc tggctaagct attcacacga aacatggcct
    45361 caatctcttc tgcagagaaa tcatcaaagg ccttaaaagc accaaagcct gcattgttaa
    45421 tcaaaacatc aatcctgcca tggcgctggt aaagctcatc aacaagagcc tcaatagcag
    45481 cagggtcttg aatagcaatc tcgtagcatt ccttattacc gcgagcctga tatagactgt
    45541 ctaacctgtc tttgctgcgc cctaacaaaa tcaggtaatc ttctcttgga agctgtctga
    45601 tgatagcctg tgcgagcccg ccagaagcac ctgttatcag aataattctc tgtgccatta
    45661 aatgatcact tcctctaaat cgcgaacaac cttcacattt tcaaaaatag ttgccgcatc
    45721 cttttccatt tgacgacagt cacgtcctaa aaagcgtgct gaaacatgat tcagtaaaag
    45781 acgcttagca cctgcatcac gcgcgatttg agcagcctgc atgtttgtcg aatgcccatg
    45841 attacgggcc attctttcat cacccttccc gtaggtggac tcatgcacca gcacatcagc
    45901 atcttttgcc aatctaacac tagcagatgt cttgcgtgta tcgccaataa tggtgatgat
    45961 ctttcctttt cgaggctctg aaataaagtc cttggcaaaa attttggtgc catcctctag
    46021 ctcaatatcc tgcccatttt taaccttgcc aaaaagtgga ccaaagggca ctcctactgc
    46081 tctaagagct tctgcatcaa gtgttccttc taaatccttt tgaaccacac gataccccat
    46141 acaaaagatg gtatgtgcca agcgctcagc ataaacaata aatttatctg tttctaaaat
    46201 cttgcccata gaggtgtcat caaactcatg ataatgaatc tgataaggca atttagagcc
    46261 tgatatcctg atgctgtttg ttacatagga ttttatccca acaggtccat aaatctcaag
    46321 gtccgtctgc tcctcactag cttgaaaagc ccgactagat aaaaagccag gcaagccaaa
    46381 aatatgatca ccatgcagat gcgtgataaa aatcttcttg atttttcgtg gcttgattgt
    46441 tgtttctaaa atttgccgct gggttccctc gccacaatca aacatccaca cctcattgat
    46501 ttcatctaat agctttagca ctaagcttga aacgttgcga tgcttggctg gctgcccagc
    46561 tccagtacct aaaaattgta attccataca gtctattctt tctaatgcac aaggtaaatc
    46621 atgaattctc tttgtgcaaa ctgataatat ttctttcctt tgaatgcttg gctaagagcc
    46681 aacaattcat cactattaaa gccctttagc agggtcattt cgtttgagaa acgatagatc
    46741 gtggttaaca aagcatgctc aggtgttatg tcctctggct ctccttgctc aaattggcag
    46801 ctcttcatct tgattctacc atcttccaca taaaccacgt attgtggaaa aatctgagcc
    46861 agctccagca gcagcgattc ctcaggctgc ccctgctctt tttcagcaaa aacaatcgcc
    46921 tcctgtgctt cattttcaaa gacaaagcca taggattgcc ccaacaaatt taagcggaca
    46981 aagggcttca cctcatcaaa tgacggctct gaggtaaaca gcttcaaggc ccttgatagc
    47041 tcaaaataat aatctgtcgc tgcttttggt gattgcttct gatacatttc tgcaaaataa
    47101 gcattaatca cacttggggg tggcgtgatg gtagctaatt tttgctggtc tgtcaagccc
    47161 tttaagcaat tttgcaaata aaccgtatct aaactcgtaa agcctccata agtctttgcc
    47221 aattgaatat aatcagtcat aaaattcttc taatctccat ttatttttgg gagcaatgta
    47281 gccagaaatc tcttcaatct ccttatcaaa gctataaggc tccaataacg ccaacctgtt
    47341 gaggtcatag catttgtagg cttgatcctg acagagcttg atcgaaaatg gctcaaacat
    47401 gtcccgaatc tgatcaataa gcaactgtct taagaggcta cgactgtttt tatcacgtgc
    47461 tgacagcctg acatttggaa aaacagttgc agtcaagcta gctgtcttat ccatcttgtt
    47521 ataaatagcc agccttggaa tatccagcat atctaaatct ttcaagatgt ctagaacaac
    47581 cctctcatgc tccaaatgat tagggtcact ggcatcaatc acatgcaaga gcaaatcaac
    47641 atgccgactt tcctctaatg tcgacttaaa agcagccacg agctccgttg gtaaatcttg
    47701 gataaagcct acagtatctg tcagagttgc ctgaaactga ttttgcagat aaatttgctt
    47761 ggtggtggca tcaagtgttg caaataattc atcagcctca tattgcttgt caccagtcaa
    47821 aatagtcata atagtagact tacctgcatt ggtatagccg atcaatccaa tattaaagac
    47881 atcagaggtc atgcggcgat cacgaatcgt ttgacggttt ttttcgacag cagctagctg
    47941 ccgctcaata tctgcaatct gatgacgaat ggagcgccgg ttcagctcca gctggctctc
    48001 acccggccca cgactcccaa tgcccccggc ctgacgacta agcataacac cctgtccgac
    48061 cagtcttggc agcatgtatt tgagctgcgc taaatgcacc tgcaatttcc cttcatggct
    48121 tctagcccgc atcgcaaaaa tatcaagaat cagctgcatg cgatcaatga ccttaatacc
    48181 taaggcgtcc tccaaattgg cattttgccg agccgttaaa cgattgttaa caatcactgt
    48241 atcaatctca ttggcagcaa ccatttcttt gatttcagcc agcttaccag agccaacaaa
    48301 ggtcttgcta tcatagcgct ccctcttttg cagatagcaa tcaacgacct ctgcacctgc
    48361 ggtcttggct agactagcca gctctgtcat tgatagctca gcatggtcag ctgcttgtag
    48421 gaccacgctt agtaaaataa ctctttcctg ccttgccttt gtctctatca tgaacgcgac
    48481 taatcctcca aattccgtag tgtttattat agcatagttt tagctatttt cagctagttt
    48541 gccatcgata gcttcctaag gctccttcaa aaagcgctcc accctatcat atattgcctg
    48601 cggataggac gactcgctaa tcgagtcaaa gcgcactgcc atacggttac gaaaccaagt
    48661 cagctgtcgt ttagcaaagc ggcgtgtttg ctgctttagt gtggctgttg cttcttctaa
    48721 actagcctga ccctgaaagt aagggaagag ctccttataa ccgatccctc gactagcctg
    48781 aacagctgga tactgctcaa aaagccacct tgcctcctcc aataggccag aagccatcat
    48841 cagatccacc cgcttattaa tccgctcata aataacctct cgctcatcag tcaagccaat
    48901 gatcaagggg ttataggggg cctcttgatt ttctaaatcc ctagcaaatt gatttagctc
    48961 aagtgagcga atggcacgcc tgcggttaac ctgatcaagg tgaatgccct tactagctaa
    49021 tagctgataa agctctgtat ctgtcagtgt ctctagctgc tgccgataag caagtagctc
    49081 cttttgatca agatctcctc ctagatgata gccctctaac aggctttgca aatacaggcc
    49141 ggtaccaccg acaataatcg gcagtttacc gcggctaaca atatcttcaa tagctcgctt
    49201 agcgtcctgc acaaaatcaa aggctgagta agactctgtc acctcacgaa tgtcaatcaa
    49261 atgatgaacc gcaagagcct gctccctggc actagcctta gctgtcccaa tatcaaggtg
    49321 acgataaacc tgctgactat ctccagatat aatttcacca ttaaaggcac cagccaaggc
    49381 aatccctaga gctgtcttgc caacagcagt cgggcctaca atcacaatta tcttttcttt
    49441 tgtcatttat tgtctttcta cttaaaaagc agctgaaaaa gtcttttact tgaattttct
    49501 aatctttttc gctaccatat attataacat aagattgaga gacagttatg gtcctcttaa
    49561 tagaaatgga gaatgattat ggctaaaaaa catggattcg caaagggtct tgctacaggt
    49621 gttcttgcta ctgctgctac cgttgcaggt gcagtatttg ctgttaaaaa gactattatt
    49681 gaccctgagg aagaaaaagc agcatttgta gaggaaaatc gtaaaaaagc agcacgtcgt
    49741 cgtgttgctc gctaatcact aatagatgaa agattcgaca ggctttatca atagcctgtc
    49801 gaatttttta tgctgtgaga ccaagctttt tgcttagaca cataaaagaa acagctcgtc
    49861 agcgccgcat actgcctact tcattgacca acaaacaggg caaactaagg ctaattttca
    49921 ctgatatgac atgtttcgac tataaagcgg ttttgtgatt gattgatcac aatatcaaat
    49981 tgctggtgat aagggtgcag ataacgagca tattgagcgc gcctattgac atgatgaact
    50041 ccggattgcg acctctaacg ctagtatctc taccaagccg cctttggagc tctgtgtcac
    50101 catctgtata aaagtaaagc gataagtcaa acaactctgg ctctaaaaag gttgtcgaca
    50161 tgccttcagc aataaggatg ggcacattcc ccttcaccaa aaaagaggga gaccaagggg
    50221 tatcaatact caaaaaatcc agtccttgct taaacatcat gatgtcacgc ctcagactgg
    50281 ccaattcgtg cctagcaggg tgacaggctg ttatactacc aagtacctcc tctccctgat
    50341 cagggtagct aatcaaaaca gcctgactaa aatcattagc gatgatatag gcatctgttt
    50401 ctaacaattg gctttgtcca tcaggcaaaa gctgctgtaa gcgcttagca aaggttgatt
    50461 taccagatgc accatgacca ctaattctaa taagcatttt ctcacgattg gctgctgcag
    50521 ttacaatagc ttgaagtagc ttctccatta tctctcctca tcaaataaca ttctaataat
    50581 aggacatcat tctacatcga aaaacaagcc ggtctcccga aacagcctga ctgacagtaa
    50641 aaaaagattg aagggcaatc caataaggaa agcttctcca atctgattaa tagtctataa
    50701 tggcttaata tgagtgccaa atgtcttggt tatattgttc aatcgtacgg tccgatgaaa
    50761 agaagccagc cttagcaata ttatgcacaa cctttgtcag ccataggtcc tgattgtcat
    50821 aatcagccag catttgttct ttgactgcaa tgtattcctc aaggtcaatc aaggtcataa
    50881 accagtcctt agagattaac tccttataga gacggtcaag acgttcctca ttaccaagct
    50941 ctaataattc tggactgata ataaagttaa ctgcttcctt gatagctggg tgggcatcat
    51001 aatagtcttt agacacataa ccacctgtgg cataaagatc aataatggta tctgaatcct
    51061 taccaaaggt gtagatatta tccataccag caagctcagc gatttccaca ttagccccgt
    51121 ccatagtacc aagcgtcaag gcaccattga gcatgaattt catattacca gtacctgaag
    51181 cttcctttga agctagagaa atttgctctg aaatatcagt tgcaggaatc aaatgctctg
    51241 ctactgtcac attgtaattt tcaacaaggt gaacattaag gtatggactt acctccggat
    51301 cgttattgat aagctctgac aagcaaagaa tcaaatgaat aatatcctgt gcaatgatat
    51361 aagccggtgc agccttacca ccaaagataa ctgttatttt acgcttcggc aggttgcctt
    51421 ttttgatctc taagtattta tgaatcacat aaagggcatt catctgctgg cgcttatatt
    51481 cgtggaagcg tttaatttgg gtatcaatga ttgaatgctc atcaagctca attcccttat
    51541 tatccttgag gtagcgcttt aaggctactt tattatggtg cttaatttca gccaatcttg
    51601 catgaacagc ttgatcctca gcaaaggcca ttaatttttc aagccttgtc gcatcagtca
    51661 agtaagcatc accgataagc tctttaatat agtccgccaa ctcttggttg gcgaattcta
    51721 gccaacgacg gaaggtaata ccattggttt tgttgttgaa tttttctgga tacagctcat
    51781 agaaggcctt caattcgcta tttttcagga tttcagtgtg aagggcagca acgccgttga
    51841 cacttgtggc aaaatgaata tccatatgtg ccatatgcac gcgacctgtt tcatcaatga
    51901 tttggacagc tggatctgat acccttgcac gaacaagagc atctaattgc tcgataatcg
    51961 ttaccagctg cggcacaacc tcattaagga agtcaagagg ccatttttcc aaggcttctg
    52021 caaggatcgt gtgattggtg taaccaacca tcttttgaac cactgaaaca gcctcatcaa
    52081 aatcaaagcc atgcttttgt gtcaatagac gaatcaattc tggaatgacc attgatggat
    52141 gggtatcatt gatctgcacg tatgcgtaat cagctaagtc atgcaggttt gagccacgct
    52201 caagcgcttc atcgatcaag agctgagcgg cattagatac catgaaatat tgctggtaaa
    52261 tgcgaaggag ctcaccattt ttatcagaat catcagggta aaggaacagg gtcaggtttt
    52321 tggcaatgtc agtcttatca aatgaaatgc catctttaat caagccataa tcaacccctt
    52381 caatatcaaa aaggttaaga tagttcttgg tgtcacgctt atagcccaaa acatcaatac
    52441 ggtctaagcg agatttcagg gtaaagtttt taaagggaac atcatatgaa atgtcagtcg
    52501 gtactagcca agagtcatcc tctatccaaa aattaggctc tgctgtttgt tcattgtgtc
    52561 taaagacctg cttgaacaag ccacaatgat aattcaagcc aaccccttca ccattaatgc
    52621 caaggcttga gatagaatca ataaagcaag aagccaaacg accaagacca ccattaccaa
    52681 gcgatggctc caattcaacg tcctctacct cagcaattga tttgcccgca gcagccagct
    52741 cctctttgat gtccttataa atacctagat taatgagatt attagaaagc aacttaccaa
    52801 tcaaaaattc tgctgagatg taataaacct tacgtttagc tgtgtttttt gcttttttgc
    52861 ttgcttcttc tttgagatag gaaagcaacg aaagatagat ttcctcgttg cttgcacttg
    52921 caagagattt tcctaatgtc atttcagtat aatctgtaaa gcgtttcatg atatcctctt
    52981 ttcaatatag tattctagtg atgattattg gctcgaccgt atagctcagt caaatggatt
    53041 aaataggcct tgtgctctgc tttaatatcg tcctcaagca tgcgccactg ccagttgcca
    53101 ccgacagtgt ttggcatatt catgcggcta tcagctgact tatccagcaa atcctgcata
    53161 cacaggatag cagtatcaca cacagtcgca aagattgttc ttagcatggc cttggtgatg
    53221 ctttcagcag ctgccttatg gatataatga ttaacaaact caacctgctc tgcgctcaag
    53281 tgctcatacc agccattcac cacctcattg tcatgcgtac cagtgtagac aatgcaattg
    53341 tgatcatagt tatgcggcaa atcaaagctt tgacttgtca catcaaacaa accaaactct
    53401 aaaatcttca tgcccggaaa gccagtagat gccagcagct gctcagcctt ttcatcaatg
    53461 tagccaaggt tttctgcgat aattggcagc tcacccaagg cctctcgaac agctttaaat
    53521 agagcaatac caggagctga ctcccaatga ccatttttag cagtcacatc accaccagga
    53581 atttcccaaa aatctgagaa gcccttgaaa tggtcaattc taagcttatc gtacagcttg
    53641 aagctctctt tgatccgatg gatccaccaa gcaaagcctg tttgctcatg gctctcccag
    53701 ttgtaaatag gattgcccca aagctgcccg tcctcactaa agccatcagc aggtacacct
    53761 gcaatgtaaa tcggcttttt atctgcatcc accttaaaga gctctggcat cgtccaaacc
    53821 tcaacgctat cagcagacac gtagattggc atatcaccaa tgatagtaat gccattttga
    53881 ttagcatagg tcttcagcgc tagccactgc tgataaaaga aatattggca gaccttatga
    53941 taggtgatgc ctttggccaa cagcttgcgg taatgaagca aggcagcctc ttcacgctta
    54001 acaattgctc tatcgtccca ttcctggagg gccttgtgat caaaatgctc tttaatagcc
    54061 ataaattcag caaaatcatt tagccagctc gcagttgctt caaattcggc gagctgtctt
    54121 aagccttcct cagttgagac aaaagcctga actgcttttt ctaataaagg gcgtctggct
    54181 tgaaagactt gagcgtaatc aacagactcc ggatttgagc caaaatcaac agcagcataa
    54241 tcagcttcct gcaaataacc gtcctttgcc agcaattcaa ggtcaataaa atgcgtattt
    54301 cctgcaatag ctgaaaaaga ttgataagga gaatctccaa agctagttgt tgttaagggc
    54361 aaaatctgcc aataggtctg cttggtttcc tttaaaaagt caacaaattc aaaggcctct
    54421 ttaccaaagc tcccaatacc gaagcgtccc ggaagcgagc tgatatgcat cagaatacca
    54481 cttgcacgtt tagtcattct ttttttctcc ttgtaaaatc ttaatgttga aattataacg
    54541 caaccgtttg cgcaagtcaa tatcttttca aaaaaaaaga gactttttcg gcatgctaga
    54601 gctgctcaag ccttgataat aatgagggaa gcagctagga caaaaacaaa aaaaggattg
    54661 gagagacagc ctaagcagct gctcttccat cctcatctca ctcctatttg gcattaatat
    54721 ccctgacact ctctcgcttt ttgaggctaa agggaaccaa aattttctga ctcagggttt
    54781 gttcattggc attgataatg tctaagagct gcctaaagga ggttcttccc aaattttcaa
    54841 cgttaatatc aaatgttgtt aagtaagggt gaatcaattt cgaatagcta gaattattaa
    54901 aggtaataat cgaaatatca tctggcacct taatgtcata aaaggacaag agctggacca
    54961 ttcgcaccga caaaacatca ccaatcacga ttaaggctgt ggccttaaag ctacgtatcg
    55021 tttcaataac cttttcgatg cttattggat cctttcgatc aaataacagc atcggtttgt
    55081 tttccaagga taatttcaag cagcccttga gatagccaat atagcgctca gaagctacct
    55141 ctgcctccat atcgtctgtg ataaacagga tctgtcggtg acccttttga tagagatgat
    55201 caactgcggt tttagccatt agctggttgt cattgtcaat ataggtgatt ttgttctcat
    55261 caccttctgg tgcgccaaca atgacaaaag gaatctggtt ggtcatcaaa tagcctctaa
    55321 caggatcttc ttgctcagaa tataatataa taaagccatc aacacgcttt tgcaggtgca
    55381 ttaacttaac ctggctcaat aaatcctcaa cagacatacc tgttgcaatg gaaacagtga
    55441 aatgatgttt cttagcttca ttggtaatgg tcgatagaat ttccataaaa aagggatcac
    55501 tcaaacgatc attagtgata atcggcggaa aaaccaggcc aatattatgt gtcaggccac
    55561 tagcaagcat ttgcgcagct acattcggaa catagccaag ctcgctcata gctcttctaa
    55621 ccttttcctt tgtcttttgg gagatagatc gattatcctt gaggacacga ctgacggtcg
    55681 aaggattaac acctgctttt aaggcaacgt cttttattgt aaccatataa acctcattta
    55741 atacctgata atgacgctat gtcaggcttt ttcacatgta ttttgctttt attatacaat
    55801 tatctcctaa aaaatcaact ctcgccctgc aagaaggcga cataaaaaac tgctgtcctc
    55861 atgatcgaaa aaatgttaaa aaaatcaact ttttttaaaa aaagactaga ctttttctgt
    55921 aaacggttgc ataatattaa gtgtaagaaa tatatcttag gaggaaatcg ctatgaaatc
    55981 atggcaaaaa gttatcgtca gtggggcaag cttgacactt gctagcgcct tattagtagg
    56041 gtgtgcatct ggttcaaagg acaaaacaga aactgcatca ggtactgatt caaaaacaat
    56101 taagctttgg gtaccaacag gagctaaaaa gtcatacaca gatgttgtcg ctaaatttga
    56161 aaaggactct ggctacaagg ttaaggtgat cgagtcagag gatccaaaag cacaagaaaa
    56221 aatcaaaaaa gatgcttcta ctgctgccga tgtcttttca cttcctcatg accagcttgg
    56281 tcagctcgta gaatctggca ttatccaaga agtcccagag gaatacacta aagagatcgc
    56341 tgatacagca actgatcaag ctatccttgg tgctcaatac aagggtaaaa cctatgcctt
    56401 cccatttggt attgagtcac aggttctctt ctacaacaaa actaagctag ctgctgatga
    56461 tgttgcttca tacgatacca tcacgtctaa ggctaccttc ggtggtacct tcaagcaggc
    56521 taatgcttat gctactggtc cattgttcat gtctgttggt aacacattat ttggtgaaag
    56581 cggtgaagac actaaaggaa ctaactgggg caatgaaaaa ggggttgctg ttcttaaatg
    56641 gatttcagac caagcctcaa acaaaggatt tgttaactta gatgccaaca acgtcatgtc
    56701 tcagtttgga gacggttcag ttgcttcatt tgaatcaggt ccttgggatt acgaggcagc
    56761 acaaaaggct atcggtaaag aaaaccttgg tgttgctgtt tatccaaagg taactatcgg
    56821 tggcgaaacc gttcaacaaa aggccttctt gggagtgaag ctctatgcgg ttaaccaagc
    56881 tcctgctaag ggagatacca agcgtatcgc agccagctac aagcttgctt catacctaac
    56941 aaatgctgaa agccaagaaa accaattcaa gacacgtaac atcgtaccag ctaacaagac
    57001 cgttcaagct tcagaggctg ttcaatcaaa cgagcttgca aaaacagtta tcacaatggg
    57061 atcttcttca gattatactg ttgttatgcc taagcttagt caaatgggta ccttctggac
    57121 tgaaagtgct gcaatcctta gcgatgcctt caatggtaaa atcaaagaag gtgactacct
    57181 tgctaagcta cagcagtttg acaaggacat tgcagcaaca aaataagcta tctcatttat
    57241 aatactatcc taaacaagta cagaggtggg ctattttaac gctatccttt ctactcatct
    57301 ctaaaggggt ggaactaagc atcattattt tttcagggct tagtccactc ctacttgttt
    57361 ttgatatgac gtaaagcttg gtgctactta aatttttaat cgcttaaaga tttaggtaac
    57421 acttagctat gtggtcgtta gcaccaaacg cttatgacca cagcatctga acaagagagt
    57481 caggtaatcc tactttcttg tatcctaaca taaaggagaa catatatgac tcaggcaggc
    57541 ttagcatctc aggttactgt aaaagaggct ttaacaaagg gaagcttcga tattaaacta
    57601 tccgctatca tcatgggctt tgccaatttt gctaataaac aattcgtcaa aggaacactc
    57661 tttttattga gtgaggtggt ctttttcatc gcctttgttt cacaaatcat tcctgctatt
    57721 ggcggcctca ttaccctagg aacacaaaca cagggcatga caaccaaaac tatcgacggt
    57781 atcagcattc aggttgctgt tgatggagac aattcgatgc taatgctgat ttttggctta
    57841 gcctctctga ttttttgttt gttatttgcc tatatttatt ggtgtaacct aaaaagcgcc
    57901 cgtcacctct acatgctaaa gcaagaaggg gcaaaaatcc caagctttaa ggaggatttt
    57961 gttagtctag caaatggtcg tttccatatg accttgatga caattccatt gattggtgtg
    58021 cttctgttta cggtacttcc tttgatctac atgatttgct tagcatttac taactttgat
    58081 cacaatcacc tcccgccaaa gtcacttttt gattgggttg gtctttccaa ttttggtaac
    58141 gtgttaagtg gtcgtatggc aggaaccttc tttcctgttt tctcatggac actgatttgg
    58201 gctgtctttg ccacagtgac taacttcttc tttggtatca ttttagcact cttgattaat
    58261 accaaaggct taaaattgaa aaaaatgtgg cggaccttct ttgtgattac catcgcagtt
    58321 cctcagttta tttcactgct gattatgcga aatctgctaa atgaccaagg tcccttaaat
    58381 gccctgctta gcaaattagg gttaatccac cattctctac cgtttttatc tgatccaatt
    58441 tgggctaaat tctctattat ttttgttaat atgtggatcg gtattccatt taccatgtta
    58501 atcgcaacag gtatcattat gaacctgcca agcgaacaaa ttgaggctgc agagattgat
    58561 ggggcaagta aattccaggt cttcaaatca atcaccttcc ctcaaatcct cattatcatg
    58621 acaccaaacc tgattcagca atttattgga aacatcaata acttcaatgt gatctatctc
    58681 ttaactggtg gtgggccaac caattcagcc tattaccaag ctggaaccac cgatctattg
    58741 gtgacttggc tctataaatt gactgttaca gcagcagatt ataatctagc ctctgttatt
    58801 ggtatcttaa tctttaccgt atcagcaatc tttagcttac tggcttacac aagaactgca
    58861 tcatacaagg aaggagcagc gaaataatga aaaacaaacg tcgatttcag cttggattag
    58921 tttacgccat tttaaccgtt ctctcaatca tttggctttt acctatcgct tgggttgttc
    58981 tgactagctt tcgtgctgaa ggcactgctt atgtcgatta ttttcttccc aagcacctca
    59041 cattagacca ttatattaag ctctttacaa atgaaacatt tccttttggg agatggtttg
    59101 tcaatacctt tgttgttgct atctttacct gtatcatctc aacctttatt acagtggcga
    59161 tggcttactc gcttagtcgg atcaaattca agtttcgcaa tcgtttctta aagcttgcac
    59221 tagtgctaaa catgtttcca ggctttatga gcatgattgc tatctactat atcctaaaag
    59281 cacttggcct tacgcaaagt cttaccgccc tagtccttgt ttattctgcc ggtgctgcac
    59341 ttggatttta cattgctaag ggcttctttg ataccattcc ttattcgctt gacgaatctg
    59401 ccatgattga tggggctact cgtatggata ttttctttaa gattacccta ccgctatcaa
    59461 agccaatcat tgtttacact gcactccttg cctttatggg accttgggtt gactttatct
    59521 ttgcccaagt gattttagga gatgcaacca gcagatatac ggtagctatc ggactctttt
    59581 caatgctgca gcctgacacc atcaatgact ggttcatggc ctttaccgct ggatctgtgt
    59641 taattgctat tccaatcaca ttgctcttta tgtttatgca aaaatactat gtagagggcg
    59701 ttacaggtgg ttctgtcaaa tagcagtaat gatcacgata acccttactc aaaaaatcct
    59761 tccc
//
LOCUS       DARYVE010000003        58070 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYVE010000003 DARYVE010000000
VERSION     DARYVE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58070
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..279)
                     /locus_tag="TVW25_000137"
     CDS             complement(<1..279)
                     /locus_tag="TVW25_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1377817.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILN"
     gene            684..1328
                     /locus_tag="TVW25_000138"
     CDS             684..1328
                     /locus_tag="TVW25_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377818.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1333..2082
                     /locus_tag="TVW25_000139"
     CDS             1333..2082
                     /locus_tag="TVW25_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1377819.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2187..2336)
                     /gene="rpmG"
                     /locus_tag="TVW25_000140"
     CDS             complement(2187..2336)
                     /gene="rpmG"
                     /locus_tag="TVW25_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1377820.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2352..2534)
                     /gene="rpmF"
                     /locus_tag="TVW25_000141"
     CDS             complement(2352..2534)
                     /gene="rpmF"
                     /locus_tag="TVW25_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1377821.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            2804..3634
                     /locus_tag="TVW25_000142"
     CDS             2804..3634
                     /locus_tag="TVW25_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377822.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            3694..4974
                     /locus_tag="TVW25_000143"
     CDS             3694..4974
                     /locus_tag="TVW25_000143"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1377823.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5179..6471)
                     /locus_tag="TVW25_000144"
     CDS             complement(5179..6471)
                     /locus_tag="TVW25_000144"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1377824.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6461..7177)
                     /locus_tag="TVW25_000145"
     CDS             complement(6461..7177)
                     /locus_tag="TVW25_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1377825.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7431..7655
                     /locus_tag="TVW25_000146"
     CDS             7431..7655
                     /locus_tag="TVW25_000146"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377826.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7666..8586
                     /locus_tag="TVW25_000147"
     CDS             7666..8586
                     /locus_tag="TVW25_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1377827.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8573..9313
                     /locus_tag="TVW25_000148"
     CDS             8573..9313
                     /locus_tag="TVW25_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1377828.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9470..11218
                     /gene="aspS"
                     /locus_tag="TVW25_000149"
     CDS             9470..11218
                     /gene="aspS"
                     /locus_tag="TVW25_000149"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1377829.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11211..12158
                     /locus_tag="TVW25_000150"
     CDS             11211..12158
                     /locus_tag="TVW25_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1377830.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12174..13055
                     /locus_tag="TVW25_000151"
     CDS             12174..13055
                     /locus_tag="TVW25_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1377831.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13199..14113
                     /locus_tag="TVW25_000152"
     CDS             13199..14113
                     /locus_tag="TVW25_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1377832.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14285..15679
                     /locus_tag="TVW25_000153"
     CDS             14285..15679
                     /locus_tag="TVW25_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1377833.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(15727..17418)
                     /locus_tag="TVW25_000154"
     CDS             complement(15727..17418)
                     /locus_tag="TVW25_000154"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1377834.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            17695..18132
                     /gene="argR"
                     /locus_tag="TVW25_000155"
     CDS             17695..18132
                     /gene="argR"
                     /locus_tag="TVW25_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1377835.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18134..18484
                     /locus_tag="TVW25_000156"
     CDS             18134..18484
                     /locus_tag="TVW25_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1377836.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18471..21026
                     /gene="mutS"
                     /locus_tag="TVW25_000157"
     CDS             18471..21026
                     /gene="mutS"
                     /locus_tag="TVW25_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1377837.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAVDDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21173..23155
                     /gene="mutL"
                     /locus_tag="TVW25_000158"
     CDS             21173..23155
                     /gene="mutL"
                     /locus_tag="TVW25_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1377838.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23166..24389
                     /locus_tag="TVW25_000159"
     CDS             23166..24389
                     /locus_tag="TVW25_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1377839.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24391..24987
                     /gene="ruvA"
                     /locus_tag="TVW25_000160"
     CDS             24391..24987
                     /gene="ruvA"
                     /locus_tag="TVW25_000160"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1377840.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            24997..25548
                     /locus_tag="TVW25_000161"
     CDS             24997..25548
                     /locus_tag="TVW25_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1377841.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(25984..26829)
                     /locus_tag="TVW25_000162"
     CDS             complement(25984..26829)
                     /locus_tag="TVW25_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1377842.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            27126..27698
                     /locus_tag="TVW25_000163"
     CDS             27126..27698
                     /locus_tag="TVW25_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1377843.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            27692..27982
                     /locus_tag="TVW25_000164"
     CDS             27692..27982
                     /locus_tag="TVW25_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377844.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            28668..29939
                     /locus_tag="TVW25_000165"
     CDS             28668..29939
                     /locus_tag="TVW25_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1377845.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            30033..31169
                     /gene="recA"
                     /locus_tag="TVW25_000166"
     CDS             30033..31169
                     /gene="recA"
                     /locus_tag="TVW25_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1377846.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            31545..31943
                     /gene="spx"
                     /locus_tag="TVW25_000167"
     CDS             31545..31943
                     /gene="spx"
                     /locus_tag="TVW25_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1377847.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            32056..32325
                     /locus_tag="TVW25_000168"
     CDS             32056..32325
                     /locus_tag="TVW25_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1377848.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            32322..32741
                     /gene="ruvX"
                     /locus_tag="TVW25_000169"
     CDS             32322..32741
                     /gene="ruvX"
                     /locus_tag="TVW25_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1377849.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            32751..33050
                     /locus_tag="TVW25_000170"
     CDS             32751..33050
                     /locus_tag="TVW25_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1377850.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            33598..35157
                     /locus_tag="TVW25_000171"
     CDS             33598..35157
                     /locus_tag="TVW25_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1377851.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            35254..37452
                     /gene="nrdD"
                     /locus_tag="TVW25_000172"
     CDS             35254..37452
                     /gene="nrdD"
                     /locus_tag="TVW25_000172"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1377852.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            37558..37704
                     /locus_tag="TVW25_000173"
     CDS             37558..37704
                     /locus_tag="TVW25_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377853.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            37732..38667
                     /locus_tag="TVW25_000174"
     CDS             37732..38667
                     /locus_tag="TVW25_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1377854.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            38680..39174
                     /locus_tag="TVW25_000175"
     CDS             38680..39174
                     /locus_tag="TVW25_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1377855.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            39184..39798
                     /gene="nrdG"
                     /locus_tag="TVW25_000176"
     CDS             39184..39798
                     /gene="nrdG"
                     /locus_tag="TVW25_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1377856.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(40256..40987)
                     /gene="yaaA"
                     /locus_tag="TVW25_000177"
     CDS             complement(40256..40987)
                     /gene="yaaA"
                     /locus_tag="TVW25_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1377857.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            41423..41626
                     /locus_tag="TVW25_000178"
     CDS             41423..41626
                     /locus_tag="TVW25_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1377858.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            41628..42081
                     /locus_tag="TVW25_000179"
                     /pseudo
     CDS             41628..42081
                     /locus_tag="TVW25_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            42091..42765
                     /locus_tag="TVW25_000180"
     CDS             42091..42765
                     /locus_tag="TVW25_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1377859.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            42795..43232
                     /locus_tag="TVW25_000181"
     CDS             42795..43232
                     /locus_tag="TVW25_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377860.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(43455..44228)
                     /locus_tag="TVW25_000182"
     CDS             complement(43455..44228)
                     /locus_tag="TVW25_000182"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1377861.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(44312..45379)
                     /gene="pepA"
                     /locus_tag="TVW25_000183"
     CDS             complement(44312..45379)
                     /gene="pepA"
                     /locus_tag="TVW25_000183"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1377862.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPGHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            45724..46071
                     /locus_tag="TVW25_000184"
     CDS             45724..46071
                     /locus_tag="TVW25_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1377863.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            46068..46385
                     /locus_tag="TVW25_000185"
     CDS             46068..46385
                     /locus_tag="TVW25_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1377864.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            46400..47026
                     /locus_tag="TVW25_000186"
     CDS             46400..47026
                     /locus_tag="TVW25_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1377865.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(47329..48042)
                     /locus_tag="TVW25_000187"
     CDS             complement(47329..48042)
                     /locus_tag="TVW25_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1377866.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            48154..48549
                     /locus_tag="TVW25_000188"
     CDS             48154..48549
                     /locus_tag="TVW25_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1377867.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            48996..49970
                     /locus_tag="TVW25_000189"
     CDS             48996..49970
                     /locus_tag="TVW25_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1377868.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            49988..50950
                     /locus_tag="TVW25_000190"
     CDS             49988..50950
                     /locus_tag="TVW25_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1377869.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            51065..51949
                     /locus_tag="TVW25_000191"
     CDS             51065..51949
                     /locus_tag="TVW25_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1377870.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICATGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            51958..52761
                     /locus_tag="TVW25_000192"
     CDS             51958..52761
                     /locus_tag="TVW25_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1377871.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(52860..53864)
                     /locus_tag="TVW25_000193"
     CDS             complement(52860..53864)
                     /locus_tag="TVW25_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377872.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(54150..54791)
                     /locus_tag="TVW25_000194"
                     /pseudo
     CDS             complement(54150..54791)
                     /locus_tag="TVW25_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(54812..55789)
                     /gene="dusB"
                     /locus_tag="TVW25_000195"
     CDS             complement(54812..55789)
                     /gene="dusB"
                     /locus_tag="TVW25_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1377873.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(55776..56648)
                     /gene="hslO"
                     /locus_tag="TVW25_000196"
     CDS             complement(55776..56648)
                     /gene="hslO"
                     /locus_tag="TVW25_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1377874.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(56898..>58070)
                     /locus_tag="TVW25_000197"
     CDS             complement(56898..>58070)
                     /locus_tag="TVW25_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1377875.1"
                     /translation="HNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNTE
                     LTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELVG
                     YISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLEL
                     ENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLSI
                     IYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTNK
                     SVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYILK
                     EKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT        16763 a        10258 c        13140 g        17909 t
ORIGIN      
        1 atttaatata aaactaaaac tttctggatc tatatttaca tcggctgata taatagcaaa
       61 taaagcaaac aatgtattgg gatcactaat ttgtcctaat actgttttta acttaccact
      121 atctgattgt aaaacttgct caattttttt tacgtccgca ctcatatctc catacacaac
      181 tttatttcca agtagtcctg ttcctatcag gcttcctgtg atgagagtag ctgctagggc
      241 ttgatgacac aagcgtctga tgtttgattg tcttttcatg atttagtcct cacatatcgt
      301 cgaatgtttt ttctaaaatt cttccaaaaa atcttaacat gacgcttgca ggctgtgaat
      361 acgttttggg caattcgcct ccgtagtttc gtttttttta attcaatcat taaacgtctg
      421 attttatcat gatataattg atcttgttca aggctgatca ggaaattctt gatgaagatg
      481 acagctttat atcggtgttt gggaaaccat aagattggca aggctacgct gggcttagct
      541 gacattgttg cttcaaaatg ctttcaggtg tagaaatgtt gacaagtatt ctttaaaaag
      601 atagactata gctagtagga tagaggtatg cacaggtgac agatgtgata cttgtgtttt
      661 ttgctatttt tggaggtttc tgattgccta ttgcagctta tcaatatgaa agtgttgttg
      721 agattattag tgaaatcaat cgattacact attcattttc ttcgggttta ggagctcttc
      781 tatgctttaa tttgaaaaag agtgtcagtt cggtagtcgt taacaatcgt attgataggg
      841 agttccaaga gctcatcgtt tcttataaag caaggctaaa taggaatatt agtcaagtct
      901 caagcatacg acatcagttt ataggcatta gatggagaat aaagcaagca gaatctatta
      961 gtgagaagct tttatactac atgagcgaga atcatgagtt tggaaggatt cccttaaata
     1021 aatgtttgaa tgattttctt ggatttagga tcttggtcaa taacttagaa gttgtttttg
     1081 ctgctttgca aaatgataat cgagtgacta atattgctaa attgtattta agaacagatg
     1141 gcgactataa aggtatccat ctatatttta aaaatggaaa taatcggttt tttccatggg
     1201 aattacagat ttgggatcca gagcaatcac gcttaaatga gctgtcacat aaagagcata
     1261 agcaaaaacg acaatatata tcactacccc aacattattt tgatgctaat ttagaaaagg
     1321 aggaataacc gcatgtatca gcattttatt ttagttgcta gttcatatgc aagaggtgag
     1381 agagttggct ttcacttagc gacagaaggt caattggatc atgttgccat tgaagaaaaa
     1441 atgcagcggc tgagtcatat caatagagat gatgttggtg tgcattcttt tgttacagat
     1501 agtgctgatt ggcaaagtgt cattgagtta gattcctttt ttgaggatat tatggtttgt
     1561 caagacttcg atgaatttga acaggtttta caatccgact ctaaaattag tgctattgat
     1621 gttgctaaat ttttcttagc aatgcgtcca ctctcacact tacaattgca aaagttagtt
     1681 tatcttgctt ataaaacata tcttcttgcc tatggtgaat ccttatttga tgaaaaaata
     1741 gttgcttttc aatatggtcc tgtagtagaa gaggtgtatc acagctttaa aaaatatggt
     1801 tctgaggtga tagatatcga tgatcataca gaatatattt taaaagacat acatcttccg
     1861 caagccttag gtagaatgct attggtcgaa gacgcaaaga agattgtgcc tgtattatta
     1921 gatgttgtta aacagtatgg agatttaaca ggaggagaat tggttaagct gacgcactct
     1981 gaaaagggac cttggcagac ggtttttcgt ccacagttaa attgtgagat cactgatgag
     2041 gttattttag cccaaggcag atatgaaaga ttatcatcat aagtaccttt gcttattgta
     2101 ttagctgaga atactcagtt gtctcatcaa aaccaaaaca aaaaagcctt tgaaacgttg
     2161 atttcaaggg ctttctgtat atcgtcttat tttacctctg taaacacaac atgtttacgt
     2221 agttttggtg agtatttttt caattgaagg cggtctggag tgttacgttt gttttttgaa
     2281 gtaaggtaca agcgttcacc agattctttg tgttcaagtg tgatatttac gcgcatggta
     2341 tctcccttct attattcagc tgcgttagct ttagcgattt tatgtccttt gtagtatccc
     2401 ttaagtgaga cacgatgtga acgtgagtaa tctccagttg tttcgtcaaa ttttactgat
     2461 ggtgcagtca atttgtagtg tgtacgacgt ttgttctttt tagcttttga cgtgtgacgt
     2521 gcaggaactg ccattttttc tatcctccgt taaatgatca agggtctatt aaaagattgg
     2581 tgacaaactg gtgtgcatga tcttatgcta acctatctgt ctcaaatctt tgacccattg
     2641 ttatctattt gatgttatgg ctttcgccaa ctttagtatc atatcatatc ttctatgtaa
     2701 agtaaagtta cttgacaaaa attttattaa aaagctctgc tattctccaa aaatcctaaa
     2761 aaatggtaaa atgagacaaa ggtggttatt ttaggagatt aagatgtttg gaaaattatt
     2821 aagtctgtta ggctttgtcg ttgctttgac tggttgtggt gtttcacagg cagaaaaaga
     2881 acgtgttgta acagagtata gccccattat tattaaaaaa tttcaaacct taggatacca
     2941 agggaaaatc actgtagacg actatactaa gatgattgag acaggtagtg agagacttta
     3001 ttttacctac agcgaagaag tagacggtaa ggttattagt ctgaaggata gtatttcgat
     3061 tgctacctat aaatcacctg aggaagattt ggctgatgca gaagttgaca tgggaattag
     3121 ggaagaagct atgtggcagc aaccagctgt caaagcgcaa gctgctcaga tcaaacaact
     3181 atttagcgag ttggagactg aggatttgaa gcttatatcc gtaacaggac aaagtgtcca
     3241 gacgatttct gattcagatg gagagctgat tagggaagat gttgtacgag gcaggaatga
     3301 attatctcaa gatgcatcta ataatagaga agctgggcta tcaataggtg gctattatca
     3361 tattgatgtt tcaaagtatt tgaaaaatca cgtgttggaa attcgtatag attttgattg
     3421 gcgaatgtca gaagaggaac aagacgattt gtctggcccc aggttggatt tttctgatag
     3481 aataaaaagt ctagacttta cctgcttgtg ggatggctac tataaagtgg ggtttgacag
     3541 ggtgagtaga tctaatcgaa gtggagatat tcaagatatg attgttttag atattcgagg
     3601 cggtaaattg gttcgtagct tttctgtact ttaacagatt aatgaagcta ttctatggta
     3661 aaatatataa atactagtaa aagaggaaat aaaatgaagc ttcaaaaacc aaaaggaaca
     3721 caggacattt tgcctgtggc tgctgctaag tggcaatatg ttgaaggtgt tgcacgtgaa
     3781 acctttaagc aataccatta tggtgaaatc cgaacaccta tgtttgagca ttatgaggtc
     3841 attagccgat cagtaggtga taccactgat attgtgacca aggaaatgta tgacttctat
     3901 gataagggcg accgtcatat cacacttcgt ccagaaggaa cagccccagt tgttcgttcg
     3961 tatgtggaaa acaagctctt tgcgccagag gttcaaaagc ctgtcaagct gtattatatt
     4021 gggtcaatgt ttcgttatga gcgtccgcag gccggccgtt tgcgtgaatt tcaccagatt
     4081 ggtgtagagt gctttggctc tgccaatcct gccactgatg ttgagacgat cgccatggct
     4141 tatcacctct ttgaaaggct tggtattaaa gaggtgacct tgcatttgaa tagccttgga
     4201 aatgcagcta gtcgcgcagc ctatcgtcag gccttgattg attacctatc tccaatgcgt
     4261 gagaccttgt ccaaggatag tcagcgccgt ttagatgaaa accctctgcg cgtgcttgat
     4321 tccaaggaaa aagaggataa gattgcagta gcaaatgccc catctattct tgattatctt
     4381 gacgaggaga gtcaggctca ctttgatgct gtgcgcagca tgcttgaagt acttgctatt
     4441 ccttatgtta ttgataccaa tatggtgcgt gggcttgatt attacaacca cacgattttt
     4501 gaattcatta cagaggtgga tcagtctgag ctgacgattt gtgctggtgg tcgctatgat
     4561 ggtcttgtgg agtattttgg tggaccagca acccctggct ttggttttgg acttggtttg
     4621 gaacgtcttt tgcttatcct tgataagcaa ggcgttgaac tgccagtcga agaaggcttg
     4681 gacgtttaca tagctgtttt aggggcttac gccaatgtgg cggcgctagc cttgacacag
     4741 gccattcgcc gtcaggggtt caccgtagaa cgcgattacc tcggacgtaa aatcaaagca
     4801 caattcaagt cagctgatgc tttcaaggca aaggtagtca tcaccctagg tgaaagtgaa
     4861 atcaaaacag gtcaagctgt ccttaagcat aatcaaactc gtcaagagat gacagttagc
     4921 tttgatcaaa tccaaacaaa ttttgccagc atttttgcag aatgtatcca gtaaagcaaa
     4981 aaaactgaaa aaagtggtat gagtcattaa gatactaaaa aatcacacaa cgtcgttgct
     5041 ttaatagcaa tgatattgtg tgattttgtg atgttatacc tatactaagg actatttttc
     5101 ctatttttag tagtcagttt gaaagcactc ttgtttggaa tggcagcagc tatgcttata
     5161 gctggtgatg ggttaatgct attgttgaga aactaaaaca atgttagaga agataatgct
     5221 gactttatag atgttattgt ctatggtttg ctggtatagt ccataatact gttgaacaat
     5281 tttttgaaca tttttaattc ccaatccgtc ttttttccgt tgacttctgg aagcaagctc
     5341 ttttggatca aaaaagtttt cgatatcaat gtggagttga tttttaaaga gtctcacctt
     5401 taattgtatt tgtttttcag ctttattttg attgcgaata gttgcggcaa tgctattatc
     5461 aagtagattt cctataatga ctgaaataac ttcagtcttt aggcttatgt ttgtagggat
     5521 aaggcagtga atatctaaca caatgccatt ctttttggct acgactgctt tttgattaag
     5581 taaataattt aaaatagtat cattggtaaa gaaagtatct gtcccatcta gcaggttaag
     5641 gttatgattc agtaattgtt gggctttagt gtactgcttt tgctccagaa gtcctaatag
     5701 gacaatgttt tgattatgta gatcatgctt aagagcccta atgcttaatt gattttcctt
     5761 tacattttct aaatgcttca gttctgactg gaatcgtacc ctatctaagt taatgtcttg
     5821 catttgtaaa tgctgatctg aaatgtaagt atacagatac agcgaagtga ttgtgataat
     5881 gataaatcca agtgttagca gtattgtaaa caagtcaaat aaaggttctt cttttaatcg
     5941 aaggagctgt agcagtagca gagaaagact tatcattgga ataatagata gctttagtat
     6001 ccagttggtt tgtgtttgct catcaagcca attgtctgta gtctttaaaa agagctgctt
     6061 taacacaaat ataatgataa tactggatat ggtaagcagg tttataaata aaaatgtccc
     6121 actgatagaa gagatttgat atttaagaga tattaaaatg atccctaagc ttgcttctag
     6181 caggatacct atgctttgaa gtgtaacaga ccaaaagata cactgtttca tggagtaacg
     6241 atagctacta gatattatca gtgatgttac caaagaacaa gtcagggtta tcagtgaggc
     6301 atagcttcct gatacaaaaa aatgagtgca gcattctatg aatactaaaa aagagagata
     6361 acctatgttt ttaaaggtag ctagctgacc atttttctga cgaaaaaaat aattaacaat
     6421 cacaatatta acaactgatg tataaagatg aaaaatagcg ttaatagcca tttactctcc
     6481 ttagcttgga aaagatgttc tcctgaatac ccttcttaaa tttccgactg ataggaatga
     6541 taaaaaagcg cgtgttatca atagctaatg ttatgtcatt gttttcaaat ttatagaagt
     6601 aattgacgtt aaacacataa gaatgatggg tttggataaa ttgttcagga agctctttta
     6661 gtaatgcttt ggttgataaa aaggtagagt aggtcttgtc cttggtatga atgagtactt
     6721 ttcgtccttc cttttcaaaa tagataatat cgtttaagct taagctatag taggagtggc
     6781 aagatgaaaa ggtaaaaaat tttttgtcaa gctctaaaac ccttagagct ctatttaggc
     6841 actcaaaaaa atagggttca tttaaaggct taatcaggta atcaaaggtt tgcacgtgaa
     6901 aaatgttttc catgtattct ttgtggcttg ttaaaaagat aataatagca gagagattat
     6961 ctttcctaat atgctcggct aatgctattc cagacatgtt atccatttca atgtcaagaa
     7021 gaaaaatatg gtaatcatta gacagtgact gtattaattg acaaggatcc tcgtaaatgt
     7081 ctaactccac tggaactaat tgattatatt ggtataatag atcttctaca gctgttgcaa
     7141 aagctttatt gtcatcacaa agagcaattt taagcatggt acccccataa tcctatagac
     7201 tgtggtattt agtataccaa aaatgacatg aaaagcgcta ttttttacaa aataataata
     7261 atagactgaa tgttttgata aaatgaatct atgaaatgag ggagcaataa tgactgaagt
     7321 aacagtgcgt aaaccgatgg aaacaatgga agtttcatgg gtagtcattt aaatactcta
     7381 aagtgggctg tttttatcag cctactttaa tatttttagg agggtaaaaa atgaattata
     7441 gcagaccttg tattaaagat atttatccaa tttataaact gagtgatacc atgtttcgaa
     7501 taggcgctca aattaatatt acgacggaat ttaacgattc aaattatgaa acaggtgctt
     7561 catttacaca taagctttgg ccacatttca aagagtgtcc ggcttgtggt catggcaaca
     7621 gtaatgattg ggaaatattt agtcattatg ggtaggagtt aatcaatgga acaatatgaa
     7681 ttaatggtga ggtcactttc aaaaaggtat gccagagatg gctcttatgc caatagggat
     7741 ttacattgtg tctttaaatc cagtgaaata acagccttga taggtcataa tggagctggt
     7801 aaaacaactc tactaaacca gattattggt aatataaaac ctgatgtggg tgatatttca
     7861 tttctagact gttcgtttgt caagtcccct aaaattgcta gaaaaaatac gtcaatgatg
     7921 cctcagctac atgccccctt aaaaggaatc acaattaaac aggctatttc atcaattgga
     7981 aaaatcagag ggctgtccgg aaaattattg gagacagagg ttcaggaatt aattcaagaa
     8041 ctcggtctta ttaagtggca aaatactgtc ggagagaaac tctctggtgg actaaaaaga
     8101 ttgacgtcgt ttgcaatggc tgttattgct gctccgaaga ttgttttact agatgagccg
     8161 acaaatgatg ttgatcctat aagacgtata aaattatggt tatacttaaa aaagatggcg
     8221 gcaaagggac atatcgttat tgttgtcacc cataatattt tagaggttga aaaatatgca
     8281 gatgcttatt atttgcttga aaagggggaa gtaaaaagtt caggagcggt aaaaacccta
     8341 tccagcaatc caaagagtag aatatccatt ttatttagag atcaaaaagc cttggaagaa
     8401 tacccatttg cttactcact tggtggggat gacaatgaag ctataacaat aatggataat
     8461 aaggaaatga cagcattatt gaattggtta ggcatacatt tgtcatcaga taccattgtt
     8521 caatatagta tcacgacgtt agggttaaat gattattatg aggagctgtc agatgaagaa
     8581 gattagtgtt acttaccaat ttctaagctt gttaaattgg agctttattc gccataaatc
     8641 gttgatatta ttgtgtagcg ttattcaatt ttttatgaca attgcactgg tttacggtta
     8701 ttcacttatt attgctgatg atactgtgca aacagtctac tatcttgctt ctggctcagt
     8761 aacgattggt atgattacca ttggctgtac ggtatcagca caatcaatca gtagtgataa
     8821 aagagatggc attgtgagct atattcaaac gttacccgtc ctaagaagtt tgatcctgct
     8881 atctgatcta ttgatttgga cattaactgc tttgattggt gttggtgtgt caattgcggt
     8941 tgtttattta aaatttcaaa tattgcccca gctgtcctta gcgacgtttc ttattttgcc
     9001 attagtttta atgacaatga tcagtatggg ttttgccatt gcttattggt caactccaag
     9061 tacgatgatg ctggtaaccc aattattgtt gatgattggc ttattgtttt cacctataat
     9121 gtatcctgca gaacgtatac ctgaggtgat tttaagggga tatcattttc tgccatttat
     9181 accagcagga gacttgattc gagagacggt ttatttgggg cattccattt cagttgtcaa
     9241 gcttgtggtg ttactgttat ggctggttgc cactgcctta ctttcagtca attggctaaa
     9301 caggcaaagc taaggtatag gctctgctat ttcttaaaaa ctctactcaa atgggtgggg
     9361 tttttaattg ttttttgtta taataagtgg taatgatatt tttaattaga gaaaggaaca
     9421 aagacaggta gggagtgttg actctttatt tgctcttggt atcttattta tgaagcgtag
     9481 catgtatgca ggacacgtcc gaaaggaaca tattggaaga acgattgttt taaaaggttg
     9541 ggtaagtcgc cgtcgtgatt tgggcggcct tattttcatt gatttgcgtg atcgtgaagg
     9601 agtgatgcag ctggttatta atccagagga cgtttcaggt gatgtgatgg cgactgctga
     9661 gcgcttacgc agtgaatacg tgattgaggt ggaaggaagt gttgaggcgc gtcagcaggc
     9721 taatgataag ctagctacag gtgcagtgga gctaaaggtt tcaggcttga ccattcttaa
     9781 tacagctaaa acgacaccgt ttgaaatcaa ggacggtgtt gaggttagtg acgatacgcg
     9841 tttacgctac cgttatttag atcttcgtcg tccagaaatg ctggaaagct ttaagcttcg
     9901 tgccaagacg acgcatgtta tccgtaatta cttggataat cttggattta ttgatgttga
     9961 gacaccgatg ttgacaaagt caacgccaga gggagcgcgt gattaccttg taccaagccg
    10021 tatcagccag ggacatttct atgctttacc gcaaagccca caaatcacaa agcaattgtt
    10081 aatgaatgcg ggctttgatc gatattacca gattgttaag tgcttccgcg acgaagattt
    10141 acgaggagat cgtcagcctg agtttacaca ggttgacttg gaaacgtcat ttttatctga
    10201 gcaagaaatc caagatattg ttgagggtat gattgcaaag gttatgaagg atacaaaggg
    10261 catagaggtt aagctgccat ttccgcgcat ggcttatgat gacgccatga atcattatgg
    10321 ctcagataag ccagatacac gctttgatat gcttttacaa gacttgacag atcttgtcaa
    10381 ggagattgac tttaaggtat tttctgaggc acaggctgtt aaggcaattg ttgtcaaagg
    10441 acatgcggat cgctactcgc gaaaggacat tgataagctg acagaatttg ctaagcaatt
    10501 tggtgctaag ggtctggcat ggctgaaggt ggttgatggt gcatttactg gaccaattgc
    10561 taagttcttg acaggtgtga aaagtaagtt gacagagtct ttacagcttg agcataatga
    10621 tttggtcttg tttgttgcag acaccttaga ggtagccaac aataccctag gtgctcttcg
    10681 tacacgtatt gcaaaagagc ttgacatgat tgacatgtct cagtttaatt tcctatgggt
    10741 ggttgactgg cccatgtttg aatggtctga agaagaggag cgttacatgt ctgctcatca
    10801 cccatttaca ttaccaacag cagagtcagc ccatgagcta gagggtgatt tagccaaggt
    10861 tcgcgctgtt gcttacgata ttgtcttaaa tggctatgag cttggtggcg gaagccttcg
    10921 tatcaaccaa aaagacatgc aagagcgtat gtttagagca ctaggcttca cagctgagga
    10981 ggccaatgag caatttggct tcttactaga ggctatggag tatggcttcc caccacatgg
    11041 tggtcttgct attggtcttg atcggcttgt catgctgctt gctggcaagg acaacattcg
    11101 agaggttatt gcctttccta aaaacaataa agcatctgat ccaatgacac aggcgcctag
    11161 tctggtatct gaaaagcaat tagaggagct tcagcttcaa atagaacatc atgattaaaa
    11221 aaacaaccta taggaaaaga gtaaaatacc tgattaatag aggagccaaa aaaattggct
    11281 tgcttcatgc cgtaaaaagc atttccaagg agaagtatac agagaaaatt tcggcctctt
    11341 tactctatgg catattgtct agtatagctg ttaatttctt tttccaaccg ggccatgtct
    11401 actcaagtgg tgcaacagga cttgctcagg ttatctctgc catcagccac catttatggg
    11461 gctttgagat tcctgttgct ttagcttttt acgtgactaa cattcctctt ttagtcttag
    11521 cttggtataa gattggtcat aaatttacga tttttacctt tattaccgtt agtatgagct
    11581 ctttctttat ccaaatcatg cctcaggtga ccttgacgac tgacccactg attaatgcta
    11641 tatttggtgg cttggttatg ggtttgggga tcggtacagg cttcaagtct cgcatttcta
    11701 gtggtggtac ggacattatc agtctgacac ttagaaagaa aacaggaaaa gatgtcggta
    11761 acctttcatt gatgatcaat ggtgtgatta tggcttttgc aggactgttg tttggctggc
    11821 agtatgcgct ttattcgatg gtgactattt tcgtttctag tcgagtgact gatgcgattt
    11881 ttaccaagca aaagaaaatg caggcgacca ttgtgaccag ctgtcctgac aaggtgatcc
    11941 acatgattca taaaaagctg caccgagggg taaccagtat caatgatgct gaaggcacct
    12001 acaagcatga gcataaggct gttttaatta cgattctcac acgtgaggaa tatagtgaat
    12061 ttaagtggct gatgcttaaa acagatccaa atgcttttgt ttctgttgct gaaaatgtta
    12121 gaatcattgg tcgctttgtc gaatcagatg aagactaaga aataggtatc aatatgccag
    12181 ctaataagag cttaaagctt aaaaattgtt gttttattat tcttggctca gctatttatg
    12241 cctttgcctt tgtctacttt tacatggcaa atcgtattgc tgctaatggg ctagcgggac
    12301 tgacgcaggt tgctaatgcc ttgtttcaga tcaatccttc aataacgggt tatctgatta
    12361 atttgcctct cgtcctgttg ggtgcaaggc tctttggcag acgggcaatg gtgtatactg
    12421 tgaccggtat tttatcactt tattggtttg tttggctgtt tcaacagctc ccccttttta
    12481 ttgacttaga tcatgacaat ttagtagtgt ccttgctggc aggaattctt ggtggtttag
    12541 gtggcggcat tgtttttaga aatggtggga cgattggtgg ctcagatatt attgctaagc
    12601 tgatagagga taggtttggc ttgcagctca atcaagcctt attagggatt gatatttttg
    12661 tcattgtggt ttctttgacc tatatttcaa taccgcagat gatgtatgct ttgattgcta
    12721 gctttatgta tagtaggatt gttcatctgg tgcaaaatgg tggctattct gcacgcggaa
    12781 cctttattat ttcagattat tctcagacta tttcacaatt cattatggag gagctcggta
    12841 gaggagtcac ctatttacat ggtgagggtg cttactctgg tcgtgagaaa caggttattt
    12901 atgtagctct aggtcgatca gatgtacgag agctaaaggc ctttatagca caggttgatc
    12961 ccaatgcttt tgtttctttc tttgatgtta acgaagtcaa tagtccagaa tttattgcca
    13021 caaaaagtaa ataccataaa acgaaaaaaa gataaaggct ggaatatcac attcatagcc
    13081 tttgattatg ctaatgaaag cgcttggcta ttaagcttat tgtagtgtag ctattaaatg
    13141 gccgtccttg agctttcatc tggtacctaa caaatgtaat gaatagtgag gaaagtgaat
    13201 gacaaatctt gacaaatggc atcgtgtaag agagctatta ttaattgcgg tgggtgttgc
    13261 tatctatacc tttggttttg ttaatttcaa catggctaat gaattggctg agggtggcgt
    13321 agctggaatt accttgattt tgcatgctca ttttgggatc aatccggctt attcgtcact
    13381 tttatttaat ctgcctttat ttatgttagg ggctaagatt tttggaaggc gctccctagc
    13441 cttaacgatt tatggaaccg ttcttatgtc agtctttatc tggctgtggc aaaaggtgcc
    13501 tatggagctt ggtttagaga atgatatgat gcttgttgcg gttgttgcag gcttgtttgc
    13561 aggaattggt agtggccttg tttttcgata tggagcgaca actggtggga ctgatattat
    13621 tgcccgcatt gcagaggaaa agtttggtgc taagctgggg caaaccctgt tatttgtaga
    13681 tgccttggta ttaacagcct ctctcactta tgttgatttg aagcatatgc tctatacatt
    13741 agtggctagc tttgtcttta gccagatgat tagtgttgtt caaaatggtg gctataccat
    13801 tcgtggtatg attattatca ctaagcagtc gcaagccgcg gcgcaggcga tcttgacaga
    13861 aatcaatcga ggagtgactt atttaaaggg acaaggcgct tattctggtc atgattataa
    13921 tattatgtac gtgacgctca atccaacaga ggtgcgagag gtgaagcgta ttttagcaga
    13981 gctagatcca gacgccttta tctctattat tgatgttgat gaggtaatca gctcagactt
    14041 caagattcgt cgcaaaaatt ttgacaaacc aattgagaag gctttacaga aaaaatccaa
    14101 catgttaaaa taaagaaaat aagcagaaat aagaggttga gaaaagccat gattaacaat
    14161 taactcattg tcaagcacta atctatgatt aacagcaagg gattagtgtc tgctttgagg
    14221 cttgggaatc agggcttttt gtgtgcactt tttcaggcct ttctgatgat agaaaggaat
    14281 aaatatggaa gcacttagta ttcagcatta cgctttagat acagcagaaa aaaacttatt
    14341 gacaatagat tctcttacat tgaatcaagg tgagagggtt ttcatcattg gtgataatgg
    14401 ggctggaaag accagctttt taaagacaat tatcggagaa agcactaact atagtggctt
    14461 tttgcaggtg catggagata ttgcttatgt tccgcaaatc aagtccacta gccctcagtc
    14521 aggaggtgag agggcgatgt cttacctaaa agaggctttt caagcaaggc cttctctgtt
    14581 aattttagat gagccaagct cttatttaga ccatgctaat cgtgattggt tgattaatca
    14641 attgaaacgc taccgaggaa ccttgctggt ggttagccat gatcggtatt tgatcaatca
    14701 attgagtcag aaaatatggt tgcttgagca tcaaacgatc aagacttacc atggcaatta
    14761 tgatgattat cagcgttcta gacagctaga ggaggataag cagctaagag cttttctgga
    14821 ataccaacga aagactaatc aactgaaaaa aagcctgacc agaaaaaaag tgcaggccaa
    14881 caaaatggct gtaaagaaaa agtcggtttc tcggtcagat tggaaaacca attcctttgc
    14941 gggcagctat gattcacagg ccaaggctat ggcaaaagca gctaaagcta tggaaaatcg
    15001 actcactcga atgaaagagg ttaacagtcc gcgcaaaaag gcttgggcaa aattaaaaaa
    15061 ggatccaaac gaaggtgcac taccaaatac tcttttacac ctacaagaag gtacccttac
    15121 aagggaccat cagttattgt ttgactatcc tggtattgtg atcagatcac atagcaggat
    15181 agcgattatc gggagaaaca aggctggtaa aagcagcttt ttagatcagc tggcagccca
    15241 ggccttgtct ggattttatg cgcaaaatct aaggataacc tattttaaac aggaccaggc
    15301 tgacttggag ccggatcaga cagcagtaga gctcattagt cggcagtcca gccaagatag
    15361 ggtcaccatt ttaaattatc tagctatgat gggcattgat tatgataagg ccaatcaaaa
    15421 ggtagctgtc ttatctggtg gggaaagggt tcgtttggcg ttagtggctg ccttgctgac
    15481 agatcatcag cttttgattt tagatgagcc gacaatttat ttggatcttg tcgctattga
    15541 ggctttggag tcttgcttga ttgactatcc agctgctctt ttgttggttt ctcatgacct
    15601 agcatttgtt aacaaggtag caacagaaat ttatgaggtt aaggatcatc atttaacagc
    15661 ctatcatttt gaagactagc aaaaaagcct aggctagctt atcctcgcta gcttaggctt
    15721 attagtctac atttcatttg gtgcctcaac acccaataga cgaagcgctt ctttgaggac
    15781 gattgcagtt gcatagcaaa gcgctaagcg gttgtcacgt tctggatcgt cttcgaggat
    15841 acgggtatgc gcataatatt tgttaaagct ttgtgccaag tgaatagcaa attttgccat
    15901 gattgatggc tcaaagttat caaaagcacg cttgatgata cgtgggaagt cctggataag
    15961 cttaatgatt tcccagcttt caggatcatt aaggctatag cttgtatcgg tagctggcgt
    16021 aaagcttgct ttacgcagga tagattggat acgtgcgtgt gcatattgga cgtaaggacc
    16081 ggtttctcct tcaaaggata ccattgcttc aagatcgaag tcatagccat tcatacggtc
    16141 tgtttttaaa tcatagaact tgatagctcc cacaccaaca gcatgagcta ctgcttcctt
    16201 gttggcaagc ttaggatttt tagcttcgat ttggtttgct gctctgctga tggcttctgc
    16261 aaccgttggc tcaagcaaaa tgacattacc cttacgtgtt gataattttg caccgccctt
    16321 tgtcacaagg ccaaaagcaa cgtgtgtcat gtcatctgac caatcgtagc ccatttcttt
    16381 aagaacagcc tttaattgct tgaagtgtgc agcttgctcg ttgccaacca cgtaaactga
    16441 ttttgcaaaa tcataggtac gcttgcggta aagggcagca gctagatcac gagtaatata
    16501 aagcgtagct ccatctgatt ttttaatgag agctgggtgc tcaataccat atttttcaag
    16561 gttaaccacc ttagctccct tagattcgac tagtaggcct ttgtcctcaa gaagctcaag
    16621 gacctcatcc attttatcat tgtagaaggc ttcaccatta tagctatcaa agctaactcc
    16681 tagctggtca tagagtcggt taaactcaat caagctttca tcgcggaacc actgccaaag
    16741 ctctgtagcc tcttgatctc tctcctctag cctgcggaac cattcacgtg cctcctcatc
    16801 aagactagga tcagtttctg cctctgcatt gattctcaca tagagcttta agagctcatc
    16861 aattgggtgt gcttgaacag cggcctcatt tccccacttc ttatacgcta caatgagcat
    16921 accgaattgc ttgccccagt cacctaggtg attgatttta acaggcttat agcccatttt
    16981 tgcaaagata tgagcaagac tgtccccgat aactgttgag cgcaggtgac cgattgaaaa
    17041 tggcttagca atgttagggc tggacatatc aatagcaata tgacgtcctt gtccttcatc
    17101 ctgttgagca tagtcagctc cgtcagcaat cacctgtgta agaacctgtg cagaaatgct
    17161 agccttatct aaaaagaaat tgacataagg accaacagca gcaaccttct caaattggct
    17221 ggcgtcaatc ctttcagcta aatcactagc aatagcttgt ggtgctttgc gaagcgcctt
    17281 tgctagacta aaggctggaa aggctaagtc tcccatgtca gaatttttgg gtgtttcaag
    17341 taagttaaaa atggcagcct gctctagttc aggaacaatc ttagcaatct cagctgcaat
    17401 cagagtttta gtgtccatat tgcttctcct aaaaatagtt tgtcacccta ttctaacaca
    17461 tttcttggaa ataaacgagg tgtctattga gaaattatac tagaaggctt gtaggtgttt
    17521 tggggaacaa agctaaagaa ttagagcagc aaagcttgcc aaatctaagg gtctaatgat
    17581 atgagcaaga aataatgctt ccttaaaata aagcaaattg acagagctga gatgaaatac
    17641 taccattttt ttgttataat ttgagaggat aattatacat tggggagata tatcatgaat
    17701 aaaatagaac ggcagcagca aatcaagcaa cttattcagg ctgagcacat cggtacacag
    17761 gaggagatta gacggcttct tcaaaaggat ggtatcgtgg tcactcaggc taccctatca
    17821 cgagatttaa gagaaatcgg attacttaaa ttaagagatg acagaggtaa gctatactat
    17881 agtctttctg agcctgttgc cacaccattt agtccagatg tgcgctttta tgtcctaaag
    17941 gttgaccggg cgggctttat gctggttctc cataccaatc tgggagaagc agacgtgttg
    18001 gcaaatctta ttgacaatga tgccattgag gacgttttgg gcacgattgc gggtgctgat
    18061 accttacttg ttatttgtcg tgatgaggag attgccaagc gctttgaaaa agatttagct
    18121 gctggtctat aatatgcctt accgcgaatc cttacatcag ctgatagcag cactggaaaa
    18181 gcactcaagc attatagctt ataaggaggc tcagcagcac ttgcttcaaa ggactgatta
    18241 taatcaaaag gcctatcaga tgaagcgaca tcaacaggac acctatcttt ttcgtcaaat
    18301 cgctaaggat aaagcagctg aagaatcagc ttttaaggct cagcaattac gagaagattt
    18361 agatcatcaa ccattgatag atgattatcg tgacaaaatg caaaacgcta gtgacttggt
    18421 tcggtacatt acagggacta tagaagatga attaaataag gagttcaatg atggcaaagg
    18481 ctaatgtttc tcccggaatg cagcagtatc tggacatcaa aaaggattat ccagatgctt
    18541 ttttgctttt taggatggga gatttttatg agttatttta tgaagacgct gttaaggcag
    18601 cgcagatttt agaaatcggc ttaaccagtc gtaataaaaa tgctgacaac ccaattccaa
    18661 tggcaggtgt tccctatcat tctgtccaac aatacatcga tgttttaatt gatttggggc
    18721 ataaggttgc tattgctgag cagatggagg atcctaagca agcggtcggt gttgttaagc
    18781 gtgaggtggt tcaggtcatt accccaggga cagctgtgga ctcaagcaga cctgatagtc
    18841 ccaataattt tttggtggct gttgattttg atggcaaggc ttatggcctg tcttatatgg
    18901 acgtctctac aggagaattt tttgctacag acctagcaga ttttgccagt gtcaaaagtg
    18961 agattcaaaa cctgaaggca aaagaggttc ttttaggctt tgaattatct gaagaagagc
    19021 aggctatttt agtaaagcag ctgaatcttt tgctgtcctt tgagatgaca gcactagagg
    19081 attcgccttt gattgatcat cagctaacag cagtcgagct gtctgcagca ggtaagctgc
    19141 tacactatgt tcatcaaacc cagctgcgtg agcttagcca tctacaggcc ttggtgcact
    19201 atgatattaa ggattatttg cagatgtctt atgcaaccaa atcaagcctt gacctgcttg
    19261 aaaatgctcg tactggtaaa aagcatggga gcctttattg gttgcttgat gaaaccaaaa
    19321 cagccatggg tatgcgtcta ttaagggctt ggattgatag gccacttgtg actagtgagg
    19381 cgatcctaga acgtcaggaa attatccagg tgtttcttaa tgcttttatc gaaaggacag
    19441 atctaagcga tagtttaaag ggtgtttacg acattgagcg cttgtctagt cgtgtatctt
    19501 ttggaaaagc aaaccccaag gatctattac agctaggtca tactttggcc aaagttcctt
    19561 atatcaaggc tatcttagag gcctttaaca gtccttacct tgacaagctt gtcaaccaaa
    19621 ttgacacttt gcctgagcta gagcacctga tacggtcagc tatagatcca gatgctcctg
    19681 ctactatcaa tgaaggcaat attatcagaa caggctttga tgaacggctg gatcattacc
    19741 gaaaggtcat gcgagaaggc accggctgga ttgctgatat tgagacaaaa gaaagacagg
    19801 ccagtgggat aagcaatctc aaaatcgact ataacaaaaa agatggctac tattttcatg
    19861 tgaccaactc taatctaggt atggttcctg accatttttt tagaaaggca acattgaaaa
    19921 attctgagcg ctatgggaca gcagagctag ctaagattga aggacaaatg cttgaggcta
    19981 gagaggagtc atctagcctg gaatatgata ttttcatgcg tattcgtgct caagtggaga
    20041 cctacatcga taggctgcag cagctagcaa aagctctagc aactgttgat gtcctacaaa
    20101 gcttagcagt ggtcgcagag aagaatcact atgttcgacc attatttaat caagagagca
    20161 agattgcgat tgacaatggt cggcatgctg ttgttgaaaa ggttctaggt gttcaggagt
    20221 atattccaaa cagcatttcc tttggtccac agacaagcat tcagctcatt acaggaccaa
    20281 acatgagtgg gaagtctacg tatatgagac agcttgcttt gacagtcatt atggctcaga
    20341 taggctcatt tgtagctgca gaatctgcta gcctgccttt atttgacgct atttttacta
    20401 ggattggtgc agtagatgat ttgatctcag gccagtctac attcatggtt gagatgatgg
    20461 aggctaatca tgctatcaag cgagcaaccc ctcattccct gattttgttt gatgagttag
    20521 ggcgtggtac agcgacctat gatggtatgg cactagccca gtctatcatc gaatacattc
    20581 atgatagagt tggtgcaaag actatgtttg cgacccatta tcatgaattg acagagctgt
    20641 caaccaagtt gacaaagctg gttaatgttc atgttgcgac gttagaaaaa gatggaaatg
    20701 taaccttcct gcataagatt gccgaaggtc ctgctgataa atcctatggg attcatgtgg
    20761 cgagaatagc tggattgcca gaggatttac tagccagagc tgatactgtg ctaaccaagc
    20821 tggaagctca atcacaagca agagagtccg tcttatcaac tacagaagta agagagactc
    20881 agcagctggc taatcagcag ctatcacttt ttacagatga tggctcctct agcgagatta
    20941 ttaaaaggct tgagagtgtt gatgtgatga atctaactcc cattcaggcc atgaccgttc
    21001 tttatgagct aaaaaagcta ctgtaaaagc tagtatcaga tgttaaaggc acttgtaggc
    21061 tcaccaggcc acaggtgctt tttggtttat tgaccataag acccttgcta gctctgatgc
    21121 ttggctcttt tagttttatg ttataatagt ccataagaat gcgaggaaat atatgacaac
    21181 aattatcgaa ttacctgagg ttctcgccaa tcaaattgca gctggtgaag tcattgaaag
    21241 accagcaagt gttgttaaag aattggttga gaacgccata gatgcaaaga gtagtcagat
    21301 tactgttgaa atagaagagt ctggcttgaa aatgattcaa atcactgaca atggcgaagg
    21361 gatgtctcac gaggacctgc ccctgagcct gcgtcgtcat gccacaagta aaatcaaaag
    21421 tcaaagtgat ttgttcagaa tcagaacact tggctttcga ggagaagctt tgccttcggt
    21481 tgcctctatc agtaaactaa cgatcaaaac agcaacagct gatgcagagc atgggtcaat
    21541 attagttgct agtggcggta agattgagca gctggaagct gtctcaacac ctgttggtac
    21601 aaaaatcaag gtagaaaacc tattttacaa tacaccagct agactgaaat acatgaagag
    21661 cttacaagcg gagctggctc atgttgttga tgtcgtcaat cgcttgagcc tggctcaccc
    21721 agagattgct tttacattga tcagtgatgg caagcagcta acacaaacct ctggggctgg
    21781 ggatttacgt caagcgcttg ctggtatcta tggcctgaat actgctaaaa aaatgattga
    21841 catttctagt gctgatttag attttgaagt gggaggcttt gtgagtctgc cagagctgac
    21901 aagagctaat cgtaattaca ttactatcct gatcaatggt cgctatatta aaaatttctt
    21961 gttaaatcga gccattttag atggttatgg ctctaagctg atggtgggac gctttcctat
    22021 agctgtcatt gatattcaaa ttgatcctta tctggcagat gttaatgttc acccaaccaa
    22081 gcaggaaatt agaatttcta aggagcgtga attaatggct ctgattagta cagctatttc
    22141 agagagccta cgagaacaag acttgattcc tgatgccttg gaaaatttag ctaggtccag
    22201 cacacgttca ttttcaaagc ctgagcagac cagtttgcct ttacagccta gtcagcttta
    22261 ttatgatccg caaaaaaatg atttctttac caaagaaaca gtggtttcag aggatagccc
    22321 gcagggcttt aaccatgaaa ctttggttga cagtggtgtc aagcaggttg acaatttgca
    22381 gctggccaag actgaatctg aagcagctgc tccaagtgtt aaatatgcta gtcggccaga
    22441 tcctatgctt tctgatggtg agcacccggg tcttgatgtc cacaataagc aaaaattatc
    22501 tcagatgctt gatcgtttag aaaatgaaga gcagtcggtc tttccagagc ttgattattt
    22561 tggccaaatg catgggacct acctttttgc ccaaggcaga gatggcttgt ttatcattga
    22621 tcagcacgca gctcaggagc gcgtcaagta tgagtattat cgtgacaaga ttggtgaggt
    22681 tgacaatagc ctacaacaat tgctggtgcc ttatctgttt gagttttccg gatcagattt
    22741 tattaatctt caggaaaaaa tgtcgctttt gaacgaggtt ggtatttatt tagagcctta
    22801 tggcaatcat acctttatcc ttagggagca ccctatttgg atgaaggagg cagagattga
    22861 atctggtgtt tatgaaatgt gtgacatgct gctgttgaca aatgaagtat ccatcaaaac
    22921 ttatcgtgct gagctagcga ttatgatgag ctgtaaacgt tccatcaagg caaaccatag
    22981 cttagatgat tattcagcaa gacagctgct tttacagctt gctcaatgta aaaaccccta
    23041 taactgccca catggtagac ctgttttgat taacttcagc aaggcggaca tggaaaaaat
    23101 gttccgtcgt atccaagaaa atcacaccag cttgagagaa ttgggcaaat actagagagg
    23161 atagcatgcg agaatttttc cagttaccta agcaaataca aattcggcaa tttgtgcgct
    23221 ttattaccat tacgcttggc agtagtatct ttccttttat ggcgatgtac tatacaagct
    23281 actttggcgc cttttggaca ggcatactaa tgatggtgac tagctttaca ggctttattg
    23341 ggaccttata tggaggtcat ttgtcagatg ctattggtcg taagaaggta attatgcttg
    23401 gttcagttgc gagcacctta ggctggctgc tgaccatttt ggccaatgtt ccaaagacgg
    23461 ttcttccttg gttgaccttt gtgggaattt tgctggttga gcttgcttcc agcttttacg
    23521 ctcctgccta tgaggctatg ctgattgatt taacagatga tagcaatcgt cgctttgttt
    23581 ataccattaa ttactggttt attaatatag ccattatgct tggtgcaggt atttcaggac
    23641 ttttttatga tcggtatttc ttagaactgt tgattgcttt actgattatt aatatcgtct
    23701 gctttggtat tgcctatcgt tattttggtg aaacgaggcc tgagcattac cgctttgagc
    23761 atggtattgg tattctagca ggttttgcta actaccggca agtctttaag gatcgcgctt
    23821 ttgtgttatt tactataggg acgattttat ttagcagtat ttggttgcag atggacaatt
    23881 acgttccggt tcaccttaag ctgtattttg aagagactga tgtgctcggt attcatctga
    23941 ctagctcaaa aatgctgtca ctgatggtct ttaccaatac cttgctgatt gtgctgttga
    24001 tgacagttat taatcgcttg acagcaaggt ggagattatt accacagctg gtgatcggat
    24061 cggttatttt tgcctttggt atgctgttgt catttacatt tactggcttt tttgctattt
    24121 ggtgttcagt tgtggtgttt accattggtg aaatgctaaa tgtccctgcc aatcaagtgt
    24181 taagagcaga aatgatggat cagtctaaaa ttggctccta cacaggcttt gtctcgatgg
    24241 cccagccttt gggagctatt ctagcaggtt tgctggtttc tcttagtcat tttacaggac
    24301 aggctggtgt tcagctagca tttgttttga ttgcctgtgt ggggctttat gtgattgttt
    24361 tatctgcgaa aatgaagaaa aaggtgtagt atgtacgatt atattaaagg tcagctaaca
    24421 aaaattactg caaagtatat tgtggtagaa gcaaatggtt taggctatat gataactgtt
    24481 gccaatcctt atagctttac agactgtgtc aaccagcagg taacgatcta tcttcatcag
    24541 gtgatcagag aagatgctca gctgctgttt ggttttcaca gtgaggaaga aaaggacgtt
    24601 tttttgaagc tgatttcggt atcaggtatc ggaccgacga ctgccctagc tattgtagct
    24661 gtagatgata atagaggact cgtcaatgcc attgataata gtgatattac atatttgatg
    24721 aggttcccta aaatcggaaa aaaaacagct cagcaaatgg tgcttgattt agcaggtaag
    24781 ttcgttgaag cacctaagga ggaaagcagc aagcccccta aagccaagca acaggggaat
    24841 gaacagcttg atgaggctgt cgaagcccta ttagcccttg gatataaggc gacagagcta
    24901 aagaaaattc gagccttctt tgagggaaca agtgagacag ctgagcagta tatcaaatca
    24961 gctctgaaaa tgctaatgaa aggctaggag cttcatatga aacgttgcgc atgggtacca
    25021 caagataata agctttattg tgattaccat gacttggagt ggggaaggcc tgtctatgat
    25081 gatcgcgctc tttttgagct gctttgtctt gaaagctatc agtcaggctt atcttggtta
    25141 actgttttga aaaaacgtcc agccttcaga agtgtttttc atcattatga tatctcagct
    25201 gtggcaagct ttagtgagca ggaaatggct gctgccctgc aaaatgcagc aattatccga
    25261 cacaagccaa agctaatagc cactgtcaac aatgcagcgg cagtccagcg catccaacaa
    25321 gagtatggta gcttttccag ctatctttgg aactttgtag gaggtcagcc aattgacagg
    25381 cttgtcaacg atgacaaccc agcgcccgct caaacagccc tatctctcaa gctatctaag
    25441 gacttgaaaa aacgtggctt taagtggcta ggaccaacaa ctgtttattc ctttatgcag
    25501 gcagcaggat tggtcaatga ccatgaagag aactgtgagt ttaggtagaa ttaatcgcct
    25561 ctttggagtg atgtttcatg agcctatcaa agagagcttg ataaaaacag cccaatcttg
    25621 attgcttata ggatgatgta taagagctat gtttttgctc cgtactttaa ggatagatga
    25681 tgaatcccct tatttaccct gtagcgaatg ttgtaagctt ctaatgggtt taaggtttta
    25741 gcctgttact gctattgcca gtaagctaca gtttgatcag gtagttatat tggattgcct
    25801 caacgattgt gttgctgctg gctggtgctt ctttctataa cttattttgg tgcatgtgat
    25861 tgtggctcta aaagttataa cagagtatcg gtacgattgg tgttacccct tggtttctat
    25921 ttttttctta tcagccagtc tggcatttac agcctataat aaaagctacc gcttaaaaat
    25981 ttcttagcgg tagtttttta gttcatgttg caaggtttct agaagttcag tttcttctgt
    26041 caactgtagt aattgtaagc ctttattaat taggtgatca tcattacgac aaataccgag
    26101 acgaacttgg gaaaaaccta agctatcata gcgtttaagc tgtctagcta atttgattgt
    26161 tagtaaggta atttcttcgc actccttttt gaggttgtga tagaggtaaa tggttgaaag
    26221 attggttagt aaagcatatt cagatgattt gatattgcgg taatctttat attttgctag
    26281 gctatctagg attttttgac tgatgttttc aattatttcg ataggaaagt gaaaaagaat
    26341 ggtatgtagt aattgtaaat ctttctcata ccaagtatct tgttttacga gggaattcca
    26401 gattttataa gctagctctt gtaaatcttg attgttttta acgccttttt tcctaagact
    26461 tatcatgact tcgacactat ctaaaatata agaaatggga atatcatttt tatttttaag
    26521 gtaattgaag catttttgac gtaatttttc taattcagta atatttacag ctgatacctg
    26581 attataaaat tggtttaaaa tgtcctgcct tgtgctagga tgataagtgt tgcagacata
    26641 tctaaactct tccagtgtca tattgagttg gtttaataaa aaaatcattg tatcaaattt
    26701 aggaatgact tgtccgcttt caatacgagc tagtgtagaa cgagctaaaa agtctccaca
    26761 gatcttttct tgtgttaatc ctttagattt tcgtatagct tgataaattt taccgtaatc
    26821 ccaacgcata aaacacctct aaaatgttac taaatgctac aaaaaaataa aatctacaat
    26881 agtattttat aatagcattt agaaagagta aaggaggaaa atttatgagg agacatctaa
    26941 aggttgtatt attacttgca gcactattgg catttattgt aaatgagggt aattttccat
    27001 ggtggccttg gggaccatag tacttaactg attactgtta tgttgttgcc attagactat
    27061 ctagattaat caaagagtaa aatacaagta gcttagtgaa agacatttta agaggagaaa
    27121 agcatatgaa gaaacgttta gcatttatat tagttgcttt tggtattttg ggatttagtt
    27181 taggaaatga agttttagct gcagatactg cacctgcaag tgcaactatg gcaacagata
    27241 gtgatgtgag tttttacaat ggagaactgt tgaaaaaata tttggtccaa agtggtgata
    27301 gattgtattt tgattatgac aaagctattc aagataaagt ttctgatggt gtaatagata
    27361 tgggattcct tgttgagaca attagtgagg actattcaca acaaacgttt acctctcgaa
    27421 agtatttcaa ggcaggatgg cagctttatg gtaattattg tggacctggc cataacggaa
    27481 atcattttac tttacctgtt attgatgttt tagatcaagg ctgtcaaaat catgacagtt
    27541 gttatcgatg gggagctggg attggtgcaa attgtgaatg caatcgtcag ttagtaaatt
    27601 acattaaagt atatcgacgg tggatgccag ctcatgcctt gggggttgct gatgctatta
    27661 gagtatattt tgaaacggta ggtgctattg gatgttaacc ttaaaaaata ttatcaatcg
    27721 atactacatg tattatgtat tccttattgt tgtgatctgg attgggatgt tttttgtacg
    27781 atgggatact actgtggctg gtgtattact ctatccactg attatgaagc aggtatttat
    27841 cgtactagga gtagttgcga tgataatggc cattatttct agaaaaattg ttcttggaat
    27901 ttttggttta ctatgctgtg ctgctttttg gattaatctt ttcttagctt tctatctatt
    27961 acctggactt ttgggaaatt agcgattaaa ctgtttttga tgttttgaag atgagaaaca
    28021 gattgttttt ctgtaaggct tcctgttact tctcaaatgc tttggagtat ctctttatca
    28081 tttgttcact gttgacaacg ttaaaaagat tattccaaac atgggaattg ctgcttcagg
    28141 gtattccttg ttaatattgg attgattagt tgttatttat gcaaaatcct tagagcattg
    28201 ctttctcatt cttggttcat ttgaataaaa tgtaactaaa aaaactttgt aatcaattca
    28261 aattgtcaca agtataaaag taaaaaagcg actttgttag tgatctgata ttcggaagtc
    28321 ctatcattgc tcgctttttg ttttttgagg ttgattttta ttccgaaatt gttgtgaata
    28381 agtgcaattt taagctaaga attacctaaa atcttttgaa gattactgct tagcttctaa
    28441 tacctattta tcggtgtgtt gataattgga gagatagcgg gattgtcata tgaaataaat
    28501 tttagaaaat ttaaacaagt tattctgatt attattattt caacataagt ctttatttga
    28561 ttatcattga aaaccattaa ttcatctaaa attatttcaa tgcttcatgg atgattcttt
    28621 ttttgttaaa atgagattga atgtcgaata gataagtagg tgggaaaatg aaagctgaac
    28681 tcattgcggt gggaaccgag attctgactg gtcagattgt gaataccaat gctcaatttt
    28741 tatcagaaaa aatggcggag cttggtattg atgtttattt tcaaacagct gtaggagata
    28801 atgaagagcg tttgctttct gttattgata ttgctagcca gcgaagtgat ttagtgattt
    28861 tatgtggtgg tcttggtcca acagatgatg atctaacgaa gcagacctta gctaagtatc
    28921 tgggaaaagc tttggtcttt gatgagcagg caggtcaaaa attagatgct ttttttgcac
    28981 atcgtaagca ggctgctagg acaccaaata accaacgtca ggcgcagctg attgaaggct
    29041 ctattgcttt gcaaaatcaa acaggacttg cagtaggtgg gttaataact gtagataggg
    29101 taacctatgt tgtcttacca gggcctccaa gtgagctaaa gcctatggta aaaaatgagc
    29161 tggtgcccct tctttcagct agtcatgcca gtctatattc aagagtgctg cgtttttttg
    29221 gcattggtga aagtcaactg gtgactgctc tggaggattt gattaagcat caaacagatc
    29281 ctactattgc tccttatgca aagaccggcg aggtaacact gcgactatcc acaaaggctg
    29341 acaaccaagc attagctgat gaaaggctga atcgactaga ggcgcagctc ttatccataa
    29401 gaactgtaga taatcaaccc ttacggcgtt tgctttatgg ctatggggag gataattcct
    29461 tggcgcgtga gacctttgag ctattgaagc gaagtggtaa gacgataaca gcagctgaaa
    29521 gcttaacagc aggactgttt caagctcagt taactgattt tgcgggagct tcacaggtgt
    29581 ttaacggtgg ctttatcacc tacagcattg aagaaaaagc aagaatgctt ggcattccat
    29641 tgggtgagct acaaaggcat ggtgttgtga gctcttttac agctgagcaa atggctgcac
    29701 aggcacgctg cttgaccaat tcagatatcg gtattggtct aacaggtgtt gctggtccag
    29761 aggcactcga gggacagcca gcaggaacag ttttcattgg ccttgccact aagaataagg
    29821 tagaatctct taaagttgtt ataggaggcc gtagccgttt ggacgtgcgg tatattgctg
    29881 ccctatatgc ttttaatatg gttcgtaaaa ctttattaaa atcagagaat ttgctataat
    29941 taggatagtg tattttagga aattagtaac tagacagatg tgaggttatg ctgtttattg
    30001 cttgctagtc agcctaaata gaggagaaaa tattggcaaa aaaagttaaa aaaaatgaag
    30061 aaatcaccaa aaaatttggt gatgaacgtc gtaaagcact tgatgatgcg ttaaagaaca
    30121 tcgaaaaaga ttttggtaag ggtgcggtta tgcgccttgg tgagcgtgca gagcaaaagg
    30181 ttcaggtgat gagttcaggc agtcttgctt tagacattgc gcttggagca ggtggctatc
    30241 ctaaagggcg tattattgaa atctatggac cagagtcttc tggtaaaaca acagttgccc
    30301 tgcatgcagt agcgcaggct caaaaagaag gtggtattgc agccttcatt gatgcggagc
    30361 atgccttgga ccctgcttat gctgcggcgc tgggtgttaa tattgatgag ctgcttttgt
    30421 cacagccgga ttctggtgag caaggacttg agatagcagg taaactgatt gattctggtg
    30481 ctgttgattt ggttgttgtc gactctgttg cagctctagt gcctcgtgct gagattgatg
    30541 gtgatattgg tgataaccat gttggcttgc aggctcgtat gatgagtcag gcgatgcgta
    30601 agctttcagc ctcaatcaat aaaaccaaga caattgcgat ctttattaac cagctgcgtg
    30661 aaaaggtagg ggttatgttt ggtaatccag agacgacacc aggtggtcgt gctttgaaat
    30721 tctatgcctc tgtccgtctg gatgttcgtg gaacaacaca aataaaagga actggagatc
    30781 aaaaagacag tagtattggt aaggaaacca agattaaggt tgttaagaat aaggttgctc
    30841 cgccatttaa ggtggctgag gttgaaatca tgtatggaga aggcatctca cgtacaggtg
    30901 agctgattaa aattgcttca gatttagaca ttattcaaaa ggctggtgct tggttctctt
    30961 ataacggtga aaaaattggt cagggctctg aaaatgccaa gagatatttg gctgatcacc
    31021 cagagctgtt tgatgagatt gaccataagg tgcgtgttaa atttggcttg cttgaagata
    31081 ctgaggaaag tgcagctgca gatacagttg cagccaaagc agatgagttg gttttagagc
    31141 tagacgatgc cattgaaatt gaggattagt gcttagtatt agattttcag ataaaggtgc
    31201 taaaaagggc ttaacagcga tcgtcaagcc ctttttagct tgtgtttaat caagctctgt
    31261 attggtctgc tcaggagcta ggctgtacgc ttggataatt tgttagctga gtttatgttt
    31321 tctttaggga ttaactgtta agctataaaa gccctagaaa aaagggactt cctacagaca
    31381 agatagtggc atagtaagct tgcttgcaac tagctcaata taggattttg gccttggtta
    31441 aagggatcat aaaagaaaac taaaaaatag gtccaaagac cgatattgat tagaaaaaaa
    31501 ctatgctaca atagaggtat cacgagatag aaagtgagaa caacatgata aaaatttaca
    31561 cgatttcaag ttgtacgagc tgtaaaaagg ctaaaacctg gctgaatgcc cataagctcc
    31621 catataaaga acagaattta ggaaaagaac ctctttcaag agaagaaatt ttagctattt
    31681 tatcaaagac tgaaaacggt gtggagagta ttgtctcttc taaaaatcgt tatgccaaag
    31741 ccttaaattg tgatattgac gagttaagcg taaatgaggt tattgatttg attcaggata
    31801 atccccgtat tttaaaaagt ccgattctta tcgatgacaa gcgtcttcag gtgggctaca
    31861 aggaagacga tattcgtgcc tttttacctc gttctattcg taatattgaa aatgcagagg
    31921 cgcgtttacg cgctgcctta taaaaagctc tgtcagagct ttttttaata tcctaacaaa
    31981 tctgaattct tgtttattca ataaaaataa gctataatag agcgtagcac ttaaagttag
    32041 aaagaaggtg taagtatggg atttacagat gaaacagtcc gctttaattt agacgatggt
    32101 gataaaaagc agattagcga aacgctgacg gcagtttatc attcactaga tgaaaaaggc
    32161 tacaatccga ttaatcaaat tgtaggttat gtactaagcg gggacccagc ttatgttcct
    32221 cgttacaatg atgctcgcaa ccaaattcgt aaatatgagc gcgatgagat cgtagaagag
    32281 cttgttcgct attatttgca aggaaatgga atagatatta gatgagaata atgggacttg
    32341 atgtcggttc taagaccgtc ggtgtggcaa ttagtgatcc acttggtttt actgcccaag
    32401 gactagagat tattaggatc aatgaagata aacaggattt tggctttgat agattagctg
    32461 agcttgttaa gcaatatcag gttgatcgat ttgtcattgg cttgccaaag aatatgaata
    32521 acactagtgg cccacgtgtt gaagcaagta aggcttatgg agataagatt gaggagctct
    32581 ttcacattcc ggtttcttat caagatgagc gcttgacaac tgttgaggca gagcgtatgt
    32641 tgattgagca ggcagacatc agtcgtggta aacgtaaaaa agtaatcgat aagctggctg
    32701 cgcagctgat tttacagaat tatttagatt gtaactatta aggagaacag atgacacata
    32761 atcatgatca cgaacacgaa gtcattacac ttgtcgatga gcaaggaaat gaagcattgt
    32821 ttgaaatttt attaaccatc gatggacgtg aagaattcgg taaaaactat gttttactag
    32881 ttcctgctgg ttcgcaagag gatgaatcag gagaggttga gattcaggcc tattcattta
    32941 cagaaaatga agacggaaca gagggtgatt tacagccaat tccagaggat tcagacgctg
    33001 agtgggatat gattgaggaa gtctttaata gcttcttaga cgaagagtaa caacctgagg
    33061 cattagcttt aaaataataa atagcctaga atcttggtgc tagcagcatg ggttttaggc
    33121 tatttttatg gtttatcaga cagtaggagt gatagctatt tctatgacct ctaaatagcc
    33181 tactgttaag agtgttttta gggtcttgta gatgttgcaa tagcctgtaa tttcgttgaa
    33241 gttacttgct gttgtctttt ttagtttaag ccttaacaaa gcttatagga aatgactcaa
    33301 cttagcacag cataagccgc ttattttgat aagtaaagaa atagccaata gctactttta
    33361 gcttaaagct gatcattacc agtaccctta gcttttctgg gtattatttc gaataatctt
    33421 aatgggggtg attttatcaa aagactcagt caagaagaaa aaagctttct aaagcattat
    33481 aggctaaaga cactgcaccg ctttaaagag ctgctgactt atgccagcat ttgtcataaa
    33541 ttgactaaat aatagatttt gctatacttg taatatgaca tgtcaaggag aaacacattg
    33601 agtcaattac atcaagaagt tatgctggaa aaggtcaatt atttggtgaa agaccaccca
    33661 tcgtcacata cgactaagta tgacatgaag gtccctagtt tatataaatt ttatatcttt
    33721 ttctttagca tcatagcgag cttgcttacg gttgcggttc ctttttttgc agatactgca
    33781 aatagcgttc agtcacaaaa tttatacatc ggaatgatgt tgactaaagg tcagattcca
    33841 tatagtgact tgtttacaac aggaggcttt ctgttttttg tgctcatagc tttgagctat
    33901 cacttgggaa caacggtatg gttggtactt gttcaagcgc tgtgctttta tttgacaggt
    33961 gtttatttct ataaattaat ccattatgtg acaggtattc agaaggtggc tttaggtttt
    34021 acagctatct attacctatt gtctattagt cttggatttg gtggcttata tgcgatccag
    34081 cttgccctgc cttttgtctt ggtatcgctt tggtttttaa ccaagtattt tgctggcttg
    34141 gtaaaggacg aggcctttat tctctttggc tttgcagcgg caatagccat gctaattgag
    34201 cctaggacgc ttcttttttg gctgcttgcc tgcattgcga ttattgctta taatgtgtct
    34261 caaaagcatt tcgctcgagg cttttatcag ctgttagcag ctatttttgg aatgcttttg
    34321 gtgttttata cagcaggcta ttttatcctc aatttacaga ttttgagtcc ttatttggag
    34381 caggcgcttg tttatccgtt tagttatttt gtgacaggtg atttatcgct gattctcggt
    34441 ttaacagtcc aattaggact tgttcttggc ttgggactgt taacggggct gctgacgttt
    34501 atgaagcagc ctaagctaga gtctgatctt gctatgaaat ggctactagt ctttgttgtg
    34561 tttagctatg ctggtattgc ggctatatcg catgattttc atacttatca cctactgcct
    34621 ttactgcctt atgctttgat cttgctatca agctctgttg gccgacaata tgaggcagga
    34681 cttaggatgg ttagtcatcg tcgtcgtaag gggaaaaatg gtgcgagacg ggttattgct
    34741 atttatctaa ataagcattt ctacgtgcca gcaatcataa tgctaggagc ggtttttggc
    34801 acagcttatc agtatgtgac cagctctgct attaatcaag agcgttctca gattgctcac
    34861 tatctaagac agaggctaac ggaggaccaa cccatctatg tatgggacga tacgtcaaaa
    34921 atttacctgg aaacgcaggc caagtcagct tcacagtttg cctcaccctt tgttaatctg
    34981 aaaaaagaga gtcatcaaca gatgttagag gatgagctac tacagaataa ggcagtctat
    35041 attgtggtca acaagcaaaa agcattacca aaggcagtca agaaaatagt gacagctaat
    35101 tataaaattg acagaaagat tgatgttaag ggctttagcc tatatcagaa aaaataaata
    35161 aaatcaatat attgtgttgg tataaaaaaa cttaacacaa tatattgatt tttttgtgtg
    35221 gcgtgatata atagtcgagt aaggagatag gacatgataa cattagaaaa agacaaagtt
    35281 attgttcagc cagctattaa ggttattaaa agagatggac gcttggttaa ttttgatgca
    35341 acaaagatct acagtgcgct gttaaaagca agcatgaagg taacacgcat gtcaccgctc
    35401 gttgaagcaa agctagaagc tatttctgaa cgcgttattg cagaaattat cgagcgattt
    35461 cctacaaata ttaaaattta tgaaattcaa aatattgttg agcatgagct attagccgct
    35521 aatgaatatg ctattgctaa ggaatacatc aattatagaa cccagcgtga ctttgcccgc
    35581 tcgcaggcga cagatattaa tttttctatt gataagctca ttcacaagga tcagacagta
    35641 gtcaatgaga atgccaataa ggatagtgat gttttcaata cccagcgcga tttgacagct
    35701 gggattgttg gtaagtctat cggtttgaag ctgctgccag cgcatgttgc taatgcccac
    35761 caaaaaggtg atattcacta ccatgattta gattatagtc cttatacgcc aatgacaaac
    35821 tgttgtttga ttgattttaa gggaatgctg gcaaatggct ttaaaattgg gaacgctgag
    35881 gttgaaagtc ctaagtctat tcaaacagca acagctcaaa tttcacaaat cattgctaat
    35941 gtggcctcca gtcagtacgg tggctgtaca gccgatcgta ttgatgagtt tttggcacca
    36001 tatgctgagc taaatttcaa aaagcatatg gctgacgctg aaaaatgggt tattgaggag
    36061 ctgcgggaaa gttacgcctt tgaaaaaaca aaaaaagaca tttatgatgc catgcagtct
    36121 ctagagtatg agatcaacac gttatttacc tcaaacggtc agaccccctt tacctcattg
    36181 ggatttggtc tagggacctc ttggtttgag cgtgagattc aaaaggctat tttaacgatt
    36241 agaattaatg gcttaggcag cgagcaccgt acggcaatct tccctaagct catctttacg
    36301 gtcaagcgtg ggctcaattt agagccagac tcaccaaact atgatattaa gaccttagcc
    36361 ttggaatgtg ccacaaagcg catgtatcca gatatgttat cttatgataa gattattgag
    36421 ctgacaggat cctttaagtc accaatgggc tgtcgctctt tccttcaagg ctggaaggat
    36481 gaacaggggc aagatgttac ctcagggcgt atgaaccttg gggttgtaac catgaattta
    36541 cctcgtattg ctatggaatc aaatggcgat atggataaat tctgggagct gtttaacgaa
    36601 cgattacaca tttgtaagga cgctcttgtt tatcgtgtag agcgcgttaa ggaggcaacg
    36661 ccagccaatg ctcctattct ttaccaatat ggagcctttg gcaagcggct agctaagact
    36721 ggcaatgttg atgagctctt taacaatcgc cgcgcaactg tatcattggg ttacattggc
    36781 ttatatgagg tagcaaccgt attttacggt gggcaatggg agcacaacca agaggccaaa
    36841 gactttacaa tcactattgt taaggaaatg aaaaaggctt gcgagacttg gtcagatgaa
    36901 tatggctatc atttctctgt ttactcaaca ccatcagaaa gcttgacaga tcgtttttgc
    36961 cgcctagata ctgacaaatt tggcgttgtt gctgatatta cagataaaga atactatact
    37021 aattcattcc actatgatgt tcgtaaaaat ccaacacctt ttgagaagct agattttgaa
    37081 aaggcttatc cagcagccgg tgcttcaggt ggctttatcc attactgtga gtaccctgtt
    37141 ttgcagcaaa atcccaaggc cttggaagct gtttgggact atgcttatga tcgtgtgggc
    37201 tacctaggca caaatacgcc aattgataag tgctatgaat gccattttga gggagatttc
    37261 accccaacag agcgaggctt tacttgtcca aattgtggaa acaatgaccc taagacagta
    37321 gatgtggtta aaagaacctg tggttattta ggaaaccctc aggctcgtcc aatggtcaat
    37381 ggtcgtcata aggaaatctc tgctcgtgtc aagcacatga acggatcaac catcaagtat
    37441 ccggggatat aagccttgga gaataatctc attacaccta tatcattgta aaggattgct
    37501 tcatgcaagc agtcctttag ttatcaagac aggtctgtaa caaagaaagg gagaaacatg
    37561 ggaaaatacc agttagatta taagggaatg cagcaagtag agaggtttca tgagaaacat
    37621 tctgttgcaa aaacagacaa aaagtctcga gtacagcagc ttagagcaca atttttagaa
    37681 aaagcaaagc aatcaaagaa ataatggcac actcagtaaa ggcggtgaag aatgctagat
    37741 attggaattg ttgggttagg cgctatttca caaaaggcct atttacccta tatgcgtcaa
    37801 ttaagaggaa tcaattggca tttatctact agaaatgcgt tagtccgcca ggaggtgggt
    37861 cagctttttg gttgcgcaag gctttacagc actgtcaatg agttacttga ggctaagtta
    37921 gatggtgtgt ttatccatgc agccactaag gctcatttag agctggctag tttgttttta
    37981 caaaaaggaa ttccagttta catggataag cctttgacgg aggatttctt tagcacgcag
    38041 gctctttatc aattagcaga taagcacaat acctttttga tggcagactt taatagacgc
    38101 tttgcacctg gtgtcaagaa gttgtcaacc ctgtcaacca aacgtaaagt tgttgttgag
    38161 aaaaatgata ttaatagacc aggtgacaaa cagtttaagc tttttgactt ctttatacac
    38221 cctttagata cagctttatt tttagttgat aggaggcttg ttgcaggcta ttttcattat
    38281 cagctgactg ataatgattt gctaagtcag gttagtgtaa ccttaaggac agaacagact
    38341 attatttcag cagctatgaa tctacagtca ggtagcaggc gtgaggtgat ggaggttcag
    38401 acacctaaag agacctatca cctagaaaat ctagagacct tgcgagctta tcgaggggtt
    38461 gatcaagaga tcaagggatt tagtgcttgg gatactacct tatctaaacg aggctttgag
    38521 gctattgtgg attctttttt acaggctgtc aaggatggtg ttaaccctgt caagccagag
    38581 acaagtctgt tgagtcactg gatttgtcac caaatttgtc aatctcatga agctgatggc
    38641 atattagatg tttctcttcc cttataaagg agtgataata tgaagctacg aagacctaaa
    38701 aagcaagatg aagcgtctgt tttagaaatg atggcagagt ttgaagacta tcagtctcct
    38761 catgatggtg gtttttggaa cgctgagcat tttgattatg aaaaatggtt ggaatctaat
    38821 gctctgatgg aggctggctt agctatccct gagaattggg tgcctgccat acagctcgtt
    38881 gcctttgctg atcaacaggc tattggattt gtcaatgtac gcttgagatt aaacgaacag
    38941 ctactggtaa aaggtgggca tattggttat tctgttagac ctagccagcg tggaaagggc
    39001 tatgcaaagc tgatgctaaa ggaagccttg cagcttgctc gtcaaaaggg cattcgtgag
    39061 gttttagtga cttgtcattg cagcaatagt gctagtcggt ctgttatttt agctaatggt
    39121 ggtcagctga aggattgcaa taagggtatt gaacgctatt ggataaaagc ataagaggca
    39181 ataatgaagg aaaactgttg gaattctccc aaaccaaaag aatggacatc agaggcatta
    39241 agccaaggac gcgttattga ttataaggca tttaattttg tagatgggga gggagtgcga
    39301 aactcacttt atgtttcagg ctgcatgttc cattgtaagg gctgctataa cgcagcaacc
    39361 tggtctttta aggcgggtat tccttatacg aaagagcttg aggagcaaat tatgactgat
    39421 cttgcaaagc cctatgttca aggtttgaca cttttgggcg gtgagccctt tttgaatacg
    39481 ggaatattga ttcctttgat taagcgtatc agaaaagagc tgccagaaaa ggatatttgg
    39541 tcttggacag gctatacctg ggaggaaatg atggaagaaa cccaggataa gctagagctg
    39601 ttaagcatga ttgatatttt agttgatggc cgctttgata tcaccaaaaa gaatctgatg
    39661 ctgcaatttc gtggatccag taatcagcgt atcatcgatg ttaaaaagtc actggctgct
    39721 ggagaggtgg ttatttggga taagctaaat gatggtgatc agtcctttga gcaaatgagc
    39781 cgcgatgatt tgatttagta gagacttatc aacatcacta gacttgaaag ctaataatga
    39841 aagcatgatt ttaggctcct gtggtcttgc ttaaccaatc taataagggg ttttccccac
    39901 attatcctca tacttatcca caggttgtga ataacctgtt ggtttgtgga taaaaaagag
    39961 aattaagggg ttctttaatt ctctaggcct gaaaaagggt tctttttgat gttttttctt
    40021 aaaagaaaga gaggcaagtg acctctcttg aaatagtata cttaggcttt aagcctagct
    40081 ttcaatatct ctgaatgtct gattttctta ggagtcaggc attttttaat ggcgatggga
    40141 agtacggctt gtgggtcgct ttgtgtgcta agaggctttc tgagctgcta tatgtcaatg
    40201 attggtgatg tgacagctga ggcttgttca cattctgaaa gcactgatgt ttttcctagc
    40261 tttctttttt gatgtagtag taattagttt cggttgatag ctcctcatta tagcaaaagc
    40321 cagcaaagct cagctgctta agtgcttcct tggtttggac attgttttct agacaggctg
    40381 ttagaaaggc tcctcgagct ttttttgaaa tggttgaatg cgtcttgagc tgtcctgatc
    40441 tttcctccat aaatttggga cttatccaca gtttttgata ttcctttgaa aaaacatctc
    40501 taaactcgtt ggataacaga gaaatgattt gcttgtgatc tttagcaaac tgatcgtaga
    40561 tagggcgcca ataatgctta aggctttgcc cattgatggt tactttagtg tgaaaatcat
    40621 gccggtgctc tgcgattttc tcatcagtag ggataatgcc ataaaaagac gaggtaatgt
    40681 agacctgctt tgagaggtag tcttgctggt ctttagagag attgtcgcgc ttgagatgac
    40741 ggtacatgag cccattaaag agctgataag caggataagc agaactctgc ccttgagcta
    40801 tggcctttag tctcttggct tccttgcttg ctgcttctat acggatgctg taggcccttg
    40861 ctagctcctc tagggatagt tcagccatag cctctaatat gggcaggctt ttttggggaa
    40921 gctgatgtgg atagcaaggt ggaactggtt tcatttcttt agctgttgga attaaaaaag
    40981 ttaacataag tttattgtag taaaggcggc aaccttctgt caagagtggg atacatttgg
    41041 tggttatgtc atatgaaact aatttttata ttttttacat tttgattagt ttttaaaaat
    41101 atagtgattt agtgttgcat aacctctcta agtatgttaa tatatactta agtctgtttg
    41161 ataaacagaa gctcaggtca agtgagtgtt ccacttacaa taacgcagtt gatgatgggg
    41221 agactcagac tcagagtcaa ggaaaagaaa tatagtcttg taggattacc tacagggctt
    41281 ttttctattt tgaattgaga gatcaatata aggtgatgtg ctgtttttta ttaccttaaa
    41341 catttggata ttggctattg acaaaaagtg taaaggaaac tatactatat gtgtaaagtt
    41401 aacttgacat attggaggaa ccatggaaaa tcggatacaa gaactccgta agtcacgagg
    41461 gattagtcaa gctgatttgg cagatatgat gtgtgtcact aggcaaacca ttatctcctt
    41521 agagaaagga cgctataatg cgtcattaga gctggcctat aaattagcga catttttcaa
    41581 tctgactata gaagacgttt tcttgtttga agagaaggga gaatgagatg atatttagtg
    41641 atttaagcgt cctgctgact caaaaaagcc agctagccta tgccaaaagg ctgaagtata
    41701 tgggcttttt cgctctctgt ttaggcggtt tgtttttgtt gctggccttt gacgtgagac
    41761 tgacgagctt tgctcaggga atgctggtag ggcttggtag tggtagctta ttattaggtg
    41821 ttcgtgcttt ttcagattgc ctttaatcct caaaggctga gagcctctta tattaaggct
    41881 tatgatgagc gtcatcaggt agttatcaag ctagctgctg tatcaacctt aatcttatta
    41941 gtggtgttga ttattggctg tttgtgcttg aatgtttttt ggagtttggt ttttggcttt
    42001 agagtatttt tagagatttg tctgtatacg atcttgcttg gttttttagg catcaagcta
    42061 ttgttagagc atatgattta ggaggcttca atggaaacaa aacattcagc agtaaaggtc
    42121 atcatcagta aattaaaatg gtttggctta gctcttcttg tgtttatgct tgagcaggct
    42181 ccaacatttt tgataacaaa agaacagcca atgtggcaga cacttcttct tgtggtcatt
    42241 tttcttttga ttagtggagg tacttattac ctagctgtga agcttcacat tgtgggagat
    42301 caagctattc ctaagaatga ctatcgggca ctttggattg gtttgggagt ggtagctgtc
    42361 tttgttgtca agatgattgg tggtattctg ttgtttttgg agcatggtcc gggagccaat
    42421 acggtcaatc aagctgcctt agaacaggca ggcttatctc cgattcttat ggttacgcta
    42481 gttgctattg tggcaccaat tgtggaagaa attgcttttc gagggctgct ttatgggaag
    42541 ctctttggtg cagagtctta tctgggcttg atttttagca gtatcatgtt tggcttgatt
    42601 catgtgccaa cagattttgg cagttggttt atctatggcg gtatggggct ggtgttaggc
    42661 tttgttttcc ataaaacaaa gaaggtcgaa tacacgatat tgattcattt tttgaataat
    42721 gcactagctg ttcttatcat gcttttgctg ccttatcttc agtagtactg cttgagtaat
    42781 gaagggggta atgaatgaaa aatgatcgtt ggattgacaa aaaatatcaa cgttgggaga
    42841 aagtgtataa gagacttggt cattctttac tgacaatcgg tgtgttggta gggacttatg
    42901 ggattttttt gattattcaa gggaatcatc aaacgggctt tctccttttt atcctggggc
    42961 ctatactatt gattgcgtca tgtctttgct attatgtgtt tacagagcca acgtctttac
    43021 gagaatatct gattaatagc tatgatgagc gtaaccgagc tattcgtcag aaagcacagg
    43081 cctactgctt ttgtctattt gcttttctct ttttgatgct tgcgatattc tttccaaata
    43141 tgacgatcaa ggagcttttt gggtataatc ttccgttgat tgttttcaat ctgtatgtca
    43201 tgattagagc ctgggttagt aaacacatgt aggtcatgtt aacacaaagg agtctagagc
    43261 aagggctttg aatgaaacta tttttctaaa aacgcaaaaa atcgcgtgca gtaacagatt
    43321 aggccatgtt actgcatgcg attttgttgt ttcaaacgtg agctcagaat gacatatcct
    43381 ttttagaaag aataggtatt tagggctgtc ttgagctagt cttaggtaat gagcttggag
    43441 ctcattggtg atggttagga taggtcttta gcttttttga tcgttgtgtc aatggcagag
    43501 cagacagaat gtgtcaggcc tgttttttca agatccatca agcctgcaat ggttgtgccg
    43561 ccgggactgc agatcttatc aatcaaatca tggggactat ctgtgctgac tagcaggttc
    43621 ttggcgctag ctaggacagt ttgactaacg atactaaggg ccttgtcttt aggcagtcca
    43681 tttttgactc cggcctttgc catagcttcg atgaaaaggt aaagataagc aggacttgac
    43741 cctgctagag cagtaaaggt atcaaaatcc ttttcagcta tttcaaaggt tgttccaaag
    43801 ctgttggtta gctctttagc agtagctaat aaatcagcag ttactaagtc attaccagtc
    43861 aaagcagtgg tgctttggag aatttgagca ttcatatttg gcatgatacg taggagtggc
    43921 aaatgagagc ttgttaattg agctagtctg tctaaggaaa taccagcagc cattgacatg
    43981 ataggctgtt tgaactgtag agggctaaga acagtctcaa agagctgtgg cttgatccct
    44041 agaatgatga agtcaacctg atcgatcagc tcttggtgag attgggcgta gcttaggtgc
    44101 aattggccag caatttcttt agagcgagct aaggatgagc ctgagatgat tagctcgtgt
    44161 ggtgtgtgtg ttaggccttg aatgatagca gttgccattt tgccaacacc gataaatcca
    44221 attttcataa taatgttcct aaaaatgaat aaaggctcaa taggctagag tgctcattga
    44281 accttagatt cgcattttag ccttatcctt cctagtattt cttgattaaa tcaactgttg
    44341 agcggtcaag ctttttgaca atggcttgca aaaaggcctg tgcttctacg aaatcatcta
    44401 aggcgtacaa gctctgatgt gagtgaatgt agcgagcgca gacaccgatt gtggttgaag
    44461 ggataccgcc atttttaagg tgagcagcac cggcgtctgt accgccttta ccacaataat
    44521 attggaaggc aaccccagcc tcctcagcgg tggttaatag gaagtctcgc atgttcttaa
    44581 gcatgatgtg tccgggatcg taaaagcgta gaagggttcc atcaccaata tggccaggat
    44641 tgccataaat atcaccagca ggtgagcaat caacagcaaa gaaaagctca ggatcaaatg
    44701 tagtggctga cacatgggca ccacgaagcc cgacttcttc ttggacattt gctccagcaa
    44761 taagggtgtt gtgaagtgtc tggtctttta gggcttctag cagctcagtg accatgagaa
    44821 caccatagcg gttgtcccag gcctttgaga tgatattctt tttattggca gttaaaatgg
    44881 tttcagactg cggtacaata atatctcctg gtgtgatgcc aaagctttcg gcttcagttt
    44941 tgtctgtaaa gccaccatca aaaacaatat ctgaaaccgc tggcagacta gcagcaccat
    45001 ttgccccgcg cagaaaatgg ggaggaactg agcctgaaat aacaggaatg gcttggccag
    45061 cgcgagtgta taaggtaaag cgctgtgagc taacaactag tggattccag ccgccaattt
    45121 caacaacccg cagtgttcca tcagctttaa tctcgctcac cataaagcca acctcgtcca
    45181 tgtgagccgc aacaagaatg cgaggagctt gatccgcctt gctttctttt atcccaaata
    45241 tgccgccaag tccatcaacc tccactcggt caacaagcgg cgtgatctta gcgcgtaagt
    45301 aatcccgaac agtgtgctcg tagccggcga tgccgtctaa ttcagtaact tctttaattt
    45361 ttgaaaataa atcaatcatt tgtatactcc atttgtcatg taagattaaa ggtatcacgt
    45421 ctgcctctat tctatcattt tttagtgaag aatgggaaac agcttgagca taggaaaaga
    45481 gtttgggaga ttaggtgtgt ctttcttgct tgataagctg cttattatca gtttgattca
    45541 gatgagataa ctgctggtat tgatggaatg aaacagctat gcacaacagc cttgacaagg
    45601 atcgacaggc ctgagctgtc ttatgctatc aattgcactt aggtagagca gtagcctgat
    45661 attgatgtga ttagttgctc ttgtcaggtg gtttattagt atttcctaaa gtgtcagcta
    45721 gtcttggctg agattgttag cttttgctct agcctattat tccctttttg tgataaaatg
    45781 aaaggtatga atggaaaaaa gacacgtatt gtttcaggat taattggact gggtctgcta
    45841 gccggcttgg gattgaggct taaggaagtc tatcaagaaa gagagcgtca gagagtattg
    45901 gttgaattgc gcgccttttt ctcagcctta ggagagattg aggtcttgta catcaactcc
    45961 tttagctcaa agcgtgatga tgtcactggt ggccttgtca tgacagatgg taagacctat
    46021 acttaccatt accacaaagg aagtattgat tttaaagagg atttgacatg attattccaa
    46081 catctaagga agaacttgct aggctaattg agacagagcc taggctggtt ttgtttttta
    46141 cagcagattg gtgtccggat tgccagtata tctatcctgt aatgcctgag ctagaggctg
    46201 aaaacccgga tatgaccttt gtccgccttg atcgcgatga ttttatcgat ttagcgcagg
    46261 attggcaaat ttttggcatt ccaagctttc ttgttatgga aaaggggcag gagaagggcc
    46321 gtttggtcaa tagattacga aaaacaaagg ctgagattag tgactttcta gcagcctatc
    46381 actaagagga gaaaatgaga tgatttttgc atataataaa gagcaggtcg gtgatgtttt
    46441 gatggtgata ctagaggata aaaaagacat caagcgacag gttgagcgta aggggagagt
    46501 agcgcgtgtt tttgcagaag agacagggca aacccttgct tggaatattt ttgaggcgtc
    46561 agccttaatc gctgttgagg gaaatgggca ggttttcttg tctgaggagg agttagcgat
    46621 tttaaatgcg gagcttgctc aagaagggtt tactgaacga ttagaggcta gcccagcccc
    46681 tgtttttgtt gtggggcaaa tcattgagat gattcctcac ccagatagtg atcatttgaa
    46741 tatctgtcag gtacagattg ctcctgataa ggctgtgcaa atcgttgcag gagcacctaa
    46801 tgctgctgtt gggttaaaaa caattgttgc cttgccaggt gctatgatgc caagtggcag
    46861 ccttattttt ccaggaaagc ttcgtgggaa ggaaagcttt ggtatgatgt gttctccacg
    46921 cgaattggcc ttgccaaatg ctccacaaaa gcgtggtatt attgagcttg gtgatgctgc
    46981 agcggttggt gaagcctttg atcctgctaa gcattggcag agctagcagg acttgatcag
    47041 cattaaaatg gtgtttagtc cttcttttgc ttggtgaaaa gcctttggac cttgagccat
    47101 gcagtgcttt ttgctggtct gtgactgtct ttagcttcag gatcgaagca ttagagtagc
    47161 tgcttaactt attgtcagcg ctgttgattg cagtagcgct atgcttgtga caagtgaagg
    47221 caaagcctat caatgccctt ggctagggct aaaaattgtc tttagagtca cttttgaggt
    47281 gagtagctcg ctaatttcgg tattgaacgg tgcttaggta ccgttttttt aagctttgct
    47341 gagtgtgaca tgctgaaaaa aggccatgtc tttatatggc ttttggtcac agatggctaa
    47401 ttcaatcgtc cgcaacactt ccagccaatc aggcttagct ttaacctcat ttggttgaag
    47461 tccgtagcat gtccgcagtc cacgatagcc ttggagcttc aaatcggtct ttctgagtaa
    47521 gtcatcaata ctgtaggtct gacctgctgc aaaggataaa ctttcaaagg cttgtccatt
    47581 tagcacatta agtgccttgt catagtcgtg ttcaaaaata acagagtgga gaacttttcc
    47641 gacttgattg tgcttgatga gtgatagctg ccctttaggc ttcaatagac gttccatctg
    47701 agctaggtag atcgcatgct cttttggggc gatatattct aagacattgt ggcatatgat
    47761 catatcaaag gcttgatcag gcagtttttc tagcgcttct aatgaacctt ttattttatg
    47821 aatgctttct tgcttttggg caaataatag gtcaggattt ggctcaattg cagttacttc
    47881 attctggacg gctaatgcct ctgctgtgat gcaaaagcct gctccgaaat ctaaaatagt
    47941 cttgcctgct atggggccta attgggcaaa gatcaaatca tacatgagct ttccccaggg
    48001 ccttgtgagc atgtcttgat aggctttaag attaatagtc attatctagt tttcctttct
    48061 ttagctgctg tgagctattg gcaggatttc taaacttcac agcttgtcct tattttacca
    48121 tgttttacga ataataagat aaggaggtat gacatgtaca ataaagtaat cttgataggc
    48181 cgtttagtgg ccaagccaga attaaacaag acattaacgg ataagcaggt cgttcgattt
    48241 accttagcag ttaatcgtcg gtttaagacg acgactggtg agcgtgaggt ggattttatc
    48301 aatgctgttg cttggggagg tttggctgaa accttggctt cctatgctag caaggggagt
    48361 ctgctgtcac ttgatggcga gcttcgcaca cgaaaatatg acaaggcggg tcagactcat
    48421 tttgtgacag aggttttgtg tcattctttt caattgctgg aaagtcgagc gcaacgagct
    48481 atacgtgaaa acaacgctgc taatgatttg attgatttgg ctttagagga ggaaaagctt
    48541 cccttttaaa gacagctgct agcttactgt cgctaaggga gtcagacact agcattgtgt
    48601 atgctagaga tctcaacata atctaaaaaa tggcaacgat tctaaaaaaa atcttgacac
    48661 gtcttagaaa aaggtttaca atgtatgaca attaaaatga aagaaaacag gaggtgctgg
    48721 tatggtagca gttagcacag ctcagacgat gactaagcgt tattacttta gcttctttag
    48781 atagtgtttg tagacatgag cgcatggata caaacacact gaacgttatg tttgtatcta
    48841 tggggctaag ggctatttga gttgtttgtc cacatagatg atatctcttc taagtggaca
    48901 ccatacagca tgtattttgt tatctcatga tacctgtata ggaccattta gattatctag
    48961 atggtcttat ttttatgcaa gaaagaggaa atgacatgag atttaaacag ttatccttaa
    49021 cagcctttat agggcttttg gcaatgctgc taacggcttg tcgacaagaa accaaccaaa
    49081 cacatcaagc tgctagagtt gggattattc aatatgctga gcactcagcc ctagatgctg
    49141 cgcgtgaggg ttttattgag gcgcttgagc agggcggctt tagagagggg aagaacctga
    49201 ccattacaac caaaaatgca cagggtgatc aggctaacct gcaaacaatg gtggagcagc
    49261 tggcgggtaa gaacgatttg cagcttgcga tcgcaacgcc ggcagcgcag gcgcttttaa
    49321 atatggactc agagacacca gctgtattta cagcggtaac agatcctgtc tcagcaggtc
    49381 tggttgatac attagctaag cctggtggga atatgacagg ctctacagat gcgactgatg
    49441 ttgagaatca gattgatttg ttgaccaagg cgctgcctca agctaggaca gttgggattt
    49501 tctacaattc aagcgaggtg aattcggaga tacaggctaa gaaggccaag agggagcttg
    49561 agaaaaaagg cttaaaggtc cttatgaaaa ccgtaaccac tactaatgat gtgcagcagg
    49621 ttatgacaag cttggctagt caggttgacg ctgtttacct gccaacagat aatacggttg
    49681 cctcaacagc tactactatt ggggatattt taaaggaggc caaaattcct tcaatgggaa
    49741 gcgatgctgc ttacctgagt gctgttttgt tcacctcagg tgttgattac catgctattg
    49801 gcatgcaggc tggtcagcag gcggtagata ttttaaaggg taaaaaacca gcaagcattc
    49861 aggttgctaa gcctcaaaag gcaagcattg ctgttaatga tgatatggca agacttctgg
    49921 gcattgaccc cgaggtgatc aaggctcttg caagtaacgg agccaactag cgttttagga
    49981 ggaaggtatg aaaaaaggaa gctatttaat actgttagtg cttgcaggct tcgttttggt
    50041 ggcttgtcgt tcgacagcta gtcctcgtaa ggttaaccaa tctcatgtta acatcggtat
    50101 tttacaatac atggaacatg attcgctgac ggcagctcgt cgaggctttg aagcgcaatt
    50161 aaaggcagcg ggctatacta agggagacaa gctgagcctt cattatcaaa atgcacaggg
    50221 cgaccaagct aatttacaga cgatttcaga gcagctagtg aagcaaaatg atttgatctt
    50281 ggcgattgcg acaccggcag cgcaagcctt agcgaccgtc tcatcagata gaccaattgt
    50341 ttttacagca gtaacagatc ctatctcagc aggcttagtg gataggatca aaaagcctgg
    50401 tggcttgata acaggaacaa gtgaccaggc gccgattgca aagcaaattg acttgttagc
    50461 ccaagccttg ccagaggcca aaactattgg cattttatac acagctagtg aacgtaatgc
    50521 tgaggtgcag gtaaaggaag ctgaaacgct actgaccaag gttggttata gggttattaa
    50581 aaagggaatt gccacttcaa atgatgtgca agatactgct gcaagcttga tgagagcagt
    50641 agacgcgctt tttgtaccga cagataatac cgttgcttca accatgacaa tgctgggtga
    50701 gctgtcattg gctaataagg ttccaattat tggtggctca acggatatgg ttgatgcagg
    50761 tgggctcttg acctatggta tcgactacga gagccttggt agacaggctg gagaaatggc
    50821 cattaagatt ttaagaggac aggatccagc aagcctagca gtggagtacc caaaaacagt
    50881 caagctacat atcaatcaag caatggcaga caagctagcg attgatactt ccacattatc
    50941 agttgactaa attgctaggt taaaggctaa atgactgatc tctagccagc tggctaaatg
    51001 acaaagtctt aaccagttag cttagcttac tattaacgat tcatatgaca aaaaaggaga
    51061 aatcatgtca ctcattttat cgagcttatc acagggctta ttgtggtcta ttatggcaat
    51121 tggtgtttac ctgacatttc gtattttaga tattgccgat ttaactgcag aaggttccta
    51181 tccgcttggg gcagctattt gtgcaacggg tattgtatca ggtgtttctc ccttgctggc
    51241 tacgttttta gcttttattg gaggcttgct ggcaggcctt gtctcaggat tagttcacac
    51301 caaattaaaa ataccagcct tactaacagg aattatcact ctgacaggct tgtattctgt
    51361 gaatctaaag gtgctaggaa gagccaatgt ggctttatta cgtcaaagaa ctttagttac
    51421 ccagctctat gatctaggct ttaccaagct tgcagcggtg ctaattatgg gctttgtctt
    51481 tgtgaccatt gtgatttttt tattagccct gctgatgaaa actcagcttg gcctagctct
    51541 gcgatcgacc ggagacaata atccaatgag tgaagccaat ggtatcaaaa cagatcagat
    51601 gaaaatcatg gggtatatgc tatctaacgg tttgattgcc ctatgtggtg ccttgctttg
    51661 tcagaataat ggctatgcag atttaaatgc tggtgttggg acaattgtta ttgggctggc
    51721 ttcgattatc attgctgagg tgatgattag gcagctaagc attggctggc gcttagcttc
    51781 cattgtttta ggctctattg tttatcgctt aattattcta gctatcctag ccattcccgg
    51841 tatggatgca gatttggtta agcttttttc agccatgcta ttggcagctg ttctttttgt
    51901 gccagaatta cagcaaaggc ttcgccttcg aaaaacaagt ttaggatagg agaaatcatg
    51961 tcagcaatat tatcaattaa ggctattcac aaaacatttg aagcaggtac gattaacgaa
    52021 aatcatgtct tgagaggctt atctttggac attgaggagg gggattttat ctcggttatc
    52081 ggtgggaatg gcgctggaaa atccacatta atgaatactc tagcaggcac tctggctttt
    52141 gatcagggcg atattctttt agagggaaaa tcaatcaagc atttatcagc cgctaagcgt
    52201 gccaaggaca tcagtcgagt gtttcaagac cctaagatgg gaaccgcttc acgcttgacc
    52261 attgaggaaa atatggctat tgcttaccgc cgagggaaat caagggggct aggctggggc
    52321 gttaaagaaa gagagcgcca gatctatcgt caggccttgc aggaattagg cctaaatctg
    52381 gaaaaccgtc ttaaggccga gacacagttt ttatcaggag ggcaaagaca agccttgacc
    52441 ctgttaatgg cttccttagc aaagcctaag gtcttgttgc tagatgagca taccgcagct
    52501 cttgatccta agaccagtac aatggtaatg gctttgacaa agcagcttgt tgagacacat
    52561 ggcttgacaa ccctgatgat tacccataat ttggaaaatg ctattgctta tggtaatcgt
    52621 ctggtcatgc tccatcaagg taatattgtg gtggatatta agagagaaga gaaggccaag
    52681 ctgacggttg accacttgat ggcactcttt caccaaaata gtggtcatac gctccttgat
    52741 gatgcacttg ttttgggata ggctaggtga gggttagctc tgttttcaaa tagcagccat
    52801 aatgaaaagg cttaaagcca acgcttctag aaacgctagc tcaagccttg ttataatact
    52861 taggagattt ttctaagagt gataaagcca tgatgacgtc tattgtagtc aaaggatttg
    52921 tttcggatgc gataagcctc attttccaca atttcaattg ccttattcag ctgctgaatg
    52981 gtaatcgcct catcaatctc atgaaaagca gtgctataat aatcctcact aacacgttga
    53041 ttgcggtctt tataggtatt tttatgctct gttaaaatgg ccttagcctc agcacgtttt
    53101 gcaatggtat ctataatacc ttgaccatat gctctagcct cttgaaggat tgacagcata
    53161 ttgtctagag aatatgcgtt tgctaagcgg ctgacaaagc tatcagcgac ctcaggactt
    53221 aaattaatac catctaagtg ataaatcatc tctgggtgta gctttaggta atactgcaat
    53281 tcgcggaaca aaagcgctgg aattttcgac gaatccctat atggattgag ctgaatctcc
    53341 tgactatgta gcctattgat aaaatcgtcc ttgaactgct taatagcatc gtagtctgat
    53401 ttttctagct ctgctttaat attggctaga atctgggcgt ctgaataacg acgatagctt
    53461 gatagtgaag cagcaggcct actagtattg gaatttcgag aagcttctgc tcttctagtc
    53521 tctttgcttg gtgtttgctg cttatttgac tgagtctcct gctcggttag tcgtagctca
    53581 gggtgtaaac gactaatatt gttaagaaat tggttaacct catattctga tgaaaacttt
    53641 agcctaggtc tggccttgac cttctcaata gccttgtcaa taatcctttt cccgtacctt
    53701 ttgagattac tgtcagactg gatcaaataa agattaacat gtaagtgatc ttgactatcc
    53761 gccttagata agctgttacc aaggccaagg cttcctaaga gcgtagctag taacagcagg
    53821 tgttttacta gactacgctg aacaatattg tgacgactaa gcataagtta ttttcccatt
    53881 ctattgtaat ataccagaaa atgttatcaa aataaagata agatgtcaat gtcattaatg
    53941 gtggttaatc tttaattaat ggtcgttaat ctagtatatc agagagctag cttaggctgg
    54001 cagtggtcat tctgtgcgtc ttggtacgaa atgcccaagc agatgcagct cactagaatg
    54061 atcaatagcc tcaacacaaa gccccttaca gcttgacaca agctgtaagg ggctttgttg
    54121 tattaacaga taactcaaat ccttgctttt tataataaat ctaaggtttt tagcttgtca
    54181 tcaatcatgt gcagaacggt tgccaaatcc tctgggtttt gcacgaaatc aagcttgttt
    54241 ccatcaatct tcatcttagg tgaaacgtca tattgctcat accagcttgg gtattcacca
    54301 tgtacctgat ggtaataggc ttctaagtca ggattgtcgt caacctgctc aaaacgtctg
    54361 ccgcgctttt caatgcgctc tagcatcttc tcaaaggaga catcaatata aatcagcaga
    54421 tcaggccgtt tttaaggcat tccttcaagc tcctctagca tattggctaa gagctcttgg
    54481 taaatttcaa gctctgtctt ggtaacattt ccatttttat agttaagtgt caagaagagc
    54541 tcatcttcaa agattgagcg gtcaagaata ttattgtctg cctggtaggc ttctttaata
    54601 gatttgaagc gcttgttcaa aaagaaaatt tgtagtaaaa aggcatattt tttagggtct
    54661 tggtaataca gatcaagaac aggattgtta tcaacagcct cgtaaaatac ctctgttcct
    54721 aaatgctcac ccagtgcagc agcaagggaa ctcttgcctg cgccgattgt tccagctaat
    54781 acaatcaaca tgtttctcct tctatgtagt cttagtgtat ttgtgcaaaa atcgtttcaa
    54841 cctcagctaa ggttttagcg cgtgaaacgg cactgcgaat tttggcagcg cctgctgtcc
    54901 ctcgcaggta atgaggggct aacccacgaa attcacgaac agcaatagct tctcccttga
    54961 gcctgatgag gcgcttgaga tggtctttag caatatctag ctttttagca aagggcagct
    55021 ctggcaaaac ctctcctgtc tcaaagaagt gattaatttg ggtgaagaga taagggttgt
    55081 tcatagctgc acggccaatc atgaccgcat ctacaccaat ctcctcaatc atgaacctag
    55141 cgtcctgaac agttctgaca tctccatttc caataaatgg aatcctggta atagctcttg
    55201 agacgcgtgc aagggtttca tggtcacagg tgccagtata catctgctca cgagtacggc
    55261 catgcatggc aagagctgac acaccagcag cttcagcagc caaggcattc tcaacagcta
    55321 gtgagctgtc tgcccagccg gtacgcattt tgacagtcag tggaatgtct aaaacagagg
    55381 ttacctcctg aatgatatgg taaatcttat caggatcgcg aagccacttg gcacctgctt
    55441 catttttaac caccttgtta acaggacagc ccatattgat gtcaacaatg tcagccttgg
    55501 tatggctctg gataaaatca gccgcacgct ttagtccttc agcgtcaccg ccaaatagtt
    55561 ggattgacat ggggtgctca ttgtcatcaa tatgaagcat atgcagggtt ttttcgttat
    55621 tatagagaag tcccttttca gaaatcattt ccatgacaac aaggcctgca ccaaattcct
    55681 tggcaatcgt gcgaaaggcc gaattggtca caccagccat aggtgcaagc actgtacggt
    55741 gagggatttc cacatgacca atcctaaagg gtgagttaag ccttgtcatt gatcagcacc
    55801 tccaaatcag tttggtcaaa ttggtacttg gtgccacaaa attggcaaac aatttcagcc
    55861 cccttatcct cgtttagcat tgtcaacagg tcagctttag ggaggctcat tagggctgac
    55921 gcaaagcgct ctcttgagca gtcacactga aagctcagct gctcttcagc taatcgcttg
    55981 taaggctctt caccataaat agctgctaac agagcgtcta tatgattttc cgacgctaga
    56041 agggttgaaa tcgcaggcat ttcctgaatg cgcttctcat agtggctaat ctcttcgaca
    56101 gaagctccag gcagcacctg cagcataaag ccgccagcaa ccttgacctt gtcctcttga
    56161 tctagaagca cattaaggcc gacagcagat ggtgtctgct cagactctgt caagtagtag
    56221 gccagatcct caccaatctc accggtaatc aagggtgttg tagaggtgta gggattgcct
    56281 gttccatagt ccgtaattgt cacaaagtgt ccctgtccca taaaaggacc aaccagtact
    56341 tctccagttg ctgttttttt gatatcaaca ccgggatttt gaatatagcc cttgacatgc
    56401 ccttttgtgt cagcaacaga aataatatgc ccaaaggagg aatcgccaat aaccttgaca
    56461 gtaaccttac tatctccttt ttggttggca gctagaatct gattggcaat caaggtacga
    56521 ccaagtgcaa ccgttgaaga tgataaggta tgatgccttt cctgagcata tcgaacagtt
    56581 tcggtgcaat ccaaaacata ggccctgaag gcaccggagg cagaaattgt tttaattagt
    56641 ttatccataa tttctattat agcataatga acaaggcttg tgctggttgc tttagaggaa
    56701 agctgcttga aaatagagaa acactatttg gttaataata gcagctctat aaagccactt
    56761 aaaaacagag cagtgctaac aaatggtagt attcttgtcc ttagcacgca gtaagctaat
    56821 cacctaagtc agtacaatca aacaagcatc aaaaaacagc tccgataggt tgattaaagg
    56881 aagaaatgat aaaagagtta tttcgtaatg ctttgctgat aatgagcaag gtaatcatgt
    56941 ggtgtcgtat cagtgtactt tttgaaggtt ttcaaaaaat gggtggtatc gtagaaataa
    57001 aggagcttag ccacttctcc agctggtact cctcttcgta aaagtagctt ggcttcttgt
    57061 actttttcct tcaaaatata ggtctgcaac gaaatagaag aatacatttt aaaaacagct
    57121 cgtaaatgtg actctgagat ataaagatgc ttagcaatat ctgatacctt taattttgaa
    57181 taaaggtgct tatcgacgta atataaaata ctattataaa tttgctgctt atcagaaaca
    57241 cttttgttag tcaatgattc tgagaggcta ataatagcag ctgctcttat ttgaagcacc
    57301 ttaaggagat ctgtagcttt ttcagttagg ttcataaaat gcttaatgcg ctcgtagttt
    57361 ttggcaacat cagtattttc agtaaagctt agttcaagca gcttaataaa ataaataata
    57421 gaaagatttt tttcagctct taatgcggga atagaagagg agacgacatc tgatgaaggg
    57481 atacaattga tttcgtgctt taatagctct gtattaccca gcttgactaa atcaataata
    57541 tgattcaaat aatttaagac agctggcaca tgaaatgacg gggtattttc caattcgaga
    57601 ttagctataa tatgaggatc ctcccagatt agctgggctt cctccagtaa atcattaatg
    57661 ctttgctggc agctcatttc aaagttggtg tcaaaaaagg catcaacagc tatcaaaagg
    57721 cttcgaatat gagaagcagg aaaatgagga atggtagaga tatagccaac tagctctttt
    57781 tttgacttat caggatagcg cttcaagaag ctatcggcta attcctcctt atagctatcc
    57841 tgaaagaaag aggtgtaaaa aggcccaatg aaaataaact tgtcaccaat aggaaacatt
    57901 agagaggatt cctcaagcgt tccctcataa caagtgagct cagtattact aggaatatct
    57961 aatgttttaa ttaattcata gtaggggaat cgacgctcct cgtcatcata agcctgaagg
    58021 agctcaagat tttgagaaag cactaaaaca ggtaattgtg ataggttatg
//
LOCUS       DARYVE010000004        51453 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYVE010000004 DARYVE010000000
VERSION     DARYVE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51453
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            79..693
                     /locus_tag="TVW25_000198"
                     /pseudo
     CDS             79..693
                     /locus_tag="TVW25_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1223..2101
                     /gene="mvk"
                     /locus_tag="TVW25_000199"
     CDS             1223..2101
                     /gene="mvk"
                     /locus_tag="TVW25_000199"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1377876.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2083..3027
                     /gene="mvaD"
                     /locus_tag="TVW25_000200"
     CDS             2083..3027
                     /gene="mvaD"
                     /locus_tag="TVW25_000200"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1377877.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3020..4018
                     /locus_tag="TVW25_000201"
     CDS             3020..4018
                     /locus_tag="TVW25_000201"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1377878.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4021..5013
                     /locus_tag="TVW25_000202"
     CDS             4021..5013
                     /locus_tag="TVW25_000202"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1377879.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5298..6581)
                     /locus_tag="TVW25_000203"
     CDS             complement(5298..6581)
                     /locus_tag="TVW25_000203"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1377880.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6568..7743)
                     /locus_tag="TVW25_000204"
     CDS             complement(6568..7743)
                     /locus_tag="TVW25_000204"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1377881.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            7928..8767
                     /locus_tag="TVW25_000205"
     CDS             7928..8767
                     /locus_tag="TVW25_000205"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1377882.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            8848..9345
                     /locus_tag="TVW25_000206"
     CDS             8848..9345
                     /locus_tag="TVW25_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1377883.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9365..9535
                     /locus_tag="TVW25_000207"
     CDS             9365..9535
                     /locus_tag="TVW25_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377884.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9571..10800
                     /gene="clpX"
                     /locus_tag="TVW25_000208"
     CDS             9571..10800
                     /gene="clpX"
                     /locus_tag="TVW25_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1377885.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            10810..11409
                     /locus_tag="TVW25_000209"
     CDS             10810..11409
                     /locus_tag="TVW25_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1377886.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11773..14775
                     /locus_tag="TVW25_000210"
     CDS             11773..14775
                     /locus_tag="TVW25_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1377887.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(14965..17058)
                     /locus_tag="TVW25_000211"
     CDS             complement(14965..17058)
                     /locus_tag="TVW25_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1377888.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17429..17848
                     /gene="ndk"
                     /locus_tag="TVW25_000212"
     CDS             17429..17848
                     /gene="ndk"
                     /locus_tag="TVW25_000212"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1377889.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18349..19155
                     /locus_tag="TVW25_000213"
     CDS             18349..19155
                     /locus_tag="TVW25_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1377890.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19447..20412)
                     /locus_tag="TVW25_000214"
     CDS             complement(19447..20412)
                     /locus_tag="TVW25_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1377891.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20584..21867
                     /locus_tag="TVW25_000215"
     CDS             20584..21867
                     /locus_tag="TVW25_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1377892.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            21869..22729
                     /locus_tag="TVW25_000216"
     CDS             21869..22729
                     /locus_tag="TVW25_000216"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1377893.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            22894..24153
                     /locus_tag="TVW25_000217"
     CDS             22894..24153
                     /locus_tag="TVW25_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1377894.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24153..24776
                     /gene="folE"
                     /locus_tag="TVW25_000218"
     CDS             24153..24776
                     /gene="folE"
                     /locus_tag="TVW25_000218"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1377895.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24784..25584
                     /gene="folP"
                     /locus_tag="TVW25_000219"
     CDS             24784..25584
                     /gene="folP"
                     /locus_tag="TVW25_000219"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1377896.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25591..25950
                     /gene="folB"
                     /locus_tag="TVW25_000220"
     CDS             25591..25950
                     /gene="folB"
                     /locus_tag="TVW25_000220"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1377897.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            25947..26453
                     /gene="folK"
                     /locus_tag="TVW25_000221"
     CDS             25947..26453
                     /gene="folK"
                     /locus_tag="TVW25_000221"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1377898.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26549..27436
                     /gene="murB"
                     /locus_tag="TVW25_000222"
     CDS             26549..27436
                     /gene="murB"
                     /locus_tag="TVW25_000222"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1377899.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27482..28636
                     /locus_tag="TVW25_000223"
     CDS             27482..28636
                     /locus_tag="TVW25_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1377900.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28620..29414
                     /locus_tag="TVW25_000224"
     CDS             28620..29414
                     /locus_tag="TVW25_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1377901.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29411..30187
                     /locus_tag="TVW25_000225"
     CDS             29411..30187
                     /locus_tag="TVW25_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1377902.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30180..31253
                     /locus_tag="TVW25_000226"
     CDS             30180..31253
                     /locus_tag="TVW25_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1377903.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31411..32943
                     /locus_tag="TVW25_000227"
     CDS             31411..32943
                     /locus_tag="TVW25_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1377904.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33149..33763
                     /locus_tag="TVW25_000228"
     CDS             33149..33763
                     /locus_tag="TVW25_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1377905.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34111..35238
                     /locus_tag="TVW25_000229"
     CDS             34111..35238
                     /locus_tag="TVW25_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1377906.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35390..36067
                     /gene="radC"
                     /locus_tag="TVW25_000230"
     CDS             35390..36067
                     /gene="radC"
                     /locus_tag="TVW25_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1377907.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36069..36764)
                     /locus_tag="TVW25_000231"
     CDS             complement(36069..36764)
                     /locus_tag="TVW25_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1377908.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36776..37420)
                     /locus_tag="TVW25_000232"
     CDS             complement(36776..37420)
                     /locus_tag="TVW25_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1377909.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37706..38053)
                     /locus_tag="TVW25_000233"
     CDS             complement(37706..38053)
                     /locus_tag="TVW25_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1377910.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38043..39170)
                     /locus_tag="TVW25_000234"
     CDS             complement(38043..39170)
                     /locus_tag="TVW25_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1377911.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39173..40147)
                     /locus_tag="TVW25_000235"
     CDS             complement(39173..40147)
                     /locus_tag="TVW25_000235"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1377912.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40282..40854)
                     /locus_tag="TVW25_000236"
     CDS             complement(40282..40854)
                     /locus_tag="TVW25_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1377913.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            40949..41620
                     /locus_tag="TVW25_000237"
     CDS             40949..41620
                     /locus_tag="TVW25_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1377914.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41595..42431
                     /locus_tag="TVW25_000238"
     CDS             41595..42431
                     /locus_tag="TVW25_000238"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1377915.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42428..43330
                     /locus_tag="TVW25_000239"
     CDS             42428..43330
                     /locus_tag="TVW25_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1377916.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43334..44335
                     /gene="pta"
                     /locus_tag="TVW25_000240"
     CDS             43334..44335
                     /gene="pta"
                     /locus_tag="TVW25_000240"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1377917.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44435..45193
                     /locus_tag="TVW25_000241"
     CDS             44435..45193
                     /locus_tag="TVW25_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1377918.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45298..45984)
                     /locus_tag="TVW25_000242"
     CDS             complement(45298..45984)
                     /locus_tag="TVW25_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1377919.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46239..46967
                     /locus_tag="TVW25_000243"
                     /pseudo
     CDS             46239..46967
                     /locus_tag="TVW25_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            46960..48492
                     /locus_tag="TVW25_000244"
                     /pseudo
     CDS             46960..48492
                     /locus_tag="TVW25_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            48850..49833
                     /gene="guaC"
                     /locus_tag="TVW25_000245"
     CDS             48850..49833
                     /gene="guaC"
                     /locus_tag="TVW25_000245"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1377920.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            50019..50600
                     /locus_tag="TVW25_000246"
     CDS             50019..50600
                     /locus_tag="TVW25_000246"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1377921.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(50888..>51453)
                     /locus_tag="TVW25_000247"
     CDS             complement(50888..>51453)
                     /locus_tag="TVW25_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1377922.1"
                     /translation="DQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAALI
                     NLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQIK
                     DKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPEV
                     EGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14522 a         9753 c        11802 g        15376 t
ORIGIN      
        1 catcaagaac tggagaaata gagattatag agaaatagat aattcaggaa attctatatc
       61 aattgcttga cattgtaggg aaagtcctct atcatgaatt tgctgtatcg cttttatgat
      121 gtacaatcag gcctcattac agttgatggg caaaatattc aggagtattc tagagaaagc
      181 ctgcgttcac agatgggtat tgtcttgcag gatccttatt tgtttacagg aacgattgct
      241 tctaatatca cgatgggaaa tccagcttat tcggatcagg atattttaga tgctttggaa
      301 aaggtcggag cctcttcgat gattgctcgt ctggaaaagg gcattcatga gcctgtctat
      361 gaaaaaggct cctcttattc aagtggcgag cggcagctaa ttgcttttgc taggacattg
      421 attgccgacc ctaaaatttt gatcttagat gaagcgacct cgcacattga tactgagaca
      481 gaggacatca ttcaacaggc tatggaggtc ttaaagaaag gccgaacaac ctttatcatt
      541 gcccatcgct tgtctaccat tcaatctgct aatcaaattt tagtattgga taaggggagg
      601 atcgtcgaaa gaggaacaca tcaggaattg ctagatcagc aaggcattta tgctgaaatg
      661 tccaagctac aagaaaaggt ggctgtacag taatgctttt tagtgatagc tatcaaaaaa
      721 ttccttttct aggccgtgtt aagcagcagt agtctgtgaa gtaggagcta tatttaggtt
      781 ttgtgcctaa gcctttaagg tttttaagag gctggattag ggcttaacat caataaaatc
      841 atatgtcact ttatcacagc atgttgtggt gaagtgtttt ttgtgtcgtc ctgctaaagg
      901 gaagatcctc acagtcaggg cttggctggc tcctttatca gagtcagatc attcatacgt
      961 acttcctgtc aggcttggct aagttgaatt gtatgttgag atcagcatgt cagcaattta
     1021 tgctttgtgt ctgactttta gcagcttgta catgaaatag gactaaagga cacttgaatt
     1081 gatgaagaat cagcttaaaa accatttgtc ctagatagga taagaactgt ctaaaagggg
     1141 gatagatcat cgcaattttt aacaatttag tgtaaaatag taaggtgaat gttttgatga
     1201 aataaacgaa aagatttagg atatgaataa gacaattgga tatggcaagg cacacagcaa
     1261 aatcatttta atgggtgagc attctgtggt ctatggctac cctgcgttgg ccttgccctt
     1321 aaaagatatt gaagtgacct gccggatttt ccctgctgca aagcccttag cctttgattt
     1381 ttatgatccc ttatcaacgg cagtttatgc agccttggag catttggggt gcttggcaga
     1441 gcccattcat tatgatatta tgtctcaggt accacaaaag cggggcatgg gctcctcagc
     1501 agctgtttcg attgcagctg ttcgagctgt tttttcttat tttgggcagc ccttgtcaga
     1561 tgagctgttg gaaatcttgg tgaataaggc agaaatcatt gctcacacca atcccagtgg
     1621 cctagatgct aagacctgcc tcagtgataa ggccatcaaa tttattagaa atgttggttt
     1681 tgataccatt gatattcagt taaatgctta tttggtcatt gctgatacag ggattcaggg
     1741 gcatacgcgt gaggctgtca ataaggtggc tcaatttgag gaggaaaatc ttcctcattt
     1801 agccaagctt ggctgtttca cagaggctgt tgagcaagca attaagacaa acgattgcct
     1861 agctattgga cgattcatga cgcaggcaca tgaatcacta aaggctattg gtgtcagtgt
     1921 ggcaaaggct gatcagctgg ttgcagcagc tcttgaggct ggcgctttag gagctaaaat
     1981 gactggtggt ggcttaggag gatgtatgat tgcattagct gaaaggataa cagacgctca
     2041 gcaaatcagt aagaaactaa aagaagaggg agctgtaaat acgtggattc aaatactgta
     2101 acggtaactt cctacgctaa tattgctatt gtcaaatact gggggaaaaa agatgaggct
     2161 aagatgatcc catcaacctc tagtatttct ttgaccttgg aaggcatgta cacgacaaca
     2221 agtctttctt ttttgcctgc ctcagcaaag ggagatcagt tttatatcaa tggtgttctg
     2281 caggacgcca aggagcatgc taagattact gcgattttgg atcagttccg tcagaaggac
     2341 cagacttttg tcaaggttga agccagcaac agcatgccaa ctgcggcagg cttatcctca
     2401 agctctagtg gcttatctgc tctggtaaag gcctgcaatc agctttttca agctaagcta
     2461 agtcaagaag agcttgccca aaaggctaag tttgcctctg gctctgcttc gcgttctttt
     2521 tttggccctg ttgctgcctg ggataaggat acaggctcta tttataaggt caaaacagat
     2581 ttaaagctgg ccatgattat gctggtcttg aacgatgcta gaaagcccat ttcgagtcga
     2641 gaggggatga agcgctgcag cacaacctca acaagctttg accagtggct ggcccagtca
     2701 gaaagtgatt atcaggccat gttgcgtgcc cttagtgaca atgattttga aacggttggt
     2761 tggctgacag aagcaaatgc tctagccatg cacgcaacga ccaaaacagc cagtccttcc
     2821 ttctcttacc taacagaggc ctcctatcag gccatgctaa gggtcaaaga gcttcgtcaa
     2881 gagggctatt cttgctattt tacgatggac gctggtccaa atgtcaaggt gctttgttta
     2941 gaagaggact tagagcggct gtcgcacctt tttgaaaggg agtatcgtat catcgcctca
     3001 aaaacaaagg aattaccaga tgtctaaata tcatgttcaa gcaggaggaa agctgtatct
     3061 gacaggcgaa tatgcgattc taaggccggg gcaaacggcg ttgatttgct atattcccat
     3121 aatgctgaca gctgtcattg aagcagcaga ggctgttagt atcagctcag atatgtttga
     3181 ccatgctgct gatttgtcac cggataagga ttataggctg attcaagcct ctattgaagc
     3241 ctttagttta tatatagata aggatattaa ggagctgcca gccttttctt tgtctattac
     3301 tggtaagctt gagcgtgacg gtaaaaagtt tgggattggc tctagcggta gtgttgttgt
     3361 actaacgcta agagctttgg cagcctttta tcaggttcag ctgctaccag agcagctctt
     3421 taagctggct gcttataccc tgcttaaatc aggagataat ggctccatgg gggacattgc
     3481 ctgcattgcc tatgagagct tggttgctta tacatccttt gataggcgta aggttggtca
     3541 atggttgatc gagatgaccc taaaagagct aatggcagca cattgggggt atacgattga
     3601 gactattgag cctgctctgc cctgttggtt tcttgttggc tggacccaag tcccttctat
     3661 ctcaagagag atgattcagc tggttaacaa gagcattagc tgtcagtttt tagagcaaag
     3721 ccagctggtc acacaggaag tgatgactgc cctgcagctt ggtcaaagaa aaaggctcaa
     3781 agctagcatt gaaaaagcgg gtcagttgct gcaagggttg gcttcagtta tttatcaccc
     3841 taagcttacg cagcttgtcc aggcttgtca agggcttgat gctgctgcca aatcatcagg
     3901 ctcaggaggt ggggattgtg gtattgcact cgtttttgag gctaaggaca ttgagcctat
     3961 ccttgccaga tggcagcaag cagggattgt attactatat caggaggaat ggggataaac
     4021 atgactaatc gtaaggatga ccatatcaca catgctttga gctatcattc tccttacaat
     4081 gcatttgacg acatggagct cattcactgt tccttgccga gctatgattt agctgatatt
     4141 gatctctcaa cccattttgc tggctgtgat tttgagtttc ctttttatat caatgcgatg
     4201 acaggtggta gcaagaaagg ccaagcagtc aatgaaaagc tggccaaagt ggctgcggct
     4261 acaggtattt taatggtgac aggctcttac agtgcagcct tgaaaaatcc tgaggacact
     4321 tcctttcaat tgcgaggtgt agcaccagat ttacagttgg ccaccaacat tggtcttgat
     4381 aaggctgttg acctagggat tagagctgtc gaggaaatga agcccttgtt tttacaggta
     4441 catgtgaatg ccatgcagga gctgttaatg ccagagggag agcgcagctt taagcattgg
     4501 aaggatcatt tagcggccta tgccaagcag cttccagtcc ctttgatttt aaaagaggtt
     4561 ggctttggta tggatattaa gaccatcact atagcacgtg atatgggagt aaaaaccttt
     4621 gatatttcag gaagaggagg aacctccttt gcctacatcg aaaatcaaag aggaagtaat
     4681 cgctcttacc tagacgattg gggacagaca acagtgcaat gtctattaaa cgccaaaggt
     4741 ctggttgatg aagtggagat cttagcctca ggtggtgtca gacacccctt agatatggtt
     4801 aaatgcttgg tgctgggggc acgtgctgtg ggcctatcgc gagtggtatt ggagttagtt
     4861 gagacctatc cagttgagca gatcatcgct acgatcaata gctggaagaa ggagcttaag
     4921 ctcatcatgt gtgctttaga ttgtcgaacc ttgagcgatt tgcgtcaggt ggattattta
     4981 ttatatggta ggctttatca ggcaaaccgc taaagacttt ttagccctga gctaactttc
     5041 cttagaaaat catcacagga gttaagaagc tgcctgcttg gtgctgcaag ctaattcagc
     5101 tgattatggc tcgtaagatt tttagatgtc tgaatgaaat gataggacag atgacatagt
     5161 atagcgctaa tttctagtga aaatcagtcc ttggtcaggt tactgagact gaggttaagt
     5221 ttatgtttac actaacactt aaaggatatg aaaacacttg gtagctgcca ctgaagctgt
     5281 taccaagtgt ttttagtcta tgattggctt aatcgtatgg ctgttaagag ctgtcctgcc
     5341 ttttctaggt tcattggctt atcctttagt agagccttaa ctagttgagg cacctcctgc
     5401 tcactagcac ctgctaatag agctagagac ttggcctgca gcttcatgtg accagcctgg
     5461 ataccagttg aggtcaaagc ctttagagcc gcaaaatttt gcgccagccc aactgcagtg
     5521 gtgatttggg cgagaacctt agcatttggt tgctctaaaa ggctatgagc aacactgacg
     5581 gttgggttga gaccgatcga ccctccttta ctagcaatgg gcattggcag tgttagctct
     5641 ccgcataagc tatttttaga taaatcaacg tgccagctac ttagccctct ataagagcca
     5701 gtccttgcgg cataggcatg tgctccagcc tcaatagctc tccagtcatt tccggtagct
     5761 atagctaccg catcgattcc attaaagatt cccttattat gcgttgctgc tcggtaaggg
     5821 tcaatctggg ctaatttgct tgccagctct atttttttgg ccaattgctg agcttcttcc
     5881 ttatgtcgac ttaggtatct gaggtcaacc tgacatttag cactaactaa agcttttgtt
     5941 gcatagtttg agaggatagc cattaagcat tgaccaccgc ttagggcctc caaatcaggt
     6001 actaaagcct ccatcatcgt gttaacgatg ttggctccca tagcctcttg ggtatcaacg
     6061 ctcagataga caatgaaaaa atcctcctta cgctcaacgg taaggctctt tgcgccacca
     6121 ccacgcttaa caatagaagg gtaggcattg tttgcaacgt caatcaatgt atctgcgtta
     6181 gctagaatag ccagcctagc ctgctcgtca tctttaacat cataaagagc tacctgccca
     6241 agcatttgac gactgagtac ctcagtctga aagccacctg atcgcttgat gattttggca
     6301 gcaaaggaag cagcagcaac aacagaaggc tcttcagtca caaaggggac ctgataggta
     6361 tgcccattga tcagaaaatc aggggctaga ctaaaaggca gagccagtcg accgatgaca
     6421 ttttcggtca tttgattggc aatagcaatg ggtaagagct ggtctgtctc taacagcttt
     6481 tgctgctgcg ggccaagcag ctggtcatct gcgagctgtt gaatgcgttc tgcaaggctt
     6541 tttttataaa agccggccca atttggttta gtttttgtca tcatcttgat aaattcgttg
     6601 gtgttcctta atttctttga gggcaaacct gccagttaga tatggtgaaa agctggcatt
     6661 gccatcttgg tctagtctag gctcttcata aaaaagtgct tcataatcag ccactgaaat
     6721 cacctgacgt tggtctaata gggcttgtcg attagtcagt agcatgtcct tgtaaccgtc
     6781 aacaagctgc cctgaaaaca gctcactaac agctcctgag ccatagctaa acaatccaat
     6841 cctatcacca gcccttagca cctgactatt ctctaaaagt gataataagc cgaggtagag
     6901 tgagcctgtg taaatgttgc cgatttgctt gctgtaggca atagaagctt gaaagttttc
     6961 ataaagcctt tctttgtgat catctgctag tgattttgtc atgatcttat gaagtccctt
     7021 tagagcaagc tttggaaagg ggatatgaaa acaaacagca gcaaggtctg atagctcaat
     7081 accttctttt tcttggtatt tgtcccaggt tgtttttagg gaatcaaggt attgcttggt
     7141 cgaataaata ccattgacaa atggtgttga gctgtaattt ggacgccaaa aatccatcac
     7201 atcacgtgtc tgtgcgacat tgtcatgatt taactggaga atacgaggat tagtagtaac
     7261 tagcatagca atacttccag caccttgtgt tggctctccg gcggatccaa tgccgtattt
     7321 ggcgatgtca ctggcaatga ccaagacctt ggaggctggg tgtgcagcaa catgtaattt
     7381 ggcataatct aaagcagcag tagcgctgta gcaggcttcc tttatctcaa aggagcgtgc
     7441 aaagggctga atatcaagca gctgatgaac gtaaatactg gctgcctttg attgatcaat
     7501 gcttgattcg gttgctaaaa tgaccatgtc aatgcttgct ttatcgtctt tggtaaggat
     7561 ttggtcagca gctgatgcag caagcgttac aatatcctct gtaacaggtg caatgcttag
     7621 agcgtcaagc attagcccct gatgaaattt tgctggatca gtgctgcgag caagtgccag
     7681 gtcttccatt tttaagacgt attgactggt cgcaaagcca atcttatcaa ttccgatgtt
     7741 cataaatatc cttcttttat ccattttata gtcctatcca ttttatcata ttttcttaga
     7801 aaattagctg atttaatacg atagttttac ctttcaaacc aaaaacagca gcatatagct
     7861 ttcttctggt atttttgaag gaaattagat aaaataatat ggactgtgct tacagaaagg
     7921 ggtttccatg acaaaagcag atcatatttt taaagctaat atcaaaaaaa ttatggagga
     7981 gggagtcttt agcgagcagg ctcgcccaag gtacaaaaat ggtcaaacag ccaattccaa
     8041 atacattaca ggtgcttttg cagagtatga tttgtctaag ggagagtttc ctattacaac
     8101 tctaagatca atccctatca agtcagctat taaagagtta ttttggattt atcaggacca
     8161 atcaaacagc cttgatgttt tagaaaacaa atacaacgtt cactattgga atgagtggga
     8221 ggtcggtcag acaagaacca tcggtcagcg ctacggtgca atcgttaaaa agcatgatat
     8281 catctcaaaa atcctcaagc agctagagga caacccttgg aatcgccgaa atgtgatttc
     8341 tctgtgggat tacgaagcct ttgaagaatc agaaggactg ctaccatgtg cctttcaggt
     8401 gatgtttgat gttaggcgag tagatggtga gctgtattta gatgccacgc tgacccagcg
     8461 ctcaaatgat atgctagtgg ctcatcatat caatgccatg caatatgttg ccctgcagct
     8521 aatgattgcc aagcattttg gctggaaggc tggtaagttc ttttattttg tcaataattt
     8581 gcacatctat gacaaccaat ttgcgcaagc caaggagcta ttggagcgtc agccagcagc
     8641 ctgtcagccc aagcttttgc tgcatgttcc tgatgggaca gacttttttg atataagacc
     8701 agaggatttt gagctacagg attattaccc agtgaagcct cagctcacct ttgacttggc
     8761 gatttaagcg aaaaagacga ttttttctga gcattttgcc aagaaatttg atagaataaa
     8821 agaagttcat attgaggaaa gctagtgatg acaaagaaga ttattgctat ttgggcagag
     8881 gatgaagcag gacttatcgg agcgtgtggc aggcttcctt ggtacctacc aaaagagttg
     8941 cagcatttca aggaaacaac attgaatcaa gctatcctga tgggacgagt aacctttgag
     9001 ggcatgaagg gtcgtttgct gccaaatcgc caaacgcttg ttatgaccag agacagttat
     9061 tatcatgtgg agggcgcttt aaccataacc agtgtgcagg aggctttgga ttggtatcat
     9121 gcgcaggata agaccttata tgtgattggt ggcagcaagg ttttagaggc ctttgatggt
     9181 tattttgatg tcatcatcaa aacagtggta catcaccagt ttgagggtga tacctaccga
     9241 cctaggttag agctgagtga ttttgtagag gagacctctg tattgtaccc aagggacgat
     9301 aacaatcctt acgatttcac tgttacagta ttgagacatc gctaatatag ggagatgata
     9361 gtctatgcag cgtagtattt ttggggtatt tacggccttt ttgtgtgcga tttgtgtttt
     9421 atgtgccata ccggccttta gaaaaaatcg ctatggctta ggattacttt ttttattaaa
     9481 tgcctttact aacctagtga ataccataca tgccttttat ggaacactgt tttaagccta
     9541 agagaatgaa aagagaaaga tagaggaatc atggcaggaa atcgtagtaa cgatattaag
     9601 gttcattgct cgttttgcgg caagagccaa gacgaagtga aaaaaattat tgcaggtaat
     9661 aacgtcttta tttgtaacga atgtgttgcc ttatcacaag aaatcatcaa ggaagaattg
     9721 gcagaagagg ttctcgctga tctgactgag gtaccaaagc caaaagagct gcttgagatt
     9781 ttaaatcaat acgtcattgg gcaggagcgt gctaagagag ccttatcagt tgcagtttac
     9841 aaccactaca agaggatttc atttactgag agtcgtgatg atgatgatgt ggatttgcag
     9901 aagtccaata ttctgatgat tggaccaaca ggctcaggaa agaccttttt ggcacagacc
     9961 ctggctaaga gtctgaatgt tccgtttgct attgctgatg caacctcttt gactgaggca
    10021 ggctatgtcg gagaagatgt ggaaaatatc ctcctgaaat taattcaagc cgctgattac
    10081 aatgttgagc gtgcagagcg cggcattatt tatgttgacg aaattgataa aatcgctaaa
    10141 aaaggtgaga atgtctctat cactcgtgac gtatcaggag aaggtgtcca acaagccttg
    10201 ctaaaaatca ttgaaggaac ggttgctagt gttccaccgc aaggtggtcg taagcaccca
    10261 aaccaagaga tggtacagat tgataccaaa aatatcttgt ttatcgtcgg aggcgccttt
    10321 gatggtatcg aagaaattgt caagcagcgc ttgggagaaa agatcattgg ctttgggcaa
    10381 aatagtcgaa agattgatga caatgcttcc tatatgcagg agatcattgc tgaggatatt
    10441 caaaaatttg gtctgattcc cgaatttatt ggacgcttgc ctgttgtggc agcgcttgag
    10501 cagcttaata ctgaggattt gattcgtatt ttaacagagc ctagaaatgc ccttgtgaag
    10561 caatatcaag ccttattgtc atatgatggc gtagagcttg agtttgaaaa gggggctctg
    10621 gaggctattg caggtagggc tattgagcgc aagactggtg cgcgtggtct gaggtctatt
    10681 attgaagaaa ccatgctgga tatcatgttt gaggtgccaa gccaagagga agtaatcaag
    10741 gtacgcatta ctaaggaagc tgtcgaaggt caatcaaagc ctattttaga gatagcctaa
    10801 ggaggtatga tgtctgaaga gcaaatcctt aacacgcata atgcttcgat attgcttagt
    10861 gcggcaaata agtctcatta cccacaagac gaccttcctg agattgcttt ggcaggtcgg
    10921 tcaaatgttg gaaaatcaag ctttatcaat actatactag gacgtaaaag ccttgctaga
    10981 acctcaagca aacctggtaa aactcagctt cttaattttt ttaacgttga tgataagcta
    11041 aggcttgttg acgttcctgg ctatggttat gctaaggtat ctaaggcaga gcgggctaga
    11101 tggggaaaga tgatcgaaga gtacctgacc acacgacaaa atctcagagc agttgttagt
    11161 ctggttgatt ttcgccatga gtcatcacag gacgacattc agatgtatga gtttttgaag
    11221 tattatgaga ttccggtgat tattgtggct acaaaggcag acaaggttcc tcgtggtcgc
    11281 tggaataagc atgagtctat ggttaaaaag tccttaaact ttgatcaaac agatgcgttt
    11341 attatttttt catctgttga gcgtatcggt attgatgagt cttgggatac cattttagag
    11401 tatttataag catatggtaa aaaatttaag tatcttttag acaggcactt gtgtctggtc
    11461 tgagaggtgc ttttttattg acaaaaaaac aatttgttga tgacgagctt gtgttcaaaa
    11521 atgtcagttt gctaaaaaat gatgataaca aacaagactt ttatgatata atgcttagca
    11581 ggataatatg gagacatgag aaaaaggtca gagacagcta atttgctatc cctgattata
    11641 actatgatga ccagcattat tataatactc atggtgctag ctattagtag cagcacctaa
    11701 cctatagtgt tgctttttag gttacaagca ctggcgctag gagtattata atatatttag
    11761 aaaggttttt ttatgacaat aaaaaaatgc cctcaaatac ttgccttatt ccttgctttt
    11821 gcagcgctag ctagtcaggg gcaaaccgtc catgctctgg agcggcagga gacatctgtc
    11881 aagcaagctc atgaatcaga tgattggttt gatgaggacg aaggagttag cgatatcaag
    11941 tctaataccc ctacagagat agactcaaca gtaacagagt tatttggtga tgctgagcct
    12001 aagactaagg ctgaaaaaga agagtcaaaa gctccaagcc ctaagcaaga agcactgcca
    12061 gcagagtctc aaaaagaaaa agagacatct gctaaatcga ctgaccatgc gacagtacaa
    12121 gcagaagagg cacagcctga gcaaggctca gatagtcctt ggctagcaga tgactttgtt
    12181 actaagggag ataccttggt tgggctatct aaggcaggtc ttgctaagtt atcaaagaca
    12241 cctgtcttgg tactaccaag gatagggatt gacaagacag tgttgacaag gattgctagc
    12301 tttgccttta ctccaaataa atcagtcgct attgctgatt atacaggtag agcaggtgaa
    12361 catggcgaga tcaatcatct ggacgtcgaa ggcagagata tccttactga gggagaggat
    12421 tttggtgcct atgcgattaa aaagcttgtg attcctgaag gctatctttt tatcggtcaa
    12481 gatgccttta atgacaataa acagctagaa gaaatcagtc tacctgatag cttactcagt
    12541 atttcagact atgcctttgc tcacatgagt ttatctaagc ttaagctgcc aaaaagccta
    12601 cagtccattg gagatcaagc cttttttgat aatcggattg caggcacttt ggtattgcca
    12661 aaagctctaa agcagctggg agaacgcgtc tttaagtcca atcgcctcac tggacttgtc
    12721 tttgagggag aaggcttgtc tgtcctaaaa gaagcagcct ttcaagacaa tgctttcatt
    12781 agtcttgtta tcccagatag cattcaagcc ttagaagagg acgtctttac aggaaacctt
    12841 ggcgatgaag aatacggtaa tcatgccgtt ttacgaacca aaaatggtca gaatccttac
    12901 agacttcaca gtgccaatgt tcttgtcaat ccaagtgatc aggctagaac accacagcca
    12961 ccaattgatt acaacaggtg gcttgcagaa gattttacct atactggaca gacgataacc
    13021 ggtttttcag ctagtggact gcgcaaggtc aaacgcaata agcatttggt tctgcctaag
    13081 aattatcagg gtcagccctt gacagccatt gcagataatg cctttagaaa tgtcaatttt
    13141 catgataaaa ccttgcgtaa atacgaccta gaaagcgtga cgttaccatc taccattcaa
    13201 aagattggtg cctttgcctt tcagtcaaat aatctagaaa gctttgaggc cagcgaggac
    13261 ttggttgaga ttggtcaagg agcctttatg aataatcgca ttgagattct ggccttgaat
    13321 gataagctga aggtcattgg agatgcggcc tttcatatca atcggattta tgctattgtt
    13381 atccctgagt cggtcgaagt aattggcatt tctgccttta ggcaaaatgg tgctaaacat
    13441 gtgatgttta tgggagataa gctaataagt attggagaaa tggctttttt gagcaatact
    13501 ctggaggaag tggatttgag cagcttagca gggcttaaga ccatcgctgt tcaagccttt
    13561 gcagacaatc acttgagaga gcttaagctg ccagatagtt tgatgcgtat tgaagcagaa
    13621 gcttttaaaa ttaatagact tcaaagagtg accgttccag acactgtcat tagcattagc
    13681 tttaatgcct ttgatcataa tagtgatgac aaggttgtcc taaggaccac caatcacaat
    13741 aaaaacctgc tagctgatgg aaatggcttt attgtggatc cagacctatt aagtgcggat
    13801 caatcgactg ttcaagcagt tttagaggac ctgcggcgct tagatctagc tagtctacgt
    13861 gctgatacag cagctcattt tatgacactc atcacaagag gtaagcagct actaaaagaa
    13921 tccgctgtac ggttaggtta tcagcttagg ttccttgcag agtcacgatt tttcttaggg
    13981 cgcgtgagac tggatcagct gattaaaact gctgacataa ccctatctag ccatcaagac
    14041 acacctaatg ctaagctgtt gatggctaag ctagacaagg ccaagctgca ttacaataat
    14101 agcgcaatga ctgctccaaa agtaagtcgc ttggaaaaag agctcagcct gttaattgat
    14161 cttgtccaag gggtaggcgc tatctctaaa gcaacaatga ctcaaggtgt ctataagctt
    14221 cagacaaccc tacctattcc agagtattat attggggtta atctttatac tgatgatcag
    14281 gggaatattt tatttgtgct tgacatgagt gatacgattg ggcagggaca acttgatgac
    14341 tatggcaatc ctattttaaa tgttgatgag gataatgaag gctaccatgc tttggccatt
    14401 gagtccttag cagattacga aggccttacg attaaggata tattgaccaa ggagctaaat
    14461 caattgccta ttcgcgatgt caagcaagca agagagcatc gtgttggtct ttttatggca
    14521 atcagagatg ctgcaaggga agctcagctt ctactagaaa agcagagcaa agccttatca
    14581 gaatcagccg gcaaatctaa tggctcaaaa gtagctgact caggacttga gccttctgtg
    14641 acactatcaa ccaataagac taagctgcta ccaaaaacag gagccttcaa agaagcttgg
    14701 gtgacaatga tcggaatgct tgttcttttg gcggctaccc tacttaaagg cgatagtcgc
    14761 tacaaaaaga agtaaatagg cttgcttagc aagcacactc tagcaccagt aaggcttgag
    14821 gggcttacaa agcctatcta atctagcaat agtatattgc cagtgtgagc tggtgcttga
    14881 gcttcaaaaa aacaaaagag cctgaaatga cttttactag catttcaggc tctttttagc
    14941 ttgtgattct tttttgtgtg aagcttactt ctcacttatc gtaatagtat cttgatcaag
    15001 gcttgctaat aggtgtttag cagtcgggtg atccaggtag taatccgtaa tgcggtcacg
    15061 aatttcttgt tcgatgacac gtctaagtgg acgaactccc atcgcatgat catagcccag
    15121 atcaatcaaa cgctctttaa catcgtcagt cacctcaagg ctaatgcctt ttttagcaag
    15181 ggtttggttc acttctgtta gcattaaagc aacaatttct tgtaaatcct ttttcgctaa
    15241 atggttgaat tcgatgacac cgttgaagcg attcaagaat tctggtctaa agtaaggtgc
    15301 aatacgctcc atgatagcag gctcttgatc agcacgatct cctgcttgat ggccaaaacc
    15361 agcattagag gttgcgatga taaccgtatt tttgaaattg atcgtgttgc cttgtccatc
    15421 tgtcaatcgc ccatcatcaa gcacttgaag aagcagtgta atgacctgtg ggtctgcttt
    15481 ttcgatttca tcaagcaaga tgatagagta aggactgcga cggacacgtt ctgtaagggt
    15541 attttgatta tcatcatagc caacatagcc agctgttgtt ccgattaatt tggaaacagc
    15601 tgtgcggtca ctatattcag acatatctaa gcgaatgata gcgtcctttg agccgaacat
    15661 atcaagggct aactgcttag ccagctcggt cttaccaaca ccagttggac caacaaagag
    15721 gaaggagcca attgggcgat taccgtcatc aaagcctgcg cggttgcgtc gaatcgcacg
    15781 agcaacagcc tcaactgcac catcttgtcc gataacatgg cctttaagac ggttactgat
    15841 ttccttgagc ctttctaaat cactagcccc catatttgat actggaacac cagttagacg
    15901 ttcaacagat tctgcaatat cattaacagt ggcagtgacc ttttgccctt cactgtgatg
    15961 attgatttgc ttttggagct cctcaatgcg ggtcttagca gttaaggcct tttcaaagtc
    16021 ttcttctgca acagcctttt cctgtagctc cttttgctta gtgatttctg cttcaagtga
    16081 ttttagatca gtgacagggt gctgagctgc tagatgagca gcagtcatat caacaaggtc
    16141 aatggcttta tctggtaggc ttcgttgtgg aatatattgg atagcataat caatagctgc
    16201 cttcaagaca gagtctggta ggatcacatt gtggtgctgc tcgtagaggt tgcgaatgcc
    16261 cattaaaatg tggaaggtat cctctgctga aggagcatta accttaacct cgttgaaacg
    16321 acgagcaaga gcagcatttt ttagaatggt gttgcgatac tcatcttgag ttgtggcacc
    16381 aatcagggtc aactcaccgc gtgagagggc tggttttaga atatcagcta agcccttaga
    16441 gcctgagtct gaaccagctg accctgcacc aaggatttga tggatttcgt caaagaagag
    16501 aatgatattg ccagcctcct taacctcttt aaccatgttt tgaatgtttt cttcaaagga
    16561 gccacgatac tgtgtgccag cctcaaggcc agaaatatca attgagataa tctctttatt
    16621 tttgatggca gctggcacat caccgttgac aatagcctgg gctaggcctt cgacaacagc
    16681 agttttacca acaccagcgt caccgacaag aacagggtta ttcttggttc gtcttgctag
    16741 aatttctgcg gtcgcttgaa tctcatcgtt tcgtccgatc acaggatcta acctgccttg
    16801 ccgagcttct tcggtcaggt ttgttccgag cttggttaga atgccgtctt ttttaaggct
    16861 gctagcctgt ttttcttgtc cctcagctgc agctagctta ccggttttcc ggtattcttg
    16921 aaattcctct ggtgtcatct cacgtccatt gacaagatag cgacgatttt cgctgcggta
    16981 gccgccgatg tttcccatta actgattgaa aatatcgtcc atattttcaa aggggtcttt
    17041 tccataatag gttgccatat acacttacct cacttgtatt atatttacca gtcattatga
    17101 gctactggta taggtagaag gtgatcggtg ttggctcata cagagatcat agagaggtct
    17161 tatgagagtc tattgctcag gcttattact caccttctaa taatattata tccaaaaggt
    17221 cagtaaaggt caaacaaaaa gtatgaataa ttaaccttta taatcaggtg cttatagccc
    17281 ttgaaacatc agatgactat gccataagct gctggtgctt ttttgctagc aaggctatct
    17341 gtaaagaaga gacttttgtc aaaaatggtt ttactttttg ttctaaaggc tttcatgata
    17401 taataaaaga aaagcacaga ggtcaattat ggaacaaaca ttttttatgg tgaagcctga
    17461 tggtgtgaaa cgtggcttgg ttggagagat tctacgccgg attgagcgtc gtggctttac
    17521 ctttgatagg cttgaattgc gacaagcaac cccagaattg ctagctaagc attatgacac
    17581 cttaatcaat aagccctttt atccagagct agaggcctat atgacaagcg gacctgtttt
    17641 aatcggcatt atctccggta atcgtgtggt ctcttcctgg cgaaccatga tgggggtaac
    17701 caatcctaaa gacgctttac cggggactat tcgtggtgat tttgctcaag cccctggtga
    17761 tgatggcggc attttcaacg tggtgcatgg ttcggattcg agagattcag ccaagcgaga
    17821 aattgcgatc tggtttggac atagctgaca ttgggcttgg gcctattctt ttaagaactg
    17881 ataaagcaat tgcataaggg gttgataagc ccatcatcaa tagtagctca gcattagaag
    17941 ggtaacagcc ttgatgttgg gctatttttt tgcttgccta gggtctgtat gcttgtcctg
    18001 atgagcaggt agacaaagca gcataagttt aacaatcctt tgcggcagtg atcaattgta
    18061 gctctaacca tagcatcagc tatttgaaag ccttgaaaaa gaaagctaag gctaacaagc
    18121 tagtctaggt catttactac aagcgacttt tttcaattag ctgctcaagg caagtattga
    18181 aaaaagtcca tttttcatgt catttgtaat aatatggtat atttttaacg aaaagtcgtt
    18241 ttagttgaga aaatatacaa aaaaggctat gatatagtta ataaagttgt tataccccct
    18301 gtgtcttgta cactatgact tgtagagagt ttatcaaagg aggataagat gaacaaacaa
    18361 agcatgaccc atttttctaa gaagctgatg aagttagccc ttttaggttt ggcattgcca
    18421 ttaagcttgg tgtcggtggt agatactccg gttcttaacc aatccgaaaa agctgtttat
    18481 gccaatgatt ttggatctgg aaatcgagcc agtgattatg taccggcggc taacgcttgg
    18541 agctttgagg cttatccaga ttactacagt attttaggag ctagtcatct taatcctgct
    18601 gtctttccag agcctagtaa gatgtcatac agtcctttag acgagttggg ccgcacacag
    18661 gtcgcaagag gaacaataac ctatcacaat atcgtgatga attacaatgt tcggcaacgc
    18721 tttgctaaaa atcagaaccc ttcaggctgg attggtaacc ctagaaatgt tcgctacact
    18781 attgagtggc tagatggact atcctatcag ggagattttt ggaatcggag tcatttgatt
    18841 gcagatagcc ttggtggagc agccttacgt gtcaatgcta ttactggtac aagaacacaa
    18901 aatgttggcg gcagaaatca aagaggcggt atgcgctata ttgagcaaaa ggtgcagcag
    18961 tggattgagc agcatacaag cgcagttgtt tattacgaag cggtgccaat ttaccaggca
    19021 aatgagctag ttccaagagc tgttgttgtt tcagcattgt catcagacgg aggtcttgac
    19081 gaaaaggtca tggtctataa taccgccaac ggctatacca ttgattatgc cactggcgca
    19141 ttccgcagta actaggcttt tgtactaagc tgtagctgat caaggtctga ctaagacaag
    19201 ctcatcagca attggtatat aaaaagacgt ggcaacaaca tgttttaaat gagttgtcat
    19261 gtctttttag tgtcgtcagc ttttcacatt gtcttagaat gatcacacct agctagccgc
    19321 taaaagcatt ggtccaaaga aatgttaaga atagatagaa tgccttttaa tcagtggtat
    19381 gggactgcta gctaatataa tgcctgcagt tgagccaatt tctcatctag gctaataact
    19441 aacaagctat tgacttatcg tgttcattag aatgtcagct gttgtagttg gtagtattcg
    19501 aatacgatta agcgatagca ggccattagc agcacttgct agtccttcat ttgttgtgac
    19561 ccctaatttg taatgcagat cctcagcaat ctttaatgtg gtatcagtat aacgacctgc
    19621 tggataggca attgcaatgg tatcttggtg tagctctcta tctaggtatt ctttagaatc
    19681 tttcatttca gcggtttgac tagcagcgct tgcctgagat agatcagggt ggttaaccgt
    19741 atgatcttgg aaagacatgc ctgcctgctt catttccttc atctgatcca atgtaagatt
    19801 ggccgcatta cctgcctctg taaagccagt gataacgtta ttggtggcct tgatgtcata
    19861 ctttttcagg attggaaaag caacgttgta aaaatcaacc atgctatcat caaaggttag
    19921 ccagacaacc ttttcagcag gaagctcgtt agctgataag actcggtagg cttcttcggg
    19981 agataaaaag tagtagccgg cctccttcat tgcctttagc tggctttcaa aaagatctgg
    20041 agcaacgatg agattggcac ttgctgcctc ttctggtgcc ataacgtgaa tagcatgata
    20101 cattaagata ggaagcttaa cagggttttg ctgcttggtc cagctgacag ctcctttttg
    20161 ctgctgacta tttgtatggc tagcttcctt attagttgct tttttgctag gcttgggagc
    20221 tggtttttta tcagtttttg aaaataggct tattttgggg attgcctgcg ataattgaga
    20281 gatgcttatc tttgaatggc tcttgtaaag gtagacaata gctgataagc ctatgataca
    20341 ggcaagtagt agcatgagat taatcatttt gaagattttt cttttcttac gccgtttgtt
    20401 tctgttgttc atcacttgct ccttgtttat tgattagtct attgtaacat ttttttaagt
    20461 aagctgtctt tcgttaactt aattttttgc taacattcta ttagtgttat gctttgtaaa
    20521 acaagaccta gatttgctat aataagacag agtatttaag acagtcaaaa aaaggaggat
    20581 aggatgtcag ttaaggttgc attattaggc tttgggactg ttgctagtgg cattcccttg
    20641 ctattagaaa acaatagtag caagattcgt gcagtggtag gtgatgattt ggtgattgca
    20701 aaggttctgg ttagagatga gaccactaag aagcgtttgt tggatcaagg ctattcctac
    20761 caatttgtga cctccattga tgatattgtt gatgatgaga gcattgatat ggtggtcgaa
    20821 ttaatgggtc gtatcgagcc tgcaaagacc tttatctcgc gtgctctatc agccggaaag
    20881 cctgttgtga ctgctaataa ggatttgata gccttgtacg gaggagagct ctcgactttg
    20941 gcagctaagc atcaggtagc tttgtactac gaggctgctg ttgctggtgg tattccaata
    21001 ctaagagctt tggctgattc ctttgcctca gataagctga cgcgtctgct cggtgtgctc
    21061 aatggaacaa ctaatttcat gttaaccaag atgattgatg agggctggac ctatgaaagg
    21121 gccctgcaaa aagcgcagga gctgggctat gctgaaagtg atccgactaa tgatgtgaaa
    21181 gggatcgatg cagcttacaa ggttgctatt cttagtcagt ttgcttttgg aatgaccatt
    21241 gactttgagg ctattagcta ttcagggatt gataaggttc gagtagaaga tgtgacagta
    21301 gcgcagaagc tgggctatgt gatcaaatta gttggtctac ttgaagagac ggcttctggg
    21361 cttaacgcag aggtatcccc agtcttttta ccaaagacac acccgttggc tgctgtagac
    21421 ggtgtgatga atgctgttta tatcgagtca attggggttg ggcaggctat gttttatggt
    21481 ccaggtgccg gtcaaatgcc aacagctaca gctgttgtgg cagatatgat tcagactgcc
    21541 tgcaccttac gtgaccatac agtctcagtc tttaatcgtt ttgctacaaa aactagacta
    21601 gctaagtctg aggatattat gagtccctat tactttgcta ttcaagcaac taataagttt
    21661 ggtcagctac tagagctaac aaggctatgt gatgtttgtg gcattagagt tgagcagctg
    21721 ttatcagatg agatagatag tgacaggtta gactttgtga tgattactca tgagatgagc
    21781 aaaaaggagc ttgcttgctt tacagcgcta ctacaggatc atcaggattt ccgtatgtta
    21841 agtacattta agattttagg agattgacat gaagatacgc gtacctgcaa cctcggctaa
    21901 tttgggacct ggatttgact caatggggat tgctgtttca aaatacctag aagttgacat
    21961 tttagaagaa cgtgaccaat ggtttattga gcatgatttg ggtgatattc caaatgatga
    22021 tagcaactta cttatccaaa cagcccttag gctagcacca aatattccag cacatcgtct
    22081 aaagatgacg tctgatattc cattggcacg tggcttggga tcgtcctcct cggtgattgt
    22141 cgctggtatt gaattagcta atcagctagg gcatttaaac ctaacagacg accgtaaatt
    22201 ggccatagca actcgtattg aggggcaccc tgataatgta gctccagcga tttttggtca
    22261 attggtaatt gcttcacaga ttggtaagga cgtggattac atcattgcgc cttttcctga
    22321 cctttctttg gtttgtttta ttcctgatta tgagctgaaa acctctgatt ccagagatgt
    22381 attgcccaag cagctatcgt ataagcaggc agtggctgct tcctcagttg ctaatcttgc
    22441 tatagctgcg ctattgaccg gtaatttgaa aaaggccggt cgggcgattg aaaatgacca
    22501 attccacgaa atctaccggc aaagattagt cagagagttc cagccgatta agcgagctgc
    22561 agcagctaat ggtgcttatg caacctactt atccggtgca gggcctgcta ttatggttat
    22621 gtgtcccaat aagaaaaaaa tggcgattta tgaggccatc gagcagctag gtctaattgg
    22681 tcagttggtg tctctagagc tggatcgtca ggggctgtgt cttgtctaga ctggcaaggt
    22741 actggtatgc ttgcctagta ggcttattgt tgatatcaga tggacttaaa gcttagtcat
    22801 tcaaatacat caaaaaagtg aggcttgatc gttttatcgg ctttcacttt tttcttgata
    22861 tgttatacta gagtagactt tgtgaggtgt gtgatgaatt atcaagaaac attagactgg
    22921 attcatggtc aggaaagatt tgggatcaag ccaggtgtaa aacgcatgcg ttgggtgctt
    22981 gagcagctag gtaatcctca agataggatt agaggaatcc atgtggtcgg cacaaatggt
    23041 aagggatcga cggtcaatga cctacagcat atttttacta gagcaggcta tgaggttgga
    23101 acctttacct cgccttatat catggatttt aaggaacgta tctgtctcaa tggtgagatg
    23161 atctcagaga ctgaccttgt taaggctgct aattgtattc gtccactaac ggatcgcctt
    23221 atcagtgaga caagtttggg tcctgcaaca gtctttgagc tgatcactct gatcatgttt
    23281 ctttattttg gtgagagtca cccggttgat attgctatta tcgaggcagg attagggggg
    23341 ctttatgact ccactaatgt gtttcaggcg atggctgtgg tttgcccgtc tattggtctt
    23401 gatcatcaag ctattttagg tgatacctat gctgacattg cctatcaaaa agccggtgtg
    23461 ctaaagggtg gtgaagacct tatttttgcc attgataaca aagaggccag acaggttttt
    23521 ctaaaaaaag cagagcagct tggcgtgcct atttgggaat ggcgtcgaca gttcaacatg
    23581 ctacagggtg aaggtggtta tcaatttaac agtcagcttg gtcagctgtc tcatctagtg
    23641 cttgcaatgc ctggtcagca tcaggtagcc aatgcaggcc tagccactat gacaagcttg
    23701 atattacagg atcggtaccc aaaggtaact gagtctgtta ttagagaggc tctggcaagc
    23761 agcttttggt tgggacgaac agaattgttg gcacccaacc tgatgattga tggtgctcat
    23821 aataatgaaa gcattgccgc cctgattgat gtgatatcat cagactatca ggataagcag
    23881 attcatattc tatttggtgc cattgatacc aagcctgtct cagatatgct gcagagtctg
    23941 gagcgtcttg gagatgtgca agtaacaagc tttcactatc ccaatgccta tcctttggag
    24001 gcttatccag ataggctaac aaaagtagca gattttagag catttttaga ccggcttgag
    24061 caagcagctg ctgatgattt tttcctgatt acaggctctc tttacttcat ctcagaggtc
    24121 aggcagtatt ggaaaaaggt attaagcaag taatgctttc tcacatcaac tcatcaaaca
    24181 agattaatca actaaaaagg ggaaaaccat tgccaatcaa tcaaaaaaaa gcagaagccg
    24241 ctatctatca attattagaa gctatcggtg aggatccaaa ccgagaaggg ctacgagata
    24301 ccccaaagcg tgttgccaag atgtatctag aaatgctctc agggctggaa caggacgcta
    24361 aggatgaatt tacagctgtt tttacagagc atcacgacga tttggtgatt gttaaggata
    24421 ttagctttta ttccatgtgt gagcaccatc tggtgccatt ttatggtaag gcgcatattg
    24481 cttatttgcc tagtgatggg cgtgtgacag gcttgagtaa gctggcaagg gcagttgagg
    24541 tgacgagcaa aagacctcag ctgcaggagc gtttgacagc tcagattgct aatgctcttg
    24601 ttgatgcctt gcagcccaaa ggggtttttg ttatggtaga agcagagcat atgtgcatga
    24661 ccatgcgagg tgtcaaaaag ccaggcagta agaccattac gacaactgct agagggattt
    24721 acaaggatag tagagacgac aggcgtgagg ttatgcaatt aatcatggag ggctagggta
    24781 tttatgacta ttggacatta ttcagccgct ggtgaggcag ctattatggg gattttaaat
    24841 gtgactccgg attcgttttc agatggtggc tcctatacta gtgttaatca ggccttggca
    24901 caggccgaaa aaatgctgtc agaaggagcg actgtcattg atattggagg cgagtcaaca
    24961 cgaccgggct gccaatttgt gccggcagaa gaagagattg cacgcgttgt tccaatcata
    25021 aaggccatta aaaaacggta tgatgtcctt attagcattg atacctacaa gacagaaact
    25081 gctagagcgg cccttgaagc aggagcagat atgctcaatg atgtctgggc aggactatat
    25141 gacggtcaaa tgctaagtct agccgccgaa tacgacgttc ccattatatt aatgcataat
    25201 caaaccaaag aggcttatgc tgatgttaca aaagaggttt gcagcttttt acaggctaga
    25261 gcagctgcag ccctcaaagc aggtgtcaaa aaagaacata tctggcttga tccaggattt
    25321 ggctttgcta aaaatgttga gcaaaatata gccttattaa aagggctaaa tgaggtttgc
    25381 cagttgggct atcctgttct ttttgggatt tccagaaagc gtgttgtaga cgccctactt
    25441 ggtggcggca ctaaagccaa ggatcgtgac ggggctactg ccgccctatc agcctacgct
    25501 attaataagg ggtgtcaaat ggtgcgcgtg cataatgtcg gtgctaacag ggatattgtc
    25561 tctgtattga gtcaattaag gtgagaaatg atggataaaa tcagattaga ggcttgtcgc
    25621 ttttatggtt atcatggtgc ctttaaggag gagcaggtct taggtcaaat ttttgtagtg
    25681 gatttagaat tatcagttga cttgatggct gcctctcttt cagactgcct agaggatact
    25741 gttcattatg gtttagtttt tgaaacagtc cgtcaaattg ttgaggaaaa gacctttacg
    25801 cttatcgaac gtttggctgg tgccatttgt caagagctat ttgcccagtt tttgcctatt
    25861 aaagcgatta aaatcgctat taaaaaagaa aatccaccga ttgcaggcca ttatcaagct
    25921 gtcggtattg aattggagag aaagagatga cacttgttta tttaggcttg ggaactaata
    25981 tgggagatag ggcaggctac ctacaggcag cagttaatgc cctatctaag ctgccagaga
    26041 ctgagttact gagacaatcc tctatctatc aaacagcagc ctggggaaaa acagatcaaa
    26101 atgccttttt gaatatggct tgccagctag atactaggct gacatcagaa gctcttttgg
    26161 cagctacgca ggctatcgag caggctctgg gacgagttcg tcatgaaaaa tggggcccaa
    26221 ggacaattga tattgacctc ttgctgtttg gtgatgagcc gtatcaatca gagaccttgg
    26281 ttattcctca cccttacatg acacaaagag cctttgtttt gattccttta ttagagattg
    26341 cacccgatgt gaccttacct ggtagccaga aaagcctgag gtcttacctt gatgctttag
    26401 agcaatcaga tgtagccttg tggtcacatg agtattcaaa taagttttct taaactgtcg
    26461 ttatttttac taaaatttga tataatagtg ctactctttg ctgatttttt gtcttatatt
    26521 aagaaatgat tgaagaaaga agaagattat gatagctgaa cttgaaggca ttgatattcg
    26581 agagaatgaa gccttaaaac attacaccta tacccaagta ggcggtccag cagatttctt
    26641 ggcttttcct agaaatcatt acgaactatc ccgtattgtt gattatgcca atcataatca
    26701 tattccttgg atggtccttg gaaatgccag taatctcatt gttcgagacg gtggtattcg
    26761 tggctttgtt atcatgtttg ataagctcaa cgccgtccgc cttaatggtt ataccttgga
    26821 ggcagaggca ggcgctaacc tcattgaaac aacaaaagtt gccaaatttc atagcttaac
    26881 aggctttgaa tttgcttgtg gcattcctgg aagcataggg ggtgctgttt ttatgaatgc
    26941 aggtgcttat ggtggagaga ttgctcatat ttttttgtcg gccaaggtct tgacaccaga
    27001 agggaaaata aaaaagatct cagccagaga gatggccttt ggctatcgtc actctgtcat
    27061 tcaagaaact ggtgatattg tgatttcagc caagtttgct ttaaaaccgg gtaatcatga
    27121 cagtatttgt caggagatga atcgcctcaa ccaccttcga aagctcaagc agcccttaga
    27181 atttccctct tgtgggtccg tttttaagcg tcctcctggg cattttgcag ggcaattgat
    27241 tatggacgct aacctaaaag ggcatcgtgt tggcggtgtt gaggtctcta aaaagcatgc
    27301 aggctttatg attaatgttg ctgatggctc tgccaaggat tatgaggact taattgctca
    27361 tgtcattagg acagttgagc aggcatctgg cgttaggctt gagccggagg ttcgtattat
    27421 tggtgaaagc ctttaatgat tgtgttatca aaaaagaaaa attgtggagg atttatgaca
    27481 attgactaag ccaattatca catttgacaa tgtctcaaag acatttgagg acagcgggac
    27541 acaggtccta aagaacatta attttgagct tgaggaggga aaattttaca ccctgcttgg
    27601 tgcctcagga tctgggaaat caaccatttt aaatattatg gctgggctgc ttgatgcgac
    27661 cagtggtgat atttatttag atggtgagcg tatcaatgat ttgccgacca ataagcgtga
    27721 tattcacact gtttttcaga attatgcttt gtttcctcat atgacggttt ttgagaacgt
    27781 tgcctttgct ttaaagctga aaaaggttga caaacaggag atagcaagac gtgtcaagga
    27841 aaccttaaaa atggttcagc tggagggcta cgaaaagcga tccattcaaa agctttccgg
    27901 tggtcagcgt cagcgtgtag cgattgctcg tgcgattatc aatcagcctc gtcttgtcct
    27961 attagatgag ccactttctg cccttgattt gaaattgaga acagaaatgc agtatgagct
    28021 gcgtgagctg cagcagcgac tgggcattac ctttgttttt gttacccatg atcaggaaga
    28081 agcactagcg atgagtgatt ggatttttgt catgaatgat ggtgaaattg tgcaatcagg
    28141 cacacctgta gatatttacg atgagccgat taatcatttt gtagctagct ttattggtga
    28201 atcaaacatc atcaatggta cgatgattaa agactatctg gtttccttta acgggaaaga
    28261 atttgagtca gttgatggtg gtatgcgacc caatgagcca gttgaggtgg ttattcgacc
    28321 ggaggattta caaatcaccc tgccagagga aggaaagctt caggtaaagg tagatacaca
    28381 gctctttcgt ggtgttcact atgaaatcat tgcctatgat gatttaggca acgaatggat
    28441 gattcactca acccgcaagg ccattgaagg agaagtgatt ggtttagatt tcacaccaga
    28501 ggatattcat attatgcgcc tcaatgaaac agaagaagaa tttgatgctc gtatcgaaga
    28561 atacgttgaa atcgatgagc atgcggatgg cttaatcaat gctattgagg aggagcgcaa
    28621 tgaagaaaac ctctagcctc tttgcagttc cctatttttt atggattgtc ctctttgtta
    28681 tggcaccggt tgcccttttg ctttatcaat ccttttttga catcgaagga cgattgacac
    28741 tagccaatta cgagactttt tttagctcat ggacttacct gagaatgggc ttaaactcta
    28801 tcttatatgc tggtatcgtt accttggtga cctttttgat ttcatatccc acagctttat
    28861 tgttaacgcg tttaaagcac aagcagctgt ggttaatgct tattatttta ccaacctggg
    28921 tcaatctgct cctcaaggct tatgctttta tggggatttt tgggcagcag ggtggtatca
    28981 atagcttttt aacctttatg ggcttaggac cacagcaaat tctgtttact gatttttcgt
    29041 ttatttttgt ggcctcttat attgagctgc cctttatgat tttgcctatt tttaatgctt
    29101 tagatgatat tgatgataat attatcaatg ccagtaagga cctgggtgcc aatgactacc
    29161 agaccttttc aagggttatc tttcctttgt cgctaaacgg tgttagagca ggggttcagt
    29221 ctgtttttat tcccagcttg agtctcttta tgcttacgcg tctcatcggt ggaaatcgtg
    29281 tgattacgct ggggacagct attgaacagc atttcctaac aacagaaaac tggggcatgg
    29341 gctcaaccat aggtgttgtc ctaattatcg cgatgattgt gattatgtgg ctaacaaagg
    29401 agaaaagtaa atgaaaaaat ttgccaatct ttacttagcg tgtgttttta ttttgctcta
    29461 tattccaatc ttttacttga ttgtttattc ttttaacaag ggtggagaca tgaatggctt
    29521 ttctggcttg acgctagagc attataagac catgtttgat gatagtcgct tgatggcgat
    29581 tttattgcag acctttgtgt tagcctttac aagtgccttg cttgcaacca ttatcgggac
    29641 ctttggggcg atttttattc atcagagtaa aaagaagtac caaaatgcga tactgtctgc
    29701 aaataatgtg ttgatggttt cccctgatgt gatgataggt gcctctttct tgattctctt
    29761 tacgtccttg aaatttcaat taggaatcct ctcggttttg atgagtcata ttgctttttc
    29821 cattccgatt gtggtcttaa tggtgcttcc tcggttgaag gaaatgaatc aagatatgat
    29881 taatgcagct tatgatctag gagcaaatca ctttcaaatg ctaaaggagg ttatgcttcc
    29941 ttatctgaca ccgggcatta tcgcaggcta ctttatggcc tttacttatt ccttagatga
    30001 ttttgcggtg accttttttc taacaggaaa tggctttaca accctgtctg ttgagatcta
    30061 ttcgcgtgct cgaaggggta tttcattaga tatcaatgcc ttatcaacga ttgtcttttt
    30121 gttctcaatt ctattagtca ttggctatta ttacatttca caggacaagg aggaaaagca
    30181 tgcgtaagct atactctttt ttagcgggaa ttatcggggt tatcttgctg cttgcgaccc
    30241 tgtcctttat tttgcagaaa aaaacgagct ctgctagtca atctgataag ctggtgattt
    30301 ataactgggg tgattacatt gatcccgctt tgctgaaaaa attcactaag gaaaccggta
    30361 tcgaggttca gtatgagacc tttgattcca atgaagccat gtacaccaag atcaaacagg
    30421 gtggaacgac ctatgacatt gctgttccga gtgattacac gattgacaag atgattaagg
    30481 aaaagcttct tgttaagcta gataagtcca agcttgttgg tctagataac attggtcagg
    30541 agtttttagg aaaaagcttt gatccgcaca atgattattc cattccttat ttttggggaa
    30601 cggtaggcat tgtctataat gaccagctgg tggataaggc tcctatgcat tgggaggatt
    30661 tatggcggcc agaataccaa aatagtatca tgctagttga tggtgctcgt gagattttag
    30721 gtgttggatt gaccacattt ggctatagcg ttaactcaaa gcacctaaag cagcttgaag
    30781 cagctgaaaa aaaactacag gccttaaccc ctaatgtaaa agcaatcgtc gctgacgaga
    30841 tgaaggggta tatgattcag ggtgacgctg ctattggtgt taccttctca ggagaggcta
    30901 gcgaaatgct ggacaataac gaccatctac actatgttgt accatcagag ggctcaaacc
    30961 tttggtttga taatctggtg cttcccaaaa caatgaagca tgaaaatgaa gcctatgcct
    31021 ttatcaactt tatcatgaag ccggaaaatg cagcacaaaa tgctgaatat atcggctatg
    31081 ccactcccaa tacaaaagcg aaggctttat tgccagatga tattaaaaat gacccagcct
    31141 tttacccaac tgacgagacc gtaaagaaat tagaggttta tgataattta ggctctaaat
    31201 ggcttggtat ttacaacgac ctttacctac aatttaagat gtatcgaaaa taggtcatgc
    31261 aagattgaag gagctattca ttggaaagct tcttcagtct tttttagctt ggtctggtct
    31321 caataatctc atgagattaa aaagaactag aatcttgctt tcgtctttga tacaatagta
    31381 gtggtttatt aaaatgaaag agatgacaaa atggaaaatc ataaaaacga gtttaccttt
    31441 tccaaacatt caatcatagc ctacgtttgg cgtggcattt tagtcgggat aattgctgga
    31501 gctattgtca gtttgtttcg cttattgatt gagatggtta gtgaggctgt tgttggctat
    31561 tatcaccaag ctcacagcaa tcgcatgctc cttgttccga tagcaggctt tagcttatta
    31621 gctgtttttt tagttggtct tttggtcaag tctgacgcca acattaaagg ctctggtatt
    31681 ccacacgtcg aaggggagct aaagggcttg atgtcaccca attggtggag tgtgctttgg
    31741 aaaaaatacc ttggtggaac aattgccatt tctatgggct taatgcttgg aagagaaggc
    31801 ccttctatac aattaggggc tatgtcagct aaaggcttag ctaagtacct gaaatctagt
    31861 cgtctagaaa aacgtgtctt gatcgctagt ggagcagctg ctggcttatc agctgctttt
    31921 aatgcgccta ttgcaggact gctttttgtt gttgaggaga tttaccacca tttttcaaga
    31981 ttagtgtgga tcactgcctt ggttgcaagc cttgttgcga actttatttc gttgaatatt
    32041 tttggcctta gacctgtttt ggccatgcct aaggccatgc cctttcttgc cttacatcaa
    32101 tattggctgc tcttaatctt aggccttgtg cttggctgtc tgggctttct ttatgaagag
    32161 gtcattttac attttcatag ggtttatgat tttcttggaa agagcttgcg cctagcgccg
    32221 cattttcatg ggctgattgt tgttgctatt atcctgctga ttggctatta tttgccacag
    32281 ctattgggcg gaggtcatgg tttgattatg tccttgtcag agcaaaagct accactgttg
    32341 actgttcttg cttacttctt tattcgattt ttagggagta tgtttagcta tggcagtggc
    32401 ctgcctggag gaattttttt gcctattcta accttaggtg ccttgtccgg aactattttt
    32461 ggattgattc ttcagcaaat aggactgtta gatcgccaga tgattcctct ctttttagta
    32521 ttgggaatgg caggctactt tgctgctgta tcaaaggcac ccttgacagg aatgatctta
    32581 gtgactgaaa tggtagggga tctgaagccc ttaatggcca ttgctgttgt gaccttcgtg
    32641 gcctacttgg tgatggattt gttaaatggt cagcctatct atgaagcaat gctagagaaa
    32701 atggctatca aacacccaac agatctagtg gagccgaccc tgatcgaatt acctgtaagt
    32761 gagaaaattg caggcagata tgtccgagac ctgaagctac ctaaaaacgt tttaattaca
    32821 acgcagctcc accataagaa atcacaggtc gtctcaggtg atacgctatt gatttcaggt
    32881 gctacgatct ttttggtggt caatgaagct gatacaggct ttgttcgaga ggtcttgatg
    32941 tagagcaagg tcggttaagc agtcagcagt agctgtgcta ccgatcaaag aagcagatca
    33001 gtgctttttc tcatctgatg aaaggtattg atttgctttt tttgtgttat taaacctttg
    33061 ttagcaagag ccatagcctt agcagtcgta tctgatgaat acctgctgtc tttttgttat
    33121 acttaagtat caatcaaagg agctttatat gctagaagtt atttcaaaag agctgcgcca
    33181 ttaccaaaag aataagcttg ccgcctatca aaaaaagaac caaggcatag aagctggtgg
    33241 aattgttttt gctggcgatt cgttaatcga atttttcccg ttgaaaaaat atttcaaaca
    33301 ggtctcaacc atttataatc gcggaattgc agggatagac agtcagtggt tgctagagca
    33361 tattgacagt catgtgaatg atctggagcc cagtcatgtg tttatcctga ttggctgtaa
    33421 tgatattggg cttggctttg atcaatcgca tatcgtatcg accattgttg atcttattag
    33481 tcgtattcgc agtcagtcta tttatactag gattagcctt ctgtccttat tgccggtttc
    33541 tgaaaatccc gcctatcagg cgactgtcaa gctaaggaca aatagggcta ttgatgagat
    33601 taatcaagca ttagcaatga taccagcgat tgaatttatt gatcttaacg cctgcttaaa
    33661 ggacgagact ggtggcttag cagctgctta tacggtagat ggcattcatc ttaatgccct
    33721 tggctatgaa cacttagctc aagctattag tccctatcta tgaaaggtaa aggctggagc
    33781 tgctaatttg taagggatct ttaaaaaaca agcactgatg aatcatcatt gaaacccttc
    33841 agagtgccga taggctgcac aatcaaagaa gcattaggtt tgtctatgac gcccttgtgt
    33901 taagctggct tttaggttta tactgcgaga aaatcagtca ttgggctggg agtctcaaag
    33961 cttagctgtg gtaattaaat gcgagctcct gctagcttgt gctgatcaag cagtatagca
    34021 aggagggact gaacttttag tctcagataa tattagactt tttatcctat attaaacgat
    34081 ttagtgtata ataaacagga aggagttaaa atgaaatttg aaaaaaaaca agtcttttat
    34141 gttgtgcttg cctttgtgct ttgttatgct attcaagcta attgggataa tggggctaat
    34201 attgtcacaa ccgtttataa gacaagcctg ccctttcttt atggagcagc agtcgcctat
    34261 attgttaata ttgtcatgag tgcctatgaa agagcttata cttataccct aaaacccttt
    34321 ccttttgcca tgaaggctag aagagggctc tgtatgcttt tggcatattt tacctttatc
    34381 agcttgatcg tatggattat ttctattgta atccctgatt tgattgcaag cattagctcg
    34441 ttaacgcaat ttgatacaag agctatcaag gaggtcatca gtgatttagg tcacaataag
    34501 ctgattgcac gtgccattaa ttacattggt ggagatgcta agctgacaga aacaattacc
    34561 aattatagcc agcagctgct caagcaattt ataggtgttc taaccggtat tttgacatcg
    34621 gttacagcag ttgcctcagc cattatcaat gtggttatca gctttgtctt ttccctgtat
    34681 gtgcttgcta gcaaggaaga gctttgtcag caggcaacta ccttaattga cacctatact
    34741 ggtaaatacg caaaggccat tcattattta gtgggtttgc tgcatagtcg ttttcgtggc
    34801 ttctttgtga gtcagacgct tgaagcaatg attttaggct ccttgactgc cattggcatg
    34861 tttatcctgc aattaccctt tgcaggaact attggagtct tggttgcttt tactgccttg
    34921 atccctgttg ttggtgcttc aatcggtgct gcgataggct ttgttttgat tatgactcag
    34981 tcaatgtcgc aggcagtcgt ctttattgtc tttcttgtta tactacagca aatcgagggg
    35041 aattttattt atcccagagt ggttggtggg tctatcgggt taccagctat gtgggtctta
    35101 atggcaatca ccattggtgc tgctctcaaa ggcattgttg gtatgatcgt tgcagtgcca
    35161 ttagcggcaa cgctttatca agtggtaaag gatcacattc ataaaaagca ggccttacaa
    35221 aatcgtcagt ccagctaatt aacagcatca gatcaaggaa aacgtctatt acaagaccga
    35281 tttcttggtc ttttatgctg tctgattgac tgcgtatggc cttattttta tgctgtggta
    35341 atgaaaaaag ccgtcttatt tatcgaatat cattagtgga ggtaataaga tgtattccat
    35401 caaaactgat cataaattaa tgcctagaga gcgtttgatt cgactgggtc cagaaaagct
    35461 aagcaatcaa gagcaactag cgatcctact taggacaggt aacaaggaaa agcatgtctt
    35521 agagttgtct gcttatttat tgtcaagctt agatagtcta gctgacttga agaaattttc
    35581 tttacaagaa ctacagcgct tatccgggat aggaaaggtc aaggctattg agattaaggc
    35641 catgctggag ctggcagacc gtattcagat agcgggacaa gcagtagcag atcctgtctt
    35701 atctagtgct caggtggctg aaaagatgat gattgaatta ggagacaagc agcaggagca
    35761 tttagtcgct atttatctcg atagtcaaaa taaaatcatt gaagaaaaga cgatatttat
    35821 aggaaccgtc agaaaatcaa ttgcagagcc tagagaaatt ctttattatg cgtgtaaaaa
    35881 tatggcgact agccttattg ttgttcacaa tcatccctca ggcctgacca agccaagcgc
    35941 aaatgactat cacttcacag aaaaaataaa acgatcatgt gattatttag gacttatctg
    36001 cctagatcac attatcgtta gtaagtatga ctactatagc tttcgggaaa aatcagattt
    36061 attttgagtt agaaactatg gataaaccaa tcaaagagcc ttaggtcttc ttctctaata
    36121 gcctgaagca gctctgggtg ccactggaca ccgagaaagg gaatatcagg attgcaggag
    36181 ataacagcct cgatggtgcc atcgttagga tcccttgcaa tcactcttaa gtcctctgcg
    36241 acctgcttta ggctctggtg gtgaaatgaa ttaatcagcg ctcttggacc atagataggg
    36301 tacaaaggtg aagtcttttc gatcactatc tcctgtgata aacagtcaga ggcagtcttt
    36361 tgccaatggc cctcaatgtg ctggtttaga ctgccaccta gagcaacatt tattaactgc
    36421 ataccgcgac aaatccctaa aattggtttt ttctgcgcta gggcttcttt aatgatggct
    36481 agctcaaaga tgtcacgctg gggtgaaaaa tcaccatcaa gtgcagctct tttttcatga
    36541 taatatttag gatcaacatg ctgaccacca ataagaatga ttttatcaac cattgcgaca
    36601 taggatttgg cagccgcctc atccccaatc ggaagaagta agggtaggcc accagatctt
    36661 gtcacagcct cgatgaagct tgttggagca taggagcaag gcaggttatc tagagccttg
    36721 gtcccccttt ggttagcagt tatcccaata attgttttag acacgacctt ctccattaat
    36781 caagatgatt ttggttcata aagtatagca aggtttgcaa ctcgctggtc aaatcaacag
    36841 attggacgat cacacctttt ggaacctgta agtgaagtgg agcaaagctt aaaataccgc
    36901 gaatgccagc ttcaatcagt tgatctgcaa cctcttgagc atagatgctt gggactgtta
    36961 gaatagccgt ttcaatgcct gaattatcca ggtgctcctt aatggtagaa atgccataaa
    37021 taggaatatc atcaggcgtt ttggtgccga ccataggatt atcatcagtg tcaaatccca
    37081 taacaatctg cattttgttt cgatcgtgga agcggtagtg aagaagtgca cgaccaatat
    37141 tgccgcagcc aactaaaatc acatgcgttg ttgagtgatc atttagcaaa tctgcaaaaa
    37201 aattcattaa ttttgtgaca tcatagccaa atccacgtcg gcctaattca ccaaagtaag
    37261 aaaaatcacg tcgaacagtt gcagaatcaa ttcccatagc atcagcaatc tgttttgagc
    37321 ttgccttttc aacctgatca gcataaaagc gtttaaaaat acgataatag agtgataagc
    37381 gttttgcagt cgcttttgga atagatttat caataaccac ttttgtagct ccttctattg
    37441 ttattttaat gttatctatc accattgtag cagatagatt gtgaaatatg caactatttg
    37501 accattcttt ttgtgttttt cgttataaaa tgacttgaca gcacaagcat tggtattttt
    37561 caaacccagt cacctcgagt ataaaaaagc agacaatgaa gcacttgccc tttaggtcag
    37621 ctgcgatggc tgggcttgtc ttgttaaagg caaatgtact gtcattgtct gatatttctc
    37681 tgagattaga agagctcttg tgtgcttagc attctttttt aatgaaaata tcacgctcaa
    37741 caaggctatc cattaaaaag taaaacttgt cctgtagtat gctatgctct tcagatttaa
    37801 aaatgttcac cagtcttaga ccggattggt ctgttatagc tagcttaaag ccatctaaat
    37861 ctttattaat cgtaattttt aaagggaagc cctcacccga attagggact ttttccagta
    37921 gtcgtgttaa ctgatagtga ccaatcttgg tctgactaaa ggttgtgtct cttagggtgt
    37981 attttttaat ctttgggcta atcctgtagc tgtatttgca gtctttaagg gcaatttctt
    38041 tttcaaatgc catatgatcc tcctaaaata tttttgagct gggttgctag tgcgataacg
    38101 tctttttgag tattttgctc tgaaaagcta actcgaatag cttctgtgag acgatgggac
    38161 tgcttgccga aataagctgc caaaacgtga cttggctcaa cagcaccagc tgtacaagca
    38221 gagcctgacg acacagcaaa gcctgctaaa tcaagctgag tcagtaatac atgattttgg
    38281 taaccaggaa agccgatatt aatgatatag ggaagatgac actcattatg attgagctga
    38341 taagaaatac cttctaattc actaagcaag agctgtgata gctctttagc atgctggtaa
    38401 tgctgtggca gccttgagac agcctcatct aatgcttggg tcatgccgac gatattaatc
    38461 aggctttcag tgccggctct ttgtttgttt tcttgattgc cgccatgtaa gaggggggcc
    38521 aactttaagc ctttattgta taaaaaacca gtcccctttg gtccatgaaa cttatgggca
    38581 gaggcagaga gcaaatcaat ccccaaatct gccggctgta ttgggacctt gccaatagct
    38641 tggacagcat caacatgaaa gacagcctga tgctgcttta gcatgctacc aacagcctga
    38701 ataggcagca aatctcccgt ttcgttgtta gcaaacatca tgctgactaa gattgtatcc
    38761 tctcttaagg cagcttggag ctgatttaga tcaatgattc catttttagc ctcaaggtag
    38821 gtcacctcaa agccaaatcg ttcttccaga taggccattg tgcttaacac ggaatgatgc
    38881 tcaatagcag ttgtaatcaa gtgtttgcct ttttcctgat gagctaaggc atagcccttg
    38941 atagcagtat tgttactttc agtacctcct gaggtaaaga taatgtggtt ttctgcagct
    39001 cctaggcagt tggcaatagc ttttcggcac tctcttaatt gtttgtttgc ctgccgccca
    39061 taagcatgaa tactagatgg gttaccaaaa tcatcagcca tagcttcagt catcgccttg
    39121 atagcagcct gactaagcga tgttgtagca gcattatcaa aataaatcat gattagttag
    39181 tgctttcagg tttgtaagaa aacagtggac ttagtggttt tctttcgtga atgcgaatga
    39241 tagcctctgc aattaaatca ctggcactaa gataggttac tgttttaggg atacgatttt
    39301 tagtcttgac agagtccgtg acaatgatct ctttgattgg agcagtctct aaaatatcag
    39361 ctgcacctcc tgcaaaaatc ccatgactag ccactgcata aatgtcagtt gcgcctgcac
    39421 attctaggat cttagctgcc tctgcaaagg tttttcctgt gttgagaatg tcatcaatca
    39481 agatagcctt cttgccagca acatcaccaa tcacatagcc ttcttcgcgc tcagcatcgt
    39541 cttgtgcata atcgataatg gcaattggag agttaagata ctctgctaag cttctagcac
    39601 gcttgatacc agaattttta gggctgacaa taaccgtatc aggtcctgag aggcccagtg
    39661 gataatagtg ctttgcaaaa agaggcactg taaataaatt atcaactgga atgtcaaaaa
    39721 agccttggac ctgaaccgca tgcaaatcaa gggttacaac gcgatcaatc cctgctttgg
    39781 tcagcatgtt tgcgaccagc tttgctgtaa taggctcgcg agactttgca acacgatcct
    39841 gacgcgaata accaaaatat ggcaaaacaa tattgactgt attagcactt gcacgcttac
    39901 aagcatcaat catgatgagc agctcccata ggttatcgtt gacaggaaag cttgttgatt
    39961 gaatgatata aatatcatca ccacgaactg tttcttcaat gttaatcatg atctcaccat
    40021 cagaaaattg acgagatgag acctttccaa gcggaatacc agcagcctta gaaatttttt
    40081 cagcgattgc gagatttgaa gtgagtgaga acagcttgat ttgcttgtca gcatatcgtt
    40141 cagtcatgat aaaattagct ccttacatta cattaacgat agaataacag gttaacagtt
    40201 attcaagatt acaaatagac agtactattt taacaaaaaa acagaaaaat ttcagtcttt
    40261 ctgttgattt tctgtcctct cctaggattt tttaagggtc ttgctaaagc gagcgacctt
    40321 gcttttggaa tatttaaagg tgatctgatg ctgggctaaa aagtggtcaa aatcaacctt
    40381 tcctcttaca ggatcagtca cctctagctc aagctcatag tctttgatac cagcatattg
    40441 attataatcc agcgctagct tgccaatagg agtatctgcc tctcgacgaa tggtagtcag
    40501 gtttccgaag gtttttatag cagataggtc aacgtcaaga gtgctgataa tatcaaggat
    40561 agctgatttt ggtagctgtc ctgtctgaat gatagctttt gcttgggtgt catcaagctc
    40621 taaattgtac tcgcgattac caaccttttc agggactttt aaggttaatt cagcaggagc
    40681 agcaacaaag gtgcgaatgc gaagtgacat tttatgagcc ttgagatcaa aatgatcagt
    40741 atcaatgtaa taatttgtct gggtaactgg tgggacatga gtcatttgag agaggaggcg
    40801 attatattcg tcctttgtca gtaaggtctt gtattcgatt tctaggttag tcatgcgaac
    40861 gttcctttta actatatttt atgctataat aaattgttat cttaatttta tattaatatc
    40921 cgaggtttga caagaaagga gagaaaggat ggctttagat tgggaagaat ttttggatcc
    40981 ttatatacaa acggttggcg aattgaaaat taagctgcgc ggtatccgaa agcagtttcg
    41041 caagcaaaac cgttattctc ctattgagtt tgtgactgga cgtgtcaagt cggttgagag
    41101 catcaaggaa aaaatggcct tgcgtggtgt cttggaagaa aatatcgctc aagatattca
    41161 agacatcgct gggcttagga ttatggtgca gtttgtggac gatattgagg acgttttgtc
    41221 cttgcttaga caaagacagg acatgacaat tgtttatgag cgagactaca ttagaaacat
    41281 gaaatctagt ggttatcgct cgtatcatgt tgtcgttgag tatcctgttg ataccattga
    41341 gggtcaaaaa aaagtattag cagaaattca aatccgtact ttagcaatga atttttgggc
    41401 aaccattgag cattccttga actacaagta cggtggtgat tttccagaag aaataaaaaa
    41461 acgattagag gttacagcaa aaattgcttt ggagcttgat gaagaaatgc gaaaaattcg
    41521 tgaagacatt cgtgaagcac aattgttatt tgatcctgta acacgtcatt tgagtgatgg
    41581 tgtaggaaat agtgatgaca cagatgaatt atacagataa agtaaagcgc gttgctatca
    41641 ttgcaaacgg caaatatcag agtaagcgcc ttgcctcaaa gctttttggc gtctttaagg
    41701 acgatccgag tttttaccta tccaaaaaaa atccggatat tgtgatttca attggcggag
    41761 atggcatgct tctatcagcc tttcatatgt acgaaaaaga attagacagg gtgcgatttg
    41821 taggcattca cactggacac cttggttttt acactgatta tcgtgatttt gaggttgatc
    41881 aattgatagc caatcttaga agagacaccg gtgagcaaat ttcttaccct attttaaagg
    41941 tagttattac gcttgatgac ggtcgcctgt ttaaggctag ggctctcaat gaagcaacta
    42001 ttaagcgtat cgagaaaacg atggttgcag atattatcat taacaatgtc aagtttgaaa
    42061 gctttcgtgg tgatggcatc tctgtatcca caccaactgg aagcacagcc tataacaaat
    42121 ccttaggtgg agctgtattg cacccaacga ttgaggccct tcagctaaca gaaatctcga
    42181 gcctgaacaa tcgtgtattt agaaccttgg ggtcctcagt gattattcct aaaaaagata
    42241 aaattgagct tgttccaaaa agactaggcg tttatactgt ctctgttgac aataaaacct
    42301 accacttaaa aaatgtggtt aaggtggaat attttatcgg caatgaaaag attcattttg
    42361 tgtcctcacc tagccacacc agcttttggg aaagggttaa ggacgctttt attggggata
    42421 gtgaatcatg aggtttgaat ttgttgcaac taaaaaaaca aaggtaaaga cccttttaaa
    42481 agagcacgat gtgtcaaagg gattgctcgc taagattaaa tacaagggtg gcaatatatg
    42541 ggtaaatggc gttgcgcaaa atgccattta tttattggat attggtgatg tggtggctat
    42601 tgatattcca aatgaggagt cctttgagca attgacagcg atttcgcatg accttgatat
    42661 tgtgtatgag gacgaacatt ttctcattct caacaagcct gctggctacg ctagcattcc
    42721 aagtgctatc cattctaata ctatagctaa ttttatcaag gcttattata tcaagcagga
    42781 ctatcccaat aaacaggttc atattgtgac gcgcttagat cgggatacca gtggcttaat
    42841 gctctttgcc aagcatggct atgcccatgc cagattagat aagcagctac agcaaagagc
    42901 tatcaataaa cgctattatg ctcttgtttg tggtcaggag aggcttccag atcaaggtga
    42961 gattatagct cctattggcc gtacggacga cagcattatc acaagaactg tcacgccaaa
    43021 gggaaagtat gctaagacaa gctacaaggt cattgcccgc tatcctgaaa atgtctctct
    43081 agtggatatt acgctgcaca ctggtcggac ccatcaaatt agggtacatt ttgctcatct
    43141 tggttttcca cttttgggag atgatctgta tggtggtcga ttggaccttg gcatgactag
    43201 acaggcgctg cattgtcacc atcttagctt tacgcaccca tttacagaaa gtagaagcga
    43261 tcatacaata tgcttgacag atgactttga gagcgttatc atagatttac agaaaaaaga
    43321 tagaggttag ttaatgagta ttcgtaattt atttggtggt ttaagggaaa aaattgtcgg
    43381 caaaaacatg aagattgttt tccctgaggg aaatgatgag cgtgttgtac gtgcagcagc
    43441 acgtctaaag tttgaaggtc ttgttgagcc aattattctt ggtcaggcag atgatattcg
    43501 cagcctgcta acacagctag gctttgctga gcagcactat acaatcatta acccaaatga
    43561 ttatgctgat tttgagaaaa tgaaagcagc ctttgtagag cttcgtaagg tcaaggcaac
    43621 gcttgaagat gctgatagac tgcttagaga tgtcaattac tttggtgtta tgctggttaa
    43681 gctaggctta gcagatggca tggtttcagg ggctattcat tcaacagctg atacggtgcg
    43741 tccggcgctt cagattatca agacaaagcc aggcatttct agaacatcag gtgtcttttt
    43801 gatgaatcgc gaaaatacag agcagcgttt agtgtttgct gattgtgcca ttaatattga
    43861 cccaactgct caggagctcg cagaaattgc ggtaaacaca gcagatactg cgaaaatttt
    43921 tgatattgat cctaaggttg ccatgcttag cttttcaaca atgggctctg ctaaagcccc
    43981 acaggttgaa aaggttcaag aggccgtccg tattgctaag gaattgaggc cagagcttgc
    44041 tttagacggt gagcttcaat ttgacgcagc ctttgtacca agtacagcag cgatcaaagc
    44101 ccctgattca tcagtggcag gccatgcgaa tgtttttgtc ttcccagatt tacagtctgg
    44161 aaatattggc tataagattg ctcagcgctt aggcatgttt gatgctatcg gaccaatcct
    44221 gcaaggattg aacaagcctg ttaatgattt atcacgtggc tctagtgcag aggatattta
    44281 caagctagct attattacag cagcgcaagc gcttgaaaat gagtctatca attaactgct
    44341 aatagccatt aagttcacaa ggcttagcta tagtagatgt tgcttaaaac gagttggata
    44401 agccagctcg ttttttcaga aagtgaggaa ggaaatgaca aagattgcat tagtaacagg
    44461 cgcctctgct ggctttggta aagccattgc agagcagtta atagcccaaa acatcaaggt
    44521 gatcggagca gcccgccgca tagaaaagct aagagagcta gaaggtattt ttggttctga
    44581 gaggttttat ccgcttcaaa tggacgtttc agaaccaact gccattgata aagcacttgc
    44641 agaattacct aaagaatggc aggccattga tattttagtt aataatgcag gactagcctt
    44701 aggacttgat aaggcctatg aggctgatgt cgccaactgg ctaaccatga ttaatactaa
    44761 tattattggg cttatctatt taacacgtca ggtattaccg caaatggtaa gcagcaacaa
    44821 tggcatgatc atcaatatcg gctcaactgc tggcactatt ccctatccgg gagctaatgt
    44881 ttatggggct tcaaaagcct ttgttaagca gttttcgctt aatttaaggg cagatttagc
    44941 aggaacaaat atcagggtga ccaatattga gcctggcctt tgtgagggaa cagagttttc
    45001 tcatgttcgc tttaagggtg accatgagcg tgttaaagca ctttatgcag gtgcacatgc
    45061 tattcagcca agggatatcg caaatactgt ctcatggatt attgatcagc cagagcatgt
    45121 taacattaac cgcgtggaaa tgatgcctgt ctcacaaagc tatggttctc agcctgttag
    45181 ccgtcatgac taagaattac aagagcagat gtaaaaggat tgtcgaagtg caacccaaaa
    45241 agacttaaag cctagctgtt ttatagcctg gctttaagtc tttttctcta atttttctta
    45301 gaaatgatcc gaaagagaag gtccagatgt gacatctgac cacccaacaa tggcctgccc
    45361 tgtttcttcc aaatagtgct gcagcatagg cttgaagtcc aaaatcatgt catagacccc
    45421 aacaaattgc ttggtatcat cgtacaaggc ttgatattgc tgcatataaa tatgatcctg
    45481 tgaagcagtc ggaataagat acagcttact gccagttgcc gccttgtgca aatcagtcaa
    45541 gatccaatcc tcaatgacat catgcttatc agaagcaaaa aaattgccat taaagcgatg
    45601 attatcaaag atgatctgcc cctgatgatc agcaattcta gcctgaaggg gaagataggt
    45661 taaaaaatgt ggggctaagg cttggtaaaa ttgcatgagg tatttagcaa gtcttaaagt
    45721 ttgctgacta tcagtaaagg tatgatcact aacggtaaat ccttgctctt tgtctgcctg
    45781 attaaaataa agtacaggta gtgaggcttc aaggttctga aaggtaaaaa tggcctgagc
    45841 ctttttgagc tgctcagtag tcagctgacg gacaatagtg atatgaaaca gatagctaaa
    45901 ctcttgtgat aaggtggtaa aaaaagtctt ttgcagatta ttcttatcat caaccagtgc
    45961 taaggtataa atcgttttag tcataaggct atcatagctt tattttgttt aaatagcaat
    46021 gaaacagcct tttagtctac agacttagtt gatagcttaa taaaagaaag caatatgaaa
    46081 aaatgattaa agcaaactag ttgacttgtt agtttaaact ttttataata aatcaaatga
    46141 gaagataata tgaggcttag cctaagctgc tgagcttatc tgataatcat tcttcttagc
    46201 actgagataa ccccctttat cgattaattg gagaatctat gatacgtttt aataatgttt
    46261 ccaaaacctt tggtcacacc aaggtgctgc aggagcaaag ttttcaaata cagaatcgcg
    46321 aattttttgt gctggtcggt ccaagcggct ctggcaaaac aaagctctta aaaatgatca
    46381 attgccttac tgaaccaagc tctggcgaaa ttctattaaa cggaaggcca caaaaagagc
    46441 tagatttgcg agatatgcgc ttatctattg gctatgttct tcagcaaatt gccctgtttc
    46501 caaaccttac agttgctgaa aatatcgcta ttattccaga gatgaagaag tggtcagaca
    46561 aagagattag aactaagaca gaggaattgt tagataaggt tggattgcct gcaagggatt
    46621 atctaaatcg ctatcccagt gatttatccg gtggagagca gcagaggatt ggtattgttc
    46681 gtgccatcat ttctcacccc aaggtgctgt taatggacga gccgttttca gccttggatc
    46741 ctatttcacg caagtaatta caggacttga tgttaagtct tcacaaggag tttgatatga
    46801 caattgtctt tgttactcat gatattgatg aggctatcaa gcttggagat cgtgtggctg
    46861 ttttaaatga agggcaaatt gttcaactgg atcgaccaga tgcgatcata gctgcgcctg
    46921 ctaatgattt tgtagcaagt ctatttggag gtcgtgatta tgcctagttt actgatgacc
    46981 ttttgggatc gttttggtga ttgggcaagg gcattaggag agcacttgca gatttctctt
    47041 ctttctttgc tggctgcctt gctgataggc attccgcttg cagctctgtt gagtaaaagt
    47101 aagcgctggt caaatatcat cttgcagctg acaggtgttt ttcaaaccat tccttcccta
    47161 gccttgttgg gactatttat ccctctaatg ggaatcggaa ctgctccagc tgtaacagct
    47221 ttggttattt atgccatatt tcctatttta caaaatacga ttactggctt aaatgctatt
    47281 gatccaagtc ttgtagaggc cggaacagcc tttggaatga ccaagtggga gcgactgaaa
    47341 atatttgaaa ttcctattgc tatgccagtt attatgtcag gtgttcggac ctcagcagtg
    47401 atgattattg gaacagccac cctagcttct ttgatcggag ctggcggctt agggaccttt
    47461 atcctattag gaattgaccg taataatgct cagctgattg tgattggtgc tgtgtcgtca
    47521 gccttgcttg cgatagtgtt taacagtctt ttgtgatacc ttgagaaggc ctcactgagg
    47581 cgtattgcga taagctttgc tgcgacctta ttactgctct taatttccta tactccaatg
    47641 tttgtcaagc ggtttgttaa tcagtcaaat actctggtga ttgctggcaa gctaggagta
    47701 gagccggata ttttgatcaa tatctataaa gagctgattg aagaccagtc caagcttaag
    47761 gttgaattga aacctaattt tggcaagaca agctttttat acgaggcgat taaatcagga
    47821 gatattgata tttatccaga atttacagga accatcacct ctagcctatt aaagaaaaag
    47881 cctaagcttt ctaatgaccc taatcaggtt tacttagctg ctaaggaggg gattgctgag
    47941 caggatcagt tgacgctttt aaagcccttt gcctatcaaa atacctatgc agtggcgatg
    48001 cctgaaaaaa tagctgacga atttaacatt caaagtattt cagatgtgaa gaaatatgaa
    48061 aaacagctaa aggctggttt tacactagaa tttaaggata gagaggacgg ctataagggc
    48121 atacaggata agtatgatct acatttatca gttgcaacga tggagccagc tcttaggtac
    48181 caagccattc agtcaggaaa cattcagctg acagacgctt attcaactga tgctgagatc
    48241 gtgaaatatc agcttcgagt cttaaaggac gataagcagc tctttccacc ttatcaagga
    48301 gcgccattga tgaaggcttc cttactaaga aagcaccctc atctcaaaac gattctcaat
    48361 cagttatcag gaaagattac tgaagaggag atgcaagcaa tgaactatga ggtgtccgta
    48421 aagggcagag cagctagcct tgtggcacat gactaccttg taaaggccgg tcttattgca
    48481 agaaccaaat aagcaggcat gctagtctta ttctggactg gcatgcttta tttatgtgat
    48541 ttttagtctg tctggctctg caaggtgtgt gccaaataac cgctcgtttg atgtgtggtt
    48601 attgatttag tagctaagga ttggaatctt aaaataaaat ccgaacgttt gtctaaaaaa
    48661 agctttaaaa attgacaaaa cataaacgaa aggataaaat aaattaagga aaggtaacat
    48721 tttacctagc gatgcctcgg acaagcttga ggtcatagga aggtcatttt atatagaagc
    48781 ttatgtcagc tgcagatcag ggaagtcctt gctggattag tagctgaatg ttgaaaaagg
    48841 agagaaatga tgtttaatga catgcctgta tttgattatg aggatattca attaattcct
    48901 aacaaatgta tcatcaatag tcgttcagaa gcagatacga gtgtaagact tggtaattat
    48961 acctttaagc tacctgttat tcccgccaac atgcaaacca ttattgacga aacaattgca
    49021 gagcagttgg caagagatgg ttatttctat attatgcacc gctttgatga ggaggggcgc
    49081 aagcccttta tccagcgtat gcatgagcaa cagctcatcg cctctatttc ggttggtgta
    49141 aaggattatg aatacgattt cgtctcttct ttgaaggagg acgcacctga gtttatcacg
    49201 attgatattg ctcatggcca tgctgatagt gtgatcaaaa tgattaagca tattaaggct
    49261 gagctgcctg agacctttgt tatagctgga aatgtcggaa caccagaggc tgttcgagag
    49321 ctcgaaaatg ctggtgctga cgcaacaaag gtcgggattg ggcctggtaa ggtttgtatc
    49381 acaaaggtta agacaggctt tggaacaggg gggtggcaat tagctgctgt acgttggtgt
    49441 gctaaggctg ctcgtaagcc gattattgct gatggcggta ttcgtactca tggtgatatt
    49501 gccaagtcga ttcgatttgg ggcaacaatg gtgatgatcg gttcactctt tgcaggtcat
    49561 attgaaagcc caggcaagat ggtagaaatc gacggacagt ccttcaagga atattatggc
    49621 tctgcctctg aatatcaaaa aggggagcat aaaaatgtcg aaggcaagaa gattttgctt
    49681 ccaaccaagg gtcatctagc tgatacttta accgaaatga agcaggattt acagtcatca
    49741 atctcatatg ctggaggcag agatttggag agcctgcgtc gtgtgaatta tgttatcgtg
    49801 aaaaattcta tttggaatgg tgactctatt taaagccttg gctaaagacc tagtctaaat
    49861 aaggataagc aagctgattg atgctgagaa taagcacagc gtgtctatag gacgcctgaa
    49921 tgtctagtag ccagtaaagc ttttaggctt gctgattgga taggtcattg tgcctatgtg
    49981 cagcagggct ctagggactt agataaaaag gagacatgat gaggttactg gaggagcgta
    50041 tcctagctga tggaactgtt ttaggtgaga cgattttgaa ggtggatcaa tttttaacac
    50101 atcaggttga ctatcgcttg atgaaggaaa tcggtagagt atttgctgat caatatgctg
    50161 atttgggcat taccaaggtg gtcaccattg aagcctctgg tatcgcacca gcagtttata
    50221 ccgcagaagc tcttgaggtt ccgatgattt ttgccaaaaa gcacaaaaat atcacgatga
    50281 cagagggaat tttaacagca gaggtttatt cctttaccaa acaagtgaca agtactgttt
    50341 ctattgcagg aggactgcta tcaaaagaag atagggtttt gattattgat gactttttgg
    50401 ctaatggtca agcggcaaaa ggcttgattg atatcattca tcaagcaggg gccaaagctg
    50461 ttggcatagg cattgtcatt gaaaaatctt ttcaggctgg acggcaattg cttgaggatt
    50521 tgggagtaga ggtcacttca ttggctcgta ttaagcattt tgacaatgga atagtaagct
    50581 ttttggaggc tgatgcctga tgactgcttc ttatctctca gcattaagct ttttacttgt
    50641 atagctatac cagctttatt tcagtagcta ttggctggtg ataagggata ttggtatggc
    50701 ggtgcattac ggcgagccgt gggcagttgc ccttgcggct ttacgattta gtatagacta
    50761 tcaagaattg actgcttcct ttttatcgag atgaatcatt agacagacaa tcatgatttg
    50821 gcgtgaaggc tgctttcagt aaacattaca tcatcaaaaa tcagctaggt attcacttag
    50881 ctgattttta gtgcttataa tgtagccgaa aggctccctt taacccgtct gagatagtaa
    50941 cctgaccatc tttggtaatg ataatgcctt ccacctcagg cagcttattt agctgactta
    51001 ggacaaagga atgctctaag ccaaaaagac gactactcca tagctcacca tcaagtgaga
    51061 attggctgac aatggttagg ctagccatat tggtcttgat aggatagccg ttgtgaggat
    51121 caagaaggtg atgataagtt ttgtctttga tttgtaattg tctctcgccg attcctgagg
    51181 ttactacaga tttattgtta accttaatca cgccgacatg ctgtcctctt ttttgattgg
    51241 tctgctggat cccaacgtaa aacaagccat tatgtcgttg cttgttggtg ccatgcacaa
    51301 ggacatttcc acctagattg ataagagcag cagtgatacc gtctttaata agaaatgcca
    51361 tgagcttatc agcaatatag ccctttgcta gggcacctaa gtcgatagac atgccctttt
    51421 ctttcaaaaa aatacttcca aggctttgat cta
//
LOCUS       DARYVE010000005        50719 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYVE010000005 DARYVE010000000
VERSION     DARYVE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50719
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            175..963
                     /locus_tag="TVW25_000248"
     CDS             175..963
                     /locus_tag="TVW25_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1377923.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TVW25_000249"
     CDS             972..2141
                     /locus_tag="TVW25_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1377924.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TVW25_000250"
     CDS             2144..2347
                     /locus_tag="TVW25_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377925.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TVW25_000251"
     CDS             2479..3912
                     /locus_tag="TVW25_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1377926.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5110)
                     /locus_tag="TVW25_000252"
                     /pseudo
     CDS             complement(3942..5110)
                     /locus_tag="TVW25_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5166..5807
                     /locus_tag="TVW25_000253"
     CDS             5166..5807
                     /locus_tag="TVW25_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1377927.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5928..6854
                     /gene="cysK"
                     /locus_tag="TVW25_000254"
     CDS             5928..6854
                     /gene="cysK"
                     /locus_tag="TVW25_000254"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1377928.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7241..7603)
                     /locus_tag="TVW25_000255"
     CDS             complement(7241..7603)
                     /locus_tag="TVW25_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1377929.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7603..9003)
                     /locus_tag="TVW25_000256"
     CDS             complement(7603..9003)
                     /locus_tag="TVW25_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1377930.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(9036..9677)
                     /locus_tag="TVW25_000257"
     CDS             complement(9036..9677)
                     /locus_tag="TVW25_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1377931.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9670..10674)
                     /locus_tag="TVW25_000258"
     CDS             complement(9670..10674)
                     /locus_tag="TVW25_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1377932.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10671..11363)
                     /locus_tag="TVW25_000259"
     CDS             complement(10671..11363)
                     /locus_tag="TVW25_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1377933.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYIIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TVW25_000260"
     CDS             complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TVW25_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1377934.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13388..14128)
                     /locus_tag="TVW25_000261"
     CDS             complement(13388..14128)
                     /locus_tag="TVW25_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1377935.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TVW25_000262"
     CDS             complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TVW25_000262"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1377936.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15478..16413)
                     /locus_tag="TVW25_000263"
     CDS             complement(15478..16413)
                     /locus_tag="TVW25_000263"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1377937.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16480..18864)
                     /locus_tag="TVW25_000264"
     CDS             complement(16480..18864)
                     /locus_tag="TVW25_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1377938.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18928..19245)
                     /locus_tag="TVW25_000265"
     CDS             complement(18928..19245)
                     /locus_tag="TVW25_000265"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1377939.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TVW25_000266"
     CDS             complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TVW25_000266"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1377940.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(20058..21668)
                     /locus_tag="TVW25_000267"
     CDS             complement(20058..21668)
                     /locus_tag="TVW25_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1377941.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21825..22310
                     /locus_tag="TVW25_000268"
     CDS             21825..22310
                     /locus_tag="TVW25_000268"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1377942.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22455..23906)
                     /locus_tag="TVW25_000269"
     CDS             complement(22455..23906)
                     /locus_tag="TVW25_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377943.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPEVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23920..25074)
                     /locus_tag="TVW25_000270"
     CDS             complement(23920..25074)
                     /locus_tag="TVW25_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1377944.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25138..25506)
                     /gene="rnpB"
                     /locus_tag="TVW25_000271"
     ncRNA           complement(25138..25506)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TVW25_000271"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TVW25_000272"
     CDS             complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TVW25_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1377945.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25964..26479)
                     /locus_tag="TVW25_000273"
     CDS             complement(25964..26479)
                     /locus_tag="TVW25_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1377946.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26555..27163
                     /gene="recU"
                     /locus_tag="TVW25_000274"
     CDS             26555..27163
                     /gene="recU"
                     /locus_tag="TVW25_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1377947.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27150..29315
                     /locus_tag="TVW25_000275"
     CDS             27150..29315
                     /locus_tag="TVW25_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1377948.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TVW25_000276"
     CDS             complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TVW25_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1377949.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TVW25_000277"
     CDS             complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TVW25_000277"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1377950.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32202..33662)
                     /locus_tag="TVW25_000278"
     CDS             complement(32202..33662)
                     /locus_tag="TVW25_000278"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1377951.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33938..35332)
                     /locus_tag="TVW25_000279"
     CDS             complement(33938..35332)
                     /locus_tag="TVW25_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1377952.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TVW25_000280"
     CDS             complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TVW25_000280"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1377953.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36429..36656)
                     /locus_tag="TVW25_000281"
     CDS             complement(36429..36656)
                     /locus_tag="TVW25_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1377954.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36766..37509)
                     /locus_tag="TVW25_000282"
     CDS             complement(36766..37509)
                     /locus_tag="TVW25_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1377955.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37509..38312)
                     /locus_tag="TVW25_000283"
     CDS             complement(37509..38312)
                     /locus_tag="TVW25_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1377956.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38689..39516)
                     /locus_tag="TVW25_000284"
     CDS             complement(38689..39516)
                     /locus_tag="TVW25_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1377957.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            40024..40479
                     /locus_tag="TVW25_000285"
     CDS             40024..40479
                     /locus_tag="TVW25_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377958.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41120..42463)
                     /locus_tag="TVW25_000286"
     CDS             complement(41120..42463)
                     /locus_tag="TVW25_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1377959.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42546..43553)
                     /locus_tag="TVW25_000287"
     CDS             complement(42546..43553)
                     /locus_tag="TVW25_000287"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1377960.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43555..45810)
                     /locus_tag="TVW25_000288"
     CDS             complement(43555..45810)
                     /locus_tag="TVW25_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1377961.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TVW25_000289"
     CDS             complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TVW25_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1377962.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TVW25_000290"
     CDS             complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TVW25_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1377963.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47194..47610)
                     /locus_tag="TVW25_000291"
     CDS             complement(47194..47610)
                     /locus_tag="TVW25_000291"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377964.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47630..48877)
                     /locus_tag="TVW25_000292"
     CDS             complement(47630..48877)
                     /locus_tag="TVW25_000292"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1377965.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TVW25_000293"
     CDS             complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TVW25_000293"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1377966.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50296..>50719
                     /locus_tag="TVW25_000294"
     CDS             50296..>50719
                     /locus_tag="TVW25_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1377967.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14988 a        11590 c         9689 g        14452 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctg accttgcgct
     4381 ctaaatctct tgtagaggtt gctgttaggt atactgtcac tgcatctgct tttgcagcct
     4441 gatgagcagc atggtttaat tgacgattat tgacaaaggg gaaggcatct acttcgtcaa
     4501 taatgagcag atcaaaagca tggtaaaagg tcatcaattg atgtgttgtg gcaacgataa
     4561 tggggcttct atgataaacc tctgactcag catgcataag gcagacttga caggaaaagt
     4621 cccgcgatag tcgtttttca agctctatgc aaacatcaac tcgtggacta gcaatgcaga
     4681 cccagccacc cttattaaca actgctgcaa tagcttcata catcatctct gttttgccag
     4741 caccagtaac cgcatgaact aaggtgtctt gcttgagctt aacatggtta gtaagctgat
     4801 gagagatagc tgcctgatat gtcgtgagct gtccttgcca cctcagataa tgtccctttg
     4861 gaaaagaagc cggtggaaaa tagagcaagg ggcgatcaga ttggtttcga ccaaaaacaa
     4921 gacaggctct acagtagtaa gcaccgctag gcagctgatg agccttctca attaaactgc
     4981 tacagcgttg gcagtataac gttccctttt tagtgatcat gctttgtaag ctgcaagccc
     5041 aggcagaaac agcctttggg cattgccttt cgggtaaaag acgtccatag taattttcga
     5101 tattctccat accttattat ccgaattatt ttgctaaata tcagcatttt ttgtaaaatt
     5161 ttcttatgga agattataaa actattatga ctgatgggct ttttgaggaa agcatcaaaa
     5221 aatctcgctt tatttgccaa atcaaacgcg tctacacaga agaggaggcc agagccttta
     5281 ttgctgacat caaaaaaaag cactataagg ccaatcattc ctgctctgct atgattatcg
     5341 gagacaaagg acaaaccaag cggtcaagcg atgatggtga gccatctggt actgctggta
     5401 ttcccatgct atctgtctta gaaaggcagg aattaaccaa tcttgtagct gttgtgacac
     5461 gctattttgg aggtgttaaa ttaggagctg gagggctcat tcgcgcttac tccggcgtaa
     5521 ctgcggcagc tattcaggcc ttaaaggtcg ttgaggtaaa aaaacaaact ggactagcaa
     5581 tcagcctcac ctaccctcaa taccaaatct atcctaattt tctggagcaa gaagcattga
     5641 ttgaaatgaa taccgaattt tctgatgtcg tcagaacagc tatttacttt gatcctgagc
     5701 gcttggagag tatttctaag gcattgattg agcattatca tggcaaggtt tcctttgaag
     5761 agatcgaatc gcaaaggatt gaggtccctg ttttgcctgc caattagcat gaacagtgat
     5821 agcgtctctt tatcactacg atagtaaatg gctattttac tttgtcgatt attagctata
     5881 tacttttata taagcatgta ttgatacaag gataaaaagg aggacctatg tcaaagctat
     5941 atcacaacat tacagagttg gttgggaaaa cccctattat taaattgaga aacaccagtc
     6001 cagaggaggc tgccgatatt tatgtcaagc tagaagcttt taatccaggc tcttcagtta
     6061 aggatcgcat agcacttgca atgattgaag ctgctgagaa agcaggcatg atcaagccag
     6121 gtgatacaat cgttgagcca accagtggca atacagggat tggcttatcc tgggttgggg
     6181 ctgcaaaagg ctaccgagtg ctcattgtaa tgcctgagac aatgagtatt gaaagacgtc
     6241 aaatcattca agcttacgga gcagagctcg ttttaacccc aggtagtgat gggatgaaag
     6301 gtgcgattgc taaagcagaa gagattgcca gagagaccgg tgcttggatg ccctcgcaat
     6361 ttgacaatcc tgcaaatccc aaggttcatg aagagacaac agggcaagaa attatcgcgg
     6421 tttttggaga aaaaggactt gatgcctttg tttctggtgt gggaactggt ggcactattt
     6481 ctggcgttgc gcatgcctta aaggctgtta atcctgatat ttctatctat gctgtggaag
     6541 cagatgaatc tgccgtctta tctggtgaag agtcttctcc gcacaagatt caagggattt
     6601 cagctggctt tatcccaaat accttagata caaaggccta tgaccacatc attcgagtag
     6661 cgtcagaggc tgcccttgcc actgctcggt caatcggggc taaggagggc tttcttgtag
     6721 gcatttcttc tggagccgct gtttatgctg ctatccaagc tgctaaggag cttggaaaag
     6781 gtaaaaaggt cttagctata ttaccagata atggtgagcg gtacctgtct actgcccttt
     6841 atcagtttga ttagaataat catataagca ccagccctag cagctagaat aagctttcaa
     6901 gcataaatca tcgctcttac ttagtcacca ttaaaggcca gtcagctagc atatggaaaa
     6961 atgcttactt tgattccttt ttaacaataa acatagcata ccacgcctaa gcgccccaga
     7021 gcttctagct tcttggaaat aggctttcct agccgctttc accacagtaa aaaagactca
     7081 agctagtagg ctaagatgtt caaagaggac tagcaatcac aattggcttt ttttgaagat
     7141 agctttgaga taagtaaggt gactggtcca gagctgatag caaaaaaccg aggaacagtt
     7201 catatagctg tttctcggtt ttttatgttt ccaagtctgt ttacgatttt tcctgcttaa
     7261 agtggtctaa gccttcctca atccaattgg gtaagctggc ttcaagaggc ttaaagccaa
     7321 tcttataacg gctgtttgaa aagcgatgat gacttgacac atgatgcttt tcctcctcca
     7381 aagttctcaa ggacaggctg accttatgac tgtattcgtc atagtcaatg acctgaacta
     7441 aaaccgcctc accaagtctt aggatctgat gaatattatc aataaatccc gtcttaattt
     7501 ctgaaatatg aatgagacct gttgtcccat tttcaagggc aacaaaggct ccatagggtt
     7561 tgattcctgt aatggtccca tgcagcttat cgccaatttt catcaatcaa atacctcgat
     7621 ggcctcaatg acaacgtcct cttttggctt gtcttgtgcc cctgtttcga cagcagcaat
     7681 gttatccaag acctgataag aggcttcatc agccaactga ccaaatactg tatggcgacg
     7741 atccaggtaa ggagtccccc catgttcagc gtaggctgct gcaatgtcct ttggccagcc
     7801 accacgctct aattcctttt gagaataagg aaggcttgta ttttggacga taaagaattg
     7861 gctgccgttt gtatttggtc ctgcattagc catcgaaagg gctccgcgaa ggttgtacaa
     7921 ttcctctgaa aactcatcct caaagctttg accatagatg gattgcccac ccattccagt
     7981 gccagtcgga tctccacctt gaatcataaa atctgcaata atacgatgga aaataacacc
     8041 attatagtag ccttccttag ctagacctaa gaagttagca actgtttttg gagcatgctc
     8101 tggaaataaa gccaatgtca gctcaccatg atttgttttc atcaccactc ttggtccttc
     8161 atggccagcc aaatctagct gcggaaaatg taattctttg tcaatcaaac ctaattcctc
     8221 caaggcatat aaaatgccgt tttcttcaac tgttttagta ataaaatctg ctttttcttg
     8281 taattgtggg tgagaaaccc ccatagcaat gctgatgcca gcataatcaa atagctctaa
     8341 atcattgagc tcatcaccaa agaccaggat attttcaggc cttaagccca aatgctcaac
     8401 aacctttgat acacctagag ccttagaggt gccctttagg accacatcag aggagtgatc
     8461 atgccacctt actaggcgaa gctgctcagc caattcaaca ggtaattgca ggtcatctcc
     8521 cttgtcctca aaggtccaca tttggtagac atcatggtgc tcattgtaat ccgggcatac
     8581 ctctagtgtg gagtaaacct tatcaatagc atcactaatc atctcgttac gagctgataa
     8641 gacagcctcg tgacgtcctg ccatgccata atcaatgccg actgcattgg cccatttttt
     8701 ataggctaca acagtgtctg ctgggatagg tgcctgaaag ataatgtttt tttgattgtc
     8761 cttcacataa gcaccattta gcttaacaca ataatctgcc tgtaaatcct gaacctcctt
     8821 gggcacacca tatctggcgc gacccgaagc aattcctgtt aggatccctt ttttcttgag
     8881 ctctttgaaa accctctgga tagactctgg catatagcct gtgttcttta cgcgcagggt
     8941 atcatctatg tcaaagaaaa ccatcttgat tttcttggcc ttatacttta gttttgcgtc
     9001 catactttcc tccatgcaat agtactatta tagcattaat gatcatcttg aggcactaaa
     9061 tgatgtcgga aagcgtatac aacagcctga gtacgatcat caacctgcaa tttggctaaa
     9121 atatttgaca cgtgagtctt aactgtcttc aaggaaataa aaagctcatc agcaatggtc
     9181 tggttatcat agcccttggc caataaatgc aaaatatcgt attcacgcgc tgtaagctct
     9241 tcatgtaaat taggctgctg atcatgtgcc ttaatcttct tgtcaacctc cgtttcaatg
     9301 gcaagctcgc ccttagcaac ctttctaatg gcatttaaga tttcagctgc acttgatgtt
     9361 tttaacatat agcccttagc tcctgcatca atgacagggt aaattttttc attatcaaga
     9421 taggaggtta acaccaacac ccttgcttcc ttccatttgg agagtatttc tagggtcgcc
     9481 tctacacctc ctaattcagg cattaccaaa tccataacca cgacatctgg tctcaattca
     9541 agggcaagct caactccctc acgaccatta gaagcctcac ctatgacatc aacatcttgc
     9601 tgcaaattta agaagctttt taagcccatt cggaccattt catggtcatc aactaatatt
     9661 acggttatat tactcatctt catctcccat cacaagtggc agtctaatgt ccatcgaaac
     9721 gccctttcct ttttgactaa tcaaacgaag cgttccagcc aggtcattca cacgatcttc
     9781 aatattttta aggccatagc ttaattccct aacctgaccc atgtcaaaac caaccccatt
     9841 atcaaccatt tttagctgta gttctgttgg tgtttggttc aagtacacct caaggcggct
     9901 cgccttagca tgcttgaggg tattgctgat aaattcctga gcgatcctaa agagattatc
     9961 ctctatggcc tttggcagag tgccaatatt ttctttatag acaacctcaa tgccgctttt
    10021 atcagttagt tccttgagaa tcatcgtaaa gccctctgac aggctacgat ttgccaattc
    10081 tgtcgggcgc aggtgcaata ataaaatgcg taaatcattt tgagcatttt gcagcatggc
    10141 ttcaacagta actaattgtt gctgtagctg ctccttatcc atctgatcta ggctcataga
    10201 aacccctgac aaaatcatcg acgaagcaaa caattcttga ctaacagtgt cgtgcaggtc
    10261 tctagcgatt cgtttacgct cctgttgaac aattttttga ctatctaaaa tataagcatt
    10321 ctcttttttc tggatattgg ttgttatatg agacattttc gcagaaagtc tggtcaaatt
    10381 cgtgttgatt tcagaggtct cctccaaatg aattctttga ttgttgagaa tcctgcgtaa
    10441 atttttattg atgctccgct tgctattatc atctaaaata atccacaaca aaagcaacag
    10501 caaggttaca gagatgataa gcagcacaac tgaaaacacc aagcgctcta gctgccataa
    10561 atggctccgc aagtagtcaa aggtgatccc cagattatcc atcacaacaa aaacaattga
    10621 taaaatggtt atagtcgaat aaagccagac caaagcataa tacctttttt tcatcgtcta
    10681 gccacctcga catttcctgc tatagtggat acgataatct taaccttctt taaactgctg
    10741 tcctcggcct ctcctagggt gatggattca tttcgtaaat cgtactcttg aagctcaaaa
    10801 aaatcaacac tagcatagat agagctgacc tctaaggtaa cagccacatc aataggcact
    10861 aggatctttg tgttgccaaa gatctttctg ataatgatga cattgtccat tccagtcaca
    10921 atcacatttg tcagatcaat cgtatcattg ccagaggcac gaataatatt gatatcctca
    10981 aaggaataat aatcactttc atagttagct gcgccaagcc attgattttt gacctgtcgc
    11041 acagtcattt tttcttctgc aaaccgaatg agggcaaatc gattcttctt ttttacctgt
    11101 gaaaaatgat tgataatcac atacacaatc cccaacagaa ccgccataat aatataaggg
    11161 ttcagcataa aaattaagaa taaaagcaat aagctaactg ttagcaaaaa gctattgcgg
    11221 gtatcttgat tataaaaacg cagagccaat aaaatcaaga ccaaaattaa aataaagctt
    11281 gataagtcgt tggccaaaat ggtcataatc cccatagcca gcagcatgca ttcaacaagc
    11341 agaaagaatt gaaatttttt cattagactc cttccattac cctgacattt tatcaaaaat
    11401 taagcaaaaa ttcacccttg agtggcattc tagtaaaaaa gaatacctag cttagcaact
    11461 atgggcaagc cagatattct atatcctatt tacgtttacg gtgttgtaac agcgtcattt
    11521 tgacctaatt cggtatgact gcttgagtct gttgtatctc cagctgatgg attaggagcc
    11581 gaggtatcag agctcgatga gctgcttgat gcacgtgtct cctcagggta gaggtagagg
    11641 ctaatatcac ccttttcaga aaggctaatc tgggtaccat aatacggtgt ttgcccactg
    11701 acaaccgcct ttgagcttgg ggagctcacc tgcacaaagc ctgtcggaga gctggagctt
    11761 ggtacatagg ccttgattct tgcggcatca attcctaaag ctgttagtgt attgactgca
    11821 tctgcatagc tgtactcagt taccattggc atgatgactg tatcacccac tgctacactg
    11881 agggtaatct tggatttacc agctgggtta aatttttctc ctgcgcttgg agactggcta
    11941 ataacggtgt tttcagggta ttcatttgtc acgatacgct caatcttgat ttttgacttt
    12001 ggtacgccat aggtctcagt cagactggtc atcacatctt gataatcctg tcccttataa
    12061 ttttccatct caaagccttt atttccgatc gaaaggtaaa ggtcaacgct ggagcctttt
    12121 cgcttagctg agccagcttg aggatttgtc ttaaccacct gatcctcact aactgtgtca
    12181 ctttcaatct gatggacctt accgaccttt agtcccgcct cctccaagac ctgcttggca
    12241 gcattgagac tagagcctgt cacatcagga accttaaccg tagttggctt ggtcaagacc
    12301 aaataagcaa aaagagccac accaacaaca aaaaaggaaa acaagatttt taagagtgtt
    12361 cctagaaaac gcccattttt tttctttttt tgaggctttt gcagagtatc catctggcta
    12421 gtctgctcaa gtctagcatc aactgccgca gatgcctgac tagcatttga taccttaggt
    12481 gctgttacag gagtcggtgt tacctttggc aagggctttg tgctttcgac atcatcaaag
    12541 acaaccttac gctcacgact gcggttatag ctaagggctg tcatcaaatc cctgctcatc
    12601 tcaaaggtcg agcgataacg gtcacttagc tttttggcag tagcccgaat aacgacgttt
    12661 tccaaggctt gaggcacatt aggattttca tcaatgatag agggcagcgg cttttgaaaa
    12721 tgctgcaaag caatcgtcac agcgctatcg ccatcataag gaatatgccc tgttagcatt
    12781 tcaaagagca taattcccat cgcgtaaata tcactttgaa tcgtcgcttt agaaccacgc
    12841 gcttgctcag gtgagaggta atgcacactt cctagcatag aatttgtctg ggttagactg
    12901 gtctctgcaa aggcaacggc aatcccaaaa tctgtaacct taacaacact tgatttggtc
    12961 aaaagaatgt tttgaggctt taaatccctg tgaacaattc ctttttggtg ggccagagtc
    13021 atggcagaaa gaacctcttc catgattctc accacctcat tgttagataa tggcgcatga
    13081 tcctgaatgt attttttcaa gtcagagcca tcaacatatt ccattactaa aaattgctgt
    13141 ccgtcttcct cgcctatatc ccgaatggca acaatattgg ggtgatttaa ttcagccatg
    13201 gctcgcgctt ctctttgaaa acgcgcaaca gcaacctgat ctgtttgata attggtccgc
    13261 aagaccttaa tggcaacgtc ctcattatcc agaatcaaat cgtttgctaa ataaacatcc
    13321 gccataccac cgcggcctat agattttaga atgcgataac gaccagcaaa tagcttgcca
    13381 atctgaatca ttctgcttcc ccgctttcct tatgcaccaa agcaacggtg atgttgtcta
    13441 ggcctcctct ttggtttgcc aggtcaatca aggcttgatt tttctcatca aggctgatgt
    13501 cttgacataa tatgtcaaca atctcctcat tagcaatcat attggttaag ccatcactat
    13561 taatcactag gtaatcgccc ttttctaaaa ccttgacacc taagtctggc tctaccggtg
    13621 aagcttgacc tatagattgt gtgatgatat ttttttgtgg gtggctagca gcctcctctt
    13681 cggtaatctg accagccttc actagggcat taaccaagga atgatcactg gttaaaagac
    13741 tataatttcc ctcatgaacc aagccgatac gagaatcgcc aatatgggca taaatcgcat
    13801 tagaatctac tagagcaact gcctcaacgg ttgttcccat tcccttatag tcttcagatt
    13861 gtcccaagtc gtagatacgt tggttctctg cttcgatggt tgttaacaac caatccttga
    13921 tctgactaag ctcagtaaaa tctgtcttaa cccactctct acctaggtct gtaacggtca
    13981 tctcactggc aatatttcct gccctatgac ctcccatacc atctgctagg ataacaaggg
    14041 taatgccttt tttattatca aatttgttga taaaatcttg attgtttgag cgcttttgcc
    14101 caatatcggt ttttaatgaa atcttcatat aatcttttct gactaggtca gtctcctcct
    14161 aaatactaca agactcgtct gacttgccca ataaagaagc catcagtctg gtattgctct
    14221 ggtgtaatca taagacaacc gtccttgaca atatctgctt gtgcatgctt gagtgttact
    14281 tgttcaaaat taggatgacg ttgtaaaaat ttgtcaataa cttggaaatt ctcttcatca
    14341 aaaatcgtac aagtgctata ggttattata ccaccttttc gcagcgtttg acaaacgcta
    14401 gacaatatct ccagctgaat ttcctgcaat tgctggaagt cctgcccttc cttgttgtat
    14461 ttaatatctg gcttacgcct gatgaggcct ataccagagc agggagcatc aactaaaatc
    14521 ttatcaaagc tgttcttcgc aaaatgctta tgaacctctc tagcatcaag caccttagtt
    14581 tcaatccgat ctgctacccc tagacgctta gcattttcat tcactaaggc cagcttgtgc
    14641 tcatacaaat caagggccac tactttgccg ctcgtcaaat aagaggcaat gtgagctgtt
    14701 ttccctccgg gtgcactaca agcatctaaa atcatttcct gcccttgaat atccagcgtc
    14761 ggggcaacta gctgactggt ctcatcttgg atcgtaatgt ccccattgat gaaataactg
    14821 ctggcagcaa aattgccagc tctcttggtc agaccagtcc tagcaagtaa tgattgctct
    14881 gatcctgttg cctgcttgat ctcatcaagc tttgtcagat ctgtgacacg tatgctggct
    14941 ctgcttctca caaaaagact ttccatgatt gctacagctc gctcctcgcc aaattggtcg
    15001 atcaattttt tgactagcca gaccggtact gagtaagcaa cagcatagta tttgtttttt
    15061 cgcttgatgc tcttgatatc tggtaagggc ttattggtca gctggcgcaa aacggcattg
    15121 accagcttat ctgctcctct gccatgagct ctcgccttgg caagattaac agcgtcatta
    15181 acaatagcat gagcaggcac cttgtctagg taagccagct ggtaaaggct aagcatcaag
    15241 agataataaa cccatttatc cagcctgtct cggtcctcaa tatagtgagc cagataccat
    15301 tctagggtta tcttcctaga gatagtcccg taaacaatct ctgtgactag agccttgtcc
    15361 ttatcactta aaaactgatt cgccagctgg tgcttcaagg caaggttaga ataggctcca
    15421 tgatcaaaaa tatcctcaac gataagcagc gcctgtcctc tagctgattt tttccaatca
    15481 ttcgccaagg acatcaccca cctctaggct tctgccaata ccatttaaaa agtcaacaat
    15541 aggcatcttt ggcttgcctg ctggttgaac gagcgtcaag gatagagccc cctcacctgc
    15601 tgctacgacc aatgcttttt tagttttagc gatgatttgc ccagcagatc cagagccttc
    15661 agccaattca gcctcataaa ttttgaagcg ctgcccatct aataaggtat gagccaccgg
    15721 ccaagggttc attcctctga tatgattaaa cacctctctt gctggctttg accagtccag
    15781 tctttcttct tctgctgaaa gattgggaga aaaggtggct tggctatggt cttgaggaac
    15841 tggctttagg tcaccagaca agtaatcagg caaggttttc aataataaat ctcgtcctag
    15901 aatggccagc ttatcaaaca tggtaccaac attatcagta tctaaaattg gaaggcttgc
    15961 gcttgatatc atatccccag cgtccatctc cttaaccatc tccataatgg taactccagc
    16021 ttccttgtca ccattgataa tagcataatg gatcggagcg ccaccacgat atttaggaag
    16081 taaggacgcg tgcacattaa cagcaaatgt caccgaatcc aataagactg ttggtaaaaa
    16141 ttgcccaaag gctgccgtta caatcccgtc tgctcctaat gccatgatat ctgctagctc
    16201 ctgtgaacca gatagcttct caggctgaaa aacaggcagc tgatgtgcaa gcgccagctt
    16261 tttaacaggc gtcattgtga tgtctttttt gcgaccaacc gcacgatcag gctgggtcac
    16321 gaccgctaaa atgtcatagg ctggtttttc tagtaagccc tgcaaaacag ttgctgaaaa
    16381 ttggggagtg cccataaaaa ttaatcttgt catctatgtc ctctattttc tttctttttc
    16441 attatagcat agcttggcgc aaagtccggt aaagaacact tacataaagc tctgtggctc
    16501 ctgatcaatg ataaccttta gctcgcgatt atcctgctct tggctccaat caagaatttg
    16561 attcagggta gcttcaagct gatcctcaaa gcgatacttc aaaataatct gataatggta
    16621 aagattgtgc gttcttgcaa ttggctttgg cgttggccct aatattctga tctgatcaga
    16681 caagccctgc ttcaatatgg tcagcagttg ataggccttt ttgaccacct cttgctcact
    16741 cttatgcgat agggtcagac ctactgtgaa ataataggga ggatagccta gctttcgtcg
    16801 aatccccatt tcataagcgt aaaaggcttc aaaatcctgc tttttggcca gttgaatcgc
    16861 gtaatgctca ggattgtagg tctgaatcag gacttcacct ggcttgtctg cacgtcctgc
    16921 acgtcctgca acctgagtca gcaattgaaa ggttcgctcc gatgccctaa aatcaggtaa
    16981 atgcaaggaa gtatctgcat ttaaaacacc tactagggtg acgttgggaa aatccaaccc
    17041 ctttgcaatc atttgtgtcc caagcagcac atcagcatca ccatttccaa actggcttaa
    17101 aatagcctca tggcttcctt ttttacgtgt cgtgtctacg tccattcgta atattctagc
    17161 ttccggcaac acttgcttga gctcatcata ggctttttgc gtccctgttc cataatagcg
    17221 tatgcttttg ccttgacagc tagggcatag cttcggaata gccctttgaa agccgcaata
    17281 gtgacaattc atggttttcg tatccatgtg gagggttaag gaaatatcac aatttggaca
    17341 ttgatcaaca tagccacaat ctcgacacat gataaagcta gagtagccac gcctgttgag
    17401 catcaaaaca gcctgctctt ttctagcaag acgctctttg agtttatcaa tcaaataagg
    17461 ggtgaagctg ctaacctcct gctgaccaat ataatctcga aaatcaacaa tctcaacctg
    17521 aggcatactg gcaagaggat tggctctctc agtcagctgg ataaactgat acagtccctt
    17581 gctggctcta gcgcgactat caatactagg ggtcgctgag cccatcacta aggcagcctt
    17641 atggtgcctt gcacgaatga gagctacatc tctggcatgg tatctgggat tagattcctg
    17701 cttgtaggtg gcctcatgct cctcatcaat aataatggct ccaatatttt ctaaaggtga
    17761 aaaaatagca gagcgagcac cgaccaccac tctagcctgc cctgtcttaa ttttctgcca
    17821 ttcgtcaaat ttttctccat ctgacaaacc tgaatgcata atagcgacct gtcttccaaa
    17881 gcgggaaata aatcgagagg tcatttgagg cgtgagggag atttctggca ctaagacaat
    17941 agctgtcttt ccttgctcaa gcacatgcgc aatcacatga agatagacct ctgtcttgcc
    18001 agagcctgta ataccttcca gtaaaaaggg cttagcctct ctgccaacag ccttcgtaat
    18061 ctggtcaaca gcttgctgct gctgctgatt aagctttaag agtggggctg ccttgatgtg
    18121 attgaaataa tcctcactgc gattgacacg tcgctcctca agctcgatca gctggttggt
    18181 cacaaaatag ctaacaacct ctctagaata atcctgataa agcttggcta gcttatcttt
    18241 ttgtggattg gctaacaaat aagcctttaa ggcttggcgc tttttagccc gatttgaaat
    18301 cttatgctcc tgtaaggcta atctattgac ctgatagtaa gtctcggttt tgattgtctt
    18361 tttgtccttg gctagataag ttgccctaat cttaccagac tgtatcagcc taaggacacg
    18421 tccctcctgc tctggactta gcttagaata aagcaaggaa tccccattag agaaaacatc
    18481 agcaaggtca gccgcagcta agtcagctgt cggggtgagc agccgatcgt aatgagaatt
    18541 aagtaggcta ggaagcattg cctttaagag ggtgattttg taggaaaaga ctgtttgtcg
    18601 taattgctct gctaatgcca cctgctcctg atttaaaaca ggctcagcat ctaaaactga
    18661 ccaaatagcc ttcaattgct gcgttgattg actagaaaag ccaataacaa agccctgtag
    18721 caacctattg ccattaccaa aaggcacatg aacgcgagaa ccaatcttaa ccagagataa
    18781 tagctcatct ggaataagat aagaaaaggg cttatcggtt tgcatcaagg gaatatcaac
    18841 aatgacctgt gctatgtgtt gcattttgac ttcctttcta tcaagaaatg gacctgcaat
    18901 atgaaaaaaa ctaagattga ctcaacctta gattttttct ccctcttctt ctttttcttt
    18961 tgcaatctgc tcttttattt tacgctcttc ttcttctctt gctaaacgct ctgcctcaat
    19021 ccttgcacga acagccgcac gcttagcagc aggatccggg tgaatcacaa cattgcctga
    19081 ctcaatctcc tctagtgcct gaagtgttga tttgacagac ttaaaggact gtgtcggtgc
    19141 agcacctgct tctaattcat gagcacgctt ggcctgtaaa ataacaagtg aatattttga
    19201 tgggacttta tctaataaag tatcaattga aggttttaac atcatgggct ttactctttt
    19261 ctatttctat catctgagag attttgttgt tttaatcatt tgatcatagc gaccaatcac
    19321 acgctcaacg cgaaaatgct cggtctcaat aatacgcttg acacgctctg cagctaaagg
    19381 aacctcgtcg ttgaccacag cataatcata ctctcgcatg agcgcaatct cttccttagc
    19441 tctttcgata cgcttggcaa tcacctcttg gctgtctgtt ccacgaccaa ccaaacggtc
    19501 ctgcaattca tctaagtctg gcggcgttag aaaaatgaag acaccatcag gcaccttagc
    19561 cttgacctgc aaagcaccct gtacctcaat ttccaaaaag acatcaatgc ccttatcaag
    19621 ggtttcgtta acataggtta agggagtgcc atagtaattg ccgacatact ctgcatattc
    19681 tagcatttga ccatttttta ttagctcttc aaattcttct cgtgtgcgga agaaataatc
    19741 aaccccatca acttcacctg gtctctgtgg acgtgtcgtc atcgaaacag aatattcaaa
    19801 tttatgatct ggcgttgaaa aaatctcttg tctcaccgtt ccctttccga cacctgaggg
    19861 gccagagaaa acgattaaca aaccgcgttc agacattgtg ttctccttat tgattgcttt
    19921 ctaatagttt atcaaaaagg ctatcgtttt tcaagacaat tatcagccca atcctaagaa
    19981 agaaaaggaa gagatagacg ccttctcaaa gctagaggct aaactctggc ttttgaaaag
    20041 catacactct ttccttttta tttcgcataa tctattgctc gcaactcacg aataacagtt
    20101 accttgatat ttcctgggta atccaagtta ttttcaatct tttctcttac cttgtgtgag
    20161 agaaccacaa tctcgtcatc agaaatcttt tctggctgaa ccatgatgcg aatctcacga
    20221 ccggcttgga gggcaaagct actttgaaca ccatcaaagc ttgttgcgat ttcttcaagg
    20281 tcacgaagac gcttgatata gttttccaca gattcattgc gggcacctgg acgagcagag
    20341 ctaagggcat cagcagcagc taccagaact gcaataaccg aatccggctc gacatcgcca
    20401 tgatggctgg ctatggtgtt cacaacaaca gggtgctcct tgtacttgcg agcaaactcc
    20461 ataccaatct caacgtggct tccttcaacc tcacgatcaa tagccttgcc catatcatgc
    20521 aagaaacctg cgcgacgtgc aagtgccaca ttttcaccaa gctcgccagc taaaatacca
    20581 gctagcttac caacctcgac tgagtggcgt aaaacatttt gaccaaatga ggtacgaaac
    20641 tgtaagcgcc ccatgatctt aatcaaatcc gggtggaggt taggtgcacc gatctcatag
    20701 gcagcagcct caccatactc acgaatccta ttgtccatct caagacgatt tttctcaacc
    20761 aattcctcga tacgcgccgg gtgaatacga ccatcagcaa tcaaggactc tagggtcata
    20821 cgagcaatct ctcgacgaat agggtcaaag cctgataaaa caaccacttc cggggtatcg
    20881 tcaatgatca catcaatccc tgtcagactc tctagagtac ggatattgcg accctctcga
    20941 ccgataatac gccctttcat gttatcatca ggcaagtgca cacttgtaat cgtctgctca
    21001 gtcacatact caccagccat acgttgcatg gcctgtgcta acaggtcctt agcagtcttg
    21061 tctgtcctgt ccttgatgtc acgctctgca tcacgaatgc gtgttgcgat ctcatgcgtc
    21121 agcttgtttt cagtttccat caggataacc tcacgcgctt ctgcaatggt catagcagca
    21181 actcgttgga gctctgctct tttgtcttcc tcaagttttt caacctgtgc ctgtcgctca
    21241 tcaatgtgct tagatttatc ggtcagactt tgctctttgc tatctagtac tttttcttta
    21301 cttgatagat tttcatcctt acgatcaaga gttagagcac gctctgccaa gcgcgtctcc
    21361 agctgtttaa gctcttgtct ttcagattta aattcctgtt caatttcttc acgatacttt
    21421 cttgcctctt cctttgcttc taaaagtaat tctttacgac ttgctttact ttcacgttgt
    21481 gctgtctttt tgatatgagc ggcatcggcc tttgccttgc cacgaatatc aacagcatcc
    21541 tgttcagcgt ttaaaagagt caactctgca gcttccttcg cagacttgag tctaatcgaa
    21601 ataagtgcat aacctaatat tacaccaatg aggccacaga caagtaacgt tatgatatta
    21661 attaacatgt ctttacctca ataatagttt agttttcatt aacagaaagc catctcttag
    21721 tctatcataa aatgaagatt tagacaattt aaaatccacc tacatttttc taaaatctag
    21781 tgattttatg ttatgatatt gataaaaata aaaaggagtt tcttatgcca aaagaagtta
    21841 ttgttgaaag ctttgagctt gatcatacta ttgttaaggc accctatgta cggctaatct
    21901 ccgaggaatt tgggccccag ggagatgtga ttacaaattt tgatgttcga cttgttcagc
    21961 ctaatcaggc tgccattgag actgccggtt tacataccat tgagcattta ttagccaagc
    22021 tcattcgtca acgcattgat ggaatgattg attgctcccc ctttggctgc cgcacaggct
    22081 ttcacctcat catgtggggc aagcatagct caacagatat tgctaagatc atcacgtcca
    22141 gcctagagga aattgctaca agcatcactt gggaggacgt tcctggcaca accattgaat
    22201 cctgcggcaa ttataaggat cacagccttt ttgctgctaa ggaatgggca cagcttattc
    22261 tcaagcaagg gatctctgat gatccattta accgccatgt cacctcataa aacgaaagcc
    22321 tctcttttct gctaatgtga aggaggcttt taatgtattc aaaaaggtgc caaaggcaag
    22381 gctcaatgcc cttaccttta gcacctgtga taactagagt atccagttca ggatcacacc
    22441 ttgtcttcta agcattaata gtctaagtcc tctgcatgcc ccttgccatt tccgacaaaa
    22501 tagcctgttt tgcaattcaa tgaaaagagg taggtgccat caggcttaaa catgttgtaa
    22561 tagccattcc cattgataat attgaccggc tctaggatat aatcattgcc tgaaatatag
    22621 ccccttgctt gtgaggtagc cacaatacgc tcaagcacac ctggattaaa ggcccaagca
    22681 gggtttcctg tatcagcaat catagcctga ttgtagggca cacgagacag gtcacgctgc
    22741 aatattgaag ggtcatagcc tgtaatgcca tacattggag ccactggagc tggtacagca
    22801 ggaacctccg gagctgcagg gcttgctggt aaggcagaag cagctggagt gctagctgct
    22861 tgggtagcag acctgcttgc tagctgctca cgacctgcct tgatgcttga ttgtagcaat
    22921 gaatcaagtt ttgcattacc agtggttagc gtatcactag ctaggtcatc aaaattagca
    22981 tcagctttga cctcagctgc aatcttttca ccattgacaa ttgcagctgt tgtaaatttc
    23041 ccattaaccg cctgaatagc tgttacttgc tttttcagcc cagtaacctt ttccttagcc
    23101 ttgtcataat aggctgtccc ttcaagcctt tttaaagcag tctccaaatt cggtaactga
    23161 tcaaaggcgc tattttttag ggttgtttta tcattatctg tgaaaaatgt cttgtaaaga
    23221 tcttcaaaag ccttagcatt agcctttgtt ttgttggtct gattagctgt tgatgctttg
    23281 ctccttgctt ttttagaaac agtagccttt gactgaggct tatgcttaga cagctgatag
    23341 atatggttga gggcaaaggc tgaggctaca agggttagcg tggctaacaa aatagcaaac
    23401 agaggctttt tctttttaga cctacgacta gcatagctat ctgataaaat actctctact
    23461 tctgcaggtc gctcgctaac tgcgtcatca gctagctgcc cagtaaaatc actagcagaa
    23521 tcagtagctg ccgctgaagt gtcagctcta gctgctagag gctcaatgaa tgaggtctca
    23581 ccggctggct tctcctctgt tgaagcctcg tccactggct caacatcaac taagccggct
    23641 ttgctgagct cctctctttg ttttttgata aagttatcca gacttgctgt atctaactcc
    23701 atatactttg catcaaactt ttgtgatgac acttcgttac gatgccgctt aatatatttg
    23761 tctaaaacac tatcatcctc ggtaatccct gcttttagct ctgagtcctt gcgtactgcc
    23821 tcaccgattg tcattttttt ggcttcatga agctccaaat tttggctttc tgcctctgat
    23881 tcaaatgctt tgcttttttc tgacacgttt tttacctctc tatatcagat tgcgctttac
    23941 cctctctcca taaaattgat acaaatcaac ccttagagta ccattataaa gcttacgttt
    24001 tttatcagct ttttgaccat atttttgttc aaaatgatca tcactcgtca aaataaactt
    24061 gctccaggta actaatggag caaagacctg taccatctca ttatacaaga tgtctactgc
    24121 tttgtcatca agcaaacgct ctccataagg aggatttgaa atgatgacac cgtttatctt
    24181 gtctgtacgg aaatcctgca agcgcatttg cttaaaggta atgatatcag ccaagccagc
    24241 ctcctcagca tttctcttgg caagctcaac catacgaccg tcaatatcaa agcctgaaat
    24301 atccagctca atatcataat tagcctcttt ttcagcagcg tcacgaacct tttgaacacg
    24361 atctttgtcc acccagctcc attcctcaaa ggcaaaggag cgattaaagc caggagcgat
    24421 attcattccg atgagagccg cctcgataca aaaggtcccc gatccacagg tgggatcaac
    24481 caagggctta tccggaaacc aattagacag cttgaggata gctgctgcca tgttttcctt
    24541 aataggagct cccccttttt ccacccggta gccacgctta aataggcttg agccactagt
    24601 atcaatcatc agggtagcct gatcctttaa gattgagacc tcaattttga actcagcccc
    24661 cacctcttga aggggaatat gctccggtct atgaaaatgc tgctgcaatt ttctgacaat
    24721 ggcttttttg gtaatggctt gaacacttgg ctcgttgtgc agggttgacc tgacacactt
    24781 agcctttgca ataggaaacc tagcacctaa gggcaaataa tgctcccaat ccaaggcaaa
    24841 tacgccctga aacagctcct caaagcttcg tgctgggaac tgacctacaa taatcttaat
    24901 acggtcagcc gctcgcagcc aaagatttgc tttagcaata gcttcaatat cgccttcaaa
    24961 gaagaccttg ccattatcta ctcggcagtc aaatcccaag gcccttaatt ccttacccac
    25021 aacagcctct aggccagctg ctgcagttgc tactaatgta aattgttctt tcatatgact
    25081 ctttctatcc taaccaaata aaagctagca tatgctagct taacctatta tgcaattttc
    25141 tataagccat gttttgttcc agaaataact aggtattatc tccttcgata atcatctgtc
    25201 tactgtttgt caacagtcag gatagcttgt tcgtttccaa ctatcccatg cccctaccaa
    25261 agtttgggtt gctagcttga ggggtttacc gcgttccact ttttacgttt ccataaaaac
    25321 ttcgtcactg tggcactttc agagctactc tggcatatca aggacttagc cttttcactc
    25381 gccgtaatgt gtcaaacaca tccctaggct tatttgttcg cctagcacaa acactaccag
    25441 catcacagcc ggtgctagca tggactttcc tcatagtatt gcaatactac gcgattatcc
    25501 aaaaattgca catctacatt actcaataat ttgctttcca aaaacctctt tttccagctt
    25561 gctaatgcgc tttagcatgt caaaattggt ggctgactgt gctactctgg ttggctgtga
    25621 taccgcctga gagctgcctg ctaaaggatc acgcacctga gccttagcct tttttaaggc
    25681 ttcattttca gcctttaggg cctcgatctg agcattgaaa tactcataat ccttgatgac
    25741 gttatcaagg aattcgtcga cctccttctt atcaaagcca cgcatactgg tcttaaattc
    25801 ttgctcaaaa atgtcctttg gactataaat tatacctgtc attctatact ctccaaacgg
    25861 tcaatctttt tcaaatatca aactttgata tcactactta tggtacagaa aaataaatta
    25921 aaaagcaagt atttaaatac cagtgatttt taaatatcac tagctactca tctgcaatgt
    25981 catttaaacg ctcaaagttt aggaaagaaa gggggtaaca gggctgctcc ttcatagctg
    26041 ctaccaaata gcttaggcgc gtttcgtgct cactatcata aaaaagatag gctccgtctg
    26101 tattgtgaat caaaaagtga tggtagctct ttagctgttt agggctttca tagctgggat
    26161 agctatattt gacaaaatca gtctcccgaa attgctgcag ctgctgctga ttgcgatcat
    26221 tccaagtgct gccatgcgtt tcaaaggcaa aaatagtcgc tgtctttaag gggtaggtct
    26281 ttttgaggtc attagctacc tctaaagccc actgctcaaa ccctaaattc ccagtaaaaa
    26341 taaaccagtc taccccctcc tcaagataag caatcagatc tctttctatc gcttttttga
    26401 taatggcaac tcttttatcc ttttcactaa agatgcccag ctcaaaactt cgatagcctg
    26461 ttacgagaat tgcagtcatt agatgttatc ctttcaaaaa tatgttataa tgtgaatgct
    26521 taaattatta ttaagtcatg atgttaggag aacaatggtt aactaccctc ataatcctat
    26581 tcgccaaaag gtgacccctc ttcaaaagca gcaaaagcac aagcaagtag actttgctaa
    26641 tcgtggtatg tcctttgaag catccattaa tgcaaccaac gcttattact tggccaaggg
    26701 cattgctgtc attcataaaa agccaactcc gatacagatt gtcaaggtag actatccaag
    26761 acgtagtcga gccaagattg ttgaggctta ttttaagcag gcttcaacga ccgactattc
    26821 tggtatctac aaagggcatt atattgattt tgaagctaag gaaacaagac aaaaaacagc
    26881 tatgccaatg aaaaactttc acgcgcatca gattgagcac atggctgctg ttttaaagca
    26941 aaaaggcatt tgctttgtcc tccttcactt tgcgacacta aaggaaacct attatctacc
    27001 tgccaaagca ctcattgatt tttatcagat tgataggggc aacaaatcaa tgccacttga
    27061 ttatatcaga aaaaacggct ttgaggtcaa gctgggagca tttccacagg ttccttattt
    27121 agatattata gaacaaaaat ttttaggcgg tgattacaat taacaatcca aaaatcctta
    27181 aattcctgaa gtatacatta ggtgctatcc ttagccttat cattgtgaca attaccttag
    27241 gtggcctttt gtttgcttac tatatcagca gtgcccctaa gctttctgag gcccagctca
    27301 aatcgaccaa ttccagtctt gtttatgacg gtaataatca tttgattgct gacttgggct
    27361 ctgaaaagcg tgaaaatgtt acagctgaca gcattcctat taatctggtc aatgctatta
    27421 tttctataga agacaaacgc ttttttaatc atcggggggt tgatctctat cgtatcttag
    27481 gtgcagcctt tcacaattta acaagcaaaa caacccaagg ggggtctaca cttgatcagc
    27541 agctgattaa gctagcctac ttctcgacaa acgagtctga ccagaccttg aagcgaaaag
    27601 ctcaggaggt ttggctggcc cttcaaatgg agcgaaaata taccaagcaa gaaatcctga
    27661 ccttctacat caacaaggtt tatatgggaa atggtaatta tggtatgctg acagcagcca
    27721 aggcttatta tggcaaggat ttgaaagatt tgtcctatgc tcagctagcc ttgctggcag
    27781 ggattccaca ggccccaagc cagtatgacc cctacacaca gcctgagaca gctcaaagcc
    27841 gccgaaatat tgtccttcag caaatgtatg ctgaaaagaa cattaccaag gctgagtacg
    27901 aagcagctat cgccacacct atatcagaag gcctacagcc tctccagcaa cgcgccagct
    27961 atccaaaata tatggataat tacttaaaac aggtgatcga gcaggtaaag gctgagacca
    28021 acaaggatat ctttacctct ggtctaaagg tttacacaaa catcattcca gaggctcaaa
    28081 aaaaacttta tgacatttac aattctgagg actatgtgta ttaccctgat gctgactttc
    28141 aggttgcctc aaccgttatt gatgtcacaa atggacacgt tatcgcccaa ttaggaggac
    28201 gcaatcagga taccaacgtt tcctttggaa ccaatcaggc tgtcttaacc gatcgtgact
    28261 ggggatccac catgaagccg atcacagact atggacctgc cattgagtcc ggtgcttaca
    28321 attctacagc tcaaacaact aacgactctg tctactattg gccggggaca cacactcagc
    28381 tctataactg ggaccggaga tactatggtt ggatgaccat tcaagctgct ctcatgcaat
    28441 cacgaaacgt ccctgcagtt agggctctag aggcggcagg tcttagctat gcacagtcct
    28501 tcctcagtga tctaggcatt aattatccag agatgcatta ttcaaacgcc atctcaagta
    28561 acaatagcag ttctgattca aaatacggtg caagcagtga aaaaatggct gctgcctatg
    28621 cagcttttgc caacggtgga ctctattaca agccacaata cgtcaataaa attgaattca
    28681 gcgatgggac cagcaaggtc atcgaaaata agggcaagcg tgccatgaaa gaaacaacag
    28741 cctatatgat gactgatatg ctaaaaacgg tactaaccta cggtacaggt actgctgctg
    28801 ctatcccagg agttgcacag gctggtaaaa ctggtacctc aaactatacc gatgaggagc
    28861 tggcacaaat tgttgagaca catggactat ctcctgatta cgtgggaaca atggcgccag
    28921 atgaaaactt tgtcggctac accaaccgat acgctatggc ggtttggact ggttataaaa
    28981 accgtatgac gccaatttat ggctacagcc tagaaattgc ttctcatgtt tatcgcaaca
    29041 tgatcagcta tctcaccggc ggctacagcg acgattggac catgccaagt gggctctatc
    29101 gtagcggcgg cttcctctac ctaagtggta cctatacaaa cagtagcgat tatacaagct
    29161 ctgtctacaa caacctctat ggtaataaca gctcagcttc aagccaatcc tcagatgagg
    29221 atacaactga agacagccac tcagaagcaa acgacagcac aacgtcatca tcagagcagc
    29281 aatcaagctc caccgatgat aagaaaacca actgataaca aaaaactggt tcaaatgttc
    29341 tgaaccagtt ttttcaatta tttggctaag gcacccatcg gatcccaagg ggcaagtacc
    29401 tgtggttctg cctcataggc tgctaattca tcagctgtta gtaggtcctt gcgaacaaca
    29461 atctggtaag tatactcgtc catccaagca tcagaagcaa caaagtatcc tttgtcacca
    29521 accttgtctc cccaagaatt ttcaaccttc catttgatag gcttaccagt atcatctaaa
    29581 tcaacacctg tcaaaaccat agcatgtgtc attaagcttt cgctgtaatc aaggcgacca
    29641 gccttgtctt ggctcaactg aatatccata cctgcctgaa aatcataggt attaagggct
    29701 agaatcccct tttgacgatc tgatacctga ccaacgtctg aaccaaacca aacggactct
    29761 ccagcctgca tttgcttaat agcaagctcc ttgaagcgct ccatatcaag attaaggtag
    29821 cgcacctcag gactgccaac aacattacca agcatatcaa ccgtataaga tttgccataa
    29881 ggcttatcag ctgttggggc gttgataaca gacacataat cagacagctt tagaccaaca
    29941 tatttttcat aaaatgcctg tggtgtgatg cccttatcag catgatagtg attatcctta
    30001 tcacgataag caaaatcaaa ttgacgaggt ggcaaaccaa gattcatggc taagaaatta
    30061 aagatttcct gaagtagctc ttctttttta gcctgtactg cctgatgatc agcaccagca
    30121 ctgatcacat ctcgaagaat ctgagcgtcc tgacgcaaga gcttattgag gtattgattt
    30181 agctcacgac tattgcttga tgacacagac tctgggtaga ctgattttgg cacaacaccg
    30241 tatttttcaa acagggctac aaccatgtcc cactgaccac cgtcttgctg cggaacgtcc
    30301 aaaagaaact taaccctacg gctagtcaag gcttgatcag cagttgcaat cacctgttcc
    30361 ataaaccagt ttgatttttc gtatttgtcc cagaaaaagg tgtgtgcttg tgacaactca
    30421 aaatcttcta atttaaattc tgaaataagc ttatggcgaa aggtgtttaa ggctgcaaac
    30481 atccagcaac gacctgaagc cttttgatta gagaccttat cctttgtcaa gtcaatggaa
    30541 aagacaaaat cattgtcgat ctcactttgt cttgtctcca aggatttaag caagccattg
    30601 tgagtgatgg cattttcaag agctaaatat ttagcattag cttcataatt agcatatagc
    30661 tgttctgtaa atgtctctgt taatactgac atcattttcc tccaaagata ataaataaca
    30721 acacctaaaa ataaagttga cagaaaaatc cataaatact gtcaatttca ttttcaagga
    30781 ttacttctat tatagacctt atttgatatt cttcaagtaa aaaaattagg ctaacttaat
    30841 tttttaaagc taagcagcag ctttccaata accagacaaa aagccatctc aaaagacgac
    30901 aaaacctgct ggactttgag cacctaaaca tgtcatatgt ccacctcagc atgaactcaa
    30961 agaagctagc tgtgtctggc tatgacttca gtttaatcat tagcttgcct tagccacaaa
    31021 aagaatcgtc tccactgtag caaaagtgct tgatataaca ccatcggcta agtcaagggg
    31081 cccctgatag ttaactgaaa catatggcaa agctaaaacc aaagacttct tctccttaaa
    31141 gcctctggtt tttagttagc tgagcattct cctttatctt ggctgcttta agatagggac
    31201 aaatcaacaa ctaccccaat cccatttaca aaaaagccct aagtcagagc cttcataggg
    31261 ctaagggtga gggaagctct taggcaacag ctactggatt tatgcctaat agaagctcct
    31321 gtccctcctc acctatttaa aatagcattg gtttatctat agcctgtgta ggtttgagga
    31381 tcacttccaa aagtcatcaa aaatagtaat tggcagatgg cgcttgtgct gccctttatg
    31441 ccaccagtct tcaatccttg cctgagcttc agcggaaatc gtatgcccct ctaagtaatc
    31501 gtctatctct tgataagtaa cacctaatgc tacctcatct gcaagtcctg gcttcttatc
    31561 ctctagatct gctgttggca ccttctcata gaggctgggg tcagccttta gcacctttaa
    31621 caaggcctta ccctgccgct tagtcaagcg aaaaaggggt agaatatccg ctccgccatc
    31681 accaaactta gtgaaaaagc ccgtaacatt ttcggcggca tgatctgtcc caatgacagc
    31741 accagctgtt tgaccagcga tagcatactg actaatcata cgctgacgtg ccttaatgtt
    31801 tcccttatta aagtcagaaa tctcaagccc tgccgcctct aaggctctta gctgaccatc
    31861 aacagcctct ttaatattaa ccgtcaaggc ttgatcaggt tgaataaatg ctaaggcttt
    31921 ttgtgcatct gcctcatctg cctgaacacc atagggcaag cggacagcga taaattggta
    31981 ctgctcatca cctgtttcag cgcgcagctc ttcaatcgcc atctgagcta gctttccggc
    32041 taagctggaa tcctgaccac cagaaatccc taagacataa gtctttaaaa aagggtgctt
    32101 taacaaataa gcctttaaaa aatcaaccga ctggcgaatc tcctgcttag gatcaattac
    32161 tgctttgacc tcaagctgac gaatgatatc ctcttgtaat gtcatatcaa atcactcctt
    32221 ttacaggctt ccttgcggat tttgtcaata agatgcatct tattttgcca aacatcaagc
    32281 gcaagatcca cagggtaatg ctgcggattc aagacacgct tatattcgtc ccaaagctta
    32341 tcaaattcct ttctagcata agccttgatg tcttttaagc ttggcagctg ataaacgagc
    32401 tttcctttat caaaaatatc tactagcaaa ggaacagcat caaaatctct gacggtttta
    32461 ttaatgtagg tataagtcgg gtggaacatg tgaatttcct ctaggtcatt gacattaaca
    32521 cctgtaaagg tgatgtaatc gccttctgac ttgccctttt cgcggctggt aattcgccaa
    32581 acctgctttt tacctggtgt tgataccttt tctgcattat ttgatagctt gatagtatcg
    32641 cgcatggtac catctgcctg ctctatcgaa acaatcttat aaaccgctcc cagagctggt
    32701 tgatcatagg ctgtaatcaa ttttgttcca acaccccaaa cgtcaatttt agctttttgc
    32761 attttcaggt tgagaattgt attttcatct aaatcattgg aagcgtaaat cttagcctct
    32821 gtgaagccgg cagcatccag ctgctggcgt acccttttag ataggtaagc aaggtcacca
    32881 gaatccagac gaacacccaa gaaattaatc ttatcaccta attccttggc cacacgaata
    32941 gctgttggga cacctaccct caaggtatca taggtatcaa ccaagaaaat acaatccttg
    33001 tgcacactgg cataggcctt gaaagcatca taatcattac cataggcctg taccagagca
    33061 tgtgcatgcg tgccagacac aggaatgtca aaacgctttc cggcacgaac gttactagtt
    33121 gcgtctgctc cgccaataat ggcagcacgt gtcccccaaa cagcagcgtc catctcctga
    33181 gcgcggcgtg tcccaaactc taaaagtggc tcatcttcaa taacagagcg aatacgagct
    33241 gcctttgtag caatcaaggt ttggaaattc acgatattca aaagagctgt ttctactagc
    33301 tgacattgac ctaaaggtcc ctcaacctga acaataggct cattggcaaa gaccaagtct
    33361 ccctcttgtg ctgagcgaat cgttagctct aaacgaagct ctctgagata ggtcaaaaaa
    33421 gcagggctgt agcctagctc cttcaaataa gccaaatcgg tctcagaaaa ggtcaattgc
    33481 tcaaggtatt ctacgattcg ttgtagacca gcaaaaactg catagccatt gttaaaaggc
    33541 tctctacgaa aataaacctc aaagacagca ttacgattat gaatgccctg ctcaaaataa
    33601 acctgcatca tatttaattg atataaatca gtatgaaggg ttaagctatc atctctgtac
    33661 atataagtaa ctccttaaca taattgttat tattatacca tatttttggc atagacctgt
    33721 aagattcaac taaaatcctc tgctcaagct ttctaaaaaa gaagccttga gctgctatta
    33781 agcctgacat attttttgcc agtaccttcc taaaaagtct atagcacaag ggcttatggc
    33841 tttttaacaa aagcagtttc agttgatagc attcataaaa aaagattgaa gaaattgacc
    33901 aaaatagccc ctttcttcaa tctatttaac tcacacctta gccttttaac gcttttttac
    33961 acttgagctg actgtagcag ccaaagacta gaatccaaat gctagcacca attgccccga
    34021 tataggtgga cttctgtaaa aacagtgaaa taaaaacaaa ggcaaaaaag gctagggtca
    34081 atggtgttgt tagctgataa cttggcatca aataaccatc tggcataaag tcactggact
    34141 gacgatattt ccaatgcgca agcatggtca aagcataaat cgcaatataa acaccagatg
    34201 atgaggccgt aatcagcgaa aaggcatctg caacaccggg caggatatta atcaaggccg
    34261 acaccccaac agcaacagca gaagcaataa tagccctact tggtacccct tgacgagata
    34321 gggtgttaat cctcaaggct ttagtaagag catttggggt ctcattagcg atttgataca
    34381 aatgccgacc tgtcgaatac agggtcgaat ttagggctga tgctgctgat gttaagacca
    34441 caaaattaat taaagcagca gcccatttaa tcccaatcag cttaaagacc atcacaaagg
    34501 gagactcgtc cgtaggcaac tgataccaag gcacaatcgc cataatagac accaaagcac
    34561 caacgtaaaa aatgacaatc cgcatcggaa tctcttggat ggccttgggc aagacctttc
    34621 taggatttgc ggtctctgag gttgtaatac caacaaattc gatggcctga taggcaaaga
    34681 aaaccatctg aaaggccatg aaaaatttca acttcccatt cggaaatagt gaaaaatgat
    34741 ccacaatatt ggcaaggctg gcatgaccga catgcgtttc aaagcccgtt agaaccataa
    34801 aaacggctgt tgcaatcaag gctaaaatcg caacaatctt aatcatggca aaccaaaatt
    34861 cagtctctcc aaagacccgc acagcaatta aattgatgga gctaagcaac accaaaaaaa
    34921 cgagctgaat cagccaagat ggccaagcag gaaaccaaaa ctgaacatag gaggcgacag
    34981 ctgtaatctc tgccatgcca ataaagatca gggaaatcca gtaagaaagc ccagaaaaat
    35041 agccccagcc tggcccaata tattttgtaa tgaaattgat aaaggtatgc tgatccggat
    35101 catagtatag catctcacca atagcccgca tcatcaaaaa cataaagaca cctgtaatca
    35161 tgtaaacaaa gataatagac ggacccgtta aggcaataga acgaccagct cctagaaaga
    35221 gacctgttcc aatagtgcct gctatcgcaa tgagctgaac atgtcggttt tgcagccccc
    35281 ttaccatgcc attctcaagt tctttagtgc ttttagcttc ttttgtagac atttgactct
    35341 ccattcaatt aaaaaaacac cactattata tctgtttttc agaaaatgtt caactttctc
    35401 taaggcttgc aaactaaaaa ggccaaccaa gcctttttag cgttaacctt tttaagatga
    35461 taggctttca atgtaatggt agacgccttg accggcaatg gcaccatctc caactgctgt
    35521 tgtgatctga cgcagctgct tttgacgaac atcaccgaca gcaaaaatac caggaatact
    35581 tgtcttcatt tgatcgtctg tcacaatcca gccctcttga ttggtaatgc ctagctcaga
    35641 taccatttga gtaaccggaa tcaagccgac atagataaag acaccaccaa agtcatggct
    35701 agtcacttga cctgttttga cattttcaat cacaacatta gagaccttaa tatcgtttcc
    35761 ttgaatctcc ttgacaacag aatcccagat aaaatcaagc ttttcgttgg caaaagcacg
    35821 ctcctgcaag atcttttggg cacgcagctg atcacgacga tgcacaatcg ttactttctt
    35881 agcgaactgg gtcaggtaga tggcttcctc aactgctgaa tctcctcctc ctacaactaa
    35941 taactcctga ttgcgaaaga aagcaccatc acagaccgca caataagaaa cacctcgact
    36001 ggtgtactcc tcttctccag caacacctaa aagacgatgc tttgctcctg tcgcgacaat
    36061 cactgtttta gtatcgtagt gcgtatcttc tgtgtacaca cgcttataat caccacaatc
    36121 ctcaaccctt tgaacaatgc cataaatgtt ttcaacctta aatttttcaa gcggctcata
    36181 catctttaac gatagctctg gtcctgaaat gtgatcatag ccaggataat tttcaatatc
    36241 tgatgtgtta ttcatttgac cgccaggtgc cccctgctca ataatgccaa ctcgtaggtt
    36301 actacgtgct gcatataaag cagctgtcat accagcaggt cctgatccaa taatgagtgt
    36361 atcgtacatg ggttaactcc tcttaatagt cttgtcatca ttttaacaat agctacatcg
    36421 tattgcaatt atttcgcctt caataccacc agaatgctca taaaggcaaa ggacaaaatc
    36481 ggaatcgtca aaatagcaac cataatcatc tcatataaaa atgcctgtct ctggagaatg
    36541 gttttatcct ttttggtcac agcacgccat aaaatccaca aaagacaaag catgaccatc
    36601 gtaatagctg ctaacaacag accttccaaa taaaagcgaa aaatttctac taacatcttt
    36661 atctacctga ttaccataac cttttttcat ggcagcttag cttttaagca catacaagaa
    36721 aagcctagcc tacctagacc tttttattat atcaaaagcc ggcttttaaa tatacgtttt
    36781 tgcatagttt gcaaaaaatt cctttgttct tgcttcctta gggtgtctaa agatctgctc
    36841 aggagctccc tcttcaagaa ttttcccctt gtctaaaaaa agcaccctat ctgcaacctg
    36901 ataaacaaaa gccatatcat gactcactaa aatcatcgtt tgacctgcct tggcagcatc
    36961 aataatagac cgttcaacct ctccaaccag ctcaggatcc aaggctgagg taggctcatc
    37021 taataatagc acatctggct tcatggctaa agcacgcgca atagcaaccc tttgcttttg
    37081 accgccagat aaatgacgag ggtaatggtt ttcacgatca gacaagccaa ccttagctaa
    37141 ttctgctcta gctatgtctg ttgcttcttg gtcagacagt tttttaacta tttttaatcc
    37201 ttccttgaca ttgtcaagcg ctgtgcggcg ttcaaagagg ttaaattgct gaaagaccat
    37261 cgctaatttt cgtctaagcg ttagaatgtc ttcttttgtg atgtgttcaa agtcaactgc
    37321 aaagtcatca atcgtaatac ttcctgtatc tggctgttca agataattca tgcttctaag
    37381 gaaggttgat tttcctgcac ctgatgcacc aaccagagct ataacctgcc ctttttcaat
    37441 cgtcaccgtt aaatcgtcta agatcttttg tccagagaag gacttggtta aatgagttac
    37501 cttaatcatt agcgcaattc tcctatcttg ctattatttg ttgggattgg tgctttgata
    37561 gccatgttat attcaattag gcgaccagcc tgttctatca aaatactaat gccccaataa
    37621 actaaggcaa ctgagatgta acgttcaaaa taacgataat ctgctccccc tagaatctgt
    37681 gcctgtgcaa acatttcaac gatacctgca ttgaaggcca gagaggttcc ctttgtcagg
    37741 cctatcaacc cattaatcaa ggtcggtgtt gccacaacag cggcatttgg aatgataact
    37801 cggcgataaa cctgagcaga ggtcattcct aggctcttag cagcctcaat ttcgcctgtg
    37861 tgaacagatt gaatcgcagc tctaatggtt tcactcgtat aagcagcttc attgaaggca
    37921 aaggcggtaa tcgcaaagat agaagccgga atagcgttga tattccaatc aaagccatag
    37981 cgttgattta agaatttcag aaaaagagga ataccatagt agctcagcat tagctgaacc
    38041 aatatggggg ttccacgcaa aaagctaaca aaaaccgctt gaatcggata aagaatgcga
    38101 accctgttga ttttgacaat ggcaaaaacc aaggccaaaa aaagacccaa ggcagcacca
    38161 gctatcgtca aaccaagtgt gattggcaga cgcctgataa tatctggaat ggcatcaaaa
    38221 acagcatgcc agctaaacag cttcccttct gggatcaacg agatgagctt gtcataccaa
    38281 gcccacccac ttgttaaaaa cgtagatgtc atgtatcgcc cctttatact ggtttgtctc
    38341 aatattttca ttttaacatt cttgagatgt catgtaaaat agtaaatccg catgataatg
    38401 ataagaaaag cctatcgcag aggataggac tcaaacaaag gaaaaaaact ctttgaaata
    38461 ccgttaacag tagcctcttg gagctaccaa gcttgaactt gagccgaact ctcaaagcct
    38521 ccaagtggct aattctcaaa gaatatagcc actggtacaa gactaacaat cagctactag
    38581 gccaaaaagg tcaaaagctt ggctagctgg cacagctaac tgcctcaaag gctaggtcaa
    38641 cgaaagattg aagcctgccc agggcttgag ggcttttagc cctgtcaatt aattgacctt
    38701 ggagataaag tctcctccca aaaatgcttg gctgagcttt ctgagctgac ctgatttttt
    38761 aagcttagcc agccttttgt tgacaaagct ctgtagagcc ttaccctttt gatcattggc
    38821 aaacacataa tattccaagc catccttagc agtatcagcc tgctccttga gctttgtcac
    38881 atgcacatca aagccttgct cctcagctac ggttgttaga gaaatagcgt catagaaaag
    38941 aaagtccagt tgaccattct ccagcagctg cagcctttga gtaaatgggg ttgactcaga
    39001 agcataggta aggtgaatag gcttttggtc aggatgggat tggttccatt tttcaaggat
    39061 aagcatgtaa ttggagccag ctattccttg ggttttcttt ccagaaagat cagctaagct
    39121 tttatactgc tgcttaccct ttgttgccag agcataatgc gaggccgaaa tagggcttga
    39181 aaacaaatac ttttcagctc tttccttact atagccaaaa ttattggccc caatctgata
    39241 acgacctgca tcaataccag ccaggatcga tggaaaagga accacctcta tgcttaaccg
    39301 atactttttg gagcctttaa aaaccctttt tagaacctca atatcatagc ctgtaacgct
    39361 atgcttcttc ctataggtaa agggcttagt ggcagcatct gttgctactc tgatcacctc
    39421 tttttgacga gctgtgacct catggctagt cacgactgcc aagagtccta gacttgctag
    39481 caaaaaaaag agtgctcgct gtaattgttt tgtcatacca tactcctatc tcttatacag
    39541 tagccatttt aacaaaaaat gataaatttg aataatatca tttctctatc aaggcaataa
    39601 gaaaatagta tcaaacaagc aattaaaaca gcacattctt catttacctg atcatggatt
    39661 aaccacaaca gacaagcttt agctattagc aggctgccta agccaaaatc aacacctcaa
    39721 gctttcaact gactgatgta aaagctagta gtcacctcta caagaagaaa aagaactgtt
    39781 tgtgtcattc aaccagtagc acccttctta actggtcatt cctatccagc tctactacta
    39841 ggctgtcagt taacgatcag aaaaaaagtt gacctatctg ccttatgaag cctagaaaac
    39901 tagctttcat tctgtttaac attagaaaac gagtaaatag tttaaaataa atttttatta
    39961 ttaaacttta actgttgcta tattaatctt tttacattat aattaagtat aaggaggttt
    40021 tctatgaaaa aggcaatagt atcggttact ttgttaacag tagctgtttt aagcttatca
    40081 acaagattta tctactccac tgattattct gatttaaatc ataaggagat ggcacgtctt
    40141 atccagtcaa gaaaacaacc agtaattaag tatcatgaca atgtaaccat taataaaatg
    40201 attacttacc tagctcaggc taaaagagaa ggcattctga cagagacctt cctcatgaat
    40261 tatattttcg ctggagaggg tgagtacctg actaaaaatt caaggattat tgccgatcct
    40321 gacggagggt attggagtat cctagaaggt tatgagggag atggcggtgt taagactggt
    40381 attgacggcg tctcagagct caatatcttt agtccagaat ctaccagcat cggagagctt
    40441 caagaagcgg tgctagcctg gtatgaggct aataagtaac cgcagcttag ttaaccgact
    40501 gcttcatata atagctaata ttagctaatc ataggcctta taggcattga aatggtcaga
    40561 cccatgctca atgcttataa ggttttttag tgcttaccat ctaaccaaaa ccatagcctt
    40621 cagagagaca ttgagctgaa caagcaaaaa agaggagcaa gctcctcctc aaacattaat
    40681 acaccttaat ctacactccc acagaggaag taatttaagg ctggtgtgtc aaagcgtatc
    40741 aacccgttaa tttcaatcac tattctgaca gccaaaggtg cggctttagt tgttaatagc
    40801 tggttttagt tgccacgctt caaagatagt tgctgtaaca attgaagtag gttcgacaat
    40861 ttcaaatgta acaatacttt tatcacacct tttgcgggag cgtagattga aatccttgca
    40921 cgcaacgaca ggaccatttg acatgggaca ctgaacagag ttgaagcctt taaaaacaat
    40981 ccctaaacag ctttgggacc taatcacagt tccttgactc agctctgtca aggattctgt
    41041 tcatatcagc ttagaatgat cgctaaaaac tttttgatct aatttttctt gaacggatga
    41101 tctttaccaa gcacctgtct taaaagcttt gctttctgga ctgacgctct gctcgtccct
    41161 tggcacgttt ttctgctcgt cgctgcttgc gccgcttttc atcaactgcc cattgaattt
    41221 tctttttata gcccggttta atttttttct tttttttctt aaccaggcca atcatttcag
    41281 tgtctaattt ctgataagct ttttcacgat tctggcgacg atcacgatcg taagtatcct
    41341 gaaactcacc attttttaaa acctttggta taaaggtaat gcctagcttt tccagctcct
    41401 tgatatcaga atcatcactt ggctgataaa aggtaatggc tgtccctggc aggccgtttc
    41461 tacctgtccg ccccacacga tgcacaaaaa aggataggtc ttgaggaatg gcgtcgttaa
    41521 tcacatgact aaccccctca atatcaatac cacgcgccgc caaatccgtt gccacaatgt
    41581 attcaaatgc caggtttttg acttgattca tgatacgctt gcgctctcta ggaggaatac
    41641 ctccatgaag cttggctgcc ttcataccat tagctgctaa aaaggcatgt aagtcatcag
    41701 ctctctcctt ggtattgaca aaaagcatgg ccagataagg ctggatagcc tttagagtcg
    41761 ccaaaatttg ctcattttta tcgcgtccct tggttgataa cagccagttg tcaatcgtat
    41821 ctgcaataac ggtttctgtc ttgatctgtt caatgacagg attggtcaaa tacttcctta
    41881 aaaagggctg tagcttttgt ggaatggttg ctgaaaatac aagtatttgg atagtctttg
    41941 gcagtgctga agcaatctta tccacagtgc ttaaaaagcc catatccatt gtcatatcag
    42001 cctcatcaac aacaaaggta gaggccttat gaatggctaa atctcctgac ttgactagat
    42061 catagatacg acctggcgtt ccaatgacaa gctggggctg actaagcttt aacttgtcaa
    42121 gctgacgctg cttgtctgtc cctccaacgt aattagcaat acgaatctcc tgcttagaat
    42181 gcttagcaat ttgcctgctg gcctcaaaaa tctgtgttgc tagttcccgg ctaggtgctg
    42241 taatcacagc ttgaacctct tctttttcct ccttgagctt ttcaaaaata ggcagcaaaa
    42301 aggtatgcgt ctttcctgag cctgtctttg actcacccac taagtctcgt cctgtactga
    42361 caatcgggat aagacgctgc tgaacctctg ttggctctac aaagccaagc tcatctaggg
    42421 cctcttgaat ataatgctta aagtgataat cgtgaaatga cattatttac ctcgttttct
    42481 ttctgataat actattagtg cttgagatga gcaaaaggcg gtgcctcaag cactgcccca
    42541 gccgcttaca aataaagaat cgctaaaaca atgagactgg ctacaagacc aagagcccat
    42601 aggaaggcat caaccttcca ttcagaccac ttggctgctt taccggacaa gccgcctaat
    42661 tccagatgat gatgaaaagg agtcatccta aaaatccgac ggccttcacc atattttttc
    42721 ttggtgtatt taaagtaagt aacctgaagc atgactgagc ttgtctcaag aacatagaca
    42781 atcccaataa ccagcaaggt ccattcctga cgaagcgcaa tagaaatcgc tgctagcatt
    42841 gctcctaagg ctaagcttcc aacatcaccc ataaaaattt tggccggctt atggttaaac
    42901 aagaaaaagg ccagcaaggc accaaccatg atacctatca agagcaaaac atcaaattgt
    42961 ccctgagcat aagcgataac accataggcc agcaggctaa tcacaacaga taccgaggcc
    43021 agaccatcaa taccgtctgt caggttgacc gcatttgaaa agccaaccac ccaaaaaaga
    43081 acaaagcata ggtataaaaa gcccaaatgc caatgataac caaagacatt aatcgcatca
    43141 ataccacttg gcatgacgtg tatcacataa aagaccaggc ctccaacaat ctgaaacgtg
    43201 aatttttgct tggcagtaag gccttcatta acctgcttga agatctttaa gaaatcatct
    43261 aaaaagccta tgatcccgta aatcaataca atcaacaaga tccccgaaat caagcctagg
    43321 ctttgtccat ctcgaaaata gactaaagca aacacaaagg ataagcttgt agcaacaaga
    43381 agaaaaactg ttcctcccat tgtaggtgtt ccagccttag ccaaatgctg cttaacgtcc
    43441 tcatgcatct gctgcccccc aatttttttc aactggtaaa gccttataaa gtgaggcatg
    43501 gcaagggcag tcacagcaaa ggctatcaga cctgctagaa tggttaaaaa catgttaatc
    43561 tcctaaagtt atggtaattt ttttgacttt tttgagcgct tttccgacat caacgctctg
    43621 tttaacgaca cgtcccgagc ttgatccctt gtacttgata tcaatgccag tccatttagc
    43681 aaaggtagcc acattagcct tagtccagcc gtacatatca ggcatctcat caaaatgatt
    43741 tgataaaatc agaagctgtt ggttagcagc tagattggtc cctgcctttt tagatacctt
    43801 tttaatcttg ctgccattgc caaggacaat agggtgaacc agatttctgc gtagctcatc
    43861 agctgatttt cctgtatctt ggccaacaat atcaggcaac tgataagtag cctcgtgact
    43921 ggtatctaca gcaaccggct tgtctaaagt atccttcatc aaataggctt cctctaaaac
    43981 agggttgata atatcctgcc aaaacaccat tgcccaatgc tctgggtgct tcagtgtgac
    44041 atacatcaga aaatcaggct catcagctgg caccatagca accaccgaat aaatatagtt
    44101 tgtcaagcca ccatctaaat aacctgtacc gtccttagtc gcaatctgcg cagtccctga
    44161 cttgacagca actggtaatt gaccaacctt aaccactgga cctgatgatt tcaaatgaag
    44221 ggttccaaat tgtgggtcag tcccaacgtt aatcatgtat tttcgtgttt cactggcagc
    44281 cttttgggac accggctttc cgacaatctc cttgtctgac acccggtaag tatctgtatt
    44341 tgggtcataa atgcgactaa caaattgagg ctctagcatc acaccgtcat tagagatggc
    44401 tgtaaaggct ctaagcattt gaatttgcgt caccgaaatc ccctgaccaa aagcgctcat
    44461 tgcttgggta acaatattat cagaagggaa aatacctggg tcttcatttt ccaagccaaa
    44521 gcgtgtccgg aatccaaaac ggaatttagt taggtagttc atccatttgt catttcccat
    44581 tttttgctct agcttggtca tgccaacgtt acttgaaaac gaaaagcctt gagcataggt
    44641 catgtactgc cctgtagaaa tcccttcgtt aatcgcccaa tcctgaatgg tagcatcagc
    44701 aatggttaag ccattcgcat tgctaaaggt ctcatcagga ttaaagacct tctcatcaat
    44761 agcagctgcc agagtcataa ccttcatggt tgagccgggc tcaaactgcc cctgatggag
    44821 aatattttgc cagctatagc ttttgctgtt tagcccctcc aaggtgtctg cattataggt
    44881 tggtctttga gtagtcgcta agatttcacc agtcttagca tttactagag tagcactagc
    44941 aagctctcct tgcgccttcg actgaaagac gtccatttgc gtttctagaa aggtttgaat
    45001 aggctctgac agggtggtat aaacgtcctt accatcaact ggctttttca ctgtctttcc
    45061 tgttccaagc agggtattac cgtttctatc cttttgataa gtgatgattc catcttcccc
    45121 agataagatg ctatcaaagg ccgcctccat gcccatcttt ccaactaggc tcttggtacc
    45181 gtcctccttg ttttcctcaa gtgaagcaag accaatcagc tctgaagcaa aggtcccatt
    45241 tggatacata cggctaggac ttgctgaaaa tgcgatcccc ttgattttag ctgcctccat
    45301 agccttttgg atcgttgtca tcgtgctata agaaatacct gagccagacg gaccaaagga
    45361 aacctgaaaa agaccttttt gcttaagctg cttaataacg tccttttcct ccatacccag
    45421 ctgctccttg aggatttgag caaccttgtc atactgagac ggttgaacaa aaagcttctc
    45481 gccagtcgct gacacaaagg acttatcaag aatggcataa atgctatagg tcgtcgagtc
    45541 cacagcgata gctgtgccat tgcgatcata aatcgtgcct cgcttggcct gaacagaaac
    45601 cgtctcttga taaacctttt tggctccatc tgatagctta acaccgaatt tctgatccgt
    45661 cccgataatg atcataaaat taatcataaa gatgaagaaa ataaagatgg ttaagagcat
    45721 catgttttgc cccaccctca agcggttctg aacaggtgtc tttcgatcac gaaccacata
    45781 atctaaaaaa tatctttgcc attttgtcat agcttactcg accttcttaa tgttatcatt
    45841 tcggttacta agccctgctt tgccagcaat atcaacaatg cggtcacgtc gcgacagctc
    45901 attaacctct tgcttggcat tgttaagctc tgtcctttta tctgagatct gcctattgag
    45961 ctgagtgata tgctgctgga gctgcaattt acggctttgc aggtaaataa tgcttacagc
    46021 catcgttact gctgtcagga taagcgtagc ataaaaagcc ttctcaaccc tcgagaaagt
    46081 tctaattctt ttttgcaagg cttttgaaac tgcctgagtt cttttttcat taaccataat
    46141 ctatttccga acttttcttg cgactcgtag cttggctgaa tgtgccctat tgttagccat
    46201 tagctccttt tgacttggta aaatcggctt acgcgaaacc aattcaagct taggcttgag
    46261 ctcatcaggt ataaagggaa gtccctttgg agcatcagct gtgcttgctt ctttaaacaa
    46321 gtgctttgtc agacgatcct ccaaagaatg aaaggtaatc actgagatac ggccatcaag
    46381 ggctagcagc tctatcgccc gctggataga cgcatcagca gcaccaagct catcattgac
    46441 ctcaatacga atagcctgaa agatttgctt ggctgggtgt ccttttttct tgagctcctt
    46501 ggctggctta gctgatttga tcaatgctgc cagctctgtg gtggtgctga ttggcttaat
    46561 ggctctcgcc tgctcaatct tacgagcaat ctgctttgag aacttatcct caccatattt
    46621 aaaaaagatc cgaactaagt cattgaaatc ataggtattg acaacctcat aggctgtcaa
    46681 agccgcctgg ctatccattc gcatgtccaa gggagcgtcc tgcttgtaag aaaagccacg
    46741 ctctctctca tctaactgcg gactagaaac ccctaaatca tacaaaatcc catcaatctc
    46801 tgtaacccca tgctccagca agcgtgcctt aaggtgtcta aaattgtcct taataaaggt
    46861 cacctgtccc ttgtcaatat agggcttgag ctgctcctgc gcgtgatcaa tagccttttg
    46921 gtcctgatca aagcaataca agtgcccctt atcaccaagc agagacagca aataagctga
    46981 gtgcccagag ccaccaaggg tcgcatctac ataaatacca tctggcttaa tatccagcat
    47041 atcaacagct tcatgaagaa gtacagttac atgatgaaat tcgtttgtca tagctctaat
    47101 tgtaccatac ttcaaagggt ttataaatca aaaagtaaga gaaaagggct ttcaaggcct
    47161 aagaaagtcc ctctttatct tacttttttt ggcttagcta tccttgacat caagatgact
    47221 aagagcttgc tgcacagcct catacagcag ctcagccgat tcgagcacct gcttggtctc
    47281 ctttaacacc cgaaaatctg tcaccgaatt atctagccaa atatcaaaga tcttatcctg
    47341 tcttgtatga gataagctag aaggcaagcg caactcacta accttcagct ccttttgata
    47401 cctacagacc agatttctca cgtcccctag gctctcatta atagcactga ttttttgcct
    47461 ttttacccag cttgttagta tcccattgtc gaacaaatca aaaaatcccc acctcttaag
    47521 ctctttcaat gcctcaatga cagactcaag cttaaaagct aatgtcttta ggtctcgtat
    47581 ggtttcttgc ttctttagat cccttgtcat aagcctacct ccttagcagc tagctccgaa
    47641 tctggccatt tccattgatc aggtatttac tgctggtcaa ggcctcaagt cccatcgggc
    47701 cacgagcatg cattttttgt gtggaaatgc caatttctgc tcctagacca aagacaaagc
    47761 catctgtaaa gcgtgtcgag gcattcacat aaacagctgc cgagtcaacc agatcctgaa
    47821 aacgctctgc agcattgata ttagctgtga tgatggcttc tgaatgatga ctggtatact
    47881 gattaatcca agaaatagct tcatcaagag aggaaaccag atgaacagac atgatataat
    47941 ccaaaaattc agccgcataa tcttcctctg tggctaatac agccttgcta aacaaggctt
    48001 ttgcctgctc atctgctcgc cattccacct gctgaacctt gctgatggct gcttcaagca
    48061 tgggaataaa ggtcgctcct accttctcat gaataatcag gctttctgca gcattgcaga
    48121 cgcttggtct ttgcgtctta gcattaatca caaccttaac agccatctct agatcggctg
    48181 cttcatcaac ataaatgtga acattgccaa cccccgtctc aatgactggc accttagcct
    48241 tttccttgac cgtttgaatt aatctggcac ccccacgagg aatcaagaca tcaatataat
    48301 ccgttgcctg catcaattcc tcagctacag catgagaggt atcctcaacc agcaaaacag
    48361 catctggcgt aatagctgat gcctctaagg catttctgat aagcctgacc aaggccatat
    48421 tagagtagag agcatctttg ccacctctaa gaataatggc attattggtc ttaaaggcca
    48481 agctaaaggc gtcaacagaa acattagggc ggctttcaaa aatcatcgca ataacaccta
    48541 aaggcacacg cttttgggtt attttcaggc cgtccagatt tgtatagccc ttaatcactt
    48601 cgccaatggg atcagccaag tctgccacct gtctgacgcc ctgagccatc gcatggatac
    48661 gatctgctgt caggcgtaag cgatcgcaca gaatctctga aatcccatgc tcagccgcct
    48721 tagccagatc cttggcattt tctgtcaaaa tcatatccgt ctgggccact aattcctcag
    48781 ccaaaaaggc aagaaattga tttttatcct tcgttgtcaa ggataccaag gccctactag
    48841 ctgccttagc cctttgtcct agctgttcta ttgtcatcac gcgtcacctc tttctatctg
    48901 tttaaaccaa gtgcctagct tttctccctc caagaccctt aaaatgtctc tagggttggc
    48961 accattcatc aaaatcattt gcccctgatg ctcaaacatc atctgggctg attggatctt
    49021 acttagcata ccaccagttc caaatctgct gcctgcaccg cctgctgagg ctataatatc
    49081 ctctgtaatc tctgtcacat gactcctcaa gcgcgcgtcc tcatagatgg ttggattctt
    49141 atcaaacaaa ccatcaatgt ctgatagcat aatcagcaaa tcagcccttg taatacgagc
    49201 tacgatagct gataagcggt cattgtctcc aaattttgtt gaatgatcca tctcatcaac
    49261 actaacagca tcattttcgt tgacaatggg gacaatccct aaactaatca ggctttcaaa
    49321 ggcattggtg acatttgcca gactttctgg aaaaacaacc acatcacgtg tcagcaaaat
    49381 ctgagacact gtcgtctgat agtgggcaaa aatttgcgaa taaaggctca tcatagcaac
    49441 ctgccccaca cttgaaacag cctgctgctt ggcaagctga cttggtcttt tggccatttt
    49501 caacaggtca agcccaaagc ccatggcgcc agaggaaacc aaaataacct cttttccctt
    49561 attcattaag cttgaaatca caaaggctaa atggtcgatc ttttctaagt taatcttccc
    49621 attagcaagc accagcgagc tggttccaat tttaattaca atacgcttta catcttcaaa
    49681 ttgtcgtttc atcatattag gattatagca taaaaaacag cccagaggac tgttagattg
    49741 aagccaaaat caatcagcct atcagcttga taaaaaaaag gatcactggc tacccattca
    49801 cctaagatat aaaaatccac ctgatagcca ctccaagcag gatttccttt gtgacaccac
    49861 ataccacgct acgctttatc ctattgtaag tttaagtctg atcctcctgc attgtcctgt
    49921 catttttaat gaccatatac caacactaaa gctattgaca aaaacgcaca atacgataaa
    49981 atgaaagcgc aaacagctat atttactacc taagggccag accttgctgt aaagcgcaat
    50041 acctgacaga aagaacacgt ttcagaagta gcaagaacaa gtcacaggca tactgtctgg
    50101 cacattggcg caaaggctac cagtgttcaa caagactgga acgcaaatca ataggctgga
    50161 aatcaagtag gaaaaccgta tcatttaaat ttttggaatc ccaagactca attgttctca
    50221 attagtttgg gggcttagga cgacagagcc tgtcagtcat ctaaagcaat taattagtta
    50281 taggaataaa tcactatggt taaactatca aaaagaagca agatagctat gtcattttta
    50341 attgtctttt gtggtatatt tttcgtcgct caaaaacgat tcggttcatc agaccaatca
    50401 tttaccgtaa ggccagacgc agatttctat atagtcggtt accacaatat tgaaggttat
    50461 caattgacaa atgagcagcc gcaaaaaatt tctgacgcta agctcgaagt ggtcaaaggt
    50521 cagatcaatc aagtggttaa acgagcagag ctttcaaatc gttatctggt cttttccgag
    50581 gaggggccac ctttgggggc aataggaaga cttatcgctc ttgattttca aaaaggcaac
    50641 gtgacgtatc acccaacagc tgattatgcc tttacttcct ccggagtatc accagattat
    50701 tatttcactt ctacagcaa
//
LOCUS       DARYVE010000006        50223 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYVE010000006 DARYVE010000000
VERSION     DARYVE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50223
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(363..722)
                     /gene="rplT"
                     /locus_tag="TVW25_000295"
     CDS             complement(363..722)
                     /gene="rplT"
                     /locus_tag="TVW25_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1377968.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(783..980)
                     /gene="rpmI"
                     /locus_tag="TVW25_000296"
     CDS             complement(783..980)
                     /gene="rpmI"
                     /locus_tag="TVW25_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1377969.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(1020..1550)
                     /gene="infC"
                     /locus_tag="TVW25_000297"
     CDS             complement(1020..1550)
                     /gene="infC"
                     /locus_tag="TVW25_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1377970.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1565..1687)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1711..2391)
                     /locus_tag="TVW25_000298"
     CDS             complement(1711..2391)
                     /locus_tag="TVW25_000298"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1377971.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2406..2903)
                     /locus_tag="TVW25_000299"
     CDS             complement(2406..2903)
                     /locus_tag="TVW25_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1377972.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            2952..3149
                     /locus_tag="TVW25_000300"
     CDS             2952..3149
                     /locus_tag="TVW25_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1377973.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3136..3624)
                     /locus_tag="TVW25_000301"
     CDS             complement(3136..3624)
                     /locus_tag="TVW25_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1377974.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3669..4892)
                     /gene="pepT"
                     /locus_tag="TVW25_000302"
     CDS             complement(3669..4892)
                     /gene="pepT"
                     /locus_tag="TVW25_000302"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1377975.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(5062..6081)
                     /gene="galE"
                     /locus_tag="TVW25_000303"
     CDS             complement(5062..6081)
                     /gene="galE"
                     /locus_tag="TVW25_000303"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1377976.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6149..8518)
                     /locus_tag="TVW25_000304"
     CDS             complement(6149..8518)
                     /locus_tag="TVW25_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1377977.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8598..9761)
                     /locus_tag="TVW25_000305"
     CDS             complement(8598..9761)
                     /locus_tag="TVW25_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1377978.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9775..11259)
                     /locus_tag="TVW25_000306"
     CDS             complement(9775..11259)
                     /locus_tag="TVW25_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1377979.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11263..12504)
                     /locus_tag="TVW25_000307"
     CDS             complement(11263..12504)
                     /locus_tag="TVW25_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1377980.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDKKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12488..12844)
                     /locus_tag="TVW25_000308"
     CDS             complement(12488..12844)
                     /locus_tag="TVW25_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1377981.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12849..13538)
                     /locus_tag="TVW25_000309"
     CDS             complement(12849..13538)
                     /locus_tag="TVW25_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1377982.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13568..15313)
                     /locus_tag="TVW25_000310"
     CDS             complement(13568..15313)
                     /locus_tag="TVW25_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1377983.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15310..16317)
                     /locus_tag="TVW25_000311"
     CDS             complement(15310..16317)
                     /locus_tag="TVW25_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1377984.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16338..17546)
                     /locus_tag="TVW25_000312"
     CDS             complement(16338..17546)
                     /locus_tag="TVW25_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1377985.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17546..18349)
                     /locus_tag="TVW25_000313"
     CDS             complement(17546..18349)
                     /locus_tag="TVW25_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1377986.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18349..19284)
                     /locus_tag="TVW25_000314"
     CDS             complement(18349..19284)
                     /locus_tag="TVW25_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1377987.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19274..20428)
                     /locus_tag="TVW25_000315"
     CDS             complement(19274..20428)
                     /locus_tag="TVW25_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1377988.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20553..21401)
                     /gene="rfbD"
                     /locus_tag="TVW25_000316"
     CDS             complement(20553..21401)
                     /gene="rfbD"
                     /locus_tag="TVW25_000316"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1377989.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21543..21881)
                     /locus_tag="TVW25_000317"
     CDS             complement(21543..21881)
                     /locus_tag="TVW25_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1377990.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22179..23288)
                     /gene="rpoD"
                     /locus_tag="TVW25_000318"
     CDS             complement(22179..23288)
                     /gene="rpoD"
                     /locus_tag="TVW25_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1377991.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23297..25111)
                     /gene="dnaG"
                     /locus_tag="TVW25_000319"
     CDS             complement(23297..25111)
                     /gene="dnaG"
                     /locus_tag="TVW25_000319"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1377992.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25358..25732
                     /gene="mscL"
                     /locus_tag="TVW25_000320"
     CDS             25358..25732
                     /gene="mscL"
                     /locus_tag="TVW25_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1377993.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(25958..26134)
                     /locus_tag="TVW25_000321"
     CDS             complement(25958..26134)
                     /locus_tag="TVW25_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1377994.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26289..27101)
                     /locus_tag="TVW25_000322"
     CDS             complement(26289..27101)
                     /locus_tag="TVW25_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1377995.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27169..28284)
                     /locus_tag="TVW25_000323"
     CDS             complement(27169..28284)
                     /locus_tag="TVW25_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1377996.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28554..32195)
                     /gene="addA"
                     /locus_tag="TVW25_000324"
     CDS             complement(28554..32195)
                     /gene="addA"
                     /locus_tag="TVW25_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1377997.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32185..35406)
                     /gene="rexB"
                     /locus_tag="TVW25_000325"
     CDS             complement(32185..35406)
                     /gene="rexB"
                     /locus_tag="TVW25_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1377998.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35615..37015)
                     /locus_tag="TVW25_000326"
     CDS             complement(35615..37015)
                     /locus_tag="TVW25_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1377999.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37157..39298)
                     /locus_tag="TVW25_000327"
     CDS             complement(37157..39298)
                     /locus_tag="TVW25_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378000.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39305..40738)
                     /locus_tag="TVW25_000328"
     CDS             complement(39305..40738)
                     /locus_tag="TVW25_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1378001.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40744..41421)
                     /locus_tag="TVW25_000329"
     CDS             complement(40744..41421)
                     /locus_tag="TVW25_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1378002.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41435..42130)
                     /locus_tag="TVW25_000330"
     CDS             complement(41435..42130)
                     /locus_tag="TVW25_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1378003.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42258..42893)
                     /locus_tag="TVW25_000331"
     CDS             complement(42258..42893)
                     /locus_tag="TVW25_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1378004.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42883..43422)
                     /locus_tag="TVW25_000332"
     CDS             complement(42883..43422)
                     /locus_tag="TVW25_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1378005.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(43711..47427)
                     /locus_tag="TVW25_000333"
     CDS             complement(43711..47427)
                     /locus_tag="TVW25_000333"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1378006.1"
                     /translation="MMKRLRENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            47907..48452
                     /locus_tag="TVW25_000334"
                     /pseudo
     CDS             47907..48452
                     /locus_tag="TVW25_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            48533..48988
                     /locus_tag="TVW25_000335"
     CDS             48533..48988
                     /locus_tag="TVW25_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378007.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            48988..49275
                     /locus_tag="TVW25_000336"
     CDS             48988..49275
                     /locus_tag="TVW25_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378008.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            49268..49816
                     /locus_tag="TVW25_000337"
     CDS             49268..49816
                     /locus_tag="TVW25_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1378009.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(49995..>50223)
                     /locus_tag="TVW25_000338"
     CDS             complement(49995..>50223)
                     /locus_tag="TVW25_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378010.1"
                     /translation="PKPMPKPETKPEVKPEAKPMPKPEAQKGDKPAVPKAMEHKLPST
                     GEATAPFFTAAALAVLASLGVAVVSRKRKKH"
BASE COUNT        14877 a        11491 c         9539 g        14316 t
ORIGIN      
        1 ttatattaaa ccatatcttg tgttaaaata caatgaaatt atgacattat ggctcctaaa
       61 taagttgttt tgcattttat tattttggtg atggatttga ttaaaactag aaatcatata
      121 tctccttata tgatcatcac ttgatggact gctcaactgt ctgatacaag attaagccct
      181 ttcttcttag ttaacagcta ccaaagaaag gtaaattggc tcctttatac taaattagag
      241 atagctaaaa acatctcaaa tactcttgac aaaacgtcat gactgtctta tctagctaga
      301 ttagctaaca taaggcatta aaaatagact tagaaggttt ctaagtctac agtcgatctc
      361 tattatttgc caagctttgc cttagcagca tcagcaaggg ctgtaaaagc tgctgcatca
      421 ttcaccgcta aatcagcaag cattttacgg ttaacttcga tttcagcaag ctttaggcca
      481 tgcatcaatt gtgaatatga caagccattc atacgagcag ctgcattgat acgtgtgatc
      541 catagcttac ggaagtcacg ttttttctga cgacggtcac gataagcata gtaataagaa
      601 ttcatgacct gctcttttgc agtacggaac aagatatgtt ttgctccata ataaccttta
      661 gctaatttca aaatacgttt acgacgtttg cgtgatacaa cgccaccttt aacacgtgcc
      721 attaatattc tccttcaaat aactcttata attctagtaa atacctgtta caacccttaa
      781 tcttaaaggc cagtaaccat tgctttaata cgcttgaaat ctcctgcatg caccatacct
      841 gctttacgaa gatgacggcg ttgcttttta gtctttccat ggaaacggtg tgatgtaaag
      901 gcacggaagc gtttcaaacc gcctgaacct gtacgtttaa aacgtttagc tgatgcgcgg
      961 tgtgtttttt gttttggcat tttaatattc tcctcttaac atatagtgta atatgacaat
     1021 tacttcttgt ctgaaattgg tgcaagctgc ataaacattt ggcgaccatc catttttgct
     1081 ctttgctcaa taatagcaat atcttgagtt gcctcagcaa aatcagccag taccttagca
     1141 ccaatctcct tgtgagtaat catacgtcct ttaaaacgga tagaaacctt aaccttattt
     1201 cccttttcaa ggaacttacg accattacga agctttgttt caaagtcacc cttgtcgata
     1261 actgggctaa gacgtacttc ctttacagtt acaacgcttt gctttttgcg ttgctccttt
     1321 tgcttttttt gatactcaaa tttgaacttt ccatagtcca taagcttggc aacaggagga
     1381 acagcttgcg gctggattaa aaccaaatct acatttgcag catcagctaa agactgagct
     1441 tcagataatg gtttaatgcc taattgttca ccttcaagac caacgagacg aacttcgcga
     1501 acacgaatct catcattaat gaatagatct tttttagcta tgatcttcac ctctttattt
     1561 ttttagagaa aaacgaaagc ggacttaatg aaccaagccc gcacacataa tatcccgtag
     1621 gaatttgaca tgtagggcca gacaacctag gtcgcaaggc gagaagctct cacttctgct
     1681 tttctcatta ttgacattct aacaaataaa tcatgccatg tcaattattt tttctgcttt
     1741 ttcctgaata aattggacaa cagctgaaat cgtgataccg gtagtatcaa agataatcgc
     1801 gtcatctgcc gcctttagcg gcgaaacttg acgatgactg tccttataat cgcgtgccgc
     1861 aatctcagcc tttaaggtgt caaaatcagc tgcaatccct ttttcaatat tttcctgata
     1921 acgacgctgc gctctttctt caacagaagc aatcaaaaag atcttcaact cggcatcagg
     1981 cagcacaacc gttccgatat cacgaccgtc catgataata gcaccagtcc tagcaattcg
     2041 tcgctgctga ttcaccagct cctctctaat ctctggcaag gcggacaccc aagaaacatt
     2101 attggtgaca tcattttgcc tgatcgccat tgtcacatct tggtctccaa gaaaaaccag
     2161 ttgtgagcca tcagctgctt ttttaaaaga aattggacgc tttgccaatt cttgcaggat
     2221 tagattgaca tcttctttgt gataaccatt ttttaatgcg atataagtcg ctgagcgata
     2281 catggcacca gtatctaaat aggtgtagcc aagatttttg gcaataatct tggctaccgt
     2341 acttttccca cttgaggctg gtccatcaat cgcaattcta attgctttca tcttttcctc
     2401 tttaattatt tgatattgac ctcgtcacct ggattggcat accagtagcc ttgggtcata
     2461 tgatctgggt ttagggcctg taattgctca acagaaattc cagcacgagc tgcaatagat
     2521 gttgctcctt ctcctgctaa tactgtaatt gtctttcctg ctgcctctgt agaaggtgct
     2581 gtttcagtct tagaaggact tgttgtgtca ctagctgctg agctattaga gctcgctttt
     2641 ggctttgttt ttggttttga gctgaccttc tttgttgtct ttttctgagt tgatgccccg
     2701 taaaatcctg ttgtctcatt ttgcttgtta ctaccgctgt ttgacgtata gaagaaaata
     2761 aaaagtatgg caacaataat gacaaagaaa acacttaaca aggcagtcaa ccaaggtgtg
     2821 ctaatgagtg ctcctcttga ttttcttgtt cttgtcgcct tattgtcatc aacaattttt
     2881 tcttcccatg gttctttagc catgattctt cccccttgtt aatttaacaa aatcatatta
     2941 gaataatacc tatgaaagta tctatccttc cagaaaaatg cattgcctgt ggtctttgcc
     3001 agacctactc tgctcttttt gactatcatg atgatggtat cgtcaaattg gctcagtctg
     3061 atgagtcaag tcaactcata gatcctaatg atcatgatgc catcttagca gtaaaatcct
     3121 gccctactaa agcccttacc ctcgagtaag aggctttttt tcgtattggt aggcttcaaa
     3181 ataatccagt ttaatgaagt tatctagtaa tataacctct cccttaaaat aaggattaat
     3241 cgctagatca tctaaaaaat attttttagg ccattttctc atgtaaaaaa ggtagctctt
     3301 atcaccaaca aatagacaaa ccgttgattt agtaacctca attttggtaa ttgaggcaat
     3361 catcagtctg tgcggagcaa atagctttaa agatacgatc ttcaagacac cattattctc
     3421 aattacaaaa taacgatgca ggccaagtcc cactaatata gcaaataaag caaacaagac
     3481 aaaaacacga ctcggtattt ctgttctttc atacaataag gacaggccaa taaaaatagg
     3541 cgcaacagca attgaccaat aaataataga ccaagacagc tctggctgcc aatgatacct
     3601 tactttaccg aataatttaa tcatgctttt ccatcacctc caatccgttc tgagcatttt
     3661 gggtgatgtt aagccttttg gacaatgcca agaatcacat caactgcctt ttccatcgtt
     3721 tgcagactca caaattcaaa cctgccatgc atattttcac cacctgcaaa aatatttggc
     3781 gttggaatcc ccataaagga aatctttgag ccatcagtac caccacgaat cggctcgata
     3841 actggcttaa tagctaggtc ctccataaca gccttagcta gattcacagg tgtcatgtcc
     3901 ttttcaatca cctttttcat gttatagtac tgatccgtca ctgttacaaa tacacgctct
     3961 gctccaagct gactattcat ctcctcagct agctgtgtta caaaggcctt tctagcttca
     4021 aaggagctat cctcaaaatc acgaataata taagaggcct gtgcttcttc tacagtacca
     4081 gacatgctgt gtaggtggta aaagccttga tagccgtccg ttttttcagg acgatcgtca
     4141 actggtaatt gactatggaa atccattgct agctgcaggg cattaatcat ctgattttta
     4201 gctgtaccag ggtgaacatt gcgacctaac accttgagct ctagggctgc tgcgctaaag
     4261 gtttcatatt gtagctcgcc aagcggacct ccatcaatag tataggcaaa gtcaacatca
     4321 aaagcattaa catcaaactt atctgcacca acaccaattt cttcatcagg tccaaaggca
     4381 accttaatgt cgcaatgctc aatctgaggg ttggcaacaa gaaactcaat agccgtcatg
     4441 atttctgcaa ttccagattt atcgtcagct cctaaaaggg ttgtgccatc agttgtaatc
     4501 agggtctgtc ccaaatattg gttgagattt ggaaaatcct ctgggcataa agaatagcct
     4561 gactgaccaa gcttaatctc cccaccctgg tagctctcaa taatctgagg ggctactcct
     4621 tctgcattaa aatcagcagt atccatatgc gcaataaaac caattttccg agtcaatttg
     4681 ctgctgttag ctggtaagct tccaatgagg tagccattag ctggattgta atgaatgtcc
     4741 tgtaggccaa tagcttccat ctctggcttt agcactgtta gagcaaagtc agcttgactc
     4801 ttggtgcttg gagttgtagt gcttgctgga ttgctccttg tgttgatttt tacatagttc
     4861 agaaatcgtt ctaataaagt ttcgtatgtc atagatcacc tcgataagtt ttcgttacta
     4921 ttatagcata aaaggaccta aaatacttgc ctaagctcag ttttttacag tgctttatct
     4981 gttctgttac agttgcgttc tcataaaaag acagctgcca agaaagctct tgacagcctt
     5041 gattattcat cagcccatgc cttaatcctc ataaccattt gggtgcttgc tttgccatct
     5101 ccaagtatct gtacacatcc tttctaagcc gtactctgca gtccagttaa gctctttttt
     5161 agccttgcta gcatcagcat agcaggctgc gatgtctcct tgacgccttg gtaatatctt
     5221 gtaaggaata gacctgccaa ccacctgaga aaaggcttcg ataatatcta gcacagaata
     5281 gcctgtacct gttcctaaat tataaataga taggcttggc tcttcagcaa actttgcaag
     5341 cgcagcgacg tgtcctttag ccagatcaac aacatggata taatctctaa cgccagtgcc
     5401 gtccttggtc tcataatcat caccaaaaac gccaacacaa tccagcttac caacagctac
     5461 ctgagaaaca taaggtaata ggttgttagg tatgccctta ggatcctctc ctaaatcacc
     5521 agactcatga gctccgatag gattaaaata ccttaacaat acaatatgcc actcattatc
     5581 tgatgcatag aggtccttga aaatctcctc tagcatcagc tttgtcctac cgtaaggatt
     5641 ggtcactgat agtggaaagg tttctaaaat aggaacggta tgcggatctc cataaaccgt
     5701 tgctgaggag ctaaaaatga tctttttaca attaaaggct gtcattacct ttagtagggt
     5761 caatgtgcca gagatattat tgtcgtagta atcaagtgga atcctgcttg actctccaac
     5821 agcttttagc cctgcaaagt gaatgacact cacaatagga tgcttactga aaatatctgt
     5881 tagcagctgt tgatcgcgaa tatctccctg ataaaaggtc acttctcttc cagctatcga
     5941 ggcaacagca gctaggcttt taggatttga attgcacaaa ttatcaacca caacaacgtc
     6001 atagccagca gctagcagtt caacacaggt gtgtgacccg atatagcctg caccaccagt
     6061 aactaaaata cttcctaaca ttgattatat acctgacttt ctaataatta ctaatattat
     6121 aactgattac tcccaaaaag tatatctatc atttcatttt aaagaaatca ggataggcat
     6181 taatgtagcc cttgccttca ataagatcat attctaacag ctttaagtca gaggccacct
     6241 gcttttgagc agcagttagc tggctgtcat cgctatttct ggtatccaag acatctgtca
     6301 aaagagcgta gtaaggagac accttggaat ccgtatgctc tagcaataaa gaggtaaaat
     6361 cactggaatt aacacgaggt ctagccaatt tgttggtctg atgattgctc cagatgaaat
     6421 aatctgttaa atatttgacc tcctcatcat tcttaaagac ctgatctgga taaaagccag
     6481 gtaaatgatc accataaaac acaactgtaa taggcttgtc aaccttttcc agtgctgata
     6541 aaaaggcctt tgttgacttg tcggtaatgc ttaataaatt cacataactt tgcaggctat
     6601 ccgtctcaga ctggtccagt cctgctaggc taacatcaac atctcttagc tctgtgtacc
     6661 aagggccatg attttgcatg gtaatcactg aaaagaattg acttcttttg gggttaagct
     6721 ggtctaaaat attgtcatag gttgactcat cactatagct tgagctcatt cgtatcaagt
     6781 gctttggctt gtcagctgaa tcctctgtgg caatgaaggt atcaaatccc aatttgttgt
     6841 aaacgatttt tcgagagtaa ttgttggcgc tcgcaaggtg caaaacaatc ctatccttag
     6901 gcgaaaaggc attactaatg gcaggcgaaa acttcaactt aggaaagaca tcagaataca
     6961 aaatcgaaac tgttggattg aggttatatt ttggtaggcc aaataggctt tgaaactcca
     7021 tattagctgt accgccgcca tagccatcag aggtcattag gccactcgtt gtggtttcca
     7081 tgatatgatg gatctctgca ataggatcct tggccaattg aaccccagaa atcctagctg
     7141 ggtcagcaaa gctctcactc agtatataaa tcactgtttg atcagaaata cgctgatgcc
     7201 tttgcttatt gatatcagca gctctagctt gatatttctg ataaatcttt tgcatagcgc
     7261 tcttgctata gcctgaaggc tgattaatgg tgctggtggt aacctgcttg aaccaaacaa
     7321 agctcaagga ttgaaacctt gcattggttg taagaccata ccagtcaata tcaaagacat
     7381 tgtagactga tgacagaact ggaatacctt ttttgatttc accatcttta ttttggctaa
     7441 atacaaaaag gatagaggca aataccaaaa ggatagagcc tattgacatc agtctaagat
     7501 aaagcgctga taggatcttt tctctaaagt atcttttata caaaacatag atcagcagac
     7561 ccgacaagac tagtatcaaa ataatactaa tgatttgagt cagactaatg taattcaaga
     7621 aaaacttaat ctctttgatc catttcaaat ctgaaaacaa taaaggctca cttcgctgct
     7681 tgtatttttc aatattaaca atactgatta aagctccgat caccgtattg acaaataaag
     7741 caatgatata gttgttaatg agcaaaaaca ccagcacaaa aaagagggtc aagacaagca
     7801 cctgaaacag ggttgcacct ggaataatca ctgccccatg aaaatcacca tatgctgtga
     7861 tcccagcctg aataaagtaa ttaaagatga tccctaaaaa taagctggtc actagagcta
     7921 atctaagacc ccatcgcttg ctcaaaacct cgataaaggc tgtgacgatg aggtaataaa
     7981 ccacaaacgt cagcatataa gagcaaaagc tatacttaaa gagattcagg ctaacaaggt
     8041 ttgactgact atctaaaggc caataatcat tttgcttaat cacagtctta aataaagagc
     8101 tgttcagcgt taagactgaa aaagcctgac taagtaaaat gacttggatt cctctgtttg
     8161 attggtagtc cttcttaaac aggtattttt ttaagagaac ccctaaaata agcaggctga
     8221 ctaaagctgc cagactgagt agcatttcct gaatcgtacg attactgatg gtaaacctgc
     8281 tgttgttttt attgatggct aaggtgatat agctattagc aacagcatag tagctactga
     8341 cagctacaga aacaataagc agctttgagg aagcatgctt gatcagcaaa catgccattc
     8401 cagctattaa cactaagaca agccacgaac cataagctcc cttatttaac gtgtttttgc
     8461 ttaccgcaaa aatagataaa taaagagatg aaaggctaaa caatatcata tcaagcattt
     8521 ctagatcaac taactggcga gcttttgaaa ttatcttcgt tattataatg gtcacaccct
     8581 ttcctaactg ctaaaagcta gacattactc tctgactcag aagcgattac ctctgttact
     8641 aattgacgaa cagtgacctc ccaggtaaag cctgaaagca cctgctgatg aatggcttct
     8701 tgcaggtcac accgtttttc tttgtgctca atcaaatgat ccaactgcct tttaatatca
     8761 gagactgtat catcaatgat gattccctgt gacgggctcg ttatcacttc cttgacacca
     8821 cctctatctg ttgctaatac agcacatttc aacatacctg cctctaatac agctgtcgga
     8881 agcccttcag catagatgga cggattaaca aaaatatcag attgagacag caaagacatg
     8941 gtctcagcaa aattcagctt gcctgtaaag atgatggact gatcctcttt atagctatct
     9001 cttagtgaag caagcaaggg accatctcca gcaaccacca agacagccct gtccttatat
     9061 gtcagctgct caaaagcctc cagcagcaaa agaatcccct tttccttgat cactcgacct
     9121 gcaaaggtaa taatgacctt atcctgcaaa gctggtaaat aagcctttga cttaaagacc
     9181 tcataaagat cagaatcaac tgaattgtag atgacgcctt tggcttttat tccaaaggtc
     9241 ttgagccatg ccatactgcg cttagacacc gcataaaagt cgggctgata ggctttgaca
     9301 aaaaaggtaa ttacatgctc atagacttta gcaaacaagt ctagtagctg gtgaccttta
     9361 acattttcgc ccacctgaac atagccacca ccatgctcga tcacaatact agggatggct
     9421 tttcttttgg ctagcttcaa gcccatgagg cttgtcaaat aaaatcgtgt attgcagatc
     9481 acaaagtcaa tacgttcttc catcagctcc gccagcatgc tatgatacag atcattctta
     9541 tctaaaatcg gatagcgctg cttaaatagc tgctttgaag gaaatcggta ataagtaatg
     9601 gcttgatctc tttcaatagg gctcagctgg tggctgttgc tggttacaat gatgatacgg
     9661 tagcctaggc tcactaattg ttgcgctatt ttttctgtat accgctctac tcctcctaga
     9721 tgagggcttg taaagccgct aaaaatggct attgttttca aagcttttcc cttcttatgt
     9781 ataatattgc agcattgttc gagtaatcat acctaggatc aatagcaacg agccaataag
     9841 aacctgttta ttacttaata ggccttgggc cttttcaagg tatttgttat tagaggccag
     9901 caagaccaac actaaaggga tcacacccaa aaagtaccta tcttgaaccc ctagcacatt
     9961 aaggtctcca actggcgtaa aggtcaaata aaggctaaag gtaataccgc ctattattcc
    10021 taaagacatc aatcccatac caaagcgaga taaggtcggc agctgaagct tgttggcatt
    10081 agtgatgaca acagcaaaat aataaaccat actaattggc atgagctcta ccataccgta
    10141 tgataaaggg ccaaacatgt aaatccctga aggattaagg atatgagcca acgtgtgtct
    10201 tagcagcata aagccatata ctatagggtt ccttaacaca gtcagtagct gctctttagc
    10261 attgaccttc tggagaaagt cagccatatc cacctgaggt gacttgattt gaccatatac
    10321 ctttaaccaa aaaacagtca caaccagcac cgtcagaatt gacaacagct ttagcagaaa
    10381 cgtgcgagag gcttttgctc caaattgacg tgaagggata aaaagcagca acaaaatcaa
    10441 taaaatataa ggcagcttag taaaggtaat gattgagcac agcagggtat accaaaagag
    10501 cttggataag ggaatctttt cagttgtagc catctgaaca aataaagaaa tcgtcagaat
    10561 aatcaatcca atagagacac aatcctgatt ataagaacca gcaagataga tattcatcgg
    10621 aaggagactt cctacagcaa gcagctgctt gcctgctgtc agcaatcgta aggcaacaaa
    10681 aaccaagatg gcataggcaa gaacattaca aagcctacct aaaaggtaag ataagcccat
    10741 ggtcaagcct aagctccttc caataaataa gcctattacc tgtggtatgt aggcaaagtt
    10801 ataatagcca tttgttgagc gaatttcctt aaatgaaata gcctcatctg tatggtctct
    10861 gctccacagc tgaaagcgta agggcttgcc attgttgtgg tccataagat taatgtcatc
    10921 agtcaccagc agctttgagt catcattggt taaattaaga tttccctcag ataagtataa
    10981 ggctcttgca aagtgaaccc tctcatcagg aatatcattg atcggtgaga tgaaggcaga
    11041 gacagaaccc ataaccacaa taataagcac tgtcgcatat tccatatttg aaggtaaaaa
    11101 gataatcaaa agcgcagcaa ttgcaactaa tattgctaaa aatttaatgg gtaaatccgt
    11161 tgattgcgta tataaaagca gcaacacaag aaaggcacca agtaaaacaa gcaaagcctt
    11221 actcgccttt tgcaatttgt caaataaggt atctaacata tcctatttcc ttttttccat
    11281 aatgtacaag ccatatgaca atagcagcca aatcatcatt gaaattataa aaccataggt
    11341 aactccaatc accccaaagc ttctagccaa agaaccagtg atggctagtg aggagataaa
    11401 ggatacaaca taaggtatca caagcaagtg ctgctttctg ataatggtaa tcaaattatc
    11461 aatataagtg gcaaaggtgc tgataatccc tccaaaaata agaagcataa aatcaagctg
    11521 gtaatgcctt aaatcaatac cataaacaag cgatagcacc ggcagcccca caaaatagct
    11581 agcaagcaag atagctaggc ttgctaatag cagcactaga ctgagacgac gctctaattg
    11641 tgcaaagctc ttcttgtcct cttttgaatg gtaaatggcc agctgagtga tcataggcct
    11701 taaaaacaag aaaatcaggt taatcataaa aataggcata aacaaaatat taaattctgt
    11761 ttgaacaccg gctgggatca gctgctttga gtaaagctgc tccaaaacaa acttgggctg
    11821 gttgtagata taaatgagta aaaaaccatt taaaaagagg ggaaagctct ccttcaatag
    11881 ccctaagatg ctttgagcat caatacgacg ctcaaggctc gtaaaggaaa ctgaaggggt
    11941 tatgtcaaat agcacaatac aagccactga aataagacat atcacgatca aagacaggac
    12001 tagctgcttg gtcagaacca gacagagcgt aaagccaaga atcaccagca tatttcgata
    12061 aaacaaggat ttgccggcaa tatctaagcg ctctctttgt tgaaacattc cttgaaacac
    12121 atcagaaatg gcatctgtgc aacgatacaa gcaaatcaac caaatcacta gccccttaaa
    12181 cccactatag ctccccaaat aaatatagag cactgaaatg gctatcatca agaaacaggt
    12241 gactagtctt gtataaaaat agtctttgaa gcggtacttg tgtaatatat ccgttgattg
    12301 gaaatttcta atctgaaata agccaatagt aatcagctga tttccaatag cataggcaaa
    12361 gctaaaggta tctgaagctg atttagataa gacccgagac acaatcatca gtaaaatcac
    12421 tgatattagt gctgtcgagc tggttcccaa cacattccaa ataaaaatcg actgatccga
    12481 ttgaatccta ctgctggttt tcatcttctt cctgcttttc cttctcatta agggctaaat
    12541 actgaatcat ttttttaagc ttaatctctg tccgagacaa tttttgagtg ataaaaaatt
    12601 ggttgatgat gagtaaaaaa atgattgata gaaaaacaaa atttgccggc gattcaaagc
    12661 ctagcagcct tgaaaaataa accgcagcat ttggaaacag tgacagcaaa agcactatta
    12721 aagagaaaaa gagccaaaaa aagctatctt caattaaaat tttggatctg cgaatgctat
    12781 ctagtataaa catggctgtc aataatgcaa caatgatcaa aatcagctgt aacccaataa
    12841 acatcctctt acctctttct aaagttttga attaaaataa tcgaaataaa catgtgaacc
    12901 atgtatttaa tagatctaga aagagtgagg tagctttgac cagccagcct atcattcatt
    12961 tgcacctgaa cctcactcac cctatagcct tgtcgaataa gataagagat cgtatcaggc
    13021 tctggagtat agttaatatt agttgcaaaa atcctgatca gctcctgatt aaacattctc
    13081 ataccagagg tcggatcggt aatacgcttt cctgtggtta gcttgataaa aaagctaata
    13141 aggctattgc ctatcattct caaggatcta ttcttttcag cactgacaaa ccttgatcca
    13201 atgacacaat cagcaccagc attaattgaa tcgctcaaag cctcaatata ctctggcaag
    13261 tgttgaccat ctgcatcgaa ctggagtgct ttagcatatc cctttttaaa ggcatattta
    13321 aagcccgtct gaatagcacc agataagcca agattttccg gcaaatcaat gatattgtaa
    13381 tggttatgat gacagatctc tgatgtccga tccgaagagc catcattgat aatcacataa
    13441 tcatattgag gaaaatgtct tttgatattt tccactactt tttcaatcga ctcctcttcg
    13501 ttatatgctg gaatcattac caataagtct tttttcatat cgtcaaatat tctctctatt
    13561 cattcgtcta aacgcgtctt tttagcaatc gctttatgat ataacggata gccttagctg
    13621 gcccaatcac aatatatttt aaggctcctt ttatacctcc catatagtca aaatcgacat
    13681 aggtatgtgg cacactgcct tcacgcaggt ttaagagctt attatcaata aatggtgtca
    13741 atagcttttc atttcttgaa attctaaaat catagtgtct gtcccaagca atataaatta
    13801 agagacgttc aatggcatgc aggatcgaat tttgagacag aggctctgct ggaatatcag
    13861 cctcacttag gtctaagtca aacaagggct ttaaggcatc gtatttaaac caaacaaagg
    13921 tgccatagct catgacaaag gtatccatcg tctgaaaatc aatgcgtttt gtaagcccca
    13981 ttgcctgcca aagctgattc atttcagggg caataaggtg ctcattccaa gcgtcaacaa
    14041 ttttattaaa acggaaaaaa cttggaatat ctgctatcac aataccgata gcatcagcag
    14101 ccagtgctgt taggatttga tccgccggct tcaccatcat atcaatcaat tcagtgcgcc
    14161 aggattggcc cgcccaaaaa tctgcttcct ttgatttttt ggtatgaaaa tgcccaatat
    14221 aatcatattg agacaatcgt tcctttaagg tcagcattgg caagacatct cgaccgatat
    14281 ttcctgtcac caatatgtca gcacttgccc cgctttctcg tagaatttct ttaatctcag
    14341 cctttttagc cttgctatcg gtcgttatga gcaagtcata atcaaaatga aaatgactaa
    14401 atgcttctaa aaactctgac aataaatcaa cataaaaaac atgaagatga acagcaattt
    14461 tcttgctttg atcaatgctt atcggctgct ctggcaggta tttatgtgcc agaagatact
    14521 tagcatctgg tggatggacc tgcgacatat gatccacaat caagctggca gggtatgtcg
    14581 ttttttggtc aataaaatcc aaaaggtaag gagcaatgtg ctggttagcg tcaatagcct
    14641 taaccttgat aaagggcaca tggtgcttta agatggctgt cggattgtaa taagagaaat
    14701 ccgcatgcag catagaggac gagtcctcct tggtcgtatc aaataccgtc ttgtatcgaa
    14761 agccagcctc cacaaagaca gtggttattc tggtttcata attgtggatc acatcttgaa
    14821 cgtctgttag ctcaacgata ttttcccaaa actgcctaaa ttccttacta tgaacgaggg
    14881 attttttgaa gctgataaaa tagctctgaa tatgctcttt aaaggccttg gtcgctcgat
    14941 tgttggtcat gccccagaaa tcaactgctt catctgcttc atatttgaga taataaggct
    15001 tcatatccca aagcggacca aagcaggtat cgttcataat cgtgattgag tcaaagtcaa
    15061 caaggtgctc acagcctaag gccttcatac catcatgcca agctgcaaaa tcatagcctt
    15121 tattgtgtcg ttgaataaac tgatccatca aatgccgctg ttcaagctgc tcaaggtcct
    15181 cttgatggat atcactattt gaaataaaga caatctttga aaacaaggct ctcatctgtt
    15241 cgagctggta ataaacatga tcgcttacct tatgatattt attgaaatgc acatacaata
    15301 atagacgctt cattttttcc tcctaaaaag ctcaagcagc tttgataggt acctccaacg
    15361 acgtgaggta accacacaat tgtattgatg ggttagcgct tcaacctctt gcctttgatg
    15421 atcaagctgc tgctgtagct gatctatctt ctctgcctgt agagcctcct gatctgcaag
    15481 cgtctgtcgt aattgatgaa tggtatgact taattgatga atccgaattt catttttagc
    15541 gtcctgcttt agtaatgctt ttgcaatagc ttccatattg gctgtagggt atttagacaa
    15601 ataggacagc tgggtctcca acaagccttg aatacggccc agcatttttt cctctgctgc
    15661 cggccttgaa tctgaattat ccgtcattcg ataaacagtg gtcgaatcct tcaaataggc
    15721 tagagaggtt gactgaaaca gctctaattg tatgtcaaaa gtgtcgtctg acgtctccaa
    15781 atcaatgcgt tgattaactg ccctcatcag atcagcctcc accagccagg ttgatgacat
    15841 ggtcattcct tttaaagcaa gcattttctc gtaggtgtct gttaagggag taaagccact
    15901 ttcaaaggca ttgctctgaa taagcttgcc gtcagtatct acaaaatcaa agtcagtatt
    15961 agaccatttt gaatctggtg agctatccag caaatcaacc tgcttttgta gcttgagagt
    16021 atcagtccaa tagtcatcac catcacatct ggcaatatac tgtccctttg cctccaaaca
    16081 agccttgacc caggttcttg caatcccaag atttacctca ttaacgatga gtcgtatacg
    16141 atctggaaag ctggcttgat agtccatgag gatctgtctg gaatagtctg ttgaagcgtc
    16201 gtcaatgaca ataatttcaa catcaaagct ggtctgttgg gctaaaaagc tgtctaaggc
    16261 ctctgaaatc caaggcccct tattataatt ggtgcaaata atagaaactt ttttcatagg
    16321 atgctttcta atgacaatta ttgattaatg agccagctac catttctttg atataagcca
    16381 ctggcagagt ccaaagcaga caggtcatct ggagcaatat cgtttcgttg aagcacgact
    16441 aatggggaat gattagctgt taaaaagagc agcatttgcc cgttttgatc gcgaacagtc
    16501 acctcaagct ttaatttgat atcatttagg tgtgagagct gacactggta ggatatgttc
    16561 ttatgaccag gaccacttgt cggttgatcc tgtgaattgt cattatatac ccaaatattg
    16621 cggtcaatat cagtcaacga aaaggcaaca taggtaggct cgtcctttaa gacatgatag
    16681 gaaatctcaa aggaaatggg ctcatctgga ctaaggcttg gcttagaggt caacctcacc
    16741 tctaactggc ttgccaaatc agacacaggc tcagcagcag ctccttgctc agcatttttc
    16801 aattcagtat tatcaacact gtattggtta gcgacatcaa agggttcgcc gtaagccttg
    16861 acaaggccat tttcgatgag gactgcgcga ttgcagtatt ttttgacagc ccccatatca
    16921 tgggtcacta gtatagtagt cttgccgctc tccttgcgct ccatgaagta gtcattgcat
    16981 tttcgttgaa aggcctcatc accaacagct aacacctcat caagaatcag cacatctccc
    17041 tgtgccttga tagcgacaga aaaagcaaga cgaacctgca tgcctgagga ataatttttt
    17101 aatttttgat tcatgaaatc atgcagctca gcaaagtcaa cgatatcatc atacatatca
    17161 tcaacctctt ctgtggtaaa gcccagcatt gcgccattca tgtagacatt ttcacgccca
    17221 gtcaactcag gattaaagcc aacaccaagc tcgatgaagg acaccatttt cccctcaact
    17281 gtgacctgtc ctttttctgg aacataaatt tgagaaataa tttttaataa ggttgatttt
    17341 ccagagccat ttcgtccaac gatgccaaaa aaatccccct tatacacgtc aaagctaata
    17401 tcccttagca catgctgctc ggtatagccc ttaatgcctt taaaacggtt aacaagagca
    17461 gtacgaaagc tcttggttgc ctctgttggc agcttaaagg acttactgac atgatcaact
    17521 gttactgcaa tttctttatt agccattaga taatctccgc aaacttctta gcatttttat
    17581 taaacactgc taccccaagt gctaatagga caaatggaat gaggtaagga atgatgatat
    17641 agcaccaatt tgtcgacatt tgccaaatgg tcacattagc tctgtcaatc agcagatacc
    17701 gcaaatcttg aataatctgt gctaaaggat taagcatcaa aatcttggca gcaagagggt
    17761 gtcggtcaaa cacaaaggta atcgggtaga tgatgggagt cacatacata cctgcctgca
    17821 atagaacctc ccaaacctga gccaaatcac gataataaac aaagacggta gaaagcatca
    17881 aggccacacc aactgtaaga acagccagct caacaaagag tggtaaggcc agataagcgt
    17941 gaggagataa agtaactcca ttgatagctg caaaaaccaa aaccactaat aggttgattg
    18001 aaaagttaat caatgctcct aaaactgctg aaaaaacgat agtatgcttt gaaaaattca
    18061 attttctaag caggtctcct cgcgatacaa tagagaccat tcccatactg gttgcttctg
    18121 agaaaaagga ccaaatcaca ttggcaagta aaagagcaac cggaaaatga ggaacgtcac
    18181 caccagttcg caaaaacctg ataaacacca aatacatgat ggtaaacatc atcaaaggct
    18241 ttaagataga ccacaaataa ccaatagcac tgccctgata ccttagttta aagtctgttt
    18301 taacaagctc tttcaaaaga atacgattct ttttactcaa taattccatt attcttttct
    18361 cctatagcca aatttggtca tgatcaatgc cataaaaaca agggtatgaa aggcacgatt
    18421 tttccgaaag ccatacgctt tgaaatcaga cagacgctga tagaaaggcc tatccaaaag
    18481 ccctacgtaa gcctcaatca atcttctgtc agccggattt agctgcaagt ctagcaattg
    18541 ccttgcttga tgttgactag aaacaataag ccaccaatac ttctctatga gcttatgggg
    18601 cttacgccac tgcttcagtc gcttagacca ggttcttgcc cctaaaacat tagcatcatg
    18661 ctgacgatag agctctgttg ccacatctag atacacaagc tctccctgcg ctgctgcaat
    18721 caaggctaaa taccaatcat gcatcaccac atgctcacag ctcacccact gctctgccag
    18781 cgcgtgatta atcatcatag tgccgcctgt gactgtgttt tcagtcaact cctggactag
    18841 ctgagtatta gcatgatgtg attgtgtttg gatcatactc tcatgacgta cttctaagtc
    18901 ttgattgacc acctttaggt ctgtgtagac tagtaagggc tcgcttatct tgtgcttttg
    18961 cgcttctgcc agagtaagct ctaatttatt gtctaaccac acatcgtctt ggtcactgaa
    19021 aaaataaata tctgcctttt catatgttaa aagggtgtga aagcttcgaa tcacaccgag
    19081 gttttcctgc acatcagcat taatcaagca aattctcgga tcctttttag caaaagcctg
    19141 aatgatggca agcgttttat cagtagagcc atcatctctg actaataagg tccaatcctg
    19201 caccgtctgc ctttgaatgc tttgtatttg ctctgctaaa aaccgcgccc cgttgtaggt
    19261 agacattaaa atattaatct tcatctaaaa ataaggcctc atactctcct acaattttct
    19321 cccaggtata ttctttggca atgatttgct tagctctttc tcccaaatca gcaaacgatt
    19381 ccttttgatc aaccctgtta atcagtccag taaggctgcc cttttctttt gtccaataaa
    19441 gggctgctgt tttagcaact gattgattaa aggtcactcc caaaaccaaa ttaagctggg
    19501 tatgggctag ggcctccaaa agacctggat tggtacctcc aacctcatgc ccatgaatat
    19561 aagcaaaagc atgctcacga atataagcta aaagctgctt atcatactgt gttccaacaa
    19621 attttacacg cgcgtcctta tcacagccag ttgcactaac cagccgctca aaataaggat
    19681 ttttgtcatg gttgcaaata ataaccaaat cccgctgagt agatgatgcc ataaactctc
    19741 taatggctgt ttcatagttg ttttcaggaa caaagcgccc caaaatcaaa tagtattggt
    19801 tttctgttat ctcaaatgtt tgaaagtaag ttctgacttt ttcatctgat gtagacaaac
    19861 aagaccgccc tatttctgtc ccataggcaa taaaagtcgt ttttgcccaa ggataagact
    19921 ttttgatgta ggcttcaatg ccaatattat ctgagatgac caaatcagca tgctttgtca
    19981 tttgcttttc ggcgtatttc aggtattgct gaacaggctt agaccatttt gaacgcttcc
    20041 attccagccc atcaggatta atcaacaaac gcccaccacg ctggtgaatc tgctttgcaa
    20101 agggggcaat aaagcctcca atggtattgc ctagaacata aaaaataggc ttttgaatat
    20161 gatacctatc aatataagct aaagcgtgac taatagccat catatcataa gcaatcactc
    20221 tagctggacc gagcttagga ggattgatat aaaaacaatc tgctcccttg tacacaaaat
    20281 gctccttgtg cttgctatcg ctcaagcagg caatatgata ggtaatgctt ttgttggtct
    20341 gattagtgac taattcttca acaaaggtct caaaaccacc atactttgct ggtaaaccgc
    20401 gacttccgat gatgaaaaca tcctgcatag cacactgccc cattctaaaa tataattagt
    20461 agtattatac catataaaca ggtcttatgc gacataaaat ccatgaaaag agagccaatc
    20521 tcctagatca gctctttagt gctatcgctt attcattgct gttgcttgta aaaagcctcc
    20581 agggcttctt gccaggtagg aatcacaaaa ccagttgcct tagccttatc aagattcatg
    20641 gttgagttaa agggtctttt ggctttagca ggaaaagccg atgaatccac aggcacaacc
    20701 tcgacagctg tctcttttaa gatttctcta gcaaaatcat accaagtggt gtcttcttta
    20761 gcatcatttg acaaatgata atagccataa ggcttgcgat tgtctgctag atgacacata
    20821 aactcagcca aggtcctcgt ccaggttgga cgcccatgct gatcattgac gactgtcaag
    20881 cgagagtggg tcttagcaag gttttgcatg gtaaacacaa aattcttgcc ataatgacca
    20941 aacacccatg cggtacgaat aatgtaaaat tgcttggtat atcgctcaac agccagctca
    21001 cctaagcgct tagcacgacc gtatgctgtt tgaggatcag gagtatctgt ttctagccat
    21061 tcctgaccag ctggcttttg accatcaaaa acgtaatccg ttgaaatata aaccaaggtc
    21121 gccccgtagc gctcacaagc cttggcaata tgctcagtac cagctacatt gatagcttca
    21181 ttcagtgctt ttccttcttc ttcagcagca tcaactgctg tgtaggctgc acagtgatac
    21241 actaagctag gcttgacctg agcaaaaacc tcctctactt tagtcgcgtt ggtaatatcc
    21301 atttcagcaa catcaacagc aacataatcg acgcttcgtt cgtctaaaag ataacgaagc
    21361 tctgttccta attgaccatt acttcctgta attaaaatca tcttttctcc tttgtaaagg
    21421 tcttatttct ttgagctaat cacgcagctc actcccatct aatcctaaga gaggcttttt
    21481 tgatcagctg accctagcaa gacctttgtt gtggtatcgt atcagccttg ctttttatct
    21541 agctaccgaa tacctagggc aattctcgca tagcggctca tcttttcaac gctccaaaca
    21601 gggtaccaga ccaactttac ctcaaccttg gtcacctctg gaacatctct catcgcatca
    21661 tgaatatgat cagtcaacaa atccgccaaa ggacagccca ttgtggtcaa ggtcatgtca
    21721 atctcggtat gaccattgtc atcaaaacga atctcataga ccaagcctag attcacaata
    21781 tcaataccta gctccggatc aataaccgtt cccaaagctt caagaatccg atccttgata
    21841 gctgcaacct gctcttctgt gtattttaat gtttcagtca tagctattcc tttcactttt
    21901 ttcgaagacc tgatatgatg ccaagtcaaa aaccagccca aagaccagcg cattcagcat
    21961 acctatgatg ccctaagctg actaacattg atagcctctt tttagtcacc cttacattaa
    22021 cactagtctt tagctactgg ctagcaaagg taatctcata aaccagtaac taggcttgga
    22081 gtcgttgacc ataggccact caccgtcaag gagagataac gcatttcggg ctcgtctcct
    22141 atttttagct cgccgttaaa aaggtccacc ggaccttttt aatcctcaat gaagtctctg
    22201 agctgcttgc tgcggcttgg gtggcggagc ttacgcaaag ccttagcctc aatttgacga
    22261 atccgttcac gagtgacatt gaagaccttc ccaacgtcct ctaatgtacg cattttccca
    22321 tcatcaagcc caaagcgcag gcgaagaaca ttttcctcac gatctgtcag cgtatcaagc
    22381 acttcgtcta attgctcacg aagaaccaca cgagttgtgt aatcaacagg attttcaatc
    22441 acttcatctt caataaaatc acctaaatga ctgtcatcct cttcaccgat tggtgtttca
    22501 agagacactg gctcctgagc gattttcaga atttcacgca ccttatcagg ggtcatctcc
    22561 atacgctctg cgatctgctc tggagtagga tcctgcccca attcttgaag gaggttgcgc
    22621 tgctcacgca ctagtttatt aatggtttcc accatatgca caggaatccg aatggtacgt
    22681 gcctgatctg caatagcacg agtaatggcc tgacgaatcc accaggtcgc ataggtcgaa
    22741 aacttgaagc ccttagaata atcaaacttg tcaacagcct tcattaagcc catgttacct
    22801 tcttgaatca aatcaagaaa ttgcatgcca cgccctacat aacgctttgc aatcgacacc
    22861 accaaacgca gattggcctc agcaagacgc tgcttagcct ccatatcacc agcggctact
    22921 gcaaccgcta aaaccttttc ctcatcactt gtcagcagcg gcaccacacc gatctccttg
    22981 agatacatgc gcacaggatc gttgaccttg gctgaattac ttccgataag ctcctcgtct
    23041 gtcagctcct ctggcttagg ctcttcaacg acgtatttag atgagggatt tccttcctta
    23101 tctgtaatgg aaatgccacc atctgtcaaa cgctcaagca aatcatcaat ttggtcagca
    23161 tctaaggtaa atggaatcac gagtttttct gtgacctcat catcagtagc tgttccttcc
    23221 tttttatgat gacgaataaa ctccgcaatt tgaacgttaa aggttgtaat ttctttttct
    23281 tttgccatat tttcctctat tccatttttc ttttttcagc aatgaaacgc tctaaagcct
    23341 ctagagccat ctggtggtca cccttactgc tagattccct aatctgcttt ccttgcctat
    23401 gcagctctct ttgctttagc aatgtcattt gccttgataa aatatcctca atctcaccgc
    23461 tagctatctc atcaggaaga ttttcctcta aaacccggta ataggcttgg ttaacctctt
    23521 cagacagttg cgataggtca taggaggtaa tctgccctgt ggcctttagc tgctcataca
    23581 gcgtctgaag ggctggtgta tcaaaataaa aatccggccg atgacgaaat tcattgagca
    23641 aatagtcgtg atgaagcagg cgatgcagga ggtgactttc tgttttagcc aaggctgtca
    23701 tgcttttgtt aatcggtaag gtcaccagag atgcctttgg ttgactagcc tgtccttgtt
    23761 gtaagctttg cctatcttgt agccttaaag catttaccga ttgctccacc tgaaaataat
    23821 caaaatccgg cagcaaatca gccaccttat taatatacga attttgtgcg gtgattgagg
    23881 gtgcttgagc aataatctgt gatatatgct ccacataagc aatctgcgat tgcaggttat
    23941 ccatattttc aggcttcagg tgatcaatca aaaactcaac actgctaatg cgcgagtgct
    24001 ggagcaattc tgctagagcc tctggtgaat gctgctgaac aaattcatcg ggatccattc
    24061 tatttggtat tttcacgatc tccacttgaa aatctgccag cagctcaaga gacttggcaa
    24121 tagcattttg cccggcgtcg tcaccatcat aagtcaatac aaccttttgt gtcagctgct
    24181 tgaggtgcct aacatgctct ggcgtcaagg ctgtccccat agaggcaaca gtattaccat
    24241 agcctgcccg gtaggctgca ataacgtcca taaagccttc catcaaaaag acctcatgag
    24301 tcttagcgat tatcggcttg gccttatcaa ggtggtaaag ctcataggac ttgttaaata
    24361 ggaccgtagc ccttgaattt ttatacttgg cctgctgctt ttctatatcc tctcttgccc
    24421 agatacgtcc tgaaaaagca atcatattgc ccttatcatc acataaggga aacatgattc
    24481 gatgacgaaa ggcatcataa atagcatttg attgttcaga aacatgaaac aagcctgagg
    24541 ctgttaattg cgcctcagta tacttttttg acaaggcttg ataaaggtag tccatctcgt
    24601 taggcgccaa gccaatccga aaatactcta ttagctgatc atcaagccct ctttgataaa
    24661 gatactcctt ggctctttgg ccaatctttg tcgtcatcaa aaccgcatgg taaaacttag
    24721 cagcatcttc atgaagatca attaaagcct gatgagggtg ctgcttttga ctcaaactag
    24781 tctgacttgg agcaacagta actgccatac cagccttatc agccacaatc tgaacacttt
    24841 ctaaaaaagg aacctgccga tattcctcaa taaacttaaa aacatccccc gacttaccgc
    24901 agccaaagca gtgaaagaac tgtctatctt cgatgacatt aaaagagggt gttttttctt
    24961 tatgaaaggg acacaatcca aggtagtgcc gaccagcccg cgatagatgg acaacttctc
    25021 caataacatc aacaatattg acattatgct tgatctgaga aatcatctct ttgtcaatag
    25081 ccaaaccgtc acctccccac aaaaagccca ttgtaaattt acatttcatt ataccattga
    25141 aaatgagctt tgtaaattgt aaaagcacaa tccttcatca tctaaagccc gctacatcaa
    25201 gcaataagct atgctaaagt attgacgtct cttatgatca ctagcttgac tagcagtaca
    25261 gcattaagta gctcatcagt ccttgataag ctcttctatt agcctttttg acctatttgt
    25321 gctatgataa gattatctga aaaaagggga gtcaatcatg ctcaaagaat taaaagcatt
    25381 tttatttaga gggaatatta tcgacctagc agttgcggtg attgttggga gcgcctttag
    25441 cgctattgtc acatcatttg tcaacgacat tatcacaccg ctgatcctaa acccagcctt
    25501 gaaagctgca aatgtggaaa acattgctca gctcgcctgg aatggcatca aatatggcag
    25561 ctttctcagt gctattatca actttttaat tgttggtacc agccttttct ttgtggttaa
    25621 ggtcgctcaa aaagcaatgc ctaaaaaggg agaggaagag cccgctaagc ccaaaacacc
    25681 aactcaggaa gaattattac ttgacatacg tgatttgtta gccaaaaaat aactcaaagc
    25741 tcttacagca gctggacctg tccggctgct ttttgatata caagcacaga gcacttagcg
    25801 atcaaaagat aatagaaccg gctctatttg ctgttttagc atatcattgc tatttttatc
    25861 agcagcaagc taaggtaaaa aaagacaaac tagtatcctc atactggttt gccttcaaac
    25921 taaggcagcc tacaaagggc cgcctttttt atgatgatta gaatttttta cgtttgcgag
    25981 ctgcttctga tttgcgttta cgctttacag aaggtttttc gtagaattca cgcttgcgtg
    26041 attcttgaag agtaccagct ttagtaacag aacgtttgaa acgacgaaga gcatcatcaa
    26101 gcgattcatt cttacgtact actgtttttg acatatgttt cacctcctca agatattgta
    26161 acattttcac gttctagctt atcttacatg atttttcgga aaaagtcaat gatcttttct
    26221 tgattttgag gtcattctta aaaaaatacc ttaaaatttg ctgctgcatt aggcatcact
    26281 tggcaaggct attctactgc atttcctgtt aataatgctg cttcttgaat aaaggccttg
    26341 tatttgccat ccttgtttaa ttgcttgatc accttattaa tggtttgcct taggtcatca
    26401 ctcccctttg gcatagctac agccttagca tctccatcac ttgcctgcaa tttaaatggt
    26461 gctaaagcca ggtctttatg ttgagctaaa aagcctgcag ctactggtgc ttccaaatca
    26521 acagcctgca cctgcccaga tttcaactca ttaatagcct cacccatcac agttagagaa
    26581 acacagttgg ctttattaag ctgctccttg actaggccct cctcgatgct gcctttttga
    26641 acagccacct ttttgccaac taagctatcc ttattagcat aatgcttggc atctgacgct
    26701 ttcaccaaaa tagcattttc agtttcatag taagcctcag aaaaatcata cactttggca
    26761 cgctctttgg tgtaggacaa accagaaatc gctatatcca ccttaccagt ttgcagactg
    26821 gataagacat tatcaaaatt catagcagag agttcaagct taacccctag ttcatcagca
    26881 atggcctgtg ccagctcaat gtctgctccg acaatagtat ccttgccgtc aaccaaggcc
    26941 ttaaattcaa aaggagcata gtcagggcta acagcaacca ccagctttcc cttttcctgg
    27001 atcctgtctt gaaggctcgt cttgttagct tggccacaag ctgccaaagc aaaaacagat
    27061 accatagcaa gtgctccaac taataatcgc ttcatgttca tattataatt attccttttc
    27121 ttgttgatga atcttattat attgcattat tattcaatgg tcaagttttt attgaatatt
    27181 tttcaagcac tgcgatagtc tgcttaatcc tgcctgtaga acctgcggct gacagcaata
    27241 gccgattctc acatgatttg cttgattaaa gcgatttccc ggaacgacca aggtaccgta
    27301 atcctccagc agcctcaaag caaaggcttc catgtcctca tctatatcta gcctaacaaa
    27361 ggccgttgag acctcattcg gtctatggta ggaggccctg gcttcacctg ttatccagtc
    27421 ctctaagata gcaaggttag tcctgataat ggcttgattg cgctgcaata gcttgtcagc
    27481 atgcttcaag gctagcgaag ccaccatatc atcaaaaaca cctgcacaga tcattgtgta
    27541 atctcgatat aacctaagct gatcacagat ggtctcagaa gcggctaccc agccaactcg
    27601 aatgcccgga atcgaaaagg tttttgacat gctattaaca gtaatcccct tatcatacaa
    27661 atctgccacc gctaaaagat gatcagaggt aaaggaatga taaacctcat cacttagcag
    27721 gtaaatatca tgctctctag caatattgat gagctcctct aaataaggct tggtcatata
    27781 ggcacctgtt gggttgttgg cattgttgat catgatcatt tttgtgttgg gacgaatcat
    27841 ggcacctagc tcattaaggt ctggcagcca agcctgctcc tctctgatct gccaataatc
    27901 aacctccact ccaagagaag ctggaatatc atatagctgc tgatagctag gatagtgagc
    27961 aatcacatga tcacctgctt caagcagtgc ataaataacc aaaaaattgg cacctgttgc
    28021 cccattggtt tgcaagatat ttctagcttt ctgctgctga taaagccctg ccactgcctg
    28081 cttaaagtca ggagagcctt ctatccagcc atagtctaat ggcttttgat gcagctgctg
    28141 gtaaaaggct tgaggctgct cctgtgttaa gtcaaagagc tcctcaagcg ttaatgaagc
    28201 aatagatgag ccagcaatat cgtatacagc acgtttttca tgctgattta gccactcttc
    28261 tacaccaaat accggtagtt tcataagatc accttatttc ttgcgtaata tttattacaa
    28321 tatcgcataa aaatacaatt gtcaaatcaa aaactatcct ttttttgata agaatcatgt
    28381 cctatctaac agttagtcct gattggtctc gcatgaaagg ctactaaata gagcaaaaat
    28441 cacataaaaa gactcccaac ccaccaatca gcgggattag gagcctgata gctcgtatca
    28501 attcattgat ttcagatcag agtgactatc atcactctac tatgagccaa tgactaggct
    28561 aggcggacaa cttctagctg tgatccaccc attaatacca agtatttttc gatccttgca
    28621 atcccgtagg attggctcag agcctcggca tataggtcca tttgctgctg atagcgctgc
    28681 ttcagctcag ctgactgctg atagcgatct gtcttatagt caaaaagaac aatacgatcc
    28741 tcaaaaagca ggtagccatc aataatacca cgcactacgt actgctcctg acttaggctg
    28801 tcttttttca gcatcgcaaa aggagcctcg cggtgtaggc gctggtgatg ctcttgcagg
    28861 agctgcccca attcagttgt cgcaaaaaaa gaggttacct tttcaatgtc aagccttgcc
    28921 ttgacctctg cgtcagctga gacaagctgt aaggtctgtt caatatcacc agcagtaacc
    28981 tgatcagaca ttggaatacg ctgcatgagc tcatgcaggc ttgagccgac ctggctaggc
    29041 tcaacagcct ttttcttaga aaaatcagga agctcaaagg tcttgggcct atgataaggc
    29101 tgatctatga tatcaacacc atcagtatcc attagaggct cataaagggt tttaagctga
    29161 ctgggggttc tcaccgtcgg cagctcaatg gccgcctgat agcttgcatt gagctctgac
    29221 accttatcca gcatgtctaa ggcacgcgca atgtcctctg tttgacggtt atccttgaga
    29281 tcatctgctt gcagcagccc tgagggcctt agctgaccaa cagcttctgg tgttaagtca
    29341 ctgtcatcaa caaatcgcac atcaataaac aagtcctcct tgctaaatgt tgctgctatc
    29401 gctagtagcc agtcttgaaa gctcagcaat ctttctcgac tagctaaggc taagcgtcct
    29461 tcggagctat tgtcggctgt tttttcctgt accttttcct tgctagcctt accaatgagg
    29521 tatacctttt tttctgctcg cgtcatggcc acatacaaga gacgcatttg ctctgataag
    29581 gtcgccaagc gtagctgctg cttattgagc tggtaaggaa gagtttccat cgtaaccttg
    29641 agcgacgcca atttttcttc tcttagaagc tcctttacat tggcgacata tttgataccg
    29701 attccctcat ctctatttag aatgattggc gcctgtaggt cagccatcgc aaagcgcttg
    29761 tcgcaattca aaatgaacac gtaatgaaat tcaagtccct ttgatttatg aattgtcatg
    29821 aggttaacag catgcttagg cctttcgacc tcaacatctg ccaaatcatt ttgcgtctcc
    29881 agcaccttat caatcatgcc aataaagcgt gagagtccct tgtagcctga ttgctcaaat
    29941 tggtcagccc gtatagcaag ggcgtaaagg tttgcctgag cctgctctgc ctttggctgg
    30001 cttgctacaa agtcaaagta aaagcgatcg ttaaaaatct tccaaatcag ctcataaagc
    30061 gaatgaagct ttgcaaattg acgccagtct ctcaaggtcc catcaaaatc agccagcttt
    30121 gtcatcagct cctgaccgat cagctctggg tgctcgcctt gtcctctcaa gctattgcta
    30181 agcttgtcat agaaggcttg aggctgcttt tgtgagctgc cttgcagtga gattcttgcc
    30241 agctgatcct catcaaagga aaacattggc gagcgcatta aggccactag ggcataatca
    30301 ttcaaaggat tgttgatgct tcttagcgta tccagcatga ccatcacctc aactgatttg
    30361 aggtaatttt cttggccacc atcagcaacg agaggaatgc catactgatt aaagacctga
    30421 aaaatagtgt catttcgtgt gcgtgacgaa acaagcaggg taatatcttc aaaagcaacc
    30481 ttctcctcgt tatagagcct gatgatttcc ttagccacta agatgacctc acctgcggag
    30541 ataccatcgt tagctaaggc ttcctcggtg ccttcttgaa cttgatcggt gtcatagagc
    30601 agcaattggg ctcgattgtt aggatatggc tgtctttgtc cctcactgcc tgctaccagc
    30661 tggtgcttgt catcataggt aatctctcct aaagactcgt ccataaggcg gctaaagaca
    30721 gcgttggtga catttaggac ctctgactga ctgcggaaat tttcctttag taaaatcagc
    30781 ttgccatgct cgggattgct ttgataatcc ttaaactttt gattgaagat ttgaggatct
    30841 gcttgcctaa agcgatagat ggattgcttg atatccccaa ccataaaacg attatggcca
    30901 ttagacagca gctctaatag gcgctcctgc atgtgattgt tatcttggta ttcatcaacc
    30961 atgacctcat gataatgacc ttggtaagct tggcgaatat ctggagcctg ttgtaaaatc
    31021 tcaatggcaa aatgagctat atctgaaaat tcaaaggcat tttcttgcat ttttgcagcc
    31081 aaataagcct ctgaaaagct gatcacaaag gcttgcagca cctccaaaag tggtaagctc
    31141 tcctgttgat aagcaaggat agtctccaag tgcctaaatc ttaccagctg ctcctgtagc
    31201 gatttgaaaa tagggtattt gtgaccggct acagttatat cagctcctga aggaagtaaa
    31261 gctgttagct cctgtgctag ctgacctagt cgcgctttac cgtaaaggct gtcaaaatgc
    31321 aaagcccact catataagct gtcaatcatt ttgaggtgct tagtgtattt ggcagttagc
    31381 ttgccagcct tggttgtttg agcgtaaccc tccatgtctg tgaggtctcg cagctgatca
    31441 gcagtgtcct gcatacaggc taagagagca tctacagctt ggtctggaat atctgtaaag
    31501 ctggtatagg tcttagaccc tcgtaaaaag acctctgcca accaactgct aggattggca
    31561 gttgattgac tgaaggcata aatgctatca acaatctctc taaaggctga gctatcctta
    31621 cgacgtccag aaaaattctg caccagctgt ataaaggctt tattgtcagt ctgcgacata
    31681 tagtcttcaa aaacctgacg aaagacctcg cgctttaaaa tgtcctgctc tgccttatcc
    31741 tgtatgatac gaaaatgcgg tgaaatccct aaaacataac catgctggtg aaccaatttc
    31801 tgagcaaagg catccatcgt accaatatca gcctgtgata aagcctgcaa ttggtcatta
    31861 aggtaggcct tgagctgata atcctgagtc tctgctatag ctgtgtgcag ctttttttca
    31921 attctctcta ttagctcagt agctgctttt acggtaaagg tcgaaataaa taagcaatca
    31981 accggaatac ctcttagaat cttatccaaa atgcgctcaa ccataacaaa ggtcttacct
    32041 gagccagcag atgctgatac taagatattt tgtccactgc tataaatagc ctcaatctgc
    32101 tgcgctgtcc gcttgtgcgt cttatctgat aaggcctcct cctgctgcaa acgagcaata
    32161 gcctctggcg ttagaaagcc ttcatcaatc ctcatgcttt atctcctcat tcattcgtgt
    32221 caagaaagcc tgtctccttt cttttgtcgg taggacgact aggcgtctcg cgtaccctag
    32281 atctaaatcc gcctcaaagc gcgtgatggc cttgagctgg tcaccctgaa cagacttgcc
    32341 gtctgcggta taagggttta ttaggaaatg ccctgtttta atctgcttca ccgcagacaa
    32401 atatagctgc tcattataag ccagcagggt ttctagctca tcagtctcat aaagtgtgtt
    32461 gttaaggtga tagctgccat tagccagata ttccttggct tgggctaaaa aaatgccctt
    32521 ataggttaac tccttgtaag ccgcagctac tagctgatca tcaagtgcct taaagtcaga
    32581 cagacttagc cttggctctt gcatgtgcag gtacatggcg ccaaacaggc cctgcccctt
    32641 attctttagg gcagcaagat aggtcacaag ctgaggactc aagccattgt aaaaggcaac
    32701 aatgtcaaat acccttgcac tggatttgta gtccacaatg cccagcctac catcagctag
    32761 ctggtcaata cggtcaataa cccctcgaat aagcacttgc tgacccagcg ctagctcaaa
    32821 ggcctcctct tgcttggtta tctgcaggcc ttgattaagg tctaagacag aggctgttga
    32881 gtaagcaatc ccctttagga cctctaagct atatcgccct tcagcatcag cctgataaac
    32941 ctgctgaaaa gcgctttgct gattaactgc tgcaatagct gcgcctagct tttggtcaaa
    33001 ggcagcatta gacctatcct tggttaccaa ctcaaaaata cggtgcaggt attgaccatg
    33061 aatgcgagca tctgggtgaa tagactctgg ctcttgcagc cctaggacat atttcaagaa
    33121 atacttgtat tgattgttat aaaatacagt caaggccgat gaagacagat tcaagggctg
    33181 ctgacttgaa aagcgggtct caataacctc aggtgctact ggcttagtag tcaaatgatg
    33241 ctcaaaagct ggaagactta gctgctcatc ggctagccta cgtttcaaat aacgaagggc
    33301 aaccgtccaa aagtttctgt cctcactggt catgtcatct gcaattccct gccgattaat
    33361 agccaccaag cgagacaaga gagccttata attgccaata tctgccgctg agtgtgacaa
    33421 acggttcttt cctttttcaa tgactggaac accaagggca attagctcct tcaggtaagg
    33481 agagacatca tctgagctat tcgttaagct tgtaggcagg cttaacacca gctcctgcgt
    33541 cgctgcatta aacagggaaa gtgctgtttg gtgatttttc ttgatatttt caaagctcgg
    33601 cacatcaagg cgctggtaag aggcagtctg ctcattgatg cttgcccttt cctgatcaga
    33661 gatcaggctg gtgttttttg tctgcttagg aaaatgggag cgactcaggc caatcgcaaa
    33721 cacaaagggc ttggaatgcg gctccaccag atcataggat ttgatagaca caacatctaa
    33781 ggtcgcaggc actgtccgat aatgtgctgt ctgcatgccc atcttgatca gagctagaca
    33841 gtctgcaagg gtcatttttt cctgaccaaa cacctgataa aaggtctcta aaatgcctgt
    33901 gaaggctttc caaacctcct cgtccttttc cctatcagtc tcccttctac tgcctgctag
    33961 tgcctcaaaa ttatcagcca gctgaatggt cttaaaaaag gtcattagct tatcaagtag
    34021 ggaagcccct agctgctttt gactcttaaa gagctgctgg agaggagtca ccacagcaag
    34081 tcgcagctga ttcaaaagag gcaaaggata ctgacgtgag gaatttaggg taaagggtct
    34141 tgaaaatttg gtgaagcctt gaatatcagc aaagaccaag tattgctcaa gctgatccag
    34201 ctctccctct tgaaagcgcc caaagagtcc tgattttagt aagttgacaa tatcctcacg
    34261 tcgccaattg tatctgcggc ctctttctaa ggattcgaca aattgaacca aggggtgagc
    34321 agacatcggc tcttgcttgc cgatataata agggatctca aatttctcaa aaataggacc
    34381 aatttgcagc tgataagacg ccacatcacc taaaaggaca agcatatcct tatagcgata
    34441 accctgatag agcttctcac gaatagcctt tgcaacatgc tcaagctcct ctttttgatt
    34501 gagcgcttgc cagatcacaa ccttgctctt gtccttggca ctgagctgcc aatcaagctt
    34561 tgaatagtca tgattggctt caagaagctg tgttaggcga gaaaatgaca catcaaagac
    34621 cttttctgac gttgtgtaga tcggcttggt ttgaaattgc tgtgccagct gttggataaa
    34681 cgcaaggctc gcctcgtaga gatttccctt ggtaaaggct agtcgataag ccttttgact
    34741 gatataggct ccaataacga tttcttcaca ggcttcgttt aagagcgcta gcagctgctc
    34801 ctcctcagct gaaaagcggg taaagccatc aatcactaat acggtctgcc ttagctcgtc
    34861 atctaggctc ttgcttttga tagcctcagc aagctgagcc agcctacttg actggtcgta
    34921 atctccttgt gcaatcagct gctcagcctt ggtcataatc gtgatcaggt cctcttgctt
    34981 ttctggtcta tcaagcgtcg ttaagtcaaa ggctgtcaga ttagctgctt gcaattcctt
    35041 atatagctca actaactggg caataaaggc ctgatctgtc cgtagccggt gaaaaacctt
    35101 tagctcatct tcttgcagct gcatgagcac acgataaaaa atcatggcta agccattatc
    35161 atctaacgct tgtcgattag ctgccttagc taaggtaaaa taacgcgcca tctgctcaaa
    35221 gcgggtcacc gtaatagcaa aggaaccctg ctctggcaat aaggctagga cagaacgttc
    35281 cttttcaaag gatagagagt taggagcaat ataaaagaca cgatagccct tatcagcata
    35341 agctcttgcc tctttgacta aaatctctgt catggaatag ctaatctctg tgtatagtaa
    35401 tttcataaaa ctccttttat ttggacctga tacaacgtct atgcctccat tataacaaat
    35461 cagccttgct tttcccattg ttaatgatct ttcaaacgcc acaagaagcg ctcacagcat
    35521 gaaaaaagcc taccatttca catctgctgc tttgcgcaag aaatgataag gctttgtctt
    35581 gtataggctc aaaaaacaga ctaagagctc ctagttaagc tgccctgtgc ttgtctcttg
    35641 tgatctgtcc ccaggcattc tttttacgct gataaccaat aaagctgctc accttgataa
    35701 gggttaatac cgtatgaaga acaaggcatt ggtagatggc agcatagatt acccaagcca
    35761 tatcaaaaag agtaatgcta ctattgtttt gcaaataaac cctatttaaa aacgatgtca
    35821 acgcaataag cacacaatag caaatataga gcagcatcag tgacacaaaa aaggttgtgt
    35881 ttaattgatg gcatagcaaa gacagcacaa tgataataac accaaatgcc tcaataaaag
    35941 gagataaaag ctcaaacaaa agatacagca cataggaaat gagtaccgtc gctttaaacc
    36001 gacagcttac aaaaaactgg agatactttt tcaagcattg atacagtcct aaaaaccaac
    36061 gacgcctttg ccgacacaaa tccttcaagc gactgggcgc ttggctccag caaatagcgt
    36121 ctgtttcata gccaatacga taaggaatct tgttgttatg gcagaaaaaa tgtaatttca
    36181 tcaccagctc catatcttct cccagagtcc cagtgtcata accatcaaca gcaatcgcaa
    36241 gctctttttt aaacagtcca aacgctcctg atatgattaa attcccagca gcctggtcta
    36301 ataaaacacg agctccaaaa aaggcacaat catactcaat tgcctgcgca cacgaaataa
    36361 gctgacgcgg caaatggtag tctacgatcc tcccagctgc caatgctact ccctgcgaaa
    36421 ccttgaccat gcccccaaca gcaatgacag acggatcctt tgcagcagtc tttgcaatac
    36481 gcttaagcga atcctcctgt agcatcgaat cagcgtccat gcacaataaa taatcgtatt
    36541 gagcagcgtt aatcccaaga ttgaggctat ctcctttgcc gccatttgcc ttttcaagca
    36601 gggtcagctt gatatgcttg agctgctttt ggcttacagc ctttagaggg cgtgttggga
    36661 tccgctgatt aatcgaacaa gtcaccgctt ctaaatgaaa ctgctccttc aagagcttgg
    36721 cggtatgatc tgttgaccca tcatcaatga caataatctc atagcagtca taatcaagca
    36781 tcagcaagga ctccactgtt tcgataatgg ttagctcttc attataggcc ggaaccaaaa
    36841 tagacactgg cggtaaagaa acatcaccac caacaggcgc ttgctgtcgc ctttcataaa
    36901 ggtgaatagt cccaacaatt aaggatagca gtaaaaagct cgcataggca atcaaaaacg
    36961 ctaaaaaaag atattgggag tatttcaata ctaaaaacag tagctgcact atcattctcc
    37021 tttaacatgc aatcacttgt gcttaccatt cgccttacaa aagcgtctca aggtctgctt
    37081 catcaaatac ccgatattaa aggcaaggat cgctaagcaa acgattatat aaaaaaacaa
    37141 caggtaataa atcatcttat cttctcctct tttcctgcca gacagcctgc acctgctgat
    37201 aggaggtctt taaaacttct cttacccttg gacgctccca gctcaacagt ggatactcta
    37261 ccattgcaat gacctttgat tcctttagcg gtgcaaaacc aatagctatt gcttcaatgg
    37321 ctaattcctc aacaccatag tgctcaaaat aatcatcgtg tattttgttt gaagctggat
    37381 cagaaaaatt gagcagctgc cagggaatcc taagctcaat cagacgctcg ccaaaagaaa
    37441 tatcggtctg cgaatcaaaa tgagccgagc ctcgtttgcc attgccctgt tttaattggc
    37501 cggtagggta gcgcttcagt cctctttttg caatcggaac ctgatcaatg gctgcaaaaa
    37561 taccatcatt tctcaccacc atatcaacca tagtaaatct tggcgtatgc ttgttagggg
    37621 gaaagacata aaagtccttt ccattaatct gcctaaggta attggcatca gtagcatggt
    37681 agcgctcctg caccaagagg cgactgcctt tgtggtcatc aacaacaagg gcaaaatcag
    37741 caaagcgatc aaaccgagcg ctaaagcctt caataaccct gctgcctgtt ttgggcgtaa
    37801 tgtctaaggg aatgagccac tgtctttgta agggctgctt ttttgtcgat tcaatagcaa
    37861 tatagaggta tttttcgtcc tgatcaacga ggagctgctg cccatttttc ttgtaggtta
    37921 gagctctaga ccactcatct gctgcctttt gcccatcaat agcatgcgtc cttggagcat
    37981 gctcaaaggt taagagacca taaccttgag ccttagactg aacatcaccc caaagaaagc
    38041 tttgatgttt attggttgca aaggaggtat tccagctcct agcagtccaa tcgtcctgcc
    38101 agctatggat cgttgcacca cagcagccag acgcaataaa ggctgtgtaa tctgccatca
    38161 agcgctcgcc ttgatccttt tctgtcaaag ggctggaagt cgatatcatt tggtccacac
    38221 ctctggctgt cgaatagcca tagcccgtca caaccactgg gacacgatga tagctcgtca
    38281 gtagcttgac gtatccctga tataagggca tgcgcttaat atccccaaca agcctatcag
    38341 taagccctag acggtcaaat agcagataat ccctataagc cgagtgacaa tccaagagct
    38401 tataggaagc aaaaagaccg gccttaacct tagcgctggg cttaatattt tcaatcgtca
    38461 gttgaacata ttttgctgcc tgagaggcaa agggatcctg atagacaaag ggatctgatt
    38521 gaggcgtatt tgaaaagctc accaagtgct gccagccata tttgcggctc tcgtatgacg
    38581 tgatttcctc catgatttca gccagtatag cctcaaaccg attggcctga ggtgtcgttg
    38641 cataatacct tcccttaaag cctacaggct tggcgtgatt ctgatgattg gtataggcta
    38701 tcgtcccact gtaccaatca tcaccaacaa tatagccgag tagccattta ctcatatcct
    38761 gatcataatg ctgaagccct aaatccgaat gccagatccg ttttctccca tgaatcacat
    38821 caacactagc cctagcttcc cttaacagag tgcctaaata agccttatct aaggcgctga
    38881 tagaagaatt gtcatgataa gcatctattc taaagccctg taataggtac agaggatgac
    38941 ttgctctgtc attgtagcgt ctcaaagcat ggtaaaaagt gacgggcata ataaccctta
    39001 ccctgatcgt atttgcaccc atagctgcta tttgcttgaa ccacctatag taggttttct
    39061 catcaacgct aaggtctcgt cgacgatagc ctgctatgga actctccaca tcaacaccct
    39121 tgatgagata aggagatccc ttttgatcat atatgcgctt gtccttggtg taaaagactg
    39181 tccgaatagc tgactggtta gagaccggca ggtacaagcg accatcaata tcacaacaat
    39241 aatagctcaa gccaatcaca gacaagagca aaccaacaaa gattaaatat ttcttcatca
    39301 ctacctactc caataatgta ttggtatttt tagacggtgc actgtactga tagagcgtct
    39361 caatatgctt atccagccat cgcccacgac gtctaataaa gtcctttagt tgcttaacag
    39421 aggcctcata gctactgtag ttacgactgg ctggcacaag gtaattagtg gcatcgcttc
    39481 ttgatggcac tgtaaacaca tagccccact tatgataatt gcgctgaata gccggaccta
    39541 aaaaagcaac cgtagcatca atatacttga tcaaataatc cgttgataaa acattctgtc
    39601 ggagctgatg ataccttgtg accaccagct taacaaagct aggatccttt agcagcatgc
    39661 aaaaccaagg agcatctgat agggtaaagt ccgcctcatc ataaggagcc tcaatctgat
    39721 tatcaaaggc gttgttaaaa tcccagacca ccagcttgag cttatcgcgc aaatccttat
    39781 aaagataggt tgaaaacttc ccagcatcaa tatttctaaa gaattcattg ataataaaat
    39841 agtctgcaaa ggactcttgg tccagataat cagtgtattg ctttaaatca taagaatata
    39901 ggagcttttc gatatgactg atatcctttt caataaactg cttttgctta ggcgtcagac
    39961 ggtgcaggct tgggtattta atgtctaaag aggacagacc tgcttgattc gtataggata
    40021 cgtaatgatc aagagcctgc ttagccttgt gtcttctatc ccaaacaagg atataaggcg
    40081 ttttatcaga ttttctatca cttttttcga tgtttaccct atgccgcccc tgctcaatac
    40141 tctccacagc caaatacaga ccacaatact gatgatccac cactaactcg caatacctga
    40201 cgttaggtgc ataggtcatg atctcaccgg caatattgta gctaagataa tttcggacta
    40261 gggtccgatc taaaaaagga ccatgcagca cccactcaga ctccttggac atgccagcca
    40321 gcgagactgc ctttggctta gctcttttat tgataaacct tagctttaag gatttcttgt
    40381 caaaatgacg tgacgaattg cccctataag caatcaatgc tgtcaaggac aagcgcggag
    40441 actcagacag gctgtgctct ctatctagct gatcacgaag cgagaccgtc gttttaatgg
    40501 ttttttgccg ctttgtctct ccctcgtatt ccctttgctc tggaatctgc tgatgatgag
    40561 tgtcaatgct aataatcggc aaatgagagc taaactcccc agtgcttctg gagctctttt
    40621 tgaccgtctg caaatggtga tgaatacgct ttgcagaggt cttaggaaaa ccgataccac
    40681 aaatagcagc tagcaagaga cacaccagca caatcacata aatcgtcttt tctttcattt
    40741 acgtcaacca gttatgtcat cgctttgact aacaatatta aaataatcaa ctcgccccag
    40801 ctgataaaca gcctcagtta acggattagc ctgctgatag gtgctgtcat aatcctttct
    40861 tgacagctca aagatcatct caatatcatc agacgtggtg tttttcacgc tctggatcgc
    40921 cttacccgaa aagtagttaa acactaaccg ctccagctca atttccattt gcttatcaca
    40981 gcgaacaatc aacaacagtc tattgtcatt tctgacagct cccataagca acaaaagcat
    41041 aaagatcacg ctgctaccag ttgcagcgac agtataatca ccaacaccac agcaaatccc
    41101 aaccacaatc gtccaaaaaa tatagactgt atctctagag tctttgattg ctgtccgaaa
    41161 acgcacaacc gacagcgcac cgaccatacc aagagacaaa gcaacattat ttccgataac
    41221 tgtcatgacg gttgctgtta agaccgtcaa ggtcatcaac gaaacattaa acttcttgct
    41281 ataggcagtc ccagtgtggg tataggcata tgacatataa atcacaatac ttaacaaggc
    41341 tgcagcaaca atatgcagca aaacatcttg aaagctcaag gtcccacgct gttcaaagac
    41401 atgtcttaat aattgtttca tcttaatatc tctcctaaaa acgataatgc ttgctgatag
    41461 ctctccccat gcaatacttg cttgcactta gctcgctacc attaacagac tccaaaagct
    41521 ttttgatata agacaacaaa aagccattat acttgacctc caagatgacc aaatagggat
    41581 ctagcaggta attctgaggc agatgatctg aaaaaatatc agcattggtc tcagacccga
    41641 taatatgatg atcaaaggta atgcgaatat tgttttcctt tgccacaaat gccttgcgct
    41701 ggtattcgat cactgttttt ggctgataga gctgcattga catgcgacta tagcattcag
    41761 cagcaaagcg atcaggataa gtcagcaata tagacttgtc tcccttaatc aacaattgag
    41821 cgtctgctct ggtcaacctc agagatcgct ttttttgatt gctcccttgc ttttgcttca
    41881 tctccaactt agcaaatgag ctctgactac cgtaattgcg caggcgaatt tttcgcctaa
    41941 gctcaatacc gtcctctttt tcctgccagt caacgtcctc caaagaatca aaatacaagg
    42001 atcgaatcac atatccctca ctagagctat gagcatctag acgcaagagc ttggaaaatt
    42061 catgcgataa gcgataataa tcctcaatgg taatcaaata ctttttttct tgacgcaata
    42121 cctcattcac gccagtgtcc tcctttttcg tctgtaagca atgccttaac accaagctgc
    42181 ctgtaacagc agccaacaaa cctgtctcat aaataagtca gggcaaataa ggtgattgtt
    42241 ggctctacaa gagtcaatca cctgccaaaa tagtaaatcc tgccatctgt tgaaataata
    42301 taaaccagct gatcgtcttg attgcaagac aggcgctttt gtgactgatc tagctgtctg
    42361 ctgctaatat cagttgcatt agcctccttg agcatggcct gcttgagctg ttgctggatt
    42421 tttctggctt gcagctcaga aatctcaaag ctgccattaa ccttttgagc cttgtgcttg
    42481 tagaccagtg ccacatggtc tttagctgtt gtcctagcag tcgacaggag cccttctttg
    42541 ttgagctgag tatgctctcc tacatcaatg gcaacatagt catagggtgc ccgtatccgg
    42601 tgcgctgtta gtattgagga caaaatccct gtcacaaggc agatgcttat cgtagccact
    42661 atcatctgct gccgctgctt acgaatgaac cttgaaaaag cacagacctc cgcctgatat
    42721 tcctgaagct cttcttcaac cttactgtaa tcctgtctaa gatcagccaa gtcagtctga
    42781 cagtccttgc agcttgtcag atgagcctca acaaccgctc tactataatc actcaacgta
    42841 tcatctacat ataatggcaa caaatcctgg atcaactcac aatcatactt catagccata
    42901 ctcctctcgt aattgtcttt taatatgttt tcttgcccta aagacaagaa ccttggcaga
    42961 ggatactgtg atgccaatat ccttagctat tttttcatag gaatctcccg aataaatcct
    43021 cgccagaaag acagcctgca ttttctctgg aagattaaaa ataatcgtta gtgtaatctc
    43081 taacagctcc cttcttgcta tcttatcaag tggttcatca tgccctttag catcaacgat
    43141 ttctaagctt tccatcgaca tattctcata ttttttcttt ttaatttctg taaagaaggt
    43201 gttctttgca atggtaaata accatgtttt gattgaacta tccccactaa atttagcaat
    43261 attacgataa gcctttagaa aagtctcttg agtaatatca tctgataaac tattttgata
    43321 acagcacagc ttatttacaa acctataaac atcatcttta tattctaaat atatgtcctc
    43381 aaattccaac agcttgtctc ctctcaatac acccttaacc attagaccgt ccaatctgcc
    43441 aaaagttaca gattaattta atttttagta taagctgtca tcaagtcaga taaatagtaa
    43501 tgatctatca tcttattatt gactcaaacg acaaattata ttgcatttta gtataagctg
    43561 tcatcaagtc aggtaaataa caaggacata tcatctaaca tttgatccag acaaaaaaga
    43621 cctgattctg taatatacag aaccaagtct ttctcaatag acattgacta gatgattgat
    43681 ttatagcgac atagctagat aggctatgac ttaccgtctt ttggatttgg agacaagccc
    43741 gccaagacct gccaagatac cactgccagc aagagccaat aaagcatcta gctgactagt
    43801 gcctgtttta gggagagtct tagctgagaa ctgagaaacc tctccagcag tctgagcagc
    43861 aactaatttc tcctgatgat gggctgcttg atcagtcatt gcacctaaag tccccttatc
    43921 agactgggac gccctaagac ggataatggt agctgttaag cctgatagct tgaccccgtc
    43981 cttggttagc acaaccccct caggacttgc cagcgcctcg gtgcctgctt gcttggcatc
    44041 gacgataacc tcaccagcaa gaagagcctg aaactcacca gttagcctaa tggtacggtc
    44101 attgctatca gcattgacaa agacagcata aacatcacca ttgcttgctg ttgtctgata
    44161 agcaatcacc aaatcctgtg ccttgatccc atgctcattt ggaacagtga tcagcttgac
    44221 cttctggtct atctcagcct tacttgccaa gcgaaaggca tctgtcgaac ggcgcagcgc
    44281 aatcaatccc ttagtaaagg cctgacttgt cgtgctttca gggtagcgct ctgtatccgt
    44341 tgcctttgcc cagtcaaaat gattaatggc atctgtcgaa tcataggaat catgaataaa
    44401 gtatgggtat tcaaatggtg ttccgtcctc attgaccaag aggtgtgatt tatttggcac
    44461 cttgtcatca gcgaccttgc ccttataggc ttcgtcctta aattgctttg tacgaccata
    44521 ttcctgacca gcatgtagga aaggggtgcc ttgagaggtt agcaccaaga ggttccctag
    44581 gcgcaagcga cgatgaatct ctgccgcatt tgctgcaaca gacggatcct ttttaataga
    44641 ctgggcgata atatcaaaca aggtcaggtt atcatgtgca gcgatatact gaatcacatc
    44701 acccggatca tcagccaaaa agttagtcgg ctgagccttg atattatgaa aaatggtcat
    44761 gatatcccta gcaccgcccg taataaaggc tggagagcct tcatttggaa agcctgattt
    44821 gagctgattg cgaaaatcat ctgagaagga ggcaacggta tctgtctgtg acatccagct
    44881 ttggtccgca ggctgctcag gcatgtgctc atcaccctga taggtgaccc agccctcacc
    44941 aagcatgatg atattcggat taagtgcctt agctgctaaa aaggcttttt caatagctgc
    45001 tgcatcatgg tcccccatca tgtcaaaacg aaaaccatca accttatact catccaccag
    45061 ataagtaatc gaatccacca aaacacgacg actcatgtaa tgcgttgtcc caagtcgtcc
    45121 accaccaaat gaggtcctag cagtgccatc agcattcata aagtgataat aattcggctc
    45181 caggtcctca aaaatatcaa cattagctgt atgattgtag accacatcaa ggataacccc
    45241 cataccacgc ttatggattt cattaacaag ctgcttaaat tcctcaatgc gcttagctgg
    45301 gtcggttgga tcagtcgaat acataccagt caaggcaaaa tagctttgtg gatcatagcc
    45361 ccagttgtaa ttattatcac ttgagctgta ggtcagcata cgctccttgt tggccaattc
    45421 gttgacaaaa taatagctca tcacaggcag cagttgaaca tgcgtaatac caagctcctt
    45481 gagataatcc aacttttcaa caaaggcagc aaaagtccca aattgagcct ttagatcatt
    45541 agcaatcgcc tgatctgagg taaaatcacg aacatgtgcc tcatagataa tggcgtcctc
    45601 acgcttatga aagcccttaa tatcagcaaa ggccagctcc ttatccccaa tagcagcagg
    45661 atcaacaatg gccgccttag ccaccttata ggacgggtct gtcttagcaa gctcgctgtt
    45721 ccatgccgct aacgatttgg cataagggtc cagcacaagg acagacttgc catttctagt
    45781 aatctcataa tgatagaaat agcctctata atctgaaatc ccaagtccgc tatctgctga
    45841 tagagtgatt gaccactctc ccttatcacc ctttgctaga gcgagattac caatcacctt
    45901 ggtctgatca gccttatcat acaaaacaag tgacacctta tcagcacttg gtgaccaaat
    45961 cgtcagatca accttagcac ctgcttctct cacacgcgct cctagctcac cgtcataagc
    46021 atacaggcta tccttgtatt gccaatttgg cctagcctgg aagctctcat gatgaaaggt
    46081 caccgtataa gtggccactg cttgactaaa atcacctgtg atgacagcct tatgagtctt
    46141 ttcatctaag gtgatatcag taatagcaac tgcttcctta ctgtcagtgc tgatttttaa
    46201 ttcttttaaa aggctttcct tatccacatc tgctagagtc gtaaagctcg cctcaatact
    46261 gcttgggctg acctgctgag caccgattaa tctaactgta ttaacaaaat aagggttcgt
    46321 ataaatggtt ggatcctcgt ctttcaagaa aatttgggtg tgattcttta aatctttaaa
    46381 aatataatca ttgggctgaa ttttaacagc gtcacctgtc tgacgctcat ctagcaagag
    46441 aaagcctagc tcattggtat cagctagctt gacatctata taagcaccat atcgaccgac
    46501 ctgcttaaaa tcaataccat ctggccaagc gccctgctga ctagtcattg acgcatcagc
    46561 acttccccaa agccagagcg atttgttgtc ataatggcca tcactgcgat aataattgat
    46621 acggatatag ccctgagcca gcggccgata gtaagacagc tcctggccat caatccagac
    46681 ctcattcatc ttagggctga gaaggtctat ggttcgatcg cccgtcagat tgtctccctt
    46741 agtgttattg atcaaaaagc taaccttatt ggcttgattg gctgaaagct taacgtccat
    46801 gtaatagcca tagtcatctg tcttcgctag actaaaattg gtagccccag tcggccagcc
    46861 tcccagctga tcagatggtg tctcaacatc gtcccacacc caaagaccaa gcgaggatag
    46921 gtcttgagct ggcagggtct tgaaatgcag ccgcaaggtc tgctccgcta tcggctcctc
    46981 tgagcttgta gcttctggtg tctctagaga gctgtctgtc gtaacagaca ctatcgatga
    47041 tgaaggctga gactggtctg tagtttcctc atgcgcctga tcctctacaa gaggtacagc
    47101 tactggctga acttccttga cagtatcagc attgacagca gctgacacct tagtcacatc
    47161 agaaatacca gcaatatcac taatgtcagt agcttctggt agctcatttg agccttggtc
    47221 agcagcctct gacttgacca tgaccgcacc atcagcaggc tcaacactcg tcagactctc
    47281 agctgctgct gtgatctgcc cactagctgt ccccaaagaa aaagcggttg caatagctac
    47341 cgaagccact ccaagcttaa gcttacgaat gccaaataat tgacgctctt caaacagcgc
    47401 ttgattttcc cttaaccttt tcatcattcc tccgtcctta tcctgatagt tattaacacc
    47461 ttaagtatac aaaagaaatc acaatagtgc aatcgttttc tttattgaaa acaatgatat
    47521 ttatgaacaa attagacaag aatcaacgca agcgatttcc ttactgataa atacctgctc
    47581 ccctcactaa gaccagccca ctgcaaagca gaaaagtagc ctaaagagcc ttagtaacag
    47641 ataaatgagc ttaatgttgc ttcatcaact agctggctgc aaccgttttg ctctgatgtg
    47701 gtaacgtctt gtcatcatga ctaagcttga caaaaaacgc tgttagttac ataatcaacg
    47761 gtgcttggta gccttccatt actcctttga ttgttatacc ctaatgatac acaaaacctc
    47821 agtttttata gtagaatatt acactttgtt ttgacaaaga tgtttaatct tgctaaaata
    47881 aacttatcaa tgagggagta ccaatgatga cattcgaatt cacatcgtta ttcgatttac
    47941 aaactgcttt tccaacagag caggcttgca taaatcattt agaaaatatc acttggggtg
    48001 acgtggtgat cagccctttt gacgctacct caaaggtcta taaatgcaag ggaaataaat
    48061 accgttgcaa gaatacaggg aagtatttca ctgtcaaaac aggtactctt tttgataata
    48121 ctaagattaa gctacaaaaa tggtttatgg caatctggct tgtgacttct cacaagagag
    48181 gaatctcctc agtgcaatta tcaaaagaga ttgcagtgac acaaaaaaca gcatggttca
    48241 tgttacagcg tattcgtaaa tgctttggct ctgaaaactg agatccactt ggtgacgtcg
    48301 ttgaagtaga taaaactgat attgatggta aaaataagaa ccaccatgat cctaagaagg
    48361 caaaaacgtt caagaaccat ccttctctga aagataagtc ggcagttatt ggaatggtgc
    48421 aacaaaaaag taaggccaac gctcatacaa tactcgtgat tactctgata gtcggcgttt
    48481 tatcttttat cagctaatgc tgatatgcga acaacttata aggagctgat caatggttaa
    48541 acatgcaaaa actaacctac actttgaatt agaaagatct atctctcgca aagttgatag
    48601 taaattgata gcctatcaag tcagtctttc agatggcttt tatgacaaat acaccaaatt
    48661 atgggataaa acctattcat ttgattttgt catcaaccat cgtgcgtttt atgctcagtt
    48721 gaccaaaaga tgtgtttacg atgtcctttt gcaaactttg gaaaaaatca gtagaaaagc
    48781 cattgcaaag caactagcag agcttgaagc cttggttgat gtttcggaaa gtaaggaaga
    48841 ctttcagata tttttcgaga aaaaatacaa actatcattt cctgatttga agaattgtgt
    48901 ttatccaaag aaaaaggaac tttccgattt tgatcaaaac ctctggatag ctctacatta
    48961 taaccctaga aaggagaggg atacataatg acaacatggt atgattacat ggtaagagcc
    49021 agcgaacact ctggaagtga tggagacctc tggtttcgtt acctttacaa ggttatcaaa
    49081 gacaaagaaa ccaaactaac tactgatgat gtggagcagt tattaaaaaa tccgaatcta
    49141 actccttttc agaaggtaac tctgcaagat gctttaacag aaggtacgca tacaagagag
    49201 catgttttac aggcaaaccg taaaagtcag ccaaaggata ttttgaaact ctttagagag
    49261 ggaaactatg gataaaaaaa tcttattcaa agctctgaat acagaactag ctaaagaaaa
    49321 tattagcctt gacattatct gtgtcggtgg ttttgtcctt gaatattaca atctgcgagg
    49381 aacacaagat atcgatgcct tttatcaaga aggtgttaac atcaggcaga tgatcaaaaa
    49441 ggtgggagat gagtttggcg ttaatgaacc tgatgagctt tggcttaata attcagttgc
    49501 caatcttaat agaataccac ctaaaacgat ttgtgagaca gtatttcact attctaacct
    49561 aattgtcctt gtcccaccct tgtcttatat tcttggaatg aagctagaaa gcggacgaga
    49621 tagggataga caagatgccg gagacattat taagctagct aatatccgtt cccctaaaaa
    49681 acttatcaat acacttgaag agtatgattt tcaacctgat atttcaatga ttttagaagt
    49741 ctttgaaata gcttatggca tggaatggtt agcaaactat atgaccgaac acccagaaga
    49801 atttaggcat tattaaaaga cgatttctgt ttggaagtcg ccttttttga tgtttttgaa
    49861 aacaccttga gattagtcta aactaatctc cataagcaaa aaacagctta gccccgtctg
    49921 ggagtaagct gtttttgctg taatgtatga gataattagg ctaacatcaa tcattacata
    49981 aagggaataa agggttaatg tttcttgcgt ttgcgtgata ctacagctac gcctagactt
    50041 gccaatacgg caagggctgc tgctgtaaag aatggagctg ttgcttctcc tgttgacgga
    50101 agcttgtgtt ccattgcttt aggtaccgct ggtttatctc ctttctgtgc ttctggttta
    50161 ggcattggtt tagcctctgg cttaacttcc ggtttagttt ctggcttagg cattggtttt
    50221 ggt
//
LOCUS       DARYVE010000007        49710 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYVE010000007 DARYVE010000000
VERSION     DARYVE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49710
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            110..637
                     /locus_tag="TVW25_000339"
     CDS             110..637
                     /locus_tag="TVW25_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1378011.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TVW25_000340"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TVW25_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1378012.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TVW25_000341"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TVW25_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1378013.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TVW25_000342"
     CDS             2207..2839
                     /locus_tag="TVW25_000342"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1378014.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TVW25_000343"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TVW25_000343"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1378015.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TVW25_000344"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TVW25_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1378016.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TVW25_000345"
     CDS             3914..4657
                     /locus_tag="TVW25_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1378017.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TVW25_000346"
     CDS             4767..5867
                     /locus_tag="TVW25_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1378018.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TVW25_000347"
     CDS             6223..6930
                     /locus_tag="TVW25_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1378019.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TVW25_000348"
     CDS             7071..7787
                     /locus_tag="TVW25_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1378020.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TVW25_000349"
     CDS             8009..8854
                     /locus_tag="TVW25_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1378021.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TVW25_000350"
     CDS             9226..10071
                     /locus_tag="TVW25_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1378022.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TVW25_000351"
     CDS             10149..11519
                     /locus_tag="TVW25_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1378023.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TVW25_000352"
     CDS             11512..12576
                     /locus_tag="TVW25_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1378024.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TVW25_000353"
     CDS             12577..13269
                     /locus_tag="TVW25_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378025.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVW25_000354"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVW25_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1378026.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TVW25_000355"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TVW25_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1378027.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TVW25_000356"
     CDS             complement(16695..17369)
                     /locus_tag="TVW25_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1378028.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TVW25_000357"
     CDS             complement(17379..18755)
                     /locus_tag="TVW25_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1378029.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TVW25_000358"
     CDS             complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TVW25_000358"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1378030.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKNHCKRL"
     gene            20126..20683
                     /locus_tag="TVW25_000359"
     CDS             20126..20683
                     /locus_tag="TVW25_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1378031.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20720..21613
                     /gene="htpX"
                     /locus_tag="TVW25_000360"
     CDS             20720..21613
                     /gene="htpX"
                     /locus_tag="TVW25_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1378032.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21901..22434
                     /locus_tag="TVW25_000361"
     CDS             21901..22434
                     /locus_tag="TVW25_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1378033.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22619..23305
                     /gene="covR"
                     /locus_tag="TVW25_000362"
                     /gene_synonym="csrR"
     CDS             22619..23305
                     /gene="covR"
                     /locus_tag="TVW25_000362"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1378034.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23309..24799
                     /locus_tag="TVW25_000363"
     CDS             23309..24799
                     /locus_tag="TVW25_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1378035.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24990..25484
                     /gene="nrdR"
                     /locus_tag="TVW25_000364"
     CDS             24990..25484
                     /gene="nrdR"
                     /locus_tag="TVW25_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1378036.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25468..26631
                     /locus_tag="TVW25_000365"
     CDS             25468..26631
                     /locus_tag="TVW25_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1378037.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26632..27540
                     /gene="dnaI"
                     /locus_tag="TVW25_000366"
     CDS             26632..27540
                     /gene="dnaI"
                     /locus_tag="TVW25_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1378038.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27590..28900
                     /gene="der"
                     /locus_tag="TVW25_000367"
     CDS             27590..28900
                     /gene="der"
                     /locus_tag="TVW25_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1378039.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29241..32333
                     /locus_tag="TVW25_000368"
     CDS             29241..32333
                     /locus_tag="TVW25_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1378040.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32537..33130
                     /locus_tag="TVW25_000369"
     CDS             32537..33130
                     /locus_tag="TVW25_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378041.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33174..34505
                     /locus_tag="TVW25_000370"
     CDS             33174..34505
                     /locus_tag="TVW25_000370"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1378042.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34553..35035
                     /locus_tag="TVW25_000371"
     CDS             34553..35035
                     /locus_tag="TVW25_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378043.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35144..36718
                     /gene="mltG"
                     /locus_tag="TVW25_000372"
     CDS             35144..36718
                     /gene="mltG"
                     /locus_tag="TVW25_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1378044.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36791..37273
                     /gene="greA"
                     /locus_tag="TVW25_000373"
     CDS             36791..37273
                     /gene="greA"
                     /locus_tag="TVW25_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1378045.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TVW25_000374"
     CDS             complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TVW25_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1378046.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38517..38795)
                     /locus_tag="TVW25_000375"
     CDS             complement(38517..38795)
                     /locus_tag="TVW25_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1378047.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
     gene            39088..39825
                     /locus_tag="TVW25_000376"
     CDS             39088..39825
                     /locus_tag="TVW25_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1378048.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            39864..40364
                     /locus_tag="TVW25_000377"
     CDS             39864..40364
                     /locus_tag="TVW25_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1378049.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            40383..41072
                     /locus_tag="TVW25_000378"
     CDS             40383..41072
                     /locus_tag="TVW25_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1378050.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            41466..41708
                     /locus_tag="TVW25_000379"
     CDS             41466..41708
                     /locus_tag="TVW25_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1378051.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            41888..42682
                     /gene="racE"
                     /locus_tag="TVW25_000380"
     CDS             41888..42682
                     /gene="racE"
                     /locus_tag="TVW25_000380"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1378052.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            42679..43668
                     /locus_tag="TVW25_000381"
     CDS             42679..43668
                     /locus_tag="TVW25_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1378053.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            43644..44165
                     /locus_tag="TVW25_000382"
     CDS             43644..44165
                     /locus_tag="TVW25_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1378054.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            44162..44623
                     /locus_tag="TVW25_000383"
     CDS             44162..44623
                     /locus_tag="TVW25_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1378055.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            44620..45366
                     /gene="xerD"
                     /locus_tag="TVW25_000384"
     CDS             44620..45366
                     /gene="xerD"
                     /locus_tag="TVW25_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1378056.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            45366..46073
                     /locus_tag="TVW25_000385"
     CDS             45366..46073
                     /locus_tag="TVW25_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1378057.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            46070..46609
                     /locus_tag="TVW25_000386"
     CDS             46070..46609
                     /locus_tag="TVW25_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1378058.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            46846..47568
                     /locus_tag="TVW25_000387"
     CDS             46846..47568
                     /locus_tag="TVW25_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1378059.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            47565..47843
                     /gene="yidD"
                     /locus_tag="TVW25_000388"
     CDS             47565..47843
                     /gene="yidD"
                     /locus_tag="TVW25_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1378060.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            48002..48550
                     /locus_tag="TVW25_000389"
     CDS             48002..48550
                     /locus_tag="TVW25_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1378061.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
     gene            48929..49360
                     /locus_tag="TVW25_000390"
     CDS             48929..49360
                     /locus_tag="TVW25_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378062.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            49361..49651
                     /locus_tag="TVW25_000391"
     CDS             49361..49651
                     /locus_tag="TVW25_000391"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378063.1"
                     /translation="MITDKNYNWLAGKVYDVDANKVTIPVRKNTDILNRYVKVLEAED
                     NPDNGMQFTVSKSNRNVLALNYKLRSFYDSKKESHHFIRNGSNFSNGRYIYV"
BASE COUNT        14382 a         9188 c        11694 g        14446 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt tattaggaat accggctttt cgagggtact
    19321 tgtttggcgt ttcctttttc ttttcgacaa gagtgatata gcggccatct ccattaggaa
    19381 gttggtaggg ctggtgatca agcaccttag caaaaagtag ctgaagtgcc tttttagctt
    19441 cttctaattc ttggtccgct gcttgtgcct ttaaagcaat cagttttccc ttgattttta
    19501 aaaaaggaat ggtcaactca gacagaatct gcatgcgggc aacagctcta gcagttacca
    19561 aatcaaattg gccacgaaat tgcttgtctt gtccaaaatc ctctgcccta ccatgataga
    19621 aatgtactcc ctctaatcct agctctttag caaggagctg aagaaaatgt atgcgcttat
    19681 tgagagaatc aataatggta acatcaagct ttggaaacat aattttcata ggaatgcttg
    19741 ggaagcctgc tccagcccca atatctaaca gcctgagagg ctcatttgga atatatccct
    19801 gtaaaagcgg agcaacagag tcataaaagt gcttgagata gacttcattt tcttcagtga
    19861 tggctgttaa gttgatctta cggttccaat caaccaaaag cttaaaataa gtgtcgaatt
    19921 gttctttttg atgatttgtc agagcaaatc ctgcttgctc caggacaagg taaaaggctt
    19981 ggggtgtcat atatatcctc tgtttttaat taattgctac tattttagca taaaatagca
    20041 gaaaactgct gaaaagtccc ttcaatactt gctattaaac tgaaaattgc tataattgag
    20101 acacaaagat taaaggagaa ttacaatgcc aatgttttta gtaatagtag cccttatcgg
    20161 tgtgctggtt gtttggctga tggttagcta taatggcctg gttaaagctc gtatgcatac
    20221 aaaagaagct tggagtcaga ttgacgtgca gctaaagcgt cgcaatgact tgattccaaa
    20281 ccttgttgag acggtcaaag gctatgctaa tcatgaagag aaaaccttag aaaagattac
    20341 tagtcttaga tcacgtgtgg ctgatgctac tacaccgcag gccacaatgg cagcctccaa
    20401 tgaattgagc aagcaggtca ctagcctctt tgcagttgca gagagctatc cagacttaaa
    20461 ggccaatagt aatttcctaa aattgcaaga ggaattaacc aatacagaaa ataaaatttc
    20521 ttattcgcgt caattattta atacaacaac atcgcattat aaccttaagc tagaaagctt
    20581 tccgagcaat cttgtggcta aattgtttgg cttcaagcca agtgagtttt tacaggttcc
    20641 tgaagctgaa aaagaggttc caaaggtaga ctttaccgtc tagtctaatg cggctaatca
    20701 aggtcagaag aggacatcaa tgctttatca acaaatttca caaaataaac gacgaactgt
    20761 tatcctgctt tttgcctttt ttgtcttact ggtagtgatt ggcgctgctg ctgggtattt
    20821 actggctgac agctaccagc tgggggctgc ttttgctctg attattggtg ctatttatgc
    20881 ctttagcatg atttttcagt caaccagcct cgttatggga atgaataagg ctaaggaaat
    20941 cacagtaaac gatgctcctg atttctttca tattgttgag gatatggctc tggttgctca
    21001 gattccaatg ccaagagtat ttatcattga tgatccctca ctaaacgcct ttgccacagg
    21061 ctccagccct caaaatgcag ctgttgcggc aaccactggt ctactaaagg tgatgaatcg
    21121 tgaggagtta gaagcagtga ttgggcatga agtcagccat attcgtaatt atgatattcg
    21181 gatatccact attgcagttg ctttagctag tgctgtcaca ctgatttcca gcattggggg
    21241 gcgtatgatg tggtatagcg gtggcaggag acgtgataac gatcgcaacg ataatggctt
    21301 tggcgctatt atgctgattt tctcaatctt gtcactgatc ttggctcctc ttgcggcctc
    21361 tctggttcaa ttagccattt ctcgtcaaag agagtatctg gcagatgcca gctctgtcgc
    21421 gttaaccaga aatccagagg gcatgattag ggctctacaa aagctaagca attcacagcc
    21481 tatgactcat ccagtagatg atgctagcgc agccttatac atcaatgagc ctagaaaaaa
    21541 agaaaagctt agcgctttat ttagtaccca tccgccgatt gaagatagaa ttgaacgctt
    21601 gaagcatatg tgagagcttg agactagctc agctctcatt tttactagcc ataatgttca
    21661 gaaaacatca ttaattaatt gttttgaccc ggacattttt taagactttt atggaaattt
    21721 gggctatttt cataggggtt ttatggttaa acatttgatt gttggcttgt caatacttat
    21781 ttgtatccag acttaatgtt aaaaaaagtt atgaatttgt cataaagcta ttgacaaatt
    21841 cttgatatca tagtaaaaat agattagagt tttattagga agtgttttat aggagaaagc
    21901 atgttatctg tttcagatat tagaaagcga ccggaaggca ttcgctttga gagagagtac
    21961 gatgttaagg aagcgctgct tatacgtgat ccgcaggtta tagatattaa taacgtcaga
    22021 gcttcgggga gagctcagtt tgatgacggc ttgtatctat tagagtatca gctgggctat
    22081 cagattaccc tgccctcgag ccgttccatg gcgcctgttg tcttagatga gatgcagacg
    22141 gttcaggagc tgtttatcga ggaagcagat gtggcaagta agcaggaaat ggttgatgaa
    22201 aaccttgtct tagtcttatc agaggatcag cttgaccttg aagagagtat tattgacaat
    22261 attttgttgg cgattccctt gcaggtattg acagaggctg aaaaggagtc acaaatcttg
    22321 ccgacagggg aggattgggc agtcttaact gaggagcaat accaggccca gcagaaggaa
    22381 aaagcaaaag acaacagtcc ttttgcgggc ttacagggtc tttttgatga gtaaaaataa
    22441 aaattaaaga tgtctgtatt ttttatttga aaaaagaaca gttgtctggt atactttata
    22501 aatatacggc atattagtca ttttgatgac taaatagcaa tacttgatta atacaaaatg
    22561 gatgaatctt gtacatagct gataaggggc tgtgatacag gaagtaagga ttggtgtaat
    22621 gacaaagaaa attttaatta tcgaagatga aaagaatctt gcaagatttg tttcgcttga
    22681 gctacagcat gagggttacg aggtaaccgt cgaggttaat ggtcgtgagg gcttggagac
    22741 agccctagag aaggactttg acttaatcct tcttgatttg atgcttcctg agatggacgg
    22801 atttgaagtg acacgtcgat tgcaaacaga aaaaacgact tacatcatga tgatgactgc
    22861 gcgtgactct attatggacg ttgtagctgg cttggatcgt ggtgctgacg attacatcgt
    22921 gaagccattt gccattgagg aattgctggc gcgtattcgt gctatcttcc gtcgtcagga
    22981 cattgagtca gagaaaaaga ctcctagtca aggcgtttac cgcgacttag tcttaaaccc
    23041 tcaaaaccgc tctgtcaatc gcggtgatga cgagatttca ctgactaagc gtgaatatga
    23101 cctgcttaat attttgatga caaacatgaa tcgtgtcatg actcgtgagg agctcttgtc
    23161 taacgtttgg aaatatgacg aggctgttga aactaacgtt gttgatgttt atattcgtta
    23221 ccttcgtggg aagatcgata tccctgggaa agagtcttac attcaaactg ttcgtggaat
    23281 gggttatgtg attcgcgaga aataattgat ggcaaagcag aaaaaatata agaaaacgtt
    23341 accaaaacgt ttatcgaatc ttttgttcgt tctcttcttt tgcattttct ctgcctttac
    23401 cctactcgct tatatttcaa caaactactt tttgttgaaa cgagaaaagc aaactatttt
    23461 tcaggctgtt aacattgtta gagttcgtct ctctgaggtg gactctaatt ttacgttaga
    23521 gaatttagca gaggttctct ataaaaatga cagaacgcat ttaaagattg atgacgcaaa
    23581 tggtagtcgt attatcagaa gtgaacgaaa tatcaccaac acgctcaatg ccaatgagga
    23641 tatctatgtc tacaatgttg ataagcaaat gatcttcaca acagatgacg aagaggcctc
    23701 gccaggctta aatggaacta ttggtaaggt aaccaaggac cacattgagg agcaatacaa
    23761 gggcttttca atgactcaga aggtctactc taataagaca gggaagtttg taggctatgt
    23821 tcaggttttc catgacttgg aaaactacta catgatcaga gcacgcctct tcttttggct
    23881 tttggtggtt gagctctttg gggttggtct ggcgtatttc attatcttaa ttgtcacacg
    23941 caacttcttg aagcctctga acaatcttca tgatgtgatg cggacaattt ccaaaaatcc
    24001 agataatctg atgctgcgct cgggtatttc ctcgggtgat gaaattgagg aattgtccgt
    24061 tatttttgat aaaatgcttg ataagattga gacgcataca cgattgcaat caagatttat
    24121 tagtgacgtc agtcatgagc tgcgcacgcc agttgccatt atcaaggggc atattggatt
    24181 attgcagcgc tggggcaagg acgatagtgc tattttagat gaaagcctca ctgcagctgc
    24241 gcaagaggtt gaccgaatgg ctattatgat caatgacatg cttgatatga tccgagtaca
    24301 ggggtccttt gaagggcatc aaaatgatac aactgtttta gagagctcta ttgagaccgt
    24361 tgttggtaat tttagggtcc tgcgtgagga ttttgatttt acctggtact ctgaaaatca
    24421 aagaacccta gccaagattt ataaaaatca ttttgagcag gctctgatga ttttgataga
    24481 taatgcggtc aagtattcta ggaaggaaaa gaaaatcgtc atagaattag cggttaatgc
    24541 tagcaatgaa gctgtggtta aggtcaaaga cagaggtgag gggatctcag aagaggatat
    24601 taagcatatt tttgagcgct tctaccgcac cgataggtcc agaaatcgaa ccagcaccca
    24661 agcaggtctt gggattggct tatccatttt aaagcaaatt gttgatggct atcatttaca
    24721 tatggaggtt gagagtgagc taaataaagg gtcggtcttt attttgcgga ttcccttagc
    24781 tgatcatcaa ggctcatagc tgtatacctg cctgagtatc tagtagatgc tcaggctttt
    24841 gactgttcta atgtgtggtg tgatgatgag gtgtttatca gggaaggagg gctcttggag
    24901 gtaaacctga gtgcttgtct attcttttgt tatccctaaa attatggtaa aatagggtat
    24961 tagattaacg atagaattgg ggtgtttgcg tgcgttgtcc gaaatgtaac tataataagt
    25021 caagtgttgt tgatagtaga caggcagaag atggcaatac gattcgtcgc cgcagagaat
    25081 gcgaaagctg tcacacgcgc tttacaacct ttgagcgctt agaagagctt ccattactag
    25141 tgatcaaaaa ggacgggact agggagcagt tttcaagaga taaaatctta aatggtgttg
    25201 ttcaaagtgc ccaaaagcgt ccggtgtcaa gtactgacat tgaaaatctc atttctcgca
    25261 ttgagcagaa ggttcgtaca gcctatgaaa atgaggtgtc aagtactgtt attggcaatc
    25321 tggtgatgga ggaattagca gagcttgatg agattaccta tgttcgtttt gctagtgtct
    25381 ataaaagctt taaggattta gacgaaatcg aagagctctt acagcagatt actaatcgcg
    25441 ttagaggaaa aaagaagagc agtgtagatg atgaagccta ttgatacctt ttcttatatt
    25501 aagcataatc aggttcaata cgattcaagc agcctgattc agttgtattt tcctattatt
    25561 ggaaatgacg cagtggcagt ttatcagtat ttggttcact tttttgatga tggctcagga
    25621 gcccacaaat ttagtgatat tttaaaccat ctgcagtttg gaatgaagcg cctagaggaa
    25681 gccttggtga tgctgacagc tattgatttg ctggtcttat atcagctgcc agatgcttat
    25741 ttgataaaac tacatcagcc cttgggcagg gaagcctttt taaataaccc aatttatcgt
    25801 aggcttttag agcaaaagat tggagatgta gcggttttgg agttgcaaat ggtgattccg
    25861 aaccaggcta gaaacatctc aaagaccttt tcagatgttt ttggaataga ctctcaggag
    25921 cttaagcagc ctcagccatc aaagataaat tttgatttag atagctttca gcagctaatg
    25981 cggcgtgacg gtcttaggtt tgaggatcat caaaaggacg ttatcagtct ttacagtatt
    26041 tctgagcaat accacctaac ctggtttgac acctatcagc tggctaaggc aacagcagtc
    26101 ggcggcagca ttcgcccaga gcgcatgcta gtcaagaagc agcaagaggg cgctcaaaaa
    26161 acaagtgaat cgttctcacc agctgagcag gttgttctta gagagtctaa gcaggacacg
    26221 cctcttgtct ttttagagaa gatcaaaaaa gctaggcgag ctagagtcac aaaggacgaa
    26281 aaggaattgt tgctgactct agcccgcatg aatttcttgg acgaggtcat caatattatg
    26341 gtattatata ccttcaataa gaccaagtca gctaatcttc acaagactta tctgatgaaa
    26401 atggcaaatg attttgctta ccagcgggtt ttaacagcgg aaactgctat tatcaagaca
    26461 cgcgcctttg gtgagcgtaa gcagcaggca aagtcacagc agtccaatgt gcctaagtgg
    26521 agcaatccgg attatcaaga aaaaacaagt caggaagaac aggcaaagct agagcagttt
    26581 aagcaggctg ccttaaaaag gctggagaac ctaggaaaga gtggtgacta gatggaaaag
    26641 atcgggaaaa tggtagagca tttgggacag gctagtcgtg tagctagtgc tgagctgatt
    26701 gaggctatac ttgctgatca ggaggtggct gagtttatca aggctcacca gctatctcag
    26761 gcagaaataa agctgagttt atcaaagttc aaccagtttt tagttgagcg ccggaaatac
    26821 cagacaggtg atgagaccta tattgctaag ggctatcagc ccattttggt catgaacgag
    26881 ggctatgcag atgtgtctta cctagagaca agagagcttg ttgaagccca aaggcaggca
    26941 gctattgcag atcggattca tttggttagt ctgccaagat cttatcgtag ggtttctttg
    27001 tcagctgttg atgttaacaa tgccagtcgt atgcaggtgt tttcagagct tttggatttt
    27061 gttgagcagt atccagcggc agagcaaaag ggtctctacc tttatggcga tatgggggtc
    27121 gggaaatcct atctgatggc tgctatggca catgaattgt ctgaaaaaaa gggtgtatca
    27181 acaactcttc ttcattttcc tagctttacg attgatgtta aaaatgccat ttcaaatggc
    27241 tctgtcaaag aagagattga tgccatcaag catgtccctg ttttaatttt agatgatatt
    27301 ggtgcagagc aggcgacctc atgggtgcgt gatgaggtgc tacaggttat tttgcagcat
    27361 cgtatgctag aggatttgcc aacctttttc acctctaatt acagctttgc agatttggag
    27421 agaaaatggg caaagatcaa aggaaatgat gagacctggc aggccaagcg tgttatggag
    27481 cgtgtgcgtt atttagcacg tgaatgccat ttagaagggg ttaatcgccg ccagggctag
    27541 ctaaacgcta gctcaagcga tggataatga gataaagaaa aggagaatca tggttttacc
    27601 tacagttgcc attgttggac gtcctaatgt tggaaagtcc acgttattta accgaattgc
    27661 aggagagcgt atttctatag ttgaagacgt cgaaggggtt actcgcgacc gcatttacac
    27721 gactggtgag tggcttaacc gccaattttc attgattgac acaggtggta ttgatgacgt
    27781 tgatgctccc tttatggagc aaatcaagca tcaggctcat attgcgatgg acgaggcaga
    27841 tgttattgtc tttgtggttt ctggtaaaga gggcgttact gatgcagacg aatatgtctc
    27901 taagctcttg tatcgtacca acaagccagt gattttggtt gtcaacaagg tggacaatcc
    27961 agagatgcga aacgatattt atgattttta ttctcttggc ttaggagatt ccttcccggt
    28021 atcatcagtt catggtattg gtacgggtga tgttttagat gctatcattg ataacctgcc
    28081 gatagaagag ccagtagaaa acgacgatgt gattcgcttt agcctaattg gacgtccaaa
    28141 tgttggaaaa tcaagcctca ttaatgcgat cctaggagaa gagcgtgtca ttgccagtcc
    28201 tgttgctggt acgactcgtg atgcgattga tacaagcttt accgatgaat ccggtcaagc
    28261 ctataccatg attgataccg caggaatgcg taagtccggc aaggtctatg aaaatactga
    28321 aaaatactca gtgatgcgtg ccatgcgtgc cattgaccga tcagatattg tgttaatggt
    28381 tattaatgcc gaggagggca ttcgtgacta tgataagcgg attgcaggct ttgcgcatga
    28441 ggcaggtaag ggcatgatta tcgttgttaa taagtgggac accatcgaaa aggataatca
    28501 tacagtagct aggtgggagg ctgatattcg tgatcaattt caatttttga cctacgcccc
    28561 tattatcttt gtttctgccg ttacaaagca gcgcttaaac aggcttcctg agttgattaa
    28621 gcgtatcagt gatagtcaaa gccagcggat ctcgtcagct attttaaacg atgtgattat
    28681 ggatgctatt gcgatcaacc caaccccaac ggataaggga cggcgtctaa agattttcta
    28741 tgctacacag gtttctgtga agccgccaac ctttgttgtt tttgtgaatg aagaagagct
    28801 gatgcacttc tcttatctgc gctttctaga aaaccagatt cgtgctgctt tcacctttga
    28861 agggacacca atcaagctga ttgcgcgcaa tcgcaaataa gcccttttat tactcttgtt
    28921 agtattggaa gcagcgagtg ctgttgatgt gcggtgtcta gaccttgtgt gtcaggactt
    28981 ttgaccgacc aataagcctt accagaaatg agaggctgct atccaaatag agcttaccag
    29041 caagcaaggc gtgccaagca ttgatgtcac atgataatca ttagccctag gctagtgatt
    29101 ttttagtgct ttaaagccta tcagaacagc tatatacagc tactcaaata tgttttaata
    29161 gcctttaaga gagatttttg caggaaatct aagctgaagt ttgttataat caaaggataa
    29221 gcaaaaaggt gggagcagat atggctagat taattccggg gcggattcgc aatcaaggca
    29281 tcgagcttta tgagcaaggc ttggtgaaaa tcatagatga caggactgac cttcttcgag
    29341 cagaggtgga tacttatcag gttcaatatg gtatcaatga tgaggatatt aggtgtcagt
    29401 gtgattattt tgagcgaaag cagtattgcc agcacattgc ggctctagaa tattttctga
    29461 aaaataatca gaagggcaag tcgctctcag agcagcttaa caaccagctg gaaagtaagg
    29521 aggaaactaa aaagctgacc tcctttggta gtcttttttt ggacagtttg cacatgaacg
    29581 aggacgacac gaccaaatat aggcttttag cttctggtgc taaaagtcct ttctcatctg
    29641 attactggtg gagccttaag ataaatcgct tgcccggaga gaaggcttat gttatccgcg
    29701 atatcaaggc ctttattcat ttggtcaaag ttgagggctt ttaccagatt ggaaagaatt
    29761 actttgagtc tctttccata ttgcagtttg atcaggctag tcaggagctg attcgttttc
    29821 tttggcgttt atcaacgcat tcagataagt tagattacga atggctattt cctaaccacg
    29881 ctcgtcatct tcggttaccg gcaggctttt ttgaggaggg cattgacctg ctgacggggc
    29941 tttacgagtt ttcatttgag acctcctctc aaacctattc tcatctttat gttcgacctc
    30001 tggaggcaga ggctggtctc tttcagttta cagttgatgt tcatcgcagc tctattgagc
    30061 tttacattaa ggaaaaaaat atagagtatt ttttcaataa tgaatacctg ctatacatga
    30121 acacctttta ccacctgagc ctgaagcagc aaaaaatggt tcaagctatt cgcagcctgc
    30181 ctattgaggc cgatttggcc aagcacattc attttgatct tgatgatcag gctaagctgg
    30241 cagctagctt gctggaattt cgagagcttg gtcaggtgaa ggctcctaaa agctttgata
    30301 ttagagattt ccaagtgact tttgtctttg atattactga aaaaggtgag ttgacctctc
    30361 agctgatttt tgactatggg agcattcaga tcagtgataa ggcaagctta gaccagctcc
    30421 cctttgctag ccattataaa aaagaaagca gtatttatcg tgccttgaag cgctttgggc
    30481 tttctccgca gttttttgct aagaaagcct tgactgaccc caaggactgg tatcgctttt
    30541 ttacagaagc tgttccttat tttgaaagtc taggtagggt tcagctttcc tctaagctcc
    30601 aagatcagcg cttaatggaa agccctcagc ttacagtcaa acgtgaggga ggtcttttag
    30661 atatttcctt tgatttttca acggtttgtc agactgatat tgaaaaggct ttggccactt
    30721 tgtttagtga tcgctcttat tttgtcaatc agtcaggcaa gctggtcgtt tttgatgaag
    30781 agacacaaaa aatcagccgt agcttacagg aactaagagc taagcagctg gcaaatggtc
    30841 acctccagct agaaggaata gctgccaccc agctgtctca tctattttcg gatctgtctt
    30901 ctgttcattt ttctgaggag ctagagaccc taatcaagga cctgcagcac ccggatcgct
    30961 ttgagctggg agagctggcc gttaaggcca aggtgagaga ttatcagctg cagggcatca
    31021 aatggctctc tgtgcttgat aagtatggct ttggtggtat cttggcagat gatatgggct
    31081 tgggcaagac actgcaaatc attgcctttt tatcaagcag gctaaccgag acctccaagg
    31141 tgcttatctt ggcaccctct agcttgattt acaattggtt agatgagttt agtaaatttg
    31201 cccctcagat agatgctgct gtatcctacg ggctaaagcc ggcacgagat gctcttattc
    31261 aagaaggaca tcaggtgacg attaccagct attcttcctt taggcaagat ttagaaacct
    31321 atcaggcaaa tgattatgat tatttaatct tagatgaggc gcagatgatt aaaaatgccc
    31381 agaccaagat tgctcagagc ctgcgtgcct ttgacgtgaa gaattgcttt gctttatctg
    31441 gtacgccgat tgaaaataag ctgcttgaaa tctggtccat ttttcaaatt gttctgccag
    31501 gcctgctgcc atctaaaaaa gcctttttga aaatggaggc cagagacgtt tctcgctata
    31561 ttaagccctt tgtcatgcga cgcaaaaaag aggaggtctt gccagagcta ccagaattaa
    31621 tcgagatgaa ttattacaat gagatgtccg atggtcaaaa agcgatttat ctggcacagc
    31681 taaggcagat gcaggagcgg ctgtctgctg caactgatga tgatattaat cgcagtaagc
    31741 tggaaatcct gtctggtatc acacgtctaa ggcaaatctg tgatactcct agcctgttta
    31801 tggattatca aggaggaagc ggtaagctag acaatctaag aaccttgctg ctgcaaatta
    31861 aagaaaacgg tcatagggct ttgctgtttt cacaatttaa gggcatgctg gctcttgtca
    31921 agcaggaaat ggatcagctt ggcttatcat cttataccat aacaggctca acaccggcca
    31981 atgaccgtca agaaatgaca cgtgccttca ataatggctc aaaggacgcc tttttgattt
    32041 ccttaaaggc cggtggtgtt ggactcaatt taacaggtgc tgatactgtt attttgattg
    32101 atctatggtg gaacccagct gtagaaatgc aggccattag tcgtgctcat cgtattggtc
    32161 aggaggacaa tgtagaggtt taccggttga ttacccgcgg aacaattgag gaaaaaatac
    32221 tggagcttca ggaaaataag cgtcatctga ttaccactgt tttagatggc aaacaaggcc
    32281 tagcaagcat gtctgtcgag gagatcaaag aaatccttgg tcttcagccc tagcatgtat
    32341 ggcttttagc acacgctctt aagcctatca gctaaaggct agtgtctgtt ctctataaca
    32401 aataaggcaa gagaatagag gtgatgagct agtcacatca tttttgcttt gctgcctttc
    32461 tttttaggaa ttactttgaa aaataggatt atttagttta taatagggaa tgctatagga
    32521 aggagagtga gatagaatga caaagcatgc gtttcctctg gttgcagatg gtgagcctat
    32581 tattgagtca gctaggcaga tggctttata tgaaaacgaa gatttgatca caaatattgc
    32641 tggcagctat caagataaac attacgacga catcataaga gaccatcaat ttgctgagaa
    32701 gactcctgtc gtctctaaag gatcccttca tcattctcca gttgtcgatg aagatcatag
    32761 ctacgctcaa aaggccagaa ggcaagcaaa gcaggatgtc aaagaaaaaa gacaggctta
    32821 tattgctaaa aatatggctt atagcccaaa gcaggcaagc aagaaaggtc aaagtggggc
    32881 cttctcttct aaaaaaccag cgacagaatt gagccgtttt acagagaaat taaaccaaga
    32941 gtcttatatt ttagctgagc ttcctcgtca atataaggag ccgcaaaata ccagccaagc
    33001 agctgtcaaa aaaaataatt atgacttttt gaagcgcagc caaatctaca atcatcaaga
    33061 agacagagat catcgtgaaa agaccattgc tcaagagcta aacctgagtc gctttgaaga
    33121 tattaagtaa gctttataca gccttatgtc tgtcaacatt aaaaggagtt aacatgtcaa
    33181 aaacctatca ttttatcgga attaaaggat ctggaatgag tgccttagcc ctgctgctcc
    33241 atcaaatggg gcataaggtt caaggcagtg atgtggagaa gtattatttc acacaaagag
    33301 gcctagagca agcaggcatt accattttgc cctttagcga agataatatt tctccggata
    33361 tggagctgat agcaggtaat gcttttcgtg aggacaacaa tagcgaggtt gcttatgcga
    33421 tgcgtcatca gctgcccttt aaacgctacc atgagttttt aggtgagttt atgaagcagt
    33481 ttactagtct tggtgtagcc ggtgctcatg ggaaaacctc taccacaggc ttgttgtcac
    33541 atgtgctcaa gcacatgacg gctacttctt atttgattgg tgatggtact gggcatgggg
    33601 ctgccgatgc tcgttatttt gtgtttgaat cagatgagta cgagcgtcac tttatgcctt
    33661 atcacccgga atattctatt atcactaata ttgattttga tcaccctgat tattttacag
    33721 gccttgatga tgtgttcaat gcctttaatg actatgctaa gcaggtgaaa aaggctcttt
    33781 ttgtttacgg tgaagatgag gaattaagaa agattagctc tcctgcaccg atttactatt
    33841 atggctttga ggacactgat gatttcgtag cctttgatat cacacgcacg acaaatggct
    33901 cagactttaa ggtaaagcac aagggtcatg ctattggtca gtttcatgtt ccagcctatg
    33961 ggcgtcacaa tattttaaat gctactgcgg tgattgctaa tttatttatt gcaggctttg
    34021 atatgaagct tgttgcagag catctgaaga gcttttcagg ggtgaagcgt cgttttactg
    34081 aaaaggtgat caatgacact attattattg atgactttgc tcatcaccca acagaaatca
    34141 ttgcaacgct tgatgctgct aggcaaaaat accctaataa ggaaatcatc gctatttttc
    34201 agccacacac ctttacaagg accattgctt tgctagatga ctttgcccat gccctaaatg
    34261 aggctgacag tgtttatcta gcgcctatct acggctcagc gcgtgaggtt gataagggtg
    34321 atgtcaaggt ggaggatcta gcggctaggg ttgagcgccc agccaaggtc atctcagttg
    34381 acaatgtatc gccgctgctg gatcatgata atgcagtcta tgtttttatg ggagcaggtg
    34441 atattcagtt gtatgaacgc tcgtttgaag agctgctggc taacttaact aaaaataatc
    34501 aatgattaag cgacctgcct taggcaggtt ttctcgtcgt aaaggaggac ctatgctaat
    34561 tagacatgtg aatcagactg actgggagat tattgctgat atcgaacagg ccaatttttc
    34621 tccccaagag gctgtagcag ccaatgtgat aaaagagcgt gcagagctta tttcggatac
    34681 ctttcttgtg gctgttatcg ccaatcagtt tgtcggctat atcgaaggac ctgtcattgc
    34741 tgagccaagg cttgaggatc acctatttca tggtgtgacc aagaatccag caagaggtgg
    34801 ctatatagcc attaccagtc tttctgttgc tcctggatac caaaagcagg ggattggcac
    34861 agctctctta gctgcaatga aggatttagc agttgcacag gatcggctgg gtatcatact
    34921 tacctgtcat gactatttga ttccttacta tgagatgaat ggttttcaag atcaaggcct
    34981 gtcagcttca aagcatggtg gctctgtttg gtatcaaatg ctatggcagc cataggaagg
    35041 ctattaaagc ttagcatgta ttaagaatta gtaacaaaag ggggatttta ttgcatttat
    35101 agtgcaatta ggatataatg gcggttgatt aagtttagga ggaatggctt tgactgattt
    35161 taaagatgat gagcaaagac gtcagcagca aaaaagcttc aaagaaaaga ttctagccga
    35221 attagaaaaa gcaaatcaga ttagaaaaga aaaagaagaa gagcttttta aaaaggatct
    35281 agaggttcaa gaggctgcta gaagaacagc tcagctttat gcagaatata aaagacaaga
    35341 agcactaagc aataacccca aacaagcgtc tgatatagca gctgcgtcgc aagagacgac
    35401 ctcaacggct tcaacagccc acacctctgc gattaagcta gaagagacag cagtagctac
    35461 tggggatcaa gcattgtcgc caccagagga gcctgcattg agtgaaagcc tgcttaagga
    35521 agaggcaagt gtcgaaggtc agactaagaa gggtggtcca gtgagaagaa aaacaagtaa
    35581 gcgccagcag acagatcgaa tggccaaaaa aatttcgaca gtactgatat cgtcgattgt
    35641 cgctattatt gtggtgattg gcctcgcagg gacagcctat gtgtatagtg cccttaaccc
    35701 tgttgacaaa aatagcgatg actttgttca ggttgaaatc ccagccggct caggcaataa
    35761 gcttattggg cagatccttg aaaaagaggg gctgatcaaa aatagtaccg tctttagctt
    35821 ttacactaag tttaaaaatt tcactaattt tcaaagtggc tactacaacc tacaaaagag
    35881 catgagccta gaagacattg cccaggcctt acaagagggt ggcacagcag agcctacaaa
    35941 gccagtacta ggaaaaattt taattccaga gggctatacc attaagcaaa ttgctaaggc
    36001 catagaaact aatagtaggg caaagaatcg tagcaaggct aaaacaccat ttcactcaaa
    36061 ggatttcttg aatttggtga caagtgatgc ctttattcaa gagatggcta aaaaatatcc
    36121 gaaattgcta ggagatcttc caagcaagga agtagctact tatcagctag aaggctacct
    36181 tttccctgcg acctataatt attataagga aacaacacta aaagaccttg cagaggaaat
    36241 gattgcagcg gcaaatgcaa acctagcgcc ttattatgag gcgattgcag ctagtggcaa
    36301 gacagttaat gaggtgctga ctttggcctc cttagttgaa aaggaaggct ctactgatga
    36361 cgatcggcgt caaattgcca gcgtatttta caatcgctta aataatggca tggccttaca
    36421 gtctaacatt gctatattgt atgcaatggg taaattggga gaaaagacaa ccttagcaga
    36481 ggacgctgct attgacacaa ccattaattc tccttataat gtttatatca atactggctt
    36541 aatgcctggt ccagttgata gtccagggct tgcagctatt gaggcgacta tcaatccagc
    36601 ggcaacagat tacgtttatt ttgtagccga tgtgcgtact ggtgaggttt attatgcaaa
    36661 aacatttgaa gagcactctg caaatgttga aaaatatgtt aacagtcaaa ttcagtaagg
    36721 acaaacatgg tgctttagca tcatgtttgt gtttctgatt cgtcaaaaga aaaaggaaaa
    36781 gagaaagata atggcagaaa agacttatcc aatgacagca gcagaaaaag aacagcttga
    36841 aaaggaatta gaagagctaa aattagttcg tcgtccagag gttgttgagc gcataaaaat
    36901 cgctcgttcg tatggagacc tttctgaaaa ctctgaatac gatgctgcta aagatgagca
    36961 ggcttttgtt gagggacaaa tctcaacctt ggagacaaag attcgctatg ctgagattat
    37021 tgatagcgat gctgttgcca aggacgaggt ggcgattggt aagacagttg ttgtccagga
    37081 ggttggcaca caaacaacag acacttatca tattgtcggt gcggcaggag cagatatttt
    37141 ttctggaaag atttcaaacg agagtccaat tgcacaggcc ttgattggta agaaaacagg
    37201 agataaggtt aagattgagt ctccagcagc tacctatgag gttactatca tcagcgttga
    37261 caaaacacaa taagacttat ctgactatca gtgcagtgtc ctgatagtct ttttagtggc
    37321 ttgcttttta atatcagttg ttgtggtcta ttaaaaagag ctgcacttta gaaagtttta
    37381 actaagatac tttatgacct agtctcatac attaaaaaag cgaacaggtc taattttcgg
    37441 aatccctgaa aattagacct gttcgtttgt tttatcttga gtcagacttt tgtcacagac
    37501 tcttttagct atcttagcga cgcttttttt gtttaccggc gtttcggttt aacttagtcc
    37561 tcttgcttgt gctaagggct tgcttttcag ctgtaacgtc cttgcgtggc tggtgagatt
    37621 tataggcctt aggagggttc tttgcgaact cctctgcaat ttgcttgcgg agccttggtt
    37681 ttaaaaggta ggttgtgatc aattgctgaa tgatactaaa gaaaccacca actagccaat
    37741 acaagcctaa tccggcaggc aggtaaaacg acatgacaat catcataatt ggcatggtgt
    37801 acagcatggc tttcatttgt tcacgttgct cctcagggac tgccatcatt gacagccagg
    37861 attgaacgaa gtataaagcc gcaattacag ctgtaagcaa gacgctgcga tgccccaggt
    37921 caatgcccat aaaggtactt gttgagactc ccttggtaaa ttggaccgca acatacatgg
    37981 cagaaaagaa aggcatttga atcagcagtg gcaaacagcc tataccgcct agcgggttga
    38041 ctccattttc acgctgggcc gccattaatt ctgtttgggc tgccattttt tcttcagtgc
    38101 ttgtagcgtt tttgatgcgt tgattaattg gctcaaaaaa aggctttagg taggccattt
    38161 tttctgattg gtagcttgcc ttccatgatt ggtagagccc aagtggtagg ataatcgttc
    38221 taacaataat agttacaaca atgatggcaa gaccatagcc tagggcggtg ctgttagcaa
    38281 agtaatcaat gagaaaggaa acgggctttc caaggtaatc ccaaatgatg ccctccgggt
    38341 gccccttggc gtctctgccg acacaccctg tcaatgtcag taggaccgat aaggcaagtc
    38401 ctgagaaaag tatgcgattc gttttgagtt tcaatgtgtt tgtcctttaa tttttaatat
    38461 acctaaccat tttactgttt ttttgagaaa ttaacaatag ttctacagta ggatttttaa
    38521 ttgctgatcc taaaatcatg gaaatcctca aagtgagatg gattaacatc aacataggtc
    38581 acctttgccc atttagaagg tccttttctg atttcctgga taaagcgcgt catctttgca
    38641 gggtcactag cctgtgctaa aatctcaaca gtcccatcac tattgttcca cacgcggccg
    38701 taaatatcac caatttccaa agctagtgcg taggttgaat agcgaaagcc aacaccctgc
    38761 accctgcctg aaacgattag tctgaccttt ttcataagtc acctcttttc tttttattat
    38821 agcatagata gcttataaat actaaaagtt gtcatggagc aggcagccaa aggataggca
    38881 aagactgcaa gtgggctatc tgctgaggta aacaataggt cttagtgcag caaggctatg
    38941 tttatggtta gctctccttc ttgtcttcta aaaaggaaag ctaatgggct tacgacacct
    39001 gataagggga gaaagctcct tttaggctga tagccttctg atggttttta tgcaaaagag
    39061 tgaacaattt tgtgatataa taagaccatg attatcacat caaaagcaaa ccatttgatt
    39121 aagcaggcta agaaattact gcaaaaaaag catcgcaagc actcttactt gattgagggc
    39181 tggcacctat ttgaggaggc tcagagatct gggcaggaat tgatacatat ttttgttctg
    39241 gaggaaatgg cagagcgctt atcaggcttt gatcaggttg tcatcgtcag tccagagatt
    39301 ctaaaggagc tgacgagctc tcccaatcca cagggcatta ttgctgaggt taagctttgt
    39361 caacaggcct taccgactag ctatgctgga aaatatttga ttttagagga cattcaggat
    39421 ccaggcaatc tagggacaat cattagaaca gcggacgcag caaagtttga tggggtgttt
    39481 ttgtctgaga agtctgcgga tgtctacaat caaaaaactc tacgctccat gcagggcagt
    39541 cattttcacc tgccgatttg gcgaacggat atttatcagg tcagtcaggt gatgcagcag
    39601 caaaaaatac cagtgctagc aacgaccttg tctcaggatt cgattgatta caaggacctc
    39661 tcagctagga gcagccttgc ccttgtttta ggaaatgaag gtcagggcat tagtcctgag
    39721 atggcagctt tggctgatca gctgattcat attagcatgc ctggacaagc tgaaagctta
    39781 aatgttgcag ttgcagcagg aatcctcatt ttcagcctaa tttaagctag tatggtataa
    39841 taatgatgtg aggtgattag tgtatgcatt atacagaaga tacagaatac atggagcatg
    39901 ttggtcattt gattgctcac cctcgctttc aaaggcttgg agatattgtt cagcatcacc
    39961 attctactcg cttagagcac tctgtcaatg tttcttattc tagctatagg ctggcaaaga
    40021 ggcttggctt agacgccaag agtaccgcac gaggtggctt gctacacgat ttcttttatt
    40081 atgattggcg agtaaccaag tttaacaagg gacacgcttg ggtgcaccct agaattgctg
    40141 ttcgaaatgc taaaaaatta acagcactca acaaaaaaga agaggatatt atcctaaagc
    40201 atatgtgggg agctactatt gcttttcctc gctataagga aagctatatt gttacctttg
    40261 ttgataaata ttgggcggtc aaggaggcca tgacgccgct gcgtcaaaaa tggacgaacc
    40321 gtcgcttcct gcgtcgaaag acgcttcaaa gtcacaatca ttaagtaaaa aaaggagtta
    40381 tgatgaacga taatgttatt tacacacagt ctgacgcagg cttgagccat ttttttgcca
    40441 aggtctatag cctggttggt atgggagttg ggctttctgc ctttgtttct tatttgatgc
    40501 tgtttccatt taggcaaaat ttagtctcga ttgttcttga tcatcctatg gtctattatg
    40561 gggcggctat tgttgagctt gtactggttt ttgttgctag tggtgctgca cgtcgcaata
    40621 caccagcagc tttaccctta tttcttgtct attcagcctt aaatggcttt accttgagct
    40681 tcattattgc agcttatgcg caaacaacgg tgctacaggc ctttatctca tcggcagctg
    40741 ttttctttgc tatgtcactg cttggtgtta aggttaagcg tgatctgtca ggtattcgaa
    40801 aggccatgtt tgcagccttg attgggatta tcgtggctag tctggtaaat ctctttatcg
    40861 gtagtgacct gatgagctat gtgatcagcc ttatttcagt gttgatcttt tctggcttga
    40921 ttgcttcaga caatcagatg atcaagcagg tctaccaagc ctctaacggt caggttggtg
    40981 acggctgggc tgtcgctatg gctcttagct tatacctaga ctttatcaac ctctttatca
    41041 gtctacttcg tctcttggga agaaatgact aatagctatt ttaagcgcag ctgctgattg
    41101 tcacttaatc gctattacga gaaatcagcg aagctgcagg tgttaccttt tgttagaaaa
    41161 gagtggctgc tgctagtaag aaagtagctg ctaggagagc ctgatgagcg tgactgtcaa
    41221 ggaaggccag ttactattgc taccatctag ggaaggtacc aaaaaaagtc aagaagcggg
    41281 cccaagggct cgtttttgtt tgcttgattt gtggtaaagt gcttcaaacc aagcctatat
    41341 ctagtctgat agctcttatc agctgacaac atcatattta caatgcctgt tggtgtagat
    41401 ttgtaaagca tgctcttttt tggtataatg agaggaacaa aaaatcgagg agaatatcta
    41461 tcaatatgtc tacagctatc tggatattat taatcattgt tgctcttaca gccggtcttt
    41521 ttggtgggat ttttattgcc cgcaagcaaa ttgaaaagga aattggagag cacccacgat
    41581 taacgcctga ggccattcgt gaaatgatga gtcaaatggg tcaaaaacca agtgaagcga
    41641 aaattcaaca aacttaccgc aacattgtca agcaatcaaa agccgcaatg actaagggta
    41701 aaaaataggt tacggattag aaatcgtggt ttctaagcaa tagctaagag tgaacagtct
    41761 ttgatgttaa aagcttgttt agagcttgca ttgtcagtta gaggtgtcaa ctgttcaggg
    41821 gttaacaata gactcagttg gctcttacca gctgagtttt ttatgcttca atgaggaaat
    41881 aatcgttatg gacaatagac caattggttt tttagattct ggtgtaggag gcttaactgt
    41941 tgttagtgag ctgatgcgtc agcttcccca tgaaaaaatc atttatattg gtgattcagc
    42001 aagagctcct tatggtccta gacctgctga acaaatcaga gaatatacct gggagttggt
    42061 tcgtttttta ttaacgaaac atgtcaagat gattgtcttt gcttgtaaca ctgcaacagc
    42121 tgttgcttgg gaggaggtca aggaggcttt ggatattcct gttttgggcg ttatcctgcc
    42181 gggcgctagc gcagctatca aggctactag tggaggaaag gttggtgtta ttggcacatc
    42241 aatgactatt tcttcaggca tttaccagga aaagatccag ttgctggctc ccactgttca
    42301 ggtaactagc ctagcctgtc ctagatttgt tcctattgtg gagtccaatg agataagctc
    42361 aagtgtggcc aagaaaattg tctatgaaac cttggctccc ttagttggaa agatagatac
    42421 ccttgttttg ggctgcaccc attatcctct tcttaggacg attatccaaa atgtgctggg
    42481 accacaggtt aaattgattg atagtggggc agagtgtgtg cgtgatattt ctgttctttt
    42541 aaattatttt gagattaatg gcagtcgaga tgatgaacat aggcgtcatc atttttacac
    42601 tacagccggc tcagacagct ttcaagcaat tgcctcagcc tggctaaatc aaacgataga
    42661 tgtggagcat gtgaccttat gagtgataac atttatgaat acaaggataa agacaattgg
    42721 tttattggca agatgacagg ccataattta atggctggct ggggggttaa ccatgagctt
    42781 attgccaaaa tagacgatat gttaggtgcg attgctggtg atgtggattg ggaaagtccg
    42841 gtcggttatg atgtgactgt tattcgttac gcctcccctt ttgccttgat tagctttgtt
    42901 gttggcatga tcaatcagaa agccaatcga gcccttaagg ttgttcggca ctcaggtgcg
    42961 attttagtga ccgaaaacga gcgattgctt gctgtgcata tgccagatga tggcgtccct
    43021 gtggctgact tctttggtca acaggcagat ggctttgggg atacgatttt gattgcgact
    43081 cgaaatgaag gcaagaccaa ggaatttcgc cggctttttg gtgatatggg atatcgcgtt
    43141 gaaaatctca atgattaccc agagcttcca gatgtggcag aaaccggggt cacctttgag
    43201 gaaaatgccc gcctaaaagc agaaaccatt tcaaggctta ctggaaagat ggttctggca
    43261 gatgattcag ggctcaaggt ggatatttta ggtggcttac ctggggtctg gtcagctcgt
    43321 ttttcgggcc ctgatgctac tgatgagact aataatgcta agctattgca tgagctggca
    43381 atggtatttg atcaaaagga tcgctctgct caatttcata cgaccttggt ggttgctgca
    43441 cctggtaaag acagcttggt tgtcgaggct gattggcatg gctatattgc aaccaagcca
    43501 aaaggcgagc atggctttgg ctatgatccc ttgtttatcg ttggggagac tggacgtcat
    43561 gcagcagagc tagctgctga tgaaaaaaac aagctgtctc ataggggaca ggcggtcaag
    43621 aggttaatgg aggtatttcc agcatggcaa gcaaaacaat cattgtgatg agcgattcgc
    43681 atggcgatcg tgaggttgtg gcagctatta aaggccgtta ccttggaaag gttgatgcca
    43741 ttttccataa tggcgattct gagctagaaa gctcagatcc tatttgggag gggattcatg
    43801 ttgtggcagg caactgtgac catgatagcg gctataagga tagcctagtc acctcctttg
    43861 atggcttgac tattgctcaa acacatgggc atttgtatca tattaacttt acttgggata
    43921 ggctagatta ttttgctcag gagactggag cggatatttg tttgtatggg cacttgcaca
    43981 gacctgctgc ttggcaattg ggcaagactg tctttatcaa tcctggctcg gtcgctcagc
    44041 cgcgtggtga ggtgaatgaa aagctgtacg cgcgtgttga atggacagca gcttgcatta
    44101 gggtggatta ctttacctgt cagcataagt cttacccatc actttctaag gaatttaaac
    44161 gatgatagca aaagaatttg aagccttttt aatcagtcat ttggatagct acctgattcc
    44221 agcagaggag ctagccattt ttatcaacac gcataatgct gatcatgtca tgctcttatt
    44281 ggttagcaat ggtttttcac gagttcctgt cattaccaag gaaaagcaat atgtcggaac
    44341 gatcagcatt tctgatataa tgacctatca agccaaaagg cagctaacag actgggagat
    44401 gacgcaaact aatattggcg acatggtcaa tacaaagatt gagaccatca atattacctc
    44461 tagcttgact gaaatcatgc ataaattggt tgattttccc tttttaccag ttgttaatga
    44521 tgacaatcga tttatcggta ttattacgcg taagtccatt ttgaaggcgg ttaatagcct
    44581 tttgcatgac ttcactgatg aatacacaat cacaaaaaaa tgatagcatt tattgaaccc
    44641 tttctagcaa gcaaatctct tgctaataac agccagcaat cctatcgcta tgatttaagg
    44701 cagttttgcc agcaggtcgg acagcgtatt aatcctgaaa ccctagccct ctatcagcaa
    44761 agcttgtctg gccttacggt agcagctaaa aagcgcaagc tttcaacggt caatcagttt
    44821 ttgtactatt tgtaccagca gaaggctttg acagactatt ttaaaatgga cgataggata
    44881 gaagcctctt tttctttgaa gccccagctg acaaggcttg acaccagcgc tttttatgct
    44941 gaaacagcct tcctaaaagg gcagctcatt gcgctgctga ttctggagct gggcttgacg
    45001 ccaagtgaga tagcagggct tcgtcttgct gattttgacc tgggtcttca ggtgctaagg
    45061 ttgcaatctc acagaggcat tcgtgtgatg accttatcaa aggccttgct gccatttttg
    45121 gaaaaggcaa cagaagctca gcagctctac ctctttgatc atgacgccaa gcccttttca
    45181 aggcaatggt tttttaacca gctcagagat tttttagaga gcattggctg tgcggagctt
    45241 tcagcccaga gtctgagaga gcaattcatt ttaaatgaaa aagcagccgg taaatccatc
    45301 attgaggtgg ctcagctgct ggggctaaaa agcccgatca ccttagaaaa atattataag
    45361 atgtaatgga tataaaagta aaagattttg aaggtcctct tgatttactc ttgcacctag
    45421 tgtcaaagta tgaggttgat gtttaccagg tgcctattgt ggaggtcatt gaacaatact
    45481 tggcctatat tgagaccctg caggcgatgc gcttggagct tgctggagag tacatgctga
    45541 tggctagtca gctgatgctc atcaaaagca gacgactgct gccaaagctg gtagacaagg
    45601 agcctgatga ggaggatctt gagcaagagc ttttgggtaa gattgaagaa tatagtcgtt
    45661 tcaaggctct gagtcaggag ttggccagcc agcatgacaa gagggctctg cttttttcca
    45721 agccaaagca ggagcttatc tttgagcagg ccgtcctaca aaaggataaa acagtcatgg
    45781 atttgttttt agctttttca cagttaatgg ctgcaaagca agaggccttt aaatataacc
    45841 atacggttat tgagcgagat gattatcgta ttgaggatat gatggagctt attgaagcta
    45901 ggcttgagct agagcaggag cttactttga cggatttatt gaagcattgt gatcatctca
    45961 atgaggccat taccttgttt ttagcaagcc tagaattaat caaacggcag cttgttggta
    46021 ttgagcagac atcacatttt ggccagattg ttttgcgaaa ggagatccaa tgacctattt
    46081 atctcagctg gaggccttgc tgtttgtcgc aggagaagaa ggactaagcc tacgtcagtt
    46141 ggccagccta ttagagttaa caccgacagc cttacagcag cagctcgaca agctttctca
    46201 gaaatacaaa gaggataagg aatctggcct gtgcttgatt gagtcctcta ggacctataa
    46261 gttagtcacc aaagagtgtc tggctccctt gcttaaagac tatgctaagg ctccaatcaa
    46321 ccaaaccttg tcacgagcaa gcctggaggt tttgtcaatt gttgcctata agcagccgat
    46381 tactcggatt gaaattgacg agattcgtgg tgtcaattca agtggtgccc ttagtaaatt
    46441 agtggccttt ggtttggttc aagaggctgg caaaaaggaa gtgattggtc gaccaaatct
    46501 ttatgcaaca acagattact ttcttgatta tatgggtatc aatcatttag aagagctggt
    46561 tgatatttct tctattgctg ttgaagagca agagacaacc ctgttttaaa ggcaaagagg
    46621 agcttgtctc atttgcagat aggccttatg ccctctacta gaagagataa cagtcctaac
    46681 aaggtatagt gcctgaaaat cctattgtcg ttatggacag cggtcttttt aggcatgcta
    46741 ttaataagag tagacctgtt taagctagtg agcttttacc cataggagag tgactggtct
    46801 gttggagcta tcatcagatt tcctaataag aaagagagaa ggataatgag aattaacaaa
    46861 tacatcgccc atgcaggcct tgctagccgt cgtaaggctg aagagctgat caagcgaggg
    46921 ctggtgaccc taaatggtca ggtgataaca gatttagcaa ctactgttaa atcaggcgac
    46981 cttgttgagg tagaggggat tcctatttac aatgaagaga aggtttatta tctcctcaac
    47041 aagcctcgtg gtgtcatctc aagcgtttca gatgataagg ggcgtcagac agtgattgat
    47101 ttgctgccgc aggttaagga gcgcatttac cctgttggtc gcttggactg ggatacctct
    47161 ggcttattaa ttttgaccaa tgatggtgat tttacagata aaatgattca cccccgtaat
    47221 gaaatcgaca aggtttatct ggctcgtgtc aagggagtgg taactaaaga aagcctgcgt
    47281 cccttaacac gtggtgtcgt tattgatggt aaaaaaacaa agccggctcg ttaccgcatt
    47341 attcgtgttg agcctgataa aaatcgctct attgttgaac taaccattca tgagggccgt
    47401 catcatcagg tcaagaaaat gtttgaagtg gttggacact tggttgataa gctatcaagg
    47461 acacagtttg gcagccttga tgtcagaggc ctaaagcccg gagaagccag aaggctgagc
    47521 aaaaaagaag tcagccagct acatcattta gcgagcacac gaaaatgatc aaagccctac
    47581 tcattgctcc tgtcagagcc tatcagaaat atatttctcc cttatttcct ccttcctgtc
    47641 gttatcagcc gacctgctcg gcctatatga ttacagctat tgaaaagcat ggtgctaagg
    47701 gtgttttgat gggacttacc agactattaa ggtgccaccc ttttgccgct ggcggagaag
    47761 acccggttcc agataccttt tccttaaaaa gacatttcat aacgcatgaa aaaatacagg
    47821 attttgacca aaaaactgat tgacaatagc agttaaagtg ctataatagc agttaagtat
    47881 tcgttggttt aaatcaaacc tgttatgatt taagttagcg agtcaccgtc aaccacattg
    47941 tttgctgagc atgactccgg gcagtgtggt ttttttgatg aaaagagtaa gcgggacaag
    48001 catgaaacaa gaaatcatta atagacaata tagggaaaaa gatagtcaaa accatgtggt
    48061 gctctttcag ccacaaattc cacaaaacac aggaaatatt gctaggacct gtgctgccac
    48121 caacacgcct ttacatatca tcaggcctat gggctttccg attgatgacc gtaagatgaa
    48181 aagagcgggg ctagattatt gggataagct agacattaga ttttatgatc atctagatga
    48241 atttttagca caatgtgatg ggagcttgca tgtgattagc aaatttgctg atagggtata
    48301 ctcagatgaa gcctacaatg atcgtcagtc tcattatttt ttgtttgggc gtgaggatac
    48361 tggtctgcct gagcccttta tgcgtcaata tgctgatagg gcactcagga ttcctatgaa
    48421 tgatgagcat gtcagaagtc tcaatgtctc taatgctgtt tgcatgatcg tctatgaggc
    48481 acttagacag caagccttta agggcttaga gcttagccat acctatgagc atgacaaact
    48541 aaaatcataa taagcatatc gcaaaacatc agttagattg aagaagtatc cgtaggggag
    48601 cttcttcagt ctttttttat tgtattcttt gcttattaac caagcagttg acacgaaaat
    48661 tccaatagat cgtttaaagc caataaaacc attattaggc ttgcattaca ggcaggtatc
    48721 aaagaaagat atagaaaaat ataccagaaa aaaatctcat aaaagtgtca aaatagtaaa
    48781 aaatcgccaa aaatatgtca atattatacc attattatag tataatattt ataatcatat
    48841 tataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ctgcaccacc
    48901 ttatgataaa gcataaagga atataagcat gatagtctac ctaaagcaac acaaaaatta
    48961 ctggaaatta gtcagcatag cagctttaat cattatttta ggaggaatac taacaatgaa
    49021 ttggcttaat ggggataggg acaataaagg cgagaataac tactatcaag tagagaagga
    49081 tttagcaatg gaaattgtta gtgagtttga aggagtaaaa gagattagct ttcttagtcc
    49141 agtacaatcc aaagaaacag ggtattgggg aacaacagct actataaata aaactaatga
    49201 gatatcttat tctttttcga tgactttttc aggaaagctt gatgattatt cttactatta
    49261 cgataaatgt tttaaattag tgaagcgtca caaaaaattg acattaagtc aagtggatct
    49321 aacagatatt gatattaaat attctaaggg agggaaataa atgataactg acaaaaacta
    49381 taactggcta gctggaaaag tatatgatgt tgatgctaat aaagtaacta ttcctgttag
    49441 aaaaaatacg gatattctta atcgttatgt caaagtcctt gaagccgaag acaatcctga
    49501 caacggtatg cagtttacgg tgtcaaagag taataggaat gttctagctt taaattataa
    49561 actaaggagc ttctatgaca gtaaaaaaga aagtcatcat tttattagga atggtagcaa
    49621 ttttagtaat gggaggtata tttatgttta gctataatca gaatcaagcg aaaatgttag
    49681 aacgacaatt taaccatgaa caaaaacgaa
//
LOCUS       DARYVE010000008        49114 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYVE010000008 DARYVE010000000
VERSION     DARYVE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49114
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(235..321)
                     /locus_tag="TVW25_000392"
     tRNA            complement(235..321)
                     /locus_tag="TVW25_000392"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(285..287),aa:Ser,seq:gga)
     gene            complement(381..1016)
                     /gene="trmB"
                     /locus_tag="TVW25_000393"
     CDS             complement(381..1016)
                     /gene="trmB"
                     /locus_tag="TVW25_000393"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1378064.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(1016..1807)
                     /locus_tag="TVW25_000394"
     CDS             complement(1016..1807)
                     /locus_tag="TVW25_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1378065.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(1870..2904)
                     /locus_tag="TVW25_000395"
     CDS             complement(1870..2904)
                     /locus_tag="TVW25_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378066.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(2908..3633)
                     /locus_tag="TVW25_000396"
     CDS             complement(2908..3633)
                     /locus_tag="TVW25_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378067.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4170..4613
                     /locus_tag="TVW25_000397"
     CDS             4170..4613
                     /locus_tag="TVW25_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378068.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5066..5485
                     /locus_tag="TVW25_000398"
     CDS             5066..5485
                     /locus_tag="TVW25_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1378069.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            5482..5778
                     /locus_tag="TVW25_000399"
     CDS             5482..5778
                     /locus_tag="TVW25_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1378070.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(5948..7210)
                     /locus_tag="TVW25_000400"
     CDS             complement(5948..7210)
                     /locus_tag="TVW25_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1378071.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(7211..7738)
                     /locus_tag="TVW25_000401"
     CDS             complement(7211..7738)
                     /locus_tag="TVW25_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378072.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(7731..8174)
                     /gene="tsaE"
                     /locus_tag="TVW25_000402"
     CDS             complement(7731..8174)
                     /gene="tsaE"
                     /locus_tag="TVW25_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1378073.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(8540..10000)
                     /locus_tag="TVW25_000403"
     CDS             complement(8540..10000)
                     /locus_tag="TVW25_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1378074.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10259..11070
                     /locus_tag="TVW25_000404"
                     /pseudo
     CDS             10259..11070
                     /locus_tag="TVW25_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            11422..12414
                     /gene="manX"
                     /locus_tag="TVW25_000405"
     CDS             11422..12414
                     /gene="manX"
                     /locus_tag="TVW25_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1378075.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            12585..13394
                     /locus_tag="TVW25_000406"
     CDS             12585..13394
                     /locus_tag="TVW25_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1378076.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            13410..14321
                     /locus_tag="TVW25_000407"
     CDS             13410..14321
                     /locus_tag="TVW25_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1378077.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            14455..14838
                     /locus_tag="TVW25_000408"
     CDS             14455..14838
                     /locus_tag="TVW25_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1378078.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(15159..16211)
                     /locus_tag="TVW25_000409"
     CDS             complement(15159..16211)
                     /locus_tag="TVW25_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1378079.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            16811..18088
                     /gene="serS"
                     /locus_tag="TVW25_000410"
     CDS             16811..18088
                     /gene="serS"
                     /locus_tag="TVW25_000410"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1378080.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(18320..19090)
                     /locus_tag="TVW25_000411"
     CDS             complement(18320..19090)
                     /locus_tag="TVW25_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1378081.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(19087..19953)
                     /locus_tag="TVW25_000412"
     CDS             complement(19087..19953)
                     /locus_tag="TVW25_000412"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1378082.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(19962..21326)
                     /gene="accC"
                     /locus_tag="TVW25_000413"
     CDS             complement(19962..21326)
                     /gene="accC"
                     /locus_tag="TVW25_000413"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1378083.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(21360..21782)
                     /gene="fabZ"
                     /locus_tag="TVW25_000414"
     CDS             complement(21360..21782)
                     /gene="fabZ"
                     /locus_tag="TVW25_000414"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1378084.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(21779..22252)
                     /locus_tag="TVW25_000415"
     CDS             complement(21779..22252)
                     /locus_tag="TVW25_000415"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1378085.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(22254..23486)
                     /gene="fabF"
                     /locus_tag="TVW25_000416"
     CDS             complement(22254..23486)
                     /gene="fabF"
                     /locus_tag="TVW25_000416"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1378086.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(23502..24236)
                     /gene="fabG"
                     /locus_tag="TVW25_000417"
     CDS             complement(23502..24236)
                     /gene="fabG"
                     /locus_tag="TVW25_000417"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1378087.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(24253..25173)
                     /gene="fabD"
                     /locus_tag="TVW25_000418"
     CDS             complement(24253..25173)
                     /gene="fabD"
                     /locus_tag="TVW25_000418"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1378088.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(25186..26172)
                     /gene="fabK"
                     /locus_tag="TVW25_000419"
     CDS             complement(25186..26172)
                     /gene="fabK"
                     /locus_tag="TVW25_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1378089.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(26367..26591)
                     /locus_tag="TVW25_000420"
     CDS             complement(26367..26591)
                     /locus_tag="TVW25_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1378090.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(26649..27623)
                     /locus_tag="TVW25_000421"
     CDS             complement(26649..27623)
                     /locus_tag="TVW25_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1378091.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(27623..28057)
                     /locus_tag="TVW25_000422"
     CDS             complement(27623..28057)
                     /locus_tag="TVW25_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1378092.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(28137..28928)
                     /locus_tag="TVW25_000423"
     CDS             complement(28137..28928)
                     /locus_tag="TVW25_000423"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1378093.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(29248..30384)
                     /gene="dnaJ"
                     /locus_tag="TVW25_000424"
     CDS             complement(29248..30384)
                     /gene="dnaJ"
                     /locus_tag="TVW25_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1378094.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(30541..32370)
                     /gene="dnaK"
                     /locus_tag="TVW25_000425"
     CDS             complement(30541..32370)
                     /gene="dnaK"
                     /locus_tag="TVW25_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1378095.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(32775..33344)
                     /gene="grpE"
                     /locus_tag="TVW25_000426"
     CDS             complement(32775..33344)
                     /gene="grpE"
                     /locus_tag="TVW25_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1378096.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(33389..34423)
                     /gene="hrcA"
                     /locus_tag="TVW25_000427"
     CDS             complement(33389..34423)
                     /gene="hrcA"
                     /locus_tag="TVW25_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1378097.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(34873..35445)
                     /locus_tag="TVW25_000428"
     CDS             complement(34873..35445)
                     /locus_tag="TVW25_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1378098.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(35442..36185)
                     /locus_tag="TVW25_000429"
     CDS             complement(35442..36185)
                     /locus_tag="TVW25_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1378099.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(36175..36882)
                     /locus_tag="TVW25_000430"
     CDS             complement(36175..36882)
                     /locus_tag="TVW25_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1378100.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(36957..38294)
                     /locus_tag="TVW25_000431"
     CDS             complement(36957..38294)
                     /locus_tag="TVW25_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1378101.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(38309..38575)
                     /locus_tag="TVW25_000432"
     CDS             complement(38309..38575)
                     /locus_tag="TVW25_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1378102.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(38839..39954)
                     /locus_tag="TVW25_000433"
     CDS             complement(38839..39954)
                     /locus_tag="TVW25_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1378103.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            complement(40151..40390)
                     /locus_tag="TVW25_000434"
     CDS             complement(40151..40390)
                     /locus_tag="TVW25_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1378104.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            complement(40441..41385)
                     /locus_tag="TVW25_000435"
     CDS             complement(40441..41385)
                     /locus_tag="TVW25_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1378105.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            complement(41614..43053)
                     /gene="gatB"
                     /locus_tag="TVW25_000436"
     CDS             complement(41614..43053)
                     /gene="gatB"
                     /locus_tag="TVW25_000436"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1378106.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            complement(43053..44519)
                     /gene="gatA"
                     /locus_tag="TVW25_000437"
     CDS             complement(43053..44519)
                     /gene="gatA"
                     /locus_tag="TVW25_000437"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1378107.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            complement(44519..44821)
                     /gene="gatC"
                     /locus_tag="TVW25_000438"
     CDS             complement(44519..44821)
                     /gene="gatC"
                     /locus_tag="TVW25_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1378108.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            complement(45295..45852)
                     /locus_tag="TVW25_000439"
     CDS             complement(45295..45852)
                     /locus_tag="TVW25_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1378109.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            complement(46469..47251)
                     /gene="codY"
                     /locus_tag="TVW25_000440"
     CDS             complement(46469..47251)
                     /gene="codY"
                     /locus_tag="TVW25_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1378110.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            complement(47423..48637)
                     /locus_tag="TVW25_000441"
     CDS             complement(47423..48637)
                     /locus_tag="TVW25_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1378111.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            48924..>49114
                     /locus_tag="TVW25_000442"
     CDS             48924..>49114
                     /locus_tag="TVW25_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1378112.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQ"
BASE COUNT        14178 a        11728 c         9543 g        13665 t
ORIGIN      
        1 ttagtgcttc tcatgataag tcttatggga cttttttgta ctcaaaaagc cctatcattt
       61 ccatactgga taaatccact acagaaatga tagagcctaa aatatatgtt caccaattgg
      121 ataagttaaa agaaaaaaat gaccatcagg tcaaaagcat ttttcaaaat ctcaaatttg
      181 acgggtgaaa aacaggcgaa gactccgaaa cccttgatat accaatagga taaaaggaga
      241 ggaggggatt cgaacccccg agccccgtta aggactacac gctttccaag cgtgcgcact
      301 cggccactat gcgacctctc caagtaaaag gctgatcaac tcaacctcag tagtgtatca
      361 tatttttgtc aaaatagcta ctagaatgtt gcttctaggc ggtaaataat ctgtcccttt
      421 ttagcaaatc tagcctcata ctcagtcatc acatttcctt gataatcact agcatgtaaa
      481 tccagccaga cctgcttgag ggtcataccg tactgtgaaa agctcgctag gctatactca
      541 aataagccac gattatctgt tttaaaatga atttcaccat tttccggcaa aatctgctta
      601 taagtgtcta aaaaggattt gtaggttagt cgacgctttt catgcctgct tttgggccaa
      661 ggatctgaaa aattcaaata catcatatca acctcaccgg catcgaaata attggtcagg
      721 cttgacccat caacccgcaa gagcctaaca ttaggagcct gagaggctag gaccttatct
      781 aaagcatagc ttagcactga tagctgaatg tcaatgccaa tatagttgat ctctgggttt
      841 ttcaacgcca tacctgtgat aaaggctccc ttgcctgagc caacctcaat atggatcgga
      901 tgatcattac caaagacctc acaccagcgc cccttagcag cctccggctc taaaatgaca
      961 tagtgaggat tgttttccaa gtgctcctgc gcaccctttc gttttctaac tcgcattatt
     1021 tctttctaaa catttctcta aattttctaa gagcgtaaat ctcttgattg acatgctcca
     1081 tatctctctt atcaaagcac cttaaaatct gagttagata agagaattga gcataccaaa
     1141 taatcttttg catgacctta tcattatttt tatagccata ataggatagc cagtctgccc
     1201 atcgcgaccg aggaatatag tggcttagca aataagccac atcatacatt cgatctgtta
     1261 ggcgcacaca atcccagtcc accaaaaaaa tcatgccact ggtggtaatc acccagttgc
     1321 tatgcttgat atcaccatgt acaatcgtgg ccacctcaga gcgaaattca ggtaggctgc
     1381 gctttagctc cttgacgata gcctgtaaat aagaattctg ttgaatttgc aaaggtgcat
     1441 tttgctcaaa gtctactaaa aggtcataag gattttcaat tttatagttg agctgaagca
     1501 attgattaac caactgcttg gacttgtgga ggcgcagcag aatatggacg atttgcttac
     1561 tgttcatatc ctctctagtc agagtacgac cattgagcca ctcttgagca ctcatcatat
     1621 cgccattccc catacgcttt gcccaaagca attgtggggc aatctgttcc tttgctaagg
     1681 caggtaggat tggtgttgta ttaagcttga taaagacgct ttcgccattt ggataggtcc
     1741 ctttgtaggc tttgccactt tttccgcgca agggagtcaa tacaagatcc tgttcggttg
     1801 ttgtcacctt atcccctcct tttctatctt ctgtaaccag ttatccctat tttacttgtt
     1861 ttaaaggact tagtcaatca tcttctttaa cttgtacggt aagtaaagaa gatttaataa
     1921 tcccatcgcc acaatcaaca caagagcatt ttgccaagaa cggcagagca caagattgac
     1981 gataagcatc aaaccactta attgcctcaa caaagaaagt agattccttt gcttatgctg
     2041 tggtttagtc gggtaaagcc cactcatata atggtaatca taatgatgat aaagtgataa
     2101 taactgaaaa agacttagat aatgaaagac caaggccaag cctactgcta aataagggtt
     2161 ggaaataaag gcaagtgaca agcaactaag caacaacaga cgtaaccata accctagata
     2221 atcagagctg cgtaaaaatg ctcttaaata taggtttgtc caaacctttt tactatctgc
     2281 cttgataagc ttaagtatag gattcaagta aggcctttcc ttaaccttgg ttgagattcc
     2341 tttaacattt gtaaacaaag cataaaactt taaaatggcc tgctggcgat ctgcctcaaa
     2401 agcaatcgct ttttcccaat caagcccctt ggagctcaaa aagcttgcca ccttacgctt
     2461 taacagtaag cgcttagcca gcaccaaaac accaagcaat agcacaaagg caagcaagga
     2521 aacaccaagc ctttgaaaca aaggaaataa aggtaacagc aagaccgttt gaaggctaga
     2581 ccaaagaata aaggacaagc gctctgctga cctgatatgg gcaataacct ctgcctcctt
     2641 ggtcagcaaa aaatgctgat cagccttttc aagataggta gcaactgacc ccagattaag
     2701 caaaaacaag acagcaatca acaaacctag ctgaatcggt agaggattag caggaaaatg
     2761 cttgagtagt tgactgtact gaaaaagaat aaagcccaaa agaaacagca agacaagaac
     2821 aaaatgatca ttaaagacat aaggcagata cttggtatgc ttgtgctgaa actcctgacg
     2881 acgcttacga aataatgcct tcatagctta cccctctttt gtcagcgcta ggtaaatgtc
     2941 attaagacta gctgaagcat ctccaaagac tgcctgcaaa tccgccagag tcccttgtgc
     3001 acgcacctgt ccctgatgca atatcacaaa acggtcacac attttttctg ccgaatccag
     3061 cacatgggta ctcattagaa ttgacttgcc ctttgccttt tcaacctcta aagccttaat
     3121 caaatcagca attgctaagg ggtcaagccc caaaaagggc tcatcaagaa taaaaagact
     3181 agggtcaatg acaaaagcgc aaataatcat aaccttttgc ttcattccct tagaaaaatg
     3241 caccggaaac caatccagct tatccgtcaa acgaaacagc tctaagaagg gctcagctcg
     3301 cttatgtgcc agctccacat caatatcata ggccatagct accgtattga tatgctctgc
     3361 taaggtcagc tcctcataca ggcttggtgt ttctgggata aagccaattt tcttgcgata
     3421 atcagcttca tgctccgcca aggttaagcc atcaatggaa atccttccct tatatggctt
     3481 taaaaaccca ataatttcat taatcgttgt tgacttacca gcaccattta gaccaataag
     3541 ccctactagc tctccatttc cgacagaaaa gctaatatcc ttcaaaactg gaatattaag
     3601 gtagcctcca gtgacattct caatgtttaa catatcattt ctttctaata tctaatctat
     3661 tgtagctttg catactagct tccctagatg acaggttatt agcctagaca gataggactt
     3721 actaggcaat gctttgtcat catcagccta tccagcgctt tgaagcactg ataagaccaa
     3781 ttagcttgac cctacttaag aaagctgggg cagctaatac taagggtaca cttatattag
     3841 ctattataac aaatttctgc acagagcgtt aactgttttg atcaatgctc ccatcagcta
     3901 aaaacgctga gtgaatctga agtctatttt aagatcatca agaaaaaggc ctagctataa
     3961 aaacagaggc tatattagct tgatctatca gtcctaacca tctatcacat catattcgaa
     4021 tgacctggtg atcctaaata gcagctcatc taaggcgtca tctaaaaaat catgataata
     4081 ttatcttatt gtattgaatt tttaataata taatgttatc gttaacatgt aaataagtgt
     4141 tgcgtcttta atgacaaagg aggtatgtta tgaatttgtc acgcttttta acatttggtt
     4201 tggtatcact ttcagcactt tcaatttcag gcctagtcca aacagaggct aaggctaacg
     4261 aatggcagac tatctttgaa aagccacagg aggtggttat cacagatggc tggcaaacta
     4321 tctctgaaaa gcctcaggaa gtaagcacgg ctaacgaatg gcaggtcagc tctgaagaag
     4381 ctcaagagtc tgttcctgat aaattctcac aaaacgaaga ccctagccta tgggctgttc
     4441 ctgataaatt ctcacaaaac gaggacccta gcctatgggc cgttcctgat aaattctcac
     4501 aaaacgagga ccctagccta tgggccgttc ctgataaatt ctcacaaaat gaggacccta
     4561 gcctatgggc tgttcctgat aaattctcgc aaaacgagga ccctagcctg tagtaaagcc
     4621 atccgcactc gattgaagat aaggcctatg ttgctgacgc ttcaatcttt ttttgttcta
     4681 aaagctttct cagccttaac tgtcaagaag ttccagcacc tcatactctc tgaaactctt
     4741 gtccttacaa atattgtgcc atgtcactac cgtacgatag tgcgcaaatg cacacctttg
     4801 acggacctag cttgcagcaa gtagcaggct tagttatgtg cttaaccata attgcttagt
     4861 ccattatcat gattcaaaag gctttgctag tcatgtggtc gataaccatt agcaccagct
     4921 ataaacaatt gcaatataga ccagtacatg ctaagataac tatagtatga gatagctatg
     4981 gtcactgagc aactactgat ttcttattct aaaattattc aactactgat ttgagccatt
     5041 gctacgcaga cgaaaggatt atcacatgga aaattgtatc ttttgcagca ttattagcgg
     5101 tgagattccc tcctccaagg tttatgagga tgagcaggta ctcgcttttt tggatatttc
     5161 gcaaacaaca gcgggtcata ccctcttgat tcctaaaaag catgtccgaa atatcctagc
     5221 aatggacgcc gagacagcta gccagacctt tgaacgatta cctaaaatcg ctcgcgccat
     5281 tcaaaaagca acaggtgcta ctgcaatgaa cattattaat aataatgaag agctagctgg
     5341 tcagactgtt tttcacgcgc atgtgcacct cgttcctcgc tacagccaag aagacgggat
     5401 cgctattcag tatacaacac atgagcctga cttcccagcc ctagcagcct tggcacaaca
     5461 aattagtcag gagattagcc aatgactcta aaaacaatga ccacaattgg tctcacatcc
     5521 gttttagcct accaagtgta tcgtaaacgt catcaaatca aagaaactct agtagccatg
     5581 caaacctcta agaaggctat ccaggccgat gttgatagga ttaaggcaaa tctcgccatc
     5641 attcaaaagg aggctcgaac gcttcaagca gcaggaacag aattagccta caaatggcag
     5701 gcctttaacc aagaagctca ggcccatctg actgaaatcc aacaacgtat gagcaagtac
     5761 cagcaggaaa ccccataagc ctaagcagac taccaagcct caaggtgaca aaaaagggct
     5821 ctatcgtttc tgtagtggac aagtccgcta tagggattat gggctctttt tgtatgtaca
     5881 aaaaagacga agaaatcact cacaggatca agccttgatg agatttcttc gtttttttgg
     5941 ctgtacccta aggcgctgct ggcgtaccag tggttgcacc acttgattgc tgctctgctg
     6001 gtgagtctgc ttgagggcta ggagtcacat tagctgctcc tgactcttgt gtaccagctg
     6061 ttgtgtcctg atagctgctg ctagaggacg tctctgagga ataggttgag tactgggtag
     6121 atgagtctgt ataggccggt aggctacctg aattgtaata atagctgcta tcctgagtag
     6181 actgagtttt taacgagcca taaaggtttt cgtaaactgt ggcagtcgtt tttagctgac
     6241 taagcttttc aaggcctaat tcagcacgaa tgcgattttg gatttctaaa agatgatctg
     6301 aggtcacaat ttgataggag ccgccatctg acaaggtcgc tccctcaccc tttagctgat
     6361 aggttttgat atttttaagg gcgtctgtat agcctaaaag attaggaatg gttcgtgatg
     6421 atatttcaat gttggtttgc atattaccac taacagctga caagatcttt cggtaggagc
     6481 tgatactgtt aagggcaaga atctttttca gcaccttttg aataacctcg cgctgacgct
     6541 tctgccgacc gtagtctccc tctggatcat catagcgcat tcgagcatag accaaggcct
     6601 gctctccatt tatcttgtga gttcctggtg caacggtagc ctgatactca ggctcattat
     6661 ctgcaataga gataggaaag tcaaattcat tggtaacagt aatgccacca acagcattaa
     6721 ccaaatcaat gagcccttgc atgttaatct gaacgtattt gtcaatcgtg atattcagca
     6781 agtcctgaac ggtcatgata gccatttggg caccaccagc tgcataagca gcattcagct
     6841 tagcttctgc tccattcatc tcattatcat ttggacctga caaagtgatg agaatgtctc
     6901 tttctaagct tgtcatggtt gtctttttgg tcttagggtt aatcgtaacc agaatcatag
     6961 aatcactatt tccttgccag gtagaggttc tgtgagacga tcctgtgtca actcccatca
     7021 atagaattga aaagggctct gtctgttgaa tggcatcact ttttttggag gacgttgcaa
     7081 aatccttaaa ggtctttgac aattctccag ttgaaaaggt ataggcattg gttaggtaaa
     7141 ctcccatagc ccccaaggtc aacagcacaa tagctgtcag cattaaaaag attttttttc
     7201 caattttcat ctattcacgt tccagatatt tacgcataag gtaaacatcc tgatagtctc
     7261 catttcttga tttgacgtcc tttcttttga cgccctctat tttaaagcca tatttctcat
     7321 aaatatgata ggcacaagta tttcgagcct gaacctccag ctccaaagca caaagctgct
     7381 ttgtttctct ggcccaatca agggtagtct ccatcaaaag ctgtcctagg ccatgattgc
     7441 ggtagggttt caagaccagc ataaagcaat cgccaacata gctagtctca cgatatgctt
     7501 tgccagctat atttagcaga ccagctaata tatctcccac ctttagcaaa aggcaaatat
     7561 ctgtcaaaga ctcctgacta gcctctagaa aacactcaag cacctctacg gtagcagcta
     7621 tgacgtcctc agtccctgtg ataaaatctg tctcatcagc agcttcttta attagagtga
     7681 tcaaagctga cgcatctgag gccttggcct cttcgattgt caccacctgc tcagacatgc
     7741 ttaagctcct caagaagtgc ctctgatcga tgaccatgtg ctagataatc aacctgccgg
     7801 cctgtttctg tttttgttat taaaatttca aggtagtcat gcagggttcc cttggctaaa
     7861 agctcgcccc actcaatcac agtaacccca ccaccaaaga taaaatcatc taaatcaata
     7921 gagtccggat catcaccaat ccgataaaca tctaaatgat acaagggtag tcttccctca
     7981 tattctcgag cgatagtata ggttgggctt ttaatcatct gatcaatccc caaaccctta
     8041 gcaaccccct tggtcagcgt tgttttacca gcacctaagt caccagtcaa gacaagcaca
     8101 tctcctgcct ttagctgtct accaatgcct tgcccgtaag cgattaattc attctcattt
     8161 ttgctataaa acataaggct attataacag aaaaaaaacg gtcttccaag cctaagccag
     8221 cctgtcagca aaatattcta ggctcgtcag tcctcatata atgtcgtcaa agctcaatca
     8281 gctttaacat ctcataaatc aaaagagcca gcagcaaatc acatggacct aacatcatgg
     8341 cattctgctg tgatagccag ggctgaatgc tctagaaatc aacccgcagc tctaaaacct
     8401 taagacttag cctaaatata ggactaggaa aaggtggcaa tgcctatgag cttagaaagt
     8461 ccatagtccc agtccaaacg gtaatccctg tctttattgt cccagcaaaa aagaggcacc
     8521 taagtacctc attagtcgtt tacaataacg ctaaaatgat aaaattcaaa acaaataaga
     8581 aggttgctcc ccaaagaatc gggtgaatct ccttggtttt gcccttcaca agcttcacca
     8641 agcaatagaa aataaaggag ccagccacac cgtatgaaat agagtagcaa agtgccataa
     8701 agaaagcagc aaagaaggac ggtagggcaa cgtcaaagtc gctccaatca acatcaagga
     8761 aggacgatac catcataacc ccgacaatga ttaaggctgg tgcagtcgca gcggctggaa
     8821 caattcccac gatcggcagc agtaaaacag ataagacaaa gcagacagca gttgatacag
     8881 ctgttagacc tgtacgtcct ccctctgcaa taccagcagc agactcaacg taggttgtgg
     8941 tatttgaggt gccaaataaa gctccgattg aagtaccaat agcgtcagca aagagcgcac
     9001 ggtccatttt tgagctaaag ccagagctgt tttccaaagc tctctcatcc tcctcagaga
     9061 aaatccctgt tcgacgacca gtcccaacaa aagttccaat cgtatcaaag gtatcagata
     9121 gactaaaggc aaagatcgtc attaaaacaa gcggcaagcg acttgaatca ctaaacagtg
     9181 acgccatgcc accaaaggca gccaagaatg ttgtccctaa ttcagcaaag gctgagctga
     9241 tgtgattgtc tgcaaaatta acagcagaaa gatcaaccac tccaatagga ataccggcta
     9301 aagttgtaac tgtaatacca attaggatgg ctccacgaac gttcttaagc acaagcactg
     9361 ctgttagcag cagaccaaaa actgctagca aaacactcgg atcggtgaag gttgaaatag
     9421 ctggaaccac accaccatta gcattaacag agaagacgcc attagcaaat gtttcagcag
     9481 ttgccttagc tggctcaaca ccatttacag taacaatctc agcagatgat agcgaaaagg
     9541 tgatcaggtt agcattttta aaacctagat aagcaacaaa gactccaata cctccgccaa
     9601 tagcatgctg caggcttact ggaatagcct tgataatgct cttgcgaagc tttgtgacag
     9661 tgataaagat attaaacaga ccacaaagaa agacaatagc caaggcctcc tgccaagaaa
     9721 atcctaagct aaaaacaaca gtgtaagtaa agaaagcatt aagtcccata ccaggagcca
     9781 atgcgtaagg cacattagca aacaaaccca tgatcaaggt agagatagca gctgcgatga
     9841 tggtcgctaa aaacaccgct tgcgacggca tacccgctgc actcaaaata cttgggttaa
     9901 caaataagat atatgacatc gcaaaaaaag tcgtcacacc agccatcagc tctgttgaaa
     9961 ccgtcgtgcc attttctttt aacttaaaaa acttttccat ttgaatggag tctccttatt
    10021 gataggcaaa atcaaaaaag cccttatctc atcagataag ctttttctct taaaaccaaa
    10081 tgattattat cgtttttacg aacgatatat tcatcgtaac attttatcgt tctattttca
    10141 atagcttttt tcgtttattt gccatgatcg ttcaaaattt aacagccttt ttttctatta
    10201 accgtccaag cagcaatttt ctcttccact gatcctaaaa tttgttataa tctagtgtat
    10261 gactaaaaaa ctaattgcta ttgatttaga cgggacttta ttgcatcacg acaataccat
    10321 ctctacctat actcaaaaaa ccattaaggc cgtccaagct aagggacatg aggtcatcat
    10381 ctcgacagga cgtccttatc gtatggctat tgactactac cttcagctag agctaaagac
    10441 acctatgatt agctttaatg gctctttgac ccacctacct gagcaaagat ggaaatacga
    10501 gcataatgtg actcttgata aggcatacct tctcaaactc ctagcagtgc aggaggactt
    10561 ccagatggac tttattgcta gtgagtaccg aaaagccttc tacattacca tgaataggcc
    10621 tgagagcatt gaccccaacc tttttggttt gaggccatca caccagatat ggctttacag
    10681 atcgacaaaa tcacgcagga tccaaatgct cttctcatgc aaacgcatca tgaggataag
    10741 tatgccctag ccaaggccat gcgcgccttc ttcaaggacg aaattgaggt ggactcttgg
    10801 ggtggtccct taaatatcct tgagatgtcc cccaaaaaca ttaataaggc ctatacctta
    10861 aaatacctgc ttagcattta caacaaggag cctaaggatt taatcgcctt tggtgatgag
    10921 cataacgaca cagaaatgct ggcctttgcc ggaaccggct atgccatgaa aaatgccagc
    10981 cctgtgctgc tgccctttgc cgaccagcag ctagcttact ctaacgaaga ggacggggtc
    11041 gccagaaaac tagaagagct tttcttgtga aagcaaacga aaccattgtt tttcagaaaa
    11101 cgatggtttt cttaatgccg tttccgtcaa ttgatgaaag aatttctaat attttcgtta
    11161 tttttcagca tattttcttt tttatgcggc ataaaaatcc ctttattatc aatattctac
    11221 ttattcggca gcgcattatg aaaatttttt catatttcgt aagatttttc cgaaagggct
    11281 tgatttttaa gtgaaaacgt tttaaaatag agacgttctt gaatttcgtt caagtgaaaa
    11341 agaattgcca aatgctattt ggaaggagat tattcttctt catttcaacg aaaaatattt
    11401 taataaggag gaagaacaag aatgggtatc ggtattatta ttgccagcca tggtaaattt
    11461 gctgaaggta ttcatcaatc tggttctatg atttttggtg aacaagagaa agttcaagtt
    11521 gtgactttca tgccaaatga aggaccagat gacttgtatg gacacttcaa caatgctatc
    11581 gcacaatttg atgctgatga tgaaatcctt gtactagctg acctttggag tggttctcca
    11641 tttaatcagg ctagtcgtgt ggcaggagaa aatcctgatc gcaaaatggc tatcatcact
    11701 ggtctaaatt tgccaatgct tattcaagcc tatactgagc gtttgatgga cgccaatgca
    11761 ggtgttgaac aagtagccgc aaacatcatt aaagaatcta aggacggtat taaagccctt
    11821 cctgaagagc tcaatccagt tgaggaggct tctacagcta atggtggtgg tcaagcgctt
    11881 caaggagcta ttcctaaggg aactgtcatt ggagatggta agctaaaaat caaccttgct
    11941 cgtattgaca ctcgtcttct tcatggtcag gtagcaactg catggacacc agcttctaag
    12001 gctgatcgta ttattgtagc gtcagattct gtggctaagg acgagcttcg taagcaattg
    12061 atcaagcagg cggctcctgg tggggttaag gctaatgttg ttccgatcaa taaattgatt
    12121 gaggcttcta aggacccacg ctttggcaac actcacgctc ttatcctgtt tgaaactgtt
    12181 caggacgccc ttcgtgcgat tgaaggcggc gttgagatca aagagctgaa cgttggatca
    12241 atagcgcatt caacaggtaa aacaatggtt aacaacgtat tgtctatgga caaggatgac
    12301 gttgctgcct ttgaaaaatt acgtgatcta ggtgtttcat ttgacgttcg taaggtgcca
    12361 aatgattcta agaaaaacct atttgagctt atccaaaaag caaatgtgca ataagcaatt
    12421 tagaaataag aggtaggctt gtttaacgca acaagctgtc tgcctcatct acaatgctgc
    12481 gatgatatga taagcctgat gattgcttct agacaaatca tcatcactta ataacgcttt
    12541 atattgtcca ttgacaattg actcatatac gaaaggataa caaaatgtca gatatttcat
    12601 taatttctgc aatcttggtc gttatcgttg ccttctttgc cggtcttgaa ggtatcttgg
    12661 accaatttca aatgcaccaa ccacttgttg cgtgtacctt aatcggactt gtgactggtc
    12721 accttgaagc aggtgttatg cttggtggta ctcttcaaat gcttgcactt ggttgggcaa
    12781 acattggtgc tgctgtagct cctgacgctg ctcttgcatc tgttgcagcg gctattatca
    12841 tggttaaggg tggcgacttt actcaaaaag ggattacctt tgcatactca acagctattc
    12901 ctcttgcggt tgcaggtctt ttccttacta tgattgttcg taccatttca actgtacttg
    12961 ttcacgctgg ggacaaggct gctttagagg gtaacttctc tgctatcgag cgcttccact
    13021 ttgctgcact tcttcttcaa ggcttgcgta ttgctgtacc agctgcactt cttgttgctg
    13081 tgccaactga ggccgttcaa agtgtcttga aggctatgcc agcttggttg aatgaaggta
    13141 tgcaaatcgg tggtgctatg gttgttgccg taggttacgc tcttgttatc aacatgatgg
    13201 ctacacgtga ggtatggcca ttcttcgcac ttggttttgc ccttgcagct gtgacccaat
    13261 taacacttat cgctatgggt gttatcggtg tggctattgc ctttatctac cttaaccttt
    13321 caaaacaagg tggtaacggt ggaggtcgag caggctctgc tgacccaatc ggcgatatcc
    13381 tagaagacta ctagaaaggg gtaagattaa tgactgaaca aattaaatta acaaaagctg
    13441 accgtaaacg tgtttggtgg cgttcacaat tccttcaagg gtcttggaac tatgagcgta
    13501 tgcaaaacat gggttgggct tatgcactta tcccagcact taaaaagctt tacacaacta
    13561 aagaagatcg tgctgctgca cttgagcgtc atatggaatt ctttaacact cacccatatg
    13621 tggctgctcc tatcatcggg gtaacgcttg cccttgaaga agaacgtgcc aacggtactg
    13681 ctattgacaa cgctgctatc caaggggtta agatcggtat gatgggacct cttgcaggta
    13741 tcggtgatcc tgtcttctgg tttacagtgc gtcctatcct tggtgctctt ggtgcttctc
    13801 ttgcacaaac tggtaacctt gtcggtccac tccttttctt ctttggctgg aacattatcc
    13861 gtatggcctt cttgtggtac actcaagaat ttggctacaa ggctggatct gaaatcacca
    13921 aagacatgtc aggtggtatc ctacaagaca tcactaaggg agcttctatc cttggtatgt
    13981 ttatccttgc tgtccttgta caacgctggg tatctatcaa ctttaccatc aaccttccag
    14041 gcaagcagct ttctgaaggt gcctatgttg tcttccctga gggagccgtt aaaggtgctg
    14101 agctaaaaag tattcttgga caagctatgg gtggcatgag ccttgataaa gttcaatcac
    14161 aaacccttca agggcaatta gactcattga tcccaggact tgctggatta ctacttacct
    14221 tcctttgcat gtggttattg aagaaaaaag tatcaccaat cgcaatcatc attgccttgt
    14281 ttgcatttgg tatcatcgca caccttcttc acatcatgta ataaaaatta aggaattggg
    14341 ggcttcccag ttccttaatt tttggctgtc tagagcctta gcaaaggcca gtattcagcc
    14401 tgctacaagc tatattttta tgttataata gacaaaaaca ctaaaggact tattatggca
    14461 caatctttaa atcaaagggt gatccttcag acaacagccg tctcctatct tggaatcgga
    14521 ggaaaggttg ggaaaatctt acttggagat aaggctttgg aattttacaa tgataaaaac
    14581 gttgaggact tcattcaaat tccctggacg gccattaacc aaatcggtgc caatgtttct
    14641 ggcaaaaagg tcagtcgtca ctttgaaatc tttaccgatc aaggcaaatt tctctttgct
    14701 tcaaaggatt caggaaaaat cttgaaggtt gctagagaaa caattggcaa tgacaaggtc
    14761 atcaagctac caaccttggt ccagaccata atagcaaagc tatttcatca tcaaaaaaag
    14821 gataagaaat ctcattgatg ggcctgcctt aattcaatat tacggtcata gaccagcatg
    14881 ataatactct tagacatagc accatagcaa tatgtctaag agtttttttc gttgctaaca
    14941 aaaaagcttg aaaaacaagc ttacagaatg tagacaaacc ctatcagcga tagaaaaatt
    15001 gaaaatttag aaattgacta tcatataatg aaaactctgg aaaatgctga tattacagta
    15061 tttttcagaa ttcttttgtt tttttgatta aaagaaaaag cttgaaaaac aagcttaagt
    15121 gaatcctttc tacaatctaa atctaacctt attcctcatc aatctgcaaa ggggattttc
    15181 ttgtccaccc atttcaacaa attttgaaag cctagttttt taaaaagcat cagccttgcc
    15241 tgttcaacca gaaaggacaa aaaataaatc acaatgccga cgccaaatat cagtagtggg
    15301 tataaaagga taggagcatt gacaaagggc tctgcaaaat cgcgaataat aaatttgacc
    15361 agcaaggggt gtaagtgcac cagataaata cctagagtcg ttggagacac gatcacaata
    15421 aagcgtagca gcagtgtttc tgatgtcagc ttcagcttag caaaaagaat aaataaggca
    15481 atagctccca aggtcaggct aggtgataca taccagtacc aaatatttcc caccataaat
    15541 ttcatgatat aggtaactac caaagatccc atataaaccg caataagaag cttatgacta
    15601 aacctactta gctctatcct ccttagatag gctccgataa tgtagagaat aatcagccaa
    15661 gtcatttcaa agcccttgct taaggaaaat tcatcgacct gctggttcat cagagctggg
    15721 atcaacgaaa aaatagcaaa aaccagcagt accaatcggc ctagctgctt attggataag
    15781 gtattgaggc caccattgat cataggcata aaaatcagta acccaaagta ggcggtgata
    15841 taccaataat tgccactcac tatgggaaag agggcctgac gccaattctc taagctaact
    15901 ggaaagccaa atagagcaaa caaaagggtc atcagaaagc tataaaagaa gacttgtacc
    15961 caaatattaa cgattttgga atatttatag ggcgacttaa tgcccacata gccactaatc
    16021 aacgcatagc aattgaccgc cccataaaca agaacctgaa tcatccaggt aacaataaaa
    16081 taagaatctg cctcaccttc gacagttgac cgcaagccgc cctttcccaa aacatgtgtg
    16141 atcacaatca taaacatgga aatgattcgc aataaatcta aaccgtaatg gcggttctta
    16201 tctaatgtca ttacattttt acgcataata ttagtttacc acaattttta atatttaacg
    16261 atttgatttt gtctgacaac gagatttttt gtgcctctga cctaagctct acttgtcatc
    16321 agccttttgt attactgacg ctccgtgaca gacacatgaa aaagttttag caagaaaaga
    16381 aagctttctg tatttcaagg atatgtcttg ttttttatag actttactat aggaaaaaca
    16441 ttgaaagtgt ctactctaat tccaaaataa ctagttcgcg cgtttgatgt agctgacact
    16501 catttgggag tttacttttt ctcctttttt gttataatag gtctagcgga taagtagtct
    16561 ggctctgtct ttcagagagt ctgtggttgc tgaaaacaga tagaggagtc atacgaaatt
    16621 ctaccgtcta ccaattaaat atgaattaag tgcacagatt gtgaagctgg atggaaccgc
    16681 gcttaggcgc tccagtgtat tcataggctg tgctttttta tctcgtcaga aataaaaaag
    16741 cgatcagcta gctttgctca tgctatttta taactgacta tcttatcacc agctcaaagg
    16801 agatttattt atgctagatc ttaagcgtat tcgtactgat tttgatactg ttgctgctaa
    16861 gctcaaaaca cgtggtgtgt cagaagctat cctaacctct ctaaaagcct tagatgaaca
    16921 gcggcgcacc ctgcttgttc aaacagaaga gctaaaagcc cagcgtaata tcgcctctgc
    16981 tgctatcgct caagccaaac gccaaaagga agacgccagc caacagattg ctgacatgca
    17041 gcagctagct gctaacatca aggcaattga tgctaagcta gctgacattg accaagaaat
    17101 taccggtatc atcactgttt tgccaaatac tccccatgat tcagttccta ttggagctga
    17161 tgaagaggac aatgtagaga ttcatcgctg gggaaagcca cgtcagtttg attttgacat
    17221 caaggcgcat tgggatcttg gagaagcctt agatatcctt gattgggagc gtggcgcaaa
    17281 ggttaccggt gctcgcttct tattctataa aaatcttggt gcaaggctgg agcgtgccct
    17341 ttataacttc atgcttgatg agcacctaaa agagggctat caagaaatca ttcctcctta
    17401 tatggttaat catgactcta tgtttggcac tggtcaatat ccaaaattca aggaggatac
    17461 ctttgagcta gatgggacaa actttgttct tatcccaact gctgaagtcc cattaaccaa
    17521 ttactatcgt ggtgacatca tagatggtaa ggagctgcca atctacttta ctgcaatgag
    17581 cccatcattt cgctctgagg ctggctctgc tggccgcgac actcgtggct tgattcgctt
    17641 acaccaattc cataaggtcg aaatggttaa gtttgctaag cccgaaacat cttatgaaga
    17701 gctggaaaaa atgaccgcca atgccgagca tattctccaa aagctaaagc tcccttatcg
    17761 tgtcttggct ctttgtactg gggatatggg cttttcggcc gctaaaacct atgatttaga
    17821 ggtttggatc cctgctcaaa acacctatcg cgaaatctca agctgctcaa ataccgaaga
    17881 tttccaagca cgccgcgcac aaattcgcta ccgcgatgag gcagatggca aggttaagct
    17941 actgcacacc ctaaatggct ctgggcttgc tgtcggacgt accgtagctg ctatcctaga
    18001 aaattaccaa aatgaggacg gctcagtgac gattccagaa gtgcttcgtc cttatatggg
    18061 tggactagag gtgatcaagc cacgttaaag ccaaagactg gccggataag gtgccaacaa
    18121 gacgattaat gggctctatc atttctgtag tagataagga cacagtagaa atgatagggc
    18181 ttttttctat gtacaaaaaa ggctctttat caattgtagg gggacaaaga gccgattaat
    18241 gagattgatc ctaacaataa agaagacctc tgtaactcct agctaactgc tagccttaca
    18301 gaggtctttt ttgatgtcct taatattttc taaagcgctg gtagcgctga tccaataatt
    18361 cctctaaggg cttggcctgt agctgagtga tttcgtcaat taagtgtgat tttatcatct
    18421 caacaatctc actcgaaaaa taaccccgct ccggaataat ccgatcaatg acgcccattt
    18481 gatacagctc agctgcggta attttcatga gctcagcagc ttcagtagcc ctagagccat
    18541 ccttccagag aatagaggca aagccttctg ggctaagaac agcgtacatg gtgttttcca
    18601 gcatccaaac ctgatcagca acagctaaag ctaaagcacc gcctgagccg ccttcgccaa
    18661 taataatagc aatgatagga accttgaggt cactcatttc catcaagttt ctagcaatag
    18721 cttcaccttg accgcgctcc tcagcaccta cgcccggata agctcctgct gtattgataa
    18781 aggtaatcac tggacgacca aatttttcag cctgcttcat taagcgtaag gccttacgat
    18841 agccctcagg gtgcggctgc ccaaaatttc tagccagatt atcttgaaga ttttttcctt
    18901 tttgaatacc aatcactgtg accggttgat cagccaaata ggcaatccca ccaacaatag
    18961 agccatcatc agcaaactga cgatccccat gcaactccat aaactcatca aaaatcaggc
    19021 tggcataatc tagagctgtc attcgaccct ggtcacgcgc ttcctttaat attcttgcga
    19081 cgtctgtcat gatacacctc catgaaatgc caccaaatga gcaatccgat cacgcaggtc
    19141 agtccgcttc acaatagcgt caacaaagcc atgctctttt aagaactctg ccttttgaaa
    19201 atcatctggt aaattttctc taactgtcgt ctcaatgacg cgtcgaccag caaaaccaac
    19261 caaggactgg ggctctgcaa taatcatatc accctccatt gcaaagctcg ctgtcacacc
    19321 acctgtggtc ggatcagtta ggatagtcag gtaaaaaagc ccagcatttg aatgtttctt
    19381 tatagctgca gaaaccttag ccatctgcat cagactcata atgccctctt gcatacgggc
    19441 tccaccagac gctgtaaaaa taacaactgg gagccgctca ctaatagcca gctcaaataa
    19501 gcgagtgatt ttctcaccaa caacggtccc catgcttgcc atgataaaat gcgaatccat
    19561 gatggctaga gcaagccttt gtcccttgac cagagctgtt ccagtcagga cagcctcatg
    19621 caagccagta gcctgcctgg ccttttgcag cttggcttgg tagtctggaa atcttaatgg
    19681 atccttggtt tcaatatctg taaacaattc ctgaaaagag ccttcatcaa cggttaaagt
    19741 caagcgctcc tgagcagaaa tcctaaaatt ataggagcag gtcggacaaa tctttgccgg
    19801 ccccagatcc ttttgataaa tcatgtgctt acaggcagga cacttggcaa ataattcgtc
    19861 tggcacctct ggaacattac gactgacaga gcttttgaga gaattattgg gagtaatacg
    19921 gatatatttg tcttttttac taaataaggc catatctact cctaatcttt attgtagctg
    19981 ggtaaaaagg tttccatcaa aaacgacgta tcgtaatcac ccgcaatcac ttgcttgtct
    20041 gaaatcaagt ccatctgaaa atcaatattg gtcataatac cttcaatctc taactcaaac
    20101 agagcccttt gcatcttcat caaagcatca aatcggttat ctccatgaac gataatctta
    20161 gcaatcatac tatcataata aggcggtatc gtataaccac tgtaaacagc agaatcaatc
    20221 ctaagcccaa cacctccgct tggtaggtaa agatctgtaa tcttaccagg gcttggtgca
    20281 aaattaaagc ttggattttc tgcgttaata cgacactcaa tagcatggcc agtaatcaca
    20341 atatcctctt gacgaactga taaaggaaga cctgctgcga tccgcaattg ctccttgaca
    20401 atgtcaacgc ctgtaacaaa ctctgttacg gggtgctcta cctgaacacg cgtattcatc
    20461 tccataaagt aaaaatcacc gctggcttca tctaataaga actcaattgt gccagcattc
    20521 tcataggaca ccgccttggc agcacgaaca gcagcttcac ccatcctttg acgcagtgtt
    20581 gtgccaatcg caatcgaagg gctttcctcc agtacctttt gattgttacg ctgtaaggag
    20641 caatctctct ctccaaggtg tatcacatgc ccctgtgaat cacctaaaat ttgcacctca
    20701 atatgccttg ccggataaat aaccttctcc aaatacatgg caccattacc aaaggctcct
    20761 aaagcttctt gactagcagc gttaaaagca gcctctaaat cagcctcgga ttcaaccttt
    20821 cggattccct tgccgccacc gcctgcagca gcctttagca ttactggata gccaatctgc
    20881 cttgcaatct caagagcctc ttgggcattg taaacctcgc cgtctgagcc tggaataaca
    20941 ggaacacctg ccttaatcat ctcagcgcgg gcgttgattt tgtcgcccat tttatccatg
    21001 acagctcctg aggggccaat aaacttgatg ttcatttcct cgcacatggt cacaaatttt
    21061 gaattttcac ttaaaaaacc aaaccctggg tggatagcct gcgcccctgt caccacagct
    21121 gctgataaga cagaattcat attgagatag gattcctttg atcttgacgg tccaatacag
    21181 atggcttggt ctgccaagat cgtatgtaaa gcctctctat cagcctcaga ataaacagca
    21241 actgtggaaa tgcctaattc tcgtgctgca cgaataatcc gcactgctat ttcaccacga
    21301 ttggcaatta agattttgtt aaacataggt tcttttttcc tccacagacg attagtcttt
    21361 tactgcccaa aagcaaaggt caaggtccca ctagctgcta atttgccatc aacctctgcc
    21421 ttggcctcaa caactgctat tgtcccacga cgcttaataa acctagctgt catgactagc
    21481 tggtctcccg gaaccacctg ctttttaaat tttaccttgt ccataccagc gtaaaaaaca
    21541 agcttgcctt tattttcctc ttttgatagc tccaagacgc cagcagtttg tgccaaggcc
    21601 tccatgatca aaacacctgg catgactgga tactgaggaa aatgaccgtt aaagaagggc
    21661 tcattgatag tgacattttt gatggcaaca atttcatcgt ctgaagcctc taaaattcta
    21721 tcaacaagca gcattgggta gcgatgtggc aatgcctctt gaatctgttt tatatccatc
    21781 atttaatgcg taccaatcct tgtccaaact caaccacgtc ctcattggcc actaaaatct
    21841 ctgtcacgat accgtcgcaa ggagcaggaa tctcgttcat gaccttcatc gcctcaacaa
    21901 ttaacaatgt ctgtcccttt ttaacgctat caccaacagt aacaaatgga ggcttgtcag
    21961 gaccggcagc aagataggcc acaccaacaa gaggactgtc aactacttct ccttctggct
    22021 cttgcagacc tgaagaagca gggattgatt cctgtttaga gacaatctcc tgcgtcaggc
    22081 taataggggc tacctcctgg tgcaaagtaa caggctcagg agctggagct gccatcggac
    22141 ggtgctcatt tttactaaat aacagctccc catcacttga tttgaatgaa aattcgcgta
    22201 ggcttgacgc atcaaactgt gccatcaaat cctttatctc ttgaatattc attttaatcc
    22261 tcccaacgct taaaggctaa tacagcgtta tgacctccaa agccaaaggt atttgacatg
    22321 gcataacgaa tatcggcttc ttttccttgg ccaaaaataa catttgcttc aatatcatct
    22381 gacagctcct ttgtcccagc tgtcattgga acataattgt gacgtattgc ttctatggtt
    22441 gcaatagctt ccacagcacc agctgcccct agtaggtggc ctgtaaagga cttggttgat
    22501 gagacaggaa cctctttacc aagcactgca acaatagcct gactttctcc tttttcatta
    22561 gcaggagttg aggtgccatg agcattcacg tagtcaatag ctgctgcatc aataccggcc
    22621 tcctgcaatg ctagattaat ggccttacga gcaccaagtc cttctgggtg tggtgaggtc
    22681 atgtggtaag cgtcacaggt attgccgtag ccaacaatct cagctaaaat agtcgcaccg
    22741 cgcttttgag catgctctaa gctttccaaa acaagcatac ctgatccttc acccatgata
    22801 aaaccgtttc gatccttatc aaatggaata gagctgcggc ttgggtcctc agttgttgac
    22861 aaggcagtca agctctggaa gcccgcaatg gcaaattttg taatggctgc ctctgatcct
    22921 ccaaccatca tcacgtcttg aagaccaaac ttaattgtac gaaaggcatc gccaatagca
    22981 tcgtttgaag aggcacaggc tgtattgatt gacttacata cgccttgggc attcagcttc
    23041 atggcaacat taccagccgc catatttggc aaggcctttg gtagagtcat cggcttaacg
    23101 cgctttggtc ctttttcatg taaccgaatc acctgctctt caatctcttg aatgcctcca
    23161 ataccagacg ctacaataac accaaagcgg tcagaatcaa tcgcttcaat atctaggcca
    23221 gcatgttcaa tcgcctctgt cgcagcatat aaggcataca aggaatacat gtcaaagcga
    23281 tttagatcct ttttgacaaa atacttatca aatggaaaat cctgaatctc tgctgcattc
    23341 ttaacagcga agtcactcgt atcaaatttt gtgataggct taataccaat atgacctgcc
    23401 tttaagcttg accaaaactc ctctggagta tgcccaattg gggaagtcac gccataacct
    23461 gttacaacta ctctgtttaa tgtcatttta atacctctat tttattgcat tgtcatgccg
    23521 ccgtcaatgg caagcacctg accagtaata taatcctgac tagctaggaa gcttgctgcc
    23581 tgagcaacct cttgcccctt gccaatacgc ttcattggga tttgatttaa gatttgctct
    23641 tgcatctttt cagaaaggac acctgtcata tcagattcga tgaagcccgg tgcaatcgca
    23701 tttacccgaa tgccacgcgc cgcaacctca cgagcaactg acttggtaaa gccaatcaag
    23761 cctgccttgg acgctgcata atttgcttga ccgatatttc ctgttaggcc gacaacacta
    23821 gacacattga tgatagcacc ctgacgagcc tttgtcatcg gctttaagac cgattgtgtc
    23881 atgttaaatg ctcctgtcag attgattttg agaacacgct caaagtcctc ctctgacatc
    23941 ttaagcatta atttatcatt agtgatgcca gcattgttaa tcaaaatgtc cacagagcca
    24001 agctgctcaa tagcctcatc aaccattcgc ttagcatcag ccccctctga aacatctcct
    24061 gagatcggca caaccttcac accgtaatcc ttaaaggtct ccaccagctc atcagaaatc
    24121 gctgagcgac cattgagaac gatgttggcg cctagtcctg caaattgatg agccattgct
    24181 agtccaatgc ctcttgttga ccctgtgata aaaacgtttt ttcctttaat ttccatagct
    24241 tagcattccc tcctattttc ccaaatacaa ttgtaggctt ggcatatctt caacactgct
    24301 gcatagcagc tttttgtcga tttttttaat aaagcctgtt aaaaccctgc cagggccaat
    24361 ctcaacaaac tgggtgatac cgttagcctt cataacctcg atactatcat aaaaacgaac
    24421 aggctccatg acctgacgcg ccaataattc tgcaatccga tccttttcca tgaccttagc
    24481 ctctgtattt ccaaccagtg gcagatcaaa gtcctgaaat tgaatcttgc tgagctcctc
    24541 tgccaacctt tgactagcag gcgctaaaag tgctgtatgg aaaggtcctg agacattcag
    24601 cggaattaaa cgcttcactc cctttgcttt taagatttca agtgccgcat tgacagcctc
    24661 agctgtccca ccaataacaa tctgtcctgg cgtattatag ttagcaggtg acacaacacc
    24721 aaccgaagaa gcctcttgac aagcctcctc aataagccta gcctctgtat tcatcacagc
    24781 taccatctta ccagagccag caggcgctgc ctcctccata aagcgtcccc tttttgcaac
    24841 tagctctagg gcagtctcaa aactcagaac acctgccgca actagagcag aatattctcc
    24901 aagagaaagc cccgccacca tatcaggatg aaccccataa gaggttaaga tacgataaat
    24961 ggagactgaa gcggttaaga ttgctggctg cgtgtaggct gtctggttca accgatcctg
    25021 gtcggtatca atgagcttgc gtaaatcata gcctaaaagc tgactagcct gatcaaaggt
    25081 gtcacgagca atggcatatt ggtcatacaa atctcttgtc atgcctagtg tctgagcacc
    25141 ctgaccagca aataaaaagg ctgtttttgt catacttctc cttatttata tcgtttcgtt
    25201 tttgtcatca gctgcaagag cttgccagcg cttagcttct tgactaatca ctgctgctgc
    25261 accatagtag atatccttta ggatggcttc acagctttct tctgctctaa ttaagcctgc
    25321 aatctgccct gccatgacag agccattgat cacatcacca tcaatcacag cgttgcgcag
    25381 agctcctgct cccatttctt cgatgtcact agcagcctta cgatctgcta aaaattcttt
    25441 ttcagcctta gcataagctg atgttagctt atttttgata gagcgtaccg gatgaccaac
    25501 aacttgagct gaaatgacag tatcaatgtc cttagccttc aaaattttat ccttaaagct
    25561 ttggtgagca ttagattcct ttgccacaac aaatcgagtt ccaacctgaa cagcctcagc
    25621 acccagcata aaggctgctg ctgcacctcg accatctgca atcccacctg ctgcaataac
    25681 tggaatagaa acagcatcta ccacctgcct aaccaaggtc atcgttgtca atttaccgat
    25741 atggccacca gcctccattc cttcagcaat aacagcatca acgcctaatt tttccatgcg
    25801 cttagccagg gcaacgctag gaacaactgg aatcacgata atacctgcct catgaaggcg
    25861 ctccatgtat ttccctggat ttccagcgcc agtggtcacc accttgacac cttcttcgat
    25921 caccaaatcg acaatgtcat ctgcaaaggg agatagcagc atgatattaa ccccaaaggg
    25981 cttatctgtg atcgctttga cacgatcaat atttgccttg accacctctt taggagcgtt
    26041 tcctccacca atgatcccaa gaccaccagc attggagaca gcacctgcta gatcaccatc
    26101 agccacccag gccatacctc cctgaaaaat gggataatca atattaagta attctgtaat
    26161 acgtgttttc ataataacct tctatgcaaa gaaatcagga gaataatttg ataatcaaac
    26221 tatcataata agaagaaaga gcgagttaga gcctgaaaga gggtctaatc tcaccctgat
    26281 ggttcgatta ttacatatca attgaccaac taaagcagtt cattaatcag caggctggtt
    26341 aatcagtatt ctcgcttgtt tgagctttat tttgtttttt cttcaacgta ggcaacaagg
    26401 tcaccaactg tgtttaagcc ttcttctgtt tcgatttgaa tgtcaaaggc atcttcaatt
    26461 tctgagatca cttggaaaac atcaagtgag tcagcatcta aatcatcaaa ggtagtttct
    26521 aaggttactt cctctgcgtc cttgccaagc tcctcaacga taatttcctg tactttttca
    26581 aatactgcca ttttatgtct ccttaatata aatatttatt ttataaatgt gctaggcaca
    26641 tgatataact agattttaac aattagactg ccccatgtca aacctccacc gaagcccgac
    26701 agtaaaatat gctggctgcc gtctaattta agctgtccat tttggactga ttcagatagc
    26761 aaaatcggta tactagctgc actggtattg ccatagtgca tcatattttc cagaaatttc
    26821 tctcttggca taccaatttt cttagccatc ttatctaaaa tacgccgatt ggcctgatgt
    26881 aaaagcagat agtctaactc ctccttggcc aagcctgatt gctcaataat tgctgtaatg
    26941 ctccttgaaa catctctaat cgcaaagtca aagatagcac gaccatccat ctgaagaaag
    27001 gagttgacct cctgtccttg agaaaatggt gagcgcagac tgctctgacc tgatgtcagg
    27061 ctttgacctt gcgcaccatc agtatgtaag gcctcagcta gaaaatgctg ctgctcgctg
    27121 gcctctaata aaaccccacc agcaccatct ccaaataaaa cagctgtgct tctatcctgc
    27181 caatcaataa tcttagacag ggtctctgct ccaataacca agcctctttg ataagcccct
    27241 gatgcaatca acttatccgc cattgctaag gcaaagacaa agccactgca ggccgctgtc
    27301 atatcaaaag caaatgcatt agtagcaccg atagcagcct gaacctttgc tgccgtcgat
    27361 ggcatgctag catctgggct aatcgtagca acgatgataa aatcaagtgc agtcgcatca
    27421 tatcctgacc ctgctaacaa ttgctctgct acccgaatgg ctaaatcact ggtcatctcc
    27481 acagtggaaa tgtgacgctt ctcaatccca gtccgtgacg aaatccattc gtggctggtg
    27541 tccatgattt gcgacagatc gtcattacta ataacctgct taggcgtata atgagctacc
    27601 tgactaattt ttgaaaagac cattaaacca aatcctccaa aaactgatgt aagttcccca
    27661 agccacgtaa cagggcttgc atttcgtcct cattcatatc agcgatcaca tgaccgacca
    27721 tatttttatg gaatcttgca tggagacgat ccagaagacg cccctttttg gtcagtgaca
    27781 ggtaaacaac ccgtctatcc acgcttgatc ttgttctttc aatatagccc tttagctcta
    27841 gcttgtttaa gctagtggta accgttccta aggtaaccat gagctctctt gcgatgtcac
    27901 ttggcgttac ctgctgatat tttccaataa tctcaattgt gtgcatctcc tttagagaaa
    27961 catcattaaa ttgacttgtt tttaagctca tttcctcaat aaccaaaatt ctgttgaaaa
    28021 tatcaactaa atattgatta atcttattat attccaagta aacacctccc tagctgtaaa
    28081 atactttgac tatcaaagta tatcagacat caaagtattt tgcaagcaca taagagctat
    28141 ttcccccgaa aatttggccg cctcctatct ccataagccc tgacgccctc tttaaagtcc
    28201 tccttaaagg ccaattcctc ttgaatagca agctcttttt gggcataatc ctcccaacct
    28261 gcaaaaaagc tttgccatac caaagatttc atgccggcgt aggaatttga agagccacgc
    28321 ctcaaacgct ttaacagctg actacaggtc ttatcaagct tatctgactc agcagctcga
    28381 tagacaaatc cgtactcaag ccctttttct gctgtgaccc cctcaccggt catcaccaga
    28441 tgagtcgctc tatttagacc aacggcacgt gttaacaaga aaagaccacc agcatctggc
    28501 gctaagccga cattaacaaa ggcctgaata aattttgtct gggtgctagc aatacaaaaa
    28561 tccaccgcta aggcaatatt aaaggccgca ccagccaccg caccatcagc acagaggata
    28621 accggctttg gcaattgctt gatagcaaag gaaatatcct gaaccagctc agcaatccta
    28681 actagagact gaacatcatc tctttcaaca gcattttgca tctcaaccaa gtcaccaccg
    28741 actgaaaaga ccttgccctt tgccttaatc actaaaaagc gcagagaggg gttatcctta
    28801 accaacctaa tagcctccag aatctcctga caggctggaa tgttaaagcc attagacacc
    28861 tctggacgat ttaaggttaa aatggccaga tcctcttcaa gctcaaaaat gatattttga
    28921 aacgtcatat cactcctctt ttctgacagc ttatttgatt accaaataat tttatgacca
    28981 aataatttga caatcaaatt aattactaga ctatagtaca ctagaatcag tcgttatgca
    29041 agaaaaagat tgtaaaaaat acattaaaat tgactgcgca atttaaagca tgcagcccta
    29101 aaaccaagct cagacctagc ctctatacct ctaataaaag agcctaagac aaaagtgtcc
    29161 tagactctga aactttggca tgtgctatgc tcaaccattc tatacaattg tgatcaatcg
    29221 ctcatagagt gtgtaaacaa gacccgctta aatatcctct agagcgtctt tgaccttgtc
    29281 aaagaaacct tttttctttg gagcaatcgg cttttcgcca ctagcctccg caaaagcctt
    29341 caaggcctcc ttttgagcct cattgagctt ggtaggcgtt acaatgttta cagttacatg
    29401 ctggtctcct tggcctccgc ctcgaagctt aggagccccc ttgcccttca agcgaaatac
    29461 cttaccagtt tgtgttccag cgggaataga catggcaaca tcaccatgga ccgttgggat
    29521 atctactgta tctcccaaag cagcctgaac aaatgaaata ttcaagctgt agtaaatagt
    29581 agagccattg cgctcaaact gtttacttgg aagcacgttt aaaataacga acaaatcacc
    29641 ataaggtcca ccattaaagc ctgcttcccc ctgaccctgt aggcggattt gttggccggt
    29701 ttcaacacct gctgggattt ttactgaaac cttatgaacc ttcttttcat gaccagttcc
    29761 atgacaggta tggcaaggct ctttgatttc ttgaccgctg ccatgacaga catcacaggt
    29821 cacctgacga cgcatcatgc caagtggggt ctgcgtatca acattgataa cccctgagcc
    29881 atgacattta cggcaggttg taggacttgt tccaggctta gctcctgagc ctgcacaggt
    29941 gctacaggtt gattcacgat gatagctgac ctctttttcg gtaccaaaaa cagcttcctc
    30001 aaaagaaagg tttaccctat attgaaggtc atcgccctga cgtggagcat tgggattacg
    30061 cataccacca ccgccaaaaa agcttgagaa aatatcctca aagccgccaa agccaccacc
    30121 atcgaagccg ccaaaaccgc ctgcgccacc accaaagcca ccgtttgctc cggctgcccc
    30181 gtattgatca taggctgcac gcttttgtga atcgcttagg gtttcatagg cttcctgtac
    30241 gtccttatat ttttgctcag ctcccggctc tttattgatg tctgggtggt atttcttaga
    30301 catcttacgg taagctcgtt taatatcatc ggccgaagcg tcctttgaga ccccaagacg
    30361 atcatagtat tccgtattat tcatttattc tttccttcat tgacaaaaac agacggagcg
    30421 aggcgccccg cctatttgat ttttatttat ttagccttgc tatgctattt tctagcaatt
    30481 aggggagggg actatcgcct cagtttctag ctttactgag cgaccttagc tcctcacagc
    30541 ttatttttca gtgaactcac catctacaac atcatcgcca ctgtttgttg agcctgtatc
    30601 tgctgcacct tctgcaccag cctgggcttg ttgtgctgcg gctgcttgct cgtacatttt
    30661 aacagcaagg gcttgtgctt tttcattaag cgcttcaagc ttagctttca tatcatcaag
    30721 gtcgcctgac tcttgagcct tcttaagctc atcaagagct gtttgagcag catcacgctc
    30781 tgtgtcaaag cctttgcctt cagtttcttt aatagtcttt tcagttgcaa agatagcctg
    30841 gtcaacttca tttttaaggt caacctcttc cttacgtttt gcatcggctt cagcattggc
    30901 ttcagcgtct ttcatcatgc gttcaatttc ttcttcagaa agaccatcgt tagatttgat
    30961 gacaatatgt tgttcttttt gagtacctag gtcttttgcc ttaacagaaa caataccgtt
    31021 tttgtcgatg tcaaaggtta cttcgatttg tgggatacca cgaggggctg caggaatgtc
    31081 tgtcaattgg aagcgtccaa gtgttttgtt atctgctgcc attgggcgtt caccctgaag
    31141 cacgtggata tcaacagctg gctggttgtc tgctgcagtt gagaagacct gtgatttaga
    31201 ggttggaatt gttgtgttgc ggtcaataag ctttgtaaag acgccaccca ttgtttcgat
    31261 accaagtgac aatggtgtca cgtcaagaag aacaacgtct ttaacatcac cagtgatcac
    31321 accaccttgg atagcagcac ccatcgctac aacttcatca gggttcactg atttgtttgg
    31381 ctctttgcca gtttcagcct taacagcttc aaccacagct gggatacgag ttgaaccacc
    31441 aacaaggata acctcatcga tttctgacaa gctcaagcct gcatcagaca gcgcttggcg
    31501 aacaggaacc ttcgtacgct ctactaaatc acgagtcagg tcatcaaatt ttgcacgaga
    31561 caggctcatc tctaagtgaa gcggaccagc agcgccagca gtgatgaatg gcaatgaaat
    31621 ttgagtttga gtgacacctg aaaggtcttt tttagctttt tcagcagcgt ccttcaagcg
    31681 ttgaagagcc attttatctt gtgataggtc aataccgttt tctttcttga attctgctac
    31741 taagaaatca atgatttttt ggtcaaagtc gtcaccaccg agcttgttgt caccagcagt
    31801 tgcaagcaca tcaaagacac catcacccaa ttcaaggata gacacgtcaa aggtaccacc
    31861 accaaggtca aagactaaga tcttttcttc tttatctgtc ttgtcaagac cgtaagcaag
    31921 agctgctgca gttggttcgt tgacgatacg ttctacctca agcccagcaa tcttacctgc
    31981 gtccttagta gcttgacgtt gtgcatcgtt gaagtaggca ggaactgtga taacagcctt
    32041 tgttaccttt tcaccaaggt agtcctctgc atagccttta aggtattgaa gaatcattgc
    32101 tgagatttct tgtggtgtgt attctttacc attagcagca accttttcag aggttcccat
    32161 ctttgatttg attgagataa cagtgtcagg gtttgtcact gcttgacgct tggcagcgtc
    32221 accgacaatg atttcaccgt ttttaaatga cactactgaa ggggttgtgc ggttgccttc
    32281 tgggttggca atgattttgc tttctgttcc ttcaagaact gctactgctg agtttgttgt
    32341 tcctaagtca ataccgataa ttttagacat aatatttttt cctcttttat atatttatga
    32401 tactcctctt atgtggcacg gacgctagca gcttcctatg gaatctcata gctgaaattt
    32461 gagcctaaag tctcaaattt tccgagtcat aaaacactag tgttttatga cttttgccac
    32521 ggcgaagagt atcggtaatg ctcacttcgt tcgcttttgc tagcgcaaaa agcagcaatc
    32581 ttatttctta ttttcatagt ttaccgtcat ttcggacatg attcatttta ttgattagct
    32641 atcatcacgg gataattgcg acgtgagata gcaaaatcga taccattttg ctatcgagct
    32701 agtaaggagt ctaggcaagc cgccacagcg gttgccgtct aatgacgagc catttcaatg
    32761 gccatcatta gtgactagtt gtacacaacc accatcgctg gtcttagtaa gcgctcatga
    32821 agcttatagc ctttttggaa aacctgagcg atactatctg ctgggtggtc atcatctgct
    32881 ggtagggttt ggactgccat gtgcagattg tggtcaaagg cttccacagg aacctcttca
    32941 ataccttctt ctttaagggc ttgaacaagg ctttcttgca ccatttctag gccttttttg
    33001 acatcatctg tcagaccctc aacagccaaa gcacgctcca agttatctaa gcttggaagg
    33061 atttttttag ctaaatcctg tgaacgatag cgctgcaagc tttggcgttc ttcattcgca
    33121 cgacgctgaa tattttgcat ttctgcgtga gctctgaggt atttattttc aaaatcttct
    33181 gctcgctgga gagccaactc tagctcagat ggttcctcgg ctgcttcatc agcaataagc
    33241 tcagctgatt gatcagcttc ttcaactggc tctactgctt cctcagcagc ctcatcaaga
    33301 atgtcctctt gatccttgag ctcttctttt ggttttttag acaaggtgtc tacccctttc
    33361 ttacattttc ttaaatcata ttaaggcctt agtgaacctc ataatggttg ctgtttaagt
    33421 aacggtaata atctcttagc ttcacagcca gtagctgacc aatcacatta atcaagctaa
    33481 cactacgacg ataatccata tcaactggcc caattaagct taagaggcca aatcctctgt
    33541 atggaattaa aaacttgtag gtcagcaagg tcacgtttgc tagggctggc tcactgctgt
    33601 cagcaacctg aaccgttgcc atctcttcct ctgatagact ctgtctgata gatagggcta
    33661 agcgctgctc ctcatcaaga aactgatagg tcgcaagacc agcatagtca agggcagcaa
    33721 ccttgccaga gacaaaaatc gtttctcgaa aaagcccgac aaagatataa tcaaacaaat
    33781 ccaaaacatt gtctgtcacc gtaaaatact tctgaacaat ctgagggatt tcggttcgca
    33841 gcttgtaatg aacagtcata acatctttgc caagtaagcg atcagcaaca atgcccttaa
    33901 gcaccagcaa atcacgattc ataaaattct taggaatggc aaactgtacg gtcaacggct
    33961 tggactcatc taagctcaaa actgccaagg catcatgact agatagctga acaatatcaa
    34021 agcctgtcag cctttgcctt gcaggctcaa catctaaaat cgccgccgta tagccggtcg
    34081 tatccgatag catctggctg gctcttagca aaacgtcctc cagcttaaag gcctcaaaat
    34141 caaaggcctt gaccagctga taaaggtcct gctcatcaat gctgccaaga ttaagagaat
    34201 gctctacaaa atatttaaag cctgccgcac ttggcatgcg cccacttgat gtgtgagcct
    34261 tctccagcaa tcctagtttt tcaagctttg ccatgtcatt tctaatagtg gcactactag
    34321 aagcaataag tgactgcaaa gccttagagc caactggttc atgggtctgt gtaaataaat
    34381 ctacaataag attcaaaata ttagattgtc tctctgtgat cacaaaccaa tcactccctt
    34441 tctgttagca ctctatacat cggactgcta atttataatt ctattatatc cttttaaact
    34501 agcatgtcaa gaaaaaaact caaaaaatta gcactctttt tttagagtgc taatttttat
    34561 aaaacattga cagtgttgcc tttgacatta tgcttgaaag aagtaataga gagccactta
    34621 ctacctctca gactggtatt ggcttctccc gactcgctag ctaaaaggag cgctaagctg
    34681 taagggggat tagcttaact gcctgaagcc ttaaggccta acaatcaagc ctttagtaga
    34741 gcaggataaa tcaggctgcg tgctcacagc tcctactctt aaggcttaca ccttcaagct
    34801 gatagaaagt tgcaatacct actaaagcaa atacctgagc ttaccggttg tttcggtgtc
    34861 tttttcatct cctcaatcat catagcttgt caaacctctt gcttcaatca gctgcacaag
    34921 cctttgggca tagcccttat catcagaata gcgataggtc tgcagacttt tagcaggttt
    34981 tttataccct ttttcggttg ctaggctttg gtaaagcttt ttctcctcgc ctgtgccttg
    35041 actaagccat gataagtaag ctctgataga gtcctctctg tcccgataga tagcataggc
    35101 tgtcttgtgc tttgaggctg cttgcttctt gaggctaatg gaagcctgcc ctggagctgg
    35161 ctgcagtgaa aaaaggttgt ggtatttggc cgccaacagg gttctgccat aattggtttc
    35221 taaaataatc tgaccaatca aaatagaagg acgaatgcca tagtttttgg ccaatggctt
    35281 gacctcctta gcaaccaact ggataaattg cctctctgta tagggaacag acatctcctg
    35341 actggccgat gtgcctttgg cattgaacag caagggacca atcaaagcca ccataatgaa
    35401 cactaaaaac actagaaaat aggaaaattt aagtcgtttt ctcatttttt ctccttcaat
    35461 cgtgttaggt attcttctag gctgaggcta tgagcggtaa tgtatagggc agaggcttta
    35521 ccaacatagc gataatgcca gtcctcatac tcaatccctg tgctagtctg cttccctttt
    35581 ggatagcgca aaataaaacc aaattgtgga gctatttttt gaatctcctg tgccacctta
    35641 ggatcactag cgtttaagtt atctactgtg ctcatatcaa tggctagacc agtctgatgt
    35701 tcactagtgc ctgctggctg ggcatatttc cgaaccaagg cttcagctgc ctcttgggtc
    35761 aggctaggat catttgccag ctcttgggca atataagact gataaagctc ttcttgctgg
    35821 acaaccgaac gataaccagc aatcaagtgc tcctgaggtt caatcgtctg cgccgctgct
    35881 agaaaatcag ccgtctcctg ctcaatgcgc ttatcaatag gaatcccatt aatctcaacc
    35941 aactcaggac tcatttcctc ttgagggtga tcgcgattga caaggaccag ctgccagtcc
    36001 gtagttgata cctttggcag atcagtagtc tttttagcct gcttagctgc ctttggggca
    36061 ggtactgttt gattagcctt ggggcctaca gcctgttttt caggcttgat aaagaggtaa
    36121 acccctgata aaaacaacag gacgaccaag gcctgtaaaa ggactcttat agtgttattc
    36181 ttcatctctt attgactcaa ttatctcacg accacgatag cggtagctca tatctccaat
    36241 cgttttgatg gtaaactgcc cattctcata ttccacaaca gtgacgcttc cattgtcaat
    36301 gtattgcttt tccctatctg ggtcaattag ccacataaag gttccaatgg tcatgccatg
    36361 actaaccacg atagcattgc cacctcctgc attttcaaca gcaagcgcga tagcctcaaa
    36421 gccctcatag atacgcttgc tcaatacctc ccagggctct gcccagttag cagtatcaac
    36481 ctcgacaata ctctctgcta attctgaata aggcacatca cgcagattgt cacgattttc
    36541 aaaggccttt gttctaggta aaacacctaa aaacagctcg gaatcataag ccccatctag
    36601 actaccaaag caccactcac gaatccgctt atctctagtg tagggtaaaa actcattttc
    36661 agactttcgt agaataatct ccattgtctg catggtacga cctgaatcac tcgaaaaagc
    36721 agccttgaat ggaataccag cagccttcaa accaagtccc aattcacgaa tcccttcttc
    36781 tcctgccttt gtcaaggggg tatcactcca accctgtgca cgaccaatgg tgttgaacat
    36841 cgtcttgcca tgtctgacaa tgtataatct tgtttttgtc ataatgaacc tccaaagtct
    36901 ctctgctatt atagcattaa aagaaaacac ttgcaaaacc atgcaagtgc tagccgttaa
    36961 ttcttaaagc tatggatagg agctggtatc tgcccaccac gagcaataaa gtcagccgat
    37021 gaatgcggat taacagccat aaccggagct gtccctaaaa gaccaccaaa agcaatcata
    37081 tcaccctcct taccctttgg aataatacga acagctgttg tcttttgatt aatcaccccg
    37141 atagctgcct catcagcaat catggctgca atggtttcag acggtgtctc ctctgggatc
    37201 gcaatcatat ccaaaccaac cgagcaaatg gcagtcatgg cttctagctt ttcaagatta
    37261 agcgagcctc cctgcactgc tgcaatcatg ccctcgtcct ctgatacagg gataaaggca
    37321 cctgacaacc cacccactcg gttgcaagcc atgacaccac cctttttgac tgcgtcatta
    37381 agtaaagcta gggcagctgt cgtgccatgt gtgccaacta tttcaagtcc catctcctct
    37441 aagacacgtg ccacagagtc accaactgct ggagtgggag ctagcgacag atccacaaca
    37501 ccaaagccca cacctagccg ctcacttgcc atctgtccca ctagctgacc gatacgcgtg
    37561 attttaaagg ccgttttttt gacggtctcg gctagaacgt caaagctttc accacgaacc
    37621 ttttccaagg ctcttttgac cacaccaggt cctgaaacac caacgttaat caccgtatcc
    37681 gcctcaccga caccatgaaa ggctcctgcc ataaaaggat tgtcctcaac agcattagca
    37741 aagactacta gctttgctgc ccctatctca gaggctttgg cggtttcctt gatgatacgc
    37801 cccatgtctg caactgctgt catattaata ccagaccttg ttgatccaac attgaccgaa
    37861 gcgcagacct tctgtgtttg agccaaagcc tgaggaatag actcaatcaa aatcttatca
    37921 cccttttgat agcctttttg cacaagagct gaaaagccac cgataaagtc aactccgata
    37981 tcacaggcag cctgatccag agcttttgca agcgacaggt agtcttctgc gtctgttgcc
    38041 gccccaataa gggctatcgg agttacagag acgcgcttat taacaatggg aatacctagt
    38101 tctgctgcaa tgtcatcacc aaccgccaca agattagctg cctttgtcgt aatcttttgg
    38161 taaatcttag cggcagctct atcaatatcc gaatcaatac aatccagcaa ggaaattccc
    38221 atcgtaatgg tacgaatatc aaaatgctgc tcctcaatca tctcaactgt ttcacgaacc
    38281 tgtctaatat ccatagtcat caagctcctt atatgttatg catagcatca aaaatcgctg
    38341 cgctttgaat attaatcgtc acctgcaatt gctttccata agcctgaagc acctcacgca
    38401 gatgagcaaa atcctgcttt tcactgcttg agacaatggc catcatggta aaataatcat
    38461 ctaaaacggt ctgtgaaatg tcatcaatat ttaaccctaa tgcagcaatt tgtcctgaaa
    38521 cacctgcgac aatcccttga ttgtccttac caacaactgt aatgatagct ttcatggcac
    38581 acctcctcaa tatgtgttat attttatcac aaacaaaaag agaaagctat cagagacaag
    38641 aggtctggta gccccttgca aaaatagaac aatgggtacc agaaaaaaga gtttgttatc
    38701 caattgatac cgtttattaa tatttagact ttataatata atagcagcta ataaaagata
    38761 agacgtttga agctgccaaa aaagctgggt ctaaggaagc ccagcttttt tgtaggttaa
    38821 ttaagggata gcagaagatt agtcgggatt gtaagaatag ccgtatcctc tcttaccacc
    38881 tctatcagct agaccatcta aatagccatt tccataatta tcattatacc cttgactata
    38941 gtcattatat tcctttggac tagactcatc aaaccgctta ggataatctc ctttgtgctt
    39001 tttgccacca tatccatcct catagccaac tcggtaacca tcacgacgac catgattgta
    39061 ggggtgttcg tctttaagtt ttggtgattc atcattttct ccgcttaagc ctttaccgtc
    39121 taaatcttcc tttggcttat tctctccatc taatcctttt aaaggatttt tacgattatt
    39181 tccttctaaa ttcggagttg atgggggacc ggcttcacct cgttcacctt gctctggttc
    39241 cttctgattc tcaccattca agcctggaag cgaaggacgg ccttgattat taccactcaa
    39301 ccctgaaagt gggggaccag cctcacctcg ttcaccttgc tccggttcct tctgattttc
    39361 accattcaag cctttttctg gcagcttggg actattgccc tgaggctttg gttgaggctg
    39421 cgggctagaa ttatccttac ctagatctaa gtgctgtggc tttccttgtg gctgatggtg
    39481 atgacctgaa ccagagctgt tacctcctct cagccccagt ggctgggaag gcccttgatt
    39541 aggaatagcc tgaggctctg aggcctgtcc actactattt ccttggctgt tcacactgag
    39601 agactgaggt tgattcccat gatgacctga gctctttgct gtcggctggg acgggctagt
    39661 agcctgatgc tgatgattag taggctgatc tgaaggctta ggctgcaagt tatccttttt
    39721 cggtggccga ctgaccattg aatctgatga gctcttgtgc gacttatcgt catctccaat
    39781 cgagctgact ggctgctcct ttggcctcgc ttgatgggat gagccaccaa gacttcctaa
    39841 taaacctcca aagacaagtg cagctcccag cagcaagctg gtcaccactg caccggcaaa
    39901 tagccattgt tttttggact tccatgtgcg aaaacgtcct tctgtttttc tcatactttt
    39961 ttaactctct ccatattttt tggtaaaaat accaagaaat agtatatata gtcaagactt
    40021 tatcatattt cttttaaatt tttatcatct gatatattcg attgttttta caaatctgat
    40081 aaccaaaaaa tcctcgtatc atactgatac aaggattttt atatatttga acgtcacaag
    40141 tactcctggc ttattgtttt ttgccaaaga gcgctgaagc aacaattatc acaatagctg
    40201 ctcctagaat tgaagggaaa acagccatgc ctgccagctg aataccccag tcgccaaaca
    40261 gcttttgacc aactgcagag cctatcaaac cagcagcagt cattgtgaaa cagcccatcg
    40321 aatggctttt ttctgttatc ctacctgcaa ccatgccgat aatagctcca acaattaatg
    40381 accaaaccat cgcaaatctc ctttatgttt tgtcttatta taccataccc ttgccttata
    40441 tcagtcagat gatggtggtc gcttgatatt aagagcaagc tgcttttttc tcttagtaag
    40501 caataagtct ctcagcgata tcacaagcac tgctattaaa atcaaggcca ttcctaacag
    40561 atcaataggg tgaaaaatct ctttcatcag gataatcgca aagcagacag aggcaaccgg
    40621 ctcaattgaa gccagcaagg tagccttgat cggtccaatg attgaagccc cctttagaaa
    40681 aaaggtgtag gcaaaaattg tcccaatacc gataatgcca aacagggccc gtagattccc
    40741 ataagtcatt gccaatgggt actgccatgc tcttgtcagg atcggaaaaa tcactcctcc
    40801 catcagcatg gcaagaccaa caatcagcaa gctcccccag tcggcaatca gcttagcagg
    40861 cttgatgaca cagtaagcat aggtcaccgc tgcaaaaagc ccccagaaaa gtccaatagg
    40921 attgattgcc agatgggaaa gatcaccatg acaggccatg ataaccgttc ctaggatcgc
    40981 taggcaaata gcacagctct ctcccacagc cggcaggcgt cttgatttga acgataggta
    41041 gaccagcacc aaaatggggg aaaggtattg caggactgtg gctgtaccag cattagagta
    41101 acgaatagca agcagatagg catattgatt aagtgtgaga ccaaatagac tgtaaatcaa
    41161 cagctctctt aaaagccttt tgtccttgag taagctgatg acagcctctc tttgccgcac
    41221 ataagccata gctgacagca caagccctga aataatgagc cttagtgagg tcaaggcatt
    41281 gatgccgacc ccatgagcaa ttaaatattg ccctgacacc cctgagagac cccaggcgat
    41341 tccggctagt aaaatcatgg tactgccttt tccatttctt gacatattat cttcctcttt
    41401 ttaatccatg ccatgataag gccactcata ataccttgat agctctagcc tagacttcac
    41461 caagcctgct taacagtcat taacaacaga ccgataagct acctcttaca gcttcggata
    41521 gcgaggtatt atcacagaat tgtcctaaag agcctaccat cataaagagc ctgaaaactc
    41581 tgtttcagac tcaatgccag tcataacgac tccttaatcc agcaattttt gcaattcttg
    41641 ggctaacaat tgctgagcta tctgtgggtt ggcttgcccc tttgtggcct tcatcagaaa
    41701 accagtaaag gccttgtcag cattgcgctt gcctgatttg aaatctgcca cagcagcctc
    41761 attgtcagca aacacctgat gaatgattgg aatcaagaca gctgggtctg aaatttgaac
    41821 caagccggcc ttttccacat aagcacgcgc tgagccgcca tgctttgcca aatgaacaaa
    41881 aaccttcttg gcgatttttg atgaaatcgt gccatcagtg atgatcgcaa tcatttccac
    41941 gagattttct ggggtcaagg caatctgatc aatcgtcttg ccctcagcat ttaagaattg
    42001 agccatctca ccctgaagcc aattagacac ctgcttagga tcaccaccaa gtgccacagc
    42061 ctgctcaaag aaatcagaca aagcctttgt tgctgtcagc tgacctgcat cataggctga
    42121 caagccaaga gcattaatgt agctagctcg cctgtctgcc ggaaatcttg gaagctctgc
    42181 acgcatatcc tcaatccatg cgtcatcaat ctcaaacaat ggcaaatctg gctctgggaa
    42241 atagcggtag tctgctgctc cctccttgac acgcatgaga atcgttccct tacttgcctc
    42301 gtcataacga cgtgtctcct gacgaataac accgccagag cgtaggattt tggcttgacg
    42361 ctccacctca aactcaagcc ccttacgcac attgctaaat gagttcaggt ttttcaattc
    42421 tgtttttgta ccaaaggcct cttgtccgta tggtcgcaag gagatattgg cgtccacacg
    42481 catggacccc tcttccatct tgacatcaga aataccagta tactgaatga tttcctttag
    42541 ggcagtcagg taagcatagg cctcctctgg agagcgcatg tcagcctctg agacgatctc
    42601 aatcaagggc actccctgac gattgaggtc aacataggaa taaccatctg taccatgcgt
    42661 atttttgccg gcatcctctt ctaggtgagc acgctcaata cggattttct tggttgagcc
    42721 gtcctcaaga gtaatatcaa tccagccatt gtagccaatc ggctcatcaa actgtgaaat
    42781 ctgataggcc ttgggattgt ctgggtagaa ataattctta cggtcaaagt gcatgtgctg
    42841 atgaatagac atgttaagag caagtgctgc tttgattccc gcatcaatga ctcccttgtt
    42901 catcactgga aggacacctg ggaaagacca gtcaatcaca ttagtgctgg catttggatc
    42961 ctctccaaaa tgagctgatg aaggtgagaa aatcttagaa ttggtattca actccacatg
    43021 gacctcaagt ccaataatgg tttcaaaatt cattacctgt cacctccaaa aatcataggc
    43081 tgctgcttgt ggtagtcagt agtcgcttca aaggctaccg ctacctgata gatgacctct
    43141 tcgctatatt ttggaccgat caattgaagc ccaacaggca agccatctgc aaagcctgct
    43201 ggaatagaga ttgcaggcaa gcccgctaga ttcaccggaa tggtcaaaag atcagccaaa
    43261 tacatggcaa caggatcatg attcaacgta tcaagctcaa aggctgctgt tggtgctgtt
    43321 ggtcctaaaa tcaagtcata atcagcaaaa accttctcaa agtcttgaat gatcagcgtc
    43381 cgaacctgac ctgccttttt gaaataagca tcgtaatagc ctgatgataa gctaaaggta
    43441 ccaagcatga tacgacgctt aacctcatca ccaaagccct gactacgcgt cttgacatag
    43501 atgtcctcaa ggctcttggc atcagcagca cgaaagccat agcgaatacc atcaaagcgc
    43561 tgtaggtttg atgaggcctc agatgaagcg atgatataat agacagccac cccatacttg
    43621 ctatgtggca gactgacctc ctcaatgata gctcctagct tctcaaaatg cttagcagca
    43681 gccaaaaccg tctccttaat cttaggatca atgccttcgc caaggtattc cttaggtagt
    43741 gcaatcttca tgcccttgat gtcttgaccg atcttaattg tgtagtcagc gatctgtaca
    43801 ggtgctgagg ttgagtcctt gcggtcactc cctgcaatga ccgatagcag ctgggcattt
    43861 tctcttaccg ttggcgcaaa aggccctatc tgatctagcg agctgccaaa ggcaatcaag
    43921 ccatagcgag aaacagcccc ataggtcggc ttaagcccaa caacaccatt aaaggctgct
    43981 ggctgacgaa tagagccgcc agtgtctgag ccaagagata agcgaacctg acctgaagct
    44041 actgctgttg cagagccacc tgatgaacca ccaggaaccc tgctatgatc ccaagcgttt
    44101 ttggttttct tgaaataaga cgtttctgtt gagccaccca tagcaaactc gtccatattg
    44161 gtcttaccaa taacaatcat atccttgtcg taggcattag ctaccgctgt cgcatcaaaa
    44221 atcggctcat aattataaag catcttagaa gcagcagttg tcagaatccc cttggttgag
    44281 atattgtcct tgacagctag tggtattcct gacatcacat tgtcaggatc aatcccctta
    44341 gcatcaagtg cagcagcctg ctttaaagca gcctcgcaag caatggtaat gaaagaaccc
    44401 acagcctcct cacgcgcctt gatatcctca agggttgcct ttgttagctc aactgcagaa
    44461 atgtcctttg caacaagaag ctcatgtaat tcttctatag tatgatgatt aaaagacatt
    44521 aggcatctcc tccgtcatca agaatagctg gtaccttgat gaaatgattt tctttttcag
    44581 gaacattttg aaacaggagc ttgcgatcca ctccagcctc agcgatatca gctcgcatga
    44641 tatttttctt gtctgccatt gtggtggtaa tggcaacacc tgtcgtatcc acttcattta
    44701 gcaattcaac catgtcaacg atttttgata atgttgtcgc aaactcagtt gtttcacttt
    44761 ctgaaaagga tagctttgat agggccgcaa cgtggcgaac ctcttcttca gaaattttca
    44821 tgaattctcc tatccaaggt aaagcagacc atcatcagcc acaaggcctt gctgtttcaa
    44881 acgcttgata atagcctgaa taacccaatt ttacatagtc ttaaccatta tatcataatt
    44941 agctttattt accatagcgg actgctggga tttcacgtca aatgcatgtg gcaactgacg
    45001 ttttctgata acgtttttca taagctcaac ctgctttttt caagaacagc caggctataa
    45061 ctaaactgca tttgagcaat tgatgaggtt aaaagggcaa tgtggctaga gcatagctac
    45121 ctgcatttta ttcacgtgta tgcgtagctg ggattagcga aaaacttaat aacaaaaagc
    45181 ctcctagcca agaccaaaag atctcactaa gaagccctta agatcagcgc tgagccaagc
    45241 agcagctaat actgccttac ttgattagcc tatcccagct gatcgaacga tcgcctaaga
    45301 aagccgatca agaagctttg ctcctaggac agtcctacag tggttcagcg cccactggtg
    45361 attttctgtt gaattgctcg ccactgctga tgtgataatc tcaagcttgt agcccaattt
    45421 ataggcatca atcgctgtat gaaggacaca aatatccgtc agcacacctg tcaagaccag
    45481 cgtcgtgacg ccacgctcac gaagacgaat atccaaatca gtccccgaaa aggcagaata
    45541 atgccgctta tccagccaaa agacccgctg atcttgctgg tatctggtat atacggtcat
    45601 caaaggacca tacaggtccc gaccccttgt cccgataata ttatgcggcg gaaacaaggc
    45661 tgcctccgga tgaaagctat ctccctcctc gtgggcatca atcgcaaaaa agatatagta
    45721 gccggcctca aaggcagcct caacaacgct agccatcgcc tctgaaatca cctgagcagg
    45781 tgctcctgcc gtcaggctac catcatcagc tacaaagtca ttcgtgtaat caatagaaat
    45841 caaggccttc acagcttatc cctccccaaa aagcttatgc tctcttagct gcatgacagc
    45901 aagccataag aactaagcct gcttttaata ttcagtatga ttagacactt atagtttacc
    45961 actaaacacg acagctgtca agacagcgga ttgatttata cacgataaag gcgaaaaaca
    46021 gttatttctg aactatagta tagatttaag tagacacttt caacgttttt ctatatgaaa
    46081 ataagatata ttcctgaaat agctgaacat tgaaatacag aaagccttat tttcttgcta
    46141 aaaatctttc atgcatctgt catgttcatc tcatgctgaa tcacagcgaa aatacaaaaa
    46201 atacccctca aaagccagcc aatgctagaa cctttgaggg gacgctataa taatgtgtga
    46261 agtcctccac agctgctaag aaactccgat aagccgtcat aaagaccaag tctagccctt
    46321 accaagcagg gctctggcta atgaatggct gctctataag cagcaagact ttgatcatag
    46381 ctaacacttt cactacctgc tctgactaat cacagctagc aaagctaaag gcaagccttg
    46441 ggcttagcag acgatcgcat ctgagctatt aaaattcctt tagcttgtca aagatgcctt
    46501 cgttaatcac cttgagataa gtgcctttca ttcctagaga gcgactctca atgatacctg
    46561 cactctctag ctttctaagg gcattcacga tgacagatcg tgtgattcca atacgatctg
    46621 caatcactga agcggtcagg cgtccttcat tgccatctag ctcactaagg atagctgcaa
    46681 cagccttcat ttcagagtaa gatagagtgt tgattgccat attaacaact gtctgcttac
    46741 gaatggtttc ttctaggttt tctgtttgaa gatttaacag ctgaataccg accacagtgc
    46801 ttgagatttc aactaaaaca aggtcatcat cactgaattc attgtcgtta cgccagatga
    46861 tcaaggtacc taagcgcatg ccgccaccat agataggggc aatcgtggtt aaaccatcag
    46921 gatagatatc ctttgactca ataggaaaaa tcgttagttc attttccaca gaaaggtttg
    46981 cttcagtgtc ataaacacga ctagctgcct tgacataagc atctgggaac tgtcttgttt
    47041 caaaaaattc ctcgacgcgg tctgtgttgg tcttgtactt catcgcatag ccaagtaagc
    47101 tgccgccacc attgatgata caagcattac aatcaataat atctgctaag cgtgaagcca
    47161 tagtgttata ggggagttct gtttccaagc tgtctacaga acgttgcaaa atagaagtaa
    47221 tcttacgggt tttttctaat aaatttggca ttttttcttt tccttttaat tatttgcgtt
    47281 acaattatat caaaggaccc tagcttttgc aaggaattat cagaaaattg gctattatac
    47341 ctacaattcg gatgaggcca gagccttatt ttgctgaaaa acaaaaagga tctcgcgatc
    47401 caatttttgt atgagaatca tattagcgct tgtattgctt gagaacatgc gtgatctttt
    47461 cttgcacgtc agctagctct tctactgttg gcagatagac cacgcgaaaa tgatcaggct
    47521 ccttccagtt gaagccacgc ccatgtacca gcatgacctt ttcttgcttc aaaagctgta
    47581 ggacaaattc ctcgtcgtca tcaatgcggt acatatttcg atcaattttc ggaaacaaat
    47641 agaggcctgc cttaggcttt acagctgata ggcctggaat ggcattaatg gcctggtaaa
    47701 tgaagttacg ttgctcaaag atgcgaccac ccggaagcaa gagctcatca acagactgac
    47761 gtcctcctaa ggaggtctgc accacctgct gcgctaagac attggagcac aagcgcatgt
    47821 ttgccagcat gttcaagcct tcaatgtaac ctctgacatg tcttttaggg cctgacaaga
    47881 ccatccagcc cactcgaaag ccggcaatac ggtgtgattt tgacagccca ttcattgaca
    47941 cgcaaaaaac atcaggtgca aggctggcaa ttgcgatatg ctccccaccg tccatgacca
    48001 aacgatcata aatctcatct gcaaaaatga taagctgatg ctctctggca attgcaacaa
    48061 tctcctctaa gacctctcga gggtagagag cacctgttgg gttattggga ttgataatga
    48121 cgatagcttt tgtgcgctca gtgatcttgg cttttatgtc agcaatatca ggataccatt
    48181 cagcctcttc atcacacagg taatgcaccg catgcccacc acctaggctg acacaggctg
    48241 tccaaagggg atagtcaggc attggcacca gcacctcatc accattatcg agcaaggctt
    48301 gaagagacat cgaaatcagc tctgagacac catttcccaa ataaatatca tcaatgtcaa
    48361 catcaggaaa gccctttagc tgacaatatt gcatgatggc cttacgagct gaaaaaatcc
    48421 ccttgctatc agaatagccc tcgctggagc gagcattgag aatcaaatca cgaataacct
    48481 catctggagc ctcaaagcca aaggctgctg ggttacctgt atttaatcga aggatctttt
    48541 caccattagc tatcatacga ttagcctcgt ccaggactgg acctcgaata tcgtaggcta
    48601 cgtgttctaa ttttgatgat ttttcaatta ttttcatagt ctcattacct cgtaacccat
    48661 attataaacc aaaacaatta aaatagaaag cacttttcta tgagcttaaa gaatgccaaa
    48721 agctcaacca aagctctaag caagctaagc agcagctatt aataaggcta tctaagctag
    48781 cttctagctc aaggtatcct cacctcaggg aatagctggg ctatttggtg aacaatagct
    48841 cagaaaatca ttaaaacgtt ttcaatttct cctcaaaaaa ggtataatag ctatagagat
    48901 aaagttcaaa ggaggataaa ccgatgtcac aaacatatga acgtatcatg gtcgctattg
    48961 atggctctca tggctccgaa ttagcctttc acaagggggt taatgtcgct ttgcgtaatg
    49021 gtgctgcctt gattttgacc catgttgttg atacacgtgc gctgcaaagc gttgcaacct
    49081 ttgatagcta catttatgac aagttggagc agga
//
LOCUS       DARYVE010000009        48974 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYVE010000009 DARYVE010000000
VERSION     DARYVE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48974
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(79..549)
                     /locus_tag="TVW25_000443"
                     /pseudo
     CDS             complement(79..549)
                     /locus_tag="TVW25_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            764..985
                     /locus_tag="TVW25_000444"
     CDS             764..985
                     /locus_tag="TVW25_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1378113.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1015..1308
                     /locus_tag="TVW25_000445"
     CDS             1015..1308
                     /locus_tag="TVW25_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1378114.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2445..4277
                     /gene="lepA"
                     /locus_tag="TVW25_000446"
     CDS             2445..4277
                     /gene="lepA"
                     /locus_tag="TVW25_000446"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1378115.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4819..5256
                     /gene="msrB"
                     /locus_tag="TVW25_000447"
     CDS             4819..5256
                     /gene="msrB"
                     /locus_tag="TVW25_000447"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1378116.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5544..6563
                     /locus_tag="TVW25_000448"
     CDS             5544..6563
                     /locus_tag="TVW25_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1378117.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            6907..7332
                     /locus_tag="TVW25_000449"
     CDS             6907..7332
                     /locus_tag="TVW25_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1378118.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7347..7838
                     /locus_tag="TVW25_000450"
     CDS             7347..7838
                     /locus_tag="TVW25_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1378119.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            7856..8665
                     /locus_tag="TVW25_000451"
     CDS             7856..8665
                     /locus_tag="TVW25_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1378120.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8662..9489
                     /locus_tag="TVW25_000452"
     CDS             8662..9489
                     /locus_tag="TVW25_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1378121.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGIVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9679..11313
                     /locus_tag="TVW25_000453"
     CDS             9679..11313
                     /locus_tag="TVW25_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1378122.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11317..12102
                     /locus_tag="TVW25_000454"
     CDS             11317..12102
                     /locus_tag="TVW25_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1378123.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12126..13136
                     /locus_tag="TVW25_000455"
     CDS             12126..13136
                     /locus_tag="TVW25_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1378124.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13389..15173
                     /gene="uvrC"
                     /locus_tag="TVW25_000456"
     CDS             13389..15173
                     /gene="uvrC"
                     /locus_tag="TVW25_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1378125.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15301..15903
                     /locus_tag="TVW25_000457"
     CDS             15301..15903
                     /locus_tag="TVW25_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1378126.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            15984..17393
                     /gene="pepV"
                     /locus_tag="TVW25_000458"
     CDS             15984..17393
                     /gene="pepV"
                     /locus_tag="TVW25_000458"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1378127.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17660..19036)
                     /gene="mnmE"
                     /locus_tag="TVW25_000459"
     CDS             complement(17660..19036)
                     /gene="mnmE"
                     /locus_tag="TVW25_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1378128.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19308..19529
                     /locus_tag="TVW25_000460"
                     /pseudo
     CDS             19308..19529
                     /locus_tag="TVW25_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            19652..19966
                     /locus_tag="TVW25_000461"
     CDS             19652..19966
                     /locus_tag="TVW25_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1378129.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            19971..20303
                     /locus_tag="TVW25_000462"
     CDS             19971..20303
                     /locus_tag="TVW25_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1378130.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            20305..21903
                     /locus_tag="TVW25_000463"
     CDS             20305..21903
                     /locus_tag="TVW25_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378131.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            21897..22583
                     /locus_tag="TVW25_000464"
     CDS             21897..22583
                     /locus_tag="TVW25_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378132.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            22605..23291
                     /locus_tag="TVW25_000465"
     CDS             22605..23291
                     /locus_tag="TVW25_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378133.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            23313..23990
                     /locus_tag="TVW25_000466"
     CDS             23313..23990
                     /locus_tag="TVW25_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378134.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            23997..24311
                     /locus_tag="TVW25_000467"
     CDS             23997..24311
                     /locus_tag="TVW25_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1378135.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            24759..25442
                     /gene="rpiA"
                     /locus_tag="TVW25_000468"
     CDS             24759..25442
                     /gene="rpiA"
                     /locus_tag="TVW25_000468"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1378136.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            25520..26731
                     /locus_tag="TVW25_000469"
     CDS             25520..26731
                     /locus_tag="TVW25_000469"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1378137.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKSLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            26944..27753
                     /locus_tag="TVW25_000470"
     CDS             26944..27753
                     /locus_tag="TVW25_000470"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1378138.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            27844..28629
                     /locus_tag="TVW25_000471"
     CDS             27844..28629
                     /locus_tag="TVW25_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1378139.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(28762..29670)
                     /locus_tag="TVW25_000472"
     CDS             complement(28762..29670)
                     /locus_tag="TVW25_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1378140.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            30010..30459
                     /locus_tag="TVW25_000473"
     CDS             30010..30459
                     /locus_tag="TVW25_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378141.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            31080..31772
                     /gene="pyrF"
                     /locus_tag="TVW25_000474"
     CDS             31080..31772
                     /gene="pyrF"
                     /locus_tag="TVW25_000474"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1378142.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            31832..32467
                     /locus_tag="TVW25_000475"
     CDS             31832..32467
                     /locus_tag="TVW25_000475"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1378143.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            32519..33262
                     /locus_tag="TVW25_000476"
     CDS             32519..33262
                     /locus_tag="TVW25_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378144.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            33497..34951
                     /locus_tag="TVW25_000477"
     CDS             33497..34951
                     /locus_tag="TVW25_000477"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1378145.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            35071..35937
                     /locus_tag="TVW25_000478"
     CDS             35071..35937
                     /locus_tag="TVW25_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1378146.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            35965..36618
                     /locus_tag="TVW25_000479"
     CDS             35965..36618
                     /locus_tag="TVW25_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1378147.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            36749..37156
                     /locus_tag="TVW25_000480"
     CDS             36749..37156
                     /locus_tag="TVW25_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378148.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            37168..37821
                     /locus_tag="TVW25_000481"
     CDS             37168..37821
                     /locus_tag="TVW25_000481"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1378149.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            38053..39327
                     /locus_tag="TVW25_000482"
     CDS             38053..39327
                     /locus_tag="TVW25_000482"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1378150.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(39381..40028)
                     /gene="plsY"
                     /locus_tag="TVW25_000483"
     CDS             complement(39381..40028)
                     /gene="plsY"
                     /locus_tag="TVW25_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1378151.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            40161..42110
                     /gene="parE"
                     /locus_tag="TVW25_000484"
     CDS             40161..42110
                     /gene="parE"
                     /locus_tag="TVW25_000484"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1378152.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            42212..43027
                     /locus_tag="TVW25_000485"
     CDS             42212..43027
                     /locus_tag="TVW25_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1378153.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            43502..45961
                     /gene="parC"
                     /locus_tag="TVW25_000486"
     CDS             43502..45961
                     /gene="parC"
                     /locus_tag="TVW25_000486"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1378154.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            46059..47084
                     /locus_tag="TVW25_000487"
     CDS             46059..47084
                     /locus_tag="TVW25_000487"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1378155.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            47152..47382
                     /locus_tag="TVW25_000488"
     CDS             47152..47382
                     /locus_tag="TVW25_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1378156.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            47443..47523
                     /locus_tag="TVW25_000489"
     tRNA            47443..47523
                     /locus_tag="TVW25_000489"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47477..47479,aa:Tyr,seq:gta)
     gene            47562..47633
                     /locus_tag="TVW25_000490"
     tRNA            47562..47633
                     /locus_tag="TVW25_000490"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47594..47596,aa:Gln,seq:ttg)
     gene            47761..48963
                     /gene="rpsA"
                     /locus_tag="TVW25_000491"
     CDS             47761..48963
                     /gene="rpsA"
                     /locus_tag="TVW25_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1378157.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        14079 a         9085 c        11440 g        14370 t
ORIGIN      
        1 agaattatcg caaaattatg atagcgtcgc tgataaaatt cagcacttct aaacagattt
       61 ggattcatga atatctcctt acttactaaa taaatgatga tagaagcctt gatgcgtcat
      121 taattcgtta tgcgaaccta tctcgattat ttttccttta tcaagtacaa caatttggct
      181 agtacgttca gcagtactaa gacgatgggc aacgaaaata atcgttttct cggtcattga
      241 cattaggtta tcaatcactt ttttctccgt taagacatct agtccgcttg tcgcctcatc
      301 gagaattaga ataggagact tggttaataa tgctctagct aatgcaattc tctgtttttg
      361 tccaccagaa aatcctgccc catcagatag ttctgtctga tagcccatag gcatttgttc
      421 aatatcttct ctaatttctg ccatatcaca ggcattgata atatcctctt gagtaatcgc
      481 ttggtttgca ccgagagtaa gattttctaa aattgatcca ctaaaaatat aagcttgttg
      541 aggcagatat tggttatcga aacgtcctaa atggtaatct gacaaatcta tcaaattatc
      601 tcaaacggtt gaatttaagt cttaagcggt aaatttttcc catttaggac gtttcgatga
      661 ctgtttagga aatggagaac aaattttaac cgaaagtgtt atactaagtc tgtcaagctt
      721 gcaaccggac aaaataaaaa cacatataaa ggaggtattc gtcatggata caaaatttac
      781 agcgttgact gaagagcaat tgaaatcagt tgagggtgga aaaaatggag ttgtaaaatt
      841 acctggaggg accggtgtat attgttggaa tacaggaaaa aatagtgcaa aatgtggtat
      901 ggactggagt gtggcaggac catatgttgg taagataatt gtcaatggtt gggttaacca
      961 tggaccttgg gcaagtcgtc cataatttta atttatatag agaggtgtga aatcatgaat
     1021 gaaagagatt tagtacagct gatagaacag actctaaaag atgaagaggt gcaaaataat
     1081 gtcacttata ggaatctttt ggaagaaagt ctccagcaat tatcactcaa aaagcctgtg
     1141 tatttagtta gtaccaggtt agcaggacat atttcaacct atctaatgac aaatcattat
     1201 gaggcaccaa aagcgattat agttcttgct caatctatcg catcaacccc agctaaacat
     1261 agaggtttaa tttctatacc attctggtta agtaatatat ttcgttaaaa aatattttca
     1321 gatcaggatt tagaaggagt tgtagattgg caatgcactc ataaaataag acacattttt
     1381 tggagttttt tgcttgaact cctaactttt acattagtct ataaacagtc aaaggaagtt
     1441 ctttcaatct ctcaaattgc aaaacaattt tggctatatt ttaaaagtac aattttgatt
     1501 ccaattttag ttacaatcat tcttataaag gagattttgt caagtacatt acaaataatg
     1561 atttattttt accttaatgt tgttgtcatg tgctacgcta ttggaatgat cttatcgtta
     1621 ggttatgtga tttcacccaa gcactctata ttcaataaaa ttaaaaatat aaaattaaat
     1681 aatagagtat cccaagagat tgccgaatcc caatttacca gtcttttaga gcgaagagcg
     1741 acttgaagaa actgataaat ttatttggtt ttctgctaaa aatcctgcca aaaaatcttt
     1801 ggcaggattt ttattttact aagagatatt taggagtggc tttgtcattt aatgcagatt
     1861 atgatatagc aggagacata ttgttgaagc tgtctatgtc acttttggtg gcaggtaggt
     1921 cttattggaa ttggtgactt atgacattta tcggtggctg taagcgtttg actttttcac
     1981 gtttcatagt ggtccgctct ggaatgagtg ggtatttttt cagaatatga tcaaagatag
     2041 atgacatgtt ttacagcagg ctatagctgg tatgatttgt ttaaaaaatc aaggccaatg
     2101 ataagtgctg ggtgacataa gtcttatggc tttacttctt gttagcttgt gtcagcaggt
     2161 gctgagtcaa tcgttgtagg aattatcgta aacctaacag tagctgctgt tctatttgtt
     2221 tattttctgg tttctattca aatttctaaa atgctagggt aacaaatatg aaacaagcaa
     2281 gtggcgtact gcgaacagct tgataactta ttgcctgctt aaagagggtg ctgttatgct
     2341 tggttttatt aggcttatgg catgggatta aaaggttgct gtagcgccat tgtcattatt
     2401 ttggtacaat aataggtaaa agactaaatg tataggaaaa tagaatgaac agtcaagaat
     2461 taaaaaaacg tcaggagaac attcgtaatt tctctattat tgcccacatt gatcatggta
     2521 agtcgactct tgctgaccgg attttggaaa agacagaaac ggtttcaagt cgtgaaatgc
     2581 aggcacagct ccttgattca atggacttgg agcgggagcg tgggattacc atcaagctaa
     2641 atgcgattga gctgaattat aaggctaaga atggtcaaga ttatattttt cacttgattg
     2701 atacaccagg gcatgtggac tttacctatg aggtgtcccg gtcactagct gcctgtgagg
     2761 gtgctgtttt agtggtggat gctgctcagg ggattgaggc acagacccta gcaaatgtct
     2821 atctggcgct tgataatgat ttggaaattc ttccagtgat caacaagatc gatttgccag
     2881 cagctgatcc tgagcgggtt cgtcaggaaa ttgaggacgt gattggtcta gatgcttcgg
     2941 aggctgtact tgcctctgca aagtctggga ttggtattga agatatttta gagcaaattg
     3001 ttgaaaaggt tcccgcaccg tctggtgatg ttgatcaacc gctgcaggcc ttgatttttg
     3061 attcggttta tgatgcttat cgtggggtta tcctgcaggt gcgtgttgtc aatggtatgg
     3121 tcaagccagg tgatacgatc caaatgatgt caaatggaaa aacctttgat gtgactgagg
     3181 tggggatttt tacccctaag gctattggta gggattttct tgctactggt gatgttggct
     3241 atattgcggc ctcaatcaag acagttgctg atacgcgtgt cggtgatacg gtcactctgg
     3301 ctacaaatcc tgcagcagag cccttgcatg gctacaagca gatgaatcca atggtgtttg
     3361 cagggattta cccgattgag tctaacaaat acaatgatct tcgtgaggcc ttagaaaagc
     3421 ttcagcttaa tgacgctagc ttacagtttg agcctgaaac ctcgcaagca ttgggctttg
     3481 gttttcgttg tggctttctt gggctgttgc acatggatgt cattcaagag cgtttggagc
     3541 gtgaattcaa cattgatttg atcatgacag ctccgtctgt tgtctatcat gttaatataa
     3601 ctgatggtga catgcttgag gtctctaacc cgtcagaatt tcctgatcca actaaggtag
     3661 atagtattga ggagccttat gtcaaagccc agatcatggt gccgcaggag tttgttggtg
     3721 ctgttatgga gttggcccag cgtaagcgtg gagattttgt gacgatggat tatattgatg
     3781 acaatcgtgt caatgtgatt taccatattc ccttagctga aattgtgttt gacttctttg
     3841 ataagctgaa atcatcaacg cgaggctatg ctagctttga ctatgaaatt gctgaatacc
     3901 gtcgctcgca gctggtgaaa atggatattt tgttgaatgg tgataaggtt gacgctctta
     3961 gctttattgt tcatagagca tttgcctatg agcgcggtaa gctgattgtt gagaaattaa
     4021 agaaaattat tcctcgtcag caatttgagg tgccgattca agcggctatt ggtcaaaaga
     4081 ttgtggctcg ctctgatatc aaggccttac gcaaaaacgt tcttgctaaa tgctatggtg
     4141 gcgatgtttc ccgtaagcgt aagttgcttg aaaagcaaaa ggctggtaag aagcgtatga
     4201 aggctattgg ctctgttgag gtgccgcagg aggccttctt gagcgtccta tcaatggacg
     4261 atgagagtaa gaaatagtga catgttaagt aaggagctgg atcatgcgat ctggctctta
     4321 tgcttgatgt ctcgataggc tagaaaatag ggcttgtgtc atgataggct tgtatgtttg
     4381 agatggtttg gaacataatg actctatcat atctgtagtg gattgacaaa gagccgtaaa
     4441 ccattgatat ttggatagtt aatttcgagt tattctgtag tactctctta aggtctttca
     4501 tatgagcttt tctaatgttg gtttggttgc ttttcatgat aagtcatatg ggattttttt
     4561 ggtatactga aaaaagccta tagcctctac agtggcgtct ccctctacag agatgataga
     4621 gccagagtga ttgttacgat ctggagatgt ggcgctaggc attaatgcag gaggacttaa
     4681 ccagattgct gttaggcttg aaatcttaag ctatattgat tgtcagcttg atttagagaa
     4741 gtctaagttt atggctcaca aatgctcggt ctttttgtta caatagagtt aatcagttat
     4801 ttttataagg agacagctat ggaatctaag gaagagcttc gccagcgtat tggagatttg
     4861 gcttttgagg tgactcagca tgcagcgacc gaaagagcct ttacaggtca gtatgatgat
     4921 ttttttgaga aggggattta tgttgatgtg gtgagcggag aggtgctctt ttcctctttg
     4981 gataaattca attctggctg cggctggcct gcattttcta agccgattca gcatcgtatg
     5041 gtaaccaatc accatgattc atcacatggc atgcggcgtg ttgaggttaa aagccgcgag
     5101 gctggctccc atttggggca tgtttttaat gatggcccta aggaggcagg aggcttacgc
     5161 tattgcatta actccgccgc gctgaaattt atcccctatg atcaaatgga gcaagagggc
     5221 tacgccgaat ggttagggat ttttgataag agctaggaat tgctagcggc caatgaaaag
     5281 gtagagctct tagccaatgc tagtggctaa atcaaagaaa taaaaaggtg gctaaagtac
     5341 atagaaaaaa gaggtaagca gattggcagg tggtcaatct gctttttgtg aggagacttt
     5401 cagcctgctt tgcgctaaaa agtatgaaac caataaacca cctactatgc gggtgtgtgt
     5461 cggtggttag cttaagtttt ttcagttcgg ttttacaagc ttctctaaaa ggactataat
     5521 agctaatgga aaaggagatt catatgctaa catctttaga aaaattaccg ggcgttttac
     5581 tgtgcttgct gttagcactg cctgcctggt atttgggaag cttatttcct attattggag
     5641 cgccagtttt tgctatttta ttgggaatgc tattggcgct tgtctatcag aagcgtgact
     5701 acactaaatc tggaatcgca ttgacgtcca aatatatttt gcagctggct gtggttttct
     5761 tgggctttgg cttaaacgtg acacaggttt tagtggttgg cttgcaatcc ctgccgatta
     5821 ttgtagtaac gattgtgact gccttgggca taagctattt gttcaaaaga tggttaaggc
     5881 taccagccaa gacagctatc ttagttggtg tgggctcgtc tatttgtggt ggctctgcta
     5941 ttgcagccac agctcctgtc attgatgcgc aggacgatga cattgccaag gccatttcgg
     6001 ttattttttt gtttaatatc ttggcggcct tgctatttcc agctttgggt cagatgcttg
     6061 gcttatcaaa tcatggcttt gctatttttg ctggaacagc agtcaatgat acctcatctg
     6121 taacagctac agcgacagcc tgggacgcta ttcaccagtc taatacgcta gatggggcaa
     6181 ccattgtcaa attaaccaga acgctggcta ttattcccat aacacttggc ttatctattt
     6241 accaaaccaa gagcaggcag gcacatacga cagagggttc ctttagcctc agaaaggctt
     6301 ttccgacctt tattgtcttt ttcttgctag cttccttgat aaccaccttt gctgctagct
     6361 taggtctgcc aatggcaatc tttcatcagc ttaagctact ctcaaaattc tttatcgtta
     6421 tggccatggc agcgatcgga cttaatacca atctagtgac cttagtcaaa actggtggta
     6481 aggccatttt gctgggtggg atttgctggc tagcgatcac atcagttagc ttagcaatgc
     6541 aggcagcttt ggggagctgg taactgatga gaatagctgg tgatacgctg ctttatagga
     6601 aaagcaaagc ccttgctgct cctaaaaaag cttgttagag cagctcactt agctgttaag
     6661 tgtggcttgg tggggtgtaa gtaggctcta tcagttagaa aagccatcag aacaaacgct
     6721 atcattaagc tgaagccggg gaaactcggc ttttacgtta tgcagaattg tctacatatt
     6781 gaataggatt atccatttta aaaacgtttt catttgatag aatacaatta tagcttggtt
     6841 attagggtaa acgagattga acttcttatc tggtttagct taagtaaaaa agcagttgga
     6901 ggaagcatga aacgtaaatt tttaattggt agtcatggga gaatggccag tggattgaaa
     6961 agctctattg acattttggc tggtagaggt caggaattac aagtcattga cgcttatatt
     7021 gatgatagtg attatactga gcaggtattg acctttatcg aagatgtagc agctgacgag
     7081 caggcactga tttttacaga tttattaggt ggcagtgtta atcaaaaaat agtaactgcc
     7141 ctaatggaca gtggcaagga aaatatcttt ttgatttcaa atagtaatct tgcagccttg
     7201 ctatcgttga tgtttttaaa gccagaagaa gagctgacaa aagacgagat tgtagcaacg
     7261 attaacgatt ctcaggtgca gctggtggat ctagctccag cgacagccgc agaagatgac
     7321 ttttttaatt gaggaggaaa aatgaaatga ttacacaaat tcgtgttgac gacagattga
     7381 ttcatggaca ggttgctgtt gtttggacca aggagcttaa tgcccctttg cttgtggtgg
     7441 ctaacgatga ggctgctaaa aatgagatta cacaaatgac tctaaaaatg gcagttccta
     7501 atggcatgaa attattgatt cgctctgttg aggactctat caaggttttc aatgatccac
     7561 gcgcagtgga taagcgtatt tttgtcattg tcagctcgat taaggatgct tgccagattg
     7621 caaagcaggt gaaggactta gaggctgtta acgttgcaaa tgtagggcgc tttgacaagt
     7681 cagacccagc aactaaggtc aaattggctt caagcctatt gttaaatccg gctgaattag
     7741 aagcagcaaa agagctggtt agcctgccta acctagatgt tttcaatcag gtactgccat
     7801 ctaatagcaa ggttagcctg agccagctca tcaaataaag aaaggtgtaa tgactatgtt
     7861 agtaccagca acaatggcag ccttagctgt attgatttgt ttcgggggaa attatttaac
     7921 tggccaaagc atgatggaaa gaccgcttgt ggttggtttg gtgacaggat tgctcttagg
     7981 agatatgaag gtcggtatct tgatgggagc gtcactagag gcacttttcc taggaaatgt
     8041 taacattggt ggtgtcattg cagcagagcc tgtaacagca acagctatgg caacgacctt
     8101 taccatcatt tcacatattg atcaaaaagc agctatgacg ctagctgttc cgattggcat
     8161 gctagcagcc tttgtggtca tgtttttgaa aaatgttttt atgaatatct ttgcgccaat
     8221 ggttgataag gcagcagcgg caaaccatca gggcaagctt gtcatgctgc actatggcac
     8281 atggattgtc tattatttga ttattgcctc tatttccttt atcggtatcc tagttggaag
     8341 cggacctgtt aacgcctttg ttgagcatat tccacaaaat ctgatgaatg ggctaagtgc
     8401 agctggtggt cttcttccag cagtcggatt tgccatgctg atgaagctct tatggacaaa
     8461 taagctagca gttttcttcc tattaggctt tgtgttgaca gcttatttga agctaccagc
     8521 agtagctgtg gctgcacttg gtgcagttat ctgtgtgatc agctcgcagc gtgatttaga
     8581 gttagatgct attactaagg gagctatcag taaccaaagc agctttgact ctaaagaatc
     8641 agaagaggag gacttctttg catgagatct caagacaatt taactaaaga agaaagaaaa
     8701 atgctacgct ctgttttctg gcgttcatgg accatgaatg ctagtcgtac aggagctacg
     8761 caataccacg ctgttggggt tatctatacc ttgttgcctg ttatcaatct cttttataag
     8821 acagataagg ataaggcaga cgctcttgtt cgtcacacca cttggtttaa tgcgaccatg
     8881 catattaata actttatcat gggcttggtt gcctcaatgg aaaagaaaaa cagtgaggat
     8941 ccaacctttg acgctagtgc tattacagcg gtcaaggctt ccttgatggg acctatttct
     9001 ggtgttggag attccttttt ctggggtatt ttgagggtca ttgcagctgg tattgggatt
     9061 tcacttgcta gcacaggctc agcgatggga gcagtagtct ttttacttct ctataatatt
     9121 cctgctttta tcattcatta ttatagcctt tatggtggct attctgttgg tgctggcttt
     9181 attaaaaagc tttatgagtc tggtggtatt aagattgtga ccaagacctc aagcatgctt
     9241 gggtcaatga tggttggctc catgacagct tcaaatgtga agtttaagac cattttaaca
     9301 gttgctgcaa agggagccaa ggaagcagcc tctatccaaa attatttgga tcagctcttt
     9361 attggaattg tccctctttt agtaaccatg accgcctttt ggcttttgcg taagaaggtg
     9421 aacattaact ggattatgtt tggcattatg ctattgggta ttgttcttgg tcttttaggt
     9481 atttgctaat aatctcctag catcaaggat aggtaaggca gggacttctt gctttgctta
     9541 tccttttttg tagtgagggc tgctgaaata gccacctgct tgcttaaatg gcttatggat
     9601 ttgttagata gattaagatt ttcttagctt tgagaaatga tttggtataa tagaaggaaa
     9661 taagggaaaa ggctgcctat ggaagaaaga tttaaaaagc gattgcagga tgatatttca
     9721 catcattttt cacaccaatc attgattttg tccattttac tgattggact ctttctcatt
     9781 ttttcattgg cacctcagca aattgggctg tatcaagatt tgaaggctgt tgaacatagc
     9841 tatcaccagc tgattcggca aaataaggcg cttttaacgg agctcaatca gcatattctg
     9901 accaaatttg tgaatcatca gctgagctct tctgacctta gcaaacaata ttatcaccta
     9961 agaaaccgct cacaaagcca atcagagctg ctggtttttg atgctaacag tcacatgctg
    10021 tttgctagta atcagcatct gggaaatttt tttcgcaatg ctgtctatat gacagaagtc
    10081 ttaaaaaaag caaggcaaag gagtagcttc ttgaggatca gtatggataa tgaggagggg
    10141 cattatttac tgctgataaa gcctattaag atagatcatc aggttaaggg ctattcgctt
    10201 cttgtgatga atggtaagga ttttcttcag ctatcacatc agattgcttc agattttgtg
    10261 attgcagatc agtttgacaa tagctttgcc tttaccaatc ggacctttat gacctcaagt
    10321 ctgaataagc ttgacagtca ttttcttaag ggctatttta tctttcacga gcatcgtgcc
    10381 tttatcctaa gaaaggtcgc tcttagtcct tctatcactc tttacagcta ccgccctttg
    10441 attccagttt ctattgcact cttgttttca ttgatgtcct ctgtcatgat ttatgctatt
    10501 ttgtattgga agtctaaggc tctggcgacg cagattgctt ctagcaattc agcagcgatc
    10561 aatcagatga ttcttgatat gcaggccatc tcaaggcagg aaaaaaatgc cattgacctg
    10621 caaagtcaag atgaatttca atacctgtcg gttcagatca atcagatgat tagccgattg
    10681 caggcacttc atcagaagac cctagcctta gaaaagcaaa atgtgagttt tgaaaaacgc
    10741 atgctggaag cccaatttaa ccctcatttt ctctataata cacttgaaac aattttgatt
    10801 acaagtcatt atgacagtga cctcacagaa aaaattgtcc ttcagctaac caggctgctt
    10861 cgctatagct tagacgaatc acaggaggct gtgtgtctgg gagaggattt ggctgtctta
    10921 gaatcctatc tgttgattag ccagattagg tttgaagagc tgcgctacac gatagctgtt
    10981 gaaccagccc tagagaccct aagggttccc aaattatttt tattgccatt gattgaaaat
    11041 gcgatcaaat atggtctgcg ctatcgccat gaccttgtga ttgagatcag cgtgagacag
    11101 cttgctgatg gaatttactt tactgtagca gataacggtc ctggaattag tcaaaaaagg
    11161 caggccgata ttaaagagct cttgcattca gaggattcac atcatggctt ggtcaattct
    11221 tatcgtcgac tcaagcatca atttataaaa gttgaattga tcttttgtca aagagatgag
    11281 cgctttttac taacctatat ggttaaggag taacagatgt ataagctact aattgttgaa
    11341 gatgagcata ttattcgcaa atggcttcgt tatgcgattg attatcatgc gctcaatatc
    11401 cttgttatcg gagaagctaa ggacggtcag cagggggcta agctgattgc agaggctaag
    11461 ccagatattg ttttgacaga cattaacatg ccgattatga ctgcctttga gatgtttgag
    11521 gccacaaaag agcagtccta tgctaaaatc attttgtctg gctatgctga tttcgctaat
    11581 gcaaagtctg ctatccatta tggtgtgctt gagtttttga ccaagccctt ggaaaggcag
    11641 gccttacatg attgcttgct aactattatc caaaagctgc aacagcagtc tcaagagcag
    11701 gagctaagcc agcagcagga ttacctcaaa ctgccacagc ctaatgacca attgcctgat
    11761 gttgtccaag aaatgctcag ctggatccat gagcattacc aggataaaat catgattggt
    11821 cagttggctc acgatctggg ctatagcgaa agtcacctct atcatttagc taaaaaatac
    11881 ctgaaaatga cttttagtga ctatatcaac caataccgcc tgaatcgagc aattcaattg
    11941 ctgattgctg agccggatgt gatggtttat cagcttgcag aggctgttgg catttatgac
    12001 taccgctatt ttgatcgtgt gttcaaaaaa tatttaggac aaacggtcaa ggatttcaga
    12061 gaaacggtat tacaccagag atcagatagg agttcattgt gacaagaaaa aagctgctat
    12121 tagcaatggc aatagtgata ctaggtgtga ttggctctgg cttgtatgct atctggaggc
    12181 atcaagcagg accagctccc agcaaaccaa gagaattggt tgttttgaca cccaacagtc
    12241 aaaatatcct aacaggtacg atcccagcct ttgaagaaaa atacggcatt aaaatccgtc
    12301 tgattcaagg aggcacaggc cagctcattg atcgcttgca aaaggacaag gaccagctcc
    12361 atgcagacat cttttttggg gggaattaca cacaatttga gagtcataag gagctatttg
    12421 agccttacct ttcaaagcat attggctttg tattgcctga ttacctgctg caaagcgagg
    12481 tcgcaacccc ctatacgctt aatggaagtg ttctcattgt gaataatgaa ttggcaaagg
    12541 acatggttat taccagctat gaggatttgc taaagccaga gctaaaggga aagattgctt
    12601 ttgcagaccc caacacctcc tctagtgcct tttctcagct gaccaatatt ctcttagcca
    12661 aggggggcta cactaacccc aaggcttgga gctatatcaa gcagttgatt catagcatga
    12721 attcaatcaa atctgctagc tcatcagatg tttatcagtc agtagcagaa ggaaagatga
    12781 ccgtcggtct tacctatgag gacccctgtg ttaacctttt aaagagtggt gccaacgttt
    12841 ctattgtgta tccaaaggag ggaacggttt ttttaccctc agcagttgcc attgttaagc
    12901 aatctaaggc caaggctgat gccaaattgt ttattaatta tatgttgtct ttagatgtgc
    12961 agcgggcctt tggtcaatca accagtaata ggccaattcg aaaggacgct aaggccagtc
    13021 aagacatgaa gcctttagat gacattatca cgctaaagga agactatgat tatatcacaa
    13081 gacataaaaa ggatatttta gaacgataca atcaattgag aaagaccact gactaaatgg
    13141 ctttgttata tgaaacagtt catgctgtgc tgcacctgaa tcgttagctg ctttgtctag
    13201 ctttttgagg tcaatctctg cttgggctgt tttttatgtt accataaccc actgcatttg
    13261 tttagaaagt caagcgagat cttaatagcc agttataata ggtctttgag agggagtctg
    13321 agcttgcttg aggtggcaag aagatctgtt ttgacgtcaa atggctgaat ttttggtaaa
    13381 atgatagcat gaatgaactg ataaaacaca agctagagct tttgccagat agtcctggct
    13441 gttatttgca taaggataag gctggcacta ttatttatgt tggcaaggcc aaaaatctga
    13501 gaaatcgcgt acgctcttat tttcgaggaa gccatgatac caagacagag ctgttagttt
    13561 ctgaaatagc tgattttgag tttattgtca caggatcaaa tacagaagca ctcttattgg
    13621 aaatcaattt gattcaagag aacatgccca agtacaatat caagctaaag gacgacaagt
    13681 cttatccctt tatcaagatc actaacgagc catttccaag actattaatc acacgtcaga
    13741 ttaaaaaaaa tgacggcctg tattttggtc cctacccaga tgcttacact gccactgagg
    13801 ttaaaaagct gctagaccgt atttttccct ttaaaaaatg caaaaaccct gttaacaagg
    13861 tctgctttta ctatcattta gggcaatgtc aggctcacac gatttgccat acagacaagg
    13921 cttattggga cagcttggtt gctgatgtca agcagttttt aaacggtaag gacgacaaga
    13981 tcattgatga tttgcgctcc aagatgcttg aagcttcgca caatcaagaa tttgaacggg
    14041 cagctgaata tcgtgatttg atttcaggta ttgccaccat gcgaaccaag caaagggtga
    14101 tgagtaagga cttgcaggat agggatattt ttggctattt tgttgataag ggctggatgt
    14161 gtgtgcaggt cttttttgtc cgtcagggta agctcattca gcgagatgtg aatatgtttc
    14221 cttattacaa cgaagctgaa gaggattttt tgacctatgt cgggcaattt tatagcgacc
    14281 aacggcattt gatccctaag gaggtcttta ttccagagac gattgatgag accttggttg
    14341 cagccattgt tccagcaagg attgtcaagc cgcagcgagg ggaaaaaaag cagctggtcg
    14401 ccttagcaac taagaatgct cgggttagcc ttcagcaaaa atttgatttg ctggaaaagg
    14461 atttaagaaa aacaagtggt gctattgagc atcttggtca gctgttaggc attgaaaagc
    14521 ctgttcgtat tgaggccttt gacaattcaa acattcaggg cacaagtccg gtagctgcga
    14581 tggtggtttt tgtcgatggg aagcccagca agaaggacta tcgcaaattt aaaatcaaaa
    14641 cagtgattgg tccagatgat tatgcgagca tgagagaggt gatttatcgt cgttatagcc
    14701 gcgtgaagca tgaagggcta caggcacctg atttgattat tgttgatggt gggcagggtc
    14761 aggtcaaggc tgctcgtgat gtgattgagc accagctagg ccttagcatt ccagtagctg
    14821 gtctgcaaaa aaatgacaag caccagaccc atgaattgct ttttggtaac cccttggcag
    14881 tggttgagct gccgagaaat tcagaagagt tttttctgct gcatcgtata caagatgagg
    14941 ttcatcgctt tgccattacc tttcacaggc aggtcaggag taaaaatgcc ttttcatcaa
    15001 agctagatca cattgcaggc ttagggccaa aacgcaaaca gctactactc aagcgattta
    15061 aaagcatgac tgctcttgaa caggctagtc ttgaagaaat tcagcagcta gggattccaa
    15121 aaacagtcgc tgaggcactg tttgatcacc ttacctcaaa aagtgaggtc tgaattggcc
    15181 ttgtcaggag ctcaagcagt ctgaattttc ttgacaaaag tgaaaaaata gctgaaacca
    15241 gtttcaaaaa atgatagaat gatactacaa cataaaagaa ttagatagga agcatttgca
    15301 gtgaaatttc tcgaattaaa caaaaaacgc catgctatta aacggtttaa cgataagccc
    15361 gttgattata atgacttgcg aacagctatt gaggttgcca ctctggcacc aagtgctaac
    15421 aatattcagc cttggaaatt tgtcattgtt gaggaaaaaa aggcagagct ggcaaaggat
    15481 ctgccgttgg ctaataagac tcaggtagag caggctcagt atgttattgc cctgttttct
    15541 gataccgacc tcattcagcg ctctcgtaag attgcccgca ttggggtcaa gtccttgcct
    15601 gataacttga ttggttatta catggagacc ctgccgccac gttttgctac ctttactgag
    15661 acccaaaaag gcgaatatct ggccattaat gctggcttgg tggcgatgaa tttggtcctt
    15721 gccttaacgg atcagaaaat ggcctcaaat attattttag gctttaataa aaagctaact
    15781 aatgagattt tagatattga tccacgcttt cgtcctgaat tattgataac tgtggggtat
    15841 agcgatgaca agccagagcc tagctatcgc ctaccagtag acgaaatcat tgaaagacgc
    15901 taagatacac aactactcgt ccagctagcc tataagtttt tggatttagg aggatagcga
    15961 ggcaacacat aaaggagaaa aagatgacaa caattgattt taaagcagag gttgataagc
    16021 gcaaggaagc tatgctagag gatctatcaa acctattaag cattaattcc gagcgagacg
    16081 atgctaaggc agatgccaag cacccatttg gtcctggtcc ggttaaggcc ttggagttct
    16141 ttcttgccat ggcagagcgt gatggttacc aaacgcgtaa tattgataac tatgctggtg
    16201 attttgaatt tggtcaggga gatgaggttt tagggatttt tgcccattta gacgtggtac
    16261 ctgctggtag tggctgggag acagaccctt ataagccggt gattaaggat aatcgtatct
    16321 atgcgcgtgg ttcatctgat gataaggggc caaccatggc ttgctattat gccctgaaaa
    16381 tcatcaagga attaggcttg ccagtttcta aaagggttcg cttcattgtt gggactgatg
    16441 aggagtcagg ctggggtgat atggactatt attttgctca caatggcttg aagaaccctg
    16501 attttggttt ttcaccagat gctgaatttc ccattatcaa tggtgagaaa ggaaacatta
    16561 cagaatacct tcattttgtt ggtcaaaatg ctggagcttt tgtccttcat cgcttccaag
    16621 gcggtttacg tgaaaatatg gttcctgaat cagcgacagc tctgatcagc tcaccgcatg
    16681 agcttaatgt tatcgaagct tctttggagc aattcttatc tgagcacgca gtgacaggat
    16741 ctgtcaaaga ggctgatggg ctattggaag tgaccattat tgggaaatct gctcatggct
    16801 ctacaccaga ggctggtgtt aacggtgcaa ccctgctggc taaattctta aatcaattta
    16861 gctttgatgg cgcagccaag gcttatttgc atattgcagg tgaggtgctt catgaggatt
    16921 tcacagcaga aaagcttggc ttggcttata cagatgacaa aatgggtgcc cttagcatga
    16981 atgcaggtgt ctttagcttt gctaaggatt cagatgacaa taccattgcc ttgaatttcc
    17041 gttatccaaa gggaaccaat gcagcagtgc taaaggcagg gcttgagcaa ttaccaggct
    17101 tgactaaggt taccttatct gagcatgaac acacccctca ctatgtgcca atggacgatg
    17161 agctggtctc aaccctccta tccgtctatg aaaagcaaac aggactcaag ggctacgagc
    17221 aggttatcgg tggtggcacc tttggacgct tgcttgagcg tggtgttgcc tttggtgcga
    17281 tgttcccagg tgatgaaaac acaatgcatc aggccaatga atacatgcca ttagacaata
    17341 tttaccgatc agctgccatt tacgccgaag ctatttatga attgatcaaa taagagattg
    17401 aacaagctct ctgtctaaga tgagccttgc taatattaac gaataaaagc cttatgaagt
    17461 tagtcgttta atgagacttc ataaggcttt ttgtttggcg tcaagccatt atttacaaag
    17521 agaaatgcca cagtggatca tcttttgaaa agtccttgta aaaacagacg taaaactagt
    17581 tttagaggag acattgatag gcagtcatgc ttatcaagag atcttgtcta gcagttatgg
    17641 caaaaagatc agtgaactat tattttccaa ggcagaactg actgaacaat tgagtaatta
    17701 attcatcagg tgcggcatcg cctgtgattt ctcctaggat ttcccaagct ctggtcaaat
    17761 caatctgtaa gagatcaacc ggcattccta aagcaagtcc ttcattgaca gcctctaagc
    17821 tttgtactgc ctgctcaatc aaggaaatat gacgagcatt ggataggtaa gtcgcatctt
    17881 gctctattag cccagtatga tcaaagaaaa tctgattgat ccggtcttcg atcaggtcaa
    17941 tgttttggtt ttgcaaaact gatattggga tcgcctcttc tggaagctgg tctttttcaa
    18001 tgacctgctc cagatcggtt ttattgagga gaataatgcg attgctatcc tgactaaggg
    18061 ctagcagagc cttgtcctgt tcggtcagct tttccgaagc attgagaact aaaaggacca
    18121 gatcagcctc ctgtagggct tttttagacc gctcaacacc aatttgctct actaaatcat
    18181 ctgtttctct aattccagca gtatcaacta gctttagagg aattcccttg atattgacat
    18241 attcttcaat gacatcacga gttgttcctg caatatcagt gacaatggcc ttatcctcac
    18301 gtaacaaggt attgagcaga ctagactttc ctacattcgg tcggccgata atagctgttg
    18361 acaagccctc acgtaggatc ttcccgcgct tggcagtacg taggagctgc tctaaaagtg
    18421 tttgaaattc tcgcgttttg tcacgcaaaa gagcagtggt catttcttcg acatcatcat
    18481 attcggggta gtcgatatta acctcaacct gggctaaggt atttaggatt tcttgacgtg
    18541 tgtcgctgat gagctgtgat agggagccgt ctagctgctt gatagcaata gacatggcct
    18601 tatcagtctt tgcacgaatc agatccatga ctgcctcagc ctgtgttaaa tcaatacggc
    18661 catttaaaaa agcacgcttt gtaaattcgc cgggctctgc cattcgagct ccctgtttaa
    18721 tgaggagctg taaaatgtca tttgtcaccg caataccgcc atgggtattg atttcaatca
    18781 cgtcctctct ggtaaaggtt tttggcgcca gcatgactga taccatgacc tcatcaatca
    18841 cttcacctgt gcttggcttg ataatatgac catagttaag ggtatgtgag gcgactgttg
    18901 ttagatcttt tcctttaaag atcgatttag caatgtccag agccttggta ccagacaagc
    18961 gaacaatgcc aatagctcct tcacctaacg gagttgaaat ggctgcaatt gtatcaaatt
    19021 ctttagttat actcatgcct tctattgtag aacaagtcag catagaaagc aaggtattgc
    19081 attagctgct cgttgtcgtc attcttgtct agtggcaaag cctcaaaagc agttgtaaac
    19141 agctaaagct atgattaaaa agccttgtat ggtaagtaca ggataaagcc aaaaagctga
    19201 tgagttttag ataaacatac aggctcgaaa agccctatta aaccgacagc aacaatcctc
    19261 acacagtata gttgacttaa ctacctgatg tcatttctgg ctgtttttat aatgacaatg
    19321 gcaatatcgg ttattttgac tatgctgggt gcttgtatcc tagtggactg actgacaatc
    19381 agggcttctt tttcaaccac gaaaacatta aaaaagtctg gtttggaggc tatattgacg
    19441 atagtgaaag agaagctcaa gactttttta aaaaagaggc aggctatatt aaatatccta
    19501 aacttagtat agataatagc actagatagc attaatttaa gtatataacg ttatgattat
    19561 ggttggatta gttcattata cactagcaat aaggtagatt attttgttat aataaaatat
    19621 atacaattat tagagagtta gaaagagtta tatggtagta ttacaaaata atagtagcac
    19681 agctagtgag cgagcgacag ctttggcaag aggagtccag gccctctcta gtgctggtgc
    19741 ggtgagcaaa gatatgaaga cgaccgttac tggaaatcgt agtgatgcca gctctgccat
    19801 tgatttatcg cacaacgttt cagcgcaggt agttgggatc atcgcttcta tgtcgcaaca
    19861 cattcagagt gtctctgcct cttttcaagc gatggatctt cagcttggaa aagagttagg
    19921 gcgtttagaa aacaggcgga ggtttagtct caatgaccca aaatgagctc atgtaccaga
    19981 aggagagatt ggataaacgc ttggaaacca tagcccaaga gcttaagcgt aatgaacagc
    20041 gctttgaaga ctatgaggaa ctatctaacc tagcggcaca actgttaaca gcagctgcaa
    20101 ccacctttcg ttcatcatca gatagtcatc tctttgaagg ggctttggca gaagaatgtt
    20161 atttgaaaag gaaaacacaa gcgtccttgg aacaaagtca tgaggagctc ttaggagagc
    20221 agcgtcgttt gtaccaagaa gaggaagccc tcacccgaca attaaagcta gtcaaaggaa
    20281 aggagagagc taatgagcat tgacatgtat ctggggtcat cggaccagca agctagtagc
    20341 gttggtaagg tcttgcagca gcggataaca gcttataagt ctttgcaaag agctttggag
    20401 caattggtgt cttctagtcc tgacttatca gggcatacct atgcttctgc taaaaggtac
    20461 agcgagcagg tattgatccc tttgatgagg ggctgtatcc tgctagatga agccatcaag
    20521 gaagcctgtg cagcatttcc taatgactac cgtcgtcagg ttgatagtgt ggatttgaag
    20581 gagagtgagc tggtggatca gatcagccgc tcagaccgca tcataggtcg ttacgttgag
    20641 ttgattgatc tggagtatcg gcaggagctg ccgaattact cttatattac taatctcaag
    20701 agcggagcga gtaaccagcg tcaagtcaag agaaaattag aagagaagct ccttaagctg
    20761 cgagagtttg atagcaattc ccgtcacctc ttttcgtcta tcgcagcctt agccgaggca
    20821 gtcaatatag gtatcagaca aaccaagacc tcttggaatg ggacaagtca gacgttcact
    20881 cttcccaggg ctcttgactt agagtggacc aaggtagtag aaaagaggtg gacgcaaagg
    20941 gaggaaaaag cctcgaagct gaagctacag caggcagcag aaaaactttc gagagaaacc
    21001 gggattaagt acgaagatgc ctatcgtttt gtgatggacg gtgttctgtc agatgaaaat
    21061 aagaacaaaa tcaagagtgt aaagaaacta gttaagtata caaagggtgg gctgtatatc
    21121 gtttcctcag gaaggtatta ttggaaacat tcaggtaaac attattggaa aaatacacca
    21181 aacaaaacat ggaatatttg gaaagcatct aaaaacgatc ccaattttga caaaggaggg
    21241 atcaaaggta aacatttttc taaaaaagga gcccgttaca cagacttacc tggtatcaag
    21301 caattgaaga agagtgaaac agtacaatcc ctcatttcaa aaatttcaaa agataatcaa
    21361 gggaagctca ccaaagttgg taaagggtta aagaaagttg ataaagagct aagcaacata
    21421 tcgtcaaaac tcaagtcata tgagcatgga cgcctaaata gagacttgaa aatgatgaag
    21481 gagaataacc tgggtaaaag tctcggtaag tttgggaaag ttggaaaagc tgcaagcaag
    21541 gtgctcaagt ttgcaggaaa aggtctcaaa gttgcgggtt gggtaggtgc tgctataaat
    21601 gttaaggact cggttgaaac ttacaagaaa aaaggctata gcaatgagca aactgctgct
    21661 ttaacagccc gtaaggtagc tgttgatact gcaacaactg ttgtcggaag caatattggg
    21721 cgtgtaacag gtgcagttat tggtcaagca gttataccta ttccaggtgt aggtgctgct
    21781 atcggttctg ttgcaggaag tattttagga gctatggcag gtagttggat tggtagtaca
    21841 attaatgaca atttagataa gaacgtaaaa cctaaacaat caggaaggag tttagcatgg
    21901 taatgttaat gagaacactg ttatttccag ttgataacgg acttgattca ggattgactg
    21961 gtgatggtta tgcagctgag tatgatttgt ggactggaaa ggtcacgtgg cgacaacttg
    22021 gtgatggaaa aataaaaagg caacaaaagg tagcagctat aattaatctc attgcagctg
    22081 caatatctcc acttgtcatc atgtctatca tttttacggc aaaaagtctg aagctttttg
    22141 atgtagatac tagtacaaca atttatcgat atgctcctct gatggtaggc ttggtctttt
    22201 tcttctcgtt tgaattattg atgctggcta ttagacgtct gtatccatta gccaaagagg
    22261 agccaagttt aaagcgtcaa catgggtatt ttaagaccat gtatgacaat actatacgtg
    22321 agaatgatgg tgtttttaat aatttatcag taccttttat agggctttat gtagctttct
    22381 tgattgcctt ttcggttatt ccaatttttt actctcaata tctgcagcaa aattcttttt
    22441 ggtcctattt aggaaattta gtaggaagta gcattcttat ttccttagtc cccaattttt
    22501 tatggaatgt cttagtgaaa caattgattt acatcaagct tattcgcaaa acgaaagaaa
    22561 aaatcttaaa gaatgaaacc taaacaatca ggaaggagtt tagcatggta atgttaatga
    22621 gaaccttgtt atttcccata gataatggta tggataataa cttaattgga gacggcttat
    22681 cagctgagta tgacctatgg actggaaaag ttacgtggcg tcagcccagt gatgataaga
    22741 ttagaaccca acaaaaggta gcatttgtac ttaatcttat agctggtagt ttatctccat
    22801 tagctatatt tttatttgtt attattgtta gacgcttagg cgtttttagt ggcgatacta
    22861 attcaatgat tttcaagtgg gcaccgctaa tagttggatt tatccttttt atatcgtttg
    22921 aattattgat gttggcgctt agaagtagat atacgatatt agagaaagag cccgatttag
    22981 atcgtcaact atactattat cgtacaatgt atgataatac tatacatgac aattcaggtg
    23041 tttttaacaa tttatcagta ccttatgtag gtctatacat tactttattt ctaatttttt
    23101 taatcattcc actttgttat catttttact tgcacccatc ttcatttggg gattatctcg
    23161 ctgcattatc tgtaacaagt ttgttgattt ccttatttcc caatttttta tggaatggtg
    23221 tcttgaagca cgttatatat gtcaaactta ttcgccaaac aaaagaaaga attttaaaga
    23281 atgaaaccta aacaatcagg aaggagctta gcatggtaat gttaatgaga acgctgttat
    23341 tcccagttga taatggcatg ggaacgggct tgaccggtga tggttatgcg gctgagtatg
    23401 atctatggac tggaaaggtc acgtggcgac aagccaccaa acaaacaatt gaaaagcaac
    23461 aagcactaac gtctaacctt ttgattattg cctcatgctt atcaccagtt actgttgcag
    23521 gaatgatact gttgagtaga agtttcccta ttttcgagga agacttatca gagaaaattg
    23581 atacttatgc tccaattatt cttggtgttg tgttatttct tgcttttgag acgttaatgc
    23641 ttgctatcag aggtcgtgat ccattagcgg agaaggaacc agatttaaag cggcagcatg
    23701 actattttga aaagatgttt gattttgcta ttcgtagaaa tttgtcgtca gataatctaa
    23761 aaactcctta tatagctact tattttgctt ttggtatttc tttactctgt attccattta
    23821 gctattatgt ttatctgaat ccggagcaat tccctaattt ggattatggt catttatcaa
    23881 tcctgcttgt aacaagtatt cttatttccc tagttcccaa ctttttatgg aatgttctat
    23941 taaagcacat tatctatatc aagcttattc gcaaaacgaa aggacaataa aacattatga
    24001 acaaaccaga acacatttta ccgattggta ctatagtgct gacggagaca ggagaaattc
    24061 ctttgatgat tgtgagtcgt gcctctcttt ttgatgataa tggagaaatc ggctattttg
    24121 attatgctgc agttccttat ccagaaggca taggaaatga taatgagtac cttttcttca
    24181 accatgagga tattgctgat gtcatctatt ttgggtatgt caattccaat gaacagcttt
    24241 ttgcagaagc ctacgatgat ttggtgaaaa catcaggtta tcgtaaatta agcttagatc
    24301 accatcaata gaaaaaggac atgaagatta tctagaaaaa gaaaagaact aatgagcatt
    24361 gacatgtatc tggggtcatc gaaccagcag gctaatgatg tatggccaat attttgagag
    24421 gatcggcctg ctcctctttt ttgtatgttc aaagctataa aaagcttact ttttgaggta
    24481 taaagcttcg acaatcaaga gtatttgctc tggtggcttt aatgatcttg cttatagctt
    24541 ctggtcagat tgttttagcc tgcttgtgct gtctgatcca gatttgactg aggctttgat
    24601 gacagtcgtg aaggcgggtt taagaatggc atgtctaatg tcaatttaca atagagaagg
    24661 aaaattgatc aaacagtgtg agatattatt aacaagtttg cgctttcatg gtataataaa
    24721 gtgctaggaa gcattttatt ataagataag ggggaatcat ggaagcactg aaaaagattg
    24781 ccggtgtgac tgctgcgcaa tatgtaacag atggaatgac cattggatta ggaacaggat
    24841 caacagctta ttactttgtt gaagaaattg gtcgtcgcat caaggaagag ggactacagg
    24901 ttgttggtgt gacaacctca agtgtaacaa ccaagcaagc agagggccta ggtattccct
    24961 taacatcaat tgatgatatt gactgcattg acctgactgt tgatggtgct gatgaggtgg
    25021 ataaggcctt taacggtatt aagggtggtg gagcagctct attgatggag aaaattgttg
    25081 caacaccaac caaggaatac atctgggttg ttgatgaatc aaagctggtg gatcatttag
    25141 gtgctttcaa gctccctgtt gaggtcgttc aatacggtgc tgataggcta tttcgagtct
    25201 ttgaaagggc tggctataag ccctcttttc gcatgaaggg ggataagcgt ctcataacgg
    25261 atatgcagaa ctttatcatt gatcttaacc ttggctgtat cgaaaatcct tgtgagtttg
    25321 ggcgtctgct ggatcaaact gttggtgttg tcgagcatgg ccttttcaat ggtatggttg
    25381 ataaggtcat tgttgctggt caggctggtg taacggtcct tgaagctaat cagtcaacct
    25441 aattcctagc tcaatcatgt tttacattat tttataggtt ttggggagcc aaccgtaacc
    25501 tcccctagat tggagactta tgtcaaaatt taatcgtatt cacttagtcg ttctagattc
    25561 tgttggtatt ggtgcagcac cagatgccga caaattcttt aatgctggtg tagctgatac
    25621 agattctgac accctcggtc atatttcaga gacagctggt ctggctgttc caaatatggc
    25681 aaaaattgga cttggtcata ttcctcgtcc tgtcccccta aagacagttc cagctgaggc
    25741 tgatcctact ggctatgtca ccaaattaga agaggtatct cttggtaagg ataccatgac
    25801 aggtcactgg gaaattatgg gcttaaacat tactgagcca tttgatacct tctgggatgg
    25861 ctttccagag gagattatcc aaaaaatcga agctttttca ggccgtaagg tcattcgtga
    25921 agccaataag ccttactcag ggacaaaggt gattgatgat tttggtcccc gtcaaatgga
    25981 aactggtgag ctgattgttt atacctctgc cgaccctgta ttgcaaattg cagcacatga
    26041 ggaggtgatt cctgttgagg agctttaccg gatttgtgag tatgcgcgtt ccattaccct
    26101 tgagcgtcct gctcttttag gtcgtattat tgcccgtccg tatataggag agccaggcag
    26161 cttcactcgc acagctaatc gtcgtgatta tgcagtctca ccgttccaag acactgtctt
    26221 aaataagctg gctgacgctg ggatttctac ttatgctgtt gggaaaatca atgacatctt
    26281 taatggctca gggattacca acgatatggg gcacaataag tctaacagtc atgggattga
    26341 taccctgatc aaaagcttgc agttgccagc atttacaaaa ggtctttctt ttactaactt
    26401 ggttgatttt gatgctagct ttggtcaccg tcgtgatcca gagggctatc gtgactgttt
    26461 gcatgaattt gatcgtcgcc tgccagagat cattgccaac atgaaggacg atgatctgct
    26521 cttgattaca gctgatcatg gcaatgaccc aacctatgct ggaactgacc acacacgtga
    26581 gtatattcca ttgcttgctt actcagcctc ctgcactgga gcaggtgtga ttccacaggg
    26641 acattttgct gatatttcag cgactattgc cgaaaacttc ggtgtggaca ctgctatgat
    26701 tggaacatca ttcttagctg acttggtata ggagtaagca aatatcattt gataggccaa
    26761 ggagcttggc gtatcaaatt gaaaaccagc gctgtggtta ggtctattaa taggcttgtg
    26821 gcaggttgtc tagttctgat gatcggtgtg atattagttg atttattgga ctttgctaca
    26881 gcaaaaagct caagagaagt atgctttata gtaaaaaata aataagataa agggagaaat
    26941 aagatgacat tacttgaaaa aattcgtgaa acacaggctt tcctagaaag caagggcatt
    27001 gataagcctg aatttggtct cattttaggc tctggtctag gtgagcttgc caatgaggtt
    27061 gagcaggcga ttgtgattga ttatgctgat attccaaact ggggcaaatc aacagttgtt
    27121 ggtcatgctg gaaaattagt ttatggtgag ctggctggtc gtaaagtatt ggcacttcaa
    27181 gggcgctttc atttctatga aggtaatcca atggaggttg tgaccttccc ggtacgtgtg
    27241 atgaaggctc tgggctgcca tagcttgctg gtgacaaatg cagcaggcgg tatcggctat
    27301 ggtcctggga cgcttatgct aatcaatgac catattaata tgacaggaac aaacccgctc
    27361 attggtgaaa acctagatga atttggccca cgcttcccag atatgtctga tgcctataca
    27421 gcagcttatc gtgagacagc tcgctcagta gcagaaaaac taggcttaga cctgcaagag
    27481 ggtgtttacc ttggctgttc aggaccaacc tatgaaacac cagctgagat tcgtgccttt
    27541 aaggttatgg gagcagatgc tgttggtatg tcaactgttc cagaggttat tatcgctgcc
    27601 cactcaggct tgaaggtgct tggaatttca gcgattacaa actttgcagc gggcttccaa
    27661 tcagagctta accatgaaga ggttgtagag gtaactgagc gtatcaagga aaactttaaa
    27721 ggcttggtta aggctatttt ggcagagctt taaggcttgc tcttagacta gcagtaacca
    27781 tgagcgactg ctagtacttt gatcgataag acgaggaaaa ataaggattg ggacattaga
    27841 gtgatgactg atatggaaca tacgataagt attcttttag aagtttatgc ttatagtcat
    27901 gcctacaaaa ttgcaagaac tctgcctgat ttttccccca aggtacttta tttgcttgag
    27961 cttttaaagg aaagaagaga gcttaacgtt gcttatgcct ttcaacatag ggcggaaaat
    28021 aggcttattg aggatagaca tcaggttaag cttttgttaa atgaagctca agaggaggag
    28081 cagactgcaa attacctgct tgatttggca gctaaggtca aaaacggtga gattattgat
    28141 tttgtaaggt cagtatcgcc tgtcttgtat cgtctctttt tgcggctgct tgagcaggct
    28201 gtcccagatg ttcaaagcta tattattgat accaagaatg atcaatatga cacttggaat
    28261 tttaaggcga tggaaaaagc cgataatgac ctctttagga gctatctggc acaaagacag
    28321 ccacgtcatg tgacgacacg cagcttggct gatttacttg ttttatcaga gcttccagct
    28381 gatattaaaa gactagtggt agtcttaagg cagtttgaaa aatcagtccg caatccccta
    28441 gcacatttga tcaaaccctt tgatgaggag gagctatatc ggacaactca tttttcctct
    28501 caagcctttc tagatggttt gattcgctta gcagtttttt ctggtgttaa ctatatcaaa
    28561 gagcccttct attttgatgt cgttaatgct gtcattgaaa aggagctgtt agacagcgcc
    28621 aagccttagc tatttgaaag attagcaata ataaaaaacc tgaacgatct gaacgaggct
    28681 tctctaagct agctatgact agtcagctta gagccttaga acaggtcttt caggtttttt
    28741 atgtttagct agtgtggtta attaatgatt gaagctaatt tcttctagca ggtagtcaat
    28801 aaatcgctct cccatttttg agaggttagc cttttcgtgc ttgataaaga caatctcaat
    28861 cacatcaggg acatctaagg gaatagcgac aatctggtct ccatttagat ttgtgtttaa
    28921 aataccgctg gcaacggtgt agccatttaa gccaatcatg agattaaata gggtagctcg
    28981 gtcactcacc acaatagact tactgtgagg gatatgtgcc atcatctcct ctgagaaata
    29041 aaaggaattg tgaatcccct gatcatagct tagataagga aaatcaagga gatcatcaat
    29101 ggttaagctg gttttatttg ccagaggatt ggacttgctg ataaagatat gcggtgtggt
    29161 tttaaatagg gtggaaacgg tcaaatgatt ttcctcaaac agcttggtaa ggacgtctcg
    29221 gttgtagtca ttgataaaca aaacgccgat ttctgagcga aaatttttca catcgtcaat
    29281 gatttcccag gttcttgttt ctcgcaagaa aagctcgtac tgggtcatat cagcccgctt
    29341 taataaagag acaaaagcat tgacaacaaa ggcgtaatgc tgagaggaaa cactaaagag
    29401 ctcacgacta gtattgtgat ttttatagcg atcctctagc agtgctgttt gttcaataat
    29461 ttgtctggca taagatagaa actcaacccc gtccttggtt aaggtaatgc ccttgggatt
    29521 acgaatgaaa atagtaatgc ccatctcctg ctctaattcc ttgacagcat tagacagact
    29581 gggctgcgtg ataaataatt gcttagcggc ttcgttcatg gaaccgcatt caacaatctt
    29641 tataatgtat tgtagttgtt ggattctcat actgacagtc tatcttaaat agtacaaaga
    29701 atcaagtgcc tttattagag cttaagacaa ggtttcacaa gcggtagcct agcttgtgcg
    29761 gtgaagctag cttgatgcta gtgttgtacc caggtaaaaa agagctggca aataggcagt
    29821 tttatcgctt tttaccgctt atttttggca tgcctgtgtt ttgataaacg gctggtcttg
    29881 atcggtaaaa agtaatcgtg ataatgtcag ataataccta tttttccatt gctcttttaa
    29941 ttttcttgtg ttatattaat aatattgata tatttaatgt tttgagataa agggtggtga
    30001 tggtgtaata tgactggaca aagtagtcat caggtattaa ttcaaaagct gttggtcagc
    30061 actcactatt tgacattatt tagagatgag ctgaagctag ttgagaggac accatctatt
    30121 ttgggaagtg agtttcctgt ctctcttgtt caaacggaat taggtgatat tatcaccttg
    30181 gtggatacct taaataagca gcagcgcttg attgagtcga ccttttggta tgaggagtca
    30241 gcctttaagc tcatgaacaa ggccttagat attgttgata attggataaa ggggatagat
    30301 ggcttaatta agctctgcca gtccaaggag gtctttcagg ccattgttgg tgataaaaga
    30361 acacgtgttt ttggtgtttt gattgatgtt ttttcttccc taaaaattag caccatgtca
    30421 ttgaaggaat ttgcagctcc ggctgctctt tgccattaga ttaagctggg ctaagcttgg
    30481 atagtggctg gttaagcctg caagttgccc ctctcatgac aagtctaggc tttatttagg
    30541 gtgagcagtg tgccaagggt gtattaagtg ctggttgctt tgaagcttcg ccttgctagg
    30601 ttagctgtga gtgatgtcac gataactgcg cgaaacagtt atttctgaat tataatacag
    30661 gttaaagtag gtacttttaa tgtttttcct attgtaaaat ctatacaaaa taggatatat
    30721 ttttgaaata gctgaacatt aacgtacagc aagctttatt ttcttgctaa aaatcttttt
    30781 tatacctttg tcgtgtgagt aatgtcaaaa ccctttgaca agggctgtca aaaaagctat
    30841 aatgattgag ataagttacc tttaagtgag tccagagagg cgagcaaggt acacaggata
    30901 agatgagagg gtttgctctc ttgattttcg tgtagcctcg cttctttgga agtgaggctt
    30961 ttatggtgtg actttcagtt ggtctcgtgg taatgattca taagaccaat aaaccgctcg
    31021 ttagacgggt gggcatgatt tgtttgggag taccccaagc tgcatagaaa ggataggtta
    31081 tgcgagaaga acgccctatt attgccttag attttccttc ctttgaggag gtcaagtcat
    31141 ttctgtcgct gtttccagct gatgagaggc tatacgttaa gattggtatg gaactgtatt
    31201 atgctgaagg accagatatt gtccgttatg tcaagtcctt aggtcacagt gtttttctgg
    31261 atttgaagct gcatgatatt ccaaatacag tcaaatcaac gatggcagtc ctatcaaggc
    31321 ttggtataga catgacgact gtgcaggctg ctggaggtgt agagatgctt agagcagcgc
    31381 gtgagggctt ggggcagggt ccgattctca ttgcggtgac acagctaaca tcaactagcg
    31441 aagagcaaat gcgtgaggat caaaacattc aatccacgct gttagcatct gtgcttcact
    31501 atgccaagcg taccgctcag gctaagctag atggcgtggt ttgctcagcc catgaggtca
    31561 aggccattaa gtcagaagta ccagcaggct ttgtgtgttt gacacctggg attcgcccga
    31621 caggtgctga catcggagat caaaagcggg tgatgacacc tcatcaagct agagctatcg
    31681 gaagtgacta tattgttctt ggtcgtccga tcactcaggc tacagaccct gtcaaggctt
    31741 atcaccagat taaggcagag tggaaccgtt agcagcagga tcatcatgac acatatagct
    31801 ggactatgac accaaggaaa agaggagaaa aatgacacta gcagcacaaa ttgcaacaga
    31861 tttacttgag attaaggccg tttacctaag accaaaggag ccctttactt gggcgtcagg
    31921 cattacatca ccgatttata cggacaatcg gatcaccctt tcttatccaa aaaccagaag
    31981 cttgattgaa aatggctttg tggagacgat taaggcagta tttccagagg ttgaggtgat
    32041 tgctggcaca gcaactgctg gtattccaca tggtgctatc gttgcagata agatggacct
    32101 gccttttgcc tatatccgca gcaagccaaa ggatcatgga gcaggcaacc aaatagaagg
    32161 gcatgtgcgc tgcgggcaaa aaatggtgat tatcgaggat ttgatttcaa caggtggatc
    32221 agttctggag gcggcagcgg cagctagtcg cgaaggtgct gatgtactag gagtggtggc
    32281 aatttttacc tatgaattgc cagtagcaag catcaatttt gaaaaggcag ggctttcctt
    32341 ggtgaccttg tctaattatt cagacctcat taaggtcgct aaggccaagg gctatattga
    32401 tgctgatggc ttggccctgt taaaaagatt taaggaggat caaaagcatt ggcagcatga
    32461 gagttaaaca gtgctgaaaa gctgctgaca tgctgactat gtcttaagga gagaaaaaat
    32521 gacttacaaa gatttacttg agataggtga gaccagttat tatcagacgg atcgcttgac
    32581 ttactacaaa aatcctgtgg tatctgagcg ctattttgat aattacctta gctatcgtag
    32641 catgccttct ttggctgatt tgaaaaagga cttggcctat gtggcaaaag agcagcagga
    32701 ttatcctagt cactacgcct ttctcttttt tgctgaaaat gaagagctaa gtacagacat
    32761 gcgagcttat ttgacagatc atcactttag ccttgaaaag cacctgatct ttaccaatga
    32821 gctggcaaag cttcacctaa aggagcgtga tatatcacca gtcactattg aacagctctc
    32881 agaaacaagc ttttctgcct atctggctta caaatatcag gctaatttgg cttatggtga
    32941 aacctatgcc aatcaatgca aggctgataa tgaagccaat ctattgacaa acggctcaac
    33001 catttattta gccatcaagg aagggaagat tatcggagat attacggctt gggaatgtgg
    33061 cgactatatt gaaatggacg atttcagtgt agatgaggcc tatcgtggtc gtggtatcgg
    33121 tacagcctta cagcgtaagg ccagtcaagg ctataagaag gtcattctca tctcagaaga
    33181 agctaatcgc gccatgtatg agcaccaagg ctatcaggag gttgcttact actggacagc
    33241 gctaaaaaca tcgactagat aagtgataaa gaaacagatt ataggattga aggtgtaggc
    33301 tcttatgagt atgactcttc aatccttttt ttctgagcgc atttgctaat catacctaat
    33361 gaataagtcg tagcctgtct agtggctcat tttaatggcg tcttgctctg ttttatgatt
    33421 aaatatagag aaaaagctat tgttagggca tgcttgttgg tctagcaagg ctgatggatg
    33481 ataggatagg gaattgatga tttttaaaga tgcaacagaa atggcgcagg ctgttcgaga
    33541 aggtagggtg agcccctcag ccttagtgag agacacaatt aaaaaggctc aagcactcaa
    33601 tcctgagttg aatgctatta cctcagagcg tttttcagaa gctcttgctg aggcagcagc
    33661 aagggatttt tctggaaagc catttgctgg tgtgcctatt tttctaaagg atttagggca
    33721 ggagcaggag ggccaattgg ccactgcagg atcagtgtta tttaaggatt atcgtgcctc
    33781 aaaaacggat tatgttgtgc agcgactaga ggagctgggc tttattattt taggaagaag
    33841 caatacacct gaatttggct ttaaaaatat tagtgatagt cgcttacatg gtccggtaaa
    33901 tctgccacag gacaagagcc gtaatgctgg tggttcatca ggtggggcag cagctcttgt
    33961 gtcctcagga atcaccttgc tggctcctgc tagtgacgga ggaggatcca ttcggattcc
    34021 tgcctccttt aatggcttga tcggtttaaa gccaagcaga ggaagagtgc ctgtggggcc
    34081 aggctcttat cgtggctggc agggggcgtc tgttcatttt gctctaacga ggtctattcg
    34141 agacacaagt cgtcttcttt atcacttgca ggtttatcag gtagaaagcc cttttccatt
    34201 agtgccatta accaaagaag agctttttca ccctttagac agacccttaa ggattgctct
    34261 ttatgatcac atgatagatg gaactaccgc ctctatagat gctcagacag ctttaaccga
    34321 ggcctgtcat tttctaaaag agatggggca tgaggttgtg cgattagata agcttcctct
    34381 agatatacca aaggttatga gggattacta cctgatgact agtgttgaga cagctgctat
    34441 gtttgctgat agccaagaag cccttggtcg tcaggtgacc aaagcagata tggaggtcat
    34501 gacctgggct atctaccaag cgggtaagga tattcttgct tcggtctatt ctcaggcgct
    34561 gcagcgctgg gaccattata gtgctgaaat ggcaagcttt catgagcagt atgatctttt
    34621 gctgaccttt accgccaata cgcctgctcc aaagcatgga cagttccagc caagcaagga
    34681 gctaatagat aagctggcta aggcggaatg ctacccctcc agtcagcgcc tagcgctagt
    34741 agaagccatg tttgagcaga gcttgttcat aaccccttac acagctttgg caaatctgac
    34801 aggccaacca gctcttagtt taccaaccta tgaaacgtct gctggattgc cgatgggcat
    34861 tcaattgata gctgctaaag ggcgagaaga cttattgctg ggaatagcta gacagtttga
    34921 acgggctgga ttgttaaagc tacctggtta aatattataa aacagagcta atctattata
    34981 ggttagcttt tttgttaaat cgagcatatc tagtctctta taagattagt caatgctata
    35041 ctgtcattaa taatgaaaaa ggagttcttg atgaaaaaag gagttgcttt actttctgtt
    35101 agcttggcga gcttgctgtt agccgcctgt gggtcacagc catcagctca aaaaacaagc
    35161 tgggaaaaga ttaaagataa aggtgtttta aaggttgcta cgcctgcgac ctaccagcca
    35221 acatcgtact ataatgatgc caatgaattg gtcggctatg aggttgacct gatgaaggaa
    35281 attgggaaac gccttgatct taaggtgaag ttcattgaaa caggctatga tcaggctttt
    35341 acttcggttg atagcggtcg tgttgatgtt tctctcaata attttgacat tacagccaag
    35401 cggcaaaaaa aatacaacat ctcaacgcct tataagtatg gtgttggggg aatgattgtt
    35461 cgtgctgatg gcagctcagg cataagcaag gctgacctaa gcgattggaa agggaaaaaa
    35521 gcagctggcg cctctggtac agaatacatg aaggttgcca agaagcaagg tgctgaatta
    35581 gtcacttatg ataatgtgac gggtgatgtt tacctgaacg atgttgctaa tggcagaaca
    35641 gactttattc ccaatgatta tcctgcacaa aagctttttg tggattacat gaagtctcaa
    35701 aatcctaacc tcaatgtcaa aatgagtgat gtgctgtata atccgacagc acagggcatt
    35761 atcatgagta aaaaagatga cacccttaag aaaaagattg atgcggtcat caaagacatg
    35821 aaacaagatg gcagcttgaa aaccatttca aagacatact atgctggtca ggatttgaca
    35881 gttccttttg gtaaggacaa gaaaattcca gtcattgatg ccagtgatgt ggactagtgc
    35941 cttagacaaa ggagctctaa agcgatgctt aatcttagat tgatactaga gagcttgggc
    36001 tttgttttgt caggtttgcc ctatacctta ggcatttctt ttttaagctt tctaacaggc
    36061 cttttgctgg gcttgctttt agccttttta aggcgttcta ctagtcactt tagtcattat
    36121 ctggtcagga gctatgtgtc cataatgcgt ggcgttccta tgattgtggt gctctttgtc
    36181 ctttattttg ggcttcccta ttatggctta gaactgtctg ccttgttatg tgcctatttg
    36241 ggcttttcac tggttagtgc agcctatatc tctgaggtct ttcgtgcctc gattgatgct
    36301 attgatcagg gacaatggga ggcagcaagg gctttggggc tgccttatgt cagcattgtc
    36361 aagcatgtga ttctgcctca ggcctttcgt attgctattc cgcctttagg aaatgttgtg
    36421 attgatatgg tcaaaagttc gtctttggca gctatgatta ccgttcctga tatttttcaa
    36481 aaggctaaaa ttattggtgg cagggagtgg gattacatgt ctatgtatat cttggttgcc
    36541 tttatttatt gggtgattgc ctttttgctg gagcgctgtc agggcttttt agaaaagagg
    36601 ctgcgcttac tctcttaaaa accgaatatt taccctagaa atattgtatt tctagggttt
    36661 ttatgataaa aatatgatag actaaagtag cctaatcagt tagttagctt tgtcaagaac
    36721 tgactggcta gagtgttgga ggtaggatat ggcagactct attgtatttc ggaaaaatca
    36781 tatgatttca actcaggcct ttgctcgagt gctggaagcc tcagggatta aaagaccgac
    36841 taaggacgag gctagattat cgcaaatgct aaagcattcc aattatctat ggacagcatg
    36901 ggaaggtgac aagttagttg gtgttgctag agcccttact gactatgctt atgtctgcta
    36961 tatttctgac ctagcagttg atcaggcata tcagggtcaa gggataggca agcaattgct
    37021 gtcttttatc tcagaggatc ttggagatgc tgttgctctt gtattgctgt cagcaccttc
    37081 ggcgatgtcc tattacccta agcttggctt tgaacaatca gacaaagcct tcattattcc
    37141 acgaaaaccg ttttagagag gtatctaatg acacattcag cttggcatga tgagattaag
    37201 caagtgttac ctaaggatta ttatcggcgt atcaatcgct ttttagatga ggtctatgcg
    37261 actggagtgg tttacccgcc cagagacaat gtgtttaagg ccttacaggt aacgccatta
    37321 gaagagacaa gagtgcttat tttagggcag gacccttatc atggccctct tcaagctcag
    37381 ggactttcct tttcagtgcc tgactccatt cctgctccgc catctttgca aaatattttg
    37441 gaggaattag cagcagatat tggagtaagg aatcatcacg atcttagcag ctgggctgag
    37501 cagggagtgt tgctcttgaa tgcctgcttg accgttccag aaggacgcgc caatgggcat
    37561 gcaggtctca tctgggagcc ctttaccgat gcggttataa aggtcttgaa tgctaaggat
    37621 aggcctgttg tgtttatcct ctggggagcc tatgcgagaa gaaagaaggc cttgattact
    37681 aatccgattc accatgttat cgaaagccct caccctagcc ctctgtcagc ctatcgtggc
    37741 ttttttggca gcaagccctt ttcaagagct aacgccattt tagaaaaaga aggcctagga
    37801 cagattgact ggctgcgcta ggcattgagg caggctatta tggctaagca ggacgattta
    37861 ccaataaagt atccggcttt ggagacttgg gtatacctag ctaaatagag attgatgata
    37921 tcagggatca agacagttac gtccgatatg tcaagcaaaa caaataatca ctgcctagat
    37981 aaatcagaaa ttgctagggt tatgcttgat tatcctgata agcagataag tagatttgac
    38041 ataggagggg tcatgttatt aattaaaaat gggcgtgtga tggatccaaa atcacagcta
    38101 gatcaggtgg cagatgtctt aattgataat ggaaggattt tacggattgc tccagacatt
    38161 gagcatgatg aggtagagca gatcgatgcc agtggacttg ttgttgctcc tggtttagtg
    38221 gatattcatg ttcattttag agagccgggt caaacgcaca aggaggacat tcatacaggt
    38281 gctctggcag cagctgctgg tggggtgaca acagtagtca tgatggcaaa caccaatcct
    38341 gttatatcag atacggaaac cttacaggct gttctagcaa gtgctgctaa agaaaaaatt
    38401 aacatttata ccaatgctag tgtgaccaag cggttcaatg gccaagagct aacagacttt
    38461 aaagcgctct tagcagctgg tgcggtcagt ttttctgatg atggcattcc tttagagagc
    38521 tccaaggtct taaaggaagc attggatttg gctaaggcca acaagacctt cattgccctg
    38581 catgaggagg atccccaatt aaacggtgtc cttggcttca atgagcatat cgctaaggat
    38641 cattttcatt tttgtggcgc tactggtgtg gcagaatata gtatgattgc cagagatgtg
    38701 atgattgcct atgatcgaca agctcatgtt catattcaac atttatctaa ggctgagtct
    38761 gttaaggtag ttgcctttgc tcagcagtta ggtgccaagg tcacagccga ggcaacaccg
    38821 cagcattttt ctaaaacaga agacctttta cggcttgcag gggcaaatgc caagatgaat
    38881 ccgcctctaa gaacagaaca agatagatta gcagttattg aggggctcaa atcaggtgtc
    38941 atagctatta ttgcaacgga tcatgcacca catcatcgtg atgaaaaggc cgttgctgat
    39001 ctgaccaagg caccatctgg aatgaccggc ttagaaacct cattgtcatt aggcctgaca
    39061 aatcttgtgg agccgagcca tctttcattg atggcgttat tagagaaaat gaccattaat
    39121 ccagcctcac tatatagctt tgatgctggt tatttggctg agtctggccc tgctgatctt
    39181 gttatttttg ctgacaagga ggagcgtttg gtaacagaag cctttgcttc aaaggctagt
    39241 aattcacctt ttattggcga aaccctaaag ggagttgtga aatacaccat tgctaaggga
    39301 caaattgttt atcaggcaga caactaatca acacttaaaa agctgagcat ctgatagtaa
    39361 ctgatgctca gctttttgat ttagtgatgg cttgcgggct gctgcttgct taagttcaag
    39421 ccccaaggaa tgagattttc agattgctgc ttgattcgct tcatattatc ctgatgcctt
    39481 aggataatga ttgctgctag cacaacgatg gtaatggtta atagccaatc gtagctaggc
    39541 aataaaaagt gggcggcagg aaaagtcaga acgctaatca cagctactac agacgctgtt
    39601 agactagcta gtgaaatcat gctaaataaa taaagcgtta gcacaaacac agccgctaaa
    39661 aaaaggagat agagtggggc aaagcctagc aagacaccag cactggttgc gactgccttt
    39721 cctcccttga agccagcgaa aataggaaag gtatgcccta ggacagcaaa aaagccaata
    39781 gtaattggtg agatattgct agcgccaacc aaaaccggaa gaagcgtggc aagcgtgccc
    39841 ttaaaaatat caatcaataa ggttgcagca ccagctttta gcccaagaat ccgaaacgta
    39901 ttggtcgtac cggtattacc tgagccatgc tcacgcaggt tgatgttata gaaatactgt
    39961 ccaatccata agcctgttgg aatggagcca agtaaatatg ctgtaagaat taataggatc
    40021 aatttcataa catacattat atcataatga ttgatttaag cggaagcagt tacaaagaat
    40081 tacgaaaaaa tcttaaatta ttttgcaaaa ttctcaaaaa acctgtaaga taaaaaagat
    40141 gaaaacgtct ggaggtcaac ttggctaaga aagaaataag cataacaaat tataatgatg
    40201 atgccattca ggtcctagag ggcttagagg cagttcgtaa aagaccaggg atgtatatcg
    40261 gatcaaccga tgcaaccgga cttcaccatt tgatttggga gattgtcgac aatgctgttg
    40321 acgaggcctt atctggcttt ggaaatgaga tcgatgtgac gctaaacaag gatggttctg
    40381 ccaccatttc tgacagcgga cgaggcatgc cgaccggaca gcacgccctt ggtataccaa
    40441 ctgttcaggt catctttacc atcttgcatg caggtggtaa atttggtcaa ggaggctata
    40501 aaacctcagg aggcctgcat ggtgtgggct cttcagttgt aaatgcccta tcgtcatggc
    40561 tagaggtgga aatcacgaga gacggagcgg tttacaagca gcgctttgaa aatggcggta
    40621 ggccagtgac aggcttagaa aaaatagcta cagctccaaa aagcaaatca gggacaaggg
    40681 ttactttcat gcctgatgac aagatttttt cgacaactga gttcaagtgg aatactatcg
    40741 cagagcgtct aaaggaatct gcttttctgc taaagacggt taaaatgacc ctgactgatc
    40801 tacgaggtga cgatccggtc gttgaggaat ttcattatga aaatggtgtt caggattttg
    40861 ttgcctatct caatgaggac aaggaaacct tgactcctgt gatttacatg gaagggcagg
    40921 agcaggattt tcaggttgag gtcgctttgc aatacaatga tgggttttca gataacattt
    40981 tgtcctttgt taacaatgtt aggacaaagg acggtggcag ccatgaaact ggcttaaaat
    41041 cagctattac aaaggccatg aatgactatg cccgcaaaac cagcctacta aaggaaaagg
    41101 ataaaaactt ggagggctca gattatcgtg agggcttgtc tgcagtgtta tcgatccttg
    41161 taccagagca gcatttgcaa tttgaagggc aaacaaagga caagctagga agcccactgg
    41221 caaggccgat cgttgagagc attgtatcag aaaagctgac cttcttttta cttgaaaatg
    41281 gtgagctggc aggtcatttg attcgtaagg ctatcaaggc aagagacgcg cgtgaggcag
    41341 ccagaagagc gcgtgatgag tctcgaaatg gtaagaaaaa caaaaaggac aaggggcttc
    41401 tttctgggaa attaactcca gcccagtcca aaaatcctaa gaaaaacgag ctgtacctag
    41461 tcgaggggga ctcagctgga ggctcagcta agcagggcag ggatcgtaaa tttcaggcaa
    41521 ttctcccctt acgtggtaag gttttgaaca cagaaaaggc caagatggct gatattctca
    41581 aaaatgagga aatcaataca atggtttata ccattggcgc aggtgttggt gctgatttca
    41641 atcttgatga tattaattac gacaagatta ttatcatgac cgatgctgat acggatgggg
    41701 ctcatattca gaccctgctg ctgacctttt tctaccgtta tatgcggccg ctggttgaag
    41761 caggacatgt ctatattgcc ttgcctcctc tttataaaat gtcaaagggt aaaggcaaat
    41821 cggagaaggt ttcctatgct tggacagatg gtgagctgga ggatcttcgc aaggaatttg
    41881 gtaaaggtgc aagtctccaa cgctataagg gacttgggga gatgaatgcc gatcagctat
    41941 gggaaaccac gatggaccct gacacacgaa cccttatccg agtgacgatt gatgacctgg
    42001 ctagggcaga gcgacgcgtt tcagtcctca tgggagacaa ggctgcccca cgccgtcaat
    42061 ggattgagga caatgtcacc tttaccttgg aggaaaatac ggttttttaa ggcatttttc
    42121 ctaaggaggg ttctaaaata tctcatatca aattgctatt catgtgctca gcattcattt
    42181 atcaaggatt gtaatcattg aggtaacagt gatgaagcta gatatttgtc aacaaagcta
    42241 cagtcttcag tggggaggca cctattattt tgcattgaca gattatccca atatcaaggc
    42301 ttgggaactg gaaaagctag cagccttttg tgcctacgaa aaatggaatc atcgtcaaac
    42361 agacattagc tgtcaggaca gcaagcttct tgaagaggtt catcaatttc ttgaagcaca
    42421 tgcttgtgcc tatctcttta ggcctagctg taaattggtg gcttcaacat ttaacatcaa
    42481 tggagaggca gtctgttgtc cttatttaag tcatacctgc actgtagcgg ctgctctaag
    42541 catttttaag acaggaaggc tattgtctgc tgtaagagct tttggggtaa cggcacagga
    42601 gttggctagg agtgatcgaa atgctgctgg tgatcctgct gattattttc attatgtgat
    42661 gcttggctgg tccaatacga cctcaggcta tcgcttggct atggagagat tgcttaatcg
    42721 tatgccaaat gaaaaggact taagagagca ttttgtaccc ggagttagct ttcactatag
    42781 ctattctgat atttgtcaga tgaaaggcta tgtttttgat ggctatcacc ctgccaagat
    42841 caaagacgag cttagtttgg aggaattgca ggcttgcatt attcctaaaa gctggcagca
    42901 gcgctttgaa gcaattattc caaaggcctt acgctcaagg gttcattacc tagactataa
    42961 aggcgaaggc ttggtcgagt ggtctgatag ggtttatcag ctgttaagag tgatcagtga
    43021 cagctagctg taaataggct agctttatac tattttttga atataataga caatctaaca
    43081 gaaaggaaag ctcagtgaga ggtctcttgc tgggtgtggg atggatttcc tagaaactgc
    43141 taatcctagc gataggggag cgtagcgagc ccattctgaa agctcctgcc gtagtgaaaa
    43201 gaagataatc gcttacgatt atcttcgagg gaaatttcga gccgaagtct cgaaatttag
    43261 gaatggaacc gtaggttcgc ttctgtcccc actacctaaa ggaactttca aaaaaaacta
    43321 attaaagaaa gagatatctt tctgaaagaa acaaagaaag gaatgttcag ctagtttact
    43381 aactgaacac gggactattt ttcctagaaa aatcggtaac ctcctagtgt ccaaggacac
    43441 gtcgtcagtt ccagcatttt ttacggaaaa atttcgcaag cgaaacgtcc ctttgtatct
    43501 tatgagtaat attcaaaaca tgtcccttga ggacatcatg ggagagcgtt ttggacgcta
    43561 ctccaaatac atcattcagg agcgagcgct tcctgatatt cgagatggtc taaagcctgt
    43621 tcagcgccgc attctttatt ctatgaataa ggacggtaat acctttgaaa agggctaccg
    43681 caagtcagcc aagtctgttg gtaatatcat gggcaatttc cacccgcatg gagattcttc
    43741 gatctatgac gctatggtac gcatgagtca ggattggaag aatcgtgaaa ttcttgtgga
    43801 aatgcatggc aataacggct cgatggacgg tgatccaccg gcagctatgc ggtacactga
    43861 ggcaagatta tctgaaattg ctggttacct gctacaggac atcgataaaa aaacagtgcc
    43921 atttgcttgg aattttgacg ataccgaaaa agagccaaca gtattgccag ctgcctttcc
    43981 aaatctattg gtcaatggct catcagggat ctcagcaggc tatgctacag atattccacc
    44041 acataatttg tcagaggtga tcgatgctgt tatttatatg attgaccacc caaatgccaa
    44101 gctggataag ttaatggagc tattgccggg tcctgatttt ccaacaggtg gtattatcca
    44161 aggagcagcc gaaattaaaa aagcctacga aacaggtaag agccgcgttg ttgttcgctc
    44221 cagaactgaa attgaggatc taaagggagg caagcagcag atcattgtga ccgaacttcc
    44281 ttatgaggtc aataaagctg tcctagttaa aaaaattgat gatgttcggg ttaataacaa
    44341 ggttccagac atagcagagg tgcgtgatga gtcagaccgt acagggctac gcattgctat
    44401 tgagctcaaa aaagacgctg acagccaaac catcttgaat tatttgttga agtataccga
    44461 gcttcaagtc aattataatt ttaatatggt tgcgattgat cattttacgc ctcgtcaggt
    44521 tggattgcaa aaaatcttat caagctatat cgctcaccgc aaaagtatta ttatcaagcg
    44581 ctctcagttt gacaaggaaa aggctgaaaa gagattgcat attgttgagg gcttgatacg
    44641 tgtcttatct attttagatg agattatcgc gctgatccga gcttctgaca ataaggctga
    44701 cgccaaggaa aacctaaagg tcagctatga tttttcagag gaacaagcag aggctatcgt
    44761 aaccttacag ctttatcgac tgaccaatac agatattgtt accctccagc aggaagaaca
    44821 tgacctaaga gagctcatca caactctctc tgccattatt ggtgatgaag caaccatgta
    44881 taacgtgatg aagcgtgagc taagagaggt caagaaaaag tttgcagggc cgcgtttatc
    44941 agagctgcag gctgaaagcc aagcgattga aattgattct gctagtctta ttttggagga
    45001 agaaaccttt gtcagtgtga ctcagggagg ctatatcaag cgaacaagcc ctaggtcatt
    45061 tcacgcctca agccttgagg aaattggtaa gcgtgatgat gatcatctga tctttgttaa
    45121 gcaggctaag acaacagacc acctgttact ctttactaat ttaggtaatg ttatttaccg
    45181 tccggtctat gagctgactg acttgcgctg gaaggacatc ggggagcatt tatcacaggc
    45241 tattgctaat tttgctgctg atgagctggt gatatatgct gagttgatcc agtcctttga
    45301 agagggacta tatatctcag tgacacagca tggactgatt aaacggtttg agcgcaagga
    45361 gctgacgcct tggcgaacct acaaatcaaa atcaattaaa tacgccaagc taaaagacat
    45421 agatgatcgc attgtggcaa tagcaccaat tatcatggaa gatcttcttt tggtgacgca
    45481 gcagggctac gccttgcggt tttctagcca agaaataccg attcagggcc taaaggctgc
    45541 cggagttaaa ggaattaacc taaaggctca ggattacttg gtttctgcct gcccagtcaa
    45601 tgctgattcc ttctttgtgc tgacgcaaag aggagcacta aagcgagtgg cgattgctga
    45661 tattccacag accagccgag ctaacagagg tctgccggtg ttacgagaat taaagaccaa
    45721 gccacacaga gttttcttgg caggaatggt aaaaggagat actacaacag gtaccattga
    45781 cttatttaca catgattcag aggacacagc tagtgaccag caattagagg ttattagtaa
    45841 gactggtcaa caataccagc ttgctctcaa tagcctgtct ctatcagata ggacaagtaa
    45901 tggctccttt atttcagaga gcatttcaga tcaggaggtc gctgctgcaa ggctcatcta
    45961 gccaaagctt tttcgctgta ccagtgaggg ctctgagtct ttcatcgaaa aaagatgcaa
    46021 aacaatgaag aaaagaatac aaaaagaaaa gaggtaggat aatgacaaca gctattgatt
    46081 gggaaaactt aggctttgaa taccgtaagc tgccatttcg ctatgtatca tattacaagg
    46141 acggcaaatg ggacgcaggt cgcttaacag aagatgctac cctgcacatc tcagaaagtg
    46201 caccagctct gcattatggg caacaagcct ttgaaggctt aaaggcctat cgcactaaga
    46261 acggctctat tcagctattt cgcccagacc gcaatgcagc tcgcttacag gcaacagctg
    46321 accgtttgct gatgccacag gtatctaccg agcaattcat tgacgccgtt aagcaagtgg
    46381 taaaggcaaa tgaggatttt gtaccgccat atggaactgg tgctaccctt taccttagac
    46441 ccttgttaat tggtgttggc gatattatcg gtgttaagcc tgctaacgaa tatatattta
    46501 tagtttttgc catgcctgtt ggcaattact ttaaaggcgg gcttgcgccg accaacttta
    46561 tcgtctctga ggattatgat agagcagctc cttatggcac tggagctgcc aaggttggtg
    46621 ggaactatgc aggtagctta ttgccaggaa aagcagctaa gacagcaggg tattcagatg
    46681 tgatttacct agatccagca actcacacta agattgaaga ggtcggagcc gctaatttct
    46741 ttggcatcac tgccaataat gaatttatta cgccgcttag cccatcaatc ttgccttcaa
    46801 ttaccaaata ctccttactc caattagccg aagaaaggct tggtatgacc gctattgagg
    46861 gtgatgtgcc gattaatgat ttggaccgat ttgttgaggc aggagcttgt gggacagctg
    46921 ctgtgatctc accaattgga ggcattcagt atcaggataa gctacatgtc ttttacagcg
    46981 agactgaggt tggtccagtg acacgtcgat tatacgatga gctggtcggt atccaattcg
    47041 gtgatatcga agcaccagaa ggctggattg tagctattga ttaaaataag tgaagcttgc
    47101 tattgcaagc tcttttgatt ttgtgtaaaa tagacaaggc gaggtgaagt gatgagtaaa
    47161 aaagagaaaa aaattgaact gcaattatgc gatcaacaag taacagtcaa caataccaag
    47221 atagacggtt atcagttaca aattggcaag cgtgtcgttg gcgagattgc agagcttgat
    47281 ggcaagtttg ctgtcttaaa agacagcaca gtagatgctt tttttaaaac attagagcaa
    47341 gcagttgaaa atattattga aaactataat ttgaaccact aaaaatgctt aaaaagactt
    47401 gtcagcttac aaaaactatg gtagaatagt ttttgttgtt acggaaagat agcgaagagg
    47461 ctaaacgcgg cggactgtaa atccgctcct ttgggttcgg gggttcgaat ccctctcttt
    47521 ccatgcctaa gctattaggt tcattgtttt aatgatgata ttggggtata gccaagcggt
    47581 aaggcaaggg actttgactc cctcatgcgt tggttcgaat ccagctaccc cagtcagagg
    47641 tatcagatta gcgtctgaga tcgtcaagga taaaagttgt tgtcattgcg ggttaccttg
    47701 agaaaatata ttgttatcaa aagctagcat aagctagctt ttgttggagg attttttaga
    47761 atgaatgaat ttgaagattt gctaaacagt gttagcgaag tcaatcctgg tgatgttgtc
    47821 actgcggagg ttttgacagt tgataacggt caagcaaacg ttgttattga aggcacaggt
    47881 gttgaaggcg ttttgacact tcgtgaattg actaacgatc gtgaagctga tattaatgac
    47941 tatgttaaag ctggcgacac cgttgaagtg cttgttcttc gtcaagttgt aggtaaagat
    48001 actgatacag ttactttcct agtatctaaa aaacgtttgg aagctcgtaa ggcatgggac
    48061 aagcttattg gtcgtgaagg tgaagtcgtt actgttaagg ggactcgtgc tgttaaaggt
    48121 ggactttcag ttgaatttga agggcttcgc ggatttatcc ctgcttcaat gattgacact
    48181 cgttttgttc gcaatacaga aaagtttgtc ggtcaagaat ttgacgctaa aatcaaagaa
    48241 gttgatgcag cagaaaaccg ctttatctta tcacgtcgtg aggttgttga agaagcagct
    48301 aagcaagcac gtgacaaagt cttttcaaca ctttcagaag gttcagtggt aactggtact
    48361 gttgcgcgtt tgacaagctt tggtgctttt attgatcttg gtggtgttga cggtcttgtt
    48421 cacgtaactg agctctcaca tgagcgtaat gtgtcgccta aatcagttgt ttctgttggt
    48481 gaagaggttg aggtgaaggt acttgctctt gatgaggaag caggtcgcgt atcactatca
    48541 cttaaagcaa caacacctgg accttgggat ggcgttgagc aaaagcttgc acaaggtgat
    48601 gttatcgaag gtaaggttaa gcgcttgact gactttggtg cttttgttga ggtattacct
    48661 ggaattgatg gacttgtaca catttcacaa atctcacaca agcgtgttga aaatccaaag
    48721 gacgtgctta ctgtaggtca agaggtaact gttaaggttc ttgacgttaa cgctgctgat
    48781 gagcgtgtat cattgtcaat caaggcactt gaagagcgtc cagcacaagc agagggtgaa
    48841 aaggaagaaa aacgtcaatc acgtccacgt catcaaaaac gtgaagctaa gcgtgattat
    48901 gagcttccag aaacacaaac tggattttca atggctgacc tttttggtga tattgaatta
    48961 taatactata aaaa
//
LOCUS       DARYVE010000010        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYVE010000010 DARYVE010000000
VERSION     DARYVE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TVW25_000492"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TVW25_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1378158.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TVW25_000493"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TVW25_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TVW25_000494"
     CDS             1286..2599
                     /locus_tag="TVW25_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1378159.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TVW25_000495"
     CDS             2700..3587
                     /locus_tag="TVW25_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1378160.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TVW25_000496"
     CDS             3600..4430
                     /locus_tag="TVW25_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1378161.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TVW25_000497"
     CDS             4446..4901
                     /locus_tag="TVW25_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1378162.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TVW25_000498"
     CDS             4926..5576
                     /locus_tag="TVW25_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1378163.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TVW25_000499"
     CDS             5605..6525
                     /locus_tag="TVW25_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1378164.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TVW25_000500"
     CDS             6540..7424
                     /locus_tag="TVW25_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1378165.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TVW25_000501"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TVW25_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TVW25_000502"
     CDS             complement(7738..8562)
                     /locus_tag="TVW25_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1378166.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TVW25_000503"
     CDS             8791..9564
                     /locus_tag="TVW25_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1378167.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TVW25_000504"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TVW25_000504"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1378168.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TVW25_000505"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TVW25_000505"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1378169.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TVW25_000506"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TVW25_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1378170.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TVW25_000507"
     CDS             12390..13052
                     /locus_tag="TVW25_000507"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1378171.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TVW25_000508"
     CDS             13045..13677
                     /locus_tag="TVW25_000508"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1378172.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TVW25_000509"
     CDS             13679..14950
                     /locus_tag="TVW25_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1378173.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TVW25_000510"
     CDS             14940..15878
                     /locus_tag="TVW25_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1378174.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TVW25_000511"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TVW25_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1378175.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TVW25_000512"
     CDS             16830..19334
                     /locus_tag="TVW25_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1378176.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TVW25_000513"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TVW25_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1378177.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TVW25_000514"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TVW25_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1378178.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TVW25_000515"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TVW25_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1378179.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23125..23277
                     /locus_tag="TVW25_000516"
     CDS             23125..23277
                     /locus_tag="TVW25_000516"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378180.1"
                     /translation="MTEKSSPIRHKRLGKGLKKALLTTLSDTFGCPKKLFAVSILMEK
                     QSFENG"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TVW25_000517"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TVW25_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1378181.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAYL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TVW25_000518"
     CDS             24977..25831
                     /locus_tag="TVW25_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1378182.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TVW25_000519"
     CDS             26041..27237
                     /locus_tag="TVW25_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1378183.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYEAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TVW25_000520"
     CDS             27660..28181
                     /locus_tag="TVW25_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1378184.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TVW25_000521"
     CDS             28257..28628
                     /locus_tag="TVW25_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1378185.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TVW25_000522"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TVW25_000522"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1378186.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TVW25_000523"
     CDS             30244..31902
                     /locus_tag="TVW25_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1378187.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TVW25_000524"
     CDS             32071..32985
                     /locus_tag="TVW25_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378188.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TVW25_000525"
     CDS             32995..34026
                     /locus_tag="TVW25_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378189.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TVW25_000526"
     CDS             34038..35084
                     /locus_tag="TVW25_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378190.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TVW25_000527"
     CDS             35084..36019
                     /locus_tag="TVW25_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1378191.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TVW25_000528"
     CDS             complement(36648..38330)
                     /locus_tag="TVW25_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1378192.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TVW25_000529"
     CDS             complement(38332..38562)
                     /locus_tag="TVW25_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1378193.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TVW25_000530"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TVW25_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1378194.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TVW25_000531"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TVW25_000531"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1378195.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TVW25_000532"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TVW25_000532"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1378196.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TVW25_000533"
     CDS             41002..42030
                     /locus_tag="TVW25_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1378197.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TVW25_000534"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TVW25_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1378198.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TVW25_000535"
     CDS             complement(42888..44060)
                     /locus_tag="TVW25_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1378199.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TVW25_000536"
     CDS             44186..44716
                     /locus_tag="TVW25_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1378200.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TVW25_000537"
     CDS             44761..45348
                     /locus_tag="TVW25_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1378201.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TVW25_000538"
     CDS             45452..46174
                     /locus_tag="TVW25_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1378202.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TVW25_000539"
     CDS             complement(46216..46515)
                     /locus_tag="TVW25_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1378203.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TVW25_000540"
     CDS             46913..47500
                     /locus_tag="TVW25_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378204.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TVW25_000541"
     CDS             47639..>48181
                     /locus_tag="TVW25_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1378205.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13643 a         9419 c        11267 g        13852 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct acaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcata tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctacg aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga caaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYVE010000011        44665 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYVE010000011 DARYVE010000000
VERSION     DARYVE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44665
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            398..811
                     /locus_tag="TVW25_000542"
     CDS             398..811
                     /locus_tag="TVW25_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1378206.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1071..1652
                     /locus_tag="TVW25_000543"
     CDS             1071..1652
                     /locus_tag="TVW25_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1378207.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2062..2388
                     /locus_tag="TVW25_000544"
                     /pseudo
     CDS             2062..2388
                     /locus_tag="TVW25_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2457..4460
                     /locus_tag="TVW25_000545"
     CDS             2457..4460
                     /locus_tag="TVW25_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378208.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4457..5065
                     /locus_tag="TVW25_000546"
     CDS             4457..5065
                     /locus_tag="TVW25_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1378209.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5254..7980)
                     /locus_tag="TVW25_000547"
     CDS             complement(5254..7980)
                     /locus_tag="TVW25_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1378210.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7995..9281)
                     /locus_tag="TVW25_000548"
     CDS             complement(7995..9281)
                     /locus_tag="TVW25_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1378211.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9414..10472
                     /locus_tag="TVW25_000549"
     CDS             9414..10472
                     /locus_tag="TVW25_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1378212.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10487..12181
                     /locus_tag="TVW25_000550"
     CDS             10487..12181
                     /locus_tag="TVW25_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1378213.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12208..13599
                     /locus_tag="TVW25_000551"
     CDS             12208..13599
                     /locus_tag="TVW25_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1378214.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            13586..13723
                     /locus_tag="TVW25_000552"
     CDS             13586..13723
                     /locus_tag="TVW25_000552"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378215.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13919..16093)
                     /locus_tag="TVW25_000553"
     CDS             complement(13919..16093)
                     /locus_tag="TVW25_000553"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1378216.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16081..16974)
                     /locus_tag="TVW25_000554"
     CDS             complement(16081..16974)
                     /locus_tag="TVW25_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1378217.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17186..18136
                     /locus_tag="TVW25_000555"
     CDS             17186..18136
                     /locus_tag="TVW25_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1378218.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18146..19072
                     /locus_tag="TVW25_000556"
     CDS             18146..19072
                     /locus_tag="TVW25_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1378219.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19156..20601
                     /locus_tag="TVW25_000557"
     CDS             19156..20601
                     /locus_tag="TVW25_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1378220.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20949..21554
                     /locus_tag="TVW25_000558"
     CDS             20949..21554
                     /locus_tag="TVW25_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1378221.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21544..23268
                     /locus_tag="TVW25_000559"
     CDS             21544..23268
                     /locus_tag="TVW25_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1378222.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23268..24752
                     /locus_tag="TVW25_000560"
     CDS             23268..24752
                     /locus_tag="TVW25_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1378223.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24766..28209
                     /locus_tag="TVW25_000561"
     CDS             24766..28209
                     /locus_tag="TVW25_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1378224.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28360..29244
                     /locus_tag="TVW25_000562"
     CDS             28360..29244
                     /locus_tag="TVW25_000562"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1378225.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29370..30143
                     /locus_tag="TVW25_000563"
     CDS             29370..30143
                     /locus_tag="TVW25_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1378226.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30475..31557)
                     /locus_tag="TVW25_000564"
     CDS             complement(30475..31557)
                     /locus_tag="TVW25_000564"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1378227.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31616..32371)
                     /locus_tag="TVW25_000565"
     CDS             complement(31616..32371)
                     /locus_tag="TVW25_000565"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1378228.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32809..32979
                     /locus_tag="TVW25_000566"
     CDS             32809..32979
                     /locus_tag="TVW25_000566"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378229.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            complement(33641..33799)
                     /locus_tag="TVW25_000567"
     CDS             complement(33641..33799)
                     /locus_tag="TVW25_000567"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378230.1"
                     /translation="MACYSGRVKKLRQVAARSEWVVVPMGDSSTANKMEEAKKLAAFE
                     ATQTLFKL"
     gene            33886..33956
                     /locus_tag="TVW25_000568"
     tRNA            33886..33956
                     /locus_tag="TVW25_000568"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33918..33920,aa:Thr,seq:ggt)
     gene            34484..34738
                     /locus_tag="TVW25_000569"
     CDS             34484..34738
                     /locus_tag="TVW25_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1378231.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34760..35260
                     /locus_tag="TVW25_000570"
     CDS             34760..35260
                     /locus_tag="TVW25_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1378232.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35520..36104
                     /locus_tag="TVW25_000571"
     CDS             35520..36104
                     /locus_tag="TVW25_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378233.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36304..36867
                     /locus_tag="TVW25_000572"
     CDS             36304..36867
                     /locus_tag="TVW25_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1378234.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36880..39531
                     /locus_tag="TVW25_000573"
     CDS             36880..39531
                     /locus_tag="TVW25_000573"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1378235.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39626..39781
                     /locus_tag="TVW25_000574"
     CDS             39626..39781
                     /locus_tag="TVW25_000574"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378236.1"
                     /translation="MKKRVIGWLGVLVIGLMLGLIWWKWLVADRPLTQAGQGSHDHSS
                     DKGLSAA"
     gene            39744..40232
                     /locus_tag="TVW25_000575"
     CDS             39744..40232
                     /locus_tag="TVW25_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1378237.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40435..41235)
                     /locus_tag="TVW25_000576"
     CDS             complement(40435..41235)
                     /locus_tag="TVW25_000576"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378238.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
     gene            41746..41982
                     /locus_tag="TVW25_000577"
     CDS             41746..41982
                     /locus_tag="TVW25_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1378239.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
     gene            41975..42673
                     /locus_tag="TVW25_000578"
     CDS             41975..42673
                     /locus_tag="TVW25_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1378240.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            42873..43331
                     /locus_tag="TVW25_000579"
                     /pseudo
     CDS             42873..43331
                     /locus_tag="TVW25_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            43332..44306
                     /locus_tag="TVW25_000580"
     CDS             43332..44306
                     /locus_tag="TVW25_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1378241.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
BASE COUNT        12280 a         8909 c        10445 g        13031 t
ORIGIN      
        1 gaaaggagtg ctttcaaatg ttatcagggg agcatgatgg ctaaagagag acctcagagg
       61 aaactcagtc tttgaagcat taagacagct ttctcatatt ggttacgggt attagaaatg
      121 cgcttaatcg gtgtcaacag ttttcgtatt accatttaag acgtttcgac gacattttaa
      181 gacttaaata ctgaaagcag ctggtaatat gctatactgg tgccagttgc taaacatagg
      241 aaatattcat gtggacgaca gcattgatga aatatttaat gcttaggtac tggtagactt
      301 gcttatgttg aggctgaaaa aattaataga gtttgtgacg cagctattgg aggaataggt
      361 ggcgcactga cttgctaaga aagggcaagg tgttgtaatg cttaataaaa tgaagcgact
      421 acattatttg atgattttta ggctattaac tggtcagcta ccagctatta gcttgatggc
      481 tgttcttctt tcaaaagaca ttcataggct ttctttggga tcactgatta gttttgctat
      541 ctttgcggta agcactgctg cttctaatta ctatttttca cgagaaattg cgattgagca
      601 gttgaaggaa caaacacgtc ccaatctgtt attaactcag atcctgttta tagtggtgtt
      661 tatgattata ggcattgtgt caatctattg tggtctaagc tcgtctgagt tttataagca
      721 ggttattgct gtgatatgct cttttatatc atttgtcact atgggattga tgatttgggg
      781 gatcagatac gcaaaagctt atcgtcgtta atagcttgag gtggtactgg tacttgaaat
      841 cacctcctta accagttaat cataagctat agcactaggt atcagcctta aagcgacgat
      901 acctagtgtt tgtgtgctca aacgcttaaa atagcttttg agggggtaga gctgtctatc
      961 tgcaagcgat atgacaacct atttcattta gggatcaggc ttttttacta tcagtgtttt
     1021 tgacaaggcc cttgttttgg agtatactgg gaaaactagg agggctatta atgcgtagga
     1081 ttcgtttagc aaccttagca gatgctaagg ctttacttga tatttaccgt ccttatgttg
     1141 aggaaaccgc tgttaccttc gagtacactg tacctagctt gaccgagttt gagcgacgtc
     1201 tgtctgacat tatggtcttt tatccctgtc tagtagtgga agaggaggga ggcattttag
     1261 gttatgccta tgctagtcgc tttcatgcac gcgcagccta tgcttggtct gctgaggtga
     1321 ccatttatct ggcccaggag gctagaggga gaggcttggg atcagccttg tatcaccgtt
     1381 tggagggtta tctgaaaggt atgggaatct taaattgtaa tgcctgtatc gctagtacag
     1441 cgcatgctac gccttatctg accaatagca gtcaagtctt ccatgaaaaa ctcggttatc
     1501 ggttggttgg cagatttcat cagtcgggct ataagtttaa ccagtggttt gatatgattt
     1561 ggatggagaa actgctggga gagcatgacg tacgccctcg cccagtgatg tcatttaggg
     1621 attttctttg ccagaagcac cagtctgaat gacaccttat aaaagcttag attaatacaa
     1681 aaggattagg tcctgtcaga ggaagctaat ttttttgtat tgtttgacga gaagttttga
     1741 ctgataaccg caatcataaa aaaactcttc aggccctgtt ataaaatggt ggtagcagga
     1801 gatggttatg tctgagcttg tcactaggtc agctacagca gtcctagtgt catagcttta
     1861 aaaatgagaa aaaagaaatt attttttaag cttggtcttt ttaatatctt tttttgccct
     1921 tgacaattct gccaatgagc tgcaaaaaaa cttaagctct ttcccaaaaa gcttttatga
     1981 tatgatacac ttgtgttgta aaaggatcct gatactagtt aagatttttt tactttattt
     2041 taacaaagga gagtacacga catgaaaaga agtgtaaaat ggtttatgag ccttggcttg
     2101 gttggagctt tcgtagttgc tgggatatct aatgttaacg cagagactag gcaccctcat
     2161 ccaaagtata aggacacttg ggaatttgga attaccagtg ctagctgatc ttactcaaac
     2221 gcttttcttg gagttcctat tgggctagga agtagtgctt ctgtgacaga cttttgggga
     2281 aatgtaaata gtaaagatag tcaaaacaat ggttgggctc gtgccggtgt aaaaaagcag
     2341 tggaattggg ttcaagcaaa gtcatgttat ggctggtatc aggtttaatg ttttattgta
     2401 cgttttagtg gatgaagata ttatcctctt agtcaacttt tctcaaggag gtttttatga
     2461 ggtggagagc tacagttatc tgtattttcg ttctgctttt gacatgttta tcatttggtg
     2521 cggtcaagga gtatggcaat gatatcaaat accctgttca ggctgcattt tcattagtgg
     2581 cttcaaacaa agatgttgat aagggacacg ttttagacag gatcgaagcc ttagccgagc
     2641 aggaacatat ccaaatttat cgtccctact tagatcatac tggtaaagaa gccacctacc
     2701 tgtttgggac aaatgggaaa aagactgtct atagcagtaa tcgcaaggag ctcttgacaa
     2761 acgatcttag tggcatgtac tacacgacga ggtctcttcc ttcatcattt gaaaccgcga
     2821 tgactgaacg gggcttgacc tacaaaggtg ctgatttacc ttggtatctc ttgccttatt
     2881 attttttgtt cacaaactta cgatccttag ctatttggac cctctttttt gtgtttgccc
     2941 tcctcttgtt tgctgttaaa ttgatgtatg ctaaaaagtc tatgatacta agaagcctgg
     3001 gcttatttga acactatagc cgcaaggagt tgctacagga tttgttgctg atgggagcta
     3061 gctttgcggt tagtattctc ctcttcattc tctatcaagg cagtatctcc aatgtttttg
     3121 tcaagtcatt tacacttctg atcttgacta atgctgtcat tttattattg ctgatgcttg
     3181 ctgttcatgc tttatttttc atcaatatcc gttcgttgaa ggcgctagcc attctaaaaa
     3241 ataaacaagc aacccctttg gtcctctttg tctggttggt ggggatttgt ttgtctagcg
     3301 tcatttttgg gctttcccta cacaaaagct tggagactat aggaaaatct gccaatgaca
     3361 ttcaagttct aggaaaatgg gataaagcta aggattttgc ggaaataaca tggctagata
     3421 ccttgagtac gcatactgat gacaatcacc aaattgatag tgattatttc aaggaagaaa
     3481 atcagcgcta tcaacatttt ctcctgtctt tttctgataa tgacgttatt tattcagcac
     3541 tttcaagcct taacgaaacc aatttacaat cagctcctga tgacttcaaa aaagagttaa
     3601 agaccaatgg ggttgatcca aggattgcgt caaaagtccg ttatgtcaat cagggattta
     3661 tgctaaaaaa taaagacatt ttccctaaca atgattacgg aaggccagca gctgatgctg
     3721 taggagtcat ttatatttct aaacatatga tgggagatgc tgacagcatt ttaaacattg
     3781 tcaattatga atggtttcaa tatagcagcc taaaggctaa tcaattggtt gttcaagagg
     3841 ttcctgacgg acaaaagagc tttctgttta atcataagca agaccaacaa gacatttttg
     3901 ctcagcaaga agaagtgaat actatattag tgcagttaaa cttttcgttc atgacggagc
     3961 catcattatt gacgaagttt ggagaaatgg ctcaaaaatc tatctatcgt caggcgctta
     4021 ttcgtgatcg attaacacaa gcaggcttga cgaatttctc tagtttgacc aatgtttcca
     4081 atcatttgat tttagagcgc cataaaatcc taagccagct catcggaagt gttattgcct
     4141 taacggtcct tgccattgcc cagtgcttta tcatttatga atacattgtt tctctgatga
     4201 aacaaaaggc caaaaagatt tccgtctggt tcttgatggg gcaaaaaagc cttgttttga
     4261 ttggtagatt gttattgccc ttagctttgt gtttgtttct tgccatagga atgatgggaa
     4321 tccttactgg aaataggctc atggtactag gcattggcct gctttattta ggagaaatcg
     4381 tttgtatgtc cttttttgct tatcaggcta ttttgaagca tcggattcaa atcatcaaag
     4441 gagattttga catattatga ttgagataaa acagctttcc aaacattatg gaaaaaagac
     4501 aatttatgac aagcttagct tgacttttga ggccaatcgt tcttatgcac ttgtaggtcc
     4561 ttcaggatca ggcaagacca ccctattaaa tgctattgct cgccttgaaa agccagatag
     4621 tggtcagatt ttagtaaatg gtcaagacat ttggagcatg aaagagcaag attattttaa
     4681 ggattatttg ggctatgttt ttcaaaatta tgcactgata gaggaagaaa cagtctatga
     4741 caatcttaaa atgctggctc ctaaatctaa cattgtggaa gccttgcata gcgttggctt
     4801 agacagtagt tttctctcac agaacattta tgaattatca ggtggtcagg ctcagcgtgt
     4861 tgctattgca cgcctattgt taaaaaaggc ttgcattatt ttggcagatg agccaacggg
     4921 tgccttggac aaggaaacag gtgatgagat tattgagctg ttgcttagtt tggtgagccc
     4981 tgatactgtt ctgatttttg ccactcatga cccaaatgtg tttagccgcg ttgatgacat
     5041 catcgacatc tgtcatctac aatagaggca agctctgaga catttagtct ggactgtcga
     5101 gctacagcaa ttagcttgac aatgctgtta ttcctttgtg tcaggaagag attgctattc
     5161 ttctatagat ttttcgaata gacaatgctg aaagtcctta gcgttaatgc taaggacttt
     5221 tttgtgattt aggtcaaggt agtggtaatc tggttataga tgagctgatt cactcttttt
     5281 ccaagctagg gttaggattt cgcccttgcc aagctcagct ggtaggggtt catgctgatc
     5341 ctcttctagt aggctggtaa cccttgctgt gtggtctggg attgctaggg taagagcgca
     5401 ggccttgtca tttgatacat tatagctgcg cgtgattagg gcattatcgg ataggcgacg
     5461 cttgaaggct gtgagagcaa cgtgatcagt tgctcctttg atgtaagcat attgagctgg
     5521 cagctggcca gaatgcctct tggtttgcgc catggtgact ggtacctgag cctcctgagc
     5581 tcgccaatag ctggcaaagc gtgtggtagc gttaatgctt tcaaagctaa agctgacagt
     5641 ctgttgaccg aggcattgag catcaggggt tgggaagtag ccccaatctc caagctcacc
     5701 gacgcttcgt aggagcgtga tagcgatggt attggtatct ggtaggattt cgtattcatt
     5761 gaggccgtaa ttgcctacag tgacaccagt cctaccatca aaaaggctga caaaggcctc
     5821 ctgatgctga ggattggttg ggtttttcca gaattgggca ttggtatgat taggccgctt
     5881 tacggtttca aaaatactat ctgcaaaatg gtggtctgtc tttaaatggg ttggaaatag
     5941 cacgcgcaag cggtggtttg tcatttgatt gttaaagctg gtctgaaatt gtaggcgtgg
     6001 gctgtctttt tccatacgaa taactgttgt tactgtaaag ggcgcttttt cctgtgagcg
     6061 tttggcctga cgctctctaa tgtcaatgac agcctccatt tcagccttta gacgatcatc
     6121 tgtagctaag ggaatatcaa aggtctgtgt caattcgatt tcagcaagat aggctgtgtt
     6181 ggtcaagacc cgcaacttac agctcccttg atgagcaagg taggggctat catgatctgg
     6241 ctggcgaaag atatattcgt taccaatatc accacaatcc tcgtattgga gacagctgtc
     6301 aaacctattg ccatttagct tgtcttcaat cgttagaagg ccatttgctg cgatgatgac
     6361 ttttaggaaa tcattttcaa gacagctcct gtcctgatga aagagcattt tgtcagtgtc
     6421 agttgcttgg caaggctgat cagtctcttt tagtgcaaga cattgccatg acatagcaga
     6481 aagagtcagt gggagcctta gctgtacctt gatggcaaag taggcttctc tgaaggtgcg
     6541 ctctggcagg gcataatcaa aggcgatgtc tgtgcctaag atttcagcct cctctatgat
     6601 cctgccagct gcgtcaataa cctgaaattg tggctgtctt gtctctaggt attcctttgc
     6661 ttcttgataa acagctttag gcagtcgttg cccaaatgga aaaatcttcc atgtcagggt
     6721 gaggtcggag accgtttttt tctcatgacc gcaggtattg aagaggacaa aaggacagct
     6781 atcctctgga aacatggagg tatcaatagc ctcagctatt tggttggcag aacgctctgc
     6841 taagtaagtc cccacctcat aggctttatc aaagcgaggc atcatctcct ggtggacact
     6901 atcaacacta cagccacaaa tggagtcatg agggtggttt tgcatcaatg ttttccaagc
     6961 atagcgcagc tggtcgtgag gataggtacc tgtgacctca aaggccatcg tggcaagagg
     7021 ctctgtgata ttttcaagct gacgagacac tctggtatta gcctgcttga ggtaaattct
     7081 agcagaggca gtgttggcta aggtatacca gccgtccgtt tcttggctgg tcatctcacc
     7141 agacacaatt gagagctcct caggcagctc ctgacttaaa tcagccaaat agtcctcaaa
     7201 gcaagagtgg acaaagtcgt aatcagggta gagcttattt gcaagggcaa ttgccttggt
     7261 aacgtctagt tgaacaggct ggtgatcaac cccattcatc atcagcaggt gcctggtaga
     7321 agcaaagcgc tcagcgtctg ctagcttttg atcccagaat tgtcgagcct ttttctcctc
     7381 ggttgggatt tcgttgccat tgctgtacca attggcaaat aataagccga gaatgcggct
     7441 atcatcaggt ccctgccaga tcatttcaga aaattgggag ctgtattttt cgcttgtatc
     7501 cacttgattg ttaaagcctg taggcctgat accacgtcca aaggcagcgg catttagccc
     7561 tgcttttcgc attagctgtg gtgtttgtcc catatttccg aaggtgtctg gaaaataacc
     7621 cagtggaacg cttgcccccc attgctcaca gtcctctttg ccaaccagca tgtttcggac
     7681 attggactca ctgctggtca aaaaggcgtc ctgtaggata taaaaggggc caatacgtag
     7741 cttaccagcc tgaatggcct gtctaatctc ggcctcacgc ccaggcttga cctgcaaata
     7801 gtcatctagg ataatggttt gcccatctag atggaagcta tgaaaatcag ggtctgtttt
     7861 aaaaaggtct agtaaatcgt caattaactg gatcaagcgc atgtggtgct gctcataagc
     7921 catgtaccat tcgcgatccc aatggctgtg tgaaatgata tgtacttttt taggtgtcat
     7981 cactgactca ctttctaagg gctaatggta aagcccagat aatcaagaag aagctcacaa
     8041 aacatcatgt ttgcccatga gaaccattca cgtgtatagt gactcggatc attgacgtca
     8101 aagccctcat gcatcaggtg ggtgcctgcg tcagtagcca ccagtaaatc aagtatatct
     8161 gctttatctt tttgatcaag tgcagttaag ccctgaaggg caagtgcaat atgccaaata
     8221 tagtttggtg gcgtgtggga ggagccaata ccagaagcag cactgccttg gtaataataa
     8281 ggattttccg ggcttaaaat ggtttgacga gtggctaggt aaatagggtc gtccttggca
     8341 caaaagccaa gatagggtgc cgcaaggagg cttggaatgt tagcgtcgtc catgatagta
     8401 tagtgcccca ggccatctac ctcataggca tagatgatct ctccttggct gttggttaca
     8461 agagcatgct cctcaatccc tttttgaatg gcaagcctaa gtgcatgagc tctcctagca
     8521 atcgtttgat ccttaaagag atcagtatag agcccttcaa gataggataa gacgacagca
     8581 gcaaacatgt tggacggcac gaggtagccg tattggcagg catcatcgct tggtctaaag
     8641 ccagaccaag tcatgcctgt ataggcaaca ggagctccct taccgttgtg ggtcaaggta
     8701 tcctccttac gccaggtgtc gcgctcaaag ctgtaaggag aggcagtgtg gtcttgctct
     8761 gtgctccaga catcaaggat cagcttgatt cctctgtgga aatcctcatt gaaatgctct
     8821 gtacagtctg tctctcggta gagcagatag gctaactgga tcggatagca gagggaatca
     8881 atctcatatt ttcgttccca aatccaaggt cccatctggg tgtggtctgc ttggtggccc
     8941 ttgctatttt cctcctcgtt aaaggcgttg gcataggggt caatgcaaat gtaacggaac
     9001 tgacgtttaa cgagacctgc tatgatttgt ctcatgccag catctgtctt ggctaaaaag
     9061 agataaggct ttagttgcgc agttgaatca cgcagccaca tggcaggaat atcacccgtt
     9121 agaagaaagc tggtcccatc ttcgtcgatt tttagggtcg tttccaaggt gttggcaaag
     9181 ctggctttaa aattaatggc ccagctacgg tgctcttcac cgcagagctc ttcaatcgtg
     9241 tccataaacc tgagcacact gctaggaata ggtcttgtca tatcatatcc tcctaaaaga
     9301 tatatcattt gatatctttt ttaattataa gatataactt tatttttgtc taccacttta
     9361 gaaaaggttt acaagtcttt tttttcgtga tatactgcta gagggagtaa aaaatgactg
     9421 aattactata taaaaagata tatcatttta tcaaggaaca aattgattca gggcaattac
     9481 aggcaggtga ccgcctacca acagaaaagg ccctatcaga gcaattttcg gtgagccgca
     9541 ttacctctaa gcgagcctta gtagagctgg agcaagaggg cttgattaca cgcagcagag
     9601 gtaagggcag ctttgtgacc gatggcccac caccgtctac tcagcctaat aaggacattt
     9661 tgttgatcct gccctttgct tctgattacg aattgggaga ttatgctaaa ggaatcatga
     9721 cggtcgttgc tgacaaaggc tatcgcctga tggtccagct tacaagtacg gtaagcttgg
     9781 aggagctagc tgattatgct ggtgtgattt attatccaga agacgttaat catagtattg
     9841 agctgctctt ttattgtgcc cagcgtgggc ttgctctggt gcttttggat aaggccttag
     9901 acctgtttga ctttccagca gttgttgcag acaataaggg cggagcctat gagttgacca
     9961 agcatttgat tgatcaggat tgccgtcgga tcatgtttgt ggcaactgct tcctttggtg
    10021 aggtttcctc tgttagagat cgttatttgg gttatttggc tgcgatggcg gaaacagagc
    10081 ttgaggccaa ttattttgtg aagctgaagt cagaaagcaa tgctgcttat cttgagcgat
    10141 tggttgatga gctgacggct gctacagctg aaaagactgg tttagtggtt gaaaatgatt
    10201 ggctagccat tcaattgatc caaaaaattc tacaggtcgg gctatctatt cctgatcagg
    10261 tagctgttgt tggctttgac aacagccaag cctctcagtt aatcagccct caattgacaa
    10321 cagctgcaca ggatttttac cagatggggc agcaagcagc gcaactattg atagagcggc
    10381 tgactcggcc tgatcagcag acggcgtctt gtcagcttcc tgttaaggtc tttatcagag
    10441 aaagcagtca aaagtcccta gaaatgctat aaaaaggaga agtgtcatgt ctatttatca
    10501 agccctcaag gactatcagg aggtgataac cagaggtgat tacctcgttt ttgacgcccc
    10561 tgtttcctgt cgctttgttg gtcgtttttt ccgatttgag aaccaaacag ctatgaagcc
    10621 tagtcttaca gcgtcagtct atgtcaactg ggttgaggag ggagcagctg acttgaccct
    10681 taagcacgtt tttaaccgca ccttagctag ggatgccttt accttgacca tttcagagga
    10741 taaggagctt gtgattgaaa gccaaaattt aagaggcttt cgctatgctc aggaggcttt
    10801 agaaaaggta atgactgtta aagagggcag gctttatttg ccgattgttt cggttaggca
    10861 tagtccgtcc tttgccatgc gtggtgtgat tgaaggcttt tatggcaccc cttggacgcg
    10921 tgaggagcgt ttagattgct tgagctttat tgctgataag ggcatgaata cctacatgta
    10981 tgcccctaaa aatgatgact atcagcgcag ccactggcgt gagccctatc cagaggattg
    11041 ggtggctcat tttagggatc tgatccagct tgccaaggaa agacaggttg acttttggta
    11101 catgattagt ccggggcttg attttgacta caccaaggaa gaggactatc agctgctcta
    11161 tcaaaaattg cagcaattgt tggatttggg tgtttgtcat tttggcctgc tgcttgatga
    11221 tattgattac caaatagtgg cagcagttga gagacgtttc aaaaaaacag cctatgccca
    11281 agcacatttg gcaacagctg tttaccagtt tttacagcgg cagcatgcag cccctgactt
    11341 ggttgtctgt ccgacagagt atgataatca tcatgactct ctttatttag cagagttatc
    11401 agaggctatt cctgctgagg tggctttttt ctggactggc ccaagcactc tggccagtca
    11461 gatttctcag gcagatattg agacaatagc agccatctac cggcggccca taatcatctg
    11521 ggataatatc cctgtcaatg attatcagga cgattctaag aggctctttt tgaccccgtt
    11581 tgccaatcgc tctcctttct tgtgtcagcc agactatcag gtcaggggga ttgtgtctaa
    11641 tccaatgatt agctgggaac tatcaaagcc gactttaatt gatatgagtc gctacctgtg
    11701 ggacgccaag cgttatcagc caagctattc ttggctagag gccttgagag actatactgg
    11761 agataaggct atggctttag cgcttttgcg ctttgcttgg cataatggca atcgtcattt
    11821 gcacagggat ctcccctttg aggtggagga ggcccttatg cgtaaggaca tagctagctt
    11881 atctggttgg gtagctgagc tggtagagct ggtggataag ctgaaagagc ttgatattcc
    11941 tgcgtttcaa caggctattg ctccttggtt tgatcgggct aaggctgatc agagcttttg
    12001 gagggttatt ttagagcaag cgcctgatct tgagcagcaa tatgctgagc ttcaggagca
    12061 aaggcatcga attggaagca atattccaag ccgcttttat cagttgcact atcttcagga
    12121 gaatagcatg ctaggcaatc aggcacaggt cgctgaagct agagctgagg attatactta
    12181 attagtttat aagggagaac aagggacatg ctagagtttc cagaaggatt ttggtgggga
    12241 agtgctacat caggccctca aagtgaaggc tgctttcaaa agccgcatcg caatttattt
    12301 gattattggt atgagcaaaa tcctgagctg ttttatgatt atgttggacc tgatacggct
    12361 tctgattttt ttcatcagta tgatcaagac ctagctttat tagcgtcttt gggtcacaat
    12421 tcctatcgga cctctatcca gtggacacgc ttaattgatg attttgagac agccacgatc
    12481 aatcccgatg gactggctta ctataacagg gtgattgatg cctgcctagc acatggtatg
    12541 cgtccggtga tcaatttgca ccattttgat ttgccaattg ctctttatca gaaatatggc
    12601 ggttgggaat caaagcatgt tgtggatttg tttgttgcct ttgctagagt atgctttgag
    12661 cagtttggcg atcgcgttaa ggattggttt gtacacaatg agcccatggt tgtggtggag
    12721 ggctcatacc tgctgcaatt ccactaccct gccattgttg atgggaaaaa agcggtacag
    12781 gtggcttata atctagcact tgcaacggct aaggttatct gtacctacca agaacaagca
    12841 gcagagctga gcaatggcag tgttggtacc attctcaatc tgacaccgat ctatccggca
    12901 actgattcag aggctgatct tgctgctgct catgttgcag agctgtggca caatgacctc
    12961 tttatgtctg ctgctgttta cggtagcttt ccaaaggagc tggtagcaat actacaaaga
    13021 gatggagtgc tctggcagtc cacaccagag gagctggatc ttatggctgc ttatacggtt
    13081 gattacgtgg gcattaattt ttaccgccct aagcgcgtga aggcgccaga ggttattcct
    13141 gtgattagcc cttcctggag tcctgagtgg tattatgatg cctatctgat gccgcagcgt
    13201 cgtatgaatg tggacaaggg ctgggagatt tatccagagg cggtctatga tattgctcta
    13261 aaaatgcgtg atcagtatag gaatatccct tggtttttat ctgaaaatgg ggttgggatt
    13321 tcaggagagg atcgttaccg agatgagagc ggacagattc aagacgacta tcgcattcag
    13381 tttttaaaag agcacctgac ctatcttcat aaggggattc aagcgggctc taattgcttt
    13441 ggctatcatg tttggacacc tattaattgc tggtcttggc taaatgccta taaaaaccgt
    13501 tatggtctgg tagaaaataa tcaccgcact cagcgtcggc gtgtgaaaaa atcagggtat
    13561 tggtttaagg aggtggcaga ggcaaatgga attagctaag aaaagaagaa aaacacaaaa
    13621 gccagcccaa tctcctttaa agctaggttt agagaagcta agagagattt tacaggagca
    13681 gctagtagct ttagcggttt tacctgctag ggtgatgggt tagcataagg gcttgctgat
    13741 gagctatgcc agtgatagcg attaaggaat gtaaaagagg atttcctaac atcataacta
    13801 tccgtctaac gggtgattta ttgtttcgta cctacggagc gaaacggact aaagtcacat
    13861 aactaaaagc atgtcatggc ttgctgtagt acgagtgatg acatgctttt tttagctttt
    13921 aacgggttag ggagtagggc aggtcctcag ccgaatagtg cttgagtggg ggaactagtc
    13981 ccagctgaaa gtcgagctga cagccctgaa tcagatcatc atgattgatg tagagcttgt
    14041 tgtagctagc ctgattgagc ttgacctctt tgacaaattg gtattgaggg acattgcccc
    14101 tacagctgat ttggatagta ttgccatttg gcagataaag ggttgcctga tctacagttg
    14161 gaataccaat caggtattgc ccagttcctg gtgtaacagg gtaaaggcca aggctgttta
    14221 acaggtacca cgcgctcata ctgccattgt cctcatctcc tgggtagcct gtatcggtaa
    14281 aggcatgact gagcagattt ttaaggatta gctgactgta ttgtggctga ccgatatagt
    14341 gatagagata ggggaggtga aagcttggct gatttgagat agcaatctga ccaaaatcct
    14401 gtgcggctag ctcactcatt tcgtggattt caaagccata gctgtgaacg tcaaacacag
    14461 gctcatgatt gcacagctcc tcaagtcttt tggcaatggc ggcgtttcct ccgatcagtc
    14521 gaatgtaacc tagaatatca tgataaaagg caaatccatt ttgataatag gagccctcgg
    14581 tgtagtcctg cccccagtgg atagggttaa agccacattg ccattgccct tgtcgatcct
    14641 tgcttttgag gtagccggta tcagtatcga ccaaatggcg gtaattgagt gatcgcgtgt
    14701 ggtattggtc actaagtgct gtcttgccca gaagggcagc tacctggccg atacaaaaat
    14761 cactataagc ataatcttga gtctgattga cgctttcctg gtagctattt ggcagatagc
    14821 ctagctcttg atagtcttga ttgcccttgc ggccatagcc tgttccttga ctgtctgtat
    14881 tggcagttgc cagcatagcc tctaaaagct caggcatcag gtcttttctg atgcctttga
    14941 cagctccatc agcaataaca gcatcaacca aggttccagg catcaggcct cgctcatctg
    15001 gagacagcca ttttggcaga tagttggtgt cctgataagc tgacaagagt ccctctaaaa
    15061 tatcagcata aatctcaggt gcaattagag acagcaaagg atagacagat ttataagtat
    15121 cccaaaagcc attgttggta tagtattttc cagcaacagg tctttgactt gttgtattat
    15181 agtgaatcgc ctgcccggtt gcagtgattt cataccatct ttggggaaat agcagggctc
    15241 ggtaaaaatg ctggtagtag gccttgacct tatcaaagtc tttatcctta atgtcaatac
    15301 gactgaggta gctgagccac tccttgcggc tgtattcaag gcttttttca aatgatctgg
    15361 ggaaatccct ctgccaattg agctgagctt gatcaaagct aataaaagaa gcagccgccc
    15421 taagctcaag atgtttgagg tcatcagcaa attggagata ggtaaaggac gtcttgctgc
    15481 aatcatcaag agatttggag tttaagtctt ctccgataag cttttttagc acagggctgc
    15541 taaactgaag ataaacaaac atggctaggt ctttatcctg acagtctgtg atgttttgca
    15601 cacagccaag gattgtttta ccatcagctg tcacctgcca ggagcttttt ccggggttat
    15661 ggataatcaa gcctgctttg ccattatcaa aggaaaaatc acaatgaaag ctgtaggcag
    15721 ctgctgttgc tcgcgtcaaa atccgatgtc tctggctaaa aatctcaaga agatgaggcc
    15781 gaaaagctgc ctccttggga cgataggagg tctgattatg aaacacatct cccttggtca
    15841 gcggtccgct gactggaaga aaagtaaccg tcgcaaaatc accgacccaa gggctgggtt
    15901 gatgtgtcaa gcgaatacct gaaaagctgt gatcatcggg gtgaaaccac caagcccctc
    15961 gatcttgact ggtttcgacg cttagataat gcatgccaaa gggaacccct gtcaatggca
    16021 ggcaatttcc ctgtgaaaaa tggtagtgat tggttgttcc aaagcgggtg tcaatgaagt
    16081 ctaatcgatc cacatctcgt cctttctatg ctcttgcata aaatcaatag aggcacctag
    16141 taggttggcc tcgtttttaa agtggcagat agcaagctgc ggtctcaaat cagaaatgct
    16201 gactatctga tagagcttat ccagttcagc ctcaagggca ggaagaagaa agtcagcctg
    16261 agagacaccg ccaccaatta ggatcatttc aggatcaaag gcatgctgga tattaaacac
    16321 ccccattgcc agactttgaa gaaagacctg tctttccttt agggccacag gatctccttg
    16381 atcagctagc tctaagacct ctttaccggt gtaactttta ccatcattta tgatctgact
    16441 atagcgcttg gccatattga ccacagtgcc taattcgctg aaggtttgat aacgctcatt
    16501 catgaccata aagccaaact cacctccaaa taaatgggca ccgtaatgaa tcctgccatt
    16561 aatcactagg ctacctccaa caccggtgcc aagtaccagc atggcaaggc tgctagtgcc
    16621 ttgtcctgca cctagagcag attcggcaag agcagcacag ttggcatcat tttcaatcga
    16681 aaccggcaga cctagtcgct cctcaaggca ttgctgaatg ggaaagccat gaatataagg
    16741 cagtgcactt gctccctcga tgatacctgt tgctttattg acagctccag gggagctaat
    16801 ggcaattcct gagagctttt ctgtgcggta gtaagccagt cgctcgtcaa gcatatggta
    16861 aaagtcctct aggctttggg gagttgggcg actgctttgc ttttttagcc tgcccttgtg
    16921 acaaatagca aatttgatgc tggtgccgcc tatgtcgata cataataagg tcattgtaat
    16981 tcctcctata acaggtatat taccaattag ctacccttag tatgacagat tttgaagtgc
    17041 ttgaaaagac tttctcggca ttcctatatt ttgtgctatg atacctataa tttgtgttat
    17101 caaacctata atttgttgct tgttctatgt gtaagcgctt gatatacttg aagcatcaat
    17161 tgaaaagcaa agggaggttg ggaagatgac gacaaagatc agcagcaaga aatccttttg
    17221 gaaaaatgtg atcaaatacc gcgctttgtt gctgatggta ttaccgggat ttgtctggtt
    17281 catctttttc ttttacattc cagtattagc taatgtagtg gcttttaagg attttcatta
    17341 ctcagcagga ggttttatgg aaagcctgaa agaaagtccc tgggttggct tagataactt
    17401 taaatacctt tttgcctcta aggatgcttg gttgattacg cgaaatacca ttgcttataa
    17461 tcttattttt ttactattta acgtcttttt tgccatcgct ttcgctatta tcatgagtga
    17521 gcttcgaaac aagaaggctg ttaaggtcta tcataccatg tccttactgc cttatttctt
    17581 atcatgggtt gtgattgagt attttgtttc tgccttttta aatacggata agggctttat
    17641 taatcagctg ctcattgata gcggcaatag cccaatcaaa tggtattcca atcccacctg
    17701 gtggcccttg attttacttt tcatgagtgt ttggaaagga cttggctaca acagtatcat
    17761 ttattacgca tcggttaagg gaatatcaga cacctactat gaggcggcta tggttgatgg
    17821 tgccagtaag tggcagcaaa ttagacatat caccattcca cagcttttgc cgatgatgtc
    17881 tatcctattg attattaata ttgggagtat cttcaaatct gactttggct tgttttatgt
    17941 gattcctaaa aattcaggtc ctctttacga tgttaccagt gttttagata cctatgtcta
    18001 caatgccctg acagctactg gtgatattag tatggcttct gcggccagtc tttatcaatc
    18061 tgtggtcgga acctgtatcc tgctcatcac caatgctttt gttcgtcgta tggatcccga
    18121 tgcagcctta ttttaggagg aggacatgga gaaaaagaaa actgttaaaa gggtcaacgt
    18181 cagaaccttt gacccaaaaa ccaatgctgt ctttaatgtg ttaatcgctc tttttgccat
    18241 ctcttgtatc attcctttta tctttgtgat gattatttcc ttcacagatg aaagctatct
    18301 gatcaatcat ggctatagct ttttcccagc tgcttggtcg acaaaggctt atcattatat
    18361 tttccaaggg gctatgtctc atcggatcat aagatcgttt gcggtgtctg tatttatcac
    18421 cgttttagga acctttatca ataccacaat gacctcaacc tatgcttatg ccatctcaag
    18481 accttatttt ccctacaggc gtttttttac catctatgcc ttgatcacca tgctttttgc
    18541 accgggtatg gtagccaatt atttggtggt gagtaacctg ctgcaattaa aggatacggt
    18601 ttgggccttg attttaccga tggctctggg accctttggc attttggtga tgaggacctt
    18661 ctttaaaaag accgttcctg atagtattat tgaatccgct cgtatggacg gcgcaggtga
    18721 attgatgatt tttatgaaaa tcgttttacc tttggcagtt cctgggattg caaccattag
    18781 cctgttctca gccttaacct attggaatga ttggttcaat gcgctgctct atgtgcaaag
    18841 cgagagcctt tacccgatgc aatacctctt gatgaagatt caaagcaata tacaggcact
    18901 agcccaaaat gctggcatga gcgcccagct atctgatagc ttagcctctt taccaaagga
    18961 atctgtccgc atggctattg ttgtcattgc aactttgccg atcgccctaa cctatccttt
    19021 ctttcaaaaa tactttgttg gaggactaac catcggcggg gttaaggaat aatcacccat
    19081 ttggaatagg tcatacagct gaccgttcca atgattctgt tatcaaaaaa agaaattatt
    19141 ttaggaggct tactgatgaa aaagtggcaa acaatcttat gtgtgacggg agctgtgctt
    19201 gcagctgcta gcttgacagc ctgtggaagc aaatcagctt ctaaggacgg tgaggtgaag
    19261 ctattgatgt atcaggtggg agataagcct gataactttg atgagctgat gacaattgca
    19321 aataaacgta ttaaggaaaa aacaggggca acccttgatt tgcaatacat tggctggggt
    19381 gattgggacg acaagatgag gatcattatt gcgtcaggtg aaaattacga cattgccttt
    19441 gccaacaatt atgtggtcaa tgctcaaaag ggtgcctttg ctgatttgac taagctaatg
    19501 ccaaaatacg ccaagaaaac ctataagaac ctagatccgg cctacattaa aggaaatacc
    19561 attgacggta agctttatgc ctttccagta gatgctaacg tctatgctca gcaaatgctg
    19621 tctttcaaca aagaattggt agacaaatat ggccttgaca tttcaaacat caattcctat
    19681 gcagatgctg aaaaggtctt gaaacaattc cacgaaaaag aacctaatac tgctgccttt
    19741 gcgattggtc aagtctttag catgtcaggt gactacgatt acccattgac caaaaatcaa
    19801 ccatttgctg ttaaaatcga tgaaggcaaa ccaaccatca ttaatcagta cgaagatgag
    19861 ccctttaaag caaacctacg cttgatgcat aaatggtata aggaaggctt gattccaaca
    19921 gatgcagcaa ccaacacaga aggctacccg cttgaaggca atacctggtt catgcgtgaa
    19981 gaaacccaag gtcctatgga ctatggcgat accatcttga ccaatgctgc tggtaaagac
    20041 attgtgtcac gaccattgac aaagcctctt aaaacgacct cacaagccca aatggctaac
    20101 tttgtcgtgt caaatgtgtc taaaaataaa gaaaaggccg ttgaagttct ttcccttctt
    20161 aacagcgacc cagaattgct aaatggtctt gtttatggtg ttgaaggcaa ggcctgggaa
    20221 aaggttggcg acaagaaaat caagctgctt gatggctacc aacccaaaat gcacatgggt
    20281 gcttggaaca ctggtaacaa caagatcctc tacacccaag aatcgatcac agatgatatg
    20341 attgcaaagc gtgaccaatc aatcaaagac gctaaagagt ctccgatcct aggctttacg
    20401 gtagatacca aggcaatcaa aacggagcta tcaaaaatct caaacgtgat gaaccgttat
    20461 aaagctagta tcaatactgg tacagtagac cctgatgaag ctcttccaaa acttctttca
    20521 gaccttaagg acgctggttg ggacaaggtt caaaaggaag tgcaaaagca attggacgac
    20581 tttgttacaa aaaataaata aggcaatgga ctttccttgc aaggtggtaa gaactgggga
    20641 cagcctcagt tctttttagc tcaagcaggc atacaagagc tgacagataa ggcctctctt
    20701 agaaaaaagc cagagcctgc ttgcaaggca gttggtccac caaagccctt gctgacaagg
    20761 ttttaccagc cttagtcggc tgtcctcttt ttattaagct tttgtcacaa ttagagtaaa
    20821 atatgctata ttagaagtat ctcatcttat catcatgaca gctaagacct tagtcatctg
    20881 gctgagggat cgttgcttct cttagggcgc tattggtcct acaaaggata ctagaaaagg
    20941 ataatcttat gacaggaatt gaaaaagcct gctttctcat ctggaaaatg atgcagctaa
    21001 cccttatatt tcatttgctt tccttatgtg gtgctgtgat ttttggagtg gggccagctt
    21061 ggcagaccat tgttaccttg tttttggaga ccagtcagca ggagaaacat tattcgctca
    21121 agcgggcctt tcagatatgg cgtcgggtct tcaaagaggc caatctcagc tttttcttct
    21181 ttggattatt gctattattg ctgaatacga gcctgtactt ggccattcaa tttcaatcgc
    21241 tgctgtggtt tagcctatcc tttattatca tgtttgtcat ggtttggctg gtgatgattg
    21301 tgatttacat gaccttttat gcagtgacct atgaaattgc tttttgggag aatctcaagc
    21361 tgtcttttat cagtattttc ttgaatgcca ggcagttttt gttgaccctt gtggttttag
    21421 ctggagttgc ttggtttact tggcagtata agggcttgta tctttttctg agctttggtg
    21481 cgctggtttt gttgctggat atggtcacca agcctaatcg tcgcatggta gatggagtca
    21541 ttgatgacaa gtaaatcttt aaagcggttc ttgatggagc atattaagca gggcttttta
    21601 attaaccgct tgatgaaaat atatagcctg tttatcgtgg ctctctttag cttaagtgcg
    21661 gttggtctaa gcacctattc gattcgaaat acctaccaaa tggttgacaa tcaaatgcaa
    21721 atgcggctag atgagaccct agcaaggcta caatctcaaa actatattac cctgcgcgtg
    21781 ctggagcagc tgatcgggcg tccagaggat tatcgaaatc tgtatcagta catgatattg
    21841 acccctaatc aatatcttac taaggttttt gaggattggg gtgagggcaa aaacacacct
    21901 ctgttttcag agcaggtcag aaggcttttt gatttgtatc cagatttaga tgggctgacc
    21961 ctgatgctgg acgatagcac gtcctatttg tatgcagata ggtcgattaa gaccggccgg
    22021 ctcttatttg gtaagcctca gacgctaaag ggcaattact tagtaaggtc cattcgccac
    22081 cctgagtcag gtgatgttac aggccgcctc tatctgcact ttgcaagccc cagcacgatg
    22141 ctacagcctg agcagcataa gtatctagcg acctttgcct ttgattacta tggcagagag
    22201 ctctttcatc agggaggcgc tgcctttccg gagcttgaag caggtcttaa aaaggcgcta
    22261 aaggcggatc aggctattga tttgacagct ctcagcaaga gctatcatat tcagtacaat
    22321 cgctcgggag acttgctggc ctatgtggcg gtcaaaaggt cttattttat ggaagaggct
    22381 gtgcgtacaa tgctcctgta tggccttggc tcgttattgc tagcttggtt attgctacag
    22441 ctccttttca gggtatttcg caattatatc cgacaggtct ctgagattac agatactatt
    22501 gaaatggttg cagctggtga tttgtcgtta aggattgaca acagtcatat ggaattagag
    22561 ctgtatcaca tttctgaggc gatcaatcaa atgcttggca acatcaatgc ctacatttta
    22621 gaaatctatg tccttgaggt tgagcaaaga gatgcccaga tgcgtgcctt gtcatcacaa
    22681 atcaatcctc attttttgta taacacccta gaatatattc gcatgtatgc gcttagctgt
    22741 cagcaggagg aattggcaga tgtgatttat gcctttgccg ctttacttcg aaataacatc
    22801 agccaggata aggtaaccac tctaaaagaa gagctggctt tttgtgaaaa gtacatctat
    22861 ctgtatcaaa tgcgctatcc agatagcttt gcctaccatg tcaagcttga tcctgtcgtg
    22921 gctgatgtgg aaattcctaa gtttatcatt cagcccttgg tggaaaatta ttttgtgcat
    22981 gggattgatt acagccgcta tgataacgcc cttagcatca aggcgctaga tgaggaggac
    23041 agtattttga ttcaggtgct tgataatggc aagggtatta gccctgagcg cttagtggct
    23101 attgaaaagg gcttagagga gccgcaatcg acggggaata gctctattgg gctgcaaaat
    23161 gtctatatgc gcctatttca caaatatcga gacagagtga cttggtccat gtctcaggca
    23221 ccgactggtg gctttaggat tcagatcaga attagaaagg aagcttaatg tacaaggtct
    23281 tattagttga tgacgaatac atgattttac agggcctaaa ggtgattatt gactggcagg
    23341 cgcttggctt tgaggttgtg gcaacggcaa ggtcagccaa agaagcctta gcttacctag
    23401 atgactgcgc tgtagatgtc atgatttcag atgtcaatat gcctggtatg acaggcctgg
    23461 aattgattga ggcagcaaga gatgtattgc cgcatttgca gaccttgatt ttatcaggct
    23521 atcaggaatt ttcctatgtg caaagggcta tggagctaga gactaagggc tacctcctaa
    23581 agccagttga taaaaaagag ctggtagcta aaatgctcta ttttaaggaa tggcttgatg
    23641 agcagagggc agcttctttg cgtcaggctg cttatcgtga gggcttgata aatctctggc
    23701 ttgctgatga attgagtgag aaagagtttt ttcaactaac gcaggagcaa cccgaggctg
    23761 agcttttagg ctttacggtg ttgtatgtgg attgcaagac ttttagccct gccttagaag
    23821 ccttttttga ggcctccaag cagccctttt acttaaaaaa ggcagagcaa aagaaggtct
    23881 atctagtcat tctattagga cagagccatc aggctaagcg ctttactaat acgcttcagg
    23941 agcgatttta caataccatc aatcagatca ttctaggaga aacggttgtt gattgggaaa
    24001 atgtgtatga aagctataat caggtcagaa ggagcttttt ttacaacagc gaggtgtctc
    24061 aggtagctgc taagaccaac gctaaaattg agctgccgga atcgcgattg cagttttttt
    24121 cctttaacaa gaccttgatg attggggacg agccaactat tgtctccaaa ttacaggcaa
    24181 tctttgagga gatgacagag ctaagcttct ctcctgagga cgtcaagcac gtctcttttc
    24241 tcttattttc agacatttat cgccaatttc cgattttaga tcgaacgacc tacctatcga
    24301 tggtcaagac tattcacgat agtcagtcca ttgatcagat cttatcagcc ttaaaaaagg
    24361 tgcttgagct gacaagcaaa agcaatcagc cccaaaagcg ctattctgat ctggtcagtg
    24421 aagccattac ctgtattcag gaggaatact ctcaggaatt aaccctcaag gctgtgtcag
    24481 atcgcttgca tatcaatggg gtttatttgg gacaacgctt taaaaatgaa acagagtgta
    24541 gtttttccca atacctcaat caggtgagga tccaaaaggc acagcaattg ctgctttaca
    24601 ccaataaatc gattaacgaa attgcctatg agacaggcta taatactaac cattatttca
    24661 taaaaatgtt caaaaaatta aatggtttat cgcccaagga gtttagagac cgttataaag
    24721 ataattatca agctataaaa ggaagctatt aagaaagggg gcgctatgtc tgtagagaca
    24781 atcactggtt caacggatca atctcatggg gatatctatc agcttcactg gattgataaa
    24841 gtagggcgct gccatgcctt ttcaaagggg tggcgctttc tgatggctga tttgcagctc
    24901 gctcaggagc cattttttga tgattcggac tggcagcaga tagctttacc acatgatttt
    24961 agcattaatc agccctatac ggttaatggc gaagctcaaa gtgcctataa gctaggtggt
    25021 gtaggctggt accggaagta ttttgccctt gatccaaagc tggctgacca taaggtctat
    25081 gtgacctttg atggggctta tatggaaacg caggtatacc ttaatgggca tttgatagga
    25141 gagcatgtca atggctatca ggcctttagc tatgatctct cagcctttgt aatccctggg
    25201 caagagaatc tattagcggt tcgggttgaa catctggtgc ctagctcgcg ttggtattct
    25261 ggaagtgggc tttatcggga ggcttttttg accgttcttc cgaaggttca tcttgataag
    25321 gatcggcttc gtttatcctt atcccaggca gcgcttgagg ctgatagcca agcgcttgag
    25381 atagagcttg gactcagcca acaggtcccc ttgagtggct atcagcttag ccttagtctg
    25441 tttgagcagc tggcagatat ccagcagaga cagacagtat atgagagtaa accggtagcc
    25501 ttggacctct tggaggagtc aggtaggctg gtgatgacca ttcctcttag gcatatcaaa
    25561 ctgtggtcgc cagctcagcc ccagctctat cagcttgata tgcttcttta ccataaggga
    25621 gcagtgcttg atcggctgac acttgaaaca ggctttcgac agctgcattt tgatgctgag
    25681 tgtggtttct ttttgaatgg caaagccttt aagctgcaag gggtctgtct tcatcatgat
    25741 cagggtagcc tgggggcatg tgcttatgag gaagctatag ctaggcagct tgttttgcta
    25801 aaggaaatgg gagcaaatac ggttcgtgtc acgcacaacc ctagtgccag aaggcttaag
    25861 gatctggcta acaggcttgg gttatttctc attgaggaag cctttgatac ctggacttat
    25921 gctaaaaacg gtaatagcca tgatttttca agccattttc acaagacagt gggacaccaa
    25981 aatgcagcca ggctaaaggg agtcactaca gcagaaacca cctgggcgca atatagcata
    26041 caggccatgg ttctctcagg tcttcatgat ccatctgtct tgatgtggtc aatcggcaat
    26101 gaattgttag aaggcttctc agctgatgtg agccactacc cttatgttgc taaggagcta
    26161 tgccagtgga tcactgagct ggatcagtca agacctatta cccttgggga taataagctc
    26221 aaggacaagc attttcattg ggcgcaggaa acaaaagcgt tggcagagca ggtcaatcag
    26281 ctccagtccg tgcaaggagt gattggactt aactatgcta aggccagaga ttatgatcga
    26341 ttgcataggg acaacccgac ttggctgctt tatggctcag agacagcctc tgctattaat
    26401 agtagagggg tctatcatct caagggagga gctagtcagg atcatgagct aacctcctat
    26461 gaccagtcaa cggttgactg gggatcctta gctagtgagg cttggtatga tacaatcaca
    26521 agggattttg ttgcaggtga gtgtgtttgg acgggctttg attatctagg ggagcctact
    26581 ccttggaaca agattgactc aggcgcagct gatcagtggc cgtcgcccaa gcaatcctac
    26641 tttggtattt tagatactgc tggatttgct aaggatagct attatttcta ccaaagccaa
    26701 tggtcaaaag acaaaacgac acttcatatc ctgcccagct ggcaggaaaa agaccttcag
    26761 ctagatgatc agggcatggt ggaggttgtg gtttatagta atgctgctag tgtgagaata
    26821 ctttttgatg atggtcatgg gggccagatt gattatggca tcaagaccct gacaaggcat
    26881 gaaacaccag caggccattg ctaccagcta tatgagggtg acgatgcagc agaattacct
    26941 catcaaaacc tttacctgac atggaagctt ccttatcgct caggcagctt gagagctatt
    27001 gcttatgacg acaagggaca ggtgctcaca cagaccagcg gtcgttcctg tgtgagcagc
    27061 taccagcagc ctgctcagct ttcctggtcc tgctttgagc ctcctaaact gcttgcagag
    27121 cctgcgctac tttatcttga attgtctttg ttagatgcta atgagacctt ggtgctcagt
    27181 gctaatcctg tgattaagct tgaggttgag ggtcctggag cctgccttgc tctggataat
    27241 ggcgatcctc gtgaccatag gccctatact gccttgtcac gccgagcata tggtggcaag
    27301 ctattagcca ttattgctct tgatggtcgt gcgggtcagc ttagaataac agctagagcc
    27361 gcaggattcg tggaagccag ctatcagttg acggtttctg aagcagccgt taatgagaag
    27421 cttttagcct atcagcttga taaatacagc tttatcacta atgagacaaa taagcctagc
    27481 aagccctatg caaggtcaag aggatcagct gttgatagct taatgcctaa tcctgatagc
    27541 tgcttaaagc ggcaaggcca ttatctgcct gataattctg taatggtttt tagctataca
    27601 acagcattat caaggccact gacctttcag ccactgatca aaaggctgct aaagggcaat
    27661 gatatcattc taccagactg gctgcagcct agggcagctg ctggccagtt atttaccaag
    27721 gcttttccta ttgattggca gctaacagag gcagtttttt ctgaggagtc aagggttagt
    27781 gggcagaccc tttgttttgg agaggctttg gagcttgaag ctatccttaa gtcagataca
    27841 aaaggattaa ggatcaatca agagcttagc ttagttgcta aaaagaagcg gctgtttcag
    27901 agtgataccc agcttagcta ccgctatcaa tacgatacca tacaggccat tggtgccatt
    27961 agcctgacag gactaaagaa gcccttaagc tcgcttaggc ttgttttgga ctatcgcagc
    28021 agcaccaatg cgccatcaaa acagctgatc ctatcgcttg atcagataga acagccctgt
    28081 cactacatca tgctggaaga agtagttgat gtgctaagcc tggacctaac attagagcag
    28141 ccgatcagac aggcttttga cttagctagg cttcagctag gcctttggag catggttgag
    28201 gaggcttagg cttcaagctt atcggctcat actgtcaata ggattgagct gagacagtct
    28261 ttgaaaaata aggtataatg acagtaaatg cctagcaagc tttgctaggt tagcaaaaaa
    28321 taagcatcgc ctgatatgat gtaaaggagg aggtatttga tgctagagcg tttatcaggt
    28381 cagacacgat taacagcttt gctggcagca ccggcacgtc acagcctatc accgaaaatg
    28441 cacaatgcag cttatgctaa gctggggctg gattatgcct acctagcctt tgaggttggt
    28501 aatgctgagc tagctgctgc tgttcagggc atgcgtgcct tgggtatttg cggtgcaaat
    28561 gtgtccatgc caaataagca ggccattgtc ccattgcttg atgagctatc accggctgca
    28621 gccttagctg gagctgttaa tacggttgtt aataaagatg gcagaggtca tcttgttggt
    28681 catatcaccg atggcacagg tgctattcga gccttagcag aagaaggggt ctcgataaag
    28741 gatcagatca ttacgattgc cggtgcaggc ggtgcaggca cagccattgc tgttcaactg
    28801 ggacttgatg gcgccaagga gattcgacta tttaatcgga aaacagctac ctttaagcag
    28861 gccaagcagc tggttgctag aattaatacc caaacctcag ccctggcaag ccttcaggat
    28921 ttagcggatg atcgagcctt taggcggtct atttcagagt ctagcattta tattgacgcg
    28981 actggtgtag gcatgaagcc ttttgaggag catcgcctga ttactgatcc agctcttatt
    29041 cgcccagatc ttgtggtttt tgaccttgtt tatcacccgg cagaaacaaa gctcttagcc
    29101 tttgcgcgtg agcatggggc taaaaaagtg atgaatggcc taggcatgct cctttaccaa
    29161 ggagcagaag cctttaagct gatgacaggt gaagacatgc cggtagccta tatccgagag
    29221 cttttatgtc agaacaagga atgaacgcct gctgctcacg ccggtatagg aaaaagaaaa
    29281 aaaggttaat tgctcagctc tttgattggt cttgaggttt gtcggcattt tatttataat
    29341 aaaaagcacc aaaagcaaag gagcagccta tgatattgac acaatttgac cctgactacc
    29401 aagctatcat taaccctaag gaccttgtag cagaaataga tgactttcct aaaacagtag
    29461 tcacctgctt tgcaagagca acctttaata gggtacttaa tgcactgcca catcgactga
    29521 tagccacaac aagcgttgct aatcttgata ttccaatata cgaattagat gttaaagggc
    29581 ataagcttgg ctttttcaat tcctacgttg gagcagctgg ctgcgttggg gttttagagg
    29641 atatcattgc tatgggaatg aagcagctct tggtttttgg gacctgtgga gtcttagacg
    29701 ctactatcag tgaaaactct attattattc caactagtgc tattcgagac gaagggacca
    29761 gctaccacta tcagcctgct agtcatgaca ttgcagtgaa tcaagcttat ttaacaaggg
    29821 ctattgatgt tttagaacag cattcccaga cctataccct tggtaagacc tggacaacag
    29881 atggcattta tagagaaacc agagacaaga tgattcaacg aaagcaggaa ggggctattt
    29941 gtgttgacat ggaatgctct gcgattgctg ccctagcagc tttcagacag ctagagcatt
    30001 ttcagttttt ttattccgct gataatctag atgctgatga atgggacgca agaagcttag
    30061 ccaatgaagc agacctagaa gccaaggata acattgcctt tattgcctta gagttggcct
    30121 tacgattatt taaggataat taaaaaagca ccaagagcta tgaagtgcct ccaaaaggtt
    30181 agattaaggc tctaacgcct gggagatcag ttcagctcaa ggtgcttttt aggtgtcatg
    30241 cagacagctc acctctgcat gtcaatataa tgtttagagt agcctatgct tcttatacct
    30301 atgccttagc attcacctag ggacaaagca atgaagctta ggcctttcac cttactgtga
    30361 aaaaagtggt cttttctcat caaaagactc agtaaacaag aggctttgaa gcctttttgt
    30421 ttttcagaag cagcagtttt ttcactcgac taataagaca ggagaaaagc cttctcaggc
    30481 gatatctagc aggcttctta gccaatccag caggcgactg tcatgcttag caataggaaa
    30541 gcttacatag ccttttgtcg ttggcaaaat gaggacaata tgctgaccag aatttttctt
    30601 atctgttttt aaaacagtca tcaaggcttc ggctgtcatt gacttagcct caagtgtggt
    30661 aggtagctga taagcctcaa aggcagcctg taatgcctct aaatcctgtt ggctcaatag
    30721 ctgctgctgg acggccagct tggcctcaaa gaccatgcca atcgcaatag cctcaccatg
    30781 cctgtaaagc tcgtgatggc ataaggcttc aatcgcatgc cctagcgtat gcccgaaatt
    30841 taaggacatg cggagattgc cttcaaattc atccttttca accactcttt ttttatggca
    30901 aatcgcttga aaaatcattt gcctgagctg ctcttgattg cggtccttgg ggaaggctag
    30961 gagctgttga aagagcttgc gatcatgaat aaaaccaatt ttaatcattt cgctgatgcc
    31021 gcaggcaaat tctctttcag aaagcgtgtc taaaaacttg gctgacacga taatctggtt
    31081 tggagggtag atactgccta tcatattggt caagccctta aagtgaaccc caaccttacc
    31141 accaatgctg ctgtctacct gactaagtaa ggttgttgga atctgaacgt aggaaatccc
    31201 gcggtaaaag gttgccgcaa caaatccccc aagatctcca atcacccctc ctccaacagt
    31261 aacaatgacg tcctttttag aaaaattagc cctaatcagt cgatcgtaaa tccgactaac
    31321 ctcctctaga gacttagatt gcccccctgg agcagcaata tgaaggtaac tatcgtaatc
    31381 ctgttgaaaa cgtctaaata aaggctggta taaatcaaat accgtttgat cagtgataaa
    31441 taatagcttg acgtctcctt tttcagcaag aaattgattc agcggctgaa aaatatcgtc
    31501 tgtaaagata atcggatagt cattgatacg agacttaacc tgaagtgttt gtgtcatgcg
    31561 tctttctctc ctaagcacca ttagttcaaa tgactggacc tgtggctgct gttagttagc
    31621 tttcccaaag ctcttttcca agctgctcta gctgttgata atcaatctgc tgcgcggcat
    31681 ctgacaaggc aagatcaggt gtagggtgca cctccatcat aataccattg gcaccgatag
    31741 ccttagcggc cttagccgca ggcaatagta aatctcttct tcctgttgag tgagagacat
    31801 caacaatgat tggcagcttc accttttgct gaataatagg gactgccatg atgtctagca
    31861 tatttctagt ttccacatca tagccacgaa ccccacgctc gcataaaata atattttgct
    31921 tgccattttc ttgtaaataa gataaagcac ccaaatattc ctcaatggtt gccattagtc
    31981 ctcgtttaaa caagataggc ttgtcaatct ttgacaatac ctttaacagt tcaaaatttt
    32041 gcatatttcg agcgccaatc tgaataatat ctaaatagtc ataggcttcc tctagctgcc
    32101 tttcagacat aatctcacta acagccttca gcgaaaattc ctggcaaacc tcatgtagat
    32161 aggtaacccc tgtcagccct aagccctgaa aggagttaga agaggttcta ggcttatagg
    32221 ctccccctcg aaaatacctg tagcctaaag ccttggcact tgctgctgcc tgtctgattt
    32281 gctgataaga ttcaatggca cagggaccaa caataaagtt actcttttga cagcccttgt
    32341 ttaaaaaatc agctattata tcgtttccca tttatactct ttcctaatat gatattgaga
    32401 gaatgattcc ccaaaggtaa gatgacagct ctgtcttaga taatactgtg aataaggcat
    32461 gacagaacta ttcatagctt gggaaatcat accataatca agcttaaatt tcaagctaat
    32521 aaagagagtg accagctcgt tgacaaagga gaagcttttg agaatcctag ccctctaagg
    32581 tagagatttt atggctatta gagctgttga gaatgcttat tagctggaat aggcaagcat
    32641 ggtggggaag tgctgatgat tgagtatcat gatgaggcta gttatagctt ttattgtggg
    32701 agagtttagc ttttcaaata caaaaagaaa aggtttacct atatcgtttt tttggtgtat
    32761 atataatata tagaaagcaa actattttag aaacagaggt aatggtagat gttaaggtat
    32821 ttaaaagcga ttttatatct attggctccc agattagctt tttcagtaac aggtgtatta
    32881 tttcctgatg tttttgataa tttattcttg gtttataata ttttaatgac acttgctttt
    32941 tggcttgcga tttattctgt tgacctccca gaaaaatagt tgcgggactt gtttagtagt
    33001 tggttaacaa agggtagatg atcagttaaa ggtgaagcgt ctgagctatg ttggccatta
    33061 tgcgtacagc tggcaaaatg cttttgatcc aatcggttaa acctcaagct attctctttg
    33121 ggataacaaa taccccatct gtctcagaca aagaatggca acgcctaaat aggattaaca
    33181 tctgcaagtg ctcttgggac tgccaatgct cttagtagca taggtgattt ttcagcgcta
    33241 gagacttttc agcagatgag aaatagtcgc aataaacgaa gacaaaaaga cttggcttga
    33301 gctcgtattt ggccttaaaa tagtagtcag tcgagcttaa aaaaaagtca ttgcagctta
    33361 tgaaggttat cgtatcctta tttcaactga gctaggtaag ctagggagtt tcctttaggt
    33421 gtaacgatag aagcgatcaa ataattactt catttaaaga taaggattgt aataagcata
    33481 gaaaagagca gttacttgac ataactactc aatgtaaaac cgtttcaggc ggtggctttt
    33541 gttattagat aaaaaataat cgtcatcatt cggccaaagt tagaacggtt atgttttatg
    33601 ctcatctttg aagatgttat agcacaagcc aatagggaga ctaaagctta aaaagagttt
    33661 gagtagcttc aaaggctgct agctttttgg cctcctccat tttgttagct gttgatgaat
    33721 cgcccatagg caccaccacc cactcagaac gagcagccac ctgtcttaat ttttttactc
    33781 taccactgta gcatgccaca agaaaaaatc agaacactaa tgacatttta aaaaaaaaaa
    33841 aaaagacttg cacaccaaaa caagttatag tatcatagaa aggtagccgc tatagttaaa
    33901 tggtataata aagcaatggt aatgcttcgt tccgagttcg attctcggtg gtggcatctg
    33961 agtactgtcc taagtcttat taggacggtt tttttattgc taggtgaacc aatagtagtc
    34021 atctgtgaat cattaccata gtggcttctg ttcgcccaag catagcaaag ctgctgtcag
    34081 aatgaaccca gccaacaatg tcaatagaag cagcaccaga caagccttta gtcacccatg
    34141 ctttaaagat tttacggctg taatgttagt aactgttacc tgttttgttc aagttgtctg
    34201 tgacatcaaa tcacttgatg ctaccagtac tgtcaataca ttagctgtca cttggcagtt
    34261 gttctgacta ctactaaaaa tagcagctat cagcgttgca atcaaaaaag aatgcgaatc
    34321 aagctctcct gatcagctta actttttgaa agagtttgta cgggtcaagc atcagcaagt
    34381 cagactgcct tatttgtttt tatcataagc ttctaagaaa atagcacaat aagccaggct
    34441 gtggtataat ggtaaggatt aagtcagaaa gaggggggca gacatgtctt atgagcaaga
    34501 ctttttgaga gattttgaag actgggtgaa ggctcaaatt caggtcaacc agctagctat
    34561 ggcaacgagc cggcaaattg caaaggaaga taatgatcaa agagccagag atgcctttat
    34621 tcgttatgag agtaagctag atgcttatga gtttttatta ggaaaatttg ataattataa
    34681 taaaggtaaa gcttttcatg aggtgccaga cagcctattt ggtagccgtc attattagag
    34741 gaagggataa gcagtaatca tggcaagacg atacaatcgt aaaaaacaat acaagctaca
    34801 gcttaagcgt caaggactgc tcaaggcagt aatcaatcaa gtggagcaga ctgtggaaaa
    34861 ggtggttgat aagactaaag aagcagtgca taccgcttca caaatggtaa cagcatcaaa
    34921 gacagagact gctgatctac aggataagca gagcattgct gaaaaagcag ctcagcctaa
    34981 agcagatgta gcttctagta gcttggctga cagttctgag gtttcaagtg aaaaagaggc
    35041 ctcaaaggct agcagtgaag tcttatcacg cgatgctttt gcagagttgg ctgaggtttc
    35101 agagcttcgg gcagatattg ttacggtgct ttttgaggct ggtattaggt cagctgctgc
    35161 ttttagccaa tggacagagg cagagctttt ggcgcttaag ggaattggac cagcgactat
    35221 cagcaagcta aaggaaaatg gtgtcaactt taaaaagtag tctgattttt attgcttaat
    35281 aagtataaat ttgttagaat gttagcaatc agaggtatct tgagtttgtc tgttacagag
    35341 agcggtggtg ttgagaaatc cgcacagatg tcaagttatg tagctgaggc ttacaatgga
    35401 aaaatgataa agcagcagat taagtgtaat ctgaaacagt ggtggtaccg cggattatta
    35461 gtgaattcgt ccctgtctag tcgattgact aggcggggtt attttttgga ggacttgcta
    35521 tgattgagat aatgggttct gttgagaata atagattacc agatgtcaaa actagtcgtt
    35581 tgctgctgcg gcagcgtact ttagctgatg ttgaagcgat ttttgcttat gctagccgac
    35641 ctgaggttag ttacccagca ggctttccac ctgtgaaaac ccttgaagaa gaggagcatt
    35701 acatcgcaaa cacgatgcct aagcgctggc ttttgcaaca gctgccggca ggctatggca
    35761 ttgccctaaa gggtgacaat aggattattg ggtctgttga ttttaacaac cgtcacgcag
    35821 atgatgtctt tgaaatgggc tatctgctcc accctgatta ttggcatcag gggattatga
    35881 ctgaggcagc gagtgccctg ctagaggttg cctttactct gcttaagctt cataaggttg
    35941 aaatcagctg ttacgattac aatatgggga gtcgtcggat cgcagaaaag ctagacttca
    36001 ctcttgaggc gaccattcgt gatcgcaagg acgctaaagg caatcgctgc gcagacttgc
    36061 gctatggact gttgaaaaga gaatgggaga ggcagtgtag ataaggagta gactctctaa
    36121 aatatgcgtt aatctgtcaa aagcatttca taagaagtcc tcaaactcaa agcgcttatg
    36181 actaccaaaa ctggttagcg cttcgccaac cagtgtcatc agtttctggt agtctgcctt
    36241 gagcagcaag tgttatgtta agtgaggtga gaagaggtaa gagagatcgg aaagaggttt
    36301 ggtatgaata ttatcttaat tggagcacag gcgtctggta agatgacaat tggacaggaa
    36361 ttagaaaaac tgactgacct gactttattt cataatcatg aatcgattga ttttgtgact
    36421 aagtttatac caatgtcatc ggaagctaga gaactaattg atgagctacg attgctattt
    36481 tttaaaacat ttgcaaaacg tcagcaatca attattttta ctgttgtcat tgattttaat
    36541 gcacctgaag atatagcgtt tttggaaaca ctacagagtg tgtttcatga tttcgacaga
    36601 gaggttttat tcgttgaatt agaaatagat ttaaaagaac gcttaaggcg aaataaaact
    36661 gaaaatcgac tttaccacaa accgataaag cgtcatttgg agtggtctga gaaagatatt
    36721 ttggatactg ctaaatttgc taactttaac cctgcaaagg taccagaaaa tcttaaatat
    36781 tattgtaaaa tcaataatac gagtctttct gctcaagaaa cagcgcagtt tatcgtccaa
    36841 aaaatgaaag agttagaagt aagctagaaa ggacaccata tgtcaaaaga actttcaccc
    36901 aaatacaatc cagctgaggt tgaggctggg cgttatcaag cttggctgga ccaagatgtt
    36961 ttcaagccat caggcgacaa gaaggctaag ccgtatgcta tcgtgattcc accgccaaac
    37021 gttacaggga agctgcacct tggtcatgct tgggacacga cccttcaaga tattattatt
    37081 cgtcaaaagc gcatgcaggg ctttgatact ctctggttgc ctggtatgga tcatgcaggt
    37141 atcgccactc aggctaaggt cgaggagcgc ttgcgcgagc aggggatttc ccgttacgat
    37201 ctcggtcgtg acaagttctt agacaaggtt tgggaatgga aggacgagta tgcagcaacc
    37261 atcaaggagc agtggggtaa gcttgggctt tcactagact atgcgcgaga tcgcttcact
    37321 cttgatgagg ggctctcaaa ggctgttcgc aaggtttttg ttgagcttta caagaaaggc
    37381 tggatttacc gcggtgagtt catcatcaac tgggactcgg cagctaggac agctctttca
    37441 gatatcgagg ttatccataa ggacgttgag ggtgccttct accacatgaa ctatatgcta
    37501 gaagatggtt cgcgcgccct tcaagtagca accacacgtc ctgaaaccat gtttggagat
    37561 gtggctgtcg ctgtcaatcc agaagatcct cgttacaagg acttgattgg tcaacatgtt
    37621 gttctgccaa tcgtgaataa gctgatccca atcgttggag acgagcatgc ggatccggca
    37681 ttcggaacag gggttgttaa aatcacacca gcccatgacc cgaacgactt tgaggttggt
    37741 gggcgtcata atctcccaca ggttaatgtc atgaatgatg atggtaccat gaatgagctt
    37801 gcaggtgaat ttgcaggtat ggatcgattt gaagctcgta aggctgttgt ggctaagcta
    37861 gaagaaatcg gtgcccttgt tgagattgaa aagcgtgttc attcagtagg tcattcagag
    37921 cgtacaggtg ttgtggttga gcctcgcttg tcaacacagt ggttcgtgaa gatggaccaa
    37981 ttggctaaaa atgctattgc caaccaagac acagatgaca aggttgactt ctacccacca
    38041 cgcttcaacg ataccttctt gcaatggatg gaaaatgtcc acgactgggt aatctctcgt
    38101 cagctttggt ggggacatca gatccctgca tggtacaacg aagcaggtga catgtatgtt
    38161 ggtgaggaag cgccagcagg tgatggctgg aagcaggacg aggatgtcct tgacacctgg
    38221 ttcagctctg cgctttggcc attttcaact atgggctggc ctgatgtaga ctcagaagat
    38281 ttccaacgtt acttcccaac gtcaacattg gtaacaggtt acgacatcat cttcttctgg
    38341 gtgtctcgta tgattttcca atcgcttgaa tttactgggc gtaagccttt ctctaacgtt
    38401 cttattcatg gtctgattcg tgacgaagag ggacgcaaga tgtctaagtc gcttggaaat
    38461 ggcattgatc caatggacgt tatcgaaaaa tatggtgcag atagcctacg ctggttccta
    38521 tcaaatggct cagcccctgg tcaggacgtg cgcttctcct atgaaaaaat ggatgcgtcc
    38581 tggaatttca ttaacaagat ttggaacatt tcacgttaca ttctcatgaa taatgagggc
    38641 ttgacacttg agcaagcaag tgcaaatgtt gagcaagttg cgtctggcgc tgctggaaac
    38701 gtgacagact gttggatcct ccacaatctc aatgaaacaa tcggtaaggt cacagagaac
    38761 tttgataagt ttgagttcgg tgtggcaggt catatcctct acaattttat ctgggaagaa
    38821 tttgccaact ggtatgtgga gctgaccaag gaggttctgt acagcgacaa cgaagacgag
    38881 aaggttatca ctcgctctgt tctcctctac acgctggata aaatcctgcg tctccttcac
    38941 ccaatcatgc cgtttgtgac ggaagaaatc tttggtcaat acgctgaagg ttctatcgtg
    39001 acagcggact atccaacggt tgatcctgct tttgaaaatg aagctgcgca caaaggcgtg
    39061 gaaagtttga aggacttgat tcgtacggtg cgaaatgcgc gtgcggaggt taatgtagca
    39121 ccaagtaaac caatcactat ccttgtcaaa acaagcgata gcgacctgga agccttcttc
    39181 aacagcaatg tcaactacat caaacgcttc acaaatccag agaggcttaa gattgcttca
    39241 agcattgtga ctcctgagtt ggccatgtcg gctgttatta caggtgcaga aatcttcctt
    39301 cccctagctg atctgctcaa tgtcacagaa gaattagctc gccttgaaaa agaattagct
    39361 aagtggcaaa aagagcttga cctggtcagt aaaaagctca gcaatgaacg cttcgttgct
    39421 aatgccaagc cagaagtcgt tcaaaaagaa cgcgacaaac aggctgatta ccaagctaaa
    39481 tacgatgcaa ccgtagagcg catcaaggaa atggagaagt tagtaaggta ggatagtgat
    39541 catctaagag ccaattggct ctttttttga tatactgtca aggagtaatc atcacaatta
    39601 tctatataag tcaaaggagt gtctcatgaa aaaaagagtc attggttggt taggtgtgct
    39661 ggtaataggg cttatgcttg gtctgatatg gtggaaatgg ttagtggcag atcggccact
    39721 aacccaagca ggtcaaggaa gtcatgacca cagcagcgac aaaggcctca gtgccgcata
    39781 aggaaaaaat ggaatcaaaa gagcctgaga catcacatca gccagaagcc tatcctgatc
    39841 ttgctagcta tcaggaattg gctgttcatg tgtcgattgc agaccaagtc atgaccatta
    39901 taggagatgg taaggttatt tttaagacca gcgtgtcaac aggagcaaag gaaagtccaa
    39961 caccgacagg gacctttgtc attgagcctg agcgaggaga ctttttcttc aatcaggcat
    40021 cagaagaggg agcttattat tgggtgtcct ttaaggacca tgggatttat ctgtttcaca
    40081 gcctaccaac agaccaatat ggcaatgaga ttccagagga ggcagagaga ctgggacagc
    40141 cagcctcaca tggctgtgtc cgcatgagca gagcagacgc caaatggttt tatgacaata
    40201 tcccagaagg catcagcgtc acaatagaat agccctaatc tccctcagaa tagcctgagc
    40261 agatagagga agagcctgtt aatattagca ggcttttaaa gctccttaaa aggctgcaaa
    40321 aaggaacgaa aaaagacctg aaacaggtcc attgatctaa gagaagacaa gtaactagcc
    40381 ttctagcaaa gtgttttaaa aatgcgttag tttagtagct tcgtgataat acaattaata
    40441 atatttattt aaaaaaactg taaatttcga ccactgttcc tggatttttt catttaaacg
    40501 tttatgccat gacttatgag cattctctct aatttctttt aggtatatat tttctactac
    40561 ccttttttga ctatgttctc gctctttttt tatttgctgt cttaaattct cttgtttttt
    40621 ctgttcttct aactcttttt gagctttctt ctgttcttgc tctattatgt cttgaggttt
    40681 agattctcct acaatccata tttctgaacc taagacaaaa ccatctgagg taatatgaac
    40741 tctaaattta tcaccattag aagcaatttt attatatgga acatatgttt cttctttgga
    40801 atttgttttt tgtgttctcg ctgattctaa agagaacaca atttttccat cccactttgc
    40861 aattggatag taccggttat ttgttaagtc accattgctt tttttttgga cttgtactaa
    40921 ttcagtttcc ttatcatctt cttcgacttt aaatattcta atcaaagatc ctggactagt
    40981 ttttactact atttctttgt cattattttt gattggttta acgccaaagt ctcgagcgtt
    41041 ttcccaatct cttctaaatc ctattacctt ttggtcacca atttgtggtg cttctgtata
    41101 atcatcataa ccataatagc cttgccctaa aactggagaa ttttcataat cactatttgc
    41161 acttacttcg ttgaaacata ttaaacttag taaaggtaaa ttaacgatta aactcatcac
    41221 taacttcttc ttcatttttt cttcctaacc tccattactt atgtttattt aataatagct
    41281 agggttagta taaatgagat gttgtgtaag gtaaagatgt ttattaaaag tgactaaaag
    41341 taaagaaata atcctaatag tagtttgggg atattttgat ttatacaaaa aataatgtca
    41401 ttgaacacgc tttatctaaa atagtctaac attctaacga aaataattcc aattattttc
    41461 atatactggc tagacatgct gtattagctt aatcaagaat tacagccgca gttttaaaga
    41521 cactcaggtt agtgtattat aaaaagctgg tgtgggttac aaaggatttc atatcactta
    41581 gattatgtca taattagtta agatgatgaa tccttatcta aaaacaaagc aaacttgtac
    41641 gtttgcgact ttcgtgatct ttaagcttac aaaagctgag taaattggta taatgatcat
    41701 taaaagagct catgctatga tgtagaccta taaaaggaga aaaccatgac atttgaagag
    41761 attttgccag gcttgaaggc caagaaaaaa tacgttcgta agggctgggg aggcgctgaa
    41821 aactatgttc agctgtttga tagcattgaa caaaatggtg tggcacttga ggtgacgcct
    41881 tactttttga ttaacgtgtc aggagctggc gagggctttt ccatgtgggc accgactccc
    41941 tgcgacgttc ttgctactga ctgggtagag gtctatgact aagcgggtgc tgatcactgg
    42001 tgtgtcatcg ggcataggac tggcacaggc gcgcctgttt ttgagaaatg gctttactgt
    42061 ttatggggtt gacaaggcaa aaaagcctga tttatcagga gattttcagt ttttacagtt
    42121 agatattaca ggtgatttag ctgagctttt tgaggctgtg cctagggttg atgtgttgtg
    42181 tcatactgcg ggcgttcttg atgcctataa gcccttgctt gataccacac aggctgattt
    42241 tgaggctctc tttcaggtca atttctttgc agctgtccgc atcacgcgtc actatttggc
    42301 acagatgctg acagctcaat caggtattat catcaatatg tgctctattg ctagcttcat
    42361 ggcaggtggc ggcggagctg cctatacctc cagcaagcat gctctggctg gttttaccag
    42421 acagctagcg cttgattatg ccaaggcagg cattcaggtt tttggcattg cccctggcgc
    42481 agtgcaaaca gcaatgacag ccacagactt tgagccaggt ggcttagccc agtgggtggc
    42541 tgatgagact cctatcggtc gttggcttag ggctgaagaa atagccgagc tgaccatgtt
    42601 tttggcatct ggaaaagcta gcgccatgca gggagaaatt gttaaaattg atggcggttg
    42661 gagcttaaag tgaaacagca catcgacata aggcctagca agatctggct tgtctgtaca
    42721 gagggtgaca gttgatagct gtatcaagca atcttgtcac aggctaagag ggagctgatg
    42781 aagttttttc catgaagcct agtgcctagt aggtttgctt aatacagcag gagcctacct
    42841 gtctagagga ttcgatcaat agaggtgata acatgactgc agaagaatta tggtctcaat
    42901 accagcaaat caatcctggt gttggtgatc tagctgaggc ctgggccttt ggagctgagc
    42961 ctgatttatt agcgcaatta gtgctagaag gcactaaaac agctacagcc tctgcctatg
    43021 actgatatga gcctgatcat gagccgcttt ccaaagaggg cagctatgac gtgattttgg
    43081 atagtaggga tcaggcgatc tgtattatcc agattactaa ggttagtctt gttcccttca
    43141 aggacgtgcc agcagagcat gcctataagg aaggagaggg tgataaaagc ttggaagaat
    43201 ggcggctgct tcatgaggcc tttttcagac cttattttga agaggtaggc ttacgcttta
    43261 ccgaggatag ccttattgtg ttagaggagt ttcagagggt ttaccctgaa gctgctaaaa
    43321 aggagaaata aatgaaatta gcccttgttg gtacaggcat gattgtcaaa gaggttttgc
    43381 ctgttttaaa ggagatcaaa agcatagact taatggcgat tgtttcaacg cctcgtagtc
    43441 ttgaaaccgc agaggcgctt gctgacgcct ttggcattca acaggccagc tgtcagctag
    43501 ccgaggtcct aaaaaatgaa gaggtggata cggtttatgt tgccacccca aatcatttgc
    43561 attttgaagt ggctaagcaa gcccttgagg ctggtaagca tgtcatttgt gaaaagccat
    43621 ttaccatgac agccaaggag cttgatgctt taagcagcat tgcaagagct aagcagctga
    43681 tattattaga agctattacc aaccaatatt tgccaaacac ccaatttatt aaggatcact
    43741 tgactgagtt aggagagatt aagcttgtgg agtgcaatta ttctcaatat tcctctcgtt
    43801 atgatgcctt taagcgtggg gagattgcac cagcctttga tcctaaaaag ggtggagggg
    43861 ccttgcgtga tttgaatatt tataatatcc atctgctcgt tggcttattt ggcaagcccc
    43921 aaacggttca gtacctagct aatatggagc ggcaggttga cacctctggt gttttgctga
    43981 tggattatga gcgatttaag gctgtttgta ttggggctaa ggattgcagt gcagagattg
    44041 tctctacgat tcaggggaat aaaggctttc tttctgtttt aggtgctcct aatgctgtac
    44101 cagagctttt actagccatt cgaggtgagc aagcaaggac cgtcaacttt aaccacccgt
    44161 ctcatcgcat gtacgatgaa tttattgcct tttcagatat tatctctaat aaggacatgg
    44221 aaagggcaga gcaggccttg gagcacagca aggcagtcat ggctgtttta gagcaggcag
    44281 cagcttcgct agaaagcgat agctaagagt agctagtggc tacaagctaa gtcatctttt
    44341 ttgctagctg tcttaagaag tgatgaccct tcttgttcta tcagatacag gtcttgttcc
    44401 tgatgactcg gagtctttca atcgcggagc ctaactgctt ttttcatagt gaggggtcta
    44461 atttgcagct tgctttgttt acgacatctt tgatacttag cgatgacagg cagctctagc
    44521 tagctgcttt aaaaaaggag tcaaggtagg taagggagtt tgtctgaagc taaggactat
    44581 tgcagcattc ttgttttttc tgcaaattaa ggccatttgt gctataatga gatgatctat
    44641 gtacaaacgg aggaagtcat tatgc
//
LOCUS       DARYVE010000012        43798 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYVE010000012 DARYVE010000000
VERSION     DARYVE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43798
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..784
                     /locus_tag="TVW25_000581"
     CDS             <1..784
                     /locus_tag="TVW25_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378242.1"
                     /translation="VKTPENKENCQCTKIYIEENGKDGYYLYIYEDTNKNDKYDKNKD
                     KLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQGPQGPRGDKGETGEKGQDGKPGKQGDR
                     GPAGPQGPRGDKGETGEKGDPGRNGKDGKPGEKGDPGQQGIPGPKGDPGKDGEKGERG
                     EQGPRGENPTPTPDPMPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPSTI
                     TSQPSGKALPKTNDTGSLITVLGTGLLSLLGLGFLTRRKRKQ"
     gene            1098..2189
                     /locus_tag="TVW25_000582"
     CDS             1098..2189
                     /locus_tag="TVW25_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1378243.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQSSGKGLPRTN
                     EAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(2322..3440)
                     /locus_tag="TVW25_000583"
     CDS             complement(2322..3440)
                     /locus_tag="TVW25_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378244.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(3437..4564)
                     /locus_tag="TVW25_000584"
     CDS             complement(3437..4564)
                     /locus_tag="TVW25_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378245.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(4573..5496)
                     /locus_tag="TVW25_000585"
     CDS             complement(4573..5496)
                     /locus_tag="TVW25_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378246.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(5519..6205)
                     /locus_tag="TVW25_000586"
     CDS             complement(5519..6205)
                     /locus_tag="TVW25_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1378247.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(6202..6873)
                     /locus_tag="TVW25_000587"
     CDS             complement(6202..6873)
                     /locus_tag="TVW25_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1378248.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(6848..8206)
                     /locus_tag="TVW25_000588"
     CDS             complement(6848..8206)
                     /locus_tag="TVW25_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1378249.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(8219..9283)
                     /locus_tag="TVW25_000589"
     CDS             complement(8219..9283)
                     /locus_tag="TVW25_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1378250.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(9280..10230)
                     /locus_tag="TVW25_000590"
     CDS             complement(9280..10230)
                     /locus_tag="TVW25_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1378251.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(10458..10622)
                     /locus_tag="TVW25_000591"
     CDS             complement(10458..10622)
                     /locus_tag="TVW25_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1378252.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            complement(11151..11408)
                     /locus_tag="TVW25_000592"
     CDS             complement(11151..11408)
                     /locus_tag="TVW25_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1378253.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(11945..13984)
                     /locus_tag="TVW25_000593"
     CDS             complement(11945..13984)
                     /locus_tag="TVW25_000593"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1378254.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(14350..15261)
                     /gene="glyQ"
                     /locus_tag="TVW25_000594"
     CDS             complement(14350..15261)
                     /gene="glyQ"
                     /locus_tag="TVW25_000594"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1378255.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(15627..16160)
                     /locus_tag="TVW25_000595"
     CDS             complement(15627..16160)
                     /locus_tag="TVW25_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1378256.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(16427..16651)
                     /locus_tag="TVW25_000596"
                     /pseudo
     CDS             complement(16427..16651)
                     /locus_tag="TVW25_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(16681..17520)
                     /locus_tag="TVW25_000597"
     CDS             complement(16681..17520)
                     /locus_tag="TVW25_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1378257.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(17607..18755)
                     /gene="nagA"
                     /locus_tag="TVW25_000598"
     CDS             complement(17607..18755)
                     /gene="nagA"
                     /locus_tag="TVW25_000598"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1378258.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(18872..20513)
                     /locus_tag="TVW25_000599"
                     /pseudo
     CDS             complement(18872..20513)
                     /locus_tag="TVW25_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            20704..21450
                     /locus_tag="TVW25_000600"
     CDS             20704..21450
                     /locus_tag="TVW25_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378259.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(22056..22898)
                     /locus_tag="TVW25_000601"
     CDS             complement(22056..22898)
                     /locus_tag="TVW25_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1378260.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            23030..23587
                     /locus_tag="TVW25_000602"
     CDS             23030..23587
                     /locus_tag="TVW25_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1378261.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(23998..24822)
                     /locus_tag="TVW25_000603"
     CDS             complement(23998..24822)
                     /locus_tag="TVW25_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1378262.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(24827..25441)
                     /locus_tag="TVW25_000604"
     CDS             complement(24827..25441)
                     /locus_tag="TVW25_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1378263.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(25602..26474)
                     /locus_tag="TVW25_000605"
     CDS             complement(25602..26474)
                     /locus_tag="TVW25_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1378264.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(26685..27170)
                     /locus_tag="TVW25_000606"
                     /pseudo
     CDS             complement(26685..27170)
                     /locus_tag="TVW25_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(27173..27439)
                     /locus_tag="TVW25_000607"
                     /pseudo
     CDS             complement(27173..27439)
                     /locus_tag="TVW25_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(27441..28373)
                     /locus_tag="TVW25_000608"
     CDS             complement(27441..28373)
                     /locus_tag="TVW25_000608"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1378265.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(28383..28898)
                     /gene="lacB"
                     /locus_tag="TVW25_000609"
     CDS             complement(28383..28898)
                     /gene="lacB"
                     /locus_tag="TVW25_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1378266.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(28914..29339)
                     /gene="lacA"
                     /locus_tag="TVW25_000610"
     CDS             complement(28914..29339)
                     /gene="lacA"
                     /locus_tag="TVW25_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1378267.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            29475..30257
                     /locus_tag="TVW25_000611"
     CDS             29475..30257
                     /locus_tag="TVW25_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1378268.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(30673..31224)
                     /locus_tag="TVW25_000612"
     CDS             complement(30673..31224)
                     /locus_tag="TVW25_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1378269.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(31237..32187)
                     /locus_tag="TVW25_000613"
     CDS             complement(31237..32187)
                     /locus_tag="TVW25_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1378270.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(33058..35289)
                     /locus_tag="TVW25_000614"
     CDS             complement(33058..35289)
                     /locus_tag="TVW25_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1378271.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(35289..35723)
                     /locus_tag="TVW25_000615"
     CDS             complement(35289..35723)
                     /locus_tag="TVW25_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1378272.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            35953..36990
                     /locus_tag="TVW25_000616"
     CDS             35953..36990
                     /locus_tag="TVW25_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1378273.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(37062..37412)
                     /gene="rbfA"
                     /locus_tag="TVW25_000617"
     CDS             complement(37062..37412)
                     /gene="rbfA"
                     /locus_tag="TVW25_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1378274.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(37602..40472)
                     /gene="infB"
                     /locus_tag="TVW25_000618"
     CDS             complement(37602..40472)
                     /gene="infB"
                     /locus_tag="TVW25_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1378275.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(40492..40794)
                     /locus_tag="TVW25_000619"
     CDS             complement(40492..40794)
                     /locus_tag="TVW25_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1378276.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(40787..41083)
                     /locus_tag="TVW25_000620"
     CDS             complement(40787..41083)
                     /locus_tag="TVW25_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1378277.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(41099..42253)
                     /gene="nusA"
                     /locus_tag="TVW25_000621"
     CDS             complement(41099..42253)
                     /gene="nusA"
                     /locus_tag="TVW25_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1378278.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(42363..42845)
                     /gene="rimP"
                     /locus_tag="TVW25_000622"
     CDS             complement(42363..42845)
                     /gene="rimP"
                     /locus_tag="TVW25_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1378279.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
BASE COUNT        12876 a        10357 c         8375 g        12190 t
ORIGIN      
        1 agttaaaact ccagaaaaca aagagaactg tcaatgtact aaaatttata tagaagaaaa
       61 tggaaaagat ggttattatc tttacatcta tgaggatacg aataaaaacg ataaatatga
      121 caaaaacaaa gataaactac tacagaaaaa atacataaaa aatgggaaag acggcaagcc
      181 tggcctaaat ggtcaacgtg ggcctcaggg cgaacctggg aaacaaggac cacaaggtcc
      241 tagaggtgat aaaggggaaa ccggagaaaa aggacaagat ggtaaaccgg gcaaacaagg
      301 tgatcgtggt ccggctggac ctcaggggcc tagaggtgac aaaggggaaa ctggagaaaa
      361 aggagaccct ggacgtaatg gtaaagacgg taaaccaggt gaaaaagggg atcctgggca
      421 acaaggcatt cctgggccta agggtgatcc tggaaaagat ggagaaaaag gtgaacgtgg
      481 ggagcaagga cctcgtggag aaaatcccac tcctacccca gatccaatgc cacaaccaat
      541 gcctgaccct gcacctaaac cagaatccaa gccagaacct aagccgatac ctcaaccaga
      601 ggttaagcct cagccagaga caaaacctca acaaccaaac aagccatcaa ccattactag
      661 ccaacctagc ggcaaagcac taccaaaaac aaacgacaca ggcagcttga taacagtatt
      721 gggaacaggc ttgctctctc ttcttggact gggcttctta actagacgca aaagaaaaca
      781 ataattaaag cactatctat agctttttaa tcattggcta tcaaacaaat cacaaaaaag
      841 cttatcgttt tactcctaac gataagcttt ttcgtattct ctattacttg gtcccaatac
      901 tatttttcca gctttaggct ggttttgtta atccaaaata atatcagaca atttccgttt
      961 taattaaaaa aaaaaaaaac gaaactgcgg aagctaatta tcagaaaatg attcacagct
     1021 tagagtcacc atgttaagct attctacgga gaagaaaggt ttgggaatga ctatttctaa
     1081 actcaaagga gagaaacatg agaaaaacaa tgaagaagat gctagcagcc tcgacagtct
     1141 gcatcatcat gtcgggcagc tttatcggag gcgcggcaag agtactggca gagcagtact
     1201 atggctatga tgatggaaca aaagacggtg gagactggcc agtattttta tatgtaacac
     1261 caacaaatca ccccgaaaga aaaaccgata aagagcactg tgtctattgc tttaacaggt
     1321 taaatagttc acctgagctc tgggaatctc aatttaaaga tccaagtaag ctaggtataa
     1381 aactccctat ctatgaaaag aaagaaggag atgaaagcct tttaagagct aaatctcaga
     1441 agcccagtga taacttaact tcaaaattag ttactgttct ttcaaatggc tatcctaata
     1501 agacattagg taatttaagt gaagatcaaa gtcgccgatt aacacagcta gctatttggc
     1561 actttactga tggatacgct acaaatcatt tcaaagatgg ttatcatcta aacaaagatg
     1621 aagattcaga attaaaaaag ttaattgaaa ctgctgaaaa aaacttccaa actacagcac
     1681 atacctatag cttaaatctt tatgtaactt catcatataa ttatagtaca ggtaaatttt
     1741 atcaacatct tcttggttcc actttaacac caaaacttcc gaacccaaat ccaggaccta
     1801 aaccaccagg tgggaacaat ccacatcatt taccaggtga aaatggtcaa actaaatatc
     1861 cagaaggaga aagcggtgag gcaggagctc ctaaaaagcc cgagcctaaa ccagagccta
     1921 agccggaacc aatgcctaag ccagagccta agccacaacc tgagcctatg ccagaaccta
     1981 agcctaaacc ggaacctcag cctaaaccag cgcctcaacc agaggttaag cctcaaaaac
     2041 caaccaagcc atcaaacact actagccagt ctagcggcaa gggactacca agaacaaatg
     2101 aagcaggcag tctaatgaca ggacttggaa caggcttact ctctcttctc ggattaggct
     2161 tcctaacaag acgcaaaaga aaagactaag acactaaaag attatctata gtcgtttagt
     2221 tgatcagtat ctagtctaat acaacacaaa agccttatcg cgccataaat ggaacgataa
     2281 ggctttttaa gcttggttca aaaagggtaa gacaacttag tctagcgatg taaaggcttc
     2341 atcagcacgc ttgctagtac cattaaggtc atggctgcta caaacaaggc caagaaataa
     2401 ggccaagcct cacctagatt accgccattt tggaaagtgc tgatgatggt taacacccaa
     2461 tgttgtggga gtagctttcc aatcgcctgc atataaggcg gcgtaatact aagcggccac
     2521 aaacaacccg ccagcataga ggttggcatc acaatcagat tagccaattg actgctttgt
     2581 tgcgcatttt tagaaaccgc accaatcatt aagccaaagc ctatagctaa caaactataa
     2641 agaaagaaag tcaacaaaac aatggctgtt ggaatgtaaa agctgacatt tgctaccctg
     2701 agtaatccca gcataatcac tatttgtatc gcaaaggcaa caataccaac acagacatag
     2761 ctcagcatgt attgaaggct tgatagcctt gataagacta agcgattgta gatttgactg
     2821 gacttatcaa gcaagatacc accgtacaag acactggtgc tgcctagcat taggatcaat
     2881 aaaaagccag ttgttgtcga ggaaacagac ttactttggg aacgatcagc tagggtgatt
     2941 tctttgacct tgtaggatag cttcgtgtta tgagctgaaa tcttcttgaa aacctcttga
     3001 ttgcctgctg ccgcatcacc aatgatattg taattctcca agagataatt agcctgcgcc
     3061 ttaaaccatt ctgttatttg actatcagca atcgaacgta gagcgatctt ttgagtgtct
     3121 ccttttagaa ccttctcacc aaagcccggc tcaatggtca gcacagcctc cagtgtcttg
     3181 gcctttaggt attgatcaat agccttttcc tctagcctag tatatatctg atatttttta
     3241 ttgtgcttta attgcgacac aaactgcttg gaaacctgac tcttatcctt atctaagatc
     3301 ccaatcttag cttgacttcc ccctgtaaag ctcaaggaca aggccagcat tgttgttagc
     3361 ataggcaaca ggataaaggt gatatagctt gtttttttac gtctaatttt gataaataag
     3421 gctttaataa aaggaatcat gctgccacct gctttctcat tctgaccaaa gcaaagagga
     3481 taaaggctgt tcctatacca agattaacca ttaaggtaac cggtatggga ttggactgcc
     3541 caccaaaaat aagataaaac aaactatcat tgacccattt tatcggggaa atattagaca
     3601 gctgattaat caaggcgcta tttaaggttg acaaaggaat atagcttcct cccaaaaagg
     3661 caaagacagg aatgactgca ttagacgcta ccgtcaaaaa ggattgattt ctaataccag
     3721 tcgcaagccc gataccgatg gcaacagaca aataaactag cgaggccgtc acaccgataa
     3781 tctgccagtc attagtcccc caattaacac gtaacacaaa tcgggtaaag acataaagaa
     3841 tggttagctg gactgctgtt gctagcatac caccaattaa ttttccaagc aaaatagcac
     3901 tatttgagac ccctgtcaaa taaatgcggc tagccacccc ttgctgacga tctgatagca
     3961 ccagattcat cgctgacata atgctataaa aggtaatcat ggtaaacatg gaaatagcat
     4021 agtaatccgc tgagctcatg cctttactgg tttgcacaga gctagaggcg atatagtcta
     4081 tttttctttt cttgatgttg ctaatggctt ctggataaag gttagcaatc gaatcatagg
     4141 tcttggcatt atccacatag atattgacaa gcatattaat caaatcagca ttctgttggt
     4201 taatgctgtt ggtggtcacc tcaatgtttt ggtcgctctt aacctctaga gctgccgtca
     4261 aggcgccctc gctgaccttt tgcttagcct tagcgatatc cttggtttct ttagcttcta
     4321 aatgaagctc tttatttaac agctttaaaa acgtgataaa gttcttttga tactctgttt
     4381 ccttgccctc aagctgataa cgaaccgtca atttaggaac agtagctgct gtattaaagc
     4441 tggacttaaa agcaaagctt aaaatcagaa tcatcaagat aggaaaaacc accatcatca
     4501 acaaagcagt ccgatcccta aaaatctgta agctttcttt tttgattaaa tgaaataaga
     4561 tcataacaac ccctaatctc ttagcttctt accagtcaaa tgcaggaaga tttcttctaa
     4621 attcaaatgc ttatgcctaa tctcactaaa agcaatatga gcatctgtca gctgacgaac
     4681 aaccgagcca atgtcttcat gttcaatcag gagaactgct tcaagctcgt tatccatcag
     4741 tctccaattg ggcttattag agagatcgat tgcttggtca gctgcgactg tcaccatgat
     4801 ttgctttgtg aaatcagact catagcgtct ttctagctcg gcctgactgc cctcttcaat
     4861 cacctgacca tgatccataa tgtaaatgta atcacataag gcctcaacct cttccatgta
     4921 gtgggtcgtg taaataacag tagctccttg ctcatttaac aagcgaatag actctaaaat
     4981 atgattacga gactgtgggt caatccctac cgtcggctca tcaaagatga ttagcttagg
     5041 agaatgcacc aaagcacagg caatgtttaa ccgtcttttc atacctcctg aaaactggct
     5101 tggaaactgg cttgcctgtg attttaaccc tacgaactcc aagcttttta aaacctgctc
     5161 cttgagctca cttcccttta agccatagag agagccgaaa agctcaacat tctcataggc
     5221 tgttaaatca ggataaacag caatatcctg agggacatag ccaatcttgg aactaatttt
     5281 tcgaatagat ttataagatt gctgtaaaac agtcacttcg ccagcattca aagggattaa
     5341 ccctaaaata gcattgatta aggttgactt accagcgcca ttaggcccta aaaggccgta
     5401 gattctccct tcctcaattg tcagtgagac atgatctatt gcctttttgc cgcctcgata
     5461 gaccttgaca acatctttta actctacaaa actcatatat tattccttct ttccaactct
     5521 aacgctgctc tttaaaacta attaacagat aagttaaggt caataaaagc gaaccaatca
     5581 accaaccata taataaggct gctgtcacac accagacacc aatcacacta aagaggcata
     5641 gggctagtag ctgctgtagc cagcctgagt aacgacaggc cttgaccaag gcatagccca
     5701 aaaccacaag cgtaagacct gccactgaat cttttcctaa aaagagacat agacctaagt
     5761 aacaaaaagc atcaaccagt gtgacaagac ttaacaaaag aaagctagct gctgccctat
     5821 ctggtttaaa ggctagccaa gtcatttttc ctaagagcag gcgactgtcc tttttcagca
     5881 taagatcaaa aagcaagacc aaaaccaaca gggtcagctc taccaaggct atgctataca
     5941 atagcacata acaaatgatt tcccagccaa aggatacgcg acccaaaaag gtcagcaaac
     6001 catcaagagc taaagcatca gaaaataata gacaaacaag cactagacca agctggatta
     6061 gaccaagcaa tagatcaagc cattgctgat aggacattgc cctgatgtgc cttaaatgcc
     6121 atctgactaa gcgccgtctt ttatgacttg ttagaaaaag ggtcactagg attaaaaagg
     6181 atagcaatgc tagtattatg atcatcgtac caccttctta tgcattgatt gaagatgact
     6241 caagccttca acccataaat tgcctccaac atgaacaagc aacaccagcc ataagctctg
     6301 actaacataa taaatacttc cgtaaataag accagtcagt attttggcgt aaaaaatgga
     6361 tctgcccatc aggaaatggt ttagggcata gcacaggctg gtgatcaaca agacaagagc
     6421 aattggcaat cgccattgaa gccacaagat gttaaaccaa atcaaacgat aggtgatttc
     6481 ctcacagcag gccaaaacca agggatagcc tatctgtggc catttttgtg tcgttccgac
     6541 aaatgatagg actaagggaa gccactcttt tttttgccag cagcggctaa gatgtaaaaa
     6601 agcaacctca acaaagagca caacaaagct caagataaaa ccaatgatca aaagacgacc
     6661 atcactatga cctaagggcg ctttaatagg aggtgacagc aggtaaatcc ctgttaagac
     6721 tagggcataa taaaccagta cagctcttaa aaaacctatt agattaaagc tatagctatc
     6781 acgaccctgg ccaaaaatag cctgcattgc gatcgaagga caaaaggtag ccattaaaaa
     6841 gcataggtta aggcattggg tgtacaaagg catttgtcac acctccaaac tgtctcatgc
     6901 gtggatgatt agcaaatgga aaggcaggaa tgcacatctc aagaagctca ggagtgagga
     6961 cacgtgtcac gtaccagcct ttttctgagg cctcaggagg agtaatgtct aaaaagacag
     7021 cattaggact tactttttta gtgtaggcta gtagtgtctt taaatcctct tttttatctt
     7081 tcccagcatg gtttgtcagg tcactaagac gaacctctcc tgaaatcaag ggctcaaagg
     7141 ccttccattt aagctcctga tcctttggat gagcatagta aaagacgtta ctatctaggt
     7201 ctaaaaacaa gggagagtca ctctcagcat tttgtgttga cgttggatta taaaacaaat
     7261 tatagtaata gctatagcta atagctgaag cttccatgat tcctcttaac agggtatgct
     7321 taggatccaa gcccgcctga accccaaata agagataagg accttcattg gacttgtttt
     7381 taaggataat accaaaggta taaagcggat tatcttctcc aacagtcatg tcaataggga
     7441 taatctcata aagactgtcc ttaccaagtc tagcctcttc caaaagagct agaatttccg
     7501 gatcatcaat aatcactctg ggacaaggct ttttagtatg ccagctaagc atcatagagt
     7561 cgatttgaat atactcaatc aagctattac acatggctgc ttccagcgtt gtatgagagg
     7621 ctgtccccgt tgaaaagcct ggaatgatgt gcttttcgcc tacagcctga ttggtcttat
     7681 agccaacgca aagcatttgg gcaggcacat acatctcctt atcttcaaaa aacatcggac
     7741 acttaaccca gcccaagaca tcgtcttgcg tcaccatttt atcacacatg atcatgtgca
     7801 aatcatggca acggtcaatt tgttcctgcg taaaaacctg caaatactct aagggcatga
     7861 caggatccgt ctggctcaat tccttataag aagcataaac aatccggtct gataataatt
     7921 ccccagcaat aacagtggca taacgctcaa tgctttcacc taagtatttg atcaaggctt
     7981 cctcataatg actgccataa ccaatgatat gatagctcac ctgactcagc tcaccaataa
     8041 attgcttgtg gtagtcaggc atctgtcctg tcacactctt taagtaaaca tcatgaggat
     8101 ggttacaaat aggaacctga gattgattta agataccagt tcggttacca ctaaggccct
     8161 ttagcttatc aagaatatgg ttgaacgaag ggtaataatg tagcatcctt agacctcctt
     8221 atgactcttc ttgaaggagt tttttaacaa tctcacgtgt tgaaatctgt tgatcctcat
     8281 accttaattt tgtcagagcc ccttgtgtct gagaattaga cattttcaaa atatcctgca
     8341 cctgaatctc aagcgttggc aaatagacac ttaacaaacg cccttcaaat tttgagcttc
     8401 ctgtttgagc aataataaag gcctcactga caaccagatt cattaacaca tttaacaaag
     8461 gtacataaga ggagctaaca ggctgtgttg gcggcaactg ctgacttgca aagcgctgat
     8521 aaagcgtgtg atcctgtaaa cgtgccagca cccttctctc caagctatca aaatcagcac
     8581 tatgaggagg atttaaggta caagcatgga taaacggccc atcaacaaag ccaagcacca
     8641 attgtttttt caaggccaca ctgatttcat taaggtgacg cagcatcata atattcaacc
     8701 ggccttgaca aataacaata ctctgatagt ctgcgagctt ctcagataag cacttcatgt
     8761 tgcgatggtg ctccagagca tctaagcgag aggtaacatc tgtttcttga atgagcattt
     8821 ttagctcatc gctagccacc tgaaggttta agttcaggtg cttggccagc agctcagcag
     8881 attcattgac atagcttgaa tcactgataa ataagacagg tgcagtatcc ttagcctgtc
     8941 ctgattcagc tatgaaatga taattgcctg ttaagacctt catgatattt tcttcaagag
     9001 cataagcgtc ttcaagcatc aataggtcgt tataatacaa ggctgtgatg acctctgaca
     9061 attttgcaaa taagtcagac tctagtgttt tttcgtaggt atcagtatca ataactttcc
     9121 cgttaaacca atcggagatg atactgtagt aggcttcttt taaggcttgt ggctcttgtg
     9181 caatgtctaa aacagcttca ttaaaatccc ataggccttt tctaaagcaa aacgtatcgt
     9241 caaattgcac aatgcgaaca ttgctattta attgatattt cattgagact ccttatttcc
     9301 aataatcgtc atgtgaatca catgctgggt caagccatcc aagcctagct tttcttggag
     9361 gtattcctta ttgtaccctc caatatcaac acttccatat accaaagctg ttgagaccaa
     9421 ttgaacattt tgagcaatct ctccagcttc aataaaggca taagcagtag cttgatttcc
     9481 atatttacgt gtgtttttga tgtactgata aacatagata agaatgacat tgcagttttc
     9541 ggcagtgatc ggtccgtatt cggcaaaggc tctaatatcc tcctgatcac taagatgatg
     9601 acacctcagc gcgtgctgat aaggaaggta ttcataaaaa ccgtccttga gtgtttctac
     9661 gtttcttgca tagaaaaata aggtgatggg gtacagaccc ccaccagaag cacaatttct
     9721 taaggctact gtcttagtca tgccttcttt gatgattgcc tgagagctga caccacaagc
     9781 ataataaagc aaatcagcca aatcctgcaa aggcatctcc tcatctataa actgcctatg
     9841 acttctccgg ttggtgatac aggttgatag ggctgctgag accttcttag ctttaggaag
     9901 tgctatcgtg tttgccctat cctcaaaata gtcactattt gaaaaggtgg tcactgcaga
     9961 atccgtaaaa aactcagcca cactggtctt aaaccctagg taattgttat tagccttgta
    10021 attcatcaaa aaccgttggc taagattgtc tgtttcatca ggcatcaaat gctgtgccac
    10081 aagctgtttt gatgttttta ataccgtttg atgatgatag gttgataacg ataagtgatt
    10141 ggtattaaat tcaaataact gtcgtgcttc ttctcttgtt aggtcacttt ggttatccga
    10201 acgttgtttt tccttagaaa aaaatggcat aactgtcttc ctgtaatata ttaataaata
    10261 atagtaatta gcaggtaccg actagtacct gctaattact acaagacgtt gacatcaagc
    10321 tgattgtctt cgtctcttgt catgtaacac ccctatccaa caccagctaa caccatcaat
    10381 tacaaactgt aaccttagtc gctagcaaac taatgattgt gacctagcta ttaactatta
    10441 aatagaagta ttaaagttta cgcttttggc tcagctgcac cataattgtt gtttatggta
    10501 gtattgcccc atgaagctga gacgcagcaa caacaagaac agcaacagca gcaaccacca
    10561 ggagcaactt gagttgtttc tgctacacta gtagctaaaa tatttgaagc aaattgtaac
    10621 ataatgctta cctccttata tcgcctgatc ggtaaaacaa aacactgata agagttaaat
    10681 gagaatacct ctcaactgat agcaaaagca atcatgagca ggtatccagc aacacaaggc
    10741 tagctatttt gtatcgccct tgttaaagtg accattcaat tcttaccaac tatattatat
    10801 taaaattcaa gacatatgta aatactttct ttaatatttt cttacaaaaa tgtcattatt
    10861 tttccagaaa ggttagctta ttgagcttga caaagtctta agcctatctc tttaatggca
    10921 tttataaact atcagtcttt ttaatgaaac gcattaaaat aggtagagat attattatct
    10981 ctacctaaac tgtattgatg agacagatgg ctagtacctc acaattaacc atttctaaaa
    11041 ataatgactc ttttgtcgaa agacctaatg attaaagcta tttgtctttg tttatctttt
    11101 tctcattagt aacattaaat catggcaaaa tatttatatt catttaataa tcaagattcc
    11161 ggatcatcaa gtgaccgtcc atgcagacct ttttcgcgct gcacctgtct taatttctca
    11221 ggagtaacat cgtttccgtc ttcatcaaca atcttaatgc cttcaatgtg atggcgcact
    11281 gagcggcgat agccctcaat gtattcctca cgcagcttgg cctgctctac cttttcagga
    11341 ccagtcaagc caactgtttt tttctttttt gcaagctcgt taatacgagc gattttttta
    11401 ggatccataa atcacatata agggctgcac caaaagcagt gagcagctga tgaggcttga
    11461 tgatgggcta gacagcctct ttaggaccgt tactaggacc tttcaagtcc tttttcacca
    11521 gctgtgccag caagggctgc ctgcaaatgg ggctgcctct aatcctttct ctttcgtttg
    11581 tgacatagag tactgcactc tttttgtcta tatctaaggc tgtgccagca gctgcttagc
    11641 cttatgcttc tgccaagaag gctgtagcaa gcttcttgtg aaaagctaaa atccatgctc
    11701 actttactaa cagtgttcct gatgctttta ttgaccactg accagcacag ctattgctag
    11761 caaagctagc ccaagacgat atctcgtagt aagcaagagg actgatttga ctaagtatca
    11821 attgcttgat aagtcttgag tgcttaggga aggacttatc ccaaggcagg taatcagtca
    11881 cctatatcat ctagggaata cgaacagcta acacagggcg atgtgcttaa tcttacacag
    11941 cgaattattt agtatttaat cggtcaaagg ccgcaatggt ctctaccttt ttaaccagct
    12001 ctgctaacag cgctaaacgg ttacgtctaa tagcttcgtc ctctgtcatg accatcgtat
    12061 ggtcaaaaaa gtcatcaata actggactaa gggcaaagac ctgagctagc tgttctttgg
    12121 ctgatccaga tagcactagt gaatcaacag cctgtgccaa agccctttcg tagtcatttt
    12181 caaagaggct agcatcaatc agcacagcgt caactgcctt tttcgctaga ttaaagacgc
    12241 gagacagcga ctcgacagca ggcttgtagg tgtctagctg gcttgccgca gccagagcct
    12301 ccgctcttgc taacagttct ggtacaacaa agcttgagct agccagaact gcttcacgta
    12361 tatcctttgg aatggctgag cccatcattt tatccacacg tgcacaaata aagtccagca
    12421 cctcagcctt atgctgatag gtcaagctat caaatgacag ctcatatagg ctatcaatca
    12481 gcttatccat aggaatgctc cagccgaaat gctcaagaat tcggacgatc ccctgagttg
    12541 cacgacgtag ggcataaggg tcatttgagc ctgacggtat caaaccaaca gagaaaaagg
    12601 acagcagggt gtctagctta tcagcaagag caaggacagc accaaccttt gtttcaggca
    12661 gctctccttc tgccgaattt ggcaaataat gctcacgaat tgctgttgcg acagcagcag
    12721 cttcgccagt taaaagggcg tatttctccc ccataatgcc ctgcaactca tcaaattccc
    12781 caaccatacc agttagaagg tcaaatttat aaatctgggc agcacgagcg acagcacttt
    12841 tttctgcttc tgagagccca gcctggtcag caagaaaggc tgcaataacc ttggtccgct
    12901 ccatatgctc agccacagag cctatctttt catggaaggt cacatgagct agcttagcaa
    12961 ccaaatcttc aatagataac ttttgatcct cacgccagaa aaattctcca tcttcaagac
    13021 gagcaacaag caccttttca ttgcccttaa tcacattttg aagatgctta gcattaccgt
    13081 tacgaacaga aataaaattc ggcattagct tgccagcctg atcacgcacg acaaaataac
    13141 gctgatggtt cttcattgag gttactagaa cctcttctgg gatttccagg tacttgggat
    13201 caaaacttcc catgaaggca gttgggtatt ctactaggtt gagcacctca tttaagaggt
    13261 cctcatcaat atccacctga accttttgct ctgcttcgat ggctctgatt tgtgctatga
    13321 tcatctcttg acgctcctta gcagaggcaa tgacaaattg gctgcgcagg tcagcctcat
    13381 aggaatcagc acttgtaatg ctagtctctt ctccaaggaa gcgatgtccg cgactgatac
    13441 gtcccgaatg aatgtctaaa aagtcaagct ccaaaggctc atcatctaac agtacaatca
    13501 agctatgcac cggacgaata tagtcaaagc tattgttagc ccagtgcatg ctgactggga
    13561 aggtcaagga agcaagaacc tctggcaccg ctgctaagac gtccttagcc tgcttgcccg
    13621 cttcatgctt ggtgacataa acgtattcct cacctttgac ctctcggaat tcgatgtcat
    13681 caacagtcaa gccctttcca cgaacaaagc cctgagcggc ttttgaaaat tgaccatctg
    13741 cgtcaagagc aattttttta gagggtccct taaaatcctc tgtcagatca gtctgctgat
    13801 cagctaagcc cagcacacgc actgctaaac gacggggcgt tgaaaagcct tcgattgcgt
    13861 catagctaag ccgattggcc ttaagaaaat cagccatacg ttcaacaagc tgcttttcac
    13921 taggtgtgac aacgtaggca ggaagctctt caagaccaag ttctacaagt aaatcttttg
    13981 tcatcattaa aatcctatgg gcatcaaatc taaaagagaa gaccaaaccg atcctagcat
    14041 gccttgggca agcttggacg atcctttgtc tacaagattt gtcccatctt tctttccttt
    14101 cttcaagtta tggggtaggt ttaggagacc aaatcactag ctcctaatcc tgcaagcctg
    14161 ctaataagct gcctgttaga caagatcact tagcagaaag actgagctta acaggactag
    14221 tcatcaggcc tttaagtctc atcgctttta aaaagcacct accagatagg taagctgcta
    14281 gcagcaacta gagcttacaa gatcatacaa gctgcattga ctacaaggaa ctagtttaga
    14341 tccagctgct tagtcctctg ccagcaaggc tactcggcta gcatcatcca acaatgggaa
    14401 gccaagcttt ttacgctctg caacaaaggt tttagcaacg ctacgagcta aatgacgaat
    14461 ccgagcaata tagccagcac gctctgtcac agagactgca ccacgagcgt caagcaggtt
    14521 aaaggtatga gagcatttca agacatagtc ataggctggg tggacaagcc cttgtgctaa
    14581 agcacgctct gcttcttttt caaatatctc aaagttttca agcagcatgt cctgattgga
    14641 tacctcaaag gaatacttgg aatgctcata ttctggctga agaaaaatct cgccgtactt
    14701 aacaccaggt gcccattcga tatcatagac cgaatccacc tcttgaatgt atgaggccaa
    14761 gcgctctaag ccataggtga cctctgctgt cactggtgat gttgctaggc ctcccacctg
    14821 ctggaagtag gtaaattgtg taatctccat accatcaagc cagacctccc agccaagtcc
    14881 agctgagccg gttgaaggat tttcccagtt gtcctcaaca aatcgaatat catgctccaa
    14941 tggatcaatg ccaagtcttt caagagattg caggtaaagc tcctgaatat tacttggaga
    15001 aggcttcatc accacttgaa attgatggtg ctgatacaga cgattgggat tttcgccgta
    15061 tcggccgtca gcaggacgac gagatggctc cacataggca gcattccaag gctctggacc
    15121 aatagcgcga aggaaggtat aaggactcat ggttcccgct cctttttcat tgtcataggc
    15181 ttgcattagc atacaacctt gatcattcca atattgctgt agcgtcaaaa taatctcttg
    15241 aaaggtaagt ttgttactca tgatttcctc tttctatttt ttatgtcttg tcgcaggcgc
    15301 taaccaagag ctggctatgg cttgactgct ggttggctct taaacagctt ttcaaagaga
    15361 aaaaccgcgc ctatagccac ctacacctaa aggcataggg gcgtcaaaac gcggttccac
    15421 cctaatttat tacttcattt gatcttgttg ataaacagat gtcaagcaag ctacaaacac
    15481 ctgagcctac tctttagaga aagcgccaac cagcagtacc atcactcggc tctcaccagc
    15541 cccgagctcg ctttagatca gaaacctgct attttctttc ctattggtta gtttatcaca
    15601 aaatcctatg attgtctaat caactattat gattttggac gagttccgtt tggaataata
    15661 acctcagaca agagcctatt ttcttcacga atgcgcagat aaatcacaat aatatagcaa
    15721 gggaaaagca gcattgccgt aatctgagca tggcaaagca aagcaatacc aaccagctct
    15781 ggagcaatgt ttaaaaagta attggggtgc ttaacagtct taaagagcca atgatcgaca
    15841 tatttatggt cctttgccag catcagcttc actgtccaaa tatctcccaa gatccgagtt
    15901 acctcatata gcacagctat cgaaaaaatc atcagcagca agccaagaaa gctaatgcca
    15961 tcaaacttaa tctgcttgag caatgcctct gtcacagcaa agacataaat catgatatgc
    16021 agcagggtca aaaacttagt gttttgcgca ccaaattcct tgcccccatt agccaggata
    16081 gccttctcgt ttttgatcga tttttttaag aatactaaac gaatagcaaa catcaagagc
    16141 atcaataaca ggataatcaa agtaagactc ctttattcta gtttaatctg tttctttcac
    16201 gaaacactaa ttaagattat agctaagtta cacagccttg tcaaaccgtt ttcaaaaaaa
    16261 agatgtcttt ctttgatctc taaaaacaag aggtcgtcac acagcaccat caagagacct
    16321 catcaaagct ttaaggtcgt accaaatcac catcaaaaga cagctcctag actcagtcaa
    16381 ttcacgagca gcaagcagca cccaagaggc attttgcagg cctgacctac ttcgcctgtc
    16441 gtaaacacaa atcctcaata tggtaaatag cgtcacattg cgctgcaacc tcatcgctgt
    16501 gtgttgccat taagacaatc atatcctcag tctgacaagc tctgatggct tgtaagacct
    16561 cctgctcagc ctcaatatcc agggcgcctg ttggctcatc tgccaataac agctgcggtg
    16621 ttttgaccaa agcacgagca aggaccacta atgtagctca cttaatccct gcagctcttg
    16681 ctaaaagtcc ttggtatcag gatctgggat agctgacata cccggcaggc aacgaatgcg
    16741 ctctgaatcc tctggactaa tctcacaatc aaaaatagcc atattttcta ctatgcgttc
    16801 cttgtgcacc gacttaggta gaggaataaa gccctcagca atagaccaag caagggctag
    16861 ctgagccact gtcttgttgt actttttagc caatgcctgc atggtatcat cggcaaatat
    16921 ctctccttgt cctaatggac cccaggcctc tagcaaaatg tgatgcctgc ggcaataatc
    16981 aaccgtctct ttttgatagc agccaggcgc caagcgaatc tgattgactg ctggtgtaat
    17041 ggttgctgtc tgtttaagag cctccagatg gtgaaccata aagttgctga caccaatcga
    17101 gcgaaccaag cctgcttcaa cagcctcctc catataagac caagctgctg cattggctgc
    17161 ttgccagcaa tccctaagag ccttaggatt tggccaatga atcagataaa ggtctacata
    17221 ctctagtcca aggcgctcaa gagaggctgc taaggctgcc ttagcgccat catagctatg
    17281 agcatcattc cagagcttag tggtaataaa gagttcttca cgaggaacgc ccgaatcccg
    17341 aatggcctgt ccaacacttt tttcattgtg ataaatggca gctgtgtcaa tatgacgata
    17401 gcctgcctta atcgctgcta gggtggattg gtaggcctcc tcaccatcag cagccttaaa
    17461 ggtcccaaag ccaagcactg gaatagcaag accattagcc attgttactg ttttaatcat
    17521 atctaaaacc tcctttttca ttgtagcaca atgataagca aagcaaaaag aattgagctg
    17581 atcaccagcc caattccttt gctgtattaa gcctcaaagg ccttttgacc atttaggtag
    17641 gttgctacta attctaagtc cttatcaaga acaataaagt cagcagcatg acctgccttg
    17701 atttggccac agacatcttc aataccaacc gaagcagctg ggacgtaaga ggacatgtga
    17761 attgcttctg ctggacttgc aattccccag gcaacaacat ttttaatgcc gtcctttaat
    17821 tttaagatag agcctgctag attaccacta tccttcaagc gagctgtgcc attttccaca
    17881 ataaccggaa actctccaag catgtaatca ccatctggtg aaccgcctgc acgcatacag
    17941 tccgtaatca aagccacatg ctcatgaccc ttttgctgca tcaaaatatc gcaagcaaca
    18001 ggtgagacat gatgaccatc gcagatcagc tctgcaaccg ttccaggaat attataaaca
    18061 gccccaacca taccaggctc acgatgagtc aagccacgca tcccattgta ggcatgaacc
    18121 caaacactag ctcctgctgc tactgccttt ttagcctcag tataggtacc atttgagtga
    18181 cctaaagcta ctgtgacacc ctgcttggtc acctcagaga caaatgcttc tacgccatca
    18241 cgctcaggag ccaaagctat ttttttgatc aagcccttag ctgctttttg ccaagctgca
    18301 aattcgtcta agcgaggatt tttcatatat atcgggtttt gggctccctt gtattcctca
    18361 gtgaagtaag gcccttcaaa ataaatcccc tgaatctttg ctcctttgac ctgatcggca
    18421 acagaagcaa cggttgcaga cacctgctct agatgctcaa aggttgacgt tagggtagtc
    18481 ggtaagaagg aggtcactcc tgttgataag agaccctcac tgatggcatg gagaccttct
    18541 gctgaattat ccatcacatc agcaccagca tagccatgaa tatgagtatc tacaagtcct
    18601 ggtgctattt gatagcctgt ataatcaata acctctgcct gatcatcaac agtagccgtc
    18661 caataaccaa atgtgccatt atttagctcc aaatagcctg ctggctttac ctcgttgggg
    18721 taataaaagc aatctgcttt aatatagctt gtcatctttt ttcctccctt tttcgtttat
    18781 tatacgcctt aattcttatt ttgtaaatgg tatataccag tccttctgtt aaaaagaaaa
    18841 acctgaatac tatttcaagt tttccctttt attagagctg tcctgaaagt actttctcag
    18901 ctagatttag ggcgtggtca gtgatacgtg tgtaatgaga tataatgtca ataaaattaa
    18961 tccctgcctg tgctgtgcat tcgccacgat tgaggcgttc gatgtgtgtt ttacgcaatt
    19021 gacgctcttt ttgctcaatc gtcctatgac gctcaacaat agactgggct agagccttgt
    19081 cactatccac aatcgcccta atcgcatcta aagttaaaca gtgggtcagg tgatacattt
    19141 ctgttaattc accacgtgca gctgctgaaa agccaatctg ctttgctgta atcccctcaa
    19201 tgagagtcgc taacgactca gagtggtcac caattcgctc caaatcacga gacgaatcca
    19261 acagacctgc taaaacctca ttttcactag gactaagggc ttcattggaa atatcaacga
    19321 ggtaagtggt gagctcctca tcaatcgtat tgaccgcctt ctcatatcgc ctcacctttt
    19381 cgccaaactt gtcttctgct gtcataatgt agctataaga cgcctcaaaa gcctgaatag
    19441 cataggaagc cagatgtacc aattccttgt gggcatttcc caaggcaata gaaggagcct
    19501 gagtgattag taaacggtcc aaatacaagg cttcatattt gacgatttcg tcttcacctg
    19561 gaattaaggt ggtcacaagc tttgccagag tgttgataaa aggaagcagc aacagggtat
    19621 ttgtgatgtt aaaggtccca tgtgaaaagg caatggtcat ctcaggtgac agggccaaaa
    19681 cagactgaag ccatagcata aaggaggtaa atggcatcag taaaatcata aagatgaccg
    19741 tcccaataac attaaaaaga atatgagcag cagcaacacg cttagctgca atattagagc
    19801 caatagctgc caaaaccgct gtgatacagg taccaatgtt agagccaagc aaaataggaa
    19861 tcgcaccctg cagggtcaat aggccacccg aaaaaagccc ctgtaaaata ccaataatgg
    19921 ccgccgagga ttgaatcagc atggtcaatg ctgtcccgat aaaaacaccc tgaaagggct
    19981 tgtctccaag cgtcgctagg taatgctgaa aggctgagac tgattttaaa ggatccatcg
    20041 catcacccat gaggttgaga gaaaagaaaa ttcctcctac accaaaaatg atacgaccta
    20101 ggttattgag ttttttattt gacgtgaaaa agagacaggc tgctccaata aaaatcatgg
    20161 gcagggcgta atctcccagc ttaaaaccaa tcaaaaagga ggtcactgtt gttccaatgt
    20221 tggcccccat gacaatacca atcgcctgct gtagggttaa aaggcctgca gatactaggc
    20281 caactgtaat caccgtcaca cccgagctag actgaatcaa agcagacata gctattccaa
    20341 ccaagatacc aaagaagggg ttgcttgtgt acttgtcaat gtaataccta agcttatcac
    20401 ctgcggcctg ctgcaagtcg tctcccatgt atttgatact gaaaagaaaa agacctaagc
    20461 cctgtactgc cccccaaaaa atgaaacgca atgtcttgcc aatttaccga cacaatattg
    20521 tcctcactcg cttatttatt ctcttctatt ttaatgtatt tattcagtta tcacaagggt
    20581 tttttaatcc ttttaaatag tgctcattta gaacctattt tagagcccta gtcctctttt
    20641 cattttccta tattcagggt ataatagtgc tactcaagcg acaatgattt caaaggagat
    20701 accatgagaa aaccgacaaa agagacccac tacctcatca ttagcttgct tactattgcc
    20761 attgcaggag gggcctacct tatttttagt agcctctctc caaagccagc taccattacc
    20821 acccaatcta agggctatga gctgttaact aaggctcaag cattagtcaa ggaggccgaa
    20881 gacaacccaa ctaaagaagc tatcgcaaag gctcaaaaag caattaatca gctaaaaaag
    20941 acccagtcta aggaggaatt acaggctcga ctaacagcta tcagcttaaa gcacaatcaa
    21001 gaagacgttg ctatcaaggt cctaaaggca gccgaggaca atccaagccc tgaacttaag
    21061 gaggctgcac aaaaagccat tagtaagctc tctgatgagg ctaaaaaagc tgccttacag
    21121 gctagacttg acgctattgg actttcaaag cctagcactg cacagcctga gactgcaaca
    21181 ccagcagcag aaaaaaatat agcaccagct cctgcggctc cacaaataaa gcataccaca
    21241 ccgtcttctg ggggaacgac gccagcaccg aaccctaaac ctagtcctaa gccgaatcct
    21301 cagcctagtc ctagtccagc tccagagaac ccagagccaa cgcctagtcc taaccctcag
    21361 ccaaatcctc aaccagaaac caacacacct agccctcagc cacctgcaac agagcaaagt
    21421 gaaaacactg ctccagcagg acaaaactaa gaaagggcag ccagagctgc tgtagcttag
    21481 ttacacttct tagtacaggc aataagggct tagctactga aataatgcta aacttacgac
    21541 taataagctc tctgataaaa agaggcttta ggtgattaaa aacagctggt tctaaaagga
    21601 ttccagctgt ttttgtgctt cttaattgat tttgaggtag gaagagaagg gaggcttaat
    21661 caagtcgata agtaatccca tatcctctcc taactctcta tcagcttggc tatgattata
    21721 gagcggctca cccttacgcg ctttggtgat tcgtcatgga tattctgact ggcttgacca
    21781 tttgagtttt ttcctcagtg tcactcccta agacttttaa gggactgacg aggtgattag
    21841 catgcacaac aaaaagccct taaacacacc tttaaggacc ttgtattcag cttaatgcct
    21901 ctatagtatc agggatattt gttaaggcag ctctcagcta aagacttgtg ataaagacct
    21961 atgcctatcc gaccactagc tagagtcaag ctgtgcatag ctcagcctct atgactaaca
    22021 gaaaccagag gcagcgttag atcactttgc ttagcttaaa cctcatagcc catgagaagc
    22081 ccttcagctt ctgcatagaa gctgcatagg cctgaggctg ggctggtttg aatctctgct
    22141 tctgggtaaa tcgctctaat tttttccgca atttgctcac agatcttagg gtttttggcg
    22201 tgggagataa agactcggcc tcctttatag cctgcctttt gaatctcttc taaaacagct
    22261 gacactgcct ttttttgacc tctggccttt tgaagcagct caagcgtgcc ttccttactt
    22321 gcctgtccta ccattctgat gtttaataag ccaatcacct taccaatgag cttattcaga
    22381 cggccatttt taaccagatt atcaaccttg gccaacacaa aaacaagcct ggttttttcc
    22441 tgataagctg taattttctc aacaacctca tcaaaagaaa gcccctgatt gatcaaccgc
    22501 tctagctcta acacaatcaa atccatctca ccacctgctg acaaagagtc aatcacatgg
    22561 atattggcat tcggattttc ctcaagcaag tcattttgag ccaatctagc actattgtga
    22621 ctgcctgaga gcgtaccggt aatggtaatg gcaatgacgt tatctgctcc cctgtaggct
    22681 tgtaaaaaag catcaggact tgggcagctt gaggttgctg gcttagagga ctgatacata
    22741 gtctccatca tttgatcaat atctagacca tcatcatctc taaaaatatc tgaaccaatc
    22801 tgtagggtta gcggcacacg ctcaaagcgc aggtgattgg attggctttt tagggctcta
    22861 atatcgcagc ctgaatccga tacaattttc caggtcattc gttttcctct tttccttcat
    22921 agtctgtttt ggttgacaaa gtaagcattt tcccataaaa ttatatcatc actagctaga
    22981 cttttgctag ctaaacgaca tcagatgtaa cacttgaaag gtatttgtaa tggctggtaa
    23041 accaatttct aaacagtccc ttcaaaattt agcccactgc aatcaggaat ccagacggtt
    23101 aacacgagaa gctattgaaa ttgctctgct tagcttacta gaaaagaagc ccttaggaca
    23161 cattaccatt tcagaattgg tagctagagc tggggtttca agaaatgctt tttaccgcaa
    23221 ttacagctca aaggaggata ttcttgagtg tctgttgact tctgttatca gacgtatctt
    23281 tcgtggactg aaggcctttg atctaaagac acaggcctat caggcatggc tttatctgtt
    23341 tacagaggcc aaaaaagaag cgacgctact tagtattatc tttaaccatc acctgcagca
    23401 gctcttgacg cagatggtta ccaagcgttt gagagcctac caaaagtggc aggaaaaaaa
    23461 gctgtctcac tacgcactgc tcttttggag caacgctatt gtctcagtcc tttccaattg
    23521 gatttctgat gatatggttg ttcctgctga ggagatggct gctatggggc tgcccttatt
    23581 agcctagttg tctctagatc acctatagct cctagacaac ttcccaagaa accaagcttg
    23641 cagcatcaga caggacgctt ggctggcttg acttaagcac tggcactgcc taccaagata
    23701 tgtactagcc ctactacagg caaggtgtga cttgtcgctc gctgttgtgc agaggcttaa
    23761 aggctcttac atttagctgg acaataaaaa aagactgaag aggctggctg gattagcctg
    23821 ctcttcaatc cagaacctcc tttgttggag gttttttcgt gttttatttt tcagtcgatc
    23881 tcacacacct aggcttgtgg tgttccaaga cagctcagct ctagtcaaca cctctaaaac
    23941 tgagcttatc atctctagct tttggaggcc ttttctgacg ggctggtttg actgtgctta
    24001 agagcccttt gtcaatgcaa attgattaat ggcatgggcc acgcctgctt gatcattgga
    24061 gaggcttacc ttgtcagcga cctttttaat tgcctcatca gcgtttccca tagcgacacc
    24121 taagccagca taggctaaca tttcaagatc atttgctgca tctccaattg ccatcacttg
    24181 gtctgggcgc agcttcagat cagcggttaa ttccttcagg gcagaggcct tggtcacaca
    24241 ctccggcatt acctctagga ttgtttcttg actgcgaacc acactaaagc ttgcgctgag
    24301 tttttctcta acaagagcct caaaagtatc tagggcagcc ttttctccca tgtacatggc
    24361 ctgaaatatg atttgactgc tgttggataa ctgagatagg ttagtagcct ttacctttgt
    24421 aaaaaccaaa tcaccatcag cctgaaccat atctggaacc ttgctatcta tcacaagata
    24481 atcacgctct ccagtcaggg tgaggtaaat atctgaaaag ggctgagaca gctgataaag
    24541 gtgctcaata gctgaaaagg tcaggctttg ataatgtagc agctcccagc ttgggctcct
    24601 ataggtgcta cagccattgt ttaaaataag gtactcctcc ttatcactca agcctaattg
    24661 ctcaaaatac ggccttgtcc cagactgggg gcggcctgtg cagagaacaa cttttatccc
    24721 ctcttgtgca gctgcttgga tagccttaat attctctttt ggaatgtgct ttttgctatc
    24781 aagcagagta ccgtctaaat caattgctat aagctgaatc atcgtctcag tcctctttcc
    24841 attttatctt aggtaggtgc cattgtcttt tgttgccaat catacgcatg actgtcaata
    24901 aaacaaccag caagtagcat tcaacatttg aagtggccag cttaaaataa agcacaagtg
    24961 ctgctataat agaccagcca gcataaatct cacttctaag aacagttggc ttacggcctg
    25021 ccaggacatc tctgaccaca cctccgcctg cccctgtaag aaccgctgct acaataacag
    25081 cgcttaaggg ctgggctagt cgaacagcat gtagagcccc ctgaacacta aaggctgcaa
    25141 gtccgatagc atcagtcagc accgctgctc tcacccagcc cttagccaca agcttaggaa
    25201 atagcatgat cagaataata gctataaaag cgcaggcaaa ttctggtctt tgtccccaca
    25261 aggcttcaat aggcagcccg atcagggtat ttctaatagc cccaccacca aaggctgtga
    25321 caaagcctag aataaaaatc cccagaacat caaactcctc ctccatagcg acaatagcgc
    25381 cggacaaggc aaaggctatc gttccaataa tgcttaaaag ctcccacata tcaattgtca
    25441 taactcacct aatgcttcct aatcccctat tagtctacca tctttttaat caaaatataa
    25501 gtcaaaataa gagcaaggtc ctcaaaaatc ctactgatga cctgtttttg tttgcaccaa
    25561 agatttagcc cctatatagg ctaggctcct agtagcagga gttaggagcg atagcttgcc
    25621 aaattcacag ccttgttatt ttccatgaga aagggctctg ctgatgtctt ggtttgatag
    25681 gtcttgtatt tatggtagag gtattggtag caatcctgtt tttgatcaaa gaggatggct
    25741 tggtagggct cttggaagga caatttctca acaaacagat acttgctctt atactccact
    25801 agcactccca catgaccaat aaaaaggtaa tcaccatcta gctgatcgtg aatcacaaca
    25861 gcaagcattt tggctgggcc attaaagcta acagctgaga aatgctcttg catatgcttg
    25921 gcatgcacct gaatatcctt ggtggcttcc gttttcactc ttgaaaacag ctgcttaaag
    25981 cgctctgtct ctgcctgtgt aaagagctgg cttgtggtaa tggcgtcctc gtccataaat
    26041 aaaagcgtat catcactgct ggtaggcgca atcgtcatgc tatcctttag aagcataaag
    26101 gtgttgatcc ggcaattagt tccaatgaaa ttgccttgct tttgcgacca caactcatcg
    26161 attgctacca catcatagtc aggctgcttc tgataggtaa aggcccctgt caagcctgtt
    26221 ttgccaacta ggctattata ttcttgtaca ccagccataa aggcattgac attagcttcc
    26281 ttcagctgat gtgatagggc agccctgacc tcctgctggc tctttgcact gttcatgttg
    26341 gataggaaaa gacgtccctt cttagcctgt ggctcttttt gctcctgctt gggctgatca
    26401 gactggtgag aagcctggca agccccaaga gttgccgtag caaggattag caaagacatc
    26461 attacttttt tcatcataac ctccttttta atgagtcatt caagctggta ctctccatca
    26521 tcaccaaatg agattatcag cagctggcag ctaatacgag gttgctacaa cccacttgtt
    26581 atctctttat gtcatgacct catcgttacc agtatagcat aaaaaagaaa agcaccagct
    26641 cttgaagcct tgcagccctt gtgccggtgc ttttcgttag gagattacac tgaaatagtt
    26701 tttgtggtag ctagctgctg ataccaataa gcgctttttt tagggtaacg cttttgggtt
    26761 tcaaaatcaa catagaagag gccataacgc ttatcatagc catttgacca agaaaagacg
    26821 tccatcaagg accagataaa atagccctta acattagccc cagcaccgat agcgtctgca
    26881 atcacagcca aatgctgctt gatgtaatca attctagcgt catcatcaat cctgccatca
    26941 atacaggtat ccttgtagcc aaggtcattt tcagtgatat aaatcttttt atagcctgga
    27001 tagtctgcct tgatccgcat gatttgatcg taaagcccct gtggatagat catccaatcc
    27061 cagtctgtac gcggcacatc aacatcaaac acgcgttgac caaccccctt tatctgatat
    27121 ttggagccgc ctttttctcc cttgccatta tgaatgattt cggtctcacc atggctaata
    27181 ataagccaga cttctcatca cgtaccttag tggctggcag gccatattca gggtctagca
    27241 ggatagagga ggcatagggg gttagctcct ctgataccag agcctttagg gcttcgattt
    27301 gccaaggagc tggctctgtg tcttggtggg ctgccatcat gcgctttaaa gccccgcgtt
    27361 gatcaaaggc caaggccgaa atgattccct tacgactgac cttttctaaa taagcttttt
    27421 tgtttcttgt taatgtcatc ttatacctcc tctacttgaa tacggtcaaa tagctcatca
    27481 aaatgtgcca tgttaacatg acctgttctt gtttcttgcg catttaacat gcctaaaaca
    27541 ttggcttttt tcagaagcgt ctcatcgtca tctccttctg ccaaagccca agcaatccct
    27601 gccacagtag cgtcaccaga tccaacagga ttgactacct caattttagg aatggtaaca
    27661 cggtaaaacc tgttatgatg tttggcaaag gccccttggg caccaagaga aacaataatc
    27721 cattctatcc cttcaaataa aggttgactc aacagagaga ttaaacgttc ctcatctaat
    27781 gtgacaggtt ggcctatcaa atcctccaat tcttccaaat tgggtttgat aacagttggt
    27841 ttatctttgc cagccagtac cgcttttaaa ggagcaccag agcaatctaa aaccactttg
    27901 ctgccataga ctctcgccat agtaatcaag tcttgataat agtgagcggc cagaccctta
    27961 ggcagactgc ctgaaaaggt taagacatca aactgcttag caataatact catgtggttc
    28021 aaaaagcctt cggcctcgtc catatcaatg tagggaccag cttccagaat ttccgtctgc
    28081 atgccttcat gtaaaacagc aatacaattt ctcgtttccc ctttgatttt gaagaattgg
    28141 ttagaaatgc cctgttcttg taactgatga atgacaaagt cacccagttt cccaccaata
    28201 aatcctgttg ccacaactga ctgaccagct tctgctaaca ctctggtcac attcagcccc
    28261 ttaccaccgg ctgtttttgt cgttctgtca acacgattaa ccgtgtccaa agtcagacga
    28321 tttagaggat aggaaatatc aatggatggg tttaaggtta ccgttaaaat catcgcttct
    28381 ccctaatcgt ggtagtcacc gcgatcccat ttgtccaaaa actctgtaaa gaagtcagga
    28441 tcttcttggt tagcattatg actttccaaa tgggctatct tagcaattaa cttcttattc
    28501 tcttcggttt ccttatagtc tgcctttata aaggcctcaa taatatcaca catcaaaagc
    28561 tcacctgtga ttttaccacc aaagccaatc acattggcat tcaattcttc tttggcataa
    28621 agcgctgttg tcatatccct aacaagcgct gagcgaatgc caggaacctt gttgacagca
    28681 ttagtgatcc caacaccagt gccacagata cagacaccaa gatcagctag gccattggcg
    28741 acagcctcac caaccctttt cccaaaaatc gggtaatggg tgcgggtatg gtcataggtc
    28801 ccacagtcaa tcacttcata gccctttgat ttcaaaaaat ctgaaacagc cattttttca
    28861 tcagtcacaa tatgatcaca gccaatagca attttcatga tatcctccct tcgttaagcc
    28921 attttattga gcatgtcaac acgaatttga tgacggccac catcatagtg accagtcaca
    28981 aaacctttag caatattctt agccaattct tgacccacaa tttctgctcc catggtaatc
    29041 atgcgggcat tgttatgacc gcgagtcatg taggcagagc gttcatctga cacttccgca
    29101 gcgaccatac ctttgatttt ggtagcgacc ataaatggcc ctgctccata agcatcaatc
    29161 ataatgccta gactttcctc atcagccttg agcgccctag caactgctag agtattgtca
    29221 acaaagtcat cagcaatcgc cgtcacatct gtcacatcaa agccttcctg ctgcaaaaag
    29281 cctttaatag cctcttttag atcatttcca tgtgcatctg cacctaagat aatagtcata
    29341 ggatctcctt ttattgtcat taccgttcaa aattgtttat ttttgttttg ttttttatta
    29401 ttttgttgtt tattgaaaaa agagactgtt tatgctatta tgagttaaca atacaccaga
    29461 gaaagtagcg gcctatgctt aagcgtgaaa gattgttaac aattatggaa aaggtaaacg
    29521 ccaacggctt tatcactgtc actgatatta tggaaagcct aagggtttca gatatgacag
    29581 ccaggcgaaa tttagatgag ctagcaaggg ctggaaaatt agtacgtatt cgtggcggtg
    29641 cccagagcat ttctatgcct caaaagctgg agcgttcaaa cactgaaaag ctaaccgtac
    29701 aaattgaagc taaaaaagag attgccagat acgctagtca gctcattaat gatggtgaga
    29761 ccatttttat aggccctggg acaacactag aatgcttggc tgaggctcta atcaaccgtc
    29821 acatccgtat tattaccaac agtctgcctg tttttacgat tcttaataaa agtaaaactg
    29881 ttgatctcat tcttatcggt ggtgagtacc gagccatcac aggagccttt gttggcagcc
    29941 ttgcaagcca gaccatctta tccttgaagt ttgccaaggc cttcatcagc tgcaacggta
    30001 tttataaaaa tgacattgcc acctacagtg aaaacgaagg ggttattcag cgcctagcct
    30061 gtgacaatgc catcgaaaaa tacctgctcg ctgacaacca aaagtttaac gcctatgact
    30121 tttacagctt ttatcacctt gacaatatcg acgccattat cactgactcc aagattagtg
    30181 acagcgttaa ggagcgttac cgccaatttg ccaagctctt aatcgcaagg ccagctgaca
    30241 atcaggtcag cagctagaca gcctgcctct ctatctgttt ccaccctgag tccagcaggt
    30301 aaacaaagct atcaaacgaa atagcatcat aaaagcgcat gaagccacta atattgcaat
    30361 ggggcttcat gcctttttta acctatcaca cgttaagcaa agcaaaaaga ggctaggaca
    30421 aaaatccttc ctcttttaaa atcgtcaaac tatagagttg attggagggc tcttagccct
    30481 catttttcaa gcgatgtggc ctttttaatc agctgctcga gggtggataa cctaatcaac
    30541 atcgccaggt catgacgatt gaatggttat tccactcttt ttctacgctg agggctgtga
    30601 aagggctcat acgacagctt agccgctttc taacagctat ttacctacct cacctcttaa
    30661 cgagcagaca gcctaaatgg tatagtccag ctgatcaaga ctctttttat ggtcaaggtc
    30721 aatatcaaga aaggtcatct gcttgatatt gataaggctg gctacaattg ataccggaaa
    30781 agcaaccacc gcttgattga agagactaat attactattg acaatgcgtt ttgctgctgc
    30841 caaggctgca ttttccttag caatctcatt ttgcaggctc aaaaactgct cagaggagcg
    30901 catttccgga taagcctctc ctacagcaaa aacctcattc aaggcctgct cctgtgtcct
    30961 catcacatca tttgtttcct ccaaggaaag cccctgacgc agcttcacga gttcagtaaa
    31021 gaccttttcc tcatgcttgg cataggactt agcgattttt agcatttccg aaatggtatc
    31081 atatctcttc tcaagagcaa tatcgacatt tcgtttagac tcctctataa cgattcgata
    31141 cctttctaat ttgtttctca ctccaataag ccatagtata gtcatgcaaa gaataagtgt
    31201 taacatagat gacgtcactg acataaaaaa gcctccttaa agctgatgat ttagtgtatc
    31261 caacaagcgg tacatcttaa caagcttgtc ttgaatgttt tcatattcgc tacttaacga
    31321 tagcttttca atagcccctc tagagctagg ggttttcaag agctgttgac cggaatagaa
    31381 ggacacaaca acagtatcac cattcatata aactgctaca ggcatctcct ctctccattc
    31441 atcaagcact gccagcatat aaggatttaa gagcattcta gcgcttaatt catctgtgca
    31501 gtacacattg tacgtttcat taaagcgaat gtcctccatt tccagctgca cctcaccctt
    31561 tagcttagcc ttgtagccac tatggacctt ttctctgccc aaaaagccct tttgagtcgg
    31621 cacaattcta atataaccct tgatagctgt atgatattta gccagcagca cctgtccgtt
    31681 aaaatcagtg acccgatgcc agttatcatc ctcattttcc tcatggtagg cataaagatt
    31741 gcaaaattct gtctgcatgt catctccaaa aataatatgg caattactgt cataccatct
    31801 ggaggacggt gttgcaagct ttagtaagga gagctcaatc cctgaatagt aatctatctt
    31861 gacatctggc agggcctctt gtaaaacagg cagcaaaaag tgatccacat aggagagctc
    31921 atttgctgtt ttgaatgttt tcagccgcgg ccaaaccaag ccccccacaa agataatgag
    31981 aaataaggca agagatcggt caaccatgcc atacaagatg attgcgccta tcaccattgc
    32041 cagccagccc agattattct ttctagcatt tccactcatc tcgcttttaa tttgctccag
    32101 cttttggtga tgctcaggcg aagcttctat agctctactc ttctccaaaa caataggatc
    32161 tgtcaatcgc ttagtatttt cgttcatctc acttactcca gatacttctc catcagcagc
    32221 gctcagctgc tcttgataac accagtcact ttatgctttt gcttaaccta taaatgacaa
    32281 ttgcgttaca gctaatttat aatattatac catttttaaa ctattttttc tattattata
    32341 tttaaatgac gctcaataat aaccacataa tgttaatata gacatcattg tgctcttttt
    32401 tacctaatca tgttgtgagc aatacccccg tttatcagcg gaaaccataa aggcctctat
    32461 gagatcaaga ctatcagcgc cagcccttct tttggagtca ctattcagct tgttcttcgc
    32521 atgctgtctt tgcctgacca tgattcagct gctctttttg attgcttgtt atgctcactt
    32581 tttccgtctc atgctgagca agaaaaaaca gcaaaccctt gcttggttta ctgctcttct
    32641 gttgatgtta gtcaaaaaat aagccgggag ctaatgacac cctattaact cataaagcct
    32701 gttatccttt ctttgtcata gaacaattca cttagtctat tctcaaccaa aatacgaagc
    32761 ctgcttaaac cgtcttctca tattaacagc taaaaagtgg tgtcaatatg aagaaaccta
    32821 tgatcggtaa caataatagc acctttaaat ctctcagcga taatgtaagg ttatcctata
    32881 cctgtcatat ttttcggtgc tatttgccat atcaggttgc tatagcactt ggtggcttct
    32941 ggtagcctta accaataaat gatctgcttt tttattcctg ctctttgttt tgtttatgcc
    33001 ttttgtcggc gcaggccttt agctttacta tactgacggt aaggtcggtg agagccttta
    33061 ccatttttta tgccttaatc gcaaagcatt taacaccact gatattgagc taaggctcat
    33121 cgcaaagcca gccagcattg ggcttaatag agggccgcca aagacatgaa ggatacccat
    33181 agcaacgggg atcattaggc tattatagct aaacgcccaa aataaatttt gcttaaccac
    33241 tctgatggtt tgacgactga gctctaggca ttccaccaca tcacgcactg ctgaggtcat
    33301 caggataaca tctgccgcct caatcgcaat atccgtacct gagcctattg agattccaat
    33361 atccgctagg gtcaaggccg gtgcgtcgtt gattccatca ccaaccatag caaccagctg
    33421 tccgctagcc ttcaaatccg cgataatctg ggccttttga gcaggcagca cctgactaaa
    33481 gacctgatca attcccacct cattagcaat cgcttgagct gtgagggcat tatctcctgt
    33541 tagcataacc gtttgaagac ctaaatcctg caaggccctt atagctgcct tactgtcagc
    33601 ctttagccta tcagcaatca gcaataaagc acatagctga ttatccttgg cataatacac
    33661 tacggtttgc ccctttaagg cagcttgctc ggcataggtc tgagcagcgc ttatcgcaat
    33721 cccctgctgt gacatcagct cactattgcc aacagctaag cgatgctggt caatcacacc
    33781 agtgacaccc aagcccacaa gcgattgaaa atcagtcaca gccagcaagt catagccctt
    33841 ttcctgtgct actctaacaa gcgcttctcc aagagggtgc tgcgaatact gctctaagga
    33901 agccacctcc tgaagtccct gcttctcact agcagcaagg gggatgatcc gctgtagctg
    33961 agcctgaccc tctgtcagcg ttcctgtttt atcaaaaaca attgtccgca cctgataagc
    34021 cttctctaaa atatctcctc ccttaaaaag gatcccctgc tcagctgcac gacctgagcc
    34081 aaccataatc gcggtgggag ttgctagacc cagagcacag ggacaagcaa taatcaaaac
    34141 agctatagct attgtcaggg caaaatcaaa gctctctctc ataacaaaga gccaaaaaag
    34201 aaagctcagc agggataaac ttaatacgat agggacaaag actcctgata ccctatcagc
    34261 aagtgcagca atcggagcct tggcttgctg tgcttgctcc accagctcaa taatctgtga
    34321 aagcaaggtg tcattgccaa gcctagaggg ctttaccctt agcgctcctt ggccattgat
    34381 tgtgccagca aacacactat cacctgtcac cttatcaact ggtaggcttt ctcctgttag
    34441 catggactca tcaaccgtag actgcccctc tactatcagc ccatcaacag ccacccgttc
    34501 acccggttga ataaagcaaa tatcctcatt agtcacctgc tctaagggaa taagctgaag
    34561 tgctccctca cgaataaccc tgacatcagt tacccttaag gacattagct tctgaatagc
    34621 ctgcgaggcc cgtcccttgg tacgcccctc caaatagctg ccaagggtaa tcaaggtcag
    34681 aataaccaca acagattcaa aataaagctg gtgagcaaat tgagcagctc cagctacaat
    34741 cttaaaacag ctatatgagc tgtaaataaa agcaaagcta gtggctaagg tcacaagcga
    34801 atccatatta ggccgcttct ttatcaatgc cttaaagcca ttttcatagt actgccgatt
    34861 caagaaaaga acaggcaggg tcagcaaaag ctgaacaaga ccatagctta tagcatgcga
    34921 ctgaggtgct agagcgaccg gcagcaccaa tccaagcata ggtcccattg caaggtatag
    34981 cagcggcaga ctaaagagag cagaccacag aaagcgatac cattcattgc tagcctgctc
    35041 ctctaggcgc tctagttgcc ctctcatatt ggtctcatca agcagctctg ctctgtagcc
    35101 tgcctttctt actgcttgaa tgagctctgc tgagctgagg ctgtcagttg agtagctcac
    35161 tgatagcttc tcagtcgtca catcaacagc tgccccctca acacctggca gttgcttaac
    35221 agcctgttca atcgctagag cacaggaggt gcagtgcatt ccctctaata gataggtctc
    35281 tttaacaatc atatcctctc ctttttctga caatgacatt gtcctggcac acaatcacac
    35341 cttacatggg atactgctcc gactttttta gcctctaaga gcaactgaaa agcctgaata
    35401 tcttccaggg tcattggggt atcctttagt aatgccagca acaagcggct atggtggcgt
    35461 tgacacatgc catcaagcct ctctcgtagc atagcaagct gtcgcctgtc ctgatcaagc
    35521 aaggactggt aaatatagga ccgtccctgt ctatcagccc ttagggcttt tttcttaacc
    35581 aagcgtccaa tcaaggtctt aacggtagaa tcagaccaat ggtgcttttc atgaagaata
    35641 gcaataatct cagagctctt catgctccca ttagcccaaa caacacgcat aacctcccat
    35701 tctgcatcag atatcgtatc catattgcta cctctctttc atctacggtt ttattaagta
    35761 tagcttattt gtttacgttt gtaaacaaat aataactaaa aaaggtctct ttatgagaaa
    35821 cagcgtcaaa aaaggactga cagctaaagt cagcagctag cttttaatag tctgaacttt
    35881 ccagtcttat ctgattaact ttatattgac aaaatgagtc cttgtatatt actatatgac
    35941 agtaatactg taatgattaa ggagaaaaca ttgacgtatc ttaaaagaca gctaattcta
    36001 ctagcccttc tactcacagc tataggtagc caaacaatcg ttcaggccag cacgcgatcc
    36061 tggaaaagct ggtttattga gcaatatttt tggcttaaac gagacaaaag ctattatgcc
    36121 gagcaggatg agaatacctt ctacaactac gtcaagtcag ctggtgaaaa gagcaatcaa
    36181 ggctttaatc tcactcaaaa tgaggtcaac ggaacattaa agacagagta tagagacaac
    36241 atgcaggttc acagctggaa tgaaaactct actaatccat caaatcaaaa ggtcattctc
    36301 tatctgcatg gtggctccta cctaaacaac ccgacctcat accatattga catgctcaaa
    36361 accttgtcaa ctagccttga tgctaagatt gtattgccga tttacccaaa ggctccgacc
    36421 tatacctatg atgtcgctat gccaagatta gttagtcttt atcaggatat tctaaaaagc
    36481 actaataaca atgctaacaa tatcaccatc atgggagact cagccggagg cggtctggca
    36541 ctaggtttgg cactagcatt gaaaaatgaa gatattaagc agcctaagga cattatcctg
    36601 ctctcacctt ggcttgatgt caccctatca aatccagaga tcccaaatta cgaagcctct
    36661 gatcctatct tatcggcttg gggactgcgc atagtaggtg atatctgggc acgacgcggg
    36721 gaaaataaca ctaagcaccc ttatgttagc cctatctatg gagatacaag caacctagca
    36781 cctatcacca tgtttgtagg aactcatgaa atcttctacc cagacattac aaaatttgat
    36841 ggtatgttaa aacaaaaagg acataagcac cagctatttg tcggggaaaa gatgaaccat
    36901 gtttatccta tttacccgat tgaagaggcc aagacagcac aataccaaat cattgatacc
    36961 ataaaaaaag agtacgaacc ccaaaaataa taatacaaaa atgcctacca gacttgagtt
    37021 ttttgccaaa gcctggtagg cattttctga tcacagcatg actactgttt cttttctagc
    37081 tcacggagca attgatcaat tttattacca taggcgatag aattgtcctt ttcaaaaacc
    37141 aaatccggaa ttttatacat ggttaattgc ttaccaagct cacgcttaat ggttcctgtt
    37201 gcttttttta agcctatttc agccttttga ttgtctgaag ctaggtcact cataatggta
    37261 tagtaaacct tagcaactga caaatcgccc agcatttgca cttctgtgat cgtaacaccc
    37321 tgcacacgtg gatcacgaac ctttttgtgt aaaatctcgt tgacctcacg cttgatttcc
    37381 ataccaacac gatcaatacg atgatttgtc atggcccttc ctttctattg tcaaatagta
    37441 caggctctca gtagctcaat aacaagagaa aagcttgatg actttcaagc ctttttctct
    37501 attaggctga tggctatact attaatagtg actgttcaaa tcaagtggtg acattgtcta
    37561 ttgtcttgag acgaggctat ttaagctact agccaccacg attatttacg ggtaatttct
    37621 tccatgacgt aagcctcaat ggtatcatcg accttaatgt cattaaagcc ttcaatcatc
    37681 aaaccaccct cttgggcatt cccaatctcc ttaacatcgt ccttataatg cttaagactg
    37741 gctagcttac catcaaagat aaccacgcta tcacgaatga cacgtacact tgaatcacgc
    37801 gttaccttac cattaacaac cataaagcct ccgattgtcc caaccttaga gaccttaaag
    37861 gtttcacgaa taatagcctc accaagcatt ttttcttgat actcagggtc aagcttacct
    37921 ttcatggctt cctcaacctc ttcgatcacc ttataaataa tgctatgcaa gcgaatctca
    37981 acatcgtctg tatcagcctg ctgacgcgcc tgtggtgttg gacgcacatt gaagcctatg
    38041 ataacagcgt ttgaagcctc tgccaaggtc acatctgact cattgatcgc accgacagca
    38101 gagtgaacaa catttactcg aacgccctca acatcaattt taaggagtga ggctgccaaa
    38161 gcttccacag agccctgcac gtctgccttg atgatcacgt taacggtttt gatttcccct
    38221 gccttgaggg tatcaaatag gttatcaagg ctgacacgct gcgtgttttg acgttgcttg
    38281 agaagggcac gcttagcacg ctcctcccct gctgcacgcg ctgctttttc atcagcatag
    38341 accgcaaaat gatcacccgc cataggggtt tcattgagac cagtaataga taccggtgtg
    38401 gacggctcag ctgatttcac acgacgacca aggtcatttg tcatggcacg cacacgacca
    38461 aaggtgttac caacaacgat tgggtcttgt acgtgtaggg ttccttgttg gaccagaagt
    38521 gtcgcaaccg cacccttacc tttgtcaagt ctagcctcaa tgaccgtacc aatcgcacga
    38581 accgtaggat cagcctttag ctcttcaacc tcagctacca aaagcactgt ttctagcagc
    38641 tcatcaatgt ttttgttaaa tttggcagag atttcaacaa actcacactc accaccccaa
    38701 gcagttgaga tgatcccatg ctcagccaat tctgaaataa cacgctcagg attagcccct
    38761 ggcttgtcaa tcttgttgat ggcaacgata attggaacac cagccgcctt agaatggtta
    38821 atagcttcaa tggtttgtgg cattaccccg tcatcagcag ctacaatcaa aatggtaata
    38881 tctgtcactg acgctccacg tgcacgcatg cttgtgaagg cagcatgtcc tggtgtatcc
    38941 aagaaggtaa tcttcttgcc tgcctcctca atctggtaag ctccaatatg ctgggtgatc
    39001 cctcctgctt ctcctgttgc aacacgagaa tttctaaggg tatcaagcag ggtcgtctta
    39061 ccatgatcga cgtgtcccat aatggtaaca accggtgcac gctcaacaat attctcagga
    39121 ttaaggtagc tatcatcagt aaagaagcgc tcgatatcag cttcatcaac ctccaccttg
    39181 gccttagctt caatgccata atccaccatt aagagctcaa tggtatcacc atctaaggat
    39241 tggttttgcg ttgccatcac acccatcata aataatttct tgacaatctc agccggctca
    39301 cgcttgatcc gttttgcaat ttcagcaacg gtcattcctt ctgaatattc aaattctttt
    39361 ggtaattcat ggaatttacg ctctgttact ggttttggag ctgtgttgct attcttatga
    39421 tgcttacctt ttttgttttt cttgttgtta ttccagttac tattcttttg atttctcact
    39481 tggttttgac tattccaact cttcttattt ttcttttgtc catcttctag gccatgatcc
    39541 cgatcatgcc ctttgtctgg acgattttgt tttttacgac gcttatcaac cggttttgct
    39601 accgatgcag cagccatact agcaaccgac tcagtagcct tagctgaggc ttcacgatgc
    39661 tttttgtcct ctgtctgagc cttgagggcg gctgccttag cctcttgcct tgcctgttgc
    39721 tctaagcgtt tagcctcctc ttgctcacga aagcgtgatt ccctttgtct ggcatactct
    39781 gcgttttgct cagcctttaa ggcagcagca cgcgccttaa aatcaatctt aggagcaccg
    39841 gcttgggtct gcccttgacg tcctgtatcc tgttgacgac tattagcgtt aaaggaacgg
    39901 tttttgtcac gattaccagc ttgtctatgc ccatcgtttc ggttatttcc agatgatggc
    39961 ctgttatcaa agcgtctatc tctttgctga ttttgtgact tgtggccagc tcgctccgtc
    40021 tgctgacctt gtgatcgtcc aagttgacga tagtctgact tgcggtcatt agagcgattt
    40081 tgcccagcct gccgtctcgc tacctgctcc ttggcacgtg cttcacgctc tgccttgaaa
    40141 ttgcggctct ttggcttaac agcaaccggc tgtgatgctt cttgtgtcgc agcagctggc
    40201 ttttctgctg ctttagaggc tgctggctgt ggtgtagtgg ccttagctgc ttttgctttt
    40261 tgttctgcta cttgcttgtc ttttgctgaa cctgcttgaa cattcttagt cacacctgct
    40321 gaaaagctag aggcaatttt gttagcatct gcttcttcga cgcttgacgc atggcttttg
    40381 acatctaatc ctaaggattt agcacgctca acgacttctt tactactttt gccaatttcc
    40441 ttggcaattt catgtaatct tttctttgac aatttgtgtc ctcctattcg tctatttcat
    40501 aagagtcctc attttctttg aaaatccagc gtctgcaatg gcaaccacct tacgaggctt
    40561 gccaagtgca gcacttaatt ccagtgcact aaacactgtg gagacttcta cattgtaata
    40621 attactttta tctgttactt ttttagtgat atttgggcca gcatcattgg ctaaaaaaac
    40681 aagattgact tcctgatgtc gaatggcttt aatgaccaat tcctcacctg aaatcacttt
    40741 tttggcccgc tgagccagtc cgatcaaatg agataatcta tttaaactat tcaaggccta
    40801 gctctcttct tttaactttg tgatcaacat gtgcaatcac ttcatcgtaa aagctctctg
    40861 gcacctccat tgagaagcta cgattaaaca cctgtttttt ctttgccata agtgcttctt
    40921 ggttatctag cttgatataa gcaccacgcc cattttgctt gccggttgga tcaataaaaa
    40981 tctgcccctc cttatttttg acaatacgaa ggaggtcacg cttatcaatg atctcaccag
    41041 aaacaagcga cttacgtaaa ggtatttttt ttactttagg cataaaacac ctcttttctt
    41101 acacttcctc gttggttaag agctcctctg tagctactgc ttcagtcatt gctgcttctt
    41161 tttctgcttc aaggcgttca tattcactgg ctgatttgat gtcaatgcga tagcctgtca
    41221 aatgagctgc caaacgaacg ttttgaccac gacgaccaat agcaagcgat agcttattat
    41281 caggcaccac cacagtcgca cgcttaagat cgtcatcatc aaagagaacc atatcaacct
    41341 cagcaggtgc aatggcattg tagataaatt cagcagggtc atctacccat tggataacgt
    41401 caatattttc ttctactggg atctcaagtc ctgtcttagc atcatagcgc tttggatgga
    41461 atttactgat aacctttttg atgttgctgc cgccacgacc aacaatcgtt ccaatcgcat
    41521 caacattggg attgtggcta cgcacagcaa ccttagtacg gtcaccagcc tcacgagaaa
    41581 cactcataat ctcaacggtc ccatcaaaaa cctctggaat ttcctgttcc ataatgcgct
    41641 tgatgaactc agggtgacta cgactaacaa agacgttaac cccctttgga ttgttttcca
    41701 ccttgtagac atagacatca atccgatcat gtgatttgaa ggtttctcct gggatttgat
    41761 cctgatgtga gagctgagcc tctaaggaac caaggttaac ataaatgaaa cgttggtcaa
    41821 aacgctcaac cgtacccgtc atgatttcac cttcatgctg cttgtactca ttgaaggtga
    41881 tttctcgcat ctgacgacgc atcctttcca taatggtttg ctttgcagat tgagcagcca
    41941 cacgtccaaa ctcgctgact gattcttcaa aacgaatctt atctcctaac tcataggctg
    42001 agctaatggc aagggcatcg ttcaggctaa tttccagacg gctatcaaat acctcttcaa
    42061 caacctcacg aaccgtaaaa acctgaaaat ctgctgtttt atcattaaat tcaatgacgc
    42121 aggattctgc ttgaccataa cgacgtttat aagctgattt cagtgattca gtgactgcct
    42181 caatgatatc tgccttatca atgtgttttt cttcttccaa aatacggaag gcttctagca
    42241 tttctttgct cataatgttg tctaccttgc tctcaaagct tggtaaaaat cctttcttat
    42301 cttataaatt aatccattta gggcttagcc aaccgactaa agcaaatcgc tcagcaattg
    42361 ccttataatt tgacagctaa acgagcctta gccactgctt ggtaaggaat ctcaactgtt
    42421 ttgtgacgcg tcttatctag ataatcaatg gttagggtat caccatcaaa agccactaaa
    42481 tctccttgaa aaaccttcac cttatcaatt gcccgataga ggctgacatt aatatatgag
    42541 cctacagcag ccttcaagct ctcagcagtc tttaatggac gctctagccc aggactggaa
    42601 acctccagca tatactgatc tgggaaaggg tctggagaaa tcgtatctaa gagtggactg
    42661 attagctctg taagctcagc agtatcctca acggtaatcc cagaagcctt atcaactaag
    42721 atactaagga cataatcatt gcccattttg tcgtattcga tgtcgaccaa ttcatagggt
    42781 gctttaatta caggttctac gatttgggta acaatatcaa taatagctgt gtttgcgatg
    42841 ttaataacct cctttactga tgactgctat acctctatag ccttgtcctc ttgataatca
    42901 acacaaaagt ggcgagatat ttctcaccac ccttctgtat tgctttaacc tattatacca
    42961 caatcaaaat gaattgcaag aaaatcccta ctaaaagtgt caataagacc tcaaaaatcc
    43021 tattttttaa aaggagagga gatctttaac cttgcttttt tctctttcct tatcccctct
    43081 aacctctgta ttcatatgat aaaataaaat attaaagggt aaaaaagaca actaaaatat
    43141 tatttgcggc tgcttcatgg tctttaccaa aacgaaaaaa cctcccatca gaacagatct
    43201 atgcatatgc gagagaggcc attggtaact caataacatc attaataaag cttaaattag
    43261 ttcaatttgt aattttaata ccactattta tcggtaatat aagtttatct gaggatatta
    43321 aaaatattaa tgctattttt aaagacagca ttagttaatg atataataaa agctgtaatc
    43381 tccctcatta tatcataaaa acgatttcaa aaacagactt gtatttcaag tgacatttga
    43441 tatacttgaa gatgggaata ctgcttgagt ggaggcattg taggtctagt tcaacgtaaa
    43501 gcagcagctg aaatcgcaaa actaatactt aaagtgggga tcaagaatgt agcccctgct
    43561 gcagctgcag catcattaat ttggagcttt ggaagatgca tgtggtttta atgtcaaaaa
    43621 gatatagtat ttgtataaca tttcttgtta ttatttcgcg attcgtttgg tttgccctta
    43681 caggaagaag tcctttttat gactttattg ggactatatt tttaggagta gtggttttac
    43741 taattagtca aaaagtattg aaaaaattaa agtgataaaa ttattaaccc gacaatag
//
LOCUS       DARYVE010000013        39096 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYVE010000013 DARYVE010000000
VERSION     DARYVE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39096
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(93..464)
                     /locus_tag="TVW25_000623"
     CDS             complement(93..464)
                     /locus_tag="TVW25_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378280.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TVW25_000624"
     CDS             683..1321
                     /locus_tag="TVW25_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1378281.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TVW25_000625"
     CDS             1517..2053
                     /locus_tag="TVW25_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378282.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TVW25_000626"
     CDS             2916..3320
                     /locus_tag="TVW25_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1378283.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TVW25_000627"
     CDS             complement(3376..4860)
                     /locus_tag="TVW25_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1378284.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TVW25_000628"
     CDS             5219..6442
                     /locus_tag="TVW25_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1378285.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TVW25_000629"
     CDS             complement(6532..6891)
                     /locus_tag="TVW25_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1378286.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7769
                     /locus_tag="TVW25_000630"
     CDS             7056..7769
                     /locus_tag="TVW25_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1378287.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEALKA"
     gene            complement(7848..8675)
                     /locus_tag="TVW25_000631"
     CDS             complement(7848..8675)
                     /locus_tag="TVW25_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1378288.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8936..9064
                     /locus_tag="TVW25_000632"
     CDS             8936..9064
                     /locus_tag="TVW25_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1378289.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9118..10431
                     /gene="obgE"
                     /locus_tag="TVW25_000633"
     CDS             9118..10431
                     /gene="obgE"
                     /locus_tag="TVW25_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1378290.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10552..10710
                     /locus_tag="TVW25_000634"
     CDS             10552..10710
                     /locus_tag="TVW25_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378291.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10763..11467)
                     /locus_tag="TVW25_000635"
     CDS             complement(10763..11467)
                     /locus_tag="TVW25_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1378292.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11802..13202
                     /locus_tag="TVW25_000636"
     CDS             11802..13202
                     /locus_tag="TVW25_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1378293.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13212..14306
                     /locus_tag="TVW25_000637"
     CDS             13212..14306
                     /locus_tag="TVW25_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1378294.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPREVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14412..16406
                     /locus_tag="TVW25_000638"
     CDS             14412..16406
                     /locus_tag="TVW25_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1378295.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16420..16737
                     /locus_tag="TVW25_000639"
     CDS             16420..16737
                     /locus_tag="TVW25_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1378296.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16734..17069
                     /locus_tag="TVW25_000640"
     CDS             16734..17069
                     /locus_tag="TVW25_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1378297.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17069..17503
                     /locus_tag="TVW25_000641"
     CDS             17069..17503
                     /locus_tag="TVW25_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1378298.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17578..18957
                     /locus_tag="TVW25_000642"
     CDS             17578..18957
                     /locus_tag="TVW25_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1378299.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            complement(19263..20003)
                     /locus_tag="TVW25_000643"
     CDS             complement(19263..20003)
                     /locus_tag="TVW25_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1378300.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(20003..22168)
                     /locus_tag="TVW25_000644"
     CDS             complement(20003..22168)
                     /locus_tag="TVW25_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1378301.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22360..24351
                     /gene="uvrB"
                     /locus_tag="TVW25_000645"
     CDS             22360..24351
                     /gene="uvrB"
                     /locus_tag="TVW25_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1378302.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24690..24833
                     /locus_tag="TVW25_000646"
     CDS             24690..24833
                     /locus_tag="TVW25_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1378303.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24845..26383
                     /gene="dltA"
                     /locus_tag="TVW25_000647"
     CDS             24845..26383
                     /gene="dltA"
                     /locus_tag="TVW25_000647"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1378304.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26380..27627
                     /gene="dltB"
                     /locus_tag="TVW25_000648"
     CDS             26380..27627
                     /gene="dltB"
                     /locus_tag="TVW25_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1378305.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27645..27884
                     /gene="dltC"
                     /locus_tag="TVW25_000649"
     CDS             27645..27884
                     /gene="dltC"
                     /locus_tag="TVW25_000649"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1378306.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27877..29130
                     /gene="dltD"
                     /locus_tag="TVW25_000650"
     CDS             27877..29130
                     /gene="dltD"
                     /locus_tag="TVW25_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1378307.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29164..30138
                     /locus_tag="TVW25_000651"
     CDS             29164..30138
                     /locus_tag="TVW25_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1378308.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30679..31938
                     /locus_tag="TVW25_000652"
     CDS             30679..31938
                     /locus_tag="TVW25_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1378309.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     DKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32111..33811
                     /locus_tag="TVW25_000653"
     CDS             32111..33811
                     /locus_tag="TVW25_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1378310.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33840..35972
                     /locus_tag="TVW25_000654"
     CDS             33840..35972
                     /locus_tag="TVW25_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1378311.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSIAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLAFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36048..37352
                     /locus_tag="TVW25_000655"
     CDS             36048..37352
                     /locus_tag="TVW25_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1378312.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37353..38213
                     /locus_tag="TVW25_000656"
     CDS             37353..38213
                     /locus_tag="TVW25_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1378313.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38238..39068
                     /locus_tag="TVW25_000657"
     CDS             38238..39068
                     /locus_tag="TVW25_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1378314.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10877 a         7381 c         9049 g        11789 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggcctta aaagcctaag gctagactag tcactggctg ggttagctgc
     7801 tgaattgata gtaaaaaaga ccagtcttag actgatctgt agggtgatta gatcgcccat
     7861 tctcctcctc ggaagattgg aatgacttct ccgtctttgg taatgccatc gatatccatt
     7921 tgttcagaac caatcataaa gtccgcgtgg gctgttgagc gatttaggcc agccgcttcc
     7981 caaatgtgct gctcaggcat tccaagtctt aggtcagttc ctggtgccct gtagtgaagg
     8041 ctgtcaaact gataatcatt gaggagcctt gccttttttt ctaaacgttc ctgatgttgg
     8101 tcccaggcct tgacaggatc tgtctcgtaa atgcgattca ttttgaaaat ggcatcccac
     8161 aaagcgtcca cctgctcttc ttcgcttgtc aggtttggaa aaaccatagc agcccattcg
     8221 ggaccggctg cagctgctag attccagctg actttgttgg cctgagtggc agcccgctgt
     8281 ttttcaagag caatagctgt tgcgcgtgtt gctccagcta gcctatcaga atcaatatca
     8341 gcaaagacgt ttggattggc agagcgaatg actaagcggc ttgctttttg atcaaggaga
     8401 taatgtgact gttcaacgac ataatctggt acctgcaaga gacggtcttc atcagcctta
     8461 agaagcttct cgcgtgtgat ctgatcgtca ttatagtcaa caagaacctc agctgcacca
     8521 gcctcatagg cttttttggt taatagccgc gcaagcttgt gttgctctac tgcaatagaa
     8581 atgagtagtg tgtgaccttt ttgaatgttg actccttttt tgataagaag gttagcgtat
     8641 ttttcaagat aatcgtcaaa atgtggcaaa accatagcag tctcctaata tgttaatgtt
     8701 gcaaaattta atgtatcata tttgcgacta tttcacaagg agctagcctg tttcataggc
     8761 taaatgtctc ctagaatgcc tatcgtaaaa ggctcagtgt tggttttctc tgatgagtta
     8821 aaaaacgatc ccttttttga tcagtttgcg ctgcccttgc taatagatat ttgcttaata
     8881 gcgacattcg tgttaagata taagaggaaa aaatcaatag atgaggtatt taacagtggc
     8941 atttggagaa aatggacctc gcaaaaaaac tgcctttgaa aagttgacaa cagttgttgt
     9001 gatcgtgatg gttcttgtga ctgtcggtgg acttattgcg ggtgccctgt cagtattgat
     9061 gtaagaaaac gctgaaaggc gtttttttag gataagagaa ggtttgagaa gaaaagtatg
     9121 agtatgtttt tagatactgc taaggtcagt gttcaggctg gtcgtggcgg tgatggtatg
     9181 gtggcctttc gtcgtgaaaa atatgtgcct aatggcggcc cttggggcgg tgatggtggc
     9241 aagggtggct ctgtcatttt caaggttgat gaaggtttgc gtaccctaat agactttcgc
     9301 tacaatcgta agttcaaggc caaatccggt gaaaaaggca tgactaaggg catgcatggt
     9361 cgtggctcag aggatttgat tatctcagtg ccacagggaa cgactgtgcg tgatgctgaa
     9421 accggtaagg ttctgacgga tctggttgag catggtcaag aatttgtcgt ggctaagggt
     9481 ggtcgtggcg gtcgtgggaa cattcgtttt gcaacgccgc gcaatccagc acctgagatt
     9541 gctgaaaatg gtgaaccagg agaggagcgc caattagagc tagagcttaa gattttggca
     9601 gatgtgggac tggttggttt tccgtcagtt ggtaaatcaa cgctactaag cgtggtctca
     9661 tcagccaagc ccaagattgg tgcttatcac tttaccacta ttgtgcctaa tctaggtatg
     9721 gttcgaacca aatctggtga gagctttgct atggcagatc ttccaggctt aatcaaggga
     9781 gctagccagg gtgtggggct tggcactcag tttttgcgcc atattgagcg tacacgtgtg
     9841 attctacatg ttattgatat gtcagcagct gaaggacgag acccttatga ggactatgtg
     9901 gcgattaata aggagttaga agcatataat cttcgtctta tggagcgtcc gcaaattatc
     9961 gtcgccaata aaatggatat gccagaggca aaggagcagt tgcagcgctt caaggaacag
    10021 ttagctgctc agtatgatga ctttgaagaa ctgccaataa ttttcccgat ttctagcttg
    10081 gcacatcaag gcttggatag cctattagaa gcaacagcag agctattagc aaaaactgat
    10141 gatttcttgt tgtatgatga ggctgatttg gctgaggacg aggcttatta tggctttgcg
    10201 gctgaggaaa aggcctttga gattagtcgt gctgatgatg cagcttgggt attgtctggt
    10261 gagaaattag agcgtctctt tgtgatgacc aatctggagc gcgacgaatc tatcatgaaa
    10321 tttgctcgtc agctacgtgg catgggtgtt gatgaagcgc ttcgtgagcg tggtgctaag
    10381 gacggcgaca ttgttcgcat tggcaagttt gagtttgaat ttgtagacta atgacaaata
    10441 ccaagcttag ctgttttttg tagcaagtga tgctgagtca tatctgaagt aggctgtttg
    10501 ctcaattcac agcaatgagg tcttggttga tgtgagctag ggaggttttt tatgggagat
    10561 aaaccaatat ccttcaagga taaggacggt aactttgttt cggcagcaga tgtctggaat
    10621 gctgaaaaat tagaagaatt atttaatctc ttaaatccca ataggcgttt gcgtttggaa
    10681 cgtgacaaat taaaaaagga tgaagcttaa gtgcacttcc tctcaatcgt tagatttagt
    10741 gtctaacttt tgagggtgca cttcaaggct tcgtcctttt ttgatgcttt ttttcttggt
    10801 gatgctgcaa atgtagccaa ttaaaaaagg tgtaaatgtc attaacaaga aaggctgcaa
    10861 aacaaatgac cactgcgtat tggctggtat ttgcttgagc agcatagagc cacaggagaa
    10921 ttaagaccaa atcattaaga gcataggcca aggcaaaata agggctacgt ttgtagctta
    10981 agtaggctgc tgaaaaagag gtggcaatag ataaggtaga aacaggcaga taggctgtct
    11041 taagataggc taagatagca tagaacaagc tggtaactag tatggtaaga accactaagc
    11101 gcagccggtc tgctgttgtc aagcgtgaga tggttacctg agatgtctgg tcttcaaatg
    11161 ggtggcttag ccaggtaaac agtgacaaaa tagccatcgg cagggtcatg aagagatagg
    11221 ttatcagctc cccgtaataa ctgtttaata gtgacagata ggcataaata agggagaaaa
    11281 taatggccaa gctctgtcca atcggatttg ccttggcact aaagattaaa gctgtcacac
    11341 cgattaagga agctatcagt gctaagggag cttgttctcc aaagaaaaag gcactgagga
    11401 gaatagccga aatggaggtt aaccaaagcg tccactcggt ttttgtaaaa tagtttaaat
    11461 aagccatatc cttattcaag cataggcctt tttatctgtc aatagggtgt cgaccttagg
    11521 gaaaaataag ctaatacctg ccatagtgca attggttgtg aggcactaat actagcagat
    11581 aatggtgtta actagaggca aatgagctaa gagtttcctt attggctgct gctaatactc
    11641 cttgttgact ggtttagaag aaaaggacta agagccttag cttggctttg tcagttagtt
    11701 tccttgatga taaggaaaaa ctagattttt taaagcgttt acagtgtcct tttttcttcc
    11761 tataataggg gtataagtga caaaaagaaa ggaaaaagca tatgaagcaa tcaaaacgcc
    11821 gttaccaatt tccagaaggt tttttgtggg gaagctcaac atctggccct caaagtgagg
    11881 ggactgtttc tggagatggg aagggaccta gcaattggga ctactggttt agtctggagc
    11941 cagataagtt tcatcatcag attggtccag aggtaacctc aaccttttac accaactaca
    12001 aaagcgatat tgctctttta aaagagaccg gtcacacagc ttttcggacc tctattcaat
    12061 ggtctcgact gattccagaa ggggttggtc aggttaatcc aaaagctgta gccttttacc
    12121 gagaggtatt tcaggaaatc atggctcagg acattaagct gattgttaac ctctatcatt
    12181 ttgatctgcc ttatgccttg caaggaaaga gaggctggga ggctaaggag acggtctggg
    12241 cttatgagac ctatgctaag acctgttttg agctttttgg tgatttggtg gatacatgga
    12301 ttacctttaa cgaacctatt gttccagtcg aatgcggtta tttggggcat taccactatc
    12361 cttgcaaggt agatgccaag gcagctgttc aagtggctta ccatacccag ttggctagct
    12421 cacttgctat caaggcctgc cacgagttgt atcctaagca taggattagt attgtgctta
    12481 atgtgactcc tgcctatcct agaagtgatc agccagaaga tgtcaaggca gcgagaatcg
    12541 cagagctttt ccagactaaa tccttcctag atccgtctgt cttaggagtg tacccagaag
    12601 agttagtagt tcttttagag gcagctgatt tattgcccca gtatagtgct gatgaattgg
    12661 ctattatcaa aaacaatcct gttgatttct tgggagttaa ttactatcaa cctttgcgtg
    12721 tgcaagcgcc tagcaaaaca agacaagatg gtgaaccaat cacgctagcc tcttattttg
    12781 aaccttatga tatgccaggc aaaaaggtta accctcatcg cggttgggaa atctatgagc
    12841 agggccttta cgacattgct cttaatttaa aagagcatta tggcaatatt gactggttag
    12901 taactgaaaa tggtatggga gtagaaggtg aagaagcctt tttagttgat ggtcagatcc
    12961 aagacgatta ccggattgcc tttatcgaag accatttgat tcaattgcac agggctttag
    13021 aagaaggcgc gaactgtaaa ggctacctcc tgtggacctt tattgattgc tggtcttggt
    13081 taaatgccta taaaaatcgt tatggcttgg tagccttgga tttagagact caaaaacgaa
    13141 cccttaaaaa atctggccac tggtttaaga ccctgagtca gacaaatggt tttgataaat
    13201 aggagcgtat gatggtcacc ttaggatttt ccctttaccc tgagcggcat ggttttgcta
    13261 agagtaaggc ttatattgat ttactgcact gctatggagc caagcgcttg tttatgagcc
    13321 tcttacagtt ggcgccaaat gatcccaaga cctttaagtt ttatgcggat ctgattgctt
    13381 atgccaattg cttgggcatt cgggtcattg cagacgttag ccctgctttt atcaagcagg
    13441 ctggttggtc agatcaggtt attgaagagg ctcatgcttt tggcttagca ggcttgcgtt
    13501 tagatgaggc cttgccttta gaggatattg ttaggctaac gaaaaactct tttgggctta
    13561 agattgaact caatatgagt actgacaaga gtttattgac agccttgcta aaggcagctc
    13621 ctgatcggag taacctcatt ggttgtcata atttttaccc gcacgccttt accggcctgt
    13681 cactggagca ttttaaggaa atgtcccatt tttaccacga gcatgggatt gcaacggctg
    13741 cttttatcac agcccaatca gcaaaggaag gcccttggcc gctgtcagag ggcttaccga
    13801 ctgttgaggc tcatcggcaa ttgccaattg acgtgcaggt ggaactgatg aaggcgacag
    13861 gaactattga tactgtcatt ttgtccaatc aattcatcac tgaagatgaa ctcgttcagt
    13921 gccgtcaagc cttggataga tcagtcatgt ctattaaggt caagcctctg gttgatttga
    13981 cggacataga ggagaagatt atctgttacc cacattgtta tcggggagat gtatcagatt
    14041 atgtgattcg ctcaaccatg ccgcgtgagg tatatgctca agaagcaatt gctccaagag
    14101 agcagcccaa gcaggttaag cgaggcagta ttatcattga taatgaccgt tacaacaggt
    14161 acaagggaga attgcaaatt gcactcaaag cctttaccct tagctcaaag gccaatgtgg
    14221 tcgccaacat taaagaggat tacctaagcc tattagacga gttgaagccc tggcaggagt
    14281 tttcattggt gattgagact gactagtctg gcttcacaat cgatacggaa aatgatggtc
    14341 acttttttca ggaaacattt gctaaactaa gagagtaaag aaagcgtttt ctaaaagacg
    14401 aaggaggaat gatgctatca aaaaaagaaa tggctatagt agcatttcta atcagccaaa
    14461 aagggcagtt tgtctctagt gctaccttgg ctaaggctat tggcatgagt gatcgcacag
    14521 tcagaaaata cctaaaggag ctgattagca gccttcctag taagggagcg cacatcattt
    14581 ccaagcaagg tcagggctac tgtttagaga ttgatcattc tatggcgttt gagatctttt
    14641 ggcaggaaag cttggcctct aaaaagcgct tggctgatgt gactcaggtg gaagaaacag
    14701 ttgatcggga gcattatttg ctaaataaat tcttctttga agagcccgtt tgggattttg
    14761 aagagctctg ccaagaattg tatattagtc ggacgaccct aaaccatgtt ttagcggtta
    14821 ttagagaccg tattaggcct tatcagctac agcttgatgt gagtcatcag cgcgttcagg
    14881 tgacaggtaa ggaagaggct attaggcatt ttatcatgga ttattttttt gctaccagct
    14941 ttgatgactc catgtacgcc atagtagaca atacctttct tgatcatatc aagtttgctg
    15001 atatcacaat aattgtttta gatgaatgtc gagatgccaa actaaagctt tctgattttg
    15061 tcatgcacaa tttggttttg cacattgccc taatggttca gcgtattcgg tctggctatc
    15121 cgttagcatt tttttccatt ccagcagcta ttcgccaatc agacgagtat caagtggctc
    15181 tacgtatttt atatcgagta gaagaagtga tgggcattcg ttttcctaaa gaagaagcta
    15241 actatattgc tttacacctc aaggttaagc attccgttga tggcagccca caggacaata
    15301 aggccgatga cttgctgaga agtcatttaa aagcaggtat tgtcaaggct agtcagctga
    15361 caggtatgtc tttggaggct gatagcagct tgcttcaagg cctattggcc catatgaagc
    15421 ctttagccac aaggcttgaa aatcatattc agctgaccaa tcccttaact gaggagatta
    15481 aaagcaaata cccagaggct tttgccctga ctaagcaagc ttttgagaat attcctgagc
    15541 ttcaggctta tgacctgtct gatgacgaat gggcttacat tagcttgcat atcatggcag
    15601 ctattgagcg ctattccaat cgtcacaaac tgagggtgct tgtggtttgt gccacaggct
    15661 atggcagtgc catgatgctg aaaaatcgct tggaaaagga atttgaaggt cgctttcaga
    15721 ttgtagatgt tatcagctac tatgaaataa cacaggaacg actgcaaacg gttgatgtga
    15781 ttatttcttc tatcagcctt gctaatgtca tgtttttaac gccagtcatt actgtcagtg
    15841 tctttttatc tgatcaagac atcaaagcca ttcgccaatt tatcggggag caggagggaa
    15901 taagaagaga agctgcgtcg tcatcgcaga tgagcttgga aaaagcagag cagattctaa
    15961 aaggtgtctt tagtcctaag cgttttcttt atgtgaaaga aaaactatca aagaaggcct
    16021 tgctgttaaa gatgattgct tgtcttgacg aagcaatgga tgaagccttt gttgaggcct
    16081 tttatcacca aatcgtgttg agggaaaatt atagctcaat tgtttttggt gaggtgcttg
    16141 cctttccaca cccggctaat cccatgacct attctgaaca ggtggtggtg gctgtctgtc
    16201 aagagcctat tgactgggac gagagtcatc gggctgttca ctttatcttt ttgttgtcac
    16261 cgtccaaggg acgtaacagc tatttaaaat atatctcacc gagcttggtg tcttttgtca
    16321 atcaagcaga gcttcagcag gctttattag aagaaccaag ctatgcacaa ttcatcacat
    16381 tatttacccc actcatcact gaataaaagg agaagtatta tgaaaaccat tatgttagtt
    16441 tgtaatgccg gcatgtcaac cagtatgctg gtgactaaaa tgcaaaaagc cgctcaagcg
    16501 cgtggcatcg aggttgagat ttgggcagtt cctgtgagcg aagctgacaa tgaggttgct
    16561 gctaaaacca ttgatgtcct catgttaggg ccgcaggtca aattcttact aaaggacttt
    16621 aagaccaaat ttgaaccggc aattaaggta gatgtcatta acatggctga ctatggcctc
    16681 atgaatggtg acaaggtgct tgaaacagcc ctaacaatga tggaggaaga ggtatgacac
    16741 aatcatcaaa cctagaggcc attatgggat taatcatgta tggcggtgag gccaagggca
    16801 aggctgtaga agctattcat gcagctagag atggtcaatt tgaaaaggct cagcacttgc
    16861 ttcaagaggc tacacattct ttaaatgttg cccatagatc acaaaccaat ttgctatctc
    16921 aggaagcagc tggagatcag gttgatttgt ctttattgct ggtgcatggt caggatcata
    16981 tgatgacagc cttagccttt attgatttgg ccaaggaatt ggtcgctgtt tatgacaaaa
    17041 tatcaagaat ccaaagaggt gagctatgat gatgattaca gcagaaggag atgtctctgt
    17101 cactcaatgc ttcaaggcta tactaagctc tctccaagag gattatcatg aaaacaccct
    17161 gagacggctg ccaccagctg aattaaaagc agggctaagc tacataaagc attatggcaa
    17221 aagcaaggag cataacgtta gagtgctgat cacagcctta gaagctccgc acttatatgc
    17281 tgcttgcttt agctctaatc atgggctaaa aacattaagc taccgcttag aagctctggg
    17341 agagaagcgt accaaaataa cctattgcta cgactatcag ccacttgatg tctttcaaaa
    17401 agccaatcag ctgatcattg ggaagctttt taagaagagc ttcaaacggc aatcacaagc
    17461 ccaattggca gcccttatcc aatatgctaa gcagctaagc taggggaaga tttgagtaca
    17521 gattatctgg ctgattatag ggcttatcat actaaaaaat agaaacagga gaaaattatg
    17581 tcacattttt cggataagtt tatggagatt tcaggaaaga tgggatccca gcggcatttg
    17641 gttgccattc gtgattcctt tatttcgcta atgcccatca cgatggcggg ctctgttgcc
    17701 gtcttgctga atgttttctt gcgtgatatt ccaaacaata tgggctggac tggttttgca
    17761 gcagccatgc agcccattat tgacatcaat ggttatgtgt attttgggac aattggtatc
    17821 atggcactct tttttgcctt tgcttttggg tatcatttag ctcttatgca caaggtgaat
    17881 cctttggctg gaggtttaat ctcctttgct tcctttgtcg ccacccttcc tcaaagctta
    17941 accatttcca caccacttga aggggcgtca gcaagtttat tagcaggctt aaaggatatg
    18001 ggactatcag tggtcactgc aaatggagcc cgagttttag aaacaagcca gtggggagca
    18061 attgccctca aatatgctgg agcaacaggt ctttttacag cattgatcat tggcttttta
    18121 tctagctttg tttatgcgac tttgaccaaa cgtaacctga ccatcaaatt gccagataat
    18181 gtgccacctg cggttaataa ggcttttgcg gctattattc cagggacagt cgcgatttat
    18241 gtgtcagcga tcgtagctta ccttattttt gccctcacag gctcgtctct aagtgatatg
    18301 atttcgacct atatccaatt gcctttgttg gggctgtctc aagggcttgg ctctgttatc
    18361 ctgttaacct tcttggttca attgctctgg ttctttggtt tgcatggtca caatgtctta
    18421 gcacccgtgc ttgatggtgt gtacttagtg gctctaacag aaaatacagc tgcctataat
    18481 accagtcaga gcgttgctaa tctgccttat ctctggacga gaggctcctt tgatgcctat
    18541 gcacaaatgg gtggttcagg tgttactctg gctctgatta ttgctatctt tattttctca
    18601 aaacgtgagg agcacaagac cattgccaaa ttatcagcac cgatgggcgt gtttaacatc
    18661 aatgagccaa ttacctttgg tatgcctatt gtcttgaacc caacctttgc tatcccatgg
    18721 ctaatcgtac caccaatttg tgctagcatt gcttatgctg ccacagcaat aggcttgatc
    18781 cctcccgttt tcttgccagt tccttggatt acgccagttg gactttacgc ttacttggct
    18841 actggaggta gtgttatggc aggtctggtt tccttgttta acctctttgt tgcctttctt
    18901 atctgggcac catttgtcat gtcagctaat aaagaaaaag cgagtgacct ttcatgacag
    18961 caaaaaacgg agcaagcttt ttaatggcta taggattttt ccttattgcc attagtccaa
    19021 tggttggcaa caaataccta catatcgtga caggactagc ttttgttggc ttagggtatt
    19081 atctcactaa gcgcaagcgt ccttagtcaa tgcgagcagc tagcccctat gaaaagacaa
    19141 acctaagggc tagccttgat tttctatctt ggttatcgca tttaaaagca agcaaaaaag
    19201 caagggtaga tgcttacctt tgcttttttt attttttgac ctttaataga atatcttgct
    19261 acttaaacat ttaagacctt atctaaaaat tcaattaagc gtgggtgctt agggtgatca
    19321 aagatttcct ctggagtacc gtcctctagg aattggccgc cgtctgtaaa gatcacacga
    19381 ttagccactt gacgagcaaa gcccatttca tgtgtcacaa tcagcatggt catgccctgc
    19441 tctgctaggt ctttcataac gtttaagacg tctccaacca tctcagggtc aagagcagag
    19501 gtaggctcat caaagagcat gatatcaggg ttcatggcaa gacttcttgc aattgcaaca
    19561 cgctgctttt gaccacctga tagacttcct gggaaagcgt cagccttatc agctagaccg
    19621 accttctcta gaagagcaag tcccttttcc ttagccgcct cctttgagac ctttccaagc
    19681 tcaactggtg caaaggtaat gttatcaagg actgtcatat gtggaaagag attgaagtgc
    19741 tgaaacacca tgccgatatt ttcacgagcc ttatcaatat tggtattagg atctgaaagt
    19801 tcaaagccat caaccacaac cttaccacta gtaatggatt caaggagatt gagggtgcgc
    19861 aggaaggttg attttccaga gccagatggc ccgataatac aaacgacatc accctcgtaa
    19921 aatttagcat taatgccttt taagacctca ttttgcccat aggatttgtg taaatcttga
    19981 acatcaattt ttaattctgc cattagttaa gcctcttttc taaacgtttt gcaagccttg
    20041 ttaagagtgt aatcataatc aagtagataa ctgctaggat agcatacatg cggaaggatt
    20101 gatagtttct agcgataatg attttccctg tttggaagag ctccactaaa ccgatcgctg
    20161 agactatggt cgtatccttc aaggaaatga caaactgatt gatgaagttt ggcagcatta
    20221 gcttaatggc ctgaggaagg ataatccttc gcattgttgt gtgatatgac aagcccaagc
    20281 tgcgactagc ctccatttga cctgccggca cagcctcgat acccccacga acaatttcgg
    20341 caatataggc tccaccattt agcgaaagtg caatagtagc agctacaaaa tcgttaatcg
    20401 gtgattgatg cccagtcatg ctttcaatga ggtttggcac tccccagaag ataaaggcag
    20461 caacaatcat caaggggata ccacgcacca catcaacaaa gatagtagaa gccatgcgca
    20521 ggttctttga tggggataca gccatcattc caaaaacaat accaataacc aaagcaatgg
    20581 caaaggagat gagtgtcaga ccaagggttg ttccaagccc agccaataat tgcttgtagt
    20641 tattagctaa aagtccataa atagttgact catcggctgt tttgacagat gcctctgaat
    20701 caaggtatct gctgatgatg gcgtcgtatt ttcctgatgc tttaagagca gccaaaccgt
    20761 tgttaaacat ttcgatgagc tcagggttgg ctcctttttt aacagcaaaa ccatactcac
    20821 cagaaggctc tcccttgata ggaatatcaa gcttgtggcc tcgctgaata gcgtacctta
    20881 aaatagcttc atcatccata agcccgtcaa tagaaccaga atttaagcta tcgtacattg
    20941 aggaggcctc atcaaaggct tttagacggt aaccataaat atccttgttg ctttcaagga
    21001 aatcatagga ggctgttcct tttttggcac cgactatttt acccttgagg tccttgtatg
    21061 atttgataga gcttccggat ttgaccccaa ggcgaatgtt tgatgtgtag taggaatctg
    21121 aaaaatcaaa aatctcacga cgtgcaggtg tgatagacat acctgcaata acagcgtcag
    21181 cctgaccagc ttgaacagca tttaaagcag cgtcaaagcc aggattgctg atctcaatgg
    21241 taaagccttg ctgcttagca attgccttga tgaggtccat atcaataccg acatattctc
    21301 cgctgccaat ttgaaattca aagggagcaa aggaggagtc agccacgatt ttataaaccg
    21361 gctttaaagg agtggcctta gcagaggcat cgccagtagc cttgcctgct gtgaccttgt
    21421 cattgctgcc aagccatttt gtcatgatag cttgataggt tccatcagcc ttcatagcgc
    21481 ctaaggcttc attgaagtcg tcaatgagat aatcatagcc gctgcctttt ttgacagcaa
    21541 agccaaagct tccaatagcc tctcccttca tgttgatcgc aagatcctgc ttttggttaa
    21601 tggcatattg aatgacaggc tcgtcgtcca taacagcgtc aatagagcct gttgcaagac
    21661 tgttgtacat caggtcacct gtgtcaaatg ttttaacagt ataaccatac gattttttgt
    21721 atttatctaa gaaggcttga gcagctgttc catttttaac accgactgtt tttcctttta
    21781 gctcgctata tttcttaata gggttagcct ttcttgtagc aataacaatt tttgtatcgt
    21841 aatagggatc tgaaaaatgg aagacctttt gacgagcagc agtgatggtg gtgcctgcca
    21901 taagggcgtc agcttgacca gactgaatgg cattgacagc agcatcaaag ccagggaatg
    21961 tcatattgat attccaaccc tttcgctttg ctacttcatt gatgatgtca acatcaatcc
    22021 ccttatacac ctgatctgaa tccttgaatt caaacggtgc ataagcagta tcagaaacaa
    22081 tatcaattgt ctctgcactt gcaatcccag cagtcatcaa aacaactgac agcattgcaa
    22141 gcatccatgc ttttaatgtg tttttcatac tagtctcctt aataaaaata aaaaatatgc
    22201 ctaattatag cagatttttt tcaaacaagc aaatcatctc ttctttttat gtcataaaac
    22261 ctaacataaa caactaaaat agtcaaaaag ctttgataga gtctttaagt ccttaactat
    22321 gttacaatag ataagagata agatattgag gaccaataaa tgattgataa acgtgatttt
    22381 aaagcattta agctcgtgtc aaaatatgcc ccctcaggag atcagccgca ggcgattgag
    22441 accttggttg ataacattga aggtggtgaa aaagcgcaga ttttactagg agcaacagga
    22501 acagggaaaa cctataccat gagtcaggtg atcagcaagg tcaacaagcc aacgttagtg
    22561 gttgctcata acaaaacctt ggccggtcaa ttgtacggtg agtttaaaga gttctttcct
    22621 gaaaatgctg tcgagtactt tgtatcctac tatgactatt atcagcctga ggcctatgtt
    22681 ccttctagtg atacctatat tgaaaaagac agctctgtta atgatgagat tgacaagctg
    22741 cgccattcgg ccacctcatc gcttttagag cgtaatgatg tgattgttgt ggcttcggtt
    22801 tcttgtattt acggattggg ctcaccaaag gaatatgctg attcagctgt tagcctgcgt
    22861 cctgggcagg agatatccag ggatcagttg ctcaatgccc ttgtagacat tcagtttgaa
    22921 cgcaatgaca ttgattttca acgtggacgc tttcgtgtgc gtggtgatgt ggttgaagta
    22981 tttccagcct caagagatga gcatgccttt cggattgagt ttttcggtga tgagattgat
    23041 cggattcgtg aaattgaaag cctaacgggt aaagtattag gtgatgctga tcatttagtg
    23101 ctttttccgg ccactcactt tgtgaccaat gatgagcaca tggagcagtc tattagcaag
    23161 attcaggcag aattagcaga ccagcttaag ctatttgaag cagaaggcaa attgctagag
    23221 gctcagcgcc tgcgtcaaag gacagaatac gatattgaaa tgctacgtga aatgggctac
    23281 accaatgggg ttgaaaatta ctcacgtcac atggacgggc gttcggcagg agagcctcct
    23341 tataccctgt tagatttctt tccggatgat tttcttatca tgattgacga gagtcacatg
    23401 accatgggac aaattaaagg catgtacaat ggagacaagg ctagaaagca aatgcttgtg
    23461 gattatggct ttcgtcttcc gtctgcctta gacaatcgtc cgcttcgtcg ggaggagttt
    23521 gaaagtcatg tgcaccagat tgtctatgtc tcagcaacgc ctggagatta cgagatggag
    23581 cagactgata cgattgtgga gcagattatc agaccgacag gtctgcttga tccggaggtt
    23641 gaagtccggc caagcatggg acaaatggac gacttgcttg gcgagattaa cctgagggtt
    23701 gaacgaggtg agcgcacctt tatcacaacc ttaaccaaga aaatggcgga ggatttgacc
    23761 gactacctca aggaaatggg tgtcaaggta aaatacatgc atagcgacat caagacatta
    23821 gagcgtacag aaattattcg cgaccttcgt ttaggcgttt ttgatgtctt gattggtatc
    23881 aatctgctgc gtgaaggtat tgatgttccg gaggttagcc ttgttgctat tcttgatgcg
    23941 gataaggaag gcttcctaag aaatgaacga ggtttgattc agacgattgg tcgagctgcc
    24001 agaaatgctg atggtcatgt gattatgtat gctgatcgta tgacggattc catgcagcgc
    24061 gctatagatg aaactgctcg tcgtcgtgcc atacagatgg catataatga agagcatggg
    24121 attattccgc aaaccattaa aaaagatatt cgtgatttaa tcagtatttc cagagcagtt
    24181 gaagcaaaag caacagaagc agagacaaat tatgagtcaa tgacgcggtc tgaaagacaa
    24241 gaagctatta agcaattgca aaaaaacatg caggaagcag cagagctgct ggattttgaa
    24301 ttagcagcac agcttcgtga cctgatctta gagttaaaag caatggatta agacctgata
    24361 agctaagtct ggctgtataa gctaggcttt ttatctgctt ttgagtttgt cctttaggtc
    24421 tgtcttatga tctttggtac cagataaatg agtgatatct tgagcttgat ctacgcaaga
    24481 gctagtgcag ccactagctt cagactactt taatgattta atgaaagatt gattttgata
    24541 agacaattct gatataatgt aaagtagttg gcaaaaatag aaacattaaa taaattttct
    24601 ttttaataat ttaactttta ccttgtcaac aaggctattt tcggatagaa tttcttagta
    24661 cattatttca ctaatacaag aaggtaagta tgttaaaaaa caagtcaaga ctgcgagcta
    24721 ttttcgtttt tgttgggaag atagcgttgt tttacgtgat tttgatgctg ctcgtttatt
    24781 tttttggtta cctagggcat ggtcaaagta attttattta taatgaattt taggagattg
    24841 tctgatggtt aacgatatga ttgaaacaat tgagtatttt gcacaagcac aaccggattt
    24901 tccagtttat gattgcttgg gagagcgccg tagctatggg cagctaaagg aggactcaga
    24961 tagtattgca gcccttattg agagcttaaa gctaggtgaa aaatcacctg ttttagtttt
    25021 tggggctcaa agctatgaca tgctggcttc ctttgtcgcc ttgacaaaga caggtcatgc
    25081 ttacattcct gttgatgttc attcggcgcc agagcgtgtc ttgtctatta ttgagattgc
    25141 tcagccaagt cttatcattg ctattgagga gctgccggtt agtattgatg cgattagggt
    25201 ggttagctta gcagagatag aggcagctaa agcagccaag gcagccttta ccatgaccag
    25261 tcctgtcaag ggagatgaca attattatat tatcttcacc tctggaacga caggacagcc
    25321 aaagggagtg caaatttcgc atgccaatct tttaagcttt accaattgga tgattgagga
    25381 tgctgagttt gctattcctg agagaccaca gatgctggct cagcctcctt attcctttga
    25441 tttgtcggtg atgtattggg cgccgacctt agctttaggt gggacattgt ttgctttacc
    25501 caaggaaatg gtttcagatt ttaagcgctt gtttagcaca attgcggagc tgccgatagg
    25561 gatttggacc tcaacaccgt cctttgccga catggcaatg cttaatgatg atttttgtca
    25621 ggagaagatg ccaaggctga cccactttta ttttgatggg gaggagctga cagtatcaac
    25681 tgcaagaaag ctatttgaac gctttccaga cgcacgcatt atcaatgcct atggtccaac
    25741 agaggcaacg gtggcgttat cagcgatttc aatcactaaa gatatgatag agacttacac
    25801 acgcttgccg ataggctatc caaagccgga ttcgcctact tatatcattg atgaagctgg
    25861 caatgctctg gagccggggc aacagggaga gattattgta acgggtccag cagtttctaa
    25921 gggttatctc aacaatcctg aaaagacagc tgaagccttc tttaccttta atggcatgcc
    25981 tgcttatcat acgggagatt taggatcatt tactgaggac aatgtgttac tttatggtgg
    26041 acgattagac tttcaaatca aatatgcagg ttaccgcatc gaattagaag atgtgtcgca
    26101 gcagctaaac caatcaccgc tggttgaatc agcagtagca gtaccaaggt ataacaaaga
    26161 gcataaggtc caaaatctct tagcttatgt tgtcttgaag gacggggtga gggagcaatt
    26221 tgcgagagat ttggatatta ccaaagccat taaagcctct gttaaggatc atatgatggc
    26281 ctatatgatg ccgtctaagt ttatttatcg tgaaaagctc ccattgacac caaatggcaa
    26341 aatcgatatc aaattcttga ttaacgaggt taatcatcaa tgacgacctt gtttcatcac
    26401 ataccttata tggagcctta tggcaatccg atttattttg tctacctcat cattgctttt
    26461 cttccagtta ttattgggat ctttaagcaa aggcgttttt cgacgtatga aagctttgtc
    26521 agcctgatct ttattttgct catgtttggt ggagagcact atcagcaatt gcttgccttt
    26581 ttagcctatc taatttggca aaccatcagt gttttggctt acaagcacta tcgtcaaaag
    26641 gcaaatgcag cgtgggtttt ctatcttagc attttagcca gtctatttcc tttgatttgt
    26701 gtgaaggtaa gcctcagtct aacgaggtct ttctttagct tcttaggtat ttcctattta
    26761 actttcaaaa gcgttgggat gatcattgaa atgcgtgatg gggttttgac agattttagt
    26821 ctaaaggatt ttctacgctt tatgattttc tttccgactt tttcaagcgg gccgattgat
    26881 cgcttcagaa ggtttcaaga ggcttacacc aagcttccta gtcgtgatgt ttaccttgat
    26941 atgctcaata aggctgtcat gtatctcatg ctgggctttc tgtacaagca tattatctct
    27001 tattgcttgg gtgggctgct attgcccctt gctgaaaata aggctctgac tgtaggtggc
    27061 tactttaata aagagacgat ctatgtcatg tacctttatg ggcttaatct cttttttgat
    27121 tttgctggct actcgatgtt tgcgattggg ttgtcttatt tactggggat taagacacct
    27181 gaaaatttca ataagccctt cttatcacca aatttaaaag agttttggaa cagatggcat
    27241 atgagcctat cattttggtt tagggatttt gtttttatgc gattggtcca tctattgatc
    27301 aagcacaaga cctttaagaa tcgaaatgtg acttcgggct ttgcttacct gatcaacatg
    27361 ctggtgatgg gactttggca tggcttgacg tggtattata ttgcttacgg tctgtttcat
    27421 ggtattggct tgattgtaaa cgacgcttgg cttcgtaaga aaaaggaaat caatcgtcgt
    27481 cggaaaaagc aagggcttaa gcctttgttt gagggtaagg tatttcatgc tttatcaatc
    27541 gtggtcactt tccacgttgt cttgttctca cttctgttat tctcaggctt cttaaatgag
    27601 ctttggttta gcagaccgtt acgttaaaaa aggagagtat aaaaatgtct actaaagaaa
    27661 ctgtaattga cttatttgat cgcttgttta tggaagacgt atcagatatg atggacgagg
    27721 atttgtttga tgctggcgtt cttgatagcc taggaacggt tgagctgatt gtagagatcg
    27781 aatctatctt taacattaag gtgccaattt cagagtttgg acgtgaggac tggaacactg
    27841 ccaataaaat tattcagggc atagaggaat tgcagcatgc ttaaacggct ttggttaatc
    27901 ctaggtcctc taatcatcgc ttttggcttg gtttgtctta ccatattcag ctttcctact
    27961 aagcttagct attcattgcg ccaggaaaag tcaaatgcag tggcaatcaa tgatagctcc
    28021 tttaaaaacg gcttgattaa aaggcaggcc ttgtcagatc ctaactactg ttttgttccg
    28081 ttttttggct ctagcgaatg gagtcgcatg gatagcatgc acccatcagt gcttgcagaa
    28141 cgctacaagc gctcctacag accgttttta attgggaaaa gaggctctgc ttccttatca
    28201 caatattacg gcatgcagca gatttcacag gaaataactg gaaaaaaggc agtctttgtc
    28261 gtgtccccac aatggtttac cccccaaggc attgatcctg gtgcggttca attgtatcta
    28321 tctaatagtc aggtgattga tttcctctta aaagcaaagg ctagtcataa ggaatcacaa
    28381 tttgccgcta aaagaatgct ggacattaat ccgggagttg ctaaatcaga gcttttaagg
    28441 aaaattagtc aaggcaaggc cttgagtaga tgggacattc gtctgctcaa atggcagcag
    28501 gagctgtcct taagagagga gtccttgttt agcttccttg gtcgttcaac aaactatgag
    28561 gataggattt tgcctcgtgt taaagggttg cctaaaacct tttcttatga gcgcttgagc
    28621 gagctagcag ccagacgggc taaggaagga acttcaaata atcgctttgg catcaaaaat
    28681 gctttttatt ctaagcgaat tgcaccgcaa tttcctcttt ataagaattt tcagtgccgt
    28741 aataattaca ctgtgtcacc tgagtacaat gattttcagc tggtattgtc agaatttgca
    28801 aaacgtaaaa cagaggtgct tttcgttatt acacctgtta atcaagcgtg ggcaaattat
    28861 acaggcttaa accagaggag gtatcaaaag gctgtcagaa aaataaagca tcagttaacc
    28921 tcgcagggct ttactcgcat tgctgatttt tccagaaatg gcggagacaa gtattttatg
    28981 gaggatacca ttcaccttgg ctggaatggc tggctagcct ttgacaagga ggttgttcct
    29041 ttcttagagg atcaaacacc accatctgaa taccaactgg atccttactt cctatcaaag
    29101 gactgggcag atagaacagc aggattttag ggtcaataga ccattagaaa atgaggatta
    29161 gaattgttaa tgagtatcat cgtcatattg cttattttag ccattgctgt tttagtgatt
    29221 gagtatggtc aaaagcggtc cttttctagc tggctgcttg aaaagatgtt tgattatcgt
    29281 aagtataagc tctctaaaaa ggctgatgac tatgaaggaa ttgagacgca aagacgtcgt
    29341 cgcattccct accacttgga taatccagag gcggtattgg ggattcccac cacagaatat
    29401 acgattgatg gcatgcaggt ttttgtgatc aatgaccaag attctcagga tcagccagtg
    29461 atttactatc tttatggtag tgtctatttg cgtcgacctg agacatttca ctttaaaacc
    29521 attaagcatt tgatccattt aaccaatgcc aagctggtgt tcccaaattt tgagaaggcg
    29581 ccttatgtca cctataagga gatttaccca aagcttgcta aaacttatca ggagctttgt
    29641 ctagccaatg gcgctgccaa ggttagcatt attggtgact cctcaggtgg tggcatggcc
    29701 ttagccttgg cgcaatacct aagagatacc caaactgcac cacagccaaa gcaattaatc
    29761 ctgttatctc cttggttaga tgttagcttt gctaatcagg attataagca ttttgaagca
    29821 gtagaggctt atttagatgc taggcggctt cgagacattg gtgaattgtg ggcaggcagt
    29881 ccagaagaaa tgcggtctcc gtatgtcagc ccattatatg gcgattatca tgacctgcca
    29941 aagattgtca cttttgtcgg gacaaaagag attttttacc cagatattat gaccctgcat
    30001 gagcgcttga tggagcaagg gcacttaaat cagctcgtta ttgctgagca gatgattcat
    30061 gcttatgcga tcttcccgat acgagaggca aggcaggcgc gcaagcagat tgccgagctg
    30121 attttaaaga aggagtgatt gttgctatag gagtcagtta gccttgcttg tctgatgagg
    30181 cttgggcttg agatttctag agaagcttta aggcctttac ttgggctgtt aatgctcatt
    30241 aaagaggatt ataggcttta tactagggct taggattgct gttttgctat tcaataatat
    30301 tagtttagac ttgattgagg aaaggctagt tttagttatg gtcctcaatc tttttttgat
    30361 ggtaaacatg tcaagacagt ttacttgcta gggtaataat cctgtgctca tttcatgagt
    30421 ggctattttt atcctaagct tggtggtgga aaaatcagat taaaaaatat gaaatttgct
    30481 attgacagct gtaagcgatt gcattataat aaacttaact taaacgttta agttaagttg
    30541 aataagctga tttgatcatg cactgcctaa atgcaatcaa taatctcaaa gcatttggtg
    30601 tagtctagta atcaatgagg cagtttatta cggttataca atatttattt agttcatccc
    30661 tttaggaggt aaatagctat ggcgtgggat tggaaaaaag caggtgttgt tggagtagtg
    30721 tcattggctt cgatcatggt attaagtgct tgtagcggag gacatcaaaa agaggctaag
    30781 caaaaagacg acaataccat tgtagtttca gttgatgagg gctatgcaga ctacatcaaa
    30841 gagattaaga cagcctttga aaaggacaat aaggtcaagg tcaaggtcaa aaaggaaggt
    30901 atgattgata cgctagataa gctatctact gatggaccga caggtgcttc accagatgtc
    30961 tttttagcac catatgaccg ggttggtggg cttggctctg aagggcaaat tgctgaggtg
    31021 agcttaggca atgctgacca gtttgatgac actgttaaaa agctagtcac cataaatgga
    31081 aaggtttatg gggcaccaga tgttattgag accttagtga tgtattataa caaggatttg
    31141 gtatcagagg ctccgaaaac ctttactgac attgaagagc taaataagga tcctaagttt
    31201 gcctttgctt ctgaagacgg taagtctgta ggctttcttg ctaagtggac agacttctat
    31261 tatggctatg gcttgattgc aggctatggg gcttatgtat ttggagataa gggaactgat
    31321 ccaaaggatt taggtattgg taatgctggt gccattgaag gcttagacta tgctaagaaa
    31381 tggtatagcg tatggcctca aggcatgcag gatactcaaa aggctggaga ttttattaca
    31441 gagcaattca cctctaaaaa ggctggtgtg attattgatg gaccttgggc tgctgcctca
    31501 tttaaggagg ctggtgtaaa ctttggagtg gcacaaattc caagcttacc taatggcggt
    31561 agctatcaag cctttggtgg tggtaaagca tgggtgattt caaattattc taagaataaa
    31621 aagctggcac agcaattcct tgattatgtg acaaatgaga aaaaccaaaa agccttttat
    31681 gataagacac aagagatccc tgccaatcta gctgctcgca gctatgctgc agaacaagga
    31741 aatgaattga caaaggcggt tattgggcaa ttctcaaatg ctcagccaat gccaaatatt
    31801 ccagaaatgg cagaagtttg gggaccaggt gcgaacatgt tctttgaggt agcagcaggc
    31861 aagaagactc ctgccaaggc tgctaaggaa gcagctaaaa ccattcaaga ggctattgca
    31921 caaaaataca ctgaataaca taaaaaggga ggctgggata aaggtatcct agtctccatc
    31981 ttgttaccta tagtatcaga gtgggcgatg aggagataat aataaaaagt agtagtgact
    32041 agcttgtctt gtttcccatc ttgtcctaat aagagtatct gataagactg atgaacctag
    32101 ggaggaaaaa atgaacacag ccggaatact gcatattcca gattctagat attgctttgc
    32161 cttatcaaca aaggagcttg tgattcggtt gagggttgca aaggaggata acgatatagc
    32221 ggtgacgctg gtttatggac ctaagtatca ttatcatgag tatcaaaaag aactggcgat
    32281 gtatgctgct tataccgatc atacccatac ctattatgaa atcaccttaa gtcttgatga
    32341 tgttagattg gcctatattt ttaagcttga gcaatctggt cacacctatt actttagtga
    32401 ggatggcttg accacaagct atgatttttc aaatggcttt tacaactttt ttcaaatgcc
    32461 ttatattaat gctgtagacg ttcatcagac tgtcccttgg gtgcacaatg ctgtttttta
    32521 tcagatcttt gttgatcgct ttcatcgtgg tgactttgaa aaggacgata gctatattaa
    32581 tatggcttgg ctggataggc caactcctaa tagctttgcc ggaggggatt tgaaggggat
    32641 tacagataag ctggaatacc ttgaggatct tggtattaat gtcatttact tgacaccgat
    32701 tttcaaatcc atcagtaatc acaaatatga tattagtgac tactatgcta ttgacccgat
    32761 gtttgggaca tcgcttgatc tccagcaact aataaacgag gcccaccaaa gagggattag
    32821 aattatttta gatgctgttt tcaatcatgc tagcagtgat tgcgagccat ttcaggacgt
    32881 tttggcacat ggtagtgctt cttcattttt tgattggttt atgattcaag gagatcatcc
    32941 ttctgtagag ctagctaatt acgaaacctt cgctgattgt cactacatgc ctaagtggaa
    33001 tacctcgcat caggctgttc aggattattt gattgagatt ggtctttatt ggatcacaga
    33061 gtatcatatt gatggctggc gattagatgt ttctgatgag gtatcgcatg atttttggag
    33121 acgctttcga aaggctgtta aggcagtcaa atcagatgcg atacttattg gagagaattg
    33181 gcatgatgct tatccctacc ttcaaggaga ccagtatgat ggtattatga attacgcctt
    33241 taccaaggct tgtctcgatt attttgcatt tgatgcgatt agctcacagg aaatggctga
    33301 aagattgtcg catattttaa tgagaaatac ttggcaggtc aaccagatga atctgaattt
    33361 actggattcc catgatacgc atcgcttctt gactcaggtg aatggctcta aggacaaatt
    33421 attggctggc ttagcccttt tagttacctt tatgggcata ccatgtattt actatggaac
    33481 agagcttgcg atggagggag gttatgatcc tgactctaga cgtagcttta attgggacag
    33541 cagcacttgg gatatgagct tttggaatca ggttaaggac attatcagcc tgcgtcgtca
    33601 tgcggttatc caatttggaa gcatttcgat aacctcccat gatgactgcc tttgcgtaaa
    33661 gcgtgaatta aacggtcaat cgataagatt gctggttaat aatggcgtta agccatatcc
    33721 tattgagaaa ggaggttctg tgcttgtttc taatggtgta gataaagaga catttgagct
    33781 actccagaac gggtttgttg ttagctatta atatggcgtt ttatcaaagg aggttaagga
    33841 tgaagcgtat tactttaaca tgtcgtaaag cattaacagt agctatggca gcggttacct
    33901 tagcaatgtc aactaacagt gtctttgcta ttgaaaatac tgcggtgtct aataaggctg
    33961 atttttctac tgacacgatt tatcaaattg tcaccgatcg ttttcatgat ggtaatgctg
    34021 ctaataatgg aaatacagat gtatttgata aaaatgatcc taaaaaatat catgggggtg
    34081 attgggcagg tatcattaag aaactagaag atggctactt aaccaattta ggggtatcag
    34141 ctatctggat ttcatcacca gttgaaaaca ttgataccat tgacccttca aatggcagtg
    34201 cagcctatca tggctactgg gcaaaggatt ttttcaaagc aaacagtcac tttggaacaa
    34261 tggaggattt taaaaagctc attcaggtgg cacatggcaa aaacattaaa gtagttattg
    34321 attttgctcc taatcatacc tcaatagcag aatataatgg cttaaccttc cctgaggacg
    34381 gtgctttata taaggacggc cagctggttg gtaaattcag tcatgatgat caaaagattt
    34441 tcaatcatga atcatggact gatttttcaa cttatgaaaa tagcatttat cattccatgt
    34501 atggcttggc agacttgaac aatctgaatc caacagttga cgattatctc aaagaggcta
    34561 ttgataaatg gttagaaatg ggcattgatg gtattcgtgt agatgcggtc aagcatatgt
    34621 cacaaggctg gcaaaaaaat tggttgagtc atatctatga gaagcataat gtattcgcct
    34681 ttggggaatg gtttgctgac ggttctttta atgatccatt gatgactaaa tttgctgata
    34741 ctagcggcat gagcctgctt gattttaggt ttgctaattc tgttaggcgc ctgtattctg
    34801 atttatcagc gaaaatgcaa gatttttaca atatgattgt agctacggaa aaagagtaca
    34861 aggaagtttc agatcaagtg actttcattg ataaccatga tatgacccgc tttgctactc
    34921 tagtcaatca taatcagaca gctgttaatc aagcctatgc tttactgcta acatcgcgtg
    34981 gtgttccgaa tctttattat ggttcagagc agtatgctac aggtgctaac gaccctgaaa
    35041 atcgtggtga tatgccaacc tttgataaga attccactgc ttatcaggtg attagcaaac
    35101 tagcaccact gcgtaagaaa aatcaagccc tggcttatgg tacaacacag cagcgctgga
    35161 ttaatgatca ggtcttggcc tttgaaagaa aatttggaaa tgacgttgct ttagtggctg
    35221 ttaataagga tcaaacaaat ggctacacaa ttagtggcgc taaaacggct ttaccagctg
    35281 gtaagtatgc tgatgaatta ggtggcttac tgggcggaaa ggaattaacg gtatcagctg
    35341 atggtaatgt tgaggcattt gagttaggtg cgggtcaggt tgcagtttgg acctttaaag
    35401 ggcaacatga gacaccgcag ataggagacg tagacgcttc gtttggcgtt gcaggaaata
    35461 ctgtctctat ttcagggcaa ggatttggta gtgctcaagg tcagcttcat tttggtgata
    35521 gcaaagcaga tattgtgtca tgggacgata ccttgattca atttaagata cctgctgtag
    35581 ctgctgggaa ccatgatatt aaggtgacca catctacagg acaaagcagt agcccttaca
    35641 aagcctttga agtgttaaca gataagcaaa ttccagtaag attggtggtc aataatttca
    35701 acactgtatt aggtgagcag ctttatatcg ttggtgatgt ggttgagctt ggggcaaatg
    35761 ataatcataa agctttaggg cctattttta atgcaacaca gtcaattgcg cagtacccaa
    35821 attggttcta tgatgtcaat ctgcctatta acaaaaccat taactgtcat cttgtaaaga
    35881 aggatagttc tggtaaagta ttgtggacta gtccagaaac ctataccatt aaaactgata
    35941 gcaaggctca aaccatttca ttgaaaaaat agttgcgtta tctgtgatgt tatttaatac
    36001 tctatgaagg aggagaacca taaaagggtg atagagagga atgacaaatg cttaagaatg
    36061 aaaaaatgaa gaatccacaa aaagccatgt ggctttcaat aatccctggt ctggggcaac
    36121 tctacaatac tcaaaaggta aaaggcttta ttttgcttct tgtgttttta ggtgagctgc
    36181 tagaggcttt ctttgttggt attccggctc ttgctggctt gtacagcctt ggtagtgtac
    36241 caatggagga tcattcccta ttcttattga ttaagggagc tatgcagctt atcctatttg
    36301 ccttgttttt gatctttcat ttggctgcta tgcgagatgc tagactagtg gcaagggaga
    36361 tcaatgcagg ccatagcatt tcattaacct taaaggagat ggtacaatcc atctatgaaa
    36421 agggctttcc ttatttgctg attattccag cctacttggc catggccttt gccattgttt
    36481 ttccggtgct tgttacttta ttaattgcat ttacaaacta tgattttagg catattcctc
    36541 cctataaatt attagattgg gttggcatta agaattttaa aagcatttta gagcttagca
    36601 cctttaagtc agcctttggc tctgtgctgt catggacctt gatttggacc ttggcggcaa
    36661 cgagtctcca gattgtgata ggaatagcga ctgctattat tgccaaccag tcctttgtga
    36721 agtgcaggcg catttttggg gtgattttct tgctgccttg gggggtgcct gcttttatct
    36781 cgatcatgag ctttggtaat ttctttaatg attctatcgg tgctatgaat gttcaggtct
    36841 taccattttt agaaaagttt gtgccatttg cagattttgg gattatccca tggaagacag
    36901 atcctttttg gacaaaggtt gcggtgatta tggttcaggg ctggctgggc tttccttata
    36961 tttatatttt ggtgtctggt attttacaat caattcctgc tgatttgtat gaggcagcaa
    37021 cggttgatgg tgcaacagcc ctgcagaagt ttcgccaaat taccttgcca atgatctttg
    37081 ctgtcgcagc cccgacctta atctcgcagt atacctttaa ttttaataac ttctccatta
    37141 tttatctctt taataatgga ggtcctggta cagttggcgg tggcgcaggg tcgacagata
    37201 ttttgatttc ttggatttac aagctgacca cacaaacgtc accacagttt tccattgctt
    37261 cagcggtgac cttaatcatt tccttgattg ttatttctgt atcattgata acctttaaaa
    37321 aattcaaagc ctttgacatg gaggatcgct aaatgggtag gaattatttg ccacagtcag
    37381 tgaagaagaa gcgcttgtta gctcagctgt tgacttacag ctatttgcta atcctgtcga
    37441 tcatcatctt atttccaatc ttggtgaccg ttagctcagc ctttaggcca ggaaatacaa
    37501 ctgcctttag ctttcatatt gatgggcctt ggaccttatc aaactttgag acactctttc
    37561 aggacaccta ttacttaaga tggtactgga acacgttagt tgtcgccttt ttcacgatgc
    37621 tgatccaggt gacagtcatt acgctgacag gctatgctta cagccgttat cacttttttg
    37681 ggcgtcaaaa gagtttggtc tttttcttag tggttcagat ggttccgaca atggctgcct
    37741 taacagctta ttttgtgatg gcttggttgt ttaatgctct gaatcactat tggttcctca
    37801 ttctgattta tgttggagga ggcattccga tgaatgcttg gttgatgaag gggtattttg
    37861 atactgtgcc ttatgattta gatgagtcag ctaagctaga tggctctggt cactttagga
    37921 ccttctacca aattgtattt cctctggttc gtcctatggt tgctgttcag gccctatggg
    37981 cctttatggg gccatttggt gactttatgc ttgctaagtt tctcttgcgt gaacaggagc
    38041 attacaccgt agcggtaggt cttcagtcat tcatcactaa cgacgctagg gatcctaagg
    38101 tcacattgtt tgcagccggg gccattttaa ttgcagtgcc aatttcagtg ctattcttct
    38161 ttttacagaa gcattttgtt tcaggcttaa ccaatggtgg aacaaagggt taatttatct
    38221 ttcaaggagc ctttatcatg actaatgatc gatttcctat ttcttacaca accattattt
    38281 tttctcctaa aatgatattt gctcgttgca gtgccttttt gtggtggcag aatgtgattt
    38341 tagtgatctt tctaaatgct ctggtgttaa tgccgatcac gctgcattat gcaagcttga
    38401 agagctatcc cttagagcac atagttagta atggtttaga ctccttgaca gaaaaaacct
    38461 atcatgcctt gacacaaggc actatttggc atgatcgcta tgatggaaaa acagtcctta
    38521 tagaggatac tgatgctgtt gttgctgtat tgccaacacc agaaatagta gaagagctaa
    38581 agaaagatca aagaagccag ctgatattaa cagaaacctc atggatttta agctttcctg
    38641 atggtcaaag gctaactgct aaggttaaag gcaacaagga aaggctaacg cgcttaacct
    38701 ctctagaggc tgtcaaggcc tttgttaatc agcaatggta caatagcaat cgtgccgctg
    38761 tgcttgcctt tttgctgcta gtggctagca gtgtggtcta tctaggagcc ggtttagtga
    38821 tcggaattgg ctcgttatca ctgttattaa caagatctgc tagattattt tcactcaaga
    38881 gctactcaga atgcttgggt ttgctagtga attgctttgg acttcctacg cttttagcag
    38941 tgcttataag tttttgggtg cacaatccta ttgttatcat gaatagtcag gtctttggca
    39001 cactgctcat gctggttcta gtcttttaca aaactcagtt tagagatgag gagcaagcac
    39061 tagcttagcc cttgctgaca tcaaaaaatc cctccc
//
LOCUS       DARYVE010000014        38099 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYVE010000014 DARYVE010000000
VERSION     DARYVE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38099
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(263..394)
                     /locus_tag="TVW25_000658"
     CDS             complement(263..394)
                     /locus_tag="TVW25_000658"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378315.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(1503..3449)
                     /gene="thrS"
                     /locus_tag="TVW25_000659"
     CDS             complement(1503..3449)
                     /gene="thrS"
                     /locus_tag="TVW25_000659"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1378316.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(4040..5374)
                     /locus_tag="TVW25_000660"
     CDS             complement(4040..5374)
                     /locus_tag="TVW25_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1378317.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(5376..6374)
                     /locus_tag="TVW25_000661"
     CDS             complement(5376..6374)
                     /locus_tag="TVW25_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1378318.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(6670..8145)
                     /locus_tag="TVW25_000662"
     CDS             complement(6670..8145)
                     /locus_tag="TVW25_000662"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1378319.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(8215..9216)
                     /gene="ccpA"
                     /locus_tag="TVW25_000663"
     CDS             complement(8215..9216)
                     /gene="ccpA"
                     /locus_tag="TVW25_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1378320.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            9390..10475
                     /locus_tag="TVW25_000664"
     CDS             9390..10475
                     /locus_tag="TVW25_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1378321.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSILPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(10649..12232)
                     /locus_tag="TVW25_000665"
     CDS             complement(10649..12232)
                     /locus_tag="TVW25_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378322.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            12470..13321
                     /locus_tag="TVW25_000666"
     CDS             12470..13321
                     /locus_tag="TVW25_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1378323.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            13582..14250
                     /locus_tag="TVW25_000667"
     CDS             13582..14250
                     /locus_tag="TVW25_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1378324.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            14365..15291
                     /locus_tag="TVW25_000668"
     CDS             14365..15291
                     /locus_tag="TVW25_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1378325.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(15275..15463)
                     /locus_tag="TVW25_000669"
     CDS             complement(15275..15463)
                     /locus_tag="TVW25_000669"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378326.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(15575..16042)
                     /gene="smpB"
                     /locus_tag="TVW25_000670"
     CDS             complement(15575..16042)
                     /gene="smpB"
                     /locus_tag="TVW25_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1378327.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(16045..18369)
                     /gene="rnr"
                     /locus_tag="TVW25_000671"
     CDS             complement(16045..18369)
                     /gene="rnr"
                     /locus_tag="TVW25_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1378328.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(18456..18692)
                     /gene="secG"
                     /locus_tag="TVW25_000672"
     CDS             complement(18456..18692)
                     /gene="secG"
                     /locus_tag="TVW25_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1378329.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(18738..18884)
                     /gene="rpmG"
                     /locus_tag="TVW25_000673"
     CDS             complement(18738..18884)
                     /gene="rpmG"
                     /locus_tag="TVW25_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1378330.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            19372..21204
                     /locus_tag="TVW25_000674"
     CDS             19372..21204
                     /locus_tag="TVW25_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1378331.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPRG
                     ENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPS
                     TITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKRKRKQ"
     gene            21516..22556
                     /locus_tag="TVW25_000675"
                     /pseudo
     CDS             21516..22556
                     /locus_tag="TVW25_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            complement(22719..23312)
                     /locus_tag="TVW25_000676"
     CDS             complement(22719..23312)
                     /locus_tag="TVW25_000676"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1378332.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(23309..24130)
                     /gene="mutM"
                     /locus_tag="TVW25_000677"
     CDS             complement(23309..24130)
                     /gene="mutM"
                     /locus_tag="TVW25_000677"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1378333.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(24545..26344)
                     /locus_tag="TVW25_000678"
     CDS             complement(24545..26344)
                     /locus_tag="TVW25_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1378334.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(26505..31145)
                     /locus_tag="TVW25_000679"
     CDS             complement(26505..31145)
                     /locus_tag="TVW25_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1378335.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(31318..32665)
                     /locus_tag="TVW25_000680"
                     /pseudo
     CDS             complement(31318..32665)
                     /locus_tag="TVW25_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(32730..34046)
                     /locus_tag="TVW25_000681"
     CDS             complement(32730..34046)
                     /locus_tag="TVW25_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1378336.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(34039..34371)
                     /locus_tag="TVW25_000682"
     CDS             complement(34039..34371)
                     /locus_tag="TVW25_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1378337.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(34381..34698)
                     /locus_tag="TVW25_000683"
     CDS             complement(34381..34698)
                     /locus_tag="TVW25_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1378338.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(34722..35621)
                     /locus_tag="TVW25_000684"
     CDS             complement(34722..35621)
                     /locus_tag="TVW25_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1378339.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            35801..37003
                     /locus_tag="TVW25_000685"
     CDS             35801..37003
                     /locus_tag="TVW25_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1378340.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(37166..37642)
                     /locus_tag="TVW25_000686"
     CDS             complement(37166..37642)
                     /locus_tag="TVW25_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1378341.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(37787..37996)
                     /locus_tag="TVW25_000687"
     CDS             complement(37787..37996)
                     /locus_tag="TVW25_000687"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378342.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
BASE COUNT        11534 a         9106 c         7097 g        10362 t
ORIGIN      
        1 ctagtctcag catagacatg taacatatga aattgagata caaaaataga cagtagcaaa
       61 cagaaaatca acattttatg cttcatggtc agcactcctt taagtattgt ttttacactt
      121 atcgtatgac taacatttca gatttgtttc agattctaga aaataatact tactattgtg
      181 cttatttaag tccaaaaatt agcattacac tcattaagta tctgagatta atctagctaa
      241 cattctaaat tgttttctcc cactaatctt ttgttcttaa ttccgactta taattaaaga
      301 caaaagctaa tttttctaac tgcctcgcat agcactcata cttgccaatc attgttgtca
      361 tcgtctcctg attgagctta gtttcttctt ccacctgctc cagtttacta gctgatatgc
      421 aagtgcaatg gtcgtttttt gtgaatcaca cctactttga atctggtaaa atcattctac
      481 taacaaactt cctgtgtaat ttctagtagc ctaggtagcc tgataaagag atttcttcaa
      541 ataaaaataa ccatgtcgaa tgccagcgct ccatttctta ccagcatttt cattattccc
      601 cagctaaagc tctatccatg aggctaagtg acctgtgctt agaattaact catatccaca
      661 ctagtctcag aaataaagac tgaagctatc atgatgtcac tactaggaat gaatgaaatc
      721 tagggtttct acttgacagt catagtgaga caaacaagcg gcaatttgct cttctaaact
      781 cccgatttgt ttctaatagc aagcataaat ctccatagac tacccccata gaaaatggtg
      841 gtgattggag aaatcaccat taagtgcttc acgacgttga ggagctttct tcttcaaact
      901 agtataaaca attaatggac tacttactct agctgtcata ggcgtttgag caatcagtag
      961 ttgaaatagc ttgcaaccga aagcacccag catactctca atgcggatcg gaagttcaat
     1021 gccacctaac tgtagaattt tataatgcaa attgtccttt attaagaacc ttattgatca
     1081 ttttaagctt tagttcggga gaggaacgaa tctttttcct tagcagcttt acaatcaatt
     1141 aatcgtgcta aatactttaa atggaattga ttgatatcaa attgtttgaa tgaataactc
     1201 tggttttgta ggccgcagat ttctaccttg tcttgatgtc ttaatgtcat gttaaaagca
     1261 ccccattcgt tagatagttt gtctaacttt tggggcgcag ttcattcatt agatttttta
     1321 tctaattttt gagaagcagt ttacttctga tgagggcttc tatattgctt tcattagttc
     1381 tatgagtgag agcaaagctc ttgtagctat ttgtcccaga tttttttatg tcatctgttt
     1441 tgcaagtcaa gctgacgtct gcttaatcag cctatctaaa accagcttgc ttggtctgct
     1501 ttttagcctt cagctgggcg tgatttgcgg gcaatatcag ccaaaatgtt atcaacaaat
     1561 gctgaaatag cttcggtatg tgttgcctta ctgccatagc ggcgcacatt aactgacttg
     1621 tcctgcatct ccttatcacc aacgattaat tggtaaggga ttttactggt ttgagaggca
     1681 cgaatcttat attgcatttt ctcattacga tcatccacat ctgcacgaat cccatgatca
     1741 cgaaggattt tagcaacctc ccaagcatag tcaatatggg cctcattgga aattgggata
     1801 actgttacct gacgtggtgc cagccatgtt gggaaagctc ccttataggt ttcaatcaaa
     1861 atagcagtaa agcgctccat ggttgaaatc accccgcggt ggatcatcac cggacggtgt
     1921 tcttctccat cagcaccaat atagctcaga ttaaaacgct caggcagtaa gaagtccagc
     1981 tgaatggttg atagggtttc ttcatttcca agggctgttt tgacctgaat atcaagcttt
     2041 ggcccgtaaa aggcagcctc tccttctgct tcaaagtaat cagcgcccat ttcatcaagc
     2101 gcagccttca gcatgctttg agcattttcc cacatctcat cgttatcgta atatttatgt
     2161 gtatcctttg gatcacgata ggacagacgg aagcggtaat ctgttaggtt aaaatcctca
     2221 taaacgtcaa taatcagctg aagagctcgc tggaattcct cctgaatctg ctctggcgtc
     2281 acaaacaggt gcccatcgtt taaggtcatc tcccgcacgc gctgaagccc tgaaagagcc
     2341 cctgattttt catagcggtg catcatacca agctctgcaa tacgaatcgg cagctcgcga
     2401 taggaatgca catggttttt ataaacctga atatggtgtg ggcaattcat tggacgaagg
     2461 acaaattctt caccatctcc catatccatt gtcgggaaca tatcctcctg ataatgctcc
     2521 cagtggcctg atgttttata aagctcaact gaagcaagcg gcggagtata aacatgctga
     2581 tagcctgatg ccagctcttt atcagtgata tagcgctcaa gcgtgcgacg aatcgtcgct
     2641 ccatttggta gccaaaatgg caagccttgt cctacctcct gagagatcat aaacaaatca
     2701 agctccttgc ctagcttacg gtgatcgcgc tccttagcct cctcaaggcg tgtcaaatag
     2761 gccttgaggt cctttttatc aaaccaggct gtcccataga cacgctgcat catgttatta
     2821 tcgctattgc cacgccagta agctccagct acatttaaca aatgaaagac ccgaatccga
     2881 cctgttgacg gcacatgagg accacgacaa aggtccacaa attcaccctg acggtaaaca
     2941 gttaagccag ccgcatcatc tgcatgctca ttaatcaact caaccttata agggtcatcc
     3001 ttaaaaagct caagagcctc ttcttttgtg atctcctcac gaatacatgg aaagttctct
     3061 ttgacaattt ttttcatttc ctcttcaatg cgaggcaggt cttcgttaga gatttgacca
     3121 tcagcattat ctgtatcata ataaaaacca tctgcaatgg cagggcctac accaagatgc
     3181 agcttgggga acaagcgctt agcagcttga gcaaacaagt gagccgcaga atgacgcagc
     3241 acctcaaaag cgtcctcatg atcagcagtt ataatttcta tactaccgtc ctcttcaatg
     3301 gcgcgcgtgg tatcaattaa ttgaccatta aacttaccag ccaaggcctt tttagctaga
     3361 gatttgctga tagagtcagc aatctcaaag gttgtgacac cagattcaaa ttcacgcacc
     3421 gcgccgtctg ggaaagtgat tgtaatcatc tgttttctcc tataaaccat ctagatactt
     3481 aaaacaagct aatcaagcag ggctatatct cccaagcctt ctgctgctac gacaaaataa
     3541 aaactgactg cctcccaaag gacgcaatca gcgtggttcc acctttattt atgcatgaca
     3601 aagaaatcct gtcctgcacc tcagcttggc tatatcgtga ccaccgtttt atgtttgcat
     3661 aaaagcaagg aaggagtatt acactagaca ccctgtgctc ttctcaccaa ccagcactcg
     3721 cttaaaggat gcgacctaat ctaacttgtc ttcctgatta ttatagcaat atttggaaat
     3781 aattcaagtg atttttccta aaaaagctga gataagccca cagacctcca agcccacaag
     3841 gcaagaatga ctaggcaagg aaccctgaaa cttctgccac aagcctttga agaacagctc
     3901 aaacaggact tgccgcctgt cgtctcagtt cacaagacaa caaactaaat cctttagaca
     3961 aatgattatc ctaaagagct atctgctctc tcacgcagaa ccaaagcctg taattgcagg
     4021 cttctttgtt tatttagcct tagtccaaaa agtctcggat cgcattgacc agcttgatag
     4081 gggctttgag caccttgaca gatgtcagtg cagttgcctt agctgctcgc ttaggcaagt
     4141 gaatcgctcc ttgaaccagc ttgattgagc cactcttttc tgttcgattg agatagagac
     4201 ttagcttttt cgtctcttta ttgtgtcgcg aaatcaaggt atctaaataa aaggtgtaca
     4261 ctgatttgcc aaaatgctga gctgaaatct catagcgctt ctcatctagc agcctctggt
     4321 tcatttgagg tgtttctaaa atggcatcaa taatcgcatc tgacaattct gactcagcat
     4381 aataaagtgt tccaaacatc ttatcggtaa tcaaatcatc taggtaggga ttgccatgag
     4441 cgatgatggg cttgccacta gcaaggctct caatataagt tagcccctgt gtctcactcg
     4501 ttgacgctga aataaagaaa tcacaggcct tataataaag cccaacctga tcatgagcaa
     4561 tcataccagt aaagaccaca tgatcctcaa cgcctaagct gacagccagc tcctttaagg
     4621 cttgaagata aggaccatca ccaacaatga caagcttgat cctgctattt tcactcaaaa
     4681 cagctggcag ctgatggata atagcctgaa tattcttctc ataagacacc cgcgacaggc
     4741 tcaatagcat ggtctcatca tcagaaatgg ccaattcctt tctcaaggca gcgacatctt
     4801 cttttttaat atcctcacga acatagttct ctagtgcaat gccagtcgga atcacacgct
     4861 taggaatggt tacctcgtac ccttccaaaa gatttagcac aatccgactt gggcaaataa
     4921 caccatcaag gtcctttaaa tacccacgaa gcaggggctt gaccatgcta ggtcgaatga
     4981 tcttaccatt agcaatatag ctcacataat cctcatactg ggtatgatag gtgtgaacaa
     5041 ccggaattct taaggccttg cccaccattt tgcccaacaa acctaagcta aactctgttt
     5101 gagtatggat aatgtctaaa tgatattcct tagcaatctt gtaggaggaa atgagcccac
     5161 gataaaccac acgacgatcc gtaaaggaca caaaaggaac acttggtaac cgaataatgg
     5221 tcggatcctc aaagcgctta acatgcttgt ctgttgttgt gaaaatatag acctcatgcc
     5281 cctctttttc cagctcctcc tttagggtgc gaatactggt agccactccg gaaacctgtg
     5341 gaaaataggt atctgtaaat agacctacac gcatcttata actccattac tttttgataa
     5401 atagccacta attgatgagc aatcctatca aggctgcgcc cctcggcgac acgatagccg
     5461 gcctctgttt tgttgctttc ccctgaaaga atgcgtctta aggctgcaac aaagcctgag
     5521 gtatcatttg ccaactcagc actgtcttga tcaatccagc cctcatagac tggtatatcg
     5581 cgtaaaacaa gatgctgccg gctggctaag gcttcgagaa ccacaatgcc ttctgtttcc
     5641 tcacgacttg ggaagaaaaa ggcgtcagcc ccagtcatag ccccctcata cacatctccc
     5701 ttgatataac cagggaagat cacattatcg gggtgcttac cgttgacaat ctggcggaca
     5761 cgagcaggaa taacccattt attggtatca ccaaaccaga taaaccgaac atctggcatc
     5821 atctcagcaa ccttaacaaa ctcatcaatc ccttttctaa gaaagaaaag ccccgctccc
     5881 atgactacct tctcaccctc tttgaggtta aaataacgcc gaaaggcagc ttctttgtca
     5941 gcattagcac catattgctc caaatcaatc ccattagata ctgcaaaaat aggagtctta
     6001 accccgtaat gctcaatcaa ggctttagaa taaggggtcg gtgtgataat ggcgtccgcc
     6061 ttattgtaaa agcggcagag ataggctttg aataaaggag acactagatt tgaaaaaata
     6121 aaggaatttc taaaatcctc ctctgtcgaa tgcccatgca tgatcacctt tttaccggcc
     6181 ttttgagcct ttgacatcaa aagccagctt ttaagcccat aggtattgag atgaaccaaa
     6241 tcatagtcgt cctttggatc agtggtgaac tcctgtccca caagcgatag cgcttttgcc
     6301 tgatgcttaa tcgctcgccc gatacctgat tttcttaaat aattttctgc ttctaaatac
     6361 aataagactt tcatactgtc tattatagcc tattttatgg tatttttcac taagagagtt
     6421 aaaaatcagc ccttagactg attttagggt aaggcttctt ctacccctat actcatctca
     6481 aaaatgcttt taagtcctgc ttttgctgtc atcaaatggc tgatcttggt aatatcagct
     6541 agaccaagat cgtgaaagct ccagctcaag gctcacgtat tagccctttc aagaaagcct
     6601 cccacctttc tcactggcca aaaagccagc aagacctggc cttttcttct gattaattca
     6661 gcctatcagc taagcttctt cttttggctg tgctttttgt aacacccagg ctgagataga
     6721 gcctgcctct accttgaaat ctgcccagcc atcctcagca acaacaacag tctcctgaca
     6781 attgtctaag aaatcacaaa aaacttgacc agcataggct tgaccaacct ccatgtgctt
     6841 ccagcctgca tcgccattag acaaaacaac tgccaaaggc tgaggacgct gatcatctcc
     6901 taagcaggtc cagccgatac aattggcatg atcaaagtaa tcaatctgct ccccatagac
     6961 cagctgctgc ctgagctctg ccatttttgt gataacctcc ttaaaacttt gctgagggta
     7021 gtctccagaa ataccataat aatcaccata aaaaagacag ggcttgccct cttgtcgtaa
     7081 aagaatcagc ccataggcta agggcttgaa ccattcctca acagttgact ctaaggcttg
     7141 ccctctttgg gtgtcatggt tttccacaaa ggtaatagca aggtctggcc gactagccac
     7201 aagactgcca tcaaaaatag tggtcaaatc aaaatcagct ccctgctggc tagcattaaa
     7261 aaaggacatg tgcagcgcaa catcaactag agcaaactga gccttcgttg cttcgaggta
     7321 atcctccata gattcctgat cagacttcca gtattctcca aaaacctcta aatcgggctt
     7381 tagctgggta cgaatatcat tgataaaggt ctgaataaaa taagaatcaa tatgcttcac
     7441 agcgtctaaa cgaaagccct caataccagt tgtctcaata aaccacttgg cccaatcctg
     7501 taaattttgg attacctcag gatgcttgaa atctaagtca ttgtacatta gataatcaaa
     7561 attaccatgc tcatcgtcaa tcagctcatc attggcccag cccttgttat caccggtgat
     7621 catgtaaata cctgtttcat tagccttggc gtcataatcc aatcccgtaa aatggtacca
     7681 gtgccattta aagtcattat aggtattttg tctgccggga aaatcaaagc ctgtccagcc
     7741 ttcaatctca tagggctctg taagggcctg ctgacggttc tctggattca ttttgatcac
     7801 agaaaagcgt tccttgtgat caccattagc cttgtggttc agcacaacat cagcaatagg
     7861 ctttattttt gcctctttta gggctgcaat cagctgcaaa taatcctctt tgctgccata
     7921 ttttgtgctg acagttccat tttggttaaa ctctcccaaa tcaaacaaat cgtaaacacc
     7981 gtaccccaca tcatcagagc tagtgccctt aaaggcaggc ggcagccaca gctgactaac
     8041 ccctagctgt tgtagctcag gaatactgct tttcagcctt tgccaatgcc ttccatcggc
     8101 aggcaaatac cattcaaagg cctgcattaa tagttgatga ctcatcttaa cctcctaaaa
     8161 aggacaaacc agaaaactcc tagtttgtcc tcaaaactgc ctaaacaggc agaactattt
     8221 tgttgtccca cgctttttaa tgccatggtt caataaaatt tctttttctt ctaattcttc
     8281 cttattcatg atcttagtga gcatacgcat gctaacagcc cccaagtcat agaccggctg
     8341 gctgatagag ctcaaatttg gacgtgtgta ctgaacgact ggagaatcat tgcttgtgat
     8401 aatctcaaag tcttctggaa cacgcttacc agcttcaaaa agaccattca aaaggcctgc
     8461 tgccagctcg tcctctgcaa cataggcagc tgtcgctccg gaattgatca cacgctgagc
     8521 cagctcaaag ccttccttat aagaatagtt ggcctcaaac accagaccct ctttaaagtc
     8581 aagcttgttc ttcttgagtc cgtccttgta gccagctaaa cgcacctttc cgttgatatc
     8641 atcaatgagc ggccctgaaa caaaggcaat gctttggtgg tctttagcta aaatatccac
     8701 cacatcagca acagccgcct tataatcaat gttaacactt ggcagctgat gatccagatc
     8761 aaccgttcct gccagaacga ttggcgtacg cgaacgagaa aactctgccc gaatcttgtc
     8821 agtcaagtga tgtcccatga aaataatgcc atcgacctgc tttgcaaaga gggtattcac
     8881 aacattgacc tctttatcat cgtcctcatc acttgaagca agaacaatat tgtacttgta
     8941 catagcagca atatcatcaa ttccctttgc cagaatagaa aaatagctat ttgcaatatt
     9001 aggaatcaca acaccgactg ttgttgtctt tttacttgca agaccacgag caacagcatt
     9061 tggacgataa tcgagacgat caataacctc taagaccttt ttgcgggtat tttcctttac
     9121 atttttgtta ccatttacaa ctcgactaac tgtcgccatt gaaactcccg cttcgcgagc
     9181 aacatcataa atcgtgattg tatcatctgt attcattctt catcttcctt tctaactgaa
     9241 aatgacgctt tcaaaaagta ttttagcatg atttgtaacc actttcaagt attaacggtt
     9301 gatttttgaa aaagttttca aaaattcata ataagcttgc ttttttaagt attttttgga
     9361 aaaatagaag gcagaaagaa ggtttatcta tgactaaatt agatcaaatt cgtttgtacc
     9421 ttaatcagga aaaggctgag cttgctatct tttctgattc tgtaacgatc aattacttaa
     9481 ctggtttttt atgtgatcct catgaaaggc agatgttcct atttgtctat catgacaagg
     9541 ctcctgtttt gtttgtacca gctttagagg ttgcaagggc tgaacaattg ctggacttcc
     9601 ctgtttttgg ctacgttgac tctgaaaatc cttgggaaaa aatcaagtct atcctaccaa
     9661 gcacagcagc aaagaccatt tacgctgagt ttgatcattt gaacattacc aagtttcaag
     9721 ggctgcagag tgtcttttca ggacgctttg acaatctaac cccttacatt caaagaatgc
     9781 ggctcatcaa gtctgctgac gaaattcaaa aaatgctgat tgctggagaa tttgccgata
     9841 aggctgtcaa tgtgggcttt gataatattt cacttgacgt caccgagaca gatatcatcg
     9901 ctcaaatcga atttgaaatg aaaaaacaag gcatcagcaa gatgagcttt gaaacgatgg
     9961 ttttaactgg taacaacgct gcaaacccac atggcattcc aggaaccaat aaaatcgaaa
    10021 acaatgccct gctgctcttt gaccttggtg ttgaaacatt aggctatact agcgacatga
    10081 cgcgtacagt tgccgttgga aagccagacc aatttaagct tgatatttat cagctttgct
    10141 tagaggctca gctaactgct cttgatatga ttaagccagg agtgactgca gctcaggtag
    10201 atgccgctgc tcgccaagtg attgaaaagg ctggctatgg cgactacttc aatcacaggc
    10261 tcggccatgg tatcggtatg gacgttcacg aatttccatc aatcatggct ggcaatgacc
    10321 tgattcttga agaaggcatg tgcttctcag ttgagcctgg tatctatatc ccaggcaagg
    10381 ttggggttcg tattgaggac tgtggtcacg taactaaaga cggctttgag ctcttcaccc
    10441 aaacaccaaa agaattacta tactttgaag ggtaatagga ggcttaaaaa gcctgaaaca
    10501 aaatgtctca gaccctaata tctaaagcaa cagcacttgg tctgttactt ttcatattac
    10561 aggctatttt ctcacaagga aaagtcaaag caccccttga tgggaaatca gaggggcaaa
    10621 agctatttgt actaagctca aaagctaatc aagagcacct gaccagctct ttatccttta
    10681 agtgataaat gcaatcataa gactgtgcat tatatttatg agctatctca accatggtgc
    10741 aggggagtga atggagtaac tcacgaatct ctctggcgct ttctttgtct agggcagctg
    10801 tgacctcatc agccagcaaa atcggtttta gtatcagcaa gcagcgtgca atttccagct
    10861 tcatgatttg cccgccagag agattttgcc catctagatg gagatcaaga tctccgttta
    10921 gctcattcca aagatgaacc tgctgtaata tctcctttag tcgctggtcc gaataatcct
    10981 gaaacagcgt gagattatct cgcaagcttc cttcaaatat gtaaggcttt tgatgtatca
    11041 aagacacaac atcataggaa ggaaaatagc gttttccatt ggcagcttca aaataaatag
    11101 ttccagaata atccttatcc tcaccacaca aaagagcaaa taaagtagat ttcccactac
    11161 cactggctcc tgttagcaag gttttgtgcc ctgctgaaat atgaccatct atcccttgaa
    11221 aaataagcct atgatcaaaa tacttatcta acctcttaaa gtagatatca agtgtaagat
    11281 catctgtagg ggttaaggct tgatgttttg tctcttcctc cagagccaat actctaacca
    11341 tcttctcctt aacagcagtt gcagactgta aactcgaagt agcttctaat aattgctgca
    11401 agggagagac aagattcgta gaagctgtta tcatagcaat gagagttgtt agtgatagac
    11461 ttgaatagct catcaccaac agaccaataa taagaggact aaccaagcca atccctttta
    11521 atggaccagt ccaaaacatt accagattgt gggtagtata atagctatat tgcttgtctt
    11581 ccatatgctg aatcatttct aacacatggt gagcaaaagc ttcgttggct tgattactct
    11641 gtatcgtgtc tgccccctta gtaaaatcgg tgatactggc taggcttttc tccctcgcct
    11701 gactaagctc taagcctcgt gattgaagta agtgattgaa cacaaactgt ggaataatca
    11761 tcaaaaagcc accaatagta aaggcaatac caatataaat atcctgcaaa agaaggtaca
    11821 agacagaggc taagatagat aggccaaaaa caggataaat gaataagggg accaaatact
    11881 cctgccaaaa cataggaata tcttgggtca aaaacgaatt taaggctgaa gtaaaatagt
    11941 tgagctgttt atgataaaaa tgatataaag ccttctttgc aataaggcaa ttaaacgctc
    12001 taaccataga acgtgctaaa atgttattaa gatacatgca catataaata aagacaaaaa
    12061 aagctacgcc tccaagacca aaaagcaata ccattccttt attgttcata tcaatttgcc
    12121 ctgctatctg aattaatact gataacaata gtccctgcaa ggaatagagc aaagccaata
    12181 aactatacaa gcaaagctgc cattttgaaa tgacttgtaa aatacttttc atatcaatca
    12241 ctcctcacct gaaacctaaa tgtatcgctc tcttggaaag tataaacgaa acatcctcat
    12301 acaccaatca tttccaccac aaactagatt cttgaatgtt aaatcaagct cttgatcaaa
    12361 atcatgttct ctgatttctt gaacaaccat tggttctctc ctttcattct tactatttct
    12421 agtatataat gggaaaaaat acgaaaggaa aaatttcgga aatccggata tgaatatcag
    12481 agagaaattt aaagcaattc gtaaacaaag aagactatcc ttaaaaacgc ttggtaaaat
    12541 agctggctca gccactagta tttctgactt cgaaaatgga aaaacgaacc tttctaatga
    12601 tgttttattg cagcttttag gctttatgat tgttgaaata aacgagctat tcgaatggga
    12661 ggattttcac gaaaaggaat tggttgaagc catcaagcaa atcgaactgg caataaaatc
    12721 taaacatatt cctgctctat ctcagctaca gcaggacttt caaagcttat ctaagacaaa
    12781 ggaacagtac atttaccaca tcatctcact gatcctaacc atcaccattg cagaatatca
    12841 aaacaaagag atcgatccac acatcatgtc tgagctaaca gactacttct ttttcttgga
    12901 gtattggact aaccttgatg tcggcctact aggaaacatc gtccactaca tgacaacaga
    12961 tgccctaatc ttattgacaa atgacatctt agagcatacg cctcaagtac tccgaaataa
    13021 cctagatcgt attaggatcg atactgtatt aaactgtctt actgtcttga ttaatcgtaa
    13081 agaggagaag gcaagcagaa cacttcttaa attattattt aacaaacatt atcctaatta
    13141 ctttgccttt gaaaagctct atttacatga attacaagca gtctatgatt ttaactggaa
    13201 agataaagaa caggcgcttg cagctcatca cgtcatactg gctaccattt cattactatt
    13261 tacagctgat gaagccaaag aatgggacag cttctttcaa gaaagtacta gctctttgta
    13321 atactccagc tcatacacta aagaaaagca aggataatca cataaaaact aatcacatca
    13381 ctttgccctg ctagctgaat tagcttgggt catctcttat gcccagcaaa acatcatcta
    13441 gtctcagctt tcttccaaag cttcttgtct ctctgggctt gcaagctttt gatagcttaa
    13501 gaggcacaag cattaacaaa ggctaacaaa tgcctgtaaa aatatgctat gataggggta
    13561 acaaaaacct aggaggtgct tatgtcacac aaatccattc atcaacagct tagaaatgct
    13621 ttttcctttc ggacagcggt acgcgtctac aatgaccaaa aaatagccaa agaagactta
    13681 gacctgattt tagatgctgc ctggctcagt ccttcctcta tcggccttga ggcctggcgg
    13741 tttgtcgttt tagaaaacga agctgtcaag catgagctaa aggaggtctc ttggggagca
    13801 gtttatcagt ttgagacagc tagtcatatg atccttttaa tcagcgaaaa aaacgccaga
    13861 tatgatggcg cttctatcaa gcaaagctta ttgcgcagag gcattactga cgagcaagcc
    13921 ttggccagtc gtctggcatg ctacgaagcc ttccaaaagc atgatatgaa aatagcagat
    13981 gatcctcggg ctctctttga ctggactgcc aagcaaacct atatcgcgct tgctaatatg
    14041 atgaccactg ctgcttttat ggggattgac tcttgtccga ttgagggctt taactatgac
    14101 aaggtaaatg ctatcttagc aaaacatggg attatcaacc ctgataccga gggtatctct
    14161 agcatgctgt ctttaggcta tcgcctgcgc gatcccaaac actcacaaac cagaaagccc
    14221 agagaagagg ttatttcctt ctttaactaa gccccttttg ccattgctcc caaagaaagt
    14281 gcaaagacag tcctttgcct tttctttttc ataactgtcg aattatggta caatgtgtca
    14341 aaagacctat ggaaagtgat gcctatgaca ttattatctg taattatccc ctgcttcaac
    14401 gaagaagaca cgattattcc ttatcttgaa gaaatgaagc aaatcgaagc ggccatgacc
    14461 agccaattag cctttgaata tctttttatt gatgatggct ctacagatca aaccctgagc
    14521 gtgctaagag agcttgcggg gcgcttctct aatgtgcatt acctctcctt ttcacgacat
    14581 tttggcaagg aagctggact attagccggc ctagaagagg caaaaggaag ctatattacg
    14641 gtgatggacg ttgacctcca ggacccaccc gagcttctcc cgctgatgta tagcaaatta
    14701 caggagggct ttgatgtggt tgccacaaga agacagagcc gacaaggaga gcctgctatc
    14761 cgttcctttt ttgctagact cttctacaga ttagtcaagc atgtctccaa caccgaaatc
    14821 gtcgatgggg tacgtgatta tcgtttaatg acaagacagg tggtggatag tattttagag
    14881 ttgggagagg tcaatcgctt ttccaagggg attttttctt gggttggcta caatactgcc
    14941 tatatcagct ttgacaatcg taagcggcag tacggcaaaa ccagctggaa ctttcttgag
    15001 cttttgaact actcgataga cggctttatc aatttttctg agatgccctt aaccattgct
    15061 acctggactg ggacacttag ctttttgcta tctctgctag ccatttgctt tattgttata
    15121 cgcaagctgc tttttggtga tccggtttca ggctgggcaa gcactgtatc cattatgcta
    15181 tttatcggtg gaattcagct gttttgcatg ggaatcattg gaaaatacat ttccaagatc
    15241 ttccttgaaa ccaagaaaag acccgtctac atcatcaaag aaaagaaata acagagcaat
    15301 catcaaggcc cctatcagcc gccaatgagg ccgataagga ctggttgccc tcatcatgac
    15361 aagcacgaca aaaagacttg atggtcccaa tcaaaaccat caagtctttt ttagtatgtg
    15421 accttgcgtc tgcctcgcac ctaaaaagac gagataatgt cataaccacc gtctatctac
    15481 tgaccccaaa aagttggaca atttagtttt aagcaaggga tttagttctg tattgcacag
    15541 gactaagcaa ggccatcagc ttgtaaacag acgcttagcg gcggttcaca ctcttcatca
    15601 cacgccgaat gtcacgatcc tgctcgcgtc gcttgatcga ttcacgcttg tcataatcat
    15661 gctttccttt ggcaaggccg attaacacct tggcaaagcc atccttaaga taaaccttta
    15721 gaggaataag ggtcattcct gtgcccttta gctcatctgc taggtgctga atctcacgct
    15781 ttttgagcaa taatttgcgc gtgcgctccg gatcagcatt ccagatattt ccctgctcaa
    15841 agggagcaat atgaacattg accaaccagg cctcaccatt cttgatttgg gcaaagccgt
    15901 ccttgagctg gatacgcgcg gcacgaacac tcttaatctc cgtaccggtc aacacaattc
    15961 cagcctcaac tgtctcaacg atatgatagt catgacgagc ctttttgtgt tgcgctaata
    16021 cattaccttc accttttgcc atgcttaact ccttttacga cctttctttt tagcagcttt
    16081 ttggtaaaat ggtttctttg ctttttttct tgtcttctgc tttgattttg gctttgaggg
    16141 cttggactcc ttactcctgc tagcccttga agcagccttt tgcctgtgct tatgcttagc
    16201 tttagctgac cttgtggtct tttcaaccac atcatagtca ctagccaagt aatcaaaatc
    16261 aatgtcacct gtttccttgt cagccctcac caatctaacc cgaatcggct gacctgctct
    16321 aaataccttt cctgagcgtt caccctttaa ggagagtgtc cgttcattat agtgataata
    16381 ttcaggcaaa ttggtaatat gcaccagacc ttcaattgta tttggcaatt cgacaaacat
    16441 gccaaactta accacactag caatcacgcc atcaaacaca tcaccaatat aatctgccat
    16501 gtattctgct tttttcatcg cctcaaccac acgctccgcg tcaattgcac gacgctctag
    16561 ctgagatgac gatactgcca attctggaat aacctgtgca aaatgatcca ccttctcctg
    16621 cgtgatctga ttgtattctc gaatcatgcg gtgcaccagt aaatcagggt aacgacgaat
    16681 cgggctggta aaatgcgtgt agtagtctgc tgctaagcca tagtgaccat gattatgctc
    16741 agaataccta gcctgctgca tagagcgcag cagcatcata ttcaaaacct ctgctccagg
    16801 acttccttct acctttgcca taaaggcctg caaggcttct tgagaaatct tattagcagt
    16861 tccctgaatc tgaatcccaa aggcactagc gtaatcaata aaggtctgca atttctctgc
    16921 ctttggctcc tcatgaaccc ggtaaataaa tggcaagcca gcccttgaaa aatgctcagc
    16981 aacacattca tttgccgcta gcataaagga ctcaatcatg cgctctgcaa cacctcgctg
    17041 gcgcaagacc acatcaaccg gcatgccctt atcattgaca ataatcctag cctcctgcgt
    17101 gtcaaagttc aaggccccgc gcttcacacg catcgcctct aagatctgat gcagctcaac
    17161 catagtactc acatcatcag caattctatc aaattcccta agcgcctcac tgtcacctgc
    17221 aatcatctga ttgaccgcgc tgtaggtcat tctaaaggtt gtgttaatca ctgactgaca
    17281 cagctgataa tcaaccacat gtccctgatg atcaatctcc atgatcgctg actgggtcaa
    17341 ccggtcaacc tttggattga gagagcagat accatttgac aaccgctccg gcagcattgg
    17401 caccacacga tctgtcacgt aaacagaggt cccgcgcgca gctgcctcac gatccaaggc
    17461 tgacccttcc gtcacatagt aggacacatc tgcgatatga accccaagct caacgtttcc
    17521 attggccaat ctcttgatat ggatggcgtc atctaggtct ttagcatcag caccatcaat
    17581 agtgatggtc gtttctttgc gcaaatcaac acgccccata agatcctgat cactcggagc
    17641 atctggaatg gcattggcct cagctagaac gtcatctgga aacgccgata caatatccat
    17701 agattccaaa acctccagca catcaatgcc gacatcatgc tgatgcccaa taatatcaca
    17761 cacagtccct acaaaataat cctgcccagc cttagggtat tgcacaatat cagccttaat
    17821 gatttcagta ccatctaagg caattggaga ttttgcgata taaatcctct gttgaatcct
    17881 ttgatttttc gacttgatgt agccagcata cttagggtga tcatcatcta aaataaccct
    17941 accaacaacc gtctttaaag agcgctccac gatagctacc acgcgagcct ctgctgctgt
    18001 agccttaagc cgattagctg gttttttaat aacagcctca accctatcgc catcactagc
    18061 ataccccaca tcatcacgac caataaaaat gtcgtcctca ttgtcatcaa ccgacaaaaa
    18121 gccaaagcca gccttattgg cacgaaaaat accttgaacc cttatctctg gctttttttg
    18181 ctgtggtgct ctaagaaaca cctcaccctc atctgaaaaa gacaaaagtc ccttgccttc
    18241 cattttggaa atggctttaa tcaggcgagg aaagctcctc gcatcagtca tctctagtgc
    18301 agccgccaaa tcatgaatat ttgattggcc atgctccttt aaataattcg taatgttctc
    18361 tatcatcata cctatcttct atttctaaca ccatacttga tggttgtgct cattgataaa
    18421 aaaatgagct agactaactc tgtcaagctc actccttatt tacttgataa aatggcaagc
    18481 actaacgcaa ttcctaacca aaaaaacact agaactgctg taaaacgttg cataaaagct
    18541 tcaaatccgc gagcttttgt acgctcaaac aaggcttctg agccactgct atcaaaaaca
    18601 ttgctactag gatttttttg tggctgcata aagatagcaa tcacaagcaa cactgataat
    18661 actagcaata tcgtaagtag taagtcgtac atgttaattc ctccactgta gtctcaatca
    18721 ttctaacaca aaaccaacta agattcaaca tgcagcgtta cttttctctc cttaggacag
    18781 tatttaggaa ccttaatctt ctcagggtga cttgttttat ttttactagt caaataattt
    18841 ttgctgccgc aatggctgca ctccaaatga atctttactc tcacatcatt tccctaatct
    18901 tactatattt tatcagcgtc ataaggcttc aaatcacccg cagcttcttt attaaagata
    18961 tctctagtta ttatagcata ttatccagta agaaaacaaa ctcaggactt ttagcaaaaa
    19021 aggcttaagc gccaaccaat aaacattcca aggctatcgg ggaatatttt ctaatggtta
    19081 ttataaatca tgaacaatta cctaacaaag caactccaaa acaaagataa aagacgaaca
    19141 ttcaccttgc tgctcagcta tcaagataaa caatcctgat agcatcaatt ttctttaggt
    19201 cctcagcaat cggttgtaat atcagacaat tcaggtgttg attaaaaaaa acgaaactac
    19261 ggagaccaat tgtcagaaag ctattcacag cccgcaggcg tcgtgctaaa gtattgtctg
    19321 gaaaaagaaa ggtttaggaa tgattatacc taaactcaaa ggagagaaac aatgagaaaa
    19381 acaatgaaga agatgctagc agcctcgacg ctctgcatca tcatgtcagg cagcttcatc
    19441 agcggctcag ctagagtgtt ggcggagaag tattatggtt ttaatgatgg cacaggagag
    19501 cattcaccat tccctgtata cgttactcca attactaaac ctaataggaa tactgccaaa
    19561 gttgtctact gtttcaataa agatatgaag tggccagaaa cttgggataa agcagcacca
    19621 aaaaaaccag ataatttacc tctatactac gatatggaag gtactgatca attattcagt
    19681 acatatgcaa gtggacaact tactcctaat gtcagtaaag tcttagctaa tataatggct
    19741 aaaggttatc caaacaacaa tgagtttgct caccatttta aactcactcc caattccgct
    19801 gtaaaagtta ctcaaatcgc agtttggact gttacggata acctaaaaaa ctattctcaa
    19861 tacagtctaa ccagagaaga ggaagctgca ttaaattacc taactgacaa aaatggggac
    19921 gactttagcg atagtatcaa gttaaaatta tacattccac aaaatcctcg aactataaaa
    19981 tatcaaaatc ttctaggtta tgacctaata gttaaaactc cagaaaaaaa agataattgt
    20041 aaatgcacca aaatttatat agaagataat ggaaaagatg gctattatct gtatatttat
    20101 tatgacaaca atgaaaataa tagatatgac tcggacaaag atagcctatt gcaaaagaaa
    20161 tacataaaaa atgggaaaga tgggaaacca ggaagaccag gggttccagg acttcctggc
    20221 cctgctggac ctcaagggcc tagaggagac aaaggagaaa ccggggaacg tggacctaaa
    20281 ggtgaaaaag gtctagacgg taagcctggt gaaaagggtc ctaaaggcga tacaggaaaa
    20341 gatggtaagg acggacaacc cggacctcag ggacctaagg gtgaccctgg acgtgatgga
    20401 aaagatggcg aacctggaaa acctggcgag cgcggtgaga aaggacctca aggcgaacgt
    20461 ggacctcaag gacttcctgg gcccaaaggt gagcctggaa ttccagggcc taaggatgaa
    20521 gatggaaaag atggtgctcc tggacatgac ggacaaccgg ggcctaaagg tgaaaaaggg
    20581 gaccctgggc aacaaggcat tccaggacct aaaggggaac ctggacgtga tggtaaagat
    20641 ggagaaaaag gcgagcgtgg agagcaagga cctcaaggcg aacgtggaga gcaaggacct
    20701 caaggcgaac gtggagagca aggacctcaa ggcgaacgcg gggagcaagg acctcaaggc
    20761 gaacgtgggg agcaaggacc tcaaggcgaa cgcggagagc aaggacctca aggcgaacgc
    20821 ggagagcaag gacctcaagg cgaacgtgga gagcaaggac ctcaaggcga acgtggggag
    20881 caaggacctc gtggagaaaa tcctactcct accccagatc caatgccaca accagaacca
    20941 caaccagaac cacaaccaat gcctgatcca gcacctaaac cagaatccaa gccagaacct
    21001 aagccgatac ctcaaccaga ggttaagcct cagccagaga caaaacctca acaaccaaac
    21061 aagccatcaa ccattactag ccaatctagc ggcaaatcac tgccaaaaac aaatgacact
    21121 ggcagcttga tcacagcatt tggtacaggc ttactcactc ttcttggact aggcttccta
    21181 gcaaaacgca aaagaaagca ataattaaaa cactacccat agccttttaa tcattggcta
    21241 tcaactagat aacaaaaagc ttatcgtttt actcctaacg ataggctttt tcgcattccc
    21301 tattgcttgg tctcaatact atttttccag ctttaggctg gttttgctaa tccaaaataa
    21361 tatcagacaa tttccgtttt aattaaaaaa aaaaaaacga aactacggac gccaattgtc
    21421 agaaaatggt tcacagctta gagtcaccat gttaagctat tctacgaaga agaaaggttt
    21481 aggaatgact atttctaaac tcaaaggaga gaaacatgag aaaaacaatg aagaagatgc
    21541 tggcagcctc gacagtctgc atcatcatgt caggtagctt tatcggcgga tcagccagaa
    21601 tcctagccga gcagtattat gggtggaatg atggaacaag agtaaaatca ccttttttcc
    21661 tttatgttac gccaacaaat gaaacgacta ggaaaaccgg aaaaaatggt acaatagtct
    21721 attgtttcaa cagagataag gaatggccag caaattggga agaaggaaga tccttagaac
    21781 tagtgaatgc tgaaacagct tataaattac ccatctataa taaattacta ggtacaactg
    21841 attcctttac taaaaatgct agtaaaccaa gagtatctgg agatattggt aaagcgctaa
    21901 tagctgtact gaaaaatggt tatcctaata aaaatttatc cggattagat gacactaaaa
    21961 gtcgaatact aactcaacta gctatctggt atttcagtga tagttataat aaagattatt
    22021 ttaaacaaaa ttatgaatta actgatcaag aaaataactc tcttatggag ctgattaaag
    22081 tcggtgagga agcagctcaa aaacaagaaa aaccagaata tcatttagat atatatataa
    22141 ctacagaaaa aaattattaa cataaacctt atcaaaacct gcttggttct actctaattc
    22201 ctaaacttga ccctaagcct gaaccagaac cagatcctaa gcctaagcca gatcctgaac
    22261 caatgcctaa accagagcct aagcctgaac cagagcctaa acctgaacct aagcctgaac
    22321 caatgcctga tccggcacct aaaccagagc ctaagcctga accaatgcct aaaccagagc
    22381 ctaagccaga gacaaaacct caaaaaccaa ccaagccgtc aaacgctact agccaatcta
    22441 gtggcaaagc actaccaaaa acaaatgaca ctggcagctt gatgactgca cttggtacag
    22501 gcttactctc tcttcttgga ctaggcttcc tggcaaaacg caaaagaaag caataagctg
    22561 aataagctaa tgcaagacag cactagtata taatgcgtgc atggtccatc taatgcagca
    22621 caaaagcctt atcgcaccac gaatgggtac gataaggctt tttgcatacg ctatagaagc
    22681 tccaaaacca ctagactagg gcaacagcat ggcaaggctt acgcctctaa atcatgcaga
    22741 gccttactaa tctgtgtctc taaagcctga aaatcaccag tattatcaat cactaaatca
    22801 gcataagctc ttttctgaga catcggcagc tggctagcaa tccgctgcct agcagctagc
    22861 tctgtcaatt gattacgctt catcaggcgc ttgagctgag tctcctcatc aacatagagc
    22921 agccaaatag cgtcaaacca atcctgatag cccagctcaa ctaaaagcgg taaatccata
    22981 aagaaaatag cctctgtttg agatagctcc tctttttgct tggctaaggc ttccctaatg
    23041 atagcattct gctgctggga agatttcgcc atattttccg aatgagcaaa cagcagctcc
    23101 gctagcttag gtctgtctaa ttgccccgat ggcaataaaa tatcctgtcc aaaggtctct
    23161 agtaggacct gataaagctt gccgcccttt ttttgcagct catgcaccac ctgatccgca
    23221 tcaatcacct ggtagcctgc ttgtctgata agtgcgacag ccgttgattt tccggaggca
    23281 atacctcctg taatgccaat tacctttgtc attgcttctg acacctagga cagacatgtg
    23341 tccctcttcc tccaaccttg agctttacaa tggaggtccc gcagcgctga cagggcttgc
    23401 ctgtttggcc atagaccatc aaataatgct gcatactacc attcattcct aaggtattct
    23461 gataggttct aaccgtcgag ccaccctttt caatacctaa ttgtaaaata cgaatcgttt
    23521 catcatgaat ccgtttgatt tctgcctttt tcaggctagc agatcgacgc tcagggtgta
    23581 ctctagctgc ccatagcacc tcgtccacat agatatttcc aagaccagcc actaaagtct
    23641 gatccaaaag atgaggctta atggtctttt tagaggctag cagagcagcc tcaaaggtct
    23701 tcaattgaaa ggtctgcttc gtcggctcag gaccaagctg acgcttctgg aaaaaagcag
    23761 ccagctcagc ctttggtagc aaatcaaagg ttccaaactt tctcacatct tggtaaacca
    23821 gcgtggagcc atcagtcatt gtcaaaaaga catgaaaatg cttatgctca ggtaccgtat
    23881 caggaaacaa gaggtatttc ccctccatac gcaaatgcga gatcataacc agctggccaa
    23941 agtcaaagag caggtacttc ccgcgacgat ctaccccttg cacctgctgc ccagggatcg
    24001 tcatcacaaa atgctcaagg tctgttttga ccatcttggg caccctaact gtcactgctg
    24061 caatctgctt gccaacgact aagcgctcaa gcccgcgtcg cactgtctca acctcaggga
    24121 gttcaggcat aattaaagat accaaacgcg ctaacaaaga aaccacataa ccaaaaccag
    24181 cagaaccagc cagttttagc actctttact cagtctcaat gttacaaaca cgcttccttt
    24241 ctataagcta ctattagaaa gccccaccca aaacctcaat aagcttgagc acaaaggact
    24301 atcctttgat aagaactgtt atcattctta ttttacgcat aatccataaa gaaagcaact
    24361 ctcacgaaca gcctttgcag tcactgccgc tatagcatca gaaaagcaca tctcgcccgc
    24421 caatccagca agcaaagaca aagcccctga gctagcctat tgtttgccag cccaagggca
    24481 cgttgtggcc tttagtgtct gtaaatagaa aaccaagcaa tgctgcaagc ctcaactgac
    24541 aatgctaggt ctgatcagtc ctgtcatcag cttgcggata atctatacta attggcctat
    24601 caacaagacg gatactatcc tggtaaacac cttctgtttc aaaaataaca atgtcattta
    24661 atcccttgtt gaaatagccc tttggaatat aaagggttaa taagggaccc acttcccaaa
    24721 aacgaccaat agggtgattg ttgataaaga cacaaccctt cccaaagcca gtcatatcaa
    24781 tatagcttgc ctcaggctca tgacattcaa attgataatg ataaaagccg ggctgcccct
    24841 cgtaaaaatc gccatcaaaa caaagctgag acaaatcatc aagcggcaga caatacatct
    24901 cccaattggt cacaaagtgc aagtcagcca tcataccacg tcctagaccc ttactttgac
    24961 taggtgctgt cagcttgtgc ccataattga cccggcccat attttcaatt aaaacatcga
    25021 cctgactcaa ggcatgctgc tggttaatga tgatatcatc accaatcgtc tcctgatact
    25081 gtgttgcaac cttttgacca tctaaaaaga cctgtgctct atctctacta tcaatcaagc
    25141 gtaaacgctc gtcctcacgc ttatccttca aaagatgtgt ccgatacagg atatagcccg
    25201 ttgattgccc taaagcctct atgttactag gatagcaagc agtctgacag ctgctgatgt
    25261 gctccagcgt gctaaacaga ctaaccttgt ccttcagacc aatcagaggc agtgacatca
    25321 agggcttaat caagggagga gtaacctcta tctctgaaag ctccgcggtc agacgctttt
    25381 gaatcgcgta aaacttagct gtcggattgc cagcctcatc taggatagcg tcataatcat
    25441 aggaggtcac ctgcggaagg tccaattgct ttctggcaga gcagccattc ataaacccaa
    25501 agtttgttcc cccatgaaac atatacaggt taatactgcc ctgcgccaaa acctccatca
    25561 ctgcgtcagc tcgctcttca gggtcgcgtt tgatgatggg ctcatgccaa cgattgaacc
    25621 agccgtccca aaattccata cacattaaag gccaatgctt gccatgctca gaaaagaagg
    25681 cctgcatgtc agcaaaattc tcctgtgccc ttgagccaaa gttgccagtc acaaagacat
    25741 catcttcaat cagactacca gctctaagag tggctcgcca aggaccatct gctgtaaaca
    25801 agggcgcact gaggtgctcc tccataaagc ccttaacagc tgttaaatag gccttatcct
    25861 ctccatagga gccatattca ttttcaagct gaaacatcaa aatattgccg ccctgctgcc
    25921 attcatgcct tgctagtctc ggcagcagct cctcataata gcgcctcaca taggctaaat
    25981 agacaggatc agacgacctg atatgacaat tctttgtcag cagccaagca ggtaggccac
    26041 caaattccca ttctgcacaa atataaggac taggtctgac aatagcatag agccccaatt
    26101 gctgcgccag cgtcaaaaag gcttccacat ctaattggcc agagaaatca tagctttcct
    26161 ccctagcctc atgtaaattc caagggacat aggtctcaac cgtattaaat cccagtgcct
    26221 ttaaattata aagcgaatga taccaatcat ctgggtgaat tctaaaataa tggatagccc
    26281 ctgacaggat ttgcagcgat ctaccatcta aataaaactg atctgaaatc tgaaaacgtt
    26341 ccaagcttaa ttcctcactt attattgcta ttagcctact aggcctcatt gctgagcggc
    26401 ttggaatggc ccattctagc aacagcgaac aggccattca gcagacaggc taacttatct
    26461 tatggtaaca attgtaaaca ctatctacag tctgactcct catgctatgc tgtcacagca
    26521 gcaggataag agacagtgta tgccttgtca tctgtcaatc taatcccata tttggtttca
    26581 acaatagtat ggtcaaactg cggtaaaaca gttatcggtc cttcaggcat actctccaga
    26641 gacaattcaa atatcgctgt gtctgtgcca tctcctgaaa catagctggc aagcttatct
    26701 acgccattta cagtaactgc taactgacga tcaccaagaa taaacatcgg ttgattaaag
    26761 gtcatctgaa tggttatgct tactttgcca ttttgctttg gagctgctga cgttattgtt
    26821 acttcttcaa tttcagcctt atcctcacga aactggtctg agatcatctg cttgatatta
    26881 aaggttgaat aggtgatctg accactatat tcgtataaca aaccaaccct ctcgtcgtct
    26941 agttgaacca agctagagta agcaaaacgc tttggctcaa aaatggttga agcgacccaa
    27001 tgaatgctat cgtcctctaa gacctcaccg acacgcagaa tccctttcat gcgctgattt
    27061 ctaatcgtca gttgctcacc tgagggctct cctaaaggat tggataaaac aacatattct
    27121 ttgccatcaa ccatcatatg aatagctgac aaattgacat aaggctctgg gaggtctgtg
    27181 attgtaggat tatcgtccca agtcatacca tagtctgtgc ttctggcaat aacgattgtc
    27241 tttccggtat tgcgcataaa ctgtaataag tgaccattgt ttagctgaat gatttgattt
    27301 tctgtcaatt ctgtgactga tgtatcaaaa tccttagagg ttgtttgttg gttatgacca
    27361 taaattctgc catcatttgg tgattcacct cgttgccatg tttgaccgcc atcatcacta
    27421 aaaatattag cactgctttg acgacctaga ctagctgatg tcgcattttg ttgattggta
    27481 tagtaaatcg ggaaaactaa ccgtttcacc tgctcaccct ctgcattgac tgcgtctatt
    27541 tcaatgccag ctgcggcacc cgtacctaaa aatcccatcc agtcttcttt tatttgtggg
    27601 gtaatatcaa gaggtgtgga ccaggtttgc ccttcgtctt cactggttag cagccataaa
    27661 aagctggtca tgtaagtaaa tagaggagct gtttgtgagc cttctctagt gatgccttgc
    27721 ttagtgcgac cacttctcag ataaatattc cctagtagaa tatcctctcc tgcctctgtt
    27781 tgatagaggt tgccgcgtgt gctaaaggct gtctcaaaat tgccctcatc aacatacata
    27841 tctgtctgat ggccactctg gtcatagacg ataccacctt cacgcacagt gtatttatta
    27901 ttgtcaaaat cataaagatt taaataatac tgaccgttaa tcaattcata tcctgagcct
    27961 gctttagaag caacagcacc ctgtgactca ggaaagacat ctaccagcaa ataaagcttg
    28021 ccagaagcgt ctgttagcaa ggtggagtct attgaaaaag cagattgagt catgttggta
    28081 ttccaatcag ccaagctata ttgtgttgta aaataaggct gagttggcat atctaagacc
    28141 gtaatgttat tactccaggt tttgccatca tcatggctta tcctgacaac agttgcaaca
    28201 tctccccagt cattgtagtg cttctttctt gcatctgctg cggctatcaa ggttcctgat
    28261 ggcgttttga caacagaggg aatccgatat tcaaagaccc cttcatcata tttgtcccaa
    28321 acattcgtct tttcaccagt aactggtcga agggttggct gatgagcctt ggcaatatct
    28381 gtcagatcat acacatctgt atcaatcagc acctgatcaa ccagtccctt taacccccag
    28441 tgaaggaccg actcaccatc ataggtgcgt ttcaagcctc caattgttag cgtatcagca
    28501 gaagccttcc aaggtaattg cttcataaac ccagcaaagt cagcttcccc atataagtca
    28561 ccattcaagt aaatctttag cctagaccct gtaaagacat agctgatcgt ctgccagtcc
    28621 gagttcgtta ataaattaaa gcctgagcca acttttacaa tcggaacctc agctccttta
    28681 aattcaagac ctattttatt gtttttaggc tcgataaaga aagaggcgta ttcattagct
    28741 gatgcttgat ttgagatcga taacaaggcc aagggcgatg agcttctcac tgttgtatca
    28801 gcagtatcta gacggtatct gattgttaca gttccttggg ttaggttcat cacatcgtct
    28861 agcttaccaa gagcctcgtc atctgttacg gctgcttttt ctgctgttgc gtccaaaata
    28921 gcattgccta aatcaactaa aatggatgct tgatctgaga ttggctgatc tgagatatag
    28981 cttgcttcta tgcttgtata aacagctcgt ccgccttctg tggtgtattt gatctgataa
    29041 tgctctgcac ttcccaagat ctcctctggc gtaacccatt gccaattggc tggcagggct
    29101 actgtagata agggttctcc cttcttacca atcagacctt ctttaggtaa tacagttaaa
    29161 atagctactt ctcttgcaat cttagcagtt ggtgttactg ttgagcctaa atcagcattg
    29221 taaggaacag cactatagta aatgttataa ataccaggag ctagctcaga caaggctgac
    29281 aaatcatctc gaccagcagc ctgtaaagca gcattggtat ttccaccctt gttagtaaac
    29341 aagtattcat tttcaactga aaaatcaacc acatagcctt cctgatcagt ggttacagct
    29401 tgagctaaat caggactggt tccctctagc atggtcaaat ccttgacccc cttgagaact
    29461 ggctgtgagg cataataagc ttctgaggct gctttttgct cagcatcttg gtaataacgc
    29521 acataatcaa tcacaaaggc cgtctcatct gaagctagat agtagcctgc atttttactc
    29581 caattgcctc cagtagcaag gttaaactga aggtattgag gcttattaaa ggcagctgcg
    29641 gcagcctcta agcgatcatc accggttaaa tacatggtat tataaacaat cccatcaaca
    29701 taccattcaa tcttatccgg ataccaatta ataccaaaga tatggtagtc atcataaaag
    29761 tcatcactta atgtcagatt gccacccaat gctgttgggc tatagcttcc atctttgtct
    29821 gcatcaccct tgatatagta aaaatgaggg gtcccgtaaa ctgttttgtt gctttgatca
    29881 ccttcggcaa gctcaccctc atgctctccg ttaggagcac cgattagctc cataatgtca
    29941 agctcacctg tgcttggcca gccatagcct tgagttgacg caatatcacc atctaaggta
    30001 aaatcagccc ccaatgtcca aaaggctgga aaggctccct tacccttggg aagcttggcc
    30061 ctagcttcga tacgaccata taaaaattct tgcttgccaa ccgttcgtac gcttcctgaa
    30121 tcataaatga cctgacgtgc gcttgttcct cctctaggat tggcataacg gtcctcccca
    30181 taacgctctg tgacgtttaa aacaagattg ccattatcaa gatagacatt ctctgtgctg
    30241 tctgtgtagt gctgctgctc attcccgcga atacttccca attcatatcc ccagttctct
    30301 tggtttaacc gatctcctga aaactcatcc tgccaaatca attcataatc attttcctct
    30361 acgacactca cgttatcaat actagcagag gcagccaagg cttccggaga agaggcttcc
    30421 aaccatttga ctaagccaac aaaggtttct gaagtcgttg ctgtaaagga gagcttgata
    30481 tgtgaccaag taccgtctgt atctgtgagg ctgacctctt tgataacagg gccctgaaga
    30541 ttgtgattgg actctttagc ggtaaggtat aagccattat gaggtgtgtc agcttcaacc
    30601 ttcacatcag cctctagcgt ataggttttc ccaaccgttg tagacacctt ttgaaggata
    30661 tgctcatcta aagtgccgct tgttacctca gcatagctat taccattctc tgttgtgagg
    30721 actgaatgac ctccctctct atattgccac tgattcttat tggacacata atcattgtca
    30781 aaaccaccat tagccacctt attgagctca atcggagcgt tagacttctc ttcgtctgct
    30841 gtctgatcag cagcattgct ggtcacagca ttagctacta ctgcctcatc tactgtcgtc
    30901 tcctctgaga ctactaaggc ctcgctatct gtatctgtag cttgaggctc ctgctcatgg
    30961 cttatctctg ttactgctgc tttcgtaggc tgctgcaggc ttacctctga aacgtcatca
    31021 gcataaacag ccactggcag accagcagca agaccaatac ccacacacac tgaagcaaca
    31081 ccgacactaa gctttttgat ggcatatttt ctaatttgct cttttccgat aggattaaat
    31141 aacatgttta tttcctcact tatatataca tcatttttaa acacaatagc ttttcaaagg
    31201 cccatttagc ctaatccagt gctggtcagg ctaacgacct tgttataaaa acgctttcaa
    31261 ttcagcgctt aaaagaagat ataccagatg aaaccgatat atcctctcac aaagtgacta
    31321 acctgccttt tcaagctcat tatcagccat cttaacaaat ggaaggtaaa tcaggtttgc
    31381 caaggccaaa ttgacaagcg atagcacaat agcacgccaa tcaaaaccag ttgaaaagaa
    31441 gccatacaag acaggcggca ttacccaggt cacattttgc gtaacgggtg caaccaagcc
    31501 cagactagtt gcgatataag caacacttga cataacagca ggacaaacaa taaacggaat
    31561 aaacaacaaa ggatttaaaa cagttggtaa accatacatc actggctctc ctatattaaa
    31621 caatacagga gcaacaccta gcttagccac ctcacgatag tgttcatttt tagacttcca
    31681 gaaaatagca atcaagagcc ctaaggttgc ataccataca aagaacactc gtccaaagat
    31741 aaggaatcgc ctcatgcttt tgataagcct ccaaattagc caagagggca acaccaaata
    31801 ctccctccat atttggcgcc ataacattgc cgccatgaat cccaaagaac cagaaaaatt
    31861 gggtcaaaac agctaccaaa acaacagcaa taaagctttg tgataagccc aaaagtggga
    31921 tttgcaagac cttatagatc caatcaatca tcaaagaacc cgttagcttt tcaaagacaa
    31981 atgttaaaat agctacgcta tacaaggcgc aaaagcctgg tatgatagat aagaagggct
    32041 tggctacagc aggtggcaca ctatctggta atttaattgt ccaatttttt aacattaatt
    32101 tacaaaaaat aatagaggct aaaaagccaa tcataattgc tgtaaaataa ccattggagt
    32161 taatttgcgc accaggcaat aggcctgaga tggtcacatt aagtgagctg ccgctgacag
    32221 taacaccact gtccttaaaa gtcgtcacaa gatcaacacc cttgagacct gacgcgtcaa
    32281 tgctagaggt aacagaatcc ccaatcgcaa tcacaaaggc agctaaagaa accaaacctg
    32341 atgagagcgt atctgtctta taaagtttag cgacattaac ccctaagcaa tacacaaata
    32401 gcaaggacac aatcgaaatg cttcccttaa agacaaggtt gttgatggtt acccaccatt
    32461 ggaaggcctc tgtaatgcct tgcaagccaa attggtctgg aatatccact aaaaaggcat
    32521 tgatcaacag ggcaatagag cctgtcatca caaccggcat cgttgcaata aaagaatctc
    32581 gcaaggccac taaaaatcgt tgattaccaa tcttcgtagc aattggcagc agcttttgcg
    32641 aaagaaagtt catatagtta ttcattcata gctccttaaa acaatcataa aacagctaag
    32701 atagagcagt aaaggctctc tctaacagct tagccttcat ttttagtttg ctcgctcgcc
    32761 tgccatcttc tttccacatt aataataaac ggcaagtaaa gaagaatatc tagaataatt
    32821 aaaacaagct gtaggactga ggcttgccag ctgcccgttg ccaaaaatcc tgaaataaca
    32881 ggcggcatgg tccaccccgg atcagcatag gtgccaggta caatgccaga agcaaaggca
    32941 aaataagcga caaacaaatt cataacaggt gctagtacaa aaggaataac tgtcaataga
    33001 tttaaaacaa ccggtaagcc aaacatggtc ggctcgttaa tgttgaaaaa ccctggaatc
    33061 aaggtcaatg gtgacaagac ctttgcctgc tgactagcct tgcgacgacg tgctaaccag
    33121 gctaaagcca acaccaagcc aatggttgca ccagctccgc cgataaaaac aaagttatcc
    33181 ataaagacag acgtaaagac atgcggcaat tcctgaccag ccttatgagc tgccatattt
    33241 tcagtcaagt tagataacca gatcggcttc ataataggat tgtttaggac atttccacca
    33301 tgcacaccac agaaccataa aaagccatta agaagaacaa cgataaaatt accaaataag
    33361 gtacttccca gcaagccaaa tggaactcct agtacggact taacaatgtc atggacattt
    33421 ggcaggctaa aatgatccaa gaaagcataa acagcaagcc aaaacacaat aatcaccgct
    33481 ccaggaataa tggcgctaaa gctttttgat actgcaggcg gcacaccctc aggcatctta
    33541 atccgaatat cctttttcat aaaccattga taagcatagc catttaccaa tcccaaaaca
    33601 atggcaacaa acaagccgcc tgatgaaagg taagaaggcg caatacccgc tacctcaccc
    33661 aaggctttac cagattcatt gacaaatgaa acagtaaatg gggtcactgt taaaaaggca
    33721 gagatattaa taatcccagc agaaatcccg tctgccttat actgcttagc caagctataa
    33781 gaaatcccaa aggccgcaac caaggcaatc agattaaagc tcgaatctac tcccttccac
    33841 agataggtag agacaccaat ctcaccaagc caagcttccc aaccaggaat cggcaggcta
    33901 gcaatcacca ttaaaaagga cccaatcaaa atcaagggca tagcgtaggt gatcccatca
    33961 cgaatagcaa taagaaagcg attgcttcct aggcgaccag caactggaac aagcttttgc
    34021 tggataaaat cttcaaattt agtcattgtt acctccttgt gacgttaacc tttcataaat
    34081 agatactagc tcccttgcca aatcaacaaa ggtaatacta gtcatcaaat gatcctgacc
    34141 atgaactaat agtaggctta ctggtgtagc atttccccgt gcctcttgag ttagcatatc
    34201 tgtttgtgca tgatgggcct gcaccaatgc cttatcggcc tgctttagac tttcctgagc
    34261 ttgattgagc tctccctttt tagcaaaagc aatcgcctcc atcgcaagcg acttggcact
    34321 accaccatgc atgatcaggc ccataatcgt ctctagctgc ttatcttcca tgaccaccac
    34381 ctatttcatc aaactttcag ctaaggcaat aaccttatca ccattcatca taccgtaatc
    34441 aaccattggc acaaccgcca ctggaatgtc cttttctgcc aagctttctt gaaatgctga
    34501 caattgataa gcaacctgtg gccctaataa caccacatca acaggatggc ttagagcgta
    34561 atcctctgcc tcagtcaatg gcaatgcaaa aatatctgcc tcaagccccc gattgtcagc
    34621 agccttttcc atctttgtca ctaatagact ggtactcata cccgctgcac aggccaacat
    34681 aatttgtttt ttactcatga tcttctcctt tatcccaaat cctaacgtcg aatagagcgc
    34741 gacattctca caatggtatg tctttttcct cggatagcgt cactaagagc aaagatattt
    34801 tccactggcg caatcccgct atagccagca tctccgatat gatgaatatc gacaccacag
    34861 attttattgc gaatagcaat gtctcgaacg atcgtagtat ctgacccttc ctgactcgtt
    34921 ccaatagctg acataactag agcatcgtga gcatgcacct cctcaacaat agctctaagg
    34981 tcaccctctg taaagccagg aactgtccca acagcaggaa ctaaaatcac atcagcccca
    35041 gcctcgataa accgccgaac agtttctaag tcaatcaccg cttcattaga gccagcagca
    35101 tgcatctttc cagcaataat caagcctgaa aaatagtgct tggcctgttg aatagctctt
    35161 tcaatctgat tattgctaac accagtacct ggatttcctg tcaagcaaac aaagtcaaag
    35221 cccaaggctt caatctcttg aaaggtctta gctgtcgcct gtcgcccttc tactagctcc
    35281 aagcgctttt cagtcatgtc aacgtccaaa tcaattggtt ctaaattaac accaattgga
    35341 cgccccacca gacgacgcag ctctaaaata ggctgatcag tagcaggtag accagatatt
    35401 tgaacatcaa agacatctac acaattcagc aaaatcaaat cagcactaaa ggctgcggca
    35461 acctcagcgt tcgtaaggtc atctccagtc caagagggtc ttggcgctac attttctgag
    35521 acaatggtac gtccctcgct tgccttaatg gcttgcttta gctctaacga tgttaactgt
    35581 agcatttctg agctactagc actcaataat cgtgttttca tcgcttctcc tttattttta
    35641 ttttaaaaac attaacaaaa gataaataag atttaactct tatttgttta ctttttataa
    35701 acaaataaag tatattctat ttaccaatat ttgtcaacgt tttcaggcag gatttttaat
    35761 tcttttttgg tatgatagag gtacgataat agaggttact atgaagacgg ataaacaaca
    35821 agagctttac gcaaaaattt tagataccat ttatgcccaa cggcctattt cacgcattga
    35881 tatttcaaag ctaacgcaca tcacacctgc tacagtaggg gctatcacta aagagctgct
    35941 agcacagggg tggatacacg aaatcggaga gctgacggac cactccgttg gccgcaaaaa
    36001 aatattactt gatgcttcgg ctaacgcctt ttattttgct ggtgtcgaat tgtccgaaaa
    36061 gcatttctat ttggtcatta cagataacct gggcaccatc tatgccaagc acaaccaaca
    36121 gatcgaccca agcatttcct cctactacaa agcagactat atctctgagc tgattcaagc
    36181 cttcctcaag cagcacaagc actatgatgt acaagccata ggaatagcac tgcctgggca
    36241 ttacgatcat tccacctcca gctcaacgca tattaacacc aacaatccca tctggcagca
    36301 ggtcgattta accgcaattg cgaagtcctt ccctattcca gtggtcttta gcaacaatgc
    36361 tcactgtatg attattgcca agcgcttata cgagcgtcag gcacataatc acaattttat
    36421 tttctttcat gtcggacgag gcatgcactg ctcctatatg tataaggggg tcatttatag
    36481 ccgtcacaat gctgttgttg gggaaatcgg acataccatt gtcaacccca ctggagagct
    36541 ttgtgaatgt ggcaaaaaag gctgtttaca gacctatgcc agcaatgcct ggttgctcaa
    36601 aaaagcaaaa ctgctacatc agtatgcccc caattctcat ctaagaagcc ttgtcgataa
    36661 ggcctgtgag ctcaagctag accatctctt gattgcctat gagcttggtg atgtcggggt
    36721 gaccacgctc attcacacag ctattgatta ccttgtttta tccctgtcta acctctcctt
    36781 actgattgat accgagcaaa tctatctcca tggcagattt atcagccatc ctcttatatc
    36841 ctccaaaatt ctgcaagccc tgcaaaatga cattaagctt cttagcaatc aaaaaaagcc
    36901 agaaatcatt gtcatgcctt tttctgtcta taatgccgct gtgggagcta caggcttatg
    36961 tatagatgag ctttacctca attataaaaa caaatatgat tgataacccc cacaccaata
    37021 tcagctaaag ctttaaagcc catttgagaa gctatttctc aagtgggctt ttgcattatg
    37081 cgactttcag tccatctcgc tccgcaggtg cgagacaaat gataaccata aaaaaagaga
    37141 ggcacttggt tctctctgtt ctatcctaat gccccatttg aaactcacca gcaaaatact
    37201 ctgccagcat cagtctatgc ttgtctgaga ttgaagacag ctctgcaatc tcttctctag
    37261 aaaaataacc gagccttaag gtttcatcat tttgataatc agtgatagcc ttatctgcct
    37321 tggctataac ctcataaagc atcacaacgg tctgaacctt atcaccattt ggataggtct
    37381 cttcaaaatt ggtataaaca ttcaacaacc gtaaaggctc tactgtaatc cccgtctcct
    37441 cataaaattc acgcctgcag gtttcagcag aagactcacc cagctccatg gcacctcccg
    37501 gaattgccca ggttttctta tctgcacgta gctgcaaaag caccttacct tcggcattgg
    37561 ccaaaatacc accagcaaaa gtcagaataa tgttatcatg ccccaccttt gagcgaatat
    37621 aggaaatata gtcctgtgtc atcgtaactc ccttcattgc catcataaga ttaaagccag
    37681 tcagctggcg caattgctgc ttttttgcca accaataagc aatgcaggct ttgtctcttg
    37741 tccttgatag gctggcaaag catatagccc taatttttca acctgattat atcacacttt
    37801 ttaaaagcca gaaagagact cgaatgccaa gtcccttttc tttcaatcta taaccaacct
    37861 cagaaaaact cagacaagct acgataactt ttttaatgtc ttctttggcc aatggtttgc
    37921 gactggtcat tgaattactt tcaatattat ccccatcatc acatgataac cacaaataaa
    37981 cacgtacttg tgtcattgcc ttctcctcaa tcagtagtag gtacctactg tttttttgat
    38041 tgattgtacc tataggtgtt tttttccttc aaaatcttta aataaaatac cctttataa
//
LOCUS       DARYVE010000015        37945 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYVE010000015 DARYVE010000000
VERSION     DARYVE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37945
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(80..1285)
                     /locus_tag="TVW25_000688"
     CDS             complement(80..1285)
                     /locus_tag="TVW25_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1378343.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TVW25_000689"
     CDS             complement(1538..2791)
                     /locus_tag="TVW25_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1378344.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TVW25_000690"
     CDS             complement(3188..3808)
                     /locus_tag="TVW25_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378345.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TVW25_000691"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TVW25_000691"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TVW25_000692"
     CDS             4121..5347
                     /locus_tag="TVW25_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1378346.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TVW25_000693"
     CDS             complement(5457..5951)
                     /locus_tag="TVW25_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1378347.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TVW25_000694"
     CDS             complement(5948..6730)
                     /locus_tag="TVW25_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1378348.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TVW25_000695"
     CDS             complement(6829..7368)
                     /locus_tag="TVW25_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1378349.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TVW25_000696"
     CDS             complement(7372..7683)
                     /locus_tag="TVW25_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378350.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TVW25_000697"
     CDS             complement(8070..8207)
                     /locus_tag="TVW25_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1378351.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TVW25_000698"
     CDS             complement(8591..9835)
                     /locus_tag="TVW25_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378352.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TVW25_000699"
     CDS             complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TVW25_000699"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1378353.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11812..12657
                     /locus_tag="TVW25_000700"
     CDS             11812..12657
                     /locus_tag="TVW25_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1378354.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12853..16815)
                     /locus_tag="TVW25_000701"
     CDS             complement(12853..16815)
                     /locus_tag="TVW25_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1378355.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16950..18794)
                     /locus_tag="TVW25_000702"
     CDS             complement(16950..18794)
                     /locus_tag="TVW25_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1378356.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAK
                     KEDKKAADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19154..19627)
                     /gene="perR"
                     /locus_tag="TVW25_000703"
     CDS             complement(19154..19627)
                     /gene="perR"
                     /locus_tag="TVW25_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1378357.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19664..20116)
                     /locus_tag="TVW25_000704"
     CDS             complement(19664..20116)
                     /locus_tag="TVW25_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1378358.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20356..22998)
                     /gene="polA"
                     /locus_tag="TVW25_000705"
     CDS             complement(20356..22998)
                     /gene="polA"
                     /locus_tag="TVW25_000705"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1378359.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23422..25152)
                     /locus_tag="TVW25_000706"
     CDS             complement(23422..25152)
                     /locus_tag="TVW25_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1378360.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25170..26366)
                     /locus_tag="TVW25_000707"
     CDS             complement(25170..26366)
                     /locus_tag="TVW25_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1378361.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26565..26807)
                     /locus_tag="TVW25_000708"
     CDS             complement(26565..26807)
                     /locus_tag="TVW25_000708"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378362.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26872..27963)
                     /gene="ulaG"
                     /locus_tag="TVW25_000709"
     CDS             complement(26872..27963)
                     /gene="ulaG"
                     /locus_tag="TVW25_000709"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1378363.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28158..29804)
                     /locus_tag="TVW25_000710"
     CDS             complement(28158..29804)
                     /locus_tag="TVW25_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1378364.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30108..30824)
                     /locus_tag="TVW25_000711"
     CDS             complement(30108..30824)
                     /locus_tag="TVW25_000711"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1378365.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30824..31687)
                     /locus_tag="TVW25_000712"
     CDS             complement(30824..31687)
                     /locus_tag="TVW25_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1378366.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31692..32357)
                     /locus_tag="TVW25_000713"
     CDS             complement(31692..32357)
                     /locus_tag="TVW25_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1378367.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32452..32937)
                     /locus_tag="TVW25_000714"
     CDS             complement(32452..32937)
                     /locus_tag="TVW25_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1378368.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33153..33431)
                     /locus_tag="TVW25_000715"
     CDS             complement(33153..33431)
                     /locus_tag="TVW25_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1378369.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33546..34979)
                     /locus_tag="TVW25_000716"
     CDS             complement(33546..34979)
                     /locus_tag="TVW25_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1378370.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35462..36082)
                     /locus_tag="TVW25_000717"
                     /pseudo
     CDS             complement(35462..36082)
                     /locus_tag="TVW25_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36084..36701)
                     /locus_tag="TVW25_000718"
     CDS             complement(36084..36701)
                     /locus_tag="TVW25_000718"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378371.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36688..37476)
                     /locus_tag="TVW25_000719"
     CDS             complement(36688..37476)
                     /locus_tag="TVW25_000719"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378372.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37547..37933)
                     /locus_tag="TVW25_000720"
     CDS             complement(37547..37933)
                     /locus_tag="TVW25_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378373.1"
                     /translation="MKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGRTKDYL
                     VKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDTKSGYL
                     YALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        10942 a         8896 c         7417 g        10690 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgatcctc tcttgcgctt
     2821 tgtattttgc ctttaaacgc taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaaa caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc caaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatcg cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt ttttttgatg
    10141 tctgatgact tttaaaaaaa gccttctttt gataggcaag cttaaaaggc ctaggcaaaa
    10201 gcccagaccc ttgctgctat tatctgttat tgtggaaagc taccgctctt tggcactgtc
    10261 atgcttaaaa attgcgactt gagctattgt aaccatagcg ctcaaggaaa tcctgacgaa
    10321 actctaaaag gttatcgtcc aagatagctt gacgcacctg cttcatgagg tttactaaga
    10381 agtataggtt atggtaactg gtcaagcgca tgccaaaggt ctcatcagcc tttaagagat
    10441 gacgcaggta agcacgtgtg taatgctgac aggtgtagca gtcacaatga tggtcaagtg
    10501 gggtaaagtc ctctgcaaac ttagcatttt tcacaacgag acggccctcg ctggtcatgc
    10561 aggtgccatt gcgagcgata cgggttggca ggacgcagtc aaacatgtca accccacgaa
    10621 tcaccccatc aatcaggcta tcaggtgcac ctacccccat caggtagcgt ggcttatttt
    10681 caggtaaaag tggcgttgta aaatcaagga cagcattcat ctcagcatgg ctctcaccaa
    10741 ctgccaagcc accgatagaa tagcccggaa aatccatgct cacaaggtcc gcagcagatt
    10801 gacgacgcag gtcctcaaag ccagctccct gcacgatacc aaagaggcct tgatcatgag
    10861 gacggcggtg agccttcaag ccacgctctg cccaacgact ggtgcgctca atggattttt
    10921 tcacataatc atagggctgg taaaattgcg ggcactcatc aaagctcatc ataatgtcag
    10981 accctaggtt attttgaatg gagatcgctt tctctggtga taaaaacatc tttgagccat
    11041 tcaggtgatt tttaaaggtc accccctcct cagtgatgtt tctggagtct gccaaggaat
    11101 aaacctgaaa gccgcctgag tctgtcagaa ttgcctgatc ccagttcata aatttgtgaa
    11161 ggccgcctgc acgcgcaatc agctcatctc ctggtcgtag ccataggtga taggtatttg
    11221 acaaaataat gcctgaccca atctccttga gctcctcagg agactgtgtc ttaaccgtcg
    11281 cctgtgtccc taccggcata aacatgggcg tcggaaaggt cccatgcggg gtaataatct
    11341 caccgagacg agcacctgta tgcttttcct ttttgatcaa acgataagta atagggtaat
    11401 tagtcattgt ttcttttttc cttgctatca agataaacag tcttgagcgt tttgcatacc
    11461 acttacaaag cacttagtca agcggtatgg gcttgtttag agccctatca ttttatcaaa
    11521 aaatctctga cttgtcatgc cttcaaagag acaagatccc gaagcaatgg cacgacagac
    11581 gcatgaagga gttttagcaa gaaaagaaag ctttctgtcg ttcaatgttc agctatttca
    11641 agtatatgtc ttatctttta taaactttac tacagaaaaa tcgttgaaaa tgtttgcttt
    11701 actctatact atcattcaga aatagctgtt tcgcgcgttt gtcgtgagca aggacggtat
    11761 gggtatcact ggctcctaga atatggtata atgtaccaaa ggagttgtac gatgtcaatt
    11821 agagaaataa aacgtgaagc tagacagact ttaaagggac taaaggggaa atacctctta
    11881 tttttagtac cgataatctt atctattttt tactcaggaa ttgaggttca tcagacctat
    11941 gtgaccactc aggggattga ggtatcagtc ggggcaagct actttccttt gattgttctg
    12001 ataatgctga cggtctttac cttatcagca gcctatacca tgctagatgt tatccgctac
    12061 tatcgtcgtg aggtctcttt ttcagaggca acgatagctt tttctggaaa cttgtttggc
    12121 aaggtccttg ttttgttgat catcaaaggg ctcctattta tcctatggtc tttgatttgg
    12181 attgttggct tggttattct aacgattagc tctgcggcat tactgacaag ctacaatact
    12241 ggtgctgctg tgatgactcc aatcatcttt atggttattg gttttgtgat ttttattatc
    12301 gggcttattg tttatatgaa tcgttattgt gcttacagca tggctgagta cattctctat
    12361 gacaaggtca aggaaggcac ctatatgggt gctattacgg caatcgaaga gagcaaggac
    12421 atgatctcag gctataaagg aaagtatttt ttactacacc ttagctttat tggctggttt
    12481 atcctagtaa tcttgtcttt tggcttgatc tatatctacg tactgcctta ttacaccact
    12541 gctgatgtga ccttttacca ccatttaaag cacattcacg atgaaacaga gctgccgata
    12601 gatgctgaaa ggcttactat cacaggttca aaagaagccc catctgctat tagctagcct
    12661 taacgatatg cctctatgtc tctcatgacc ttgttcagag tagacataga ggttttttgc
    12721 atgacctttg ataacttttt tatagtaaaa aagaggagcc catcagttgc ctatccaaag
    12781 ctagatgaca catctaacgg ttggaaggct tgcttacagg ccctctttta gcaatgttag
    12841 cccaagacta tcctaaagct gctgaaaagc tcctcggtct aaggcatagg cagtcgtcca
    12901 atggctctca cgatagtaaa taaagagctg gctatctaat agctcatcaa ttgaggctgc
    12961 tgttggcaga cctgctaggt caatgaaata atcccctgga agaagctgtt gtagcttttc
    13021 cattaaggcg gtattaacag cggtctttgc tgctggtaat tgactagaga ttgataagcc
    13081 ttcaaaggtc tttaaatcta tgttttctga ctctaaagct gattttaagg ctgatttgat
    13141 caagtctagg ctgtattcag catctaaggc ttcatcgcct gatgagaggc tattcatcgc
    13201 caatacatac aaagggcctg ctgccttatc ctgataggta atgacaagtt gatggttcag
    13261 caaatcagct aagtcatcat aagtaccagt gttctcaaga gtaatgtaat aagtccctgt
    13321 gagccctaag tccttgattg tctctaaaat cttgccttgg attgcttgat ttttttcagt
    13381 tgttgccgct gttagaccac tatttgtaat agcaaagctc tcaatctctt tggtagctgt
    13441 attggtctct tttagaatgg ttagaatact atctttaagc gctagaatat catttctaac
    13501 cggtgcttca atagggctag agatgtcttc aaagaaacga taagcagaac cgctgacaaa
    13561 tttattggcc tgtccgctgc tttttccata ggtgtctaag gcagttattc taacaaatcg
    13621 acctgttgtt ggtgtaaagc tgactgtttt tagctcagta ttttgcttcc aatcagtgct
    13681 atcgacaacc gttgtccaga ccttaccgtc tgagctgatg tcgacctttg cagaatggat
    13741 cataccatta acacctcctg ggagataggc aatagcagag aagtttttat cgtccttaaa
    13801 ctcaacagta tatgacttgt cctcagtaac ctgattaaat aaggtatgcc attgggtggc
    13861 catatctcta ccatctacca tatgcttgcc agacctgcct gattgctcat tagcataggt
    13921 caccgcctga atatcatcaa ttgagatgta gtgcattgta ggatcagtgc tgtctgcggt
    13981 aaaggtatag gtaacgctgt cacttgctag actggtgcca tgagcccgat agcgagcaag
    14041 aactgtgaca gtgtcattga agcgctctgt gccatcataa gcctgccaag actggccatt
    14101 atccagactg acctccaaat gttcaatagc accaatcaag cgattttcca agtcattgcc
    14161 ataaaggctg ctgttggtcg gtgctgctgc ctttgtcagg ttaatcctgt aggtagcaga
    14221 taccgcgtca aagccaacta aaataccgtc ctctatatta agcttggcca aaaggtcatc
    14281 actaaaaacg ataaccttgt ccttggtttc aagccatgtt ttcccattat caatagaata
    14341 gcggactgtc aaatctgtat cctgataatt ctcatgcaaa cgaagggtct tgtcatcaaa
    14401 gctaaagctt gctgtttcga ttggattgcc cgttaggata tagttggcga taattctaac
    14461 ctcattagat tggagcactt ccttatcagt tgctgttttg gctgcgatta gagcgttata
    14521 gctcagtaaa tctagctcag ccttagctgc ttgatcgctg atattaggcg tgatacgctt
    14581 gatagcctct accatgacct gtggatagta ggtgtaagct gcaatgacac gctttcctaa
    14641 gtccagccaa tcctgatctg ttttttggcc attttttgca taggcctcta tcaagccatc
    14701 gtaagtatct agattaagct ctagtacatc taaagccttg ctgtaggcct caatctgttg
    14761 atcactgcca gcctcgtaga cattagcgat gagattataa taaagcgatt ccttgaactt
    14821 atcgtattgg tttaaggctg cttgcgccag cagcatatag ctagcgtttt tatgaatgtc
    14881 attgtaggat tttaggcccc agccaagcaa gagcctagcc tctgttgctg ttgtggttcc
    14941 ccaacgagaa taagagattg cccagcgatt accataaaca ttgtctctaa tatcccaaat
    15001 cccgttgccc tgatcatctt gacggtaaac caaataagcc tcgtggtcat tttggtaaat
    15061 attgaccgct ggaataccaa agacctcatt gactgctaca cctaaatttg ataatcccca
    15121 gcaaacagcc cctttttcca tcagcatcca gatccggtga cggttgtcat aagtaacatt
    15181 aaaggcatcg tcattgaggg tgccaacgag ctgatatttt tctgtccatt gagcttgatt
    15241 gtcagcgctg cgcatgtctg cgccaccgta gccgatgttt ttgtatttcg tataagagta
    15301 gccactggta tagctagcaa ccttatctcc atatttttgt tcggcgtaat gatgcagcca
    15361 gagaatttcc tcatcatcta ttttggcgtc cataacagca cgcaccaact ccatattgta
    15421 gttggcgaat tcttctttcc tcaagaattc gttgtctcga tacaattctt taaaggcttg
    15481 atatttcagc accgggtcag aagcaaggta ggtgccacca tagttaacca caaaggattt
    15541 gatctccttg cagtaggcaa cagcagttgc cagcatcatt tttttgtaga catagccatt
    15601 tcccttgtcc tccaaatctg ccttattagt agcataaagg tctcctaagg cgttcaaggt
    15661 ttttagggta gagccgttaa acatcgagcc tgcctctaaa aacagtgaca gagcgtcctc
    15721 atctgacaat agccaatcaa gagcgacctt gaccttttca tttttcttga cagcagattg
    15781 aatggtgtgg tagccgacac gattgacaaa ttcgcgctca agcactaatg ccaaattgtc
    15841 tggattatca taattatctg tgacactatt cttgctgaga agggcatcat actcttcagt
    15901 tgtctttagc ctgtcataag acacctcgct tgataaatca taatctgtct tgagcaacct
    15961 gagatccgca taaacagagt gatcattacc gttatttttt agtgaatttg caattagctt
    16021 tacatattta gcacctgtaa tatctagatc aacataaaca gcctcactgg ttccggttac
    16081 tgtaccagtt gtcaccaggc tttcccaact ttttccgtcc ttagacttat agatgttaaa
    16141 gctaacacca tcgtccttac cacgtctact atagtcaact cctaggtagg ctgatagacg
    16201 cgtgtattca ttggagtatt gttcaacatc ataataaagc tgtgaaggag catgcactgc
    16261 aattccctta tcaaatgcaa gcacctcgcc atcaactact agagtaatgg tgccaccggc
    16321 agggtttttg tcctgtaaaa agctgccatg cccaaccttg gacgggttga cacgtgtctc
    16381 atctgataag tagatatagt ccttagcttc agtcttattg gtggtctcta ctgcttgtga
    16441 tacttctgtc tgctcctgct ttgtggtctc ttcggcagaa gcttcggtag cttgctctgc
    16501 tgcggctact tgactcttag agtcagttgt ttctgtagtg gcagtaccta ttactactgg
    16561 cagcgtttct gaggagccct cagctgctgt gtcttgcgca gcggttgctg attggtcagc
    16621 tgcttgttga tcaaccgctt cttgtgcttc taacgtggtt gctatggctg cactagctgt
    16681 tacttgctgc tcatcagcag aaacagttgt cagccctagt gttaaaaata aggttgcaac
    16741 caacacagag gctgcacctg ttttaaaggt tttaatggca aagcgctgct taccatcagt
    16801 ataaggtttg aacatggtgt cttctccttt aaaaataaga tatttaagca aaataaagac
    16861 tgaccaccaa ccactacagt tgataatcag tccaacaaag atatcgtact ataggaaatt
    16921 aattaaaggg ggaaaatcat cgcctacagt taatttgatt ctttgcgtct tgacacaata
    16981 gcaagctggc ctgcacaagc aataactgca agagctgctg ctgtaaagaa tggattagct
    17041 gtatcagcag ttgccggaag cacttgctgc ttatcagctg ctttcttgtc ctccttctta
    17101 gcttcaggct tagattctgg tttaggctct ggcttaacct caggatctga tggttttact
    17161 ggatccgctg ggtcgattgg atcgaccggg tctaccggat ccactgggtc taccggatcc
    17221 actgggtcta ctgggtctac tggatccact gggtctactg ggtctactgg atccactggg
    17281 tctaccggat ccactgggtc taccggatct actgggtcta ccggatccac tgggtctact
    17341 ggatctactg gatcgaccgg tttagcaacc aaggctgcct tggcatctga gagggatttc
    17401 ttagcattta acaccttaac caagctgtta gtaatagctg tcggttctgt ctcctgagca
    17461 taagctgtct cacccgctgc tgcgacctcc ttagccttag ctagctggtc tgtataggct
    17521 tgagcagaag ctgctgtata tggagatagg tctagatttt ctccgataag agcatttaat
    17581 tggtctaaag cagaacgcaa ttttgccttt ccttcttcgg caatcgcagc ctttaccttt
    17641 aaaatagtat caacaactga atttgtttct gtagtgtagc gctctagctc ataaagggaa
    17701 atgtcttttc tctctttatc cttgttaaca gttctataga aggtacctgc tgcttcaatg
    17761 gccttattgt acaattcctt caaagactct gatgtcaaag caagatttgg attttctcgg
    17821 taaagctcta acagcttagc caaggcttga tctaaggctt catgcgctac agcagtctta
    17881 agcgtcgtaa gagcttgcgt taaatcagtc gcagccttat caacatctcc ttgtgaagga
    17941 ccaaatgaat tttgaagctt agctgccgct gcaagctttt gcacaagacc gtcatacgct
    18001 tctttaggat actctttgcc atctgttata aaaggtgtag cttgattaat agcttcattt
    18061 aaagcattaa gattaacaag actagtaata gcggaatcaa tagtagtaac agattgatct
    18121 actgtatttt gatcagggtc actgtttaaa taggtcttac caatagtaac cgctgattgc
    18181 aaggcttgca gtgattcatc agaatacgtt ccttcaggct ggctgagttt tagcttagcc
    18241 tcctctaacg acttccttaa ctcagtttta ttgctgttgg aattttttag tttaaatgtg
    18301 aagagctttt tggtatcatt tttcccatag aatacccaag ctttaatagt ataagatccc
    18361 cccggtacag catatgtagg cgaagctaac atttcatcag ttaaaaagga agtacccgca
    18421 gcattgtaaa agtcaaacca tatttttact ccaggggtat caattcctct tgaaccatct
    18481 ccattcgaaa taaagtcaaa agtatctcca tcattaacag tcccattact acctttacga
    18541 gtaaccgtaa tttgactcat aagatctgag atagtaattg gttctcctaa ttcaactgta
    18601 tattcttgtg gaatatctat gtgccagttc agatgttgac ctgtcccatt attttcaaat
    18661 gcactagcag tagtcgtttc cgcccctact gttaaagcgc tatcaatatt atccgacaag
    18721 gcaaccaatc ctgtgctgaa aactaatcca acaagaccac agcccttaag acaccgtttc
    18781 gtgaatttct tcattcttct ttttcctttt ctagagccct agcaggctcg aacaatagca
    18841 atatgtgtca tagggcagct gctatcacta gtagctgcca ctttgatatt agcctgattg
    18901 tgacactcaa atatcactta taatttacaa aaaattttaa gaaaagtcaa tatacaaacg
    18961 gtttttgtta aattttttaa aaatataaca aaaaacaagc acgccaatct ggtctataac
    19021 agtttttatt gtcaatagtg atcgctaaag ggtttttcag ccaacaaaaa aagagtgaat
    19081 ccctaactct ctcttctaga ctttgtgcca tatcatcagc tacacgaaca gccaagatca
    19141 aaaaggccag ctctcaatag tctgtgtcct taccctgctt cgtctgacag ctagggcaaa
    19201 caccataggc tataactgga atacgggtga ccttatagcc tgtttgctgg tgtgcttcct
    19261 tagcgatatc catcacatct acgtccataa aatcagcgat tgtcccgcaa acctcacaaa
    19321 ccacattgac atgctgatgt cccataaagt cataataggt cgtcaaatca ttactaattt
    19381 tcagctcgga tacaaagccc tcatcaacga gaaccttcaa attattatac accgtagcaa
    19441 ggctcatatt agggtattga ggctgtaaat cacgatagat tttatctgcg ctggggtgct
    19501 cagtggactg aatcatgtaa gaaatgatcg ccttacgcgt ctcggtaata cgaatatgct
    19561 tgtcacgtag atgctctagg acattttcat aggcatttag agcttgctga tgtgaatgaa
    19621 tgtccaagct tacaacctcc tccttttgta actatggcac taactagcag gaatcttgat
    19681 cctgcttgct gattagccgt aaatagtcaa tcttgataca gcgattcata acaatgtcag
    19741 ctttgcctgc tgatcgcaaa agctcctcag cttcttggct atacaagcca agctgtgccc
    19801 aaaagacctg accctgacaa gctaaaaagt cctgagcaac ctgaggcaaa tactcacttc
    19861 gtcgaaagac attggcaata tctaccttaa aaggaatagc cgcaaggcta gcataaacga
    19921 cctctcctaa aacagactga cctgccagcc taggattgac agggacaatc cgatagccct
    19981 tagcctgcat aaacctagcc acatcataag cagcagtggt ttgacgatca gataagccaa
    20041 ccactgcaat ggtcttggaa gattcaagat aagaggtgat agtctcatca gagggatttt
    20101 gaaatgtatc aatcatcatt tacttccttt ttatcaagca cacccaatag caaatcaaca
    20161 acaggaaaag acaatcgctg ccggtatgac atagccaacc atctggctac caagctcaag
    20221 gaaaaccctc cttagcatga catgccctgc tgtttttttc tcttcattat agcataagtt
    20281 tttaaaatgc ggaacacaag gaataacagc agccacacca agcaggctgc cacttaacac
    20341 cactgctaat ctagtctact tggcctcata ccagctcttg ccggcacttt cgtctacacg
    20401 cagcggaact gccaggctga cagctgattc catcgtttct ttgaccagcg ctttaacagc
    20461 cgctagctca tgattaggca cctcaagcac aatctcatca tgcacctgaa gcagcatttt
    20521 ggtctcaaag ccaccagcta ctagggcttg gtcaagattt atcatcgcaa ttttgagaat
    20581 atcggctgca ctgccttgaa tgggcgaatt aatggctgta cgctctgcaa aggagcgaac
    20641 gttgaactga cgagaattga tatctggcaa ttgacgacgg cgcttaaaga gcgtctcaac
    20701 atagccctta tccttggctt cacgcacaac cctttccatg taagccttga taccagggta
    20761 gcgctcaaag taggtgtcaa tataagcctt ggcctgtttt cttggaattc caaggttatt
    20821 agacaagcca aagtcagaaa tcccatacac aatgccaaag ttaacagcct tagcattccg
    20881 acgatcattg gcagtgacgt cctctggctt ttcaatgcca aagacacgca ttgccgttga
    20941 ggtatggata tccgctccct ccttaaaagc agcaatcaaa tgctcatctc ctgaaatatg
    21001 tgctaaaaca cgcaattcaa tttgcgaata atccgagcta agcaaaacag catcatcatg
    21061 agatggagta aaggccttac gaatcaagcg cccctgctcc agacgaatcg ggatattttg
    21121 caggttagga tcaacactgg aaagtcggcc tgtctgggtt aaatcctgta aatagcgggt
    21181 gtggatcctg ccatcagcca tgatgtaatc ctgcagtcca atcacatagg ttgattgcag
    21241 cttagtaatt tgacgatagt ccaagatctt agccacgatt ggcgcaattg gcgctaagcg
    21301 ctccaagaca tcaacagccg ttgaatagcc tgtcttggtt ttctttgtca aatgaagagg
    21361 gagctgcatt ttctcaaaga gtatcactcc tagctgcttg ggagaattaa tattaaagac
    21421 ctcaccagcc atttcataga tttcctgtgt cagttcctca atgaccacct tattttgctc
    21481 tgccatttcc tgcaggctat cttgattgac agcaatgcct tcgatttcca ttttcgcaag
    21541 gacattggca agcggcagtt caatgtcagt gtagagatca gcctgctcat gctctgccag
    21601 cttatcaagc atgactggtc tactatccag caagacctga accttacgcg ccagatgtcc
    21661 taacaaaaca gccttgtcag gcacagcacg cttgaccccc ttaccataga caacctcatc
    21721 tgtatccagt gatatagtgg tataaagacg tgccagagta gccatctcat tgtcctctac
    21781 agttgacaag aggtaattag ctaagcgggc atcatagctg gcagccggca aatcaagccc
    21841 cagatgacta agcagaacct tactgcgctt aaaatcatag gtagcaatcg gctgctcaag
    21901 aaccttttta aagagctttg tagtgaggag actaatatct gctgaagcat aaatctggcc
    21961 ttggttgccc caagcaaagc caatcagctc ctcgcggtga taattatccc tcaaagcttc
    22021 aaaataaaac accgtatcgt ctgaaaacat gtccgctctt atgtcagtaa cttcctgata
    22081 agcaatctca gctaccggct cctgtggcaa ctgactagct aaggcatttt ttagttgaac
    22141 aaaatccatc tcatcataaa attgtgacaa gcgatctaga tctggaccct gatagacaat
    22201 atcctccaat ccaatcgtaa tcggagcgct agtgttgata gtagcaagtg tctttgagag
    22261 gaaggcctgc tccttatcat gaagcaggtt ttccttcatt tttgaaggct tgaagctatc
    22321 aatatgctcg taaatcccct ccaagcttcc atattcgtgc aggagcttta gacctgtttt
    22381 ttccccaatt ttggtcactc ctggaatatt atcagacttg tctcccatga gcgctttcaa
    22441 gtcaatgaat tgctctggcg taagccccat tttgtccata aggtaggctg gggtaaactc
    22501 ttcaaattca gcaactcctt ttttagaaat ctcaacaacg gtatttgcat ctgtcagctg
    22561 aatcaaatcc ttgtcaccac tgacaatagt cacatcaaaa ggaatctctg tacgctctgc
    22621 cattttatca agcgttccga taatatcgtc tgcctcgtaa tgctctagct cataaaaggc
    22681 aataccaagc gctcccagca tatcacgaat ataaggaaac tgctcccgaa attcatcagg
    22741 ggtcttggca cgtcctgcct tgtaatcagc aaaaagctct gtccgaaagg ttgttttacc
    22801 cgcgtcaaag gccaccaaga catgcgtcgg ctgaacacgc ttcatcatgt ggtctagcat
    22861 caaatgaaag ccataaatcg cattagtgtg aagaccgctg tgatttttaa agcggtcaat
    22921 ctggttatag agggcaaaaa aggcacgaaa ggccactgag gagccatcaa tcaaaagtaa
    22981 tttattcttg ttttccatgc ctttattata ccacacagtg acctgctttg ctctgaccag
    23041 ctacgctttt tgcaagcact agcaggtaaa gcagcatacc cgtagcttga tcaaaagatc
    23101 caagctgctt gaaggaagat aaatgactgc ttttgcttta tcatcaagac atttctacca
    23161 aaaaagagac tgagataaaa agagtgacac tttagagagt cttaactaat atcctttgtt
    23221 atctaattca ttaacaaacg aacaggccta gttttcaaaa cctcagaaaa ctaaacctgt
    23281 tcatttgttc tatttgaagt cagactttgt ctcaatctcc aaattgatga catcatctgc
    23341 tatgactttc ctaagctgat atggacggaa agccttctgc aaaatccatg attagtctag
    23401 gctacatttg agcgagcggc cttatgactg agtccatttg gccaccttat cagcatggct
    23461 agccacccat ttcttggctg cggcttctgg tgtcatgccc tgattgatgt caagcataac
    23521 agcctccata tcctcttttt cccaatggaa gtgatcaaca atcctatgaa cagctggcag
    23581 gtcggccttt aagccccgac gtgcaatggt attgatattt tcctttgagc caaaggtttt
    23641 ctttggatct gccaggtatt tcaaatcgta cttagcaaac atccaatgag gagaccaagc
    23701 cgtcacaacg atcggctcct ttttcttgac cgcctgatca agtgaggtgg tcatagcacc
    23761 tgtcgaagca gcaacgagct cccaatctgc caagttggaa taggcctttt gcgtcttatc
    23821 agcagcagtc ataataccag ctcccggttc aatcccaata atctgttgat tggcttgatc
    23881 cgaaagctcc tctatgctgt tcacatcgct catataggct ggcacagcga gtcctagctt
    23941 tgttcccttc agattaggac caagattatc cagcttatcc tgatactttt ggtactgctg
    24001 ctgatgggtc actggtaacc aggcacttgt tgaaaagtct gcatcgccat ttgcgatggt
    24061 ttgccacatc acagcattat ccagtggtgt caaggttacc tgataaccct catctcttaa
    24121 gacctgagcg ataacatggg tagaagccac ctcagaatcc cactgcacat aagcaatggt
    24181 caccttctgc cccttgtctg ctgagcttga taacatcgca gcaaagccac gccccaaagc
    24241 tgacaacaaa aagacagcta aagcagctag accaagccat ttcttggttt ttccagtctg
    24301 cgttctttct tgcggcttac cgttaaaatg ctgagtcata cgatccaaaa taatcgccaa
    24361 gataacaagg gccaaaccac taacaaagcc acgcccaata tcagcatgct gcaaggccga
    24421 taggacctca cgtccaagac ctggagcacc aatcattgag cctgtcacaa ccattgatag
    24481 ggccaacatc atggtctgat taacacctgc catcatcgta tgctttgcca agggtaattc
    24541 gaccttcagt aatttttgtt taggggttga cccaaaggca tctgaagctt caaccaattc
    24601 tgtcggaata tgacgaagcg ctaaattggt aaaacgaaca gtcggcggca aggcaaagat
    24661 aaccgacgca aagacgccag ggaccatacc aatgccaaaa aaggcgacag ccggaatcaa
    24721 ataaacaaag gctggcatgg tctgcataag gtccagcatt ggattaatca cctggtgaac
    24781 aatcttattt ttagccatcc aaatgcccaa gggaatacca agcaagacag agatgaggct
    24841 tgctaccaaa accagcgtaa aggtattgat cagctctgcc cacaggcctt ggttatagac
    24901 aaataacagg cccaggaggg taaagatcgg caaaggccat ttttttcttg ccaagaaaaa
    24961 catcgcacag gtaaccaata gcataaacag taacggattg ataaacaaaa gggtctgcgt
    25021 gatccaatcc atcaaagcat tgcccacaag ctgcagcaga tcaaagaagc ctgaaaaggt
    25081 ttttgtcagc cactcagtta gttgctcaac cagctgtgcc actggtagag ttgtttgtaa
    25141 taggttttcc aaaatacagt ctctccattc taattaaggt cgtcatctgg aatattagcc
    25201 aaggcttcaa ggacacgccc acgaataata acccctaaca agcggtgctg ctcatctgtc
    25261 actgcaattg gcgcagaaga gtcataaatc aagggcaaaa tatccgtaat aacagtatcc
    25321 tttgagaccg ttctgacatt acgatcaata acctctgaca aggggagctt tttctgacgt
    25381 gcttcaatcg ctccgtctgc tgttaggctt cctattagct gacgacgacg attggttgcc
    25441 atgagcatag acacctcctc attgtgcata cgattcaaag ccacctgcgg accgtccaga
    25501 tcaaccgttg ttgtgatagg cttaatcata atatgctgag cagtcagcac ctttgagcgg
    25561 tcaacgtcct ctacaaattc acgaacaaaa tcattagccg gattggttag aatatcctca
    25621 cccgtcccaa tctgcatgat ctgaccgtcc ttcatcaagg caatacgatc accaatacgc
    25681 agagcctcat tcaagtcgtg actgataaaa ataatggtct gcttcatcgt ctcctgtaat
    25741 tctagcagct catcttgcat gtcacgacga atcaagggat ctaaggcaga aaaagcctcg
    25801 tccatcagca aaatcttagg gctgtttgcc aaggcacgcg ccaagccaac acgctgctgc
    25861 atgccaccag acaattgatc agggtattgg tccctgacct caagaagccc tgactgatca
    25921 agcgcacgct ttgcaatctc tcgacgctcc tgctttggta ccccacgcag ctccaagcca
    25981 aactctgtgt tttccaaaat cgtcttgtgt ggaaaaagag caaagctttg aaaaaccata
    26041 ttcatatcat gcctgcgaac ttctctgagc tgatccacag acagtttaga aatatccctt
    26101 ccctctaata aaatagagcc tgctgagggc tcaattaatc gattaagcat acgaacaagc
    26161 gttgatttgc cgctgcctga aaggcccatg atcacaaaaa tctcgccttc ctgaacctca
    26221 aagctggcat catagacccc gacagtaact cctgtctttt taaaaatagc gctcttactt
    26281 ttaccagcct tgatcatttc aagagctgct ttttgttttt tgccaaacaa tttactcaaa
    26341 tgcctgacct ctaaaatagt tcccattctt ttcctctctt gttctcttcc tcgattaaag
    26401 ctaaattagc ttaatagatt tctaaaagtg ccaccacaat tttaaaataa tgaggtcact
    26461 ttttgcttaa aaaaagagtc tgcctaaaca gaacacatta attatataat atatggtcac
    26521 tttttgtcaa gctggacgct tgctacccaa gtatcaggat cgtcctaagc agtgatatca
    26581 ctagtcaacc aagcacttaa cagccctgaa cagaccacag caagcaggcc tttctgacac
    26641 ttagcgcctt gagagcttac ccagcagcct cctctagctg acttgattga cctatctgac
    26701 tcttgtcctg caaccaaacc aatgcttaga ctgccaagca agctcccaat agcaataaga
    26761 tctgctaagc aaagcgttag cttgctttga ccatagctgc tagtcatgtc taatagcact
    26821 ctagataaat caaaagcccc acctagcaag gctagatgag gcaaaatagg tttagagaag
    26881 ggctttaaac tgaatatttg agtcttccaa gaagcagtcg tcaaagccac gtgggtgatg
    26941 atactcgatg cgatcctgat cctgtggata ggtgtatttg ccaccaacct cccaaatgaa
    27001 tggatggaat tggtattgca agcgctcctt acgcatcttc caaagctcta ggatttcatc
    27061 agttgaggcc atgaagtttg accagatatc atagtgaacc ggaatgacaa ccttggcgcg
    27121 gagattttct gccatacgaa gtaggtcaac agaggtcatc ttatcctgaa taccgattgg
    27181 attttcacca taattgttca agacaacatc aatatcgtag tcacgtccat gcttagcaaa
    27241 atagtttgag aagtgggagt ctgcaccatg atagatggtt cctcctggtg tttcaaaaat
    27301 gtagttaacg gttttgcgag ctaactcttc gtcagtcact ggaagtcctg ctagctcgcc
    27361 accattttcc tcagcgccag caactggtaa ggtaacgata caggtacggt caaaggattc
    27421 aacagcagta accttgatat ccttgaatgc aaagctatcg cctggtttta ccacgatgat
    27481 acgatccttt ggaacacccc agctctccca aatcttgccg cactcataag ggccaacaaa
    27541 tttgacatgg tcaagctttg gattgttgat aatggctgct gcagtattga tatcaatgtg
    27601 gtcactatga taatgagaca ccaagtaata gtctaactca ttaatcataa agggatcaat
    27661 aaccattggc tgagctctta gatttggttg tagcttgcga acccctgcca tattggccat
    27721 ttggtgacca cgaaccatgt cttttacttt tttagttgcc tttccacgat tggaccatag
    27781 gtccatgaca acattggcac cacccggtgt tttgatccag ataccgcagt tacctagcca
    27841 ccacatagag aaatttcctt caggcactac ctcttcttca atttcttcgt ttagccaggt
    27901 tccccattct gggaaggtgc taagaatcca tgattcacga gttatatctt gtactttagc
    27961 cattatgttt cctccaaaat gaatttttat ctatactcta agtatagacc ttctttattc
    28021 tcataaaaag accaagtgtc acacactctt gtgttcaaaa ctggactgaa ttttggctca
    28081 aaataaacta aaagccccag ccttctccta aaccaataga cagctgaggg gtccttatca
    28141 ataggcaagc tagtagctta caataattcg tgatgaatga gcttttcaat ttttgttttc
    28201 aaggcatagc ggtcagcatc gtccttaaca atggtctcga tcgccttttc tagctcaagg
    28261 gaaaaacgag agctatcact caagcgcccc tgctttgaaa aacggatcaa tctaataatg
    28321 tcatcatcgc tcaaaatagg attgacaatc agtacgggaa caagagcctc cagtgcgtct
    28381 gttgttgata ccacaatgtc aacagacatc aaatcaaaga cactctggta ttgctctgtt
    28441 gtaaagacag cctcgatttg acaattgggc aaataacgct ggcactgctt caacagcagc
    28501 ttttgaatcc caatgccatc atctgaaacg ataacaagct tggtcttgtc ccagtcagca
    28561 tgactatggc gcagctctcc tcccagatga atcgttagat aagccacgtc atcatctgtt
    28621 agacggatct gccaagcctg ctctaggatt acagcacagg attgagccat agcaaagagc
    28681 tcctcgtatt tttccttaat atggtctgtt aaaggattga tcgaaaaaat cccataggcc
    28741 tttcgataaa caagggcctt gcaatgcctg gtcagctgtc taagcaagtc ctttttgtgg
    28801 gtaaaatgca gctgatagcg cagctccagc tgatcgataa aatcaccaat agtggctcgc
    28861 atctgctcat aatcctgact ttcaacatgg tgatcctgat cttttctaaa ggatagcatc
    28921 agcatggcta tcatgcctac ctcaatgtca tctaaatgca gcttgaaatt gtggtaaagc
    28981 tcactagcca atgccttagc aatctggtat tccttgcgct tccaaatcag gttaaaatcc
    29041 cttttaagcg ctgttttagt ttccgaatgc aattgcatgt tgcgatagct aagcaggata
    29101 aaaggaagaa tttgcagcat aaactgacta tcctgaatat taattgtttt gcctaggcta
    29161 gcctgagaca aaaagaggta ttcgtgaaaa taatccaaaa cctcctttga aaaataagct
    29221 gacaagcctt gtgtctcaga aagcttatga tcaaaaagct caataaagct gctattgcct
    29281 ccctgataaa cacctgccaa taccttgtaa aggtactgaa tcaaagccat agggtgacag
    29341 tcaaagtaat agcccttggc cttggtggca tgcagctgaa tcttattgtt atagctagac
    29401 aattcctctc tcagttcagc aaggtcattt aagatggtat ttctggaaac atcattaatc
    29461 atcatgagct tatccagtgt cacccgctct gttgccactg caatataaat cgctgataag
    29521 ctcctgcgct catcaccctt catgacatag tgataatctg ccacttcatt gaggagctgt
    29581 tggcaggcag ccttttgctc actatttagc aagatgccaa cccgaggata ggagacaatt
    29641 tgagcaacat ggctgggcag cgcttcgtta attttatcca aatgataata gattttgcgc
    29701 cgcgactgac ccaaggcagc tgaaatcgcc atgactgtct cagcctcctt caatcgaatc
    29761 agatatgaca gcagatcata gcttttttta tccaaaataa tcacgttcat acctcccttc
    29821 tataaaacat cactaccaca cagccttatc agtttaccat tttacctatc tgtaggaaag
    29881 aatactaggc caaagtcaat ttctaaatag gaaaaaacga acgatcatta gttttctgaa
    29941 gataaaattc ctaattagtt cgcttttttc ttttataatt gtaatagttg aattaattat
    30001 taaactttgt ctaaaataag aggcttttta tcccagattg caacaagggt taacaccttg
    30061 accttaagcc tagctaagca gctctcacta agttactagc tgctgcctta atgccggcta
    30121 cctttttggc cataataggc atttggacca tgctttctaa ggtaatgctt gtccataata
    30181 taggttggag ctggctccac acgaggattg atttgttctg tcaggcggtt catcttggcc
    30241 acctcttcga gcaccactga gtgataaacc gctaattcag gcgtcttgcc ccaagtaaag
    30301 ggaccatgat tgcgaacaac aataccaggc actgccatcg gatcaagacc acgactagca
    30361 aattcctcta aaataaccgt acccgtttct ttttcatagg ctccattaac ctcatcggca
    30421 gttagagagc gagcacatgg aatggggcca taaaagtaat cagcatgagt tgtcccataa
    30481 aatggaatat ctcgcccagc ctgtgcccag ccaaccgctt ctgttgagtg tgtgtgcaca
    30541 atcccgccaa cctctggcca tgccttgtat aattgcacat gggttggcaa atcagaagaa
    30601 gggttcagct ctccctcaac aatagtgcca tctaagtctg taacgaccat attttccggt
    30661 gttaattggt catagtcaac gccgcttggc ttgatgacga tacgtcccag ctcacgacag
    30721 acctctgaga cattgcccca ggtaaatttc accagcccat gcagcggtag ggccttgttg
    30781 gctgcacaga cacgttcacg catttcttgt agcctttttg ccattagctt aaccccgctt
    30841 tctcaatcag tggataaagg aaatcctgtg cctccttgat ggcagctctt gtctcctcta
    30901 cagtttcaca gttttctgac cacatttcaa tcaaaaatgg accatgataa tgcgttttct
    30961 tgagcacatc aaacattgct tcccaatcaa cacagccttg accgaatggc acatcacgaa
    31021 attgcccttt agatgtttct gtcacagcat aggtgtcctt tagatgcaag gcagcaatag
    31081 accgatgccc attgtaaaat tcactccaga ggtcattatg ccaagcagag acattgcccg
    31141 tatctggata gacaaagaga taaggggagt caatttcttt ttccacagct aggtatttct
    31201 caattgagtt gataaaagga tcgtccatta tttcaatggc taaaataacc tgagcttcct
    31261 ctgcccaagt gcaggcctgt ctgagatttt tgataaagcg cgcacgcgtt tcaggtgatt
    31321 tttcttcata ataaacgtca tagccagcca attgaatggt acgcacacca agatcctgtg
    31381 ctagcacaat gcattttttc attagctcta atgatgtcgc ttctgtttct ggattgctag
    31441 agccaagtgg ataacgacga tgaccagaga agcaaatgct tgggatacga acccctgttt
    31501 cataaatagc cttgacaatg tctagtcgct cctgtttact ccaatccaag cgcgctaggc
    31561 gagcatctga ttcatcgaca gacatttcta caaaatcaaa gcctaatacc tttgcaaatt
    31621 gcaagcgttc cagccaagta aaatgctttg gcgttgcttt ttcatatata ccaataggac
    31681 gcgccatatt gttaccccca aatgcgtcga atctcgtctt taaaggcacg tgccgctgct
    31741 gcaggatcct ctgcttcagt gataccacga cctgcaataa aggtaaagac attaacccct
    31801 tcaaagagct tgagggtatt gatatctaag ccacccgtca ccgatacacg aaagcccatg
    31861 tcaatgaggg ctttgacctt gttcagatct ttttcacccc atacttcacc agcgagtagg
    31921 gcgtcacgtg attgatggta aatcgcctgt gaaatgcctg catctagcca caattgtgcc
    31981 tgttcatagg tccaatcacc atacagctca acctgaatct cgccacgttc cccacgctct
    32041 tctttgatgg ctttcagtgc ggctgccatg gttggaatag tggcacagca aatacaagtc
    32101 atccagtccg caccacgctt agcattattc ttagcaacag taccgccagc gtctgcacac
    32161 ttggtgtctg ctacgatgat cttctctgga aataagctac gcagcacctc aaccaattcg
    32221 ctgcctactt gaagcaggca aactgtccct gcttcgatta catcaacctc gtgaccaact
    32281 gcaacagcag ccctgaccgc cccctgcaaa tcagaatgat ctaaggcaac ctgtaatttt
    32341 ggaatatgtg tcatgatttt ctaccaagag cccgtagcac cgccttcaat gcttaatagc
    32401 gagctcctat cctttctgtt gtgtttgatt cgtttagtga tgatggcttg tctaagaatc
    32461 caaatccaag ccctctaaat aaggactatt tttggactcg tccaccaaag ccaaaacctc
    32521 tgctggagtg tgacaggcaa ctaagcgcga aatagcgtct tccagttcaa aaagggcgac
    32581 aatctgtgga atagcaactg ttgtatgaat agaaggatca gttgccgcca aggttagcaa
    32641 taccgaagcc tctttgccat ctgaaaaggt caccggcttg gtcagtgtga taagagcaaa
    32701 ggcatttcgc ttgaccccta caccagcctc tgcgtgtggc atggccattc ccggcataag
    32761 gacataatag ggcccgtact tttctgttga tgcgataata gcgtcataat attcagaggt
    32821 caccgccccg ctgtcaatca aaggctgaac agctagctta accgcttcct gccagctagc
    32881 tgctgacaag cccaagcgaa tagagttgtt ttcgataaat gcttttttta aattcatata
    32941 actatccttt ctaaatcaaa ttctttggcc agacactttt tgcctcactc ctatctagct
    33001 gataaagaga aagagctgga atctctcttc acaactctca ctccatctat ccttactgaa
    33061 agttgattgc tacagcttag cttacagcca agtggctgct cttaggctca ctatcatttg
    33121 ccatgagcag cactgatgtc atcagggccg ctctaaagca ccgcctgtag cttggttttg
    33181 atttcattgt cgtccataag attatctagt ccaaccaaat gaccctttgt acgcccatct
    33241 aattcatgaa tcaggtgatt agaagcaacc acaatatcat agcctgaggc aagtcccttt
    33301 gcctcaccca ctgagcaaga agcagactga atatcagtca ccccaagctg acgaagtgcg
    33361 ttttcaacct tcattttaat aaccattgat gaccccatgc cattaccgca tgctgtaaga
    33421 accttaacca tttattttcc tccgaatata tgataatttg atatgaatga agacctgcag
    33481 aagtatatcg acaaactcct accagcctgt gctaaaagac gaataagcag ctattatcac
    33541 cttgcttatt gtgcttcacc gcggtagtaa gcctctttat ccttagccct agcaaattgt
    33601 agctgtggaa tagcaagtaa gaagacacac accaccacat agcctgcaat accaaggaac
    33661 ttgaagagat aaccaaatgg aagccaagga agcaccaggt caatattgcc atgataacca
    33721 cctgtcaagc ccaacagacc aactgccact gcacctaagg caacctgaag aatacctgat
    33781 ataaaggata gagcaacagc tgccttccag ccaccacgct tatctgcata aacagcaatc
    33841 gcagcattat caaagaagac cggaacaaat cctgtgatga tcaagattgg atttttaaag
    33901 atcacaagaa gtgcaatagt gattagctga ccgataagcc caaaggtaaa tcctgacaaa
    33961 acagcgtttg aagagccaaa gccatatgac gctgcaacgt ccaccgcagg aaatgaaccc
    34021 ggaaggagct tacttgaaat cccttggaag gcattggtca actctgacac aaacatacgc
    34081 acaccctgca tcaggataaa gagataaact gagaaagtta aggaggtttg caaaatatac
    34141 ataaagaagg cctgcttagc tggattaaag gcaccagcac ctataagttc tgcattagac
    34201 atcatatctg ggccaagcac agccaagata gcaccaaaga aaaccagcat tagagtggca
    34261 gaagcaacca ccgtatcatg aaaaatcgtt aaaaagcttg ctagcttaag attgtcaagg
    34321 ttctcttctt ttttaccaaa gaaaggcgcc accttgtcaa caaaccagat cgcaaactgc
    34381 tgctggtgcc caatggcaaa gcctccacca cctgtcaagc gctgagtcgc ctcaactgtc
    34441 atattggagc tgacagccca gtaaaggcca cagataatac cgaccgccca agcaccaaaa
    34501 gcattttgaa gctgagggat taaaagaaga acaaacacag agatggttgc cgcctgctgc
    34561 accatgatat gacccgtaat aaagagcgta cgaacctttg tcaccttacg aagcgccact
    34621 agcaaaatat tgaccccaaa accgatcaaa agggctgtgg tggcaacgct gatggatccc
    34681 atctcctcta gcttggtatt ggctgctgca agtccaaagt aagggtcaat aactgcggcc
    34741 tttaattcaa atttcttacc caatgccact aggattgggc gaaaggtgtt aaccaagccc
    34801 ccagcaccaa cattcaaaat cagataacca accgttgcct taacaaagcc agcaaatact
    34861 tcatgcaggg gctttttaag cagcaaatac ccaatcaaaa ccaaaagacc tacaaagaaa
    34921 gccggatttt gcaaaatatc ttgcgaaaac cagtttaggg gagctataag cattttcata
    34981 agaactacct cttttcacag ttaataaata tgatattttc tatacaataa ttgtaaacga
    35041 tgtaagcgtt taaaaaaaag accaacaatc acacaaagaa gtgttcaaaa atgtactgaa
    35101 gccaatttcc agctagctct gatcactgtt aaagcactat cattaatctc taattaataa
    35161 ccaaacacat cacaacaata tcgggctaac acaaaaatag gccagcccat actgcccagc
    35221 caaaacgaaa caagcaatca attcaaggca cttaaccctg ttttatatcg tacaaagccc
    35281 ttttaagatg attttgtttg tttcctaatc gtaaattagt tatctgatcc gttctctcct
    35341 cagatatact cacccttatc taattctact gtcaaatagc tacttactca taagcaaatg
    35401 aatattaagc aaccaccaag ctacaataaa agaccttacc ctgttggcaa gatcttattc
    35461 attatacaat ttttccttct gcgacatgga ctacctcatc acacaagtct tcaatatctg
    35521 tcttcagatg tgagcttaaa atcacaagcc catttttgct aacatctaaa agcaattttt
    35581 tcgtttgctc cacgctcctg tcatctaatg cattcattgg ctcatctaat ataaggatct
    35641 tagggtgatg catcaaggcc tgaattaacc ctaatttttt cttagtgcct agcgattaat
    35701 gcttaaatgc tgtttgacta aactgatgta aatgataaac atctaaccaa aaagctaaat
    35761 caatatctct agccttagga gagattgacc taagcaactc tagattttgt aacaatgtta
    35821 aatgtgcaat aaactctgga ttctcaatca aaatcccagc atcctcgata taattatggt
    35881 actgtctaat ttttttattg tcctgataaa cagctccttc atctaatttg atataaccag
    35941 ctaaggcctt aagtatcaag gtttttcccg aaccattaat acctaccaaa ccatagatat
    36001 taccttcttt aaaagtaaga ttaatatcat ctagaacaag gttaccctta tacagttttc
    36061 taccatgttc aatccgtaac atctcagctc tccttataat aattgtcata aagcatatgt
    36121 accaatacta ttagcagcag gcaccaccaa acatcaaaca aaaagtaacg tatcaaggtg
    36181 agactagcaa acaagatcat agctactaca gcagatgagg catagcgtat cataacataa
    36241 atcaagcaaa tatctatagt aagccaagat accataagat aacatagtcg ttcaatatga
    36301 tatggtgcac cataataggt catcaataca cctaatatta aaacgataaa aagtaaccac
    36361 tctttaatat agaaaatcgt actcgtccgc catagcttgt taaaaaatac caactgactt
    36421 cgagcatgaa aacgaaagat ttccttagtt ccttcagcca aatccgccaa aaatgaaatc
    36481 gtaaaataaa agctgttgaa ggacaagcct agcaaggtga taaccttgac aaaatcagct
    36541 gtctcccctt caatcactgg aaacggcatt agcaaccgat agcacactaa attatgaaaa
    36601 tctcgctccc cagtcatatt agccttaatc aataaaagat gtattagtaa gccagtaaga
    36661 catgctttca ttccaacaac cagcaggtta gataatttca tggtgcttcc tcaattttaa
    36721 aacgatgcac acacccacta agcctaaata aggtgataaa aggtaaggaa tatcagcatc
    36781 actataagat gttgacatca aagaagtcat aagaacatat ttgggaggta aatagctata
    36841 taacaacggt gacaaagccc acatcaaaat caaatagagc atgcttgact taataaagga
    36901 ttgaagatag tcaacaagaa aacaaacgaa atacgtatga acgaacaaag ctaacgattt
    36961 tactaagcaa tagtaagcta taaaggttgt tgctccttga ccaaaaaaac gcaatattga
    37021 gttttgatca aaataaggca ttaaattacc gttcatatgg gcaacaccat ttagccaaga
    37081 cactaaagtc aaagcaaata ttacaatgta aaaactcagt aaaacatata agctcaactg
    37141 aagctttaaa aaaatacacc ttttaccata gtcagacttt ctgccaatga ggtatttaag
    37201 atgtcttgac ttaaggtaat agtaggcata ggccactaaa atcatcacta gtggatagat
    37261 aaaagattga taaaaactaa aatcaaacac cacactatcc aaacgtatca tactcaacaa
    37321 tagacttttc tttacctcaa ttccaccaga taaatctact gcacttgtat caaaaaataa
    37381 gatatgcttc aaactgtcaa aataaataaa acctaaaaat agtaacggga ctaatggata
    37441 aaaatagcga aatggaaata atctatactg tagcatttat gaataactcc cctacaaaaa
    37501 atcaaggaaa cgcctcgtta ctaactcaat tcacaattgt agatatttac caattgtctg
    37561 gagaccaact accactaatg gttgttgctc cgtcccacca attttcacgt accagatgca
    37621 aggcataaag gtacccactt ttagtatcct gtgtataaat tcctctgtcg cctgtccaag
    37681 ttttatctat atcacttctt ctttgaccgt tactattagc tagatagtgc cttaccacaa
    37741 tttctctatt acgtcctctt gaatctaaat taacgacata ataaggcgcc gcactcttca
    37801 caagataatc tttcgtcctt ccaaaagatg acgtgattct aaaattttgc aagtaaccaa
    37861 tttgtcgttc tgctataact aaagaactaa tcaataatgt agaagctaca attgccaata
    37921 atccaatctt aattttgcct aattt
//
LOCUS       DARYVE010000016        35714 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYVE010000016 DARYVE010000000
VERSION     DARYVE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35714
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..693
                     /locus_tag="TVW25_000721"
     CDS             <1..693
                     /locus_tag="TVW25_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378374.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TVW25_000722"
     CDS             complement(1204..2832)
                     /locus_tag="TVW25_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378375.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TVW25_000723"
     CDS             complement(2837..3568)
                     /locus_tag="TVW25_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378376.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TVW25_000724"
     CDS             complement(3605..3862)
                     /locus_tag="TVW25_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1378377.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4234..5682
                     /locus_tag="TVW25_000725"
     CDS             4234..5682
                     /locus_tag="TVW25_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378378.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQGPRGEKGEQG
                     QRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGENGEQQPKGD
                     QGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQSTPSKKAVL
                     PATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5864..7852)
                     /gene="tkt"
                     /locus_tag="TVW25_000726"
     CDS             complement(5864..7852)
                     /gene="tkt"
                     /locus_tag="TVW25_000726"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1378379.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8236..8880)
                     /gene="fsa"
                     /locus_tag="TVW25_000727"
     CDS             complement(8236..8880)
                     /gene="fsa"
                     /locus_tag="TVW25_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1378380.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9054..10559)
                     /gene="glpK"
                     /locus_tag="TVW25_000728"
     CDS             complement(9054..10559)
                     /gene="glpK"
                     /locus_tag="TVW25_000728"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1378381.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10899..11492)
                     /locus_tag="TVW25_000729"
     CDS             complement(10899..11492)
                     /locus_tag="TVW25_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1378382.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            complement(12160..12360)
                     /locus_tag="TVW25_000730"
     CDS             complement(12160..12360)
                     /locus_tag="TVW25_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1378383.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            complement(12419..12574)
                     /locus_tag="TVW25_000731"
     CDS             complement(12419..12574)
                     /locus_tag="TVW25_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1378384.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            complement(13080..13946)
                     /gene="rsmI"
                     /locus_tag="TVW25_000732"
     CDS             complement(13080..13946)
                     /gene="rsmI"
                     /locus_tag="TVW25_000732"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1378385.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            complement(13951..14274)
                     /gene="yabA"
                     /locus_tag="TVW25_000733"
     CDS             complement(13951..14274)
                     /gene="yabA"
                     /locus_tag="TVW25_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1378386.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            complement(14267..15067)
                     /locus_tag="TVW25_000734"
     CDS             complement(14267..15067)
                     /locus_tag="TVW25_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1378387.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            complement(15064..15939)
                     /locus_tag="TVW25_000735"
     CDS             complement(15064..15939)
                     /locus_tag="TVW25_000735"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1378388.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            complement(15953..16588)
                     /locus_tag="TVW25_000736"
     CDS             complement(15953..16588)
                     /locus_tag="TVW25_000736"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1378389.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            complement(16904..17188)
                     /locus_tag="TVW25_000737"
     CDS             complement(16904..17188)
                     /locus_tag="TVW25_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1378390.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            complement(17189..17635)
                     /locus_tag="TVW25_000738"
     CDS             complement(17189..17635)
                     /locus_tag="TVW25_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1378391.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            complement(17740..18330)
                     /locus_tag="TVW25_000739"
     CDS             complement(17740..18330)
                     /locus_tag="TVW25_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1378392.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            complement(18561..19190)
                     /gene="upp"
                     /locus_tag="TVW25_000740"
     CDS             complement(18561..19190)
                     /gene="upp"
                     /locus_tag="TVW25_000740"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1378393.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            complement(19340..20971)
                     /locus_tag="TVW25_000741"
     CDS             complement(19340..20971)
                     /locus_tag="TVW25_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1378394.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAG
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            21057..22502
                     /locus_tag="TVW25_000742"
     CDS             21057..22502
                     /locus_tag="TVW25_000742"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1378395.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            22762..23541
                     /locus_tag="TVW25_000743"
     CDS             22762..23541
                     /locus_tag="TVW25_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378396.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            23566..24504
                     /locus_tag="TVW25_000744"
     CDS             23566..24504
                     /locus_tag="TVW25_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1378397.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            24514..25539
                     /locus_tag="TVW25_000745"
     CDS             24514..25539
                     /locus_tag="TVW25_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1378398.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            25536..26534
                     /locus_tag="TVW25_000746"
     CDS             25536..26534
                     /locus_tag="TVW25_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1378399.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(26639..27292)
                     /locus_tag="TVW25_000747"
     CDS             complement(26639..27292)
                     /locus_tag="TVW25_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1378400.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(27359..28294)
                     /locus_tag="TVW25_000748"
     CDS             complement(27359..28294)
                     /locus_tag="TVW25_000748"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1378401.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            complement(28794..29585)
                     /gene="pflA"
                     /locus_tag="TVW25_000749"
     CDS             complement(28794..29585)
                     /gene="pflA"
                     /locus_tag="TVW25_000749"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1378402.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            complement(29662..30996)
                     /locus_tag="TVW25_000750"
     CDS             complement(29662..30996)
                     /locus_tag="TVW25_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1378403.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            complement(31124..31681)
                     /locus_tag="TVW25_000751"
     CDS             complement(31124..31681)
                     /locus_tag="TVW25_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1378404.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            complement(31691..32476)
                     /locus_tag="TVW25_000752"
     CDS             complement(31691..32476)
                     /locus_tag="TVW25_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1378405.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            complement(32489..33412)
                     /locus_tag="TVW25_000753"
     CDS             complement(32489..33412)
                     /locus_tag="TVW25_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1378406.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            complement(33603..34253)
                     /locus_tag="TVW25_000754"
     CDS             complement(33603..34253)
                     /locus_tag="TVW25_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1378407.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            complement(34243..34821)
                     /locus_tag="TVW25_000755"
     CDS             complement(34243..34821)
                     /locus_tag="TVW25_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1378408.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     regulatory      complement(34894..35019)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
BASE COUNT        10495 a         8496 c         7080 g         9643 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaaacgaaac tacggagaca aactaatcag
     4141 cagctatttc ttacatttag ctagcgtgtt aagatagcta ttggaaaaga tttttaggaa
     4201 tacttcatat ttctatcatc aaaggagaga gaaatgataa ataaaagaaa gaaaaaactt
     4261 atctacaggt atggtgtctg ctcggcagca gttatcctag cagcgcttgc tagcctagga
     4321 acatgtaaag aagcaaaagc attatctggt ccgccaggat acccacttac tcgtgatttc
     4381 tcccgtaact tcctagaaga aaatactgca aaatatttag atcaattaag agaacatcta
     4441 cagcacagat ttagtgaact tgagagctta acaagaaaat tagagaaaga aggcggtacc
     4501 cgaggtccag cagggcctcc ggggccagcc ggacctaaag gggaacgtgg cgaaccaggg
     4561 cctgttggac ctatgggacc tagaggtgaa caaggtccta aaggcttaga cggagcacgt
     4621 gggcccgagg gacagcaagg aaaacctgga cctgtcggac ctcaagggcc ggcaggtcca
     4681 gcggggcaaa aaggggaaac cggacctcag ggacctcgtg gagataaggg cgatactgga
     4741 gaaactggaa agcaaggacc agcaggagaa cgtgggccag ctggacctca gggaccgcgc
     4801 ggagacaagg gtgaaaacgg tgcacccggt gagcaaggcc ctattggtcc aaaaggtgag
     4861 actggaccta aaggtgacaa gggagaacgc ggcgaaaagg gcgaccaagg tcaacgtggt
     4921 gaaaagggcg accaaggtca acgtggtgaa aagggcgacc aaggtcaacg cggtgaaaaa
     4981 ggcgagcaag gccaacgtgg tgaaaagggc gagcaaggcc aacgtggtga aaagggcgag
     5041 caagggccac gcggtgaaaa aggcgagcaa gggccacgcg gtgaaaaagg cgaccaaggt
     5101 caacgtggtg aaaagggcga ccaaggtcaa cgcggtgaaa aaggcgagca aggccaacgt
     5161 ggtgaaaagg gcgagcaagg gccacgcggt gaaaaaggcg agcaagggcc acgcggtgaa
     5221 aaaggcgagc aaggtcaacg cggcgaaaaa ggcgaccaag gtcagcgcgg tgaaaaaggc
     5281 gaccaaggtc aacgtggcga aaaaggcgac caaggtcaac gcggtgaaaa aggcgaccaa
     5341 ggtcaacgtg gcgaaaaagg cgagcaaggt caacgcggtg aaaatggtga gcaacagcca
     5401 aagggtgacc aaggaaagga taccaagcca tcagttccaa aggcaccaga atcaccaaaa
     5461 atgccagaga agccacaggc tcctgaaaag gctcctgcac cgaaagctcc aaaggcttca
     5521 gagcagtcag ctagccctaa ggcaccagca cctcagtcaa caccaagcaa aaaagcagtc
     5581 ctaccagcta caggagaggc aagccatcca ttctttagtc tggcagctct tagcgtcatc
     5641 gctagcgcag gtctgctaac cctaaaaaga aagaaaagct aagccagcta tttgacaata
     5701 gcttctagca actcgggata gatctgcaag gctgagcagt agcactatta aatctgaaac
     5761 aaaaacgcat gacgtcctcc ctaaaaaggg ttgaacatca tgcgtttttt tgtctaataa
     5821 tgccgaaagc aagcctagat aaggcctgct ccagcttaat cacttatgat aaggatttgt
     5881 acaattcagt agcatgctct actgtaaagc catattcttc aaagatacga ttgcccggtg
     5941 cagaagctcc ccatgtatca atggtcagtg ttttccctgc aaggccaacg tattttgccc
     6001 agccaaagct tgagcctgct tcaatagcta gacgttttgt cactgctgct ggtaggattt
     6061 cctccttgta ggaagctggc tgctcatcaa agatattttg tgatggcatt gataccacac
     6121 gcacatggat accatctgct gcaagagcgg cttgagtatc cattgctagc ttgacttcag
     6181 agccggttgc aatgataatc ccatcaaggt caccctttgc ctctgacagg atataagctc
     6241 ccttattaag gccatcttct gccaattcct tagtaccttc aagtacagga aggttttgac
     6301 gtgttaagac aagcattgtc ggacggtctg tctcagcgat cgcacgcttc caagcagcgt
     6361 ttgtttcatt gccgtcagct ggacgaataa cgttcagatt tggcattgat cgaacactag
     6421 ctagctgctc gattggctca tgggtcggac catcttcacc aaccgcgata gaatcatgcg
     6481 tcatgacata aaccgttggt agctgctgca aggctgccat acgaaccgct ggcaataggt
     6541 agtttgaaaa gacaaagaag gttccgccat aaacacgtgt tccaccatga agggcaatac
     6601 cgttcatcgc tgctgccatt gcaaattcgc gtacgccaaa ccagatgtta cgaccagcat
     6661 aatgacccgg ctggaagtct gtctcagcct taaccatggt attgttagag gcagaaaggt
     6721 cagctgagcc tccccagaag gctggcacct gctcagagat ttgttggata gcctgctggc
     6781 tagaaacacg actggctact gctgtgccaa gctcgtgagc ttgcaactca acctctgccg
     6841 cctcattagc aaaggctttt ttgtattcgg ctgctaactc agggtatgct gcttcataag
     6901 ctgcaaatag gtcattccat gcctgctcag cctgctcacc acgcgcctga aggccttgtc
     6961 taaagcgctc agtcacctct tgcggcacct caaaatcagc atgggtccat tgataagatt
     7021 tcttagcaaa ggcaatgcct tctgcaccaa gcggagcccc atgaacagct gaagttcctt
     7081 gcttttcagc accaaagcca atgattgtct ttacttcaat aatggttggc ttttcagtct
     7141 ctgccttagc ttcctcgata gctttagcaa tggcctctag gtcgttgccg tctttaacaa
     7201 ggatatgctg ccagccgtaa gcttcaaaac gccccttgac gtcttctgtg aaggccattg
     7261 aggttgggcc atcaagcgaa atatcgtttg aatcatatag caagacaagc ttaccaagct
     7321 tcaagtgacc tgccagactg gctgcctcct gactgacacc ctccataagg tctccgtcac
     7381 catttagagc ataggtatag tggtctacaa tatcaaagcc aggtctattg aacttagctg
     7441 ctaagtgtgc ctctgccata gccataccaa ctgcattggc aactccttgt cctaaaggcc
     7501 ctgtggttgc ctcaacgcca tctgtatgat tgacctctgg gtgacctggt gttttagagc
     7561 cccattgacg gaagttctta agatcctcaa tagacacatc atagcctgct aggtgcaaca
     7621 ggctgtaaag catggcacta ccatgacctg ctgataggat aaagcggtct ctatttgacc
     7681 aacggcggct tgtctttgga ttgactgtca taacatgatt ccatagcaca taagccatcg
     7741 gcgccgcccc catcggcaaa cctggatgcc cagaatttgc tgcttgaata gcgtccattg
     7801 atagagtacg aacagtatta actgccagct gatcaattgc atcaaatgtc ataagtaaaa
     7861 cctctctgtg tattacaact aaaaattaaa cgttttccat tgtctattgt aacataaaag
     7921 taaactgatt tttaacaaaa tcctataaag tccttaaatt cttatctagc aataagcatt
     7981 gctgttccta gctttttgtg attgacagct gtcttagata gagcacctat gctcataaga
     8041 aaaagcaagc ctagctgttg ccagctaagc aagcattcct ctttggtacc tccctttggc
     8101 tacagtaagc gccagctgcc tgttaattct agcgcaacag caaagcacca gctgatcctg
     8161 ccacctacaa atagctaatc ccaaactaac cgctacagcc acattagaat ataaggagag
     8221 ctctatgctc ttagcctatt ttttaaagga agcccaatcc tccataaagg tctttaagcc
     8281 atttgttgtc aatgggtgct cagtcatctt cgcaaataat ggatctggaa tggttgcaat
     8341 gtgtgcccct agctgtgcaa cagcttcaac atgggcagct gtccgaatgc tggctgcgat
     8401 gatttctgct tggaagccat acaaatcaat gatcccacgc aaatcactaa taagctgata
     8461 aggatctgct ccaatatcct ctaagcgacc aataaatgga ctgatatagg tcgcaccagc
     8521 cttcatggcc attagtccct gactaactgt aaaaataagc gtcacatttg ttttgatgcc
     8581 ttcttgtgac aagacattag ttgcttttaa gccctctgtc gtcatcggaa ttttcacgac
     8641 cacattgtca tgccacttgg caatgttcct agcctctgca atcatttcct ctgcggttag
     8701 tccggtgacc tctgcactga tagggccgtc cacaatctca cagatttcct tgataactgt
     8761 ctcaaaatca cgaccctcac gcgagataat gctagggttt gtggtaacac cgtccacaac
     8821 accaagctca ttaatcgcac gaattgcctc tacatttgct gtgtctaaga aaaatttcat
     8881 cttaacctcc gttaattagt ctgttatcag tcattgaaca gcatgacgct gtttaccgtc
     8941 tacattatca ttataaaagt cactcttagg atataaaaga ccaagtatca cacagtctag
     9001 tgttcaaaac tagacctagc tatgggactc tgtttcttta aaaggcttga ttcttacagc
     9061 tcctctgcaa aaaactgtgt ggctttgaca gctcttttcc agccttgata taacttttct
     9121 cggcgagact cactcatgct tgctttaaac agctgacctg tagcatttaa ttgctttagt
     9181 gtctccatgt ccttccagta gcctacagca agcccggcta aaaaggctgc tcctagagct
     9241 gtggtttcaa gattttcagc acgagcaata tcaatcccta aaatatctgc ctgaaactgc
     9301 atgagcatgt tattcatagc cgctccgcca tcaacacgta attgctggat agtgatccct
     9361 gagtccacct gcatggtatc aatcacatct ctgacctgat aagcaataga ctgtagggta
     9421 gccttaacaa aatcctcttt tgttgttcca cgcgttaagc caaatactga gccgcgtgca
     9481 ttggaatccc aataaggagc gccaagacct gtaaaggctg gtacaacata tacctcatca
     9541 gcattggttg aagccaaggc tagctgttca gactcaaaag aggtttttat cattcgcaag
     9601 ccatctcgta gccattgcac agcagagcca gcaataaaga tagacccttc taaggcataa
     9661 taaaccttgc cattaatacc atatccaatc gttgttagca ggttgctgct ggataattga
     9721 gcctcttgac cagtattcat gatgataaaa gagcctgtgc cataggtatt ttttaccata
     9781 ccaggctcaa aggccagttg cccaaatagg gctgcctgct gatcacctgc catgccagca
     9841 atagctacct ctcctccgta aaaatgaaaa gaagccgttt taccataaat ttccgaatta
     9901 gacctgacct caggaagcat ggccttaggg atattcagca aggccaatat ctcatcgtcc
     9961 cattttagct ctttgatatt gtatagcatg gtacgtgctg cattagaata atccgtcaca
    10021 tgtaccgccc cgtccgttag cttccaaacc agccaggtgt caatcgtgcc aaataataat
    10081 tctccccttt cagctcgctc ttgagccccc ggaacatgat caagaagcca tctgagcttg
    10141 gtcgcagaaa aataagcatc tataaccaag cctgtttttt catggatcat tttggtatag
    10201 ccatcacgct ttagctgctc tgcaatggag gctgtttgtc tagattgcca cacaatagca
    10261 ttatagatgg gcagacctgt ctgtttgtcc cagactaccg ttgtttcacg ctggttggta
    10321 atgcctatag cttctatttg ctctggcttt ataccagact cgataaaggc gtctgcaata
    10381 acagactgca ccaaattcca aatgtgattg gcgttgtgct caacccagcc agcctgtgga
    10441 aaaagctgtg gaaattcctt ttgactacta accagcgctt ctcctttctt attgaaaata
    10501 atggcacgag agctcgttgt gccctgatca atagccataa tataggtttc agttcccatg
    10561 tgtcctccat tctatcgctg ctgagatagg ctctctcaat catagcaagc gctttctact
    10621 ctattataca acatttacag cccatagcct atccttctag tcataaaagt atcactctgc
    10681 caaatcctaa gctgataatg cctatcattt caactaaaca gcccttatca cagccaaata
    10741 ccagcaacaa aggcgggcta taggctagcg cctaaatggc tgccaacaag ctccagctct
    10801 atcaggcaca acaaggaaca acaaaaaacc taagcccttt tagcatataa aggcttagga
    10861 atgttacagg cttttatcac ataagcggtg atagcttttt aatcgtaaac aggctcagag
    10921 gacttttcta aaatatctcc actattagca tcaatagtat agctgtactc ctgatccttg
    10981 gcgtcaaact caatatcgta gaccacccta ccgtcgtctg tttctttcgt cagctttagc
    11041 ctttgggcgt cagctgctgt gattgaggcg tccttaaaag caagctcctt ggccttgtcc
    11101 tctgaaatgc cagctgcttg atcagcctga ccaccagctg cttgagctga agcaggagcc
    11161 tcagtgattg gctcagagga tttttctagg atctcaccgg tattagcgtc aatggtatag
    11221 ctatactcct gatccttagc atcaaactca atatcataga ccactctacc atcgtctgtt
    11281 tctttcgtca gcttgagcct ttgagcgtca gctgctgtga ttgaggcgtc cttaaaggca
    11341 agttccttgg ccttgtcctc tgaaacactt gccttcctat gattctgagc actgccattt
    11401 tgacctagag cctgattctg ttgacgacaa gctgataggc tgattaagga tagactcgta
    11461 agagctatta ctgaaagttt tttgattatc attgtattga ccttccgtct ttattcatct
    11521 tatttcctct agtatacatt aaataatctg attttacaat tttaaagcgc taaaactctc
    11581 ttaaccaggc ttactccctt atatgataac ccccaaagag cccataaggt aaaggtaagg
    11641 actttgctat ccctcaacca agaatagatc acccagccga ataaaaaaag caattattgg
    11701 tagaatgaga agaattattt tggtcttatt tattgccttc accagctatc aatcactatt
    11761 taatgaccat tttggtatga accctcactg ccactcacta tctgacacca agctactttt
    11821 aagtaccagc atcgatgttt cttacacctc cagtgcgtat ccatagccga ccttcagcat
    11881 ttaccagcat ttctgattga ttacaaatac tccctaaact gttgaaaaag tatctaaacg
    11941 aaccatacaa aacttaattt accttttttc tatataaata gctaaaaaac atagtaaggt
    12001 cacaagggat ataagattta cattgcttat agtagtcgat aagaaataaa aaattaaaaa
    12061 aataaagtaa gaagcccctt ctttgcccct cttagcactg tcaaccagta tatagataaa
    12121 aattaaagca taaagacctg aaaaagtaat caataacatc taatttacct tatatgccaa
    12181 gcatgctcct aaagcagtaa agccgtctat acatactcct tttagcaccg gatgaggtat
    12241 tttgcaaaat gtaattcctg tcttgagacc tcctaatccc ccgataacag cattacctgc
    12301 tgcatttcct cctgaaatat cttgcatttc acttattgct aatgctctat aatgttccat
    12361 ttctattatc ctcctaaaac aaggttccaa actcagaatc tttctgtttt tctcatttct
    12421 aaaagcctcc tgtgacacca atagatccac aagctactcc acatactgga aatccaagtg
    12481 ctgcgcctgc acttcctgct ccaatcacac ctgacacatt ggcagcccaa ttattttttc
    12541 ctccttcaaa gctagcaagc atttctgtag ccattacgtc aaattattgt attgattgca
    12601 aatactccct aaaaatcgat gttgtccagt tgcaaccttg acatatttag tataacgctt
    12661 tttttgtaaa acattcctcc atatcctaaa cagtcgttga aacgtcctaa atgggagcat
    12721 ttttttcgtt taagactgca aagtgaccat taagggaagg cgtgaagcga caagcctgtg
    12781 gctttaggaa ccttaaaaac attaaaagca agcttctcat tgctattaac aacacaaaaa
    12841 aagcaccagt ctggtcctca ctaggtacta gttatcagtc acccccctaa agttgacaag
    12901 aagccaaaaa aagagaactg actagctctc ttagtgtgca gacaaatcta tctgcttaca
    12961 ttaatgacaa ttctcagaag tgcaaaagac agctattagc ccttacttga gtacctctcc
    13021 tttgcttggc ctactagaga ttctctcaat caggcgacta gtccggatta aaagccagtc
    13081 tagccaagcc catgaaattg ctgatagagc tcttggcgat tcaccttata gtctttggcg
    13141 attgtcttga tcgcctgatt aggcttcatg ccagcagcaa tagcctgttg aacaagtgct
    13201 agcagatcca aatcctcagc aggctctgat gcgtcagctt gattggcacc tgccacaatc
    13261 aatagacact cacccttgag tggatggtct gctagatagg tcaagacctc tgaaatctga
    13321 ccacgctggt attcctcaaa aagcttggtt aactctctca ccagcaccac ctggcgatcc
    13381 ccatagcagg ccagcaggtt tgttagcgta tccttaacac gataaggaga ttcataaaag
    13441 atttgagtct ctggataatc tgccttagtc atcaaaaatg ccctttgctg cccagctttt
    13501 cttggcaaaa agccataaaa cagatggggc tggggcgcca agccactagc aatgaggccg
    13561 gtaatgcccg cagaagcacc cggcaaagca acaacagtaa tatctcgatc aatagctgct
    13621 ctgactagct catgaccagg atctgaaata gagggcatac cagcatcgga gacctgagcc
    13681 aatgaccttc cagccaacaa caggtccagc aaatctggaa ttttatcata agcattatgc
    13741 tcatgaaagc ttacctgctt tgtctttatc ccaaaatgct tgagcaacag accagtattt
    13801 ctcgtatcct ctgcacagat aatatccacc tcttttagaa cattgaccgc tctaaaggtc
    13861 atatcctcta ggttaccaat aggggtaggc accagataga gaacccctga ctctttttct
    13921 tccttgaagc tcttttggat ttgcatgact ctactttcta tctaatagct ctcgacaaaa
    13981 catacactct tcatcatttt cacgacgttg cccatagaaa aaattgcaga tatgaaagcc
    14041 ctcatcataa atgccctcca agtggtcctt gccctgctta gaagaggtct tggccagatt
    14101 ttcgtgctcc aattgactca agcgctcacg taatttggtg ttttcaagcc taaggatagt
    14161 attttcctct acgagtcctt ggacctgctt tttcattgct tcaatttcag ctaaagtcac
    14221 catcaggttt tgtgaaaagc catcaaaagc gtcaaacagt tcttttttat tcactaactt
    14281 taacctcctc taaagcatag gttaccaagg ccagctggtc cttaaagcga acctgaatgg
    14341 tatctgtaaa aagatcaatt cctgcaacct cacctggtcc ctgcgctgtt cttactatag
    14401 taccataatc aggaaatttt ttcttacttt cttgataaaa atcgtcctca tattgtaggc
    14461 agcacagcaa gcgaccgcag cagcccaaag actttgccga atgcaaggac agcccttgat
    14521 gttttagcat tttgattgag actggaggaa actctcctaa aaagcttgaa cagcatagtg
    14581 ggcgaccaca gggacccagc cctccataaa cccttgcctc ctcacgacta ttaatctgac
    14641 gcagctcaat ccttgtcttg aaataggcag ccaaatcctt gaggagctgg cgaaaatcaa
    14701 cacgctcctg agcggtaaag gtaatcaaaa cataacgtct ctcaagggag aaaacaatgt
    14761 caaccaaggt catgtctaag ccatttctgt caatcatctc tgctactttt tgctttgact
    14821 gggctgctag ctgaaggttt tgctggtaag ccttgtagtc catgtcattg gcaggtctca
    14881 aaacagaggg catatccttt ggcaggtcgt ccttacaaaa gctttttatc ggagaattga
    14941 ccactgccaa tcgactgccc ttgccatcag atatgacaag cttggtttgc acaggaaagg
    15001 cctgatcggt ttgaacgtac ctgacagagc aggtgtcaca atatttaatt ccaatcgtac
    15061 ttatcatgaa atcaccatat attctaacgt attttgaaag ctgacattgc tttgccacat
    15121 aagtctagcc tgataaacag cctccagata ggtaaaagca ttttgtcgac tgtagtcctt
    15181 cgccaagatt aaggttaaaa gagttagtgc catgtcctgc tcctcttttt cctctgctag
    15241 ctgaaccaag cgattaagct ccagataagc ctgttcctta tcctgaaacc agatggaaac
    15301 aaaacgctca gcctgcgcca tcagctccaa cagcctggtg ttttcagaaa aagcggtaag
    15361 ctgctgggca ttggctgcta atctggctaa gaggtctgct tgatgtttca aaagcccctt
    15421 tttttgggcc agctcagaga ggtagtgctc atcttttgga aagtgaaaaa cctgtgtacg
    15481 gctcttgatc gttggtagga cctgattgtc atcattcgtt agtaaaaaca tatagcaatc
    15541 cccttgtggc tcttctatat attttaaaat gctgttagct gcattgacat gcatcttatc
    15601 acaatcctta atgataaaaa cctgccgcct gccctcatag ccggtctgcg aaaaatttgt
    15661 catcatttct ttgacggtat cagtcttgat aagctgaccg acaggctcta agatggtgac
    15721 atctgaaaag tcattgtgct caatcagctg gcaagcacga cagtgatgac aaggagcatt
    15781 gcctcttttt tgttcgcaaa aaagagtctt ggctaaaaaa agagccatgt caaaattggc
    15841 aaaatcacct gaaaagaggt aggcatgatt tagacgtttt ttttgcaaaa tctcttgaaa
    15901 ggcctgatag accctaggag ccttttgagc caaatccatt cctaacctcc tgctatgctt
    15961 gactgtgtgt gataatggca gctaaagccg ctgacacaac gctttctaag tcctgtgatg
    16021 catcaatctt gacaatacgc tggggatttt ccaaagccag ctccagatag cccttacgaa
    16081 cacgctggtg caaatctaat tgctcaagat caagacgatt gatctctcgc tcagtatttt
    16141 gtgcaatcct tgccaatcca agctctgagg gcacatcaaa atacagggtt aaatcagggt
    16201 caacaccatc tgttgcaaaa tgattgagcc attgaatggc ttgcttatcc agccctcttc
    16261 cggcgccttg ataagcaact gaactgtcaa taaaacgatc caccaaaacc aagtgtcctg
    16321 actcaagagc tggcatgatc ttttcaacca aatgctgcct tcttgctgca atatagagca
    16381 gcagctctgt tttatcgtcc atggtcgtgt gactgacatc taagatcagc tgacgaatct
    16441 tctcagcaat cgcaacgcct ccaggctctc tcgttgttac aatggtttgt cctagagctg
    16501 cctgtaagag tggcaccagt ctttccagca ccgttgtttt tcctgctccg tctggacctt
    16561 caaacgttat taattttcct ctagtcatct ttattccttt gtttatcgtt acctctattt
    16621 taccaaaatt tgcctgaaaa agcactgcca attcattggg cagtgccaga tcagaaaaaa
    16681 gcctttttgt gctgcctttt aggcgatagg aataaaaagc cagccctcaa agcagcagcc
    16741 taagacttgt gcctcacacc tcaaagccta tgagcagcca ctcgataaat gacaatcgtc
    16801 tcagctctta ttttctttgc ctaagcaagc cagcagggct gatccatcag ctttgagcaa
    16861 ttgatgagct aagacatgct atataagaca ggatcaggcc tacttagccc tgctcaggta
    16921 gggcttgagg ctctagaggc tcacgatgta aattcccaac aaaatcacaa tcaatgtcat
    16981 caaaggctga taccttcacc tctttgacaa atgttagccg actaatgtcc tttagctttt
    17041 cttccatgtc ctctttattg atgtaaataa caaggtatcg agaacgcctg gaatggtagt
    17101 acaagtcacc atatttcatc acttttctag cgtctcgatt gtaatacagg tagataacca
    17161 gcccaattct ctgctgtttt tgaaacattt aggtactctt ttcttttata ttttgatacg
    17221 gtccaagctc atgtcgaggt ctatttgtcg ccaagggaag tcctgtgtcg acaagaatat
    17281 cctcagacac tgcttctgca atagctgtcg aaatcgtcgc caaaacctcc tgcaaatcaa
    17341 cctgtgccaa gcgcagatca gcaaccaatg gatgcaggtc aagctggcgc ttttgatgaa
    17401 gtaattggca gcgcaacgct ctagcatctg gacacaactt aagcaagtcc tgcctaagct
    17461 cataatcctg cttaagctcc tcaaataagg ctaactcggt ctgtagggcc aaatctgcct
    17521 caaaagcctt tttagccaag gcataggcct gatactggct gcttgtccta atatcctgaa
    17581 ccagctgctc aatagccttt tcaatggcaa acaattcttc atttatgatt agcataggtt
    17641 aattatacca taattttaag gaagatagcc ctctttagca tgcaaaaagc ccctgaaaca
    17701 atttgtttca gaagctgtta agctatttta ctaagctctc taagctagct cattattttc
    17761 catgatttca tcaataaagc cataggctag ggtttcttct gcgctcatcc aataatcacg
    17821 ctcagcgtcc ttatggattt gtttgatcgt tttaccggca ttttgtgcca aaatcttttc
    17881 caggcggtga cgtgtcttta ataaatgctc agcagcaatg gccatatccg tctgctgcgt
    17941 accacctcct gtgcctccca taggctggtg aatcatatat tctgcatttg gaagcataaa
    18001 gcgcttgccc tttgcacctg atgaagcaat aacggttccc atagaagcag ccatacccat
    18061 aacaatggtt tgcacatctg ccttaataaa gttcatcgta tcaacaatag ctaaaccagc
    18121 tgatacagag cctcctgggg tattcacata gaggtaaata tcttttgtgt tgtcttgggc
    18181 atctaaaaac aagagctgcg caataacaga gtttgccata ttatcctcta ctggaccagt
    18241 cagcatgata atacggtcct ttaacagacg tgaataaatg tcataagaac gctctccacg
    18301 actggtttgt tcaataacta caggaatcat aaaaatctcc aatctatcgt gactgtctaa
    18361 caccactctg cctcatgcag tgacaggcag tcaaacacat ctttttataa tgattgacct
    18421 tattataatc tcttggtcaa aaaaggtcaa atgataaact tgcttttaaa aaccttccag
    18481 cctaaactag aaagtcttat tagctttagc aggctagcct ctagcaagca gagcctagca
    18541 caaccaaagc ctgtagcctt ttacttggta ccaaataagc gatcaccagc atctccaaga
    18601 ccaggaacaa tgtagccatg atcatttaat ctttcatcaa gggctgcggt ataaatgtca
    18661 acatctgggt gagcctcctg aagcttttta accccttctg gtgctgctac cagacacaca
    18721 aacttaatat tagcagcccc acgctttttc agtgaatcca ctgcaagaat agcagagccg
    18781 ccagtagcca gcatcggatc aacaataaaa atttggcgct gatcaatatc ctctggcagc
    18841 ttcaccaaat attcaaccgg ctccaaggtc tcctcgttac gatacatacc gatgtgacca
    18901 accttggcag ctggcacaag actaagaaag ccatccacca taccaatacc agctctaaga
    18961 atcggaacaa ttgctaattt tttacctgct aactgctttt gaaccgtctt ggcaaccggt
    19021 gtttgaatct caacatcctc taatggcaag tcacgagaaa cctcgtagcc cataagcatt
    19081 gcaatttcat tgaccagctc tctaaaatcc ttggttgagg tatcctgacg acgcaggatt
    19141 gatagcttat gctgaataag tggatgcgaa ataacctgac attttcccat gatgacgtac
    19201 ttccttcttt attttttaca cttttgctat tataccaaaa aattgaaaac cttgcttact
    19261 tttttcagat ccggttgaaa tgataaaagc aagaatctga tcagctagct gcctgcttca
    19321 gctgccttga tcttgggtgt caaagtccca atttttggcg atacctagct gctctgctgc
    19381 caattaattt gtccagctga cgcgtcaata acgtcatgta ggcgtaaaca cccattccca
    19441 agccaccaat aatcactaag taaagcaggc tagtcaatct gcctgtcggc ttaaacaaat
    19501 agcccaaaaa ccagttagct agtagcacaa tcaggcccat caatgctgtc tcaatcaccg
    19561 ttagtaatat acgcttatgc agcagcttac ggttaaatcg tgtgacctga tgtagacgac
    19621 ggtacatgag atagataggc actagcaagc caagggtcgt agctaacaaa ggaccataag
    19681 catgaaacag atagatcaaa ggaacctgca aaaccagctt gacaaaaaca ccataagcaa
    19741 aataatagat ggccttacgg ttttcaaaca gggcctgcag catcggagaa aaaagcgtat
    19801 acaaggccat caatagggta aggcaaagca cagcaacaaa cagcctaaca gcctgtccct
    19861 cgctactacc gtaaaaaacc gtataaagag gccttgccag tataatagct cctgtcagag
    19921 caggcaataa aaacatcagc agcatttcaa tgttgttaat gatcaggcgc cctgctgctc
    19981 gcatgtcctt tttaatgtaa ttttctgtca ataaggcaat accaacacta ccaattgaag
    20041 cggctactgc aatgagcacc atggtgattt tagcagggtt ggcgttaaaa tacccaaaca
    20101 gcacccagag ctgagaacgc gtgtagctgg taaacagagt catcgtattg acaaaggtcc
    20161 actgatcaag gagctgaaag gcctgaatcg cacttcctgt aataataaag ggaatcgact
    20221 cctttaacgt ttcaataagc aagcccttga tgtcaatagg aatcgcatgc tctgtcttgg
    20281 taaaaatagc ctttaaaagg ccctgcgtcc agaaataata aaagagcacc gccatactgg
    20341 ctatcattcc aataaaagca gcaaaggtgg actgcgtaac agctgcaata tagtccttag
    20401 accccatttt catgatgaaa aaggttgtta gaagcatcca gatcacacga accagctgct
    20461 cagcaatttg gctaagagca tagggcttaa tctccttata gccctgaaaa atccccctaa
    20521 tcacgctcat cactggaaaa acaaaaacag ctaatgataa gctatgcata atcgggacaa
    20581 gggtctcatc accaccggac aagcgagcaa agagcggaga tcccagatac atcagcactg
    20641 agaaaatcaa gcctaatacc agcataacct ttagagtgct tcgaatgagc tgatagctat
    20701 gctcttgctg tcccatcgag ttgtacttag cgacctgctt agcaatggca acatttagcc
    20761 ctgttgtcga aatcaacaaa aaataggcat acacattgta tcccatatta aagagcgcat
    20821 ttgcctgtat cgcatactgc cccatccata tgtaccatgg aataatatat agaacgccta
    20881 aaagtcggct aataaaatta cctgcggtgg accaggctgc tccctgaacc atcagctgtt
    20941 cttgtgtcaa ttgttttttt tctgtcgaca tatccgttct tcctagtttt tatagcttta
    21001 ttataaactt ttgcttgtga cttgtaaaac aagaacatta aggataaaat aaggctatga
    21061 taacaattga gcacttatta accattttaa aaaaggacca taatttccga gaggttcttg
    21121 atcaagacgg ctaccacttt aactatagcg gtctacagtt tgacagcctt agctacgaca
    21181 gcagacaagc agatgagcag acgctctttt ttgctaaggg atcagctttt aaggctgact
    21241 ttttgagaca ggccattgcc aagggactaa gactctatgt ttcagagatt gactatcagg
    21301 tagggatccc tgttattctt gttaacaata ttaagcacgc tatgagccta gctgcgatgg
    21361 ccttttatga ttacccacaa aataagctca agctattagc cttcaccgga acaaagggca
    21421 agacaactgc tgcctacttt gcctatcata tgctaaagga atctcataag cctgccctgc
    21481 tctctacaat gaacacgacc ttagatggcc aacacttttt taaatcgcag ttaaccacac
    21541 ctgaaagtct tgatttattt gcgatgatgg ctcagtgtgt ggctaatggc atgacgcatt
    21601 tggtgatgga ggtctctagt caagcctact tggtcgggcg tatctacggc ttaacctttg
    21661 atgtcggtgt ctttcttaat attagccccg atcacatcgg accaatcgag cacccaagct
    21721 ttgaggatta tttttaccat aagcggctct taatggaaaa tagccgagct gttgtggtca
    21781 atagcggtat ggagcatttt aatatcctag cagagcaggt ggctgataag cctcatgatt
    21841 tttatggcaa aggggcttgc aataggctgc tgcagcggca ggccttctca tttcaagcag
    21901 ccggcaaggt agctggagac tatgcgattc aattaattgg cagcttcaat caagaaaatg
    21961 ctatggctgc tggactagcc tgtcttcgac tgggggcaag cctagaggat atccgccaag
    22021 gcattgctaa gacaaacgtc cctggccgca tggaggtctt aaccatgacc aatcaggcca
    22081 aggtatttgt tgattatgca cataacggtg atagccttga aaagctccta tctgttgtcg
    22141 aagagtacca gaaaggccag atttacttga ttctaggagc accgggcaat aaaggcgaga
    22201 gccgtcgggc tgattttggg caagtcatca accagcaccc caatgttcgt attattctga
    22261 ctgctgatga tcctaatttt gaggacccac agctgatttc agaggagatt gctagctata
    22321 ttcaccgcga ggttgatatt atcattgacc gtaaagaagc aatcaagact ggtatggagc
    22381 gctgtcagaa tgagcaggat gcactcatta ttgctggcaa gggggctgat gcttatcaga
    22441 ttgtcaaggg acaaaagact gcctatgcag gtgatttagc gattgcaaag agctacctat
    22501 agactggtct aacaggctaa acagtaataa ttcttaagat tactgataat gattctaagc
    22561 tggctccttt tttagcataa actcagtaat tagattctga aaggcttttt taggcctttt
    22621 ttctatgcta taatgggata gcttttaaga gaaagcgcac tattatagtc agaccaaaaa
    22681 agcgactagc atttcatagg ctatcagccc cttagaattt tgctagctgg ctttgcttga
    22741 ctattagaaa ggagaaaaac catgtcaaca atcagtgctg agaggatttc agctggctat
    22801 gatcaatcgc ttatcatcag caacttatct gtcactattc ccgaaggaaa ggtaacaacc
    22861 atcatcggtg ctaatggctg tgggaagtca acccttttaa agactctggc acgactattg
    22921 ccactcaaag cagggcaggt tctcttagat ggacaagcca ttgctagact agcaaccaag
    22981 gacgttgcca gaacactagc agttttacct cagctgcaag aagctactac agctactgtc
    23041 tatgagctgg tttcttatgg gcgttatccc caccaatcct acctaggaca actcagtcaa
    23101 gctgataagg ataagatttg ctgggcaatg gaggtcacaa gcatggcacc ctatgctcat
    23161 caggctgttg atgccctgtc aggcggccaa cgtcaaaggg cctggattgc tatggcctta
    23221 gcacaggata ctgatattat ttttctagat gagccaacaa cctacttaga tatgaatcat
    23281 cagctcgata ttttagaatt actaaaggag ctcaatcagg tctctggaaa aacaatcgtg
    23341 atggtccttc atgatttaaa tctttcagca cgctactcgg atcatctgat cgccatgaaa
    23401 aatggacata tcaaatattc tggagaggtc aaccaggtga tgacgccaga gatgattcaa
    23461 gacatttttc aagtaaaggc tcagctcgtc actgatcctc tctatcattg ccctacattg
    23521 ctgacctatc agctgatata aatttattct aggagaatag aatacatgaa aaaactactg
    23581 cttattttaa ctgtttttgt gacagctttt acattagtcg cctgctcaag tcaaagcaag
    23641 caacaagaaa gcaccagcaa agcaagccta tcccacaagc caaaaattgc tggagtgacc
    23701 tattatggtg acattcctgt caagccaaag cgcgtggtta gcttagcagc tacatatact
    23761 ggttacttgg caaaattaga ccttcatctg gtcggtgtca cctcctacga caaaaagaac
    23821 cctgttttaa caaaaagcat tactcaagcc aagcaggtgg cagctactga cctagaggct
    23881 attacagcac tagagcctga tctcattgtt gttggctcaa cagaagaaaa cattgaccag
    23941 ctagcaaaaa tcgcaccact aatctccatt gaataccgca agcgtgatta tttgcaggtg
    24001 ttttctgatt ttggccgtat ttttaacaag gaaaaggaaa ctgaccaatg gttggccgac
    24061 tggaaacaaa aaacaagtga ctatgaaaaa gaaataaaac aagtcaccgg atcagctgct
    24121 acctttacaa tcatggggct ctatgaaaag gaaatttacc tttttggtaa ggactgggga
    24181 agaggtggtg aaattattca tcaggcctta cattatgatg ctcccgaaaa ggtgaaaaaa
    24241 gaggtgttta agcagggcta tctgtcctta tcacaggagg ttctaccaga ttatattggt
    24301 gattatgtga ttgttgctgc tgaggatgac caaaccggct cagccttata tgagagcgac
    24361 ctttggcagc agatccctgc tgtgaccaac aatcatgtca tcaaggtcaa cgctaatgtc
    24421 ttttacttca cagacccact gtcactggag caccagcttg aggttctaaa aaaggctatc
    24481 ctctcaactg gtgcaagtca ataaaaactt aagatgacag ctcaacatca tactaagcct
    24541 aaactagcta aagcagctcc tccttggctg atcttaacct ttatcagctt aactctagtg
    24601 cttgccattt actgcagtct gaggtttggg gctgtgtcac tatcacatca ggagctctat
    24661 catattctac ttggaaagca ggaccagggt caaaaggcca gcattatttt ggacattcgc
    24721 ctgccccgct tgattttagc agctctagtt ggtgctgcac ttgctgtttc aggagctatc
    24781 atgcaaggca ttaccagaaa tcccattgcc gagcctggct tactgggaat caactctgga
    24841 gctgggctgg cattagtcat cggctatgct ttttcccctc atcttcatta ttcgacaatt
    24901 atattacttt ccttgctagg gtcactctta gcgaccctat taattctcag cctagcctat
    24961 caagctggta agggctacac tcaaatgagg cttattttag caggagcgat gatatctatg
    25021 ctactgtcag ctatcggaca aggaataaca acttattgtc acctagccaa tgccattatt
    25081 ggctggcagg cgggaggatt gatcggggtc aattggcaga tggttagcta tgttgcgcca
    25141 ctcatcatct gtggcttagc cctatcttat ctgctagcct atcatttgac cattttaagc
    25201 ttaagtcaag agcaggccaa ggccctaggg caacgcacct tcttgattag ccttatcttt
    25261 attggacttg tgctgcttct gtcttctgct gctgtagcag tagccggcag catttccttt
    25321 gtcggcttga ttatccctca tgccatcaca ttagtcactg ctaaggatta ccgctggatc
    25381 ctgccgctag ctactcttct tggagccagc tttatgcttt gggtagactt tgcctgtcgg
    25441 aatatcaatc ccccctatga aacaccgcta tctgctttga tcagctttat tgggctgccc
    25501 tgctttttat ggctagttag aaaaggaggt cgcttttgac agctactaaa agacacgtcc
    25561 cattatttct aggactaatc tctggactgg tctgtttgat gattatttcc ttgtctattg
    25621 gggaatctag catgtcacca ttggaggtcg tcagggtgct ttttggtaaa tccactgctg
    25681 atatggcctt gatcatcacc aacattagac tcccaagaat tttagctgcc tgtatcggtg
    25741 gcggctcact ggccctttct ggcttaatgc tgcaaagctt aacgcgaaat catctggcag
    25801 attctggcat actaggcatt aatgctggtg ctggtatggc tattaccctt gtcatatcct
    25861 acagcactag taacagtctg accagcaggc aagggctgcc gcttatgacc atatccgggg
    25921 caatggcaac cattgtcttg gtctacctgc tctcacttcg tcatggccat attgatccta
    25981 ttcggctgat tgtcactggc gtagggctat caaccatgct atctagcctg atgattgcct
    26041 ttgtcggcaa tgtgaaccgt tataaggtgg attatgtgat tcattggcta agcgggcagc
    26101 taacaggcga tgattggtcc aagctaagca ttgttgctcc cttattgggg atcacttggc
    26161 tgctagcctt tagtcaagcc tataagctca acatcatggc attaaatgat gaagcaagca
    26221 tggctctagg cttcaagctc catcagtacc gtaccattgt tcttgcacta tctgcgattc
    26281 tctcagccct aagtgttatt ttggtcggaa acatcacctt tattggtctg atagcaggcc
    26341 ataccagcaa acgactagtg ggagctgatc accgattaag cctgcctgtc agccttttca
    26401 tcggcatgat tctgcttctc ttggctgaca ctatcggacg agtctatctc gtcggcagca
    26461 atataccaac cggtattctt gtctcaatta ttggtgcatc ctattttctc tatctgatgg
    26521 tcaaaatgac ataagagcct ctgctgcata gcttaaaggg ctcagcaagc ataaatggct
    26581 tagactcaac tgttttacag tgtgggtcta agccattttt tattcatcaa gtcaactctt
    26641 aatcagcgta gaaaatcagc tgctccttat caaaagccag cttcaggcag tatttagtgg
    26701 cctctacttt ttcaatatag cctagaagct ccaaggcatt cacaaaaata tctgtccgct
    26761 tttgcataac aatctctttt ctagcaaatt ttagaagaaa gctggtcatg tacttcaagg
    26821 catagtcctg attcacatca cctaataggg catagagcct taattgctca tcagataggg
    26881 cttcccctct tcttaagcgg taaaaataat tggcaagcgt cagcttatct cggtcaatgg
    26941 ttgttttttc cttgatcaaa acctgattgg tctgattaga cagcactgtc tcaaacacca
    27001 aggccatcaa agcttcatat agatctgatg ccctatccac aaagattaga tcttctaatg
    27061 tcacctgctg caggtcatct agcaagggca gacacagata gtagcgtctg ttttttcgac
    27121 agatatagcc agcctgaatg taagcttcaa gcgccttatc aatcccctta acatgagaaa
    27181 aggcctgctt aatgtgacgc agggttacgt catcatgctg attgaggtaa tgaataaggt
    27241 cttgaaaaaa aggctgacgc gttaatttat cagggttaaa aatggtaatc atactactat
    27301 tatagcaaaa agaccaaagg gctgctgata aaaatcaaca cccctctaca ggcaagctct
    27361 atgctccaaa gctttcagtt aattgaggga caacctgctt tttacgagat acagcacctg
    27421 ctaggaaagc atgattatcc tcaagcttaa agctaaaggc tgcctcaacc ttatccatat
    27481 tcgcaccaag cgccaaaatc tctgaatttg aattaacaat atctgtaatc atcaagacaa
    27541 aatcagaata gccctcactt gccatcacct ctctaatagc ggcctcaata gcctccttgc
    27601 gctctaacac ctctgcaatg tcaacggtat tgacctgggc tacacgaact gcgttgccat
    27661 ttaattcaaa ggtcttagca tcaatatcaa tcaattctgc ttctgattta cttgcaaggt
    27721 ttgttccggc ctttagcata gccataccgt attcctctag cttaactcct gctaactctg
    27781 ctaattccgc agcaacacga tgatctgaag catgcgttgt tggtgatttt aacagcaagg
    27841 tatcagaaat caagccagac aaaagcatgc ctgcaatgtc ctttggcaca tcaaccctat
    27901 tttccttgaa caggcggtaa acaatagatg aggcagagcc aacaggttcg acacgcatat
    27961 aaagcggatt tgctgtctca aaattagcca cccgatggtg gtcaacaata ccatacacct
    28021 caacctcacg aatatccgaa atagactgtg gaaattcgtt atggtctgtt agaataacat
    28081 gactagcacc ctctgctttt gctgatgtca ccactcttgg tgctgatacc ccaaaatagt
    28141 caagggcaaa ggctgtttct tcatttgggt cacccagagc gactacctcc gtatccaaat
    28201 caaaggcttt ttttgctaag tagtcaaaag catacgatga tgcgatggca tcagtatctg
    28261 gattttgatg accaaaaact aatagttttg acataaagtt tctacctcat tctctttatt
    28321 catcttattg tagcagaaat aggctctaaa atcaaagaag attccccagt cacaggccaa
    28381 gagtctaaag ggcataaggg cacagaatct caggtattaa agagtcctgt caaacacaca
    28441 agaacaggca agccagtcca aaaagcaatg ccttctataa tgagctattc agctatttgg
    28501 ggacaataca ctgtccttga ttggtttaat gcttcaagga ttactttttg gcacgtgtct
    28561 gagctcgctt aaaaacactg aaggtctcat caagccagcc gcttcatcag caaaaaaacg
    28621 gctctataat ttccatggtg gatttaccca ctacagaaat tatagagccc atttacctcg
    28681 ctttgcacat cacacaagag aaaacgagct tcgtctcgtg cttagttatc agtcacccac
    28741 tacagttgac atggggccaa aaaaagctgg gcatttccca actctagctt agcctatgat
    28801 tgatgaatac ggttcatgta ttcagtatag gattctgtat gcagcagctt tttggcattc
    28861 tccacccgct ccttggttgg tggcttaacg ccctcaagct ggtatggaat ccctaactcg
    28921 cgccatttga actctcccat cgtatgataa gggagtacct caaacttgtc gacatttctc
    28981 aaggtcttga caaacgcatc taagcgtacc aagtgatcat caatgtctgt caagccaggc
    29041 accaagacat ggcgaatcca gacgggcacc tgcctatcag agaggtagcg agcaaactgc
    29101 aggatatttt tattgggctg acgggtgaca agcttatgct gctcctcgtc aatctccttt
    29161 aagtccagca aaatcaaatc agtaactgct aataatgttt ctaacagctc atggtattca
    29221 ggggttggac gataggcaaa gccacaggta tctagcgttg tatggatacc tagctttttg
    29281 gcctcagtaa agagcgcagt gataaagtcc atttgcagca tagcctcacc acctgacaca
    29341 gtgattccac cctttttccc ccaaaagtgc ctatattgca gagcctcctt taggacatca
    29401 ttaacggttc ggcgttgaga ttgattggtt tccatagccc aggtgtccgg attatggcaa
    29461 tactggcaac gcatcttgca gccctgcaaa aaaatgataa aacgtatccc cggaccatca
    29521 acagaaccaa agctttctgt agaatgcacc attccagtta cttgcccata atctacttca
    29581 accattgtgt ctccttcacc cttgtaaatg gttttacgtt ttcattatat catgtttcat
    29641 caaaaagact aagctcaatg cctagtcttc agtaatattc tgttctatat tagaaatagt
    29701 aagtttcaat ttggtgatac gaccgtcctt tactttgtca ttgaccaaaa ccagatgctt
    29761 ttgcttgcta tcacaggcaa agctctcttt ctccttttga cttggaatgg taccaatccc
    29821 tgtcaaataa aagcccgcga tggtatcgac atcatcactt tctaattctg tgtcaaaata
    29881 ctcgttaaag tcgttgagcg tcattgtccc tgtgacaata taggtgttgt catcaatgtg
    29941 atgaacaaat tgctcagcct tgtctgtctc atcatcaatc tcaccaacga tttcctcaag
    30001 caaatcctca agcgtcacca aacctgcaac ccctccgtac tcatcaagta ggatagccat
    30061 ctggttttga gtatttcgca attgcctcaa caaatcatct acaaaaatcg tttctggtac
    30121 aaagagcggc tcctgcagaa gctttctcat gctgatgttt tcaaagccct gacgaaagcc
    30181 tgattctaaa agccttttgg tatgaattaa gccgatcacc ttgtccttgt caacatcata
    30241 aactggaata cgagagaagc tctgctttag gatttccttg atattgtcta gcgtatcatc
    30301 gttaatgtca atcatgaagg catctgtcct tggaaccatc acctcacgcg ccatcatctc
    30361 atcaagcgag aaaatcccct gcagcatttc aatctcttcg gcatcaagcg ttgcctcgct
    30421 gttagtcagc atgtactcaa tctcatcacg cgtcatgcgc tcatctgcgt catcaaaggt
    30481 cattggggta atccggctca gtaaatttgt cgacgccgat aagagccaaa caaagggact
    30541 aaccaatttc cccaagataa tgatcactgg ggcagaaatc acagcaagct tgtcttttag
    30601 attcatagct atccgcttgg ggtataactc tcccaaaaca atcgagacat aggtcaagaa
    30661 caccaaagaa ataatgctac cagctgtttg agcggtcgca gaaccaccta accagccaga
    30721 aataacctgc cctaaagagg ctgacaggct cgcccctgac aagaggctaa taaaggtaat
    30781 accaacctga atggtcgata aaaagttatt gggctgctct aaaacacgca gcaagcgatc
    30841 atacctctta tccccatcgg cagccttttg ctccacacga gagcgattta aggataccag
    30901 agccatctca ctggctgaga aaaaggcatt taacaaggtt agaatgacta acaataaaaa
    30961 ctgaatcaat aaaggctgac tcacagggtc ttccattaat ataactccta aaacataata
    31021 tactacttca ttatatcaca attgtcgcca aagattgctg atttatttct ttttcctgag
    31081 aaatcacaga cagtctaagc cctgacataa ggctggctga agcttaatca gtagctgcta
    31141 ttttttccag catgattaaa aatggcggct gattcatctg attgatcggc tgatagagca
    31201 ttgctgttac ctggcgctga ttgagctgac caatatagtc caaaagctct tccttctccc
    31261 tactaccgcc atcatgacca taatacacca tgatagcaat ccgtccacct agctcaagcc
    31321 gatcaagtat tttagctagg gctaatatgg tcgtctcagg ccttgtgatc aacgacttat
    31381 ctgcattggg tagatagccc agattaaaaa tggctgcccg aatgggctcc ttaacatatt
    31441 gatccacctg ctcgtgtcca gctaaaataa gctctgcatt agtcaagcct tgctgctcca
    31501 agcgctcttg tgtcttggtc agtgcctgct gctgcacatc aaaagcataa accctttgtg
    31561 acagacttgc taaaaaggca gtgtcatagc catttcccat agtagcatca acagcaatac
    31621 tctgcttatc caaaacttct tttaaaaatt catgtgatac atgaatagga cgctttatca
    31681 tcttatcctc ctaagcaaat acttcaaatg ccgcgatacc atctagtatg tctaagtcaa
    31741 tatgccttcg gccgtaacaa tctagcacat aatctttata ccgatctgtt tttagattga
    31801 attgaagcga ccagatcagc caaaaaagat caatatgtcg atcgcttttt cctgcctccc
    31861 cccaatcaat catggactga aattgccacc gatccaagat catatttggc aaacaaaaat
    31921 ccccatgaat cagagtttca tgctgtaaca agagcttaag ctcctgaatc cgcctgtaag
    31981 cctcctcctg ggactgaaac cgttgctgag gcggtaaaaa gcactgattg aaccgccctt
    32041 ggtgataacc agcctcagca gcttcgatat aggctagcgt tttgtcagct acaggaaaat
    32101 cagacaaaga caggctatgc agctttagca tatgatcaac taagatacga cataagcgct
    32161 tgggatcgga caaatattca atatgactgg cgtcctctcc tgctaccttt gcggttaaaa
    32221 gccaatcctg atcaccgctg atataatcaa gcacctctgt tgctaagccc ttactatgac
    32281 aataccgagt tagggcggcc tccttggcaa gcctaccttt agcggctgtt tttagaaaat
    32341 agccctgccc tttatcaata gcataaacac gtgcctctgc cgagctactg ctatcataaa
    32401 ccaaactgtt ttgtaacagt ttttttaaaa caggtggtag gctcagctcc tctcctgcta
    32461 tcaatctttg tttcattgct tcccccgatt atcccttaag cttacagccc tgccagctat
    32521 ttcttctttc catttctagg tcaatcgcat tcaaaacctc ccatttattc aggctccaca
    32581 tgggaccaat cagcatgtcc ctaggcgcat cacctgtgat gcgatgaata atgatatgct
    32641 caggtatgat ttctagctga tcacagataa tcgatacata gtccttctga ctcaagagct
    32701 gcaagcgtcc ctcatgatag tctctttgca tacgcgtatt ggtcatcagg tgcagcaaat
    32761 gcagcttaat gccttgaata tcattgtctg tgacacagcg tctaacgttt tcgatcatca
    32821 tctcatgggt ttcaccaggc aagccattaa tcaagtgaga cacaatgtta atgttagggt
    32881 actgcctcag acgctgaacc gtttccttat acaagtcata agaatgcgcc cgattaatca
    32941 gctgggaggt ggcttcataa gttgtttgca gcccaagctc cactgtcaca tgcatgcgct
    33001 ctgatagctc agccaaataa gcaatcgtct catctggcaa acaatcaggc cttgttccga
    33061 tattgatacc aacaacgcca ggctcattga ttgcttgctc atagcgctcg cgaataacct
    33121 ctagcttatc atgcgtattg gtaaaatttt gaaaataaac caaatactga ttgacctcag
    33181 gccacttgcg atgcataaaa tcaatttctt tgtaaaattg ttccctgata ggtgcatcag
    33241 gcgccacaat cgcatcacct gagccagaaa cggtacaaaa ggtgcagcca ccatgagcaa
    33301 ctgtcccatc acgattagga cagtcaaagc cagcatcaat gggcaccttg aaaattttag
    33361 caccaaataa acgacgataa tactcattta aggtctgata tctttttgtc atgcctctat
    33421 tgtagcacaa atcccccgat taacagcaga agatctcaat tggctgctac ttctctgatt
    33481 gatgagccaa agcaaggcaa ctaaaaagga ttgaagaaga cctctggaag agacctgcct
    33541 tcaatcacta gcttttctag aactgatctg taacgcgcca tacagctgac tgatcactgg
    33601 atttactttt gctttagctg aaaacgccat tcaaagcgct tttgatcata aaaaggataa
    33661 agcagctgaa gtatgccaaa gcctaaggca tagccagcca acacatcgct aggataatgc
    33721 actcccagat aaatgcgtga caagcctatc agcaaaatca aggccaaaag ggctatatca
    33781 accagccagc gtaaggaggc tgactgcaat ctttgatggc aaataatcag cagacttcca
    33841 ataatcaaaa ggcttcccat cgaatggcca ctcggaaaag aatagccaga agcatgcacc
    33901 aaatgctcaa tgctgggtct tggtctttga tacaagagct ttagcaccca aatcaaaagg
    33961 gccgcaaaaa caccatttga taggacaaat aaggcctcag ctctccagct caaggccaat
    34021 aaagccagca cagcaacaac aacaatcact gcctgtgtac taacatttcc agctacagtg
    34081 atccctttaa aaaactgggt tagcccttca ggcagatgac ctcttagggc taaccgaagc
    34141 tgactatcaa aagacgttag gtcttcggga aaaaatttaa caatatagcc aagcaccaca
    34201 aatagtagca tagcaaagga agacaatagc agatgttgtt gtttatgttt catgatatga
    34261 attcggatat ctctctaaaa ttggtttacc tgcaatatac acgaaataaa agacaattgc
    34321 aaatattagc ccctccaaaa ggttgaaagg aatgaccatt gtaaatatgt agcgagcagt
    34381 accaataaaa gctttaatat caaagccagc aaacttggca tataagggaa tagcaaagac
    34441 atagttcatg acaaccatac caagcgttaa cagccctgtc cccacaagac tagctagtac
    34501 ataggtgacc agccctttct gacgatgcca aatcaaggca aaggcagtga taaaaagcgc
    34561 aactgctata acattcatcg gtataccaat caaatcatta acgccatgat tgtttaaggc
    34621 tagtctaagc aaggtcctca ccgctaaaat caagttagct tgctttagat ccatcaagac
    34681 caagcctaac aaaatcggaa tgatactaaa atcaatcttt aaaaagctgg ctcctggaat
    34741 aatggaaaac cccacaaaca tcaggcaaaa ggatatggct gaaagaatgg caaccatcac
    34801 cagttgatgt gtttttgaca taaaaaattc ctccaatttt gacaaattga aagaagctcc
    34861 ttcgtatgag caggcaaaaa gtcaactcaa aaacccggtc ttctctcttc cagactttac
    34921 tgtcggttgt ggaatcacac cacatcagct tgcgctcgcg gacttctagc tgcactagtc
    34981 accgccggtc gggaattaca ccctgccctg aagacactta tagcatagca aatttaaacc
    35041 tatagcgcaa gacatttttt tgaagcctag cttttccaac aaacacaaga catcaggcaa
    35101 aaaagctaga tgaaagcaac agcaagaaaa atcactttga ggctacaaag ctctctacga
    35161 ggtaggccac cctgtgacat ggcactagcc tagctcaagg caaaaaagag cagactagaa
    35221 gaaacctcca ataacctgct ctggtattac taccgttgtc ccctttacgg tcatagacac
    35281 acctaaccaa tgaaaactcc aatcagagtt ttcagattga agaaaaagtc cattttagac
    35341 ggttttcttc aatctttttc ttttaatcaa aaaaacaaaa gaagtctgaa aaatactgta
    35401 atatcagcat ttcccagagt tttcatgata tgatagtcaa tttctaaatg ttcaattttt
    35461 ctatcgctga tagggtttgc ctacattctg aactccaatc ggagtttttt ctttttggct
    35521 ttagaaaacc tttggcacag ctaatggctc caaactggtg atggtgattc atcagccctc
    35581 tagggcagcg cctttgcttc ttactgctgc tcacaccgca agctctagca gtgtagtgac
    35641 tgtagctggt aggacagtaa gtccttcttg tctcacatca ggctgctata gcccctgttc
    35701 tgtgtcttga tcgc
//
LOCUS       DARYVE010000017        35453 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYVE010000017 DARYVE010000000
VERSION     DARYVE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35453
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            49..222
                     /locus_tag="TVW25_000756"
     CDS             49..222
                     /locus_tag="TVW25_000756"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378409.1"
                     /translation="MKGFLAISKAWSFNRRISYWFFWIYEKELLFFDVAGIKYGKIGS
                     IKSLSTFRLAEIC"
     gene            467..1420
                     /locus_tag="TVW25_000757"
     CDS             467..1420
                     /locus_tag="TVW25_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1378410.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            1420..2166
                     /locus_tag="TVW25_000758"
     CDS             1420..2166
                     /locus_tag="TVW25_000758"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1378411.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            2415..3419
                     /locus_tag="TVW25_000759"
     CDS             2415..3419
                     /locus_tag="TVW25_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1378412.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            3716..5902
                     /locus_tag="TVW25_000760"
     CDS             3716..5902
                     /locus_tag="TVW25_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1378413.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            5980..6801
                     /locus_tag="TVW25_000761"
     CDS             5980..6801
                     /locus_tag="TVW25_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1378414.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVPLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(7097..7555)
                     /gene="nrdI"
                     /locus_tag="TVW25_000762"
     CDS             complement(7097..7555)
                     /gene="nrdI"
                     /locus_tag="TVW25_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1378415.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFPVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(7951..9135)
                     /gene="sezV"
                     /locus_tag="TVW25_000763"
     CDS             complement(7951..9135)
                     /gene="sezV"
                     /locus_tag="TVW25_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1378416.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            9385..10608
                     /locus_tag="TVW25_000764"
     CDS             9385..10608
                     /locus_tag="TVW25_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1378417.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEKAAKMTKELADK
                     LSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKTAEAEKLMENVG
                     SLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTELEKAKTELAVS
                     ERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVAELEKEVEAAKA
                     EVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEMLEKKDHANADL
                     QAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESANPFFTIAALTVI
                     AGAGMAVVSPKRKEN"
     gene            10831..13050
                     /locus_tag="TVW25_000765"
     CDS             10831..13050
                     /locus_tag="TVW25_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1378418.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            13065..13508
                     /locus_tag="TVW25_000766"
     CDS             13065..13508
                     /locus_tag="TVW25_000766"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1378419.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(13635..14927)
                     /locus_tag="TVW25_000767"
     CDS             complement(13635..14927)
                     /locus_tag="TVW25_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1378420.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            15682..16530
                     /locus_tag="TVW25_000768"
     CDS             15682..16530
                     /locus_tag="TVW25_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1378421.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            16680..17813
                     /gene="ugpC"
                     /locus_tag="TVW25_000769"
     CDS             16680..17813
                     /gene="ugpC"
                     /locus_tag="TVW25_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1378422.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            17997..19616
                     /locus_tag="TVW25_000770"
     CDS             17997..19616
                     /locus_tag="TVW25_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1378423.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            19725..20087
                     /gene="traF"
                     /locus_tag="TVW25_000771"
                     /pseudo
     CDS             19725..20087
                     /gene="traF"
                     /locus_tag="TVW25_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            20201..20560
                     /gene="yajC"
                     /locus_tag="TVW25_000772"
     CDS             20201..20560
                     /gene="yajC"
                     /locus_tag="TVW25_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1378424.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            20734..21483
                     /locus_tag="TVW25_000773"
     CDS             20734..21483
                     /locus_tag="TVW25_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1378425.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            21493..22287
                     /locus_tag="TVW25_000774"
     CDS             21493..22287
                     /locus_tag="TVW25_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1378426.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            22319..23584
                     /gene="rseP"
                     /locus_tag="TVW25_000775"
     CDS             22319..23584
                     /gene="rseP"
                     /locus_tag="TVW25_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1378427.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            23854..25710
                     /locus_tag="TVW25_000776"
     CDS             23854..25710
                     /locus_tag="TVW25_000776"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1378428.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            25762..26319
                     /locus_tag="TVW25_000777"
     CDS             25762..26319
                     /locus_tag="TVW25_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1378429.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            26654..31051
                     /locus_tag="TVW25_000778"
     CDS             26654..31051
                     /locus_tag="TVW25_000778"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1378430.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            31173..31601
                     /locus_tag="TVW25_000779"
     CDS             31173..31601
                     /locus_tag="TVW25_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1378431.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            31731..32276
                     /locus_tag="TVW25_000780"
     CDS             31731..32276
                     /locus_tag="TVW25_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1378432.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(32455..33069)
                     /locus_tag="TVW25_000781"
     CDS             complement(32455..33069)
                     /locus_tag="TVW25_000781"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1378433.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            33434..34861
                     /locus_tag="TVW25_000782"
     CDS             33434..34861
                     /locus_tag="TVW25_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1378434.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            35127..35396
                     /gene="rpsO"
                     /locus_tag="TVW25_000783"
     CDS             35127..35396
                     /gene="rpsO"
                     /locus_tag="TVW25_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1378435.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT        10147 a         6998 c         8463 g         9845 t
ORIGIN      
        1 taaatttttt aatgaaatta atctaatgac ctaagagctg tctggaagat gaaaggcttt
       61 ttagctattt caaaggcttg gagcttcaac aggcgaatca gctattggtt tttctggatt
      121 tacgagaaag agctgctctt ttttgatgta gctggtataa aatatggtaa aatagggtct
      181 atcaagagcc tatctacctt tagattggct gagatttgtt aggcaatgcg tccctgataa
      241 aggttgggct tatgggacaa taggccttgg tgctgtgttt gtccttagta tgaaacctct
      301 gagacggcag agcaggatcc ggttggttta ggaccgcatt agcttatctt acgataaaaa
      361 agaagcttga aaggaaaggc tgctttgatc tgatagaggg tcactggttt tagggtttag
      421 gctaggggca agtgaccact gatgatatgg cagcaagggt atcgttatga aggcatggca
      481 agagctgaca attacagtcc atcgtgaggc agaagaagct gtttccaatc tgctgattga
      541 ggctggcagc caaggagtcg ctatcaatga cactgcagac tatatcggtc aagaggaccg
      601 ttttggggag ctttatccag ctgttgagca gtcagaaatg gttactatta cagcctatta
      661 tccaagctca gctgatattg atgacatcag acagaccatt aatcagggct tgaacaggct
      721 aaagcagtgt gatgtggagc ttggtgagtt aaccctgacc aatcaagaat tggctgaaga
      781 ggattgggcg gacaactgga aagcctatta tgagcctgct cgtatcacgc atgatttgac
      841 gatagtcccc agttggacag attatgaagc cacagcaggt gagaagatca ttaggcttga
      901 tccgggtatg gcatttggaa caggcacaca cccaacaact aagctaagcc tgtttgcctt
      961 ggagcaggtg cttcgtggtg gtgagacagt tattgatgtg gggacaggct caggtgtgct
     1021 atcgattgct agctctctgc ttggcgccaa agaggtcttt gcttatgatt tagatgatgt
     1081 ggcggtgcgt gttgccaaag acaacattgc cctcaatcaa gccactgaca atatccatgt
     1141 agcagctgga gacctgctaa aaggccttac tcaagaggca gacgttattg tcgccaatat
     1201 cttggcggat attttggtgc atgtgacagc agatgcttac cgtcttatca agtctgaggg
     1261 gtatctgatc atgtcaggga ttatttcaga aaagctggat atggtgaagc aggctgctct
     1321 taatgcaggc ttcttgctag agactcacat gcttcagggc gagtggaatg ctcttatttt
     1381 caaaaaaaca gatgatttat caggagtgat tggtggctga tgcagcagta ttttattaaa
     1441 ggcagggcag aaaaaatcgt tcagctgacc gataaggata ccattaagca tatgtttcaa
     1501 gtgatgcgct tgacggataa ggaagagctg gtgctagtct ttgatgacgg cattaaacgc
     1561 ttggcaaggg tgtcagacag ctcagcctat gaggtggagc ttatcaaaga gctggaagaa
     1621 aaccttgaaa tgcctgttga ggtgactatt gcctcaggct ttcccaaggg tgataagcta
     1681 gatgttatca ctcaaaaggc gactgagtta ggggcagcag ctatttgggg ctttccagca
     1741 gactggtcgg tggtcaagtg ggatagcaag aagctagcta aaaagcaaga aaaattagct
     1801 aaaattgctc ttggagcagc agagcaatcc aagcgtaatc gcgtaccgga gattcaacta
     1861 tttgaccaaa agggtgagct attaaagcag cttaagcagt ttgataagtg ctttatcgct
     1921 tatgaggaag cagctaaggc aggtgaaagg tcgacattgg cgcgtgagct agcaggtctt
     1981 agcccaggtc aaaaagtcct ctttatcttt ggaccagagg gtggtatttc ttcaaaagag
     2041 ctggctagct ttaagcaagc aggtgctatt actgtgggac tggggcctcg tatcatgcgg
     2101 acagaaacag caccgctcta tgccttgagt gctgttagct atgctctgga gctaatgtct
     2161 agctgatagt gctaatagga gacagcacct tgtggctcag tgcttgacag aaaaaagagg
     2221 agcatctgcg attatgctaa taaagcaccg cttaacaaaa agatcgctaa gaaggagact
     2281 gccgcaaatc aaagggctag tctagcccgc gtaggtgcag agctgtcggg cctttgcagc
     2341 ttcatttgta aaaaatataa caaatcatct caaaataaag atactcgtca aacggattgg
     2401 tagaggaggg acatgtggtt acgataaaag atgtggcaag gctagcagga gtttcgcctt
     2461 caacagcttc gcgtgccatc aatgacagtg acatgattag tcaggcgaca aaggagcgtg
     2521 tcaaaaaagc catggaggcc ttggattatt cgcctaatta ttcggcgcaa aaccttgtta
     2581 agcgaaagtc caatactgtc gggatcattt tgccggtgcg tgagggtcag gattcactgg
     2641 gaaataaccc ttttttcatg cagattattc aaggaattgc tgctgtttgt accgatcagg
     2701 gctacatggt agcccttgcg actggacgta gtgaggccga attgctaaaa aacgtgcaaa
     2761 acatgatccg tagtggcaat attggcaagc tgatttttct ttattccaaa acagatgatc
     2821 aggtttttga ctttgtcaaa aggcaaagag tggattgtgt tgtcgttggg caatcaacga
     2881 caaaggatcc tggcaatgct aaatttgtca acaacaataa ccatcaagcc ggctatgatg
     2941 cagcagcatt tctccttcaa aaaggctatg aggctattgt ctatgcttat actgacatgg
     3001 ccgaattggt gcaggcagag cgttataagg gctatgcaga gctgatgact tcaaaggctc
     3061 tggcagctca agccctttgt gtcacgctaa aggacgatag gaaaagtcaa aagcagctgt
     3121 tagaccaatt agccaagcgc tctaaagttg cctttgtagt ctgtgatgat gtgctagcta
     3181 ttcatttgca gcgtctcatc aagcaagtag cagctgacac ccagctagca atcgttagct
     3241 tcaataattc tgtcctagcg gagcttgcga gtcctgcctt gacctccatt gctatttttc
     3301 cctatcagct gggagagcaa gctgctgagc tggtcttatc aagcgcagcg ccatcaccac
     3361 agccagtctt agttcctcat cagatcattg aaagagagtc tacgcctttt attgtttgat
     3421 ttaccgttaa gcctattcct aagcaaagta ctgatagctt gcttaggaat aaggcttttt
     3481 atttaggaat ttattttgtt tgctaatagt attaaagaga agcaacgttt actttagcat
     3541 tttcattgaa atcttcttaa gaaaacgctt tacaaaacaa aaaaaggttg gtaaaataag
     3601 cttatcaaaa gcgcaaacgt ttgcgttgaa tgtgcttgtt tttaaaaagg aattgagagt
     3661 tcatcagctt ttagctggtt attcttgatt cctagtccaa aaaaggagag gtcgaatgaa
     3721 aacatcattc aaacaatttt ttagcttcga gttttggcaa aaattcggga aatgcttgat
     3781 ggttgtcatt gctgttatgc ctgctgcagg tttaatggtg agtattggaa attctctgcc
     3841 catgcttaat caggagtcgc agcttttagc gacgcttggt aatgtcattg ctcaggttgg
     3901 ttgggcagtt attggtaacc ttcatttgct ttttgccctt gctattggtg gcagctgggc
     3961 taaggagcgt gctggcggtg cctttgcttc agggcttgct tttgttttga ttaaccgtat
     4021 tacaggggct atctatggcg tttcttcagc catgctgact gatccagagg ccaagattaa
     4081 aagtcttttg ggcactgaga tgattgtcaa ggactacttt acaagcgtct tagagtcacc
     4141 tgctctaaat accggtgtct ttgttgggat tatcgctggc tttgtgggtg caacagccta
     4201 taacaaatac tacaattacc gtaagctgcc tgatgtgctg gctttcttta atgggaaacg
     4261 ctttgttcct tttgtagtta tccttcgttc agctcttgtg gccctagtat tagccttgat
     4321 ttggccagtt attcagtctg gtattaatgg ctttggcatg tggattgcct catctcagga
     4381 cacagctcca atccttgcgc cattcttata tggaacattg gagcgtctct tgctgccatt
     4441 tggccttcac cacatgctaa cgattccgat gaactataca gctcttgggg gcacctatga
     4501 ggtcatgaca ggagcagctg ctggaactaa ggtatttggt caagaccctc tttggctagc
     4561 ctgggttact gaccttgtta atctcaaggg ctctaatgcg tcaacctatc agcatttgat
     4621 ggagactgtt gttccggctc gttttaaggt tgggcaaatg attggtgcaa caggaacgct
     4681 tatgggggtt gccctagcaa tgtaccgtaa tgttgatgcg gacaaaaagc ataaatacaa
     4741 aatgatgttt atctcagcag cggcagcggt atttttgaca ggggtcactg agccactgga
     4801 atacatgttt atgtttgctg cgatgccatt atatcttgtc tatgcccttg ttcaaggagc
     4861 ttcctttgca atggctgatt tggtcaacct tcgtgtgcat tcctttggta atatcgagct
     4921 attgacccga acgcctatgg cgattaaggc tgggcttggt atggatttga ttaattttgt
     4981 ctgggtgtct attctgtttg ctgtgatcat gtatgtcatt gctgacttta tgattaaaaa
     5041 aatgaagcta gcaacagcag gtcgcctagg gaattacgat gctgatatac tagaaaacga
     5101 tgatacaaag cctttgtcac agcagtctat tgatggtcag tcacaggtcg tccaaatcat
     5161 taatctcctg ggtggacgtg agaatattgc tgatgtagat gcttgtatga ctcgcttgcg
     5221 tgtaacagtc aatgacccaa gcaaggttgg cagtgaggag cattggaagc aggcgggtgc
     5281 tatggggcta atcatcaagg gcagtggtat tcaggctgtc tatgggccaa aggctgatat
     5341 tttaaaatca gatatccaag acctgctaga ctctggtgca gtcattccag agccgaagcc
     5401 tgctcagcct gctgcctcat catcacagca gacggacttt aaaaacctaa cagaggctgt
     5461 tttggcagta gcagatggag aagtcttgcc aatcacagca gtttctgatc aggtctttgc
     5521 agctaaaatg atgggagatg gctttgctgt tgagccggca aatggcgcta tctatgcgcc
     5581 ggtaacaggt ctggtaaccc atgtctttcc aaccaaacat gcctttggct tgctgacaga
     5641 tagcggccta gaggtgctgg ttcacgttgg tcttgatacc gttgacttga atggtgagcc
     5701 cttcactgtc aaggttagtg agggtcagcg cgtatcggca ggagatctct tggctgaggc
     5761 tgacctaact gcgattacag cagcaggacg caagacaacg gttgttgtcg cctttaccaa
     5821 tactacaagc atcaaagctg ttaaccttgt tgcgactggt caacaaaaag cgaagaccct
     5881 cgttgcacag gtagagcttt aagaataacc aaagagagtg gtagatagca gtatgtcaga
     5941 cctgcaggct gccacttctc ttgtcgtata ggagaagata tgaccaagct cttaaccctt
     6001 aacacacatt cttggatgga agccaatgcc ttaaaaaagc tgttcgactt ggcagagcat
     6061 attttggctc agaactatga cgtgatttgc ctacaagaaa tcaatcagct gattgacagc
     6121 gaagcagcag tgccattatc aggctaccag ccaattgcag ggacacctgc cattcatcag
     6181 gataactttg ccctcttgct tgtcaattac ttaaaaaaac gtggccaaag ctactactgg
     6241 tcgtgggcct acaatcatat tggctatgat atttaccatg agggtgttgc gatcttatcc
     6301 aagcagccga tccaagcctc agacatttta gtctcagcgg tggctgacga gtatgattac
     6361 cacaccagac gggctttact ggccaaaaca accattgatg gcagggaggc agcagttgtg
     6421 agcctgcatt tgtcttggtt tgatcagggc tttgtcggag aatggcagcg attagaggca
     6481 gccctgcagc agctagcctg tcctgtgcta ttgctgggag attttaacaa tccaagtggc
     6541 caagagggct atgagatgat tctaaaaagc cccttagacc ttcaggatag tcatcaggct
     6601 gcagactacg tctttggaga ccatagtatt gttgctgcta ttgatggctg ggaggataac
     6661 aaagaggcct ttaaggtcga ccatgtcttt accagtaagg tctttaccat taacagctca
     6721 aaggtgacct ttgatggtgg tgaagcaccg gttgtcagcg accattatgg cctagaggtt
     6781 gacctcagct ggaagctgta acaaaaaaag ccagcaggac ttgatagact gctgacactg
     6841 taagaaacag atggttatct tagctcttag aagtaagctt atcgcaaggc ttctaagagc
     6901 ttttttgcat ttatatttca tgagcatatg agaaagttgc agacaaatgc tggacacata
     6961 atcagactgt gggctagtta catcgtctgc tctgatttgt gtcagatagt gatgatctgt
     7021 gctgccttgt gattggccag atatttacct catatcaata gcagaaagtc aagtctccct
     7081 cagcctatct cctagcttac gattgctgat catcagtcag tctagctaca attacctgtg
     7141 ccaagcgctc aatatcagca ctggtcccgc gtagttcgaa atctcccagc attggaaagc
     7201 caaagcgctt agcatactgc ttggctgtta gacaatactg gtgattgaag tttttgttgc
     7261 cagagccgat aatccctaaa caacgcttgg cattatcatg cgccgcgata aagtctccca
     7321 gcggattggt caagatttca acctcccctg agtcaatccc gtttcctcct tcaagatagg
     7381 tcggcaaaat agcaacaaag ctctccttga ctggaaaggt ttcgtgatga agctccttga
     7441 tattgattgc tttagtctgt atgtggtgct tttctgccag gtattgcgac aagcgcctaa
     7501 caaagctcag ggtattgccg ctaagactga taaaaacaag ggtcaagtct gtcataaaag
     7561 actcctttag caagattagt ttcctaacca gcttagcaca atacccctga atacacaact
     7621 catatgacaa tgctctgcac gacaaacgcg cgaaacagtc atttccgaat gatagtatag
     7681 acttaagcag atacattcac cgttttttct atagtaaaag ctatagaaaa taagatatct
     7741 tcttgaaata gctaaacatt gacatacaga aagctttgtt ttcttgctaa aaccctatca
     7801 tgcgtctgcc gtgcaatgct ctgacagcta gcccactagt cacatcacat aaaaaaggct
     7861 tggtgacaag gacggtaagt ccaaatcatc aagtcttttt atggagagag cttagtgtta
     7921 gctgttaccc gaatcaagag gcccttgctg ctaatgcttg cgattttgat aggtctttgg
     7981 gctttctccg gtatgctttt tgaaaaattt agaaaaatgt gagggatcag tgaagcccaa
     8041 cacgtctgaa atgtgattaa tggcataagc agagcgcagc aatgtcttag cctcttcaat
     8101 tttcatgttt gaggtgtatt ggtagatggt caagcctgta tcacgcttaa agatctgtct
     8161 cagcttggac tcgctcatgt taaaatgctg tgccagctca gcggttgtga cactcttatg
     8221 caggttgaca ctgatatatt ggataatggc attaaccgta ggagagacat gtttccagcg
     8281 gttgtcccgc agctcactca ccttttgggt gtaaaagacc agtgaggcat cacgaatttt
     8341 gagcacatct ggcattgagg ttgccagctc gctgtctctc atgaactcct ctcgtgaatg
     8401 gtaggcatca gcaatatcca taccagattg aatggcaatc tgggctagtc gatcaaaggc
     8461 aatgatagaa taattttttt cagagcgcag cgtatcacca ctcaccacag ggataaaggt
     8521 atttcgtaga ctgaagatga tttccttgag cttgtgcaca tcaccctctt gaacaatgct
     8581 agataaattt ttctcataat tgtagagaca aaccttagat tcctgcttct tgacaaacat
     8641 attggccttt tgcacctcga tattgtcgga aaaatcccta atatagtgac gtaaaggagg
     8701 tgataacaaa tcctctatct tgccggaaaa gaagtaatgg accacaatca agaggtcacg
     8761 aatagcattc aaaggataaa caggtaaatg ctttagcgct tggtaaagaa tctcttcttc
     8821 ttccttagtc aaatccttat cagcaacggc caccttaaaa aaggtcttat ccaaaacatt
     8881 acagcgccaa gggccaatta aaatataatg atcctgataa cggtatatta aaaaaagctc
     8941 attatagctt ccctgaaaga aaagattggt tgcctgttcc ttgtccattt gcctaagcac
     9001 tgcttgaaaa cgataataaa attcaaaggt atcatcattc caaaagcttt ctgtcacctg
     9061 atggtcctta tcaaatactg taattgataa cttcaaacag ccctgtagag attttactaa
     9121 cgacatagta tccatgctaa gcgtcacccc cttcataatc ctcacggtat cttattctat
     9181 cttaaaattt aagaaaagca aggatatgca cttataatga aaaaatagac ataaaaaaca
     9241 ataatataca ttcttgctta ttaaataaaa atgacaatgt actgcataaa gaagttcctg
     9301 tcattaaaat aaaagtgcca tgaggttata atagtatggt aaaacaaaaa agtgtgccca
     9361 taacgggtag agaggaattg acatatgttt ttgagaaata acaagcaaaa atttagcatc
     9421 agaaaactaa gtgccggtgc agcatcagta ttagttgcaa caagtgtgtt gggagggaca
     9481 actgtaaaag cgaactctga ggttagtcgt acggcgactc caagattatc gcgtgattta
     9541 aaaaatagat taaaagatga gcgtcaagct cttaccgaat cattcaacaa aactttatca
     9601 agatcaacaa aagagtataa taaactaaaa acagaacttg caaaagaaaa agaaaaagca
     9661 gctaagatga ctaaggaatt agcagataag ctaagcaatg ctgaagcaag tcgtgataaa
     9721 gcctttgcag tatcaaaaga tttagcagat aaactaagta gtgctgaagc aagtcgtgat
     9781 aaagcttttg cagtatcaaa agatttagca gataaattgg cagctaaaac agcagaagct
     9841 gaaaagttaa tggaaaacgt tggtagtcta gaccgcttgg tagagtctgc aaaacgtgaa
     9901 atggctcaaa aattagcaga aattgatcaa ttaactgctg ataaggctaa ggctgatgca
     9961 gagcttgcag ctgcaaatga caccattgca tcacttcaaa cagagctaga aaaagctaag
    10021 acagagcttg ctgtttcaga gcgtttgatt gaatcaggca aacgtgaaat tgctgagcta
    10081 caaaaacaaa aagatgcttc tgataaggct ttagtagaat cacaagctaa tgtagcagag
    10141 cttgaaaaac aaaaagcagc atcagatgct aaggtagcag agcttgaaaa agaagttgaa
    10201 gctgctaaag ctgaggttgc agatcttaaa gcacaattag ctaagaaaga agaagagctt
    10261 gaagccgtta agaaggaaaa agaagcgctt gaagctaaga ttgaagagct caaaaaagct
    10321 catgctgagg aactttcaaa acttaaagaa atgcttgaga agaaagacca tgcaaatgca
    10381 gatcttcaag cagaaatcaa tcgcttgaag caagagctag ctgacaggat taagtcattg
    10441 tcacaaggtg gtcgtgcttc acaaacaaac ccaggcacta caactgctaa agcaggtcaa
    10501 ttgccatcta ctggtgagtc tgctaaccca ttcttcacta ttgcagctct tactgtcatc
    10561 gctggtgctg gtatggctgt ggtgtctcct aaacgcaaag aaaactaagc tatttcctct
    10621 ttccccaatg gacaatagcc gaaataatag agcgactatc gttctaacac aaaagcaaca
    10681 gtctcctgtc tgttgctttt tgtgatatta gggctcatca gtctaggcta atggttttct
    10741 gcgctttatc tgcagctttg aggattcctt cttttgcttt tacagtgaaa gtgttaaaat
    10801 aggaaaaaca actagtaatt gaggaagtaa atggttaaag aaatcaattt atcaggagag
    10861 gaagtagttg cccttgctgc caagtacatg acagacggtg acgtcgagct tgtgcaaaag
    10921 gcgcttgatt atgcgacagc tgctcatttt taccaggtta gaaagtcggg ggagccttat
    10981 attgtgcacc ctattcaggt agcagcaatc ctagcagacc tgcatttgga cgctgtgaca
    11041 gttgtctgtg gctttttgca tgatgtggta gaggatactg atattactct agaggacatt
    11101 gagtttgact ttggtaagga cgttcgtgac attgttgatg gggtcacaaa gcttggtaag
    11161 gtagaataca agtctcacga ggagcagctg gctgaaaacc accgcaaaat gctcatggcc
    11221 atgtcaaagg acattcgtgt gattttggtc aagctagccg accgactgca caatatgcgc
    11281 accctcaagc acctccgtaa ggacaagcag gagcggattt ctcgtgaaac catggaaatc
    11341 tatgccccgc tagcccatcg cttggggatc agtcggatca agtgggagct ggaggatcta
    11401 gcttttcgct acctcaatga gatcgaattc tacaaaatct ctcatatgat gagagaaaag
    11461 cggcgggagc gcgaagcttt ggttgatgat attgtcacta agattaaagc ctacaccacc
    11521 gatcaagggc tttatggtga tgtctatggc cgtcctaagc acatctactc ggtttaccgg
    11581 aaaatgcgtg acaagaaaaa gcgctttgat cagatatttg acttgattgc gatccgttgt
    11641 gtcatggaga cacaaagtga tgtttacgcg atggtcggct atattcatga gctctggcgt
    11701 cccatgcctg gccgcttcaa ggactacatt gcagcgccta agaccaatgg ctatcagtcg
    11761 attcacacga ctgtttacgg gccaaaagga ccgattgaaa ttcagattcg gaccaaggaa
    11821 atgcatcagg tcgctgagta tggggtagca gcccactggg cctacaaaaa aggtattcgt
    11881 ggcaaggtca atcaagtcga gcaaaaggtt ggtatgaatt ggattaagga gcttgtcgag
    11941 cttcaggctg cctcaaatgg cgatgctaag ggctttgttg actcggtgaa ggaggacatc
    12001 ttttcagagc gtatctatgt gttcacaccg acaggagcag tgcaggaatt gcccaaggat
    12061 tcaggcccta tagactttgc ctatgccgtt cacactcagg ttggtgaaaa ggcgacagga
    12121 gccaaggtca atggccgcat ggtgcccttg acagccaagt taaaaaccgg tgatgtggtg
    12181 gaaattgtca ccaatccgaa ttcctttggt cctagtcgtg actggattaa gctcgtcaag
    12241 accaataagg ctcgtaacaa gattcgccaa ttctttaaaa atcaggacaa ggagctgtct
    12301 atcaataaag gacgtgagct tctggttagt tattttcaag agcagggcta tgttgccaac
    12361 aagtaccttg agcgtaagcg tattgaggag attttaccaa aggtcagtgt taaaagcgag
    12421 gagtctctct atgccgctgt tggctttggc gatattagcc cagtcagtgt ctttaataaa
    12481 ttaaccgaaa gagaaaggcg tgaggaggag cgtgccaagg ctaaggctga agctgaggag
    12541 ctggttaagg gcggtgaggt caagcatgaa aacaaagaga ttctcaaggt ccgcagtgaa
    12601 aatggcgtga ttatccaagg ggcgtctggg cttctcatgc gtatcgccaa atgctgcaat
    12661 cccgtaccag gagatgtgat tgaaggctat attaccaagg gacgaggcat tgctattcac
    12721 cgcgcagact gtaataacat caagagtcag gacggctatc aggagcgtct cattgaggtt
    12781 gagtgggatt tggagcattc tagcaaggat taccaagctg agattgatat ttatggttta
    12841 aatcgtatcg gcctgctcaa tgatgtcctg caaatcctat ctaacgccac caagagcatt
    12901 tcaactgtca atgcccagcc gaccaaggac atgaagtttg ccaatattca tgtgagcttt
    12961 ggcattccta atctggctca gctgacagct gttgttgaaa aggtcaaggc ggttccagat
    13021 gtttacagcg tcaaacgaac caacggataa aaaggagacc aaccatgaaa attgtgattc
    13081 agcgcgtcaa ggaagcctca gtgtcgattg atgggaaaat agctggcgct attgatcaag
    13141 ggctgctgct gcttgttggc ataggtccag atgatcaggc agaggatata gactatgcag
    13201 tgcgtaaaat cagtcatatg cggatttttt cagaccccga gggcaagatg aaccgatcca
    13261 ttcaggacat tgagggcagt gtcttgtcta tctcgcagtt tacgctatat gctgacacca
    13321 aaaagggcaa ccgacctgcc ttcaccgggg ctgctaagcc tgacagggcc agccagcttt
    13381 ataacagctt caacgctcag ctagagcagc ttgtaccggt tcagcgaggg gtctttggtg
    13441 cggacatgca ggttagtctg atcaatgatg gcccagttac gattatccta gatacgaagt
    13501 atcgataact gcctagcgat cgatcgtttg cttaggagag tcatataaag gaaaaacaaa
    13561 aagacgagtg gtatgagaag cactcgtctt tgtcgtttat gctgctgtgt tgaagctagc
    13621 tagggctact agtcttattt ttgcaggtct ttgtagactg cgatgaattc tgtctcagaa
    13681 attggggtta agctgccagt gaattggtaa gaagtaccat ttttagcttg gaaagtatta
    13741 ggtaaacctt taaggtattt gtcgatagtc tcagtggtaa ttgcttcgtg tgttttaaag
    13801 gtgtattcgt taatcagctg ctgctgtttg tcctgttggt aaatagtaac tgaacgatag
    13861 gttgtgctat agtcatcgtt aatatcctta gaaataaaat aggtttctac aacagaatct
    13921 gaatgtgtcg catagctaat gggattgttg acgtcatact ttgaattata tacttgagct
    13981 atcctgttag aatctatgat atagttaaag tcctcatcgc gatcagcatg gtagaccatg
    14041 cgttcactag ctccactgta aatctcaccg ttatggcttt gatgagttat atcaggatcc
    14101 tgcgtgactg ttgtactgat tcgcttgacg agctgatacc cgtctttgaa agcctgagtg
    14161 gtttcaaaag cctttttagc agcttcaaag agctcctcag aagagaccct gctgccatag
    14221 tatcttaacc cggtaagtcc ttctttacca aggctgtcag ttacatcaac attaacaagc
    14281 tgcccattgt cttttttgag gaatttaacg tgctgtgtca cagctacggc atctgaatct
    14341 tggattgggt ttcctgcctt atctgttacc ttaatgtcct tgagagctac cttgctaact
    14401 ttttccacaa ggacctgacc cgtcaagatg tatgtttggt ctttttgatg atactgtcct
    14461 ttgattggtg tcgtaaaatg gtctgtgcta agtatttcag ctgtagaagc ttttgttaat
    14521 ttggcatttt tcaaactaat gaccttaaag ctttctgctg aaggatctat gacgtcttga
    14581 actagcttta tcatctcatt tgtggtgtag gttttgccat attctagtct aatatcctga
    14641 taatgtggag atacgatggt gtgattagtg ttatctactc cagtgatatt gaccatgagg
    14701 tacagtcctg tggtttcttg atagtctttt gaatggattg gcttagtggt gtcctcgtat
    14761 ttatagtgat ttgctaccct actagagctt gaccatgccc acccaacttt gtaatggttt
    14821 gctttaacgg caggtgctcc caaggtcatg gtgaatagtc caatgactac agttcctatt
    14881 tctaaaggtg ttttcccaag gtgatacagt ctttttgaag tcaacatatt tcaaacctcc
    14941 ctaaatcctg tcagtctcta tagttataaa aatacagaga atcgttagaa gaattaatgt
    15001 ttcatgccgg caagatgagt gtaacaaaag attggtgccg atacaagaag atggagatta
    15061 gagcatctgg tttcaatgag agttacataa tagcagaagg ttttttcact atgagagcta
    15121 atcgtcttaa aatggtataa tagcaagtga ataggctatc taactggttt aacagccatt
    15181 tttagagaag cttaatagta ttgctgataa gtgactcgta tctccatatt gcttttcaaa
    15241 ggctatgtta gctatgataa gcgtgaccag gctatcggaa aatccagtgt tcttaaaggc
    15301 tttgaagctc tggctttgaa ccttagctct ggtgtttcta tgaaaatgac ttgggccttg
    15361 taccagataa gaatgaagtc aaattgaggt tttttgacaa aatgtttgag taaatacaag
    15421 ttcatagaag tctaatgtat aaaaatacaa ttgtatcgcc ataatctgaa tgaccaaacc
    15481 attaaaaaaa taaaattttt aaacattttg gaaaacgctt tcaaaactaa aaagaactgt
    15541 cctatagtca ttgcttagca ttaaagcaag gtgtgaaatg ttatcatatg gagaaatagg
    15601 ctgtcttgtg ctgtatctgt gccaaaaaag aatgcttgtt tttgtgatat aatgtgacta
    15661 agaaacctga aaggaatgct tatggcatta aaagactatt ttcctgatat gcaagagggt
    15721 gcatttcctc tggctgacca agattggatt agcgttgagg ttggggagca gtacctccat
    15781 ttccccaaat ccagcttgtc agagcgagag cagcttttgc ttggtttggg gcggcagcgc
    15841 aaagagccgt ccaaggatca gaaatctcct tggtatcatt atttgattct gggccaaggg
    15901 gagcagccgg aggagtttca gggttgccag ttcatctata tcaaccatca atgtccttta
    15961 gcaggtgatt tgattgagct tctaaagggg atcatagagg gagttgaggc tgttttgccc
    16021 attagccaga ccaggacagc ttttttggtc tgtcaccata gccgttcaga cctttttcag
    16081 ctcttagcaa atttattgcc cacgattgag agcgattttg gtttggcctt gatgattttt
    16141 atcggtaatg gctggtatca ggtgtcagga aatgccttga gagactattt taaggaagaa
    16201 aatgctgtgt ttacagctta tcttgctgag cactctgcca gtcgcttgct gaccttttca
    16261 gaggtcatgc tctggtcact cttagcaaac agtggtttgc cagccttgtc aaagcatttt
    16321 agtcagctgc ttttagccaa taaagaggtc atggatctgg tgctcgccat gtggcaggag
    16381 catggcaacc tggtacagac agcccagcgc ttgtatattc atcgcaattc gctgcaatat
    16441 aagctggata agtttgctca gcagtcaggt ctctatttaa agcagctaga tgacttggcc
    16501 tttgcttatc tatttatact gaagcattag atttgtgcag ggtgcccaaa gacatttggg
    16561 cgttttgtct atatgatgaa aacgctatct ttgctataat aaaagcatca aataaaaagt
    16621 gtcagggttg ctagcattgc agtcagctag cagcctatct gacccattag gagtaacgca
    16681 tggttgaatt aaacttaaag cacatctata agaaataccc aaataccaca cactatgctg
    16741 ttgaggattt cgatttagac attaaggata aggaatttat cgtttttgta gggccttcag
    16801 gctgtggtaa gtcaacaacg cttcgtatga ttgctgggct tgaggatatt tcagagggtg
    16861 aattgaaaat tgacggtgag gttgtgaatg acaaatcacc aaaggaccgc gatatcgcga
    16921 tggttttcca aaactatgcc ctttacccgc atatgaccgt ttatgacaac atggcctttg
    16981 gtctcaagct acgtaaatac aaaaaagatg atattgatcg tcgtgtcaag gaagcagcag
    17041 aaatccttgg cttgacagaa tttttagaac gtaagccagc agacctttct ggtggtcagc
    17101 gtcagcgtgt ggctatggga cgtgctatcg tgcgtgatgc caaggtattc ttgatggacg
    17161 agcctttgtc aaacctagac gctaagctgc gggtgtcaat gcgtgctgaa attgcgaaaa
    17221 ttcaccgccg tatcggctca acaacaatct acgtaacgca cgaccagacc gaagcgatga
    17281 ccttggcaga tcgtatcgtt atcatgagtg ccactaaaaa ccctcaaggc aacggtacaa
    17341 tcggaaagat tgagcaggtt ggctcaccac aggagctcta taacctaccg gccaataaat
    17401 ttgttgcagg ctttattgga agccctgcga tgaacttctt tgaggtggtt gtcaaggacg
    17461 gtcagatcat cagtgaggac gggcttgata ttgctattcc agaaggtcag gctaaaatgc
    17521 ttgaagcagc tggctataag ggcaagaagg ttatttttgg tatccgtcca gaagatattt
    17581 caagcaacca aatcgtgcat gacacctatc caaatgccaa tgtcacagca gaggtcttgg
    17641 tttctgagct gcttggatct gaaaccatgc tttatgttaa gcttggtcaa acagagtttg
    17701 cttcacgagt tgatgcgcgt gacttccaca atccaggtga aaaggttagc ttgaccttca
    17761 atgttgctaa ggggcatttc tttgatctag aaacagagca agctattcgc taataacacc
    17821 tcctagaata aaatcctcat cttgcttgag gattttttaa caaaagaaaa tgcaagcgat
    17881 tgcgctatca aaaagaaaaa gggatttatc ataaagacaa cagatgttct gtagtgctag
    17941 gcgatcataa tgatggcacg aaatagcagg agactgttta gtaataagga gatatgatgg
    18001 aaaaacactg gtggcataaa gcgacaattt atcaaattta cccaaggtcc ttcatggata
    18061 caagtgggaa tggtattggt gatttaaaag gaatcacagg taagctggat tatctacagg
    18121 agctagggat cacagctatt tggctgtctc cagtttatca atcaccaatg gacgataacg
    18181 gctatgatat ttcagactat caggccattg cagctatttt tggtgatatg gctgatatgg
    18241 acgagctgct tgatgaggcc aagcagcggg ggatcaaaat catcatggat ttggttgtca
    18301 atcacacctc tgatgagcac gcttggtttg tggaggcaag agaaaatcct gacagtccta
    18361 aacgagatta ttacatttgg cgtgatcagc ctaataatct catgtcgatc ttttctggct
    18421 ctgcttggga atatgatgat gcctctgggc agtattatct gcacatattc agtaaaaaac
    18481 agcccgactt gaattgggaa aatgctgaat tgcgtcaaag catttatgac atgatgaatt
    18541 tctggattga taaggggata ggtggctttc gcatggacgt cattgacctg attggtaaga
    18601 ttccggattc tgaaattaca ggcaatggcc caaggctgca tgaatacctc aaggagatga
    18661 accaggcaag ctttgggaat catgacctga tgactgttgg tgaaacatgg ggcgctacac
    18721 cggaaattgc tcgtcagtat tcacgtcctg aaaataagga gctgtcaatg gtctttcaat
    18781 ttgaacatat cggcttgcag cataagccaa atgcttctaa atgggattac gcagctgagt
    18841 tgaatgttcc ggctctcaag gagattttta gcaagtggca gacagagcta aagctaggtg
    18901 aaggctggaa ctcccttttt tggaacaatc atgacttgcc tcgtgtcgtc tccatttggg
    18961 gaaatgatac agtatataga gagaagtctg ccaaggcaat ggctattttg ctgcatttaa
    19021 tgcgtgggac accttatatt tatcagggtg aagagattgg catgaccaat tacccctttg
    19081 agcgcttgag tgatgtgaat gatattgaat cactgaatta tgccaaggag gctatggcta
    19141 atggcatgtc agaggaggct gttcttgatt gtatttgtag ggtgggtcga gacaatgcaa
    19201 gaacaccaat gcaatggagc agtcaaaaga acgccggctt ttcaactgct gatcagacct
    19261 ggctgcctgt caacccaaat catcaagaga ttaatgtggc tagtgctcta gctgatcctg
    19321 attctgtttt ttacacctat caaaagctta ttcagctgcg tcagacacag gattggctgg
    19381 tggaggcaga ttatcagctg ctggaaacat cagataaggt ttttgcctat aagcgtcagc
    19441 ttggtagaga gacttacctt gttgttgtca atctgtctaa tcaagagcag ttttttgaag
    19501 aaagtcttca taaggcccaa gtgattatca gcaataccga tgtgcaggca gtcgtagaaa
    19561 gtcaacagct ggagccttgg gacgcctttt gtgttaagct tgatgagacc ttgtagccta
    19621 gctgcttgct gtgcctcagc tcaataatcg tagcgattct ttgagaattt tgacaaattg
    19681 ctgtatgatt agtagaagaa ttagatacaa aagaggaggc tgagatgacc gttgaagaaa
    19741 ccatgacctt tgcaaaaagc attgcagcat ttagataggt agagattagt gaggtagtca
    19801 ctaggctagc agcaggtgag gacatcaccg tctttttagg cagagcgacc tgtccttatt
    19861 gtcgtcgctt tgcacccaag ctagcaagcg tagcaaggca ggagcataag gatattttct
    19921 ttgtagatag tgaagactca acagagcttg cagacctgca ggcctttcgt gagcgctatg
    19981 ggcttgctac tgtgcctgcc ctgctcatta gtcgtcatca ggaggtcaag gcagtctgtg
    20041 attctagctt gactgaggaa gccattttgg ctttcctaga gcagtgacag acagctaatt
    20101 atctggtgca agtaatagaa atgtaatcag tcatgtcttg ctatgtgagt ccaaatctgc
    20161 tatagtagga catgactttt agacgaaata aggagatatt atgggcttac caacaatttt
    20221 aatgtttgtt gtcatgattg gtttaatttg gtttatgcag cgtcagcaaa aaaagcaggc
    20281 gcaggagcgc caaaatcagc ttaatgcgat tgaaaaaggc gatgagattg tgacgattgg
    20341 tggcatgttt gcagtggtcg atgaggttga tttagcagca aagcgaattg tcttagatgt
    20401 tgatggtgtc tatctgccat ttgagctatc agcgatcaag cgcgtggtcg aaaaaggaag
    20461 tgcagtgaca tcagctgatg tggatacgac agagactgca gttgatgaca cagcggttga
    20521 ggcttcagac gaagctgaat cagctattga gacaaattaa gaaaatgagg tctgaagcat
    20581 tagtgtttca gactttttta ggtgatgata gcaggtagcc agacagagct gtcatgtgct
    20641 atggaaatat cgtctacaac gagaaaaagc gagccaaacc gcatgaaata tggtaaaata
    20701 tgaggtaagt atgcttgtga ataaggaaaa aacatgtttg gattaaaagc gaagtcaaaa
    20761 aaaatcgttt tggataggat tccaaagcac attgggatca tcatggatgg taatggacgc
    20821 tgggcgaaaa aacgcttaaa gccgcgtgtc tttggacata aggcgggtat ggacgctttg
    20881 caggaggtaa cgattgcagc ttcagattta ggggttaagg tgttaacagt ctatgccttt
    20941 tcgacagaaa attggtcaag accacaagat gaggtgagct tcattatgaa cctgcctgtt
    21001 gagttttttg ataagtatgt gcctgagctg cacaaaaata atgtcaaggt gcagatgatc
    21061 ggtgagacca accgcctacc taaggataca ctaaaggcct tggaagcagc tattgctaag
    21121 acaaggcaaa atactggctt gattctaaac tttgctctta attatggggg tcgcgcggaa
    21181 atcaccaatg ctgtcggtct cattgctcaa gatgtcctag acgccaagct gaaccctggt
    21241 gacattaccg aggatttgat tgccaactat ttgatgacgg atcatttgcc ctatctctat
    21301 cgcgatcctg accttattat cagaacgagc ggtgaattgc gcttgagtaa ttttatgcct
    21361 tggcaatcag cctatagtga gctttacttt acgccggtgc tgtggcctga ttttaaaaga
    21421 gctgaactac taaaggccat agaggattat aaccatcgtc atcgccgttt cggtgctatt
    21481 taaggagaga gtatgagaga acgtttcatt tggggtggtg ttgcagctgc tgttttccta
    21541 ccctttttac tcattggcag cttacccttt caattgtttg taggtgtgct tgccatgatt
    21601 ggtgtatcag agctgttaag aatgaagagg cttgaggtct tttcctttga gggtgttttt
    21661 gccatgctag cagctttcgt tttgacagtg ccgttggatc attacctgac ctttttgccg
    21721 atggacgcta gttttgcttg ttacgggctg ttggtgtttt tccttttagc aggaatagtg
    21781 attagcagcg attcttatgg ctttgaggat gctagctttc cgattgcagc tagcttatat
    21841 gttggtattg gctttcataa tctggttaat gcgcgaatga cagggataga caaggttttt
    21901 ctggctcttt ttattgtctg ggcgactgat attggagctt acttgattgg gcgccgattt
    21961 ggtaagcgaa agctcctgcc aaaaatatca cccaacaaaa caattgaggg cagccttggt
    22021 ggtatagtca gtgcggtgct tgtttccttt gtgtttatgc tctttgataa ggctgtttat
    22081 gctcctcatc attttggaac aatgttgatt ttggtggctc ttttttctat ttttgctcag
    22141 tttggagatt tggttgaaag tgctgtcaaa agacatttcg gagttaagga ctcaggcaaa
    22201 ttgattccag gccatggtgg tattttagat cgttttgatt cgatgatctt tgtttttccc
    22261 attatgcatc tatttgggtt attttaaagc tcattatcaa tagactgaaa ggaaatctat
    22321 gttaggaata attaccttta ttattatttt tggtattctt gtgcttgtcc atgagtttgg
    22381 ccatttctat tttgctaaac gatctggtat tttagtcaga gagtttgcta ttggcatggg
    22441 accaaaactc ttttcgcatg ttgatcagca aggaacgctt tacacgatcc ggctattacc
    22501 gcttggtggc tatgtgcgaa tggcaggctg gggtgatgac acaactgaga taaaaacagg
    22561 aacgcctgct agcttaacgc ttaatgatca gggcttggtc aagcggatta acctgtctca
    22621 gagcaagctt gatccgacta gcctgcctat gaatgtgact gcttatgact tagaagataa
    22681 gttgacgatt acagggctgg ttcttgatga gatcaagacc tattcggtag accatgacgc
    22741 gaccattgtc gaggaggacg gtacagagat ccggattgcg ccgcttgatg ttcagtatca
    22801 aaacgcaagc attggcggtc gtttgatcac caattttgca ggacctatga ataattttat
    22861 tctaggtatt gttgtcttta ttttgtttgc ctttgttcaa ggtggtgtgg ctgattatca
    22921 tagcaaccat attcgtgtgg tggaaaatgg cgcagcagcc aaggctggta ttagagacaa
    22981 tgatcagatt ttagagatta atcatcaaaa gattaatgac tggtatgagt tgacgcaggc
    23041 cgttactgat tcagcagcag atgttaaggc taagggcaag ctagagatta cctatcagac
    23101 aggtgatcag gttaagacta tagcactgaa gcctgaaaaa aaaggcgatc agtaccttat
    23161 tggtgtccag tacccactaa aaacaagtct gacagacaag ctaataggtg gctttgagat
    23221 ggctggtaat ggtgctctag tgattgtcac tgctctaaag agtttgatta cctcctttag
    23281 cctagataaa ttaggtgggc cagttgccat gtatcagatg tccaatcagg cagcaaagaa
    23341 tggtttagag tctgtcttgt ccttgatggc aatgctctct atcaatttag ggatttttaa
    23401 tttgattccg attcccgcac tagatggtgg taagatcctg atgaatgtga ttgaagcact
    23461 tcgtcgtaag ccattaaagc aagagacaga gacttatatt acccttgcag gtgttgcgat
    23521 tatggtggta ctcatgattg cagtgacctg gaacgatatt atgcgagcct ttttccaagg
    23581 ctgatggtct ctctcattta aaggagagcc taaaaggctt aatgtaacag aaataacaag
    23641 agatatagtg tcattattgt ggttctaaga ccttgcaaat gcagcaaaag cttagccaat
    23701 atagctcatt ttgtctcttt tttagaaatg aattctcaac gaaaggaaag agagctgttg
    23761 accaagctgg gctaaggcct acagctgaaa tcaaaatgct agacctgcta ttagtctaag
    23821 ggcgttttga gctgctctct atagcttatt ttaatgaaac aaagtaaaat gcttatccca
    23881 accctgcgcg aaatgccaag tgacgctcag gtaatcagtc atgccctcat ggtgcgtgcg
    23941 ggctatgtcc gtcaggtatc tgccggtatt tatgcctatt tgccattagc tcatcgtaca
    24001 attgaaaaat tcaagacgat tatgcggcag gaatttgaca aaattggtgc tgttgaaatg
    24061 ctagcacctg cccttttaac agctgacctc tggcgtgaat caggccgcta tgagacttac
    24121 ggtgaggacc tttacaagct aaaaaaccgc gacaaatcag actttatctt aggtcctacc
    24181 catgaagaaa cctttactac actggtgcgt gatgcggtta aatcctataa gcagctgccg
    24241 ctcaatctgt atcagattca atccaaatat cgtgatgaaa agcgtcctcg taatggcctg
    24301 cttcgcacac gtgaatttat catgaaggac ggctatagct ttcatcaaag ctatgatgat
    24361 ttagatgtca cctatgacgc ctatcgtcag gcctatgagg ctatttttac cagagcaggc
    24421 ttggatttca aaggaattat cggtgatggt ggtgctatgg gtggtaagga ttcgcaggaa
    24481 tttatggcta tcacaccgga ccgtactaat ttagaccgct ggctggtctt agacaagtct
    24541 attccgtcat tggctgacat tccagaggag gtcttggaag agattaaggc cgagctggct
    24601 tcatggctgg tttcaggaga ggacaccatt gcttattcaa gtgaatcaag ctatgctgct
    24661 aaccttgaga tggcaaccag tgagtacaag tcctcatcaa aggtaacagc cttagatgat
    24721 ctcgtcgaga ttgagacacc aaattgtaaa accattgatg aagtggcggc ctttcttgac
    24781 gttgctgagc atcaggtcat taaaaccctg ctctttatgg tggaccatga gcctgtgctt
    24841 gctttattgg ttggaaatga ccagatcaat gctgtcaaat tgaaaaacca cctcggtgca
    24901 gacttcttag agccagctag cgaggaggag gcgcgtgcta tcctaggtgc aggctttggt
    24961 tcacttggtc cagttcattt gacagatggt atccgtattg tggctgatcg taaggtccaa
    25021 gaccttgcta atgctgtagc tggagccaat aaagatggtt atcacctgac tggtgtcaat
    25081 ccaaatcgtg atttccaagc agagtatgct gatattcgtg aggtaaaaga gggagagacc
    25141 tctccagata gacatggcgt gctgcagttt gccagaggta ttgaaatcgg tcatatcttt
    25201 aagctgggga cccgctattc tgatagcatg gcagctaata tccttgatga gaatggcaga
    25261 gcagttccga ttgtcatggg ctgctatggt attggggtta gtcgtatcct atcagcagtc
    25321 attgagcagc atgctcgtct ctttgtcagc aagacaccaa agggtgatta tcgctatgct
    25381 tgggggatta atttccctaa agagctagct ccgtttgatg tgcatttgat taccgttaat
    25441 gtcaaggatc aggaggcgca ggacctgaca gaaagagtag aggctagtct gatggccaag
    25501 ggctatgatg tcctcactga tgaccgcaat gagcgtgtcg gctctaagtt ctctgatagt
    25561 gatttgattg ggcttccgat tcgtgtgacg attggtaaaa aagcagctga gggcattgtt
    25621 gagatcaaaa tcaaagcaac aggtgacagc attgaggtgc acgctgatag cttgattgaa
    25681 actcttgaca ttctcacaaa ggacaactaa tgatatgagg tcaacgatgg ttgatctctt
    25741 tttgtatgct ataatgaaag catgacaatt gaggaattac agcagctggt gctagcagat
    25801 catgagctaa tgactattct aagcattata gagaccttgc ctttaaagga ttgttggctg
    25861 gcagcaggtg caattcggaa cgctatttgg aatcatttag cttatgggat aggctttgat
    25921 ccgctgacag atgtagatgt ggtctttttt gaccctgaga tctcttacga agctgagcag
    25981 ctgctagaag agcagcttaa gtgtgcttat cccatgtacc aatgggaggt tcgcaatcaa
    26041 gcctatatgg cagcacataa ccccaagacg cctccttatc gatctagtca agacgctatc
    26101 acaaagtatc cggagcgctg tacagcgatt gctgttagac ttgtaggagg acagctagag
    26161 gtttttgctc cctatggttt agcagacatt agtcactttg tctgtcggcc aacaccgcat
    26221 tttttagagg attcagagcg tatggactgc tataggcagc gcctagcaaa gaaggactgg
    26281 cacaagaaat ggccacagct gacctaccac gactgctaag tcagaggaaa caaagcaggc
    26341 taggagctcc gtacagccaa gcaattagtc cgctcccaga cccgttagct acagctctca
    26401 cctagtcaaa acaagcacat gaacagatca ttggcagata gccttgcctt tgcagatatt
    26461 gtcacaccct atttagctgt accatgtgtc ttatgatagg cgtgatagtg ctgtcagaag
    26521 cgccagctga gccagaaaaa gcgttaagcc tacagcaagg ggcttttaac ctttggtatg
    26581 ttgtcttgta ggagaggtcg aaaatgatca ctatttatga taaaatagac cctaagaaaa
    26641 tcaggagaaa gctatgtcag atttattcgg taaattgatg gaacaaattg aaatgccact
    26701 tgagataaga caatcaagtg ccttttcgtc tgctgatatt atcgaggtca aggtgcattc
    26761 agtgtctcgt ctgtgggaat ttcatttttc ctttgcagag gttctcccga tagagagcta
    26821 tcgagagctg tcagataggc ttgtgagaac ctttgaggca gcagatatta aggtaacatt
    26881 tgacatcaag gcagagacaa ttaattattc ggatcagctg ctgcaagcct actatcaaga
    26941 agcatttgag catgagccct gtaatggggc tagcttcaag tcatcttttt ctagacttca
    27001 ggtcaggtat gaccatcatc agctgatcat tatggcacct gactttgtga ataatgatca
    27061 ctttaggaaa aatcatttac ccaatctggc agctcagttt gagcgctttg gctttgggag
    27121 gctagcgatt gatatggtgt ctgatcagga gatgacagac catttgacaa aggactttga
    27181 gaccaaccgt caggctctgg tggaaaaggc tgtacaggat aatatcgcag cacagcaatc
    27241 attggaggcc atgcagccac cagctgagga ggcagcacca agcccaagcc ttgactatag
    27301 agagcgtatg gctcagcgcc aagcaagctt tgataaggcg gtcattacac caatgattga
    27361 ggtggataca gaagaaaatc gcattgtttt tgaaggaatg gtctttgatg tggagcgcaa
    27421 gacgacaaga acaggccgcc atatcatcaa cttcaagatg acagattaca cctcctcctt
    27481 tgccatgcaa aaatgggcca aagatgacga tgagctcaga aaatttgatc tgattgcgaa
    27541 gggagcttgg ctgcgcgttc agggaaatat cgaaaacaac cccttcacca agagcctaac
    27601 catgaatgtg cagcaggtta aggcgattgt tcaccatgag cgtaaggatc tcatgccaga
    27661 agggcaaaag cgtgttgaat ttcatgcaca cactaatatg tccacaatgg acgctctacc
    27721 gacggtagaa gacctgattg atacagcagc caggtgggga catcaggcag tagcgattac
    27781 tgaccacgct aatgttcaga gctttccgca tggctatcat agagcacgca aggcaggaat
    27841 caaggcaatc tttggcttag aggccaatat tgttgaggat aaggtaccta tttccttcaa
    27901 tcctgtcgct atggacctgc atgaagccac ctatgttgtc tttgacgtgg agaccaccgg
    27961 cctttctgcc atgaacaatg atttgattca gatcgcagct tccaaaatgt tcaagggaaa
    28021 tatcattgag cagtttgatg agtttatcaa tccaggccac cccttatctg cttttacaac
    28081 agaattgaca gggattacag ataatcattt ggtaggagct aagcctatac agcaggtgtt
    28141 agaggcattt caggcctttt gtcagggcac tatcctagtt gcccacaatg ctagctttga
    28201 cgtgggattt atgaatgcca actacgatcg gtatggttta gcaaaaatca gccagccagt
    28261 tattgacacc ctggagcttg ccagaaacct gtaccctgag tataagcggc atggcttggg
    28321 ccctttgact aagcgctttc aggttagcct tgagcaccat cacatggcca attacgatgc
    28381 tgaagcaaca gggcgtttgc tctttatctt cctaaaggaa gctagagaaa agcatgggat
    28441 tacaaacctg cttcagctca atacagactt agtggcagag gattcctata agaaagcacg
    28501 gatcaagcac gccacgatct atgttcaaaa tcagctaggt ctcaaaaaca tgtttaagct
    28561 ggttagcctt tcaaatgtga aatattttga aggtgtgcct agaattccaa gaaccgtcct
    28621 tgatcagcat cgtgaaggct tgctgcttgg gacagcctgc tcagacggcg aggtctttga
    28681 cgctgttttg acccaaggaa ttgacgctgc tgttgatctg gccaaatact acgattttat
    28741 cgaaatcatg ccgcctgcaa tttaccagcc cttggtagtc cgagagctaa tcaaggatca
    28801 agcaggagtt gagcagatta ttcgcgattt gattgaggtc ggccgcagag ctgaaaagcc
    28861 tgtcctagct actggaaacg tgcactacat tgagccagag gacgccatct atcgtgacat
    28921 tatcgttcgt agtctagggc aaggtgccct gattaaccgt actattggcc gcggagaggc
    28981 tgccaagcct gtcccgctac cagaggctca ttttagaaca accaatgaaa tgcttgatga
    29041 ttttgccttt ttaggtcagg acttggccta tgaggttgtg gtgcaaaata cccaagccct
    29101 tgctgatcga attgaaaagg tggaggttgt taaggatgat ctgtacaccc catatattga
    29161 taaggcagaa gaaaccgttg ctgagctgac ttatcaaaag gcctttgcta tctatggcaa
    29221 cccacttcca gatatcattg atctgcgcat tgaaaaggag ctaacgtcca ttttgggaaa
    29281 cggctttgcg gtgatttatc tagcctcaca aatgctggtt aatcgctcta atgagcgtgg
    29341 ttatctggta ggctcacgtg gctctgttgg ttcaagcttt gttgcgacca tgattggcat
    29401 cacagaggtc aatccaatgc cgcctcatta tgtctgccca agctgccagc agtcagagtt
    29461 tatcacagat ggctcggtcg gctctggcta tgatttgcca aacaaggcct gtcctagatg
    29521 tgggacgctg tacaaaaagg acggacagga tattcctttt gaaaccttcc ttggctttga
    29581 tggtgataag gttccagata ttgatttgaa cttctcagga gatgatcagc ccaatgccca
    29641 cttggacgtt cgtgatatct tcggggaaga atacgccttt cgtgcaggta ctgttggtac
    29701 tgtcgctgaa aaaacagcct atggctttgt caagggctat gagagagatt atggcaagtt
    29761 ttacccagat gcagaggttg atcgtctagc tgctggtgct gctggtgtta agcggacgac
    29821 tggtcagcac cctggtggga tcgttgttat ccctaactat atggacgttt atgattttac
    29881 acctgtgcag tttccggcag atgatgtgac agcctcatgg cagacgaccc actttaattt
    29941 ccatgatatt gatgaaaatg tcctaaagct cgatgtactc ggtcatgatg atcccaccat
    30001 gattcgtaag ctgcaggatt tatcaggtat tgatccgatt actattccag cagatgatcc
    30061 tgacgtgatg gcactttttt ctggaacaga ggtgctcgga gtgactcctg aacaaattgg
    30121 aacaccaaca ggtatgcttg ggatcccaga gtttggaacg aactttgttc gtggcatggt
    30181 gaatgagacc cacccaacga cctttgcaga attgctgcag ctatcaggtc tatcgcatgg
    30241 aacggacgtc tggctgggta atgctcagga tctgatcaaa gaaggcattg ccaccctaaa
    30301 aacagttatc ggttgtcgag atgacatcat ggtttacctc atgcatgctg gtctagagcc
    30361 taagatggcc tttaccatca tggagcgtgt gcgtaagggg ctctggctaa agatttccga
    30421 ggaggagcgc agctcctata tcaaggccat gcggcaaaac aacgtcccag actggtacat
    30481 cgaatcctgt ggtaaaatca agtacatgtt ccccaaggct cacgctgccg cctatgtttt
    30541 gatggcattg cgagtggctt atttcaaggt tcatcacccc atcatgtatt actgtgctta
    30601 tttctctatt cgtgccaagg cctttgagct caaaaccatg agtggtgggc tagctgctgt
    30661 caaggctcgc atggaggaca tcagcaacaa gcgcaagcgc aatgaagcct caaacgttga
    30721 aaatgacctg tttaccactt tagaaattgt caatgaaatg cttgagagag ggtttaagtt
    30781 tggcaagcta gacctttaca agagcgaggc aactgagttt caaattgaag gggataccct
    30841 aattccacct tttattgcct tagaaggctt gggagaaaac gttgctagac aaatcgtcaa
    30901 ggctcgccaa gatggtgaat ttctatcaaa aatggaatta cgcaagcgtg gtggtgcttc
    30961 tgccactcta gttgataaga tggacgagct gggcatttta ggaaatatgc cagatgacaa
    31021 tcagctgagt ctatttgatg actttttcta agattgcaca gccctaatat tgtctatgtt
    31081 agcttgtcat acagtgaaga gcagggcagg aaggcttcct gtcctctttt tgtcaatacg
    31141 caaagaaagc ccaaaaaaga acgaggaaaa gcatgaatga attagacaaa aatcctgcct
    31201 taaaggcaat ggttgttttt agaaaagcac agcgtacctt agatgctcaa agctccgcct
    31261 tttttcaaaa ggccaatctg actcctaccc aatttagcgt cttagaggtg ctttattcca
    31321 aaggaagcat gagaattaac aagctcatcg gttctctctt ggcaacctct ggcaatatga
    31381 ccgtagtgct gaaaaatatg gagagaaatg gctggatcag ccgctgccaa gatgctaaag
    31441 ataagcgtgc ctgcttggta cagctaacgc cagagggcaa agccttgatt gagactatcc
    31501 tacctgagca tatcaaacgt gttgaagccc ttttttcagt gctgacagag actgagcaaa
    31561 aacaattgat tacgctttta aagaaattta aagaactcta agcaaatggc tttacaggat
    31621 ctcccaagta ggatataatc actacatagt acaaaaagat actaactagt cataataagt
    31681 catcaagaca gcagatggct agttaccaga taatcaatgg gagacaaagc atgaaacaaa
    31741 ttttaatcat taatggttca ttacggacag gttcatttaa tcatcagctt gctcaagcgg
    31801 ctgagcagct acttgaaggc aaggcagctg tatcttactt ggactgggaa caggtaccta
    31861 tgtttagtca ggatttagaa gcaagcaccc ctgagtcagt ggcaggcgta cgagaagcca
    31921 ttcaagcagc agatgctatc tggatttttt cacctgtcta taattttgca atcccgggct
    31981 ctatcaaaaa cctattagac tgggtatcac gcgcccttga tttgtcagac ccatcaggac
    32041 catcagcaat caatggtaag gtagttaccg tatcatctgt tgctaatggt gggcacgagc
    32101 agctatttgc gcaataccag gacctgctgc cctttatccg tacgacagta gttggtaact
    32161 ttaccaaagc cgctgtcaat ccagaagcat gggcgacagg tgttcttgat atttctgagg
    32221 aaacaaggca aagccttgca gcacaggcag aagcccttct tgaagccatt cactaagact
    32281 ctctgagcat taaacagata aagctgcagc taggatcaaa aagcagctag acacataaaa
    32341 agagcttaaa ccagaaatgt acggcactcc aaaagctaga caaaaactct agcgattggg
    32401 gtacaggtca aaacggtttt aagctctttt ttagacttat tttatagtag taacttaatt
    32461 aagaattagc ataccctctt tagcctcaaa ggggtttttc gcattaatac ggtcatagaa
    32521 taagacacca ttaatatgat caatctcatg ctgaaccacg atagcattgt agccctttag
    32581 cttaatgcgg tgcttttcat tgtgcttatc gtaatattcc actgtcacac gcgcatgacg
    32641 gacgacatag ccttccacca cacgatcaac agacaaacac ccctcaccgt cagcaagagc
    32701 agcgtcttga acagaatgag acacaatttt aggattatag agcacttcct ccatgctgta
    32761 agcctcctta ggtggattgc cctcgctgtc ttcaggattt ggaaccagaa cagcgatgat
    32821 acgctttgac acatcaatct gaggtgctgc tagaccaact cctgctcgaa gccctaattt
    32881 ttctcccatg acagggtctt gagaatgctt taaaaattgc atcatttttt cacctaaaat
    32941 gatgtcatca tcactaagag gaaactcgac ctccttagcc acagcacgaa gcgtaggatt
    33001 gccttcgcgg ataatatcat tcatatcaat gagatgctgt gctttaatta atttatcttg
    33061 tgcagacatt ttgcctccct ttttttatat ttgataatgg ctttactata tcacaaaatc
    33121 cttattttta aaagataagg caggccagtg atgacgatat tagctaactc tatcagatat
    33181 attaaattat ttaaaaaata gttcgttaat tagcacgaca tatatataag aaatacacag
    33241 gaattctaat aattaataga taaaaaatga taatcgttcg taaataaatc aaacatctaa
    33301 tctaaaaaaa ttatattgtt ctgattgttc ggtaattaaa gcaatagcgc ttgtcgaaaa
    33361 actaatgttc tcttaatatc aggtagccat gccaagggtt ttgtgttaaa gtataggacg
    33421 ttcaaaaaat gaaatggaga gactaatgag aacacaattg aaaaaattgc tggcaggaac
    33481 agcagcaggt accctgctgc tgtttaacct gacctgcgga atgattaatg cttttgcaga
    33541 gcagtattac gggtggagtg acgggagtag cagctatccg agtgctttgt atgttacacc
    33601 ggtaggagat actacgaaaa agatagctat tcctgtttat tgctttgact ataagtttca
    33661 ggagccactt gcttggaaag aaataactca accgtcacac ttgattgtct atgataagta
    33721 tgatggcaaa aatttgatgg cagcactggt tgaaaaacct aatatggtaa gctatgagac
    33781 taaaactaaa cttcaaacac ttttaaagac aaagtcaaat ctaataactg caattttaag
    33841 tagaggttat ccaaacaaaa gtttttttga taagtataaa aaattaactg atgaagataa
    33901 aagacgagtg acacaatgtg ctctttggta tcatactgac aatatttcag aacaagatct
    33961 tatcacaaaa catttggatg gggattcagg tgaaaaaagt caagcgctaa aggagttaat
    34021 aggggttgta aaaaatactt ctaatgagtt aggagaggga ttaaccttct atactcgtta
    34081 taatgataga tatggtccta aatatcaaaa cctaataggc tcaattattg ttcccgaaga
    34141 gcctcagaat gatcttgaaa ttggtggtgg aaatgttatt gatttaaact accaatctgg
    34201 accaatggta gaagaaggtg gtcattcagg tggcaaggaa gaggtcgagg acactaaaaa
    34261 gcctgatgtg attattggtg gtcagggaag cgttactgag actactgagg atactcaaaa
    34321 gggtatgagt ggcagtactg agactcagcc agaggttgag gatactaagc agccacaatc
    34381 agatattatc ctaggcggac aaggcaatgt gattgacaca actgaaaata cccaagaggg
    34441 catgggtggc caatcaggtg atactacaga gactgaggat accaagcagc cacaatcaga
    34501 cattatccta ggtggacagg gcaatgtaat tgacaccact gaaaatactc aagagggtat
    34561 gagtggttcc aacaatggtc aaacatttga ggaggacaca cgtcctaagc tggaattcca
    34621 ttttgataat gaagtgccta acgatgatga cgctcctaaa ccagagcaac cagaacagcc
    34681 agagaagccg gagcaaccaa ggaagccaca gcaggagcag caaagcctac cacgtccaat
    34741 agagggcaac cagtcattgc caaaaacaca tgaggcaaaa ggtgtactgg ctctagtagg
    34801 agtaggaatc cttgctatgc taggactagg cttttggttt agaccttatc aaaaagacta
    34861 aatcaaggct cagcagctat ttaagctaaa cagctgtgct cagctaaatg ataaaacaat
    34921 taagattgga gaatgtggct attagtagct tctccaatct tttttgatag cagcatgtgc
    34981 tttttctgcc gtattttatt gagaataata gttgaccagt ctaggcgatt ttgctagaat
    35041 agagaggtcg caagacagac taactttttc ttggttttag gagtgccaac cctaaaactc
    35101 ggattaagca aaaaaggaga attattatgg caatctcaaa agagaaaaaa aatgaaatta
    35161 ttgcacaata tgcacgtcac gaaggtgaca caggctcagt tgaggttcag gtagctgtcc
    35221 ttacttggga aatcaaccac ttgaacaacc acatcaagga gcacaaaaaa gaccacgcaa
    35281 cttatcgtgg attgatgaaa aaaatcggac accgtcgtaa cctattagca tacctacgtc
    35341 gtacagatgt taaccgttac cgcgagttaa tccaatcact tggacttcgt cgttaattgg
    35401 cttgacagag gtcattttag agataaccaa gttctattga aaaaagatct gct
//
LOCUS       DARYVE010000018        32971 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYVE010000018 DARYVE010000000
VERSION     DARYVE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32971
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(310..909)
                     /locus_tag="TVW25_000784"
     CDS             complement(310..909)
                     /locus_tag="TVW25_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1378436.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(1487..3433)
                     /locus_tag="TVW25_000785"
     CDS             complement(1487..3433)
                     /locus_tag="TVW25_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1378437.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TVW25_000786"
     CDS             complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TVW25_000786"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1378438.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(4338..5051)
                     /locus_tag="TVW25_000787"
     CDS             complement(4338..5051)
                     /locus_tag="TVW25_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1378439.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(5486..6409)
                     /locus_tag="TVW25_000788"
     CDS             complement(5486..6409)
                     /locus_tag="TVW25_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1378440.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(6421..7479)
                     /locus_tag="TVW25_000789"
     CDS             complement(6421..7479)
                     /locus_tag="TVW25_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1378441.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(7611..8603)
                     /locus_tag="TVW25_000790"
     CDS             complement(7611..8603)
                     /locus_tag="TVW25_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1378442.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TVW25_000791"
     CDS             complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TVW25_000791"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1378443.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TVW25_000792"
     CDS             complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TVW25_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1378444.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(11117..11356)
                     /locus_tag="TVW25_000793"
     CDS             complement(11117..11356)
                     /locus_tag="TVW25_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1378445.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TVW25_000794"
     CDS             complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TVW25_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1378446.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(12069..12686)
                     /locus_tag="TVW25_000795"
     CDS             complement(12069..12686)
                     /locus_tag="TVW25_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1378447.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(12679..13902)
                     /locus_tag="TVW25_000796"
     CDS             complement(12679..13902)
                     /locus_tag="TVW25_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378448.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(13914..14624)
                     /locus_tag="TVW25_000797"
     CDS             complement(13914..14624)
                     /locus_tag="TVW25_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378449.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(14624..15886)
                     /locus_tag="TVW25_000798"
     CDS             complement(14624..15886)
                     /locus_tag="TVW25_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1378450.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TVW25_000799"
     CDS             complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TVW25_000799"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1378451.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TVW25_000800"
     CDS             complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TVW25_000800"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1378452.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(20909..21844)
                     /locus_tag="TVW25_000801"
     CDS             complement(20909..21844)
                     /locus_tag="TVW25_000801"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1378453.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(21902..23161)
                     /locus_tag="TVW25_000802"
     CDS             complement(21902..23161)
                     /locus_tag="TVW25_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1378454.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TVW25_000803"
     CDS             complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TVW25_000803"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1378455.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            24060..24674
                     /locus_tag="TVW25_000804"
     CDS             24060..24674
                     /locus_tag="TVW25_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1378456.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(24755..25645)
                     /locus_tag="TVW25_000805"
     CDS             complement(24755..25645)
                     /locus_tag="TVW25_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1378457.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(25635..26093)
                     /locus_tag="TVW25_000806"
     CDS             complement(25635..26093)
                     /locus_tag="TVW25_000806"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1378458.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(26321..27250)
                     /locus_tag="TVW25_000807"
     CDS             complement(26321..27250)
                     /locus_tag="TVW25_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1378459.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TVW25_000808"
     CDS             complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TVW25_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1378460.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(27972..28304)
                     /locus_tag="TVW25_000809"
     CDS             complement(27972..28304)
                     /locus_tag="TVW25_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1378461.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TVW25_000810"
     CDS             complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TVW25_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1378462.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(28665..28739)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(28861..30054)
                     /locus_tag="TVW25_000811"
     CDS             complement(28861..30054)
                     /locus_tag="TVW25_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1378463.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            30319..30936
                     /locus_tag="TVW25_000812"
     CDS             30319..30936
                     /locus_tag="TVW25_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1378464.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(31234..32463)
                     /locus_tag="TVW25_000813"
     CDS             complement(31234..32463)
                     /locus_tag="TVW25_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1378465.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(32498..>32971)
                     /locus_tag="TVW25_000814"
     CDS             complement(32498..>32971)
                     /locus_tag="TVW25_000814"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1378466.1"
                     /translation="EVNLGLNGLAGVLFYLSSISYDNEIIEKGIDFILESLVEDSDGN
                     RGVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLSESLLVEFAQFSGLWNGM
                     LGIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQYEFRYAVSIFNQVK"
BASE COUNT         9956 a         7655 c         5870 g         9490 t
ORIGIN      
        1 aatcaaaaga agatagcatt tctgctatct cactgttagc cactacttac aggtaaaaat
       61 acaccttgtc tatttgtagt ttaactatcc atttaatcca tcaataagcc aaaccagacc
      121 gtttaatcat ctacccagcc ttacacatag tattttctca catcatttgt agaattgctt
      181 tctccttgca tgtcaccatc tcgtcttaaa cgttcgtaaa gggctgtttg atcttttcta
      241 actattttag aaaattattt tgctgttctg atgaggttaa tctcgttaga tcagtcatgc
      301 tggaggtagc taccgtatgg gagcgtcaaa ataagtcagc tgataatccc ctataatacg
      361 attgagcttt tcgccatagc tagtatctgt ggcatatgtg cctgttaaac tagcggtggc
      421 ctgctgataa cttgtatgaa tacctcggtg agtagggcga taaagcgggt cactcaaaac
      481 cctagcataa tcctcaaagc aggctgttaa gctgccatag gaccgaaaag aagcgtcaat
      541 tagataaagg ttgccttggc catcatcttc caaggtaggt aaaataactg attttccttt
      601 atagcttcct ttgataccaa aaaaattata atagggctct tgacttagct tagattgacc
      661 atttgctgac tccaaaatag cctgtgccat catgactgag gcatagagct tgtttcgctg
      721 cgcaactgcc tgagcggaat gactaatctt gctcacaaat agcatggttg agctattggc
      781 atgaggctta aggtgatcct tagctgacgc taaggtccaa aggctaagca acatgctgcc
      841 taaaacaata ccagcagcca gccaagagct agcttccctg tggcttcttc tagctttcct
      901 cctcttcaac agaaatatcc tcacttcctt gcttttaaac ctagtatagc aaaaattaaa
      961 agcaaaatgt agccagacca catgctcacc tcaaaaacag gccttatgac ttctaaaaag
     1021 acctagcagc cacaacaggc gcataaaaag tttttaacaa gaaaagaaga ctttgctgta
     1081 tttcaatcca cgctcctgca aagggagcga tacaaaaaat aaatggaata tctacaatca
     1141 aatgatttca atgtttagct atttcaagaa tatatcttat ttttgataga tgttactata
     1201 ggaaaaacgt tgatagtatc tactttaatt gatactataa ttcgaaaata actgtttcgc
     1261 acgtttggtg tggcttagtt tagcagggct attgggtcac tgcttagcta ttctagatca
     1321 gattgattct ctctaaatat tagcttttcg ccagtcatca ctactagcaa caaacaaaac
     1381 gcacgacatc atgtaaaaac aggctgatgt catgcgtctg atgttttatt aagactaggt
     1441 ctaattcaga agctttccct agtacttgtg gctttatagc cagtaactaa gcttttttac
     1501 gaagtgcgcc aaagagaata ccagaaacca ctgctccaat agcgacaaac aataggtata
     1561 agaaaggatt gcttgtcaaa gcgataacga agataccgcc atgtggtgcg attaatttga
     1621 cacctgctag accaacaaga gcacctgtta gggcagagcc agcgataaag cttgggatag
     1681 cgcgtgctgg gtctgctgca ccaaacggaa tggctccttc tgtaatgaag gaaagtccca
     1741 taataatgtt ggtcaagcca gattcacgct cttccttggt aaatttgtct ttaaataaga
     1801 gtgttgccac aaaaacagct agaggaggca ccataccacc tgccatgaca gcagccataa
     1861 caactgaccc accgcttgca acggttgcag caagtgttcc tgtaccaaag acataggctg
     1921 ccttattcac tggaccaccc atatcaacag ccatcatgcc gccaacaaga agtcccataa
     1981 gaactgcaga gctacctgac agactttcta agaagtggtt caatgctgta ttgatagctg
     2041 ccataggaat attgatcagc agcatcaaaa gacctgtcac aagaacacca agtaatgggt
     2101 aaagaaggat tgacttgacc ccttcaagcg aacgcggaag ccctgcaagc acttgacgaa
     2161 gagcaagaat tactccccct gcaaggaagc cacctacaag cgcaccaaga aatccagacg
     2221 gtactcccgc taatgatagg ctagcctcac cgccagcagc aaatggaacc tttccaaaag
     2281 caagaccgct agaagcaatg gcacctgcca caaagcctgc cacaagacct ggcttttcag
     2341 cgatagaata agcaatgtag cctgctagca ctggcaacat gaatgaaaag gccgcaccac
     2401 caatatgttt aaagatagct gctatttcat ggtaggatcc caaattagac agctgatcct
     2461 ttggtacccc aagcatgttg tcaagcaaga aggcaagagc aattaggatt ccaccaccaa
     2521 ttacaaatgg cagcatttgt gatacaccac tcatcaggtg cttgtagaag gctccgccta
     2581 ggcttgtctt ttgagctgct tttgcttgtt cagcagcgcc attcttggca tgataaacac
     2641 taccagcatt gtttaaaatc agtgaaatca attcctcgct tttcttaata ccatctgcta
     2701 caggacgagc aatcaattgc ttaccatcaa agcgatccat ctcaaccgcc ttatcagcag
     2761 cgataatcac tcccttggcc tgcttgatgt catcagctgt caggcgattg ccaacccctg
     2821 aagcaccgtt ggtttcaacc ttgatgccga cacccatctg tgcagcctgc tttttcaagg
     2881 cctcttctgc catataagta tgtgcaatac ctgtcgtaca agctgtcaca gcaacgataa
     2941 actcctgagc atttgtagga acaaaagcta cctctttctg atcagaagcc gcatcaaaga
     3001 cagcaatcac ttcgtctgga cttgttgcct ttcgcagttg atctgcaaag ccatccttta
     3061 ataggtattg ggataattcg gctaaggccg ctaagtgagt atcatttgcc ccttgaggtg
     3121 ctgcaatcat aaagaacaga tcagttggct gaccgtctaa ggatttgtaa tcaacgccct
     3181 tgttagattt tgcaaagagc actgctggct ggtcaacaac aacatttttt gaatgcggca
     3241 tagcaatgcc atcgccaaga cctgttgagg tttgctcctc gcgagctaag atactctttt
     3301 taaacacatc aaagtcatgt acaatcccat gctctactag ttctgtaatc atttcatcaa
     3361 ttgcagcctc ttttgaaaca gcctgcaaat caagaatcat gatgtctttt cttaataaat
     3421 cctgtatttt catcgaacct ctacctcaac ctcattatat gtttttttaa tatcatcaat
     3481 tgctgctaaa tcatctgaaa aagcagttgc tgttccgcag gccactcccc attttagagc
     3541 ctctagcgga ctatgacttt tgacaaaggc acctgtaaag cctgccacca tcgaatcacc
     3601 agctccaaca gaattcttca cctgcccttt aataggctta gcaaaataag ttgcttcctg
     3661 agtgaccagc aaggcaccat caccagccat cgaaacgata acatgctgcg ctcccatgtc
     3721 aaggacctta cgagcatatg tttcaacgtc atctagccca tttaagctga cgttaaaaat
     3781 agcttctagc tcatggttat taggctttac gagcaatggg tgatacgcca atgcatctag
     3841 caaggtctgt ccttcaaaat cacagaccac ctgtgcccca gcttgtctga ccaatgggat
     3901 caagtcctta tagacatcat tgcctagact tgaaggcgct gagcctgcaa aaacaacaat
     3961 gtcctctgct gacacatttg ccaatatagc ctttaaatga tccaattgct gctttgaaat
     4021 cactggtcca aggccattaa tctctgtctc ctctgctgat ttgatcttaa cattgatccg
     4081 cgtatcctga tcaaccgtta caaagtcagt attgatgctc tcagcagcta gactttcctt
     4141 aataaaacgc ccagtgaagc cgcctaaaaa gccagtcgct gtattatcaa tgcctaatcg
     4201 ctgtagaatg cgactaacat taatcccctt tcctcctgca aatgtatcgt cactgaccat
     4261 gcggttaacc gctccaatat ctaattggtc tattctgaca ataaagtcta tagaaggatt
     4321 taaggttact gtgtaaatca tagtgcaatt accttcgctt tttccttgat tttcttcagc
     4381 attactgtcg aagatttctc tgtaatgatt tcaaccctat caattggagc aaccttgaca
     4441 aaggaaacat gaccaagctt tgttgcatca gctaatacat aggtgatttt agcattggca
     4501 atgacagctt ttttaataac agcctcctcc atatccggag tggttaaaaa tgcctcatcg
     4561 ataccattga taccaagaaa agccttatca aaattcattt gcctaatttg ctccaaggca
     4621 acatgaccga tgcttgcgtc tgttgtctgc ttgacatagc caccaataat aatggtcttg
     4681 atcgccatat caaccagtct agtcgcatga tgaatagaat tagtcactac tgttactttt
     4741 tttaattgca aaaaaggaag gagaaattcg gttgttgtcc cagcatcaat aaagatgaca
     4801 tcattatcaa aaaccagctc tgctgccttt tgagcgatga tttcttttat ttgactgttt
     4861 ttgacagatt tttcctgatt agataattcc tcttgtaagg aatgaaaaag ctcggcacct
     4921 ccatgcactc gatgaagctt gccctcacgc tccagctcat ctaaatctct acgaacagtt
     4981 gattctgacg agcttaacag ctgcattaaa tcctctagcg caacgtaatt ctcagctgtg
     5041 atttttgcca taatgagctg ttttcgtttt gattttaaga taaaaccacc cctttgtctg
     5101 aaatcgttta cagctctatt atactacact ttattccaaa gtcaagcact atcttttaaa
     5161 aacattcaaa ttcaatctta gacctctatt gccttaacaa taactgccaa ttgatcagtc
     5221 attgtccccg tcaatacctg tagactaatg attaacgact tttttattaa ctagagccca
     5281 aaaagcgctc acctgttgca aaagtctgaa acacaatagt ctcttacaaa tcaaaaagca
     5341 acggatttac tgtcgttgct tcataatgag agtctaggac aaagtctttt cagccaacaa
     5401 gacaaaacga gagagtcacc tattgtgagc ctctcgtttt attgtactga gaaattgttt
     5461 tatcccagac tccttatgtc taaacctatt tgatcttcaa aatattctct ttggcatgga
     5521 ctagctgtgt aatcaagcgg caataagggg tatcgatacc aagcttttca cccttggtat
     5581 ttaccgcacc gttgataaag tcaatttcag tcaagcggtg attttgaaca agatcctgat
     5641 gcattgatgg gtagtgatga gcagccttca ctgaggtttc catcacatag gctgtgattt
     5701 cctcttcatt aagctccacc ccctcagcac gaccaacaat aacaaactca tgaatgattt
     5761 ctttaaccat gtttaaacca tcttcgctgg caaataactc accaatcgtg caatcaagta
     5821 gggcacaggt tgagttcatt gtaccattga cacaggcttt tctccaaata tttggaacaa
     5881 cattatcatc ataagttgca ttcaattgag cgtcatttag caagtcagca atctgatgtc
     5941 ctgcctcttg gtttgctgga tccatgcttt gtagattaag cgcaccaact ccttgtaagt
     6001 gtacctgacc aggtccctca agacccgctg tccaaacggt aacacccatt aaaatattat
     6061 gctctggaat atagtgacga atcacatctt cgtgtccaag accatttaat aggcaaagta
     6121 ccttggtttc agggccaata atacctttaa tatcagtcag catttgtggc agctgcatgg
     6181 ctttggtaaa caaaatgata aggtcagctt ccttagtagc ctctgtcggc ttcatgatag
     6241 gaagctttac ggtttcctct acatcgcctg aaatcttcaa gccattctct ttgatcgctt
     6301 gaagatgtgc ttcccaatta tccagtaaaa taacgtcatt gtttgttttt gaaatttggt
     6361 aaccaaatcg acagcccata gctcctgagc ctgcaatata aactaacatg ctttttcctc
     6421 ttatccttca aatacaaaaa tatcttcttt ataaagcttt aaaatatcct tacaaagctt
     6481 atgtgccaca aaagcaactc caaatggaat gaccaaccaa gcaatgataa tgatcacaat
     6541 attgctgcca ccggcaagtg aagcaatagg accaactgca ccaacaagac caaagccaga
     6601 tgaggctggt gttccaatca gattaaacat tggaacggtt aaagagctaa caatagctgt
     6661 catcatcatt ggaatagcca taactgggta ttttaagaag tttggcatca tcattttcat
     6721 agcgccaagg gcaatggcaa ttggaacacc tgatttgtta acctttaacg ttgcccacac
     6781 aagaacagcg gttgttgaag caatacccat tgaggccgca ccagctgcca taccatttaa
     6841 gccgatagct aaaccaatcg caaccgttga gatcggactc acaatcaaaa gagcaaaggc
     6901 aatggcaatc aaaatagaca tcagaattgg ctgaagcgtt gtaaatgaat taatgccttg
     6961 gccaatcagg gtcgtcacat aagaaacgta aggaagcagc ttccagccaa tgtaacccac
     7021 acctgttcca ataataattg gcaacaaaat aatggttaga gacccaaatt tatcaccaaa
     7081 ccacttcact gctaaaacgg caagcgcagc tgtgatcatc atattaatca gatcaccaat
     7141 gccctttagc tggaaggtcc cagtggcaac acctttttgg ataacctctg tataagccca
     7201 agctccagaa ccgatataag ctgccccgcc gacagccagc tgctgcattg ggttaaattt
     7261 gaactgctgt ccaatcaaaa aaccagccat aactggcgta aagaattgga aaacctggac
     7321 gatatgtaaa aattcagctg ctacagtatt tggcaaaagc ggctttaaaa acgtcgctaa
     7381 aatagcattc ggaataagtg caactacaat cgcaattgct gtaccagcta agaccttatt
     7441 cataaacgag ctaaaggtct ctttatttgt tgttgtcatt tcatgacctc tcttaatatt
     7501 atagtgtgaa aaacatcacg aaagtattct aacataaaaa gagcattttg tcacagctat
     7561 tttaattttt atcaatacgt acagaatatt caattaaatg tcatataata ttaatcaatc
     7621 aaggctgttg aatgaacagg tctattatct ctatcaggat aaatatactt aatcgcttgg
     7681 ttgacagcaa tcggtgcctc accaaagcca gtggcaatca aatcaaccct gccttcataa
     7741 gctgctgcgt caccgatcgc aaaaatccct tcctgacttg tttgaaagag gggagagaca
     7801 agaagacttg agcgcttata atctagattc caatgcttta ggtttttatt agatgtagaa
     7861 aagccaaagc taacaatcag gctgtctagc tcaagcgtta tctcctcttc tgactttacc
     7921 ttttgaatag tcattttgtt gacaaagcca ttttctcctt cgagggcaag gggaacaaag
     7981 ggggtaaggg tagtaacatg agagtttttt aacaattcta cgctatgctc atgagcccta
     8041 aaggcgtctc gccggtgcac aagggtaaca ctcttagcga ggccatctaa ggctaaagcc
     8101 cagtccacag cagaatctcc accaccgcag atcacaaccc tcttaccagc aaactgattc
     8161 aagctgtgaa cattataaaa gagattatga tcagcaaata actgctcatt gtctaagccc
     8221 aaggttctag gcgcaaaggc tccattgcca caagcaacaa taatggcctt agaataatgt
     8281 ctggccttgc ttgtttgaat aacaaagttc ccatcagcct tctcaaaaga caggacctct
     8341 tctttcaggc atactgctat gcgatcgtca aatctgctta gctgctcaat aagcttttgt
     8401 gttagttccg ctccagtcag ggccggataa gctggaatat catagataac cttttcagga
     8461 taaagaacag ccggctgtcc tcctagctct gacaggcttt caataatctt aaccgtcatg
     8521 ccgcgcaggc ctgcataaaa ggctgcaaat aagcctaccg gacctccacc aatgatggta
     8581 atgtcatata ttttttcttg cactagttct ctccttcact tagccccgat ttgattttat
     8641 caaaaatcct tttttcctca tcagaaaaat cataagtctc taataaatct ggtcttctca
     8701 aataggtctt ctttaggctt tgctccatac gccagagacg aatatgctca tgatggccac
     8761 tcattaggac atcaggcacc ttcatgccac gataatcata tggccttgta tactgtgggt
     8821 actccaagag cccagatgag aaggaatcct cttgatgact ggcttgcttt ccaagcacat
     8881 taggaatcag tctcactgtt gcatcaatca ttgtcatagc agccagctca ccaccagtta
     8941 agacaaaatc tcccagagat atttcatcgg taacaagtgt cttaatgcgt tcgtcatagc
     9001 cttcgtaatg cccacaaata aaaattaact cttcctcaag agctaattct tcagcataag
     9061 actgatgaaa gggttttcca gcaggatcca gtaaaatcac tcgaggcttt gtagcctgaa
     9121 tgctatccat ggtatcaaaa ataggctgcg ctctcagcag catgccctgc ccaccaccat
     9181 atggctcatc atcaacatgc ctagctttct ccgcatggtc acgaaaattg tggtaatgaa
     9241 tatctaaaag ccccttttcc ttagcctttc caacaatgga gtgctccaaa ggagcaaaca
     9301 tttccgggaa aagggttaaa atatcaatct tcatcatcta agccttccat aatttcaacg
     9361 tctacccgat gcttttcgat atcaacacaa agaacaaccg atgggatata aggaagcaac
     9421 aggtcacgct tgctttgccg tttgaccacc caaacatcat ttgcaccagg ctgtaaaatt
     9481 tccttaatct ctcctactag ctggtccttt tcatacacct ccagaccaat aatctggtga
     9541 tagtaaaatt ctccctcagc tagcttaccc tgattctctt tagcaatctt aagactgtag
     9601 cccttaaatt gctcaatagc attgatgtga tacattccct taaacttgat aatgtcaaac
     9661 tgcttatgct tgcgatgact cgcaatctca acctcctgca caaaacgatc cttgtcgtca
     9721 aacagggcta gtctagcacc tttttgaaat cgttcctcag taaagtcact cacagacagc
     9781 acgcgcattt ctccttgcaa gccttgagta ttgacaatct tcccaacgct aaaatattcc
     9841 atccttactc ctaatcatct tagactctat agcttgatag acctctattt tttcatgaca
     9901 acacgacatg agtatcatca tcctaagcac tctagcctat cgttaaagct ccccttattg
     9961 taacatgttc tgccttattt tgcacttctc tttcaaaaaa ttaatctccc agttatagca
    10021 gctaagccta gcaagcaaag cccttgatgc taaagaatcc tgatccccct ataattaaca
    10081 aatcatcatg acttgccttg cccaagctca gtcaagtgaa tgaaaaatct gctaaacaat
    10141 agccttgcgc ctcgctgaca agcatcaaaa aaacactcct gctggcaatc tgaactgccc
    10201 cccaattgtt agattttatg tccaactttt gggggtcagt acaatctagt aaactagaat
    10261 caggagtgtt tcattatagc ccaacaagca aaaggaatac ttggtaaaag caaagctgac
    10321 ttgcattgag aagattaaaa ccattcaatc tgtcacaata attatggaaa cattgggaat
    10381 ttaaaaacaa gtatcagctg ctatcaacct gtggggaaat agtctaccta tgcctatcgg
    10441 gccatccatc ataggtcctc tcaagaaatg atgagagcct catcaaccag ctatcatcgc
    10501 cttaaaggag aatgacgaat gttatcgtag gtgtcccaag aaatactaca aaagaaactc
    10561 attttgatct taatgctcta aagggcttga ccttacgtca actgataaag ctctacttca
    10621 tagcatcgtt ttgctttgca gcttttctat acctcatgtc taataaaaga cataagcttg
    10681 ccgataagaa cattacccca acatagaaga atagattggt ctcatcgcca gtctttagta
    10741 agatggtatt ttgatgcttc atcggtttgg tagctgttga aacatgcgga cacttggttt
    10801 catttgtcgt cgatggtatt gtcggacgac ttggcttagt gttattaggc ttatgattgc
    10861 cttcactact gcttaccttt ttcttccact gtgcaaacaa ttcattagga aacggcaggt
    10921 cattatctac cctaatgtca tcacctacct tttttaacct cctgctcgat ctcttgttgc
    10981 atacaaaatg ttatacagat acttctgtca gatagagttc ttgcttttgt ctcttgactt
    11041 ggtgattcaa aacacaaaaa aagcctgcta gatagaacta gcaaggcttt aagattagtc
    11101 ttgttcaaaa tagaacttat ttttcatcaa tgactaatcg aacctttttt cctaaagttg
    11161 gcaccgaata gacaatcgat cttatcgctg tgatggtacg acctttcttt ccgataacac
    11221 gaccgatgtc ttgagcatcc aagtcaagat ggtactctaa aaaatccgga gtatcttcaa
    11281 ttttaatagt aagcttatct ggttgtgaaa tcaagggctt cacaatagcg ataatgagat
    11341 tttcaatggt atccataggc ttttattact tagaaaattt ttgatcgtgg aatttagcca
    11401 taaccccagc tttagataga aggctacgaa ctgtatcaga aggttgtgca ccttttccta
    11461 gccaatcaag aacacgatct tctttaagag ttacttgatt ttcagctaca agtgggttgt
    11521 aggttccaac tgtttcgatg aaacgaccat cacgtggtgc acgtgaatct gcaacgttga
    11581 tacggtagaa aggttttttc ttagaaccca tacgagttaa acggattttt actgccattt
    11641 taatatgtct cttttcttta aatgataata gtcaagaaat gtagtcctgc tcatttctca
    11701 cctaactagt atactttact tttgattatg tgtcaagttt ttttcttgac acttttttat
    11761 gatcataata ctactcaaca tcttcaatca gctaagctgc ttagatgaca tcaaacagca
    11821 ggcagctgct cttataagag catacaactc caaactaacc tactctagtg atccttagcc
    11881 gtcaataatg ggatcaggca agcataactc cccgtcaaag gagcggtttg tttcacagca
    11941 aaaaggcgaa ataaactgac aatcacatca aaaaggacga gcccctaaac atgcaggagc
    12001 tcgtcctttt accaatatga cttagtctct ccttgctttt aaggctaggg tattagctaa
    12061 gcgttacact aataatgcat caaaatatgc ttaagaaact ctccaccata aatccaaaaa
    12121 taactgaagg tcaaaattga aatgggtcta caaattagga taatcagtaa aaagcgcttg
    12181 taggtcatct gactcaatcc agtaatcata ataagagcat cggcaggggc taagggggaa
    12241 atcatattga gaataaagaa acgctcaaat aatttcgttg atagcttctt ttcataaaac
    12301 tgtagctgct ccatacttaa aaacagtaag ataaagggct ttccgtatct cctcaccaac
    12361 tgaaacaaaa tagaagatcc aatgcagata ccaaacacat ttaacataaa gcctaatata
    12421 ggaccaaagg ctagaaagcc aacgactgtt gtcacaccac caggaatgat aggaacaact
    12481 acctgcacaa tttgcaagat aaaaaagcaa atggcaccga taaggagatg atccttgatt
    12541 aaatgggcta aagcctttgg attattaata atatctagct gcctaataag gtagacaaca
    12601 agcatgacgg agaacagaat tgataggcca ccaagaatct taaacagctt ctttaacaac
    12661 gaatgtgaaa caccaaagct actcatagcg caaagcctct atcggatcaa gcttgcttgc
    12721 tttgtttgct ggcagcaatc caaaaataat accaattgat gccgaaaaga taatagctac
    12781 agccgcaaca tctaaggaaa cagctgctcc ctttaattgc atcgcatttc ctagcacacc
    12841 tacacacatc tgtgctagca gcagccctaa aagaccgcca attaacgtca acaccactga
    12901 ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct cccaaggctt ttcgcaagcc
    12961 aatttcacgt gtacgctctg ttacagatac cagcatgatg ttcataacac caataccacc
    13021 cacaagaagg gaaattcctg caatggaccc aacaactgtg gtcatgatac taaattgtgc
    13081 gttaatgtca ttgataattt ggctattgtc aggaacagcg tactcgccct ccttaacatg
    13141 agacagtgtg gtcagcatag cagctgcttg atttcctaat tcaaggcttc gcttaacgtc
    13201 gccaatataa agataaacag agccaatttc cttgacatga aattctgaag ccacctgggt
    13261 attggccata atggctcctc cagaaatccc accagcaaac gaaacaacct cctgatcagt
    13321 cttgtaaaca cctactacaa ggtagtcctt actatctaga ctaaccacct tatttagagc
    13381 ttgttcataa ttgcctttgc caaataattc gtcagccaag acagtatcta ataggataat
    13441 gcgagaaaaa tttttataat ccttgctatt tagcgtccta cctgcaacaa tatcatattt
    13501 tttgacttta aaataatcct gactaacccc agtgatggcc acattgtcca tcttcttttt
    13561 ctcaaaggaa atggtagagg ttgaattatt ggtatagtaa taagaatcta ccccatcaat
    13621 tgctttgaca atctgctcta gccattcagg cttgacctct tgctcatttt catgcgctgc
    13681 aaaggccgcg taagggttgt cctcatctcc ttttgccttg aaataaagct gaacctcttt
    13741 ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg gcagcaccaa gccccatgat
    13801 aatcacaaca gcagctacac cgataataat tcccagcatg gtaagaatcg aacgcagctt
    13861 gtgcccccag attgaactaa gagcaaattt ccaattttcc atcacttttc ctcctagtca
    13921 atcctgacac tttctgttgt atcagctgtg atttcaccat cacgaataac aatttttcga
    13981 gtggcaaagt ccgcaatctc tggctcatga gtaaccataa taatagtttt gccttcctta
    14041 ttcagctccg tcaaaagcct cataatctgc tcaccagtct ttgtatctag ggcaccagtc
    14101 ggctcatcag ctaagataat agacgggtta ttaaccaagg ctcttgcaat ggcaaccctt
    14161 tgcttttgac cacctgataa ctctgatggc aaatgcttca ttcgcatacc aagctcaacc
    14221 ttttccaaaa attgcttagc caattcacga cgctttgata ctccaactcc agcataaatc
    14281 aagggaagct caacattttg cagggcattt agctttgcta gtaaaaagaa ctgctgaaag
    14341 acaaagccaa tctcttcgtt tctcacctga gcaagctttc gatcatttag gatctcaacc
    14401 tgtgtgccat tgagacgata atcacctgag gttggtctat ctaataagcc gatgatattc
    14461 atcagggttg atttccctga gccagaaggc cccataatag cgacaaattc accctcatat
    14521 acagtcaaat ccacgccttt taggacctgt agctcctgat caccattttg atagctttta
    14581 acaatgcttt ttaattgtat taattctttt ttctcatctg gcactactta atcacctcgg
    14641 attctttact gcttttttta gaatcttttg atgcctttgt gtctgcggaa ataacgtctt
    14701 ctagcttttc accctctttg atgttcttat cagggttagc aatgacaata tctcccacct
    14761 ttagacctgc acttacttct tgtctttcag catcagcatt gcctagggtt acttcaacct
    14821 ttttagcctt tgcagttgag tcatcataga cccagacaaa atgcttcttg cctttgttaa
    14881 cgatagcagt aactggtact aaggcatgct ttgcttcgtt gataacctca acagacaccg
    14941 taaagccttg ctttagctgg ttaagcggac tcgtgatatc aattttgtag tcataggtcg
    15001 caccagttga gcttgatgag cctgagcctc ctgcagttga accacctgca ttggcatcgg
    15061 ttgggtagtt tgacacataa gaaatctttc cggtccactc ttgatcagca tagacctttg
    15121 atttaatctt cacagcttgt ccaaccttaa tattggctaa atcatactct gttagggtcc
    15181 ctttgacctg taacttgcct tcggttgcga catgaaccaa ggtttgactg ttttttgaag
    15241 acgggtcaat atcattatta acctctacaa ctgtccctga aacaccactg acaactactg
    15301 tttcatttaa ggcctgctgt gctttattga cctctgcttg agcatcagca taggaatcat
    15361 ttaaatcctg caattgctga gcatagctag cattttgctg ggctgagggc tgaatggttg
    15421 tggtggtttc ttgccctgtc tcctcgtcct tgcttgtctc agtagttgct gctggaacac
    15481 catacgtttt taaatgatta atctgacgcc caattttatt gagattgcga acagcggtgt
    15541 cataagctgc ctgtggtaca gttgtattgt actgtactaa ctgctggcct tgtgtgacct
    15601 gatctcctac cttaaccgta acggtagcgt ctgagccttt gctagcatca aaataaacat
    15661 attcttctga aagagcttta acagtaccag agagtaaggt tgaagaggct attgtccctt
    15721 ctgttacatt taccgcagaa taaggtagct tgatattttg atcagagata gtatcttgct
    15781 gttgcttcca caatactcca ccgataacga ctacagttag tgcaactgca cctgcgataa
    15841 tgcctttggt tttcgttgat aactttatct ttcctctttt agacatttct gtcctcccct
    15901 tttgtactat ttttgtaaga caagtatatg atgtttttaa aaacttgtca agaatttctt
    15961 ggataagctt aataaagcag cctcttcatc atgtagatga caactctatt ataatggttt
    16021 ttcaagctgt actagcttac acttttgtaa tattaaaaag aggcaaagac aaaaagagtt
    16081 gtcctttaac tttattacac agtctcattc attaaaaagc gaacaagcct agttttcaaa
    16141 atctcagaaa actagacttg ttcgtttgtt tagacttttc tctcagtctc ttcatcaggt
    16201 ttaaatagct tctatactaa aggtacggct ttcaagaact ctcagcattg ctactgctgt
    16261 atccaatgct gtaaacagag gaactccttg ttcgattgct gagcttctga tcatctgccc
    16321 gtccttatca gtcactcgtt ttgttcctac ggtattaata atagcttgaa tctgcccttt
    16381 tctcagtaag gctgggatat catgagcatt gtcgccaatt tttccaacta gctgtgaatc
    16441 tagcccttgg tcagcaaaga aagcagctgt gccttcggtt gccatgatct ggtagccaat
    16501 agcactaaag cgtctagcta agatcagagc ctccgactta tggtcatcag cgatggtaaa
    16561 aactattgtt ccatattccg gcatgtgcag atagctagct tcaaaggctt tgtaaagggc
    16621 tttttcaagt gttaaatcag agcccatgac ttcaccagtt gatttcatct caggccctaa
    16681 aaggctatcc accttagcga gctttgcaaa tgaaaaaacc ggtgccttga tatgaacaag
    16741 cgagctttca ggataaaggc catcttgata acctaagtct tttaaggtct gacccagaat
    16801 aagcttcgta gcgacttgtg ccattggaat attggttact tttgataaaa atggcactgt
    16861 ccgactggca cgaggattga cctcaatgac atagacctgc tcattttgga tcacaaattg
    16921 gatattcatc atgccaatac agtttagccc tatagcaaga cgcttagtgt aatcaacaat
    16981 cttgtcttga acctgtttag ataggtgctg cggcgggtac acagccattg aatctcctga
    17041 atgcactcct gctctttcga tatgctccat gatccctggg attaagactg attgaccgtc
    17101 agagattgca tctacctcgc attccttacc aaggatataa gaatctatta aaacaggatg
    17161 ctcaggacta gccttgacag ctgttttcat gtaggagcgt aaatcgtttt cattttcaac
    17221 aatttccatt gctcggccac caagaacata agagggtctg accaataccg gaaagccaat
    17281 ggcacgcgct gcctctaagg cctctgcctc attggtggct gttttcccag gaggctgagg
    17341 gatccccagc tccttcaagg ctttttcaaa aagctcccta tcctcagcac aatctaagtc
    17401 ctctagctgt gtgcctaaaa taggaactcc ggccttggtt aactgctctg ctagattaat
    17461 agcagtttgt ccaccaaact gtaggattac tccctttggc tgctctaatt caataacgtt
    17521 catgacctct tcaaaggtta agggttcaaa ataaagcttg tctgatatcg aaaaatctgt
    17581 tgacactgtt tcaggatttg aattcatgat aatggcttca tagcccgcag cctgaatagc
    17641 cttgacagaa tgtacggttg cataatcaaa ctcaactccc tgaccgatgc ggataggacc
    17701 agagccaagg acgataacag attctttctc ggatttgatt gattcgtttt cccactcata
    17761 ggtcgagtaa aaataaggcg tttgtgagtc aaattcagct gcacaggtat caaccatctt
    17821 ataaactggc aagacacgat aggctcgcct taaccgtcta atacttgcag catcagtttg
    17881 ccaaagctct gcaatttttt ggtctgaaaa accatatcgc ttggcttcta tcagcaaatc
    17941 gatatcaact ggctttttaa taaggtcttg ctccagttct acgatatgac gtaatttatc
    18001 caaaaagaat aaatcaatct tggttaagcc agctagctct tcaatactat agccacgacg
    18061 aagggcctca gaaagataga atagacgatc gtcctgtgct cttacaatgt gagcaaccag
    18121 ctcatgatca ctgatagtat ctagaccctt cagttcgtta tggtgtactc caatttccaa
    18181 cgagcgacaa gcctttaaga gacattcctc aatacggcgt ccaatagcca taacctcacc
    18241 agttgctttc atctgggttc ctagacgacg ctccccccgc tcaaacttgt caaatggaaa
    18301 gcgtggcagc ttggcaacca cataatcaag agctggttca aacatggcat aggtggttcc
    18361 tgtgaccgga ttaagcatgt catcaagcct taagccaact gcaattttag cagctatttt
    18421 agcgattgga taaccagttg cctttgaagc cagtgctgat gagcgagata cccgcggatt
    18481 aacctcaatc acataatagc tgaagctatt gggatcaagt gccagctgaa cattacagcc
    18541 tccttcaatc ttaagggcac gaataattct caagctagca tcacgaagca gctgattctc
    18601 aacatctgat agggtttgtg tcggggcaaa aacgattgaa tctccagtat gtatccctac
    18661 tgggtcaaaa ttttccatac tgcaaacaac cagcgcgtta tcagcagcat cacgcatgac
    18721 ctcatattca atctctttaa agccggcaat ggagcgttca atcagacact gggtgacagg
    18781 agatagcttc aggccattct ccacaatatc tcgcaagacc tcttcattgg agcaaatacc
    18841 acctccagtg cctcccagag taaaggcggg gcggacaata acagggtagc caatggcatt
    18901 tgcaaagccg atagccgcct ctactgtcgt cacaatctct gattctggaa taggctctcc
    18961 caactctttc attaattgct taaataaatc acgatcctct gcctgatcaa tagcagataa
    19021 ggttgttcca agcagctcca ctcctaattc ttgtaaaata ccagccttag acagttccat
    19081 cgccatgtta agaccggtct gcccacctaa ggtcggcagc aaggcgtctg gtctttcctt
    19141 tcttaagata cgactaacaa atgccaacgt caggggctcg atataaacct tatctgcaac
    19201 ctctttgtct gtcataattg tcgcagggtt agaattaacc agaacaacct gatagccctc
    19261 ttcctttaag gctaaacaag cctgtgttcc tgcgtaatca aattcagctg cctgcccaat
    19321 aacaatagga ccagacccta tcaccatgat ttttttaata tctgtacgtt ttgccataat
    19381 atctggtaca aaaggcctta acaatccgaa taaaataatg caagcaccta acattaaagc
    19441 atcacaatct attttttact aggatttgta cctgtactca gctgcagcaa gccctttgta
    19501 cctactcctt tcattatttg ccgtctcaca gggcggcatt aaataaaaca cttaacagtc
    19561 tgtcacatga gacgatgagt acaagatcaa gtaaccctta gctcagcaag tatagatgac
    19621 ttaattgata tagtcttttt acttctaaag agggcgatct tgccagcaaa tactagtcat
    19681 aacccgcggc agagcgatca tttcccacta gtctatctgc tgcctgactc aagctgtttc
    19741 atgacagctg atcaagcctt tggtgcttgc tttttgatct gctagcacac ttgattaaca
    19801 tttgccttgc tgctctagct gccaggcgtc aatcatatct aaaaattcat caaatagata
    19861 gctagcgtca tgagggcctg gtgcagcgtc tgggtgaaac tgcacagaaa aggcgggaac
    19921 atgtcgatgt ctcacccctt caacagtttt gtcattaatc tcctcgtgcg taaccatcaa
    19981 gcagtctggc aagctgtcgc gctcaacagc ataaccatga ttttgactag taaaatcaat
    20041 acgtccggtc gctatttctc tgacagcatg attaaagcca cgatgtccaa aaggcatttt
    20101 aaaggtctta gcgccattag ctaagctaag cagctgatgg cccatacaaa tgccaaaaat
    20161 tggaattttt ccttgaacac cacgaatcat ctccaaggcc tccggcaaat cctctggatt
    20221 acctggacca tttgatagca ttagaccatc tgggttgagc tgtagaatct cttctgctgt
    20281 gatatcaaag gggactattg tcatctgaca ttgccttttg gataattctc ttaaaatgga
    20341 atgcttcaag ccaaagtcca ccaaaacaat atttttccca acacccggag cgggataggc
    20401 agtcttagtt gacacctgct caataccatt agtcggaagc acagttgcac gcagctgatc
    20461 ctttaggtgt tcaagcgtat caccatcatc tgccattgtt gccttcatcg taccatgctg
    20521 acgaatgatt ttggtcaacg ctctggtatc aattcctgaa atgcctggaa tccccttatg
    20581 ctttaaaaac tcgtccaagg tcatttgctg acgccaattg ctagctatcc tgcttacttc
    20641 agagacaatg acccctttgc aagttggggc aatggactca taatcatcac gattaatacc
    20701 ataattacca acaaggggat aggtaaatac taagagctgc ccgttatagg actggtctgt
    20761 gattgactcc tggtagcctg tcattcctgt attaaagaca atctcgccag tgacatcaat
    20821 atctgcacca aagggctttc cttcaaaaat ggtgccatcc tctaagataa gtaaccgttt
    20881 tgccatttta accccctcta acatgccttt agaccttatc gtttctgcca ttaaggatcg
    20941 cttcgataat ggccatacgg acaaatacac cattagccat ttgagctact attcttgcct
    21001 ttggagcctc tactaaatgg tcagcaatct caacatcgcg attaaccggt gccgggtgca
    21061 taataatcgc agagtccttt aaccgcctgt agcgctcctc agttagacca aactgtctat
    21121 gataatcttc cttggaaaag ctttgactac catcatggcg ctcatgctgc accctaagca
    21181 gcatcaacac atctaattga tcaataatgt gatcaatcgc catgtacctt ccatagctgt
    21241 caaattcaga cgagtaccat tgctcaggac catagaaata aagctctgct ccaagccgct
    21301 ttagaatctg catgtttgat ttagccacac gagaatgtgt caaatcccct gcaatagcaa
    21361 tcttcaggcc atcaaaatga ccaaattctt cataaatagt tagcaaatca agcaagcatt
    21421 gactagggtg ctgacctgat ccatcacctc cattaacgat agaggcagta atcgttggac
    21481 tgtcaataag ctgctgatag taatcatctt ctgggtgacg aatcacgcag atttctgttc
    21541 ctagagcact catggtaaga acagtatcat ataaggtttc ccctttattg acagcacttg
    21601 tatcagcgtt aaaatcaagg actctaagac caagcttgtt ctcagcaacc tcaaaggatt
    21661 tatgggttct tgttgaattt tcaaagaata aattagctgc aaagtgccta ctgttatctt
    21721 taatagctac cttacctgcc ttgtattcag agccacgact aataagtcct aaaacctctt
    21781 catttgttaa atgctccatt gacaccaaat gcttaagcgc aacacgatta tttacaactg
    21841 acatgattta tcccctttta ccaataatga aatgatgata acaattgaca acagctacac
    21901 actagttttc tggaagaagc tgatacaata taatgccaag aagcgttgaa aaagcaacac
    21961 ccgaaatctg aaggccattg atttgaagca tgaggcctcc aataccagaa accagaataa
    22021 cactagcaat caataggttt ttcttgttgt ccatatcaac cttagcttca atcaggattt
    22081 tcaagccact agaggctata accccaaaca gagcaatcga aatccctcca atcactggag
    22141 taggaataga ctgaataagt gctgatacct taccaacaaa gcttaacaaa ccagcaatca
    22201 cagcggcacc tgcaataaca tagactgaga agattttatt gagggccatc acaccaatat
    22261 tttcaccata agatgttacc ggaggcgctc ctaaaaatcc agcaatcacc tgtgcaaggc
    22321 catcacccgt caaggttttt tccaagccag gatccttgaa ataatctctt ttagtcaggc
    22381 tattaagcac catgatatga ccgaaatgct ctgtcatggt gacaaaggca atcggggcca
    22441 tcgttaaaat agcactagga tacaaggtaa tgtcataggt taaaaagggg atagccacag
    22501 ctggaacact gagccattgg gccttagcaa cctgtgtaaa gtcaacaata gactgacccg
    22561 tcaccatacc aacaaggatc gcaaacaaat agccaaccaa taagcccaac aaaataggaa
    22621 tgatggcgac aatcccttta ccataaatgt taaagaaaat aatcgctaat aaggtgacaa
    22681 gaccaatcaa aaggtataac aggttatact ttccatcctt tagcatgaca tcactaactg
    22741 ctgttgaggc caagctaaga ccgatcacca taacaatggg accaaccaca actggaggta
    22801 agatcttatc gatccattca ttgccaatcg ccttcaccac cagtgctaca accagataaa
    22861 ccaggccacc tgtaatcgct ccctgtgcaa ctgcaccaat accatctgtt ttcattagca
    22921 tttgcatggc tgcaatataa gcaaagcttg agcccatata agcgggaatt ttaaatgttg
    22981 ttactgacaa atgcgccaga gtcccaagtc cacttgataa gagggcaact gacggatcaa
    23041 tcccaaccaa aattggaacc aaaacagttg ctccaaacat agcaaataaa tgctggaagg
    23101 acaagccaag caaaatccct gcctttggca cttcttctac atcataaatg acatctttca
    23161 cacaatcacc tctttcttat cccggatcaa caatactaat acgatcttga ccgtcaacct
    23221 caaccacctc aacgacaatc tcttctgtct tgcttgtggg aatattcttt ccaacataat
    23281 cggcccgaat tggtaattca cgatggcctc gatccaccaa aacagctagg ctaacacgtc
    23341 caggacgccc taagctaacc aaattgtcga tagctgcccg aatcgttctg ccggtataaa
    23401 gcacgtcatc tactaagata atatccttgc cggtaatatc taccggcatg ctggtggtgt
    23461 cctcttccac tctcatatca tctctaaagg gcttggtatc tagctctcca actgccaagt
    23521 gcaggctttc tagctgctct aatctttctt gaatacgacg agcaaggtaa acacctcttg
    23581 ttttaatccc tacaagcacc acattgtcta gttgcttgtt gcgctcaata atctcgtacg
    23641 taatccgcgt gatcgcacgc ttcatggtta gctcatcaac aattaccttt gatttcattc
    23701 aaagcctcct caaaaaattc aactaaaaaa atctccctgt taacaaggag attcagcaaa
    23761 acaggcacac agctagacat aactgtgcac ttttttattc agaacatgct ccttgccagc
    23821 ctcacaggac tgttttaaag gaatatttta ttttcattag tatagcaaaa tcacaagcca
    23881 aaaacaagga ttttctaaaa aataattcaa aatatataga gctatcacag caccaaggaa
    23941 aatgctacta aggtcatcag caatcctcca acacaattcc aaaaataggt cttaagacct
    24001 attgtatttg tatcaaaaca atagcacaat aatatcaaac acaaaggaga gcgtttatga
    24061 tgaatgatat aactagaaag attaaccata agcaactgat tcaaatcact accattctag
    24121 gcattattgt taccatcgtt attttgttct atctgcagca gcaccctaat ctttttgcag
    24181 ttggcggtcc ttttcagacc tatcttatgg aacttggtat cctagcaccc tgtttgttta
    24241 tactgcttca aatcattcaa gtggtttacc ctatcattcc tggaggcttg acctgtgttt
    24301 tagggcatgt agtctttggg ccgttttggg gatttcttta taatactcta ggtattttta
    24361 ttggttcgct gcttagcttt atgctcgcta gaaaatatgg tgaacagttt gctaaagcct
    24421 ttgtatcaga tgatacctat aacaaataca ttccttacct caataaaggc aagtactttg
    24481 aacgatttct cataacagcc tttattctcc ctggctttcc agatgatttt ctctgtatgg
    24541 tagctggact aagcagcatg tctatcaaaa catttaccag tattttcttg atatcaaagc
    24601 caattactct ttatatctac acccttcttg cttaccaagg catacaaatc gttggacagg
    24661 tattgcaatc ctaaaaaaag ctagtattaa gctatcaagc ctgattggaa tacagtattc
    24721 caatcaaaaa ggcgctcagc ttggtaccag ctttttatcc ttgtcttagt tgctccaaag
    24781 tcctttggaa gatttctggt ggctcaacag taaagaccag ctcctctcct gtcacagggt
    24841 gggttagtcc caatgtttgc gcatgaagaa actgcccctt gccagccaag gtcttacgag
    24901 gaccgtagag tggatctcct gcaagagggt gaccaatata agccatatga acgcgaattt
    24961 gatgcgttcg acctgtttcc aattgtaatt ccacgaaggt atagtggcca aagcgctcca
    25021 aaaccttaaa aagagtcaag gcttccttgc ccttagcagt tacggtctgt tttttacgat
    25081 ccttttcact gcggccaatc ggagcttcaa ttacacctcg atcctttggt aaattaccat
    25141 gaacaatggc cacatacttt cgtaaggatt tcttagcctt gagctcatca gctagtagct
    25201 ggtgggcctt atcggtcttg gcaaccatta aaagaccaga ggtatcctta tcaattctat
    25261 gcacaattcc tggacgaata acaccattaa tagaagacag gtctttgata tgatagagca
    25321 aggcattgac cagcgtccct gtagaatgcc ccgcagaagg gtgaacaacc attccctgag
    25381 gcttattaat aatggccaat acatcatctt ggtagacaat atctagtggt atatcctgag
    25441 cctgatagtc caagctgctt tcctctggga tatgatagct aatgcagtca cccacctgca
    25501 caatatactt ggccttctta ggtaagccat tgaccaatac ccttttttgc ttgatctgat
    25561 cattagcctg acttcttgat aatggggtca aatcagccaa ggccttatcc aagcgatggc
    25621 ctgattctgt tatcttaatt tccatagtcc tcttctttcc atagacaaat gaccagcagc
    25681 aaaacaccta tcgtcaaata ggaatctgcc acattaaaaa tagcaaaatt gatcacatct
    25741 aaatgaatca tatcaaccac ataggataac ctcaagcggt caataaaatt cccaagacct
    25801 ccagatataa tcagcaataa agagagctgt agccaaaagc tagcctttgg gtgcttcaac
    25861 acataataaa tggcatagcc aaccaccaaa acagttatga ttgtaaagaa ccactgctga
    25921 ttctgtagta tggaaaaagc agctcctcga ttttgaagat aggtcaagct caccaaacct
    25981 ggtataaagg gcttcacctg ccctagctca atatgtgtaa cagtccacca tttacttagc
    26041 tgatccagta tcattaagac aatggcagcc ataataaaac taattctttt caactaatcc
    26101 tattcctttc agcttaaaaa caagagatta ccttgatggc ttcaaaaaag caacaacagc
    26161 cagctgtctc tgtagcgtac tcaaccttaa agcctccaaa aactggtatt ctagtaacct
    26221 tttagtatca ttgatagtca accacacagc agctctagac ttgactttat atcaacaagt
    26281 ctcaccacag cagctcgctt aatccttatc cataccagag ctaagtccca ttgtctatag
    26341 cttgcttttc ttttcgatgt tcaaaataat cctgtaaaat ggtcacaaaa tgtaaagccg
    26401 cagcagatag gttcttatcc ctacgcttga cataaatcat tttatgctcc atatgatcac
    26461 gcaagggaat aaccttgatg ccattaacgc tttgctgatc taaaaatcca gaccctgttg
    26521 caaaggcagc tgtcctttcc aaaatgccat ttaaggttgc cctatctgac acagtgtata
    26581 tgtgaggact cttgcttgtg tcaataaaat tttctgaata ataaagatat tcttcttttt
    26641 cttgagtaaa gcgtaccgct ggcagccctt gcaaatcctc taagaaaagg gctttccttt
    26701 gagccaatgg atggtttttt gataggtaaa tatgggttgt aaaggatagc aattcaacat
    26761 aatccaaagc cagcttatcc attcgctgaa aaagcccctg acggttttgt gcattaagat
    26821 agataattcc aagctcacta tttccctgtg ccacctcatc taaaatttgc atagtcgttg
    26881 actcaaaaac tctaaaaacc ttatgcccag catgcttttg ggaaaatgct gttattaaag
    26941 ctggtaaaaa atcataatgc tgactcgcaa ttgaaaattc atttggctcc aaagccgatt
    27001 gagaaaactc cttttccagc gagtcaaagc acttaacaac ctctaaggcc ttttcataaa
    27061 ataaaagccc ctggctggtt aacacagttc ctgctgttgt cctacgaaag atctgaaagc
    27121 caagctctgt ctccaaatcc ttcactgaaa cagacaaact gggttgactg acaaatagct
    27181 ttgaagcagc ctcacgaaag gtaccattat ttgcaatagc aaccacatat cgtaattgtt
    27241 gaatattcat taatccactt cctaaatcta gtacccttca ttataccata aagccagcca
    27301 atgaaaaata aaggcgtcca tcttaaccat gccaaacgta tctacagata atcatgagat
    27361 agcattgact ttttcaatag tgtcttatca tatttagcta tagaaaacag ccttactata
    27421 agttatactt ttgaaagaag taagccttag atcacagaac atcacactga gattttttat
    27481 gcgcttatcc tgtctgtcca agaactgaga attggctaca tctagctaat aagccatttc
    27541 aggattttac tgtctaggag ttatttatag gcaactatta cagtaagata gtgtcacaat
    27601 acaaaaaagg ctatcccaaa gtacagaaca gccttatacc gtgccctttt aacacattat
    27661 tttgcgattg ggtatacaga aacttgtttc ttatcgcgtc ccttacgctc aaagcgtaca
    27721 acaccttcaa ccttagcaaa aagagtatca tctccgccac gaccaacgtt aacaccagga
    27781 taaatatgtg tgccgcgttg acggtaaagg attgaacctc ctgaaactgt ttgtccatca
    27841 gctgccttag cgccaagacg ttttgcttgt gaatcacgtc cgttagaagt tgaacctcca
    27901 ccttttttgt gggcgaagtg ttgtaggtta gaaagattaa gtttaatcat ttttatttcc
    27961 tctcgttgaa tttaattcat cacaggcttt tgaacatatt ctgataaatg ctctgccaaa
    28021 ttctccaagc caatcacaac agactcaaac agaatttgcc acacctgctc ttgttgctca
    28081 gtaaatccct caggctttgt tacccttagg aatccaccac catcgaccat ttctagtgct
    28141 ggctcaagac ctgtcatctg ttcaactgaa ttaacaagat tgaaggccaa aactgaaacc
    28201 gaagcacaaa ctacatcaaa gccgtactca ccgcttccag catgtcctgt gataagcatc
    28261 tcagtccagc cagctgcgtc ttttgttaac cgtactttaa tcatgtcaaa ctagaattat
    28321 gccttgatag cgttaatcac aactttagtg taaggctgac gatgaccttg cttacggtgg
    28381 ctaccttttt taggcttgta cttaaaggtt acaaccttct tttgttttcc ttgcttttca
    28441 acagttccaa cgacagtagc tccctcaaca actggagtac caacgacagt cttatcacca
    28501 cctacgagaa caacctcgtt aaaagtgatt tctgcgccag cttcagcgtc aattttctca
    28561 acgtagattg cttgacctac ttcaacttta acctgttttc caccagtttt gatgattgca
    28621 tatgtgctca tgatgcacct cctataagat ttttgatgag gtttccctct gtgaagactc
    28681 gcctagaatc gtgagagcca atctacttga aaacgatttt cgtgcggttg cacaggacgt
    28741 gcacttagtc aacgttacaa ttttaacatc aaatttgatt tttatcaaga aaaatatgct
    28801 tttatcttcc taaaatctta agctatacat aatcacagct atgtaaaggc tagcaatgct
    28861 ttaccatttt aggttaacca gggcattcat ttctttataa gcaatagctg ctttttcttg
    28921 cgtttcggga tcaatcttat cataatatct gccgcctttg ataaagtcct ccaaaaccat
    28981 ggtacgatag ctatatagct catagccttc actaccataa aggcccttag gcttagctaa
    29041 aaccattgtc gggtgagcct ttactgtttt tatttttgtt ttttgcccct tcttctcaaa
    29101 ggtaaggtcc attagcacgc cgcgctctgt ccaaatatca tcaacagtct ctaggcgttg
    29161 attggaaatg aaattaccca ttgaatagat aataaatttc ttttccttgt ccttaacaat
    29221 cgtctctgcc ggctctacga cgtgggggtg acctcctaag acaacatcag caccccagtc
    29281 aatcattttt cgataaagag ttttttgctc agctgttggc tctaaagcat actctgtgcc
    29341 catctgcggc ataacaatgg taatatcggc ctctttttca gcacgcaaga tgtctttttg
    29401 tatcttttcc tcattaaggt cagacaggtg cttgtcatac tcctcctgac tgagtgtcgc
    29461 ctccattcca ttatagccat atgaatagcc caatattgca atcttaatcc cattaacctt
    29521 tttaatgaga atgttctcct tagagcgatc ctgctcataa ataccaatgc tgtctatccc
    29581 catatcagca aaaacacgct tggtattgag agctccttct aatcttgagt ccaaaatatg
    29641 gttatgggcc aaatcaacca catcatagcc agtatgctta agcgcagcag caatagcctc
    29701 tggcgcatta aacaaaggat agccagctag aggatagtct ggactgatcg ttccctcata
    29761 gtctccaatg gccaaatcag cctgactaat ccaatccttc acatactcaa aatagggatt
    29821 aaaatcatag ctaccatcag cctttttagc actcatatag agaatatcat gaatcaaaat
    29881 atcaccattt gcgacaacac gcgctgtttg tgtcttttga ggtgtcttgc ttttcgtttg
    29941 tgtgcctttt tttgacatgc ctaataaatc aaaggccaac ccaaaaacaa gtatcaccac
    30001 aatcaaggta agcactgaaa gcatggtctt tttatactga aaatctttta gcaagcgtca
    30061 aacctccttt tttcctatta taccatgttg acacgacttt ttaataacaa atcccaaaga
    30121 aaaggctatg cccatttaag aagaatgcct tagacagcag catagactcg tattagctag
    30181 tcaaaaaact agattgctcc tctttggttg atgtcatata ctttgagcct aaatagcttt
    30241 caacaaagtc taatagttga ataatgtcat gcaaaatatg gtataatgaa acaaaatcaa
    30301 actagtcagg atagtcacat gaagcataac tctttcagcc gctcactatt actccccctt
    30361 ctcatctgtt ccttgtctgc ttgctcttct catacagaga aaaaagacca taccaaagac
    30421 gctactgcta tcaccgatac ccgaaaagca gagcatcagg acatcagggc aaatatggaa
    30481 aaggtcaagc tcgctaccgc tagcaccgac ttcaaaggtg gctcaagcct tgaggagcta
    30541 atcactattt ttggacagcc tagtcagcac gaagaaaaag cagctggtag tgttactctt
    30601 gactcctaca catggcagtt tgaccatgtc acggttaata ttaacctcta tgaaaacagc
    30661 agcattgtta aaactattgc taactttgct tttattagag acctgacctt atccttaaag
    30721 gactacaaca gcttgaaaaa gggcatgacc tatgatgagg tcaagcagct attgactgag
    30781 cctgataatt acagtcaagc caattccagt gaaaaagaaa ccattcaagc catttggatt
    30841 agtggcttaa aagctcagac acagggtgcc aatatagcac taacctttga aaacaaccag
    30901 ttgacagaaa tgtcacaggt tggtcttgaa gactagtttg tggataaccc caatcatatt
    30961 aatgatagaa aaaagcttga tatttaataa gatcaagctc aaacgataga ccaagtagct
    31021 gatgatcttg acagtaatgt gtaacaagct gagatactac tcactaggca gtatttacta
    31081 gcagccactg aatttccttt atgatgacag gcaaccacct tttttgtggt gacctatcaa
    31141 tagcaccata agctctcttt tgtcacatac cttgcttaac attattttac caggtatgtg
    31201 atgagctttt taggttgtct gatagtataa catctaaccc ctagttgatg atgtagataa
    31261 ggcaagagct gctaaggata gcaccataaa taagatccaa catagggtca tattatatag
    31321 tgccaagaac gaaaagataa agacacctac agggagcgat aaagagaaca gaagacctaa
    31381 aaagttattg ctttgggcta gcatatctga tgggagattt tccattaaaa gggcgtccag
    31441 cttgggtgtg gcttttccca taatataagc tgcaaaggct aagcataaaa cccctatgat
    31501 ggcaggtaat tgcagagcat tagagactcc taccagcaaa aatgctatgc cctgagtctg
    31561 tactagcttt gatattgaaa gccttgaaaa gtaatccttt ggtgttagat ttcccaacat
    31621 cgctccgata atcgtaacgg catcaacaat aactaaagac tgcccataat gaaaatgaaa
    31681 tagctgatga tccatcaaat aaaaatgata aatgctatta attgctcctc caatagcgtt
    31741 taaggtcaag atggataaga gtaacatcac aaaagagata tgatcaatct ttttaaaggt
    31801 ctctgtcatc cttgtataca tcaccttaaa ttgcttcatt aatgaaacac ctgcttcaga
    31861 agcttcaacg acatcatgcc ttagcttttg tcgattttta agaagcacaa cagatgacaa
    31921 taaaaaggaa atagcattta tcaaagcaac aaaggcataa ttgttgcctg atgtcgttag
    31981 cagccaaact cctaaagctt gtcctgcaat actagagagg tagccgataa attgagcaaa
    32041 agaataggcc tcatagagct tttctgattc aatatttttc tgcattatcg ggagacgtaa
    32101 gccatttttg taatcactta gaatatcaga aaccacattc aaaaagccca caaaggcaaa
    32161 taccaagaac gtctgatttg tcatcaacaa ggctacaagc gtaaataaaa gagattgtat
    32221 aaaaccaata acaataagat ttcttgtttt cctttttgtc ttatctgctt tgacgccaat
    32281 ccaaaaggta aacaccatag gaatgatggt gatgatattg gctataaaaa cagcaatatg
    32341 agaataaggt agcgtggttg cataaataat aaaaacaata ttgtaaatat aagagcctaa
    32401 agcacttaaa aagtttgaaa ctgtcagtgt tctaaaaacg acatttttaa tcaatcccct
    32461 catttactta cctgttgacg tcctttctta tgtcacctta ctttacttga ttgaatatac
    32521 ttacagcata tctaaattcg tactgtagtt ttatatggtg ttctgacatg attttgctac
    32581 taattagtaa ttcacaagcc ttttctaagt ataaagtatc gtttgttagt ctaaatactt
    32641 gtaaaagtgt catggctatc cccagcattc cgttccatag accactaaac tgagcaaatt
    32701 caactaataa cgactccgat aaattcttaa tatctttaat atatttatcg gagttaacgt
    32761 aaataagcaa ttgaacgatc ccagcagtcc catttgataa gtatggagat acagaatttt
    32821 ctgatattaa tacaccccga tttccatcgc tatcttcaac taagctttct agaataaaat
    32881 caattccttt ctcaataatt tcgttatcat aagaaattga agacagatag aacaatactc
    32941 cagctaaacc atttaaccct aaattaactt c
//
LOCUS       DARYVE010000019        32698 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYVE010000019 DARYVE010000000
VERSION     DARYVE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32698
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(555..1697)
                     /locus_tag="TVW25_000815"
     CDS             complement(555..1697)
                     /locus_tag="TVW25_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378467.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(1694..2557)
                     /locus_tag="TVW25_000816"
     CDS             complement(1694..2557)
                     /locus_tag="TVW25_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378468.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(2568..2894)
                     /locus_tag="TVW25_000817"
     CDS             complement(2568..2894)
                     /locus_tag="TVW25_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1378469.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(3498..3662)
                     /locus_tag="TVW25_000818"
     CDS             complement(3498..3662)
                     /locus_tag="TVW25_000818"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378470.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(3901..4797)
                     /gene="era"
                     /locus_tag="TVW25_000819"
     CDS             complement(3901..4797)
                     /gene="era"
                     /locus_tag="TVW25_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1378471.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(4933..5334)
                     /locus_tag="TVW25_000820"
     CDS             complement(4933..5334)
                     /locus_tag="TVW25_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1378472.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(5315..5812)
                     /gene="ybeY"
                     /locus_tag="TVW25_000821"
     CDS             complement(5315..5812)
                     /gene="ybeY"
                     /locus_tag="TVW25_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1378473.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(6161..6787)
                     /locus_tag="TVW25_000822"
     CDS             complement(6161..6787)
                     /locus_tag="TVW25_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378474.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(6842..7417)
                     /locus_tag="TVW25_000823"
     CDS             complement(6842..7417)
                     /locus_tag="TVW25_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1378475.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQAPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(7464..8564)
                     /locus_tag="TVW25_000824"
     CDS             complement(7464..8564)
                     /locus_tag="TVW25_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1378476.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(8667..8882)
                     /locus_tag="TVW25_000825"
     CDS             complement(8667..8882)
                     /locus_tag="TVW25_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1378477.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(8879..9388)
                     /gene="msrA"
                     /locus_tag="TVW25_000826"
     CDS             complement(8879..9388)
                     /gene="msrA"
                     /locus_tag="TVW25_000826"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1378478.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(9726..10583)
                     /gene="cvfB"
                     /locus_tag="TVW25_000827"
     CDS             complement(9726..10583)
                     /gene="cvfB"
                     /locus_tag="TVW25_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1378479.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(10717..11274)
                     /gene="frr"
                     /locus_tag="TVW25_000828"
     CDS             complement(10717..11274)
                     /gene="frr"
                     /locus_tag="TVW25_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1378480.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(11311..12039)
                     /locus_tag="TVW25_000829"
     CDS             complement(11311..12039)
                     /locus_tag="TVW25_000829"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1378481.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(12338..13018)
                     /locus_tag="TVW25_000830"
     CDS             complement(12338..13018)
                     /locus_tag="TVW25_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378482.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(13005..13793)
                     /locus_tag="TVW25_000831"
     CDS             complement(13005..13793)
                     /locus_tag="TVW25_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378483.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(13781..14587)
                     /locus_tag="TVW25_000832"
     CDS             complement(13781..14587)
                     /locus_tag="TVW25_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378484.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(14572..15513)
                     /locus_tag="TVW25_000833"
     CDS             complement(14572..15513)
                     /locus_tag="TVW25_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1378485.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(15591..17213)
                     /gene="nikA"
                     /locus_tag="TVW25_000834"
     CDS             complement(15591..17213)
                     /gene="nikA"
                     /locus_tag="TVW25_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1378486.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            17715..19355
                     /locus_tag="TVW25_000835"
     CDS             17715..19355
                     /locus_tag="TVW25_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1378487.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGKKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(19599..20288)
                     /gene="rplA"
                     /locus_tag="TVW25_000836"
     CDS             complement(19599..20288)
                     /gene="rplA"
                     /locus_tag="TVW25_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1378488.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(20394..20819)
                     /gene="rplK"
                     /locus_tag="TVW25_000837"
     CDS             complement(20394..20819)
                     /gene="rplK"
                     /locus_tag="TVW25_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1378489.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            21055..21852
                     /locus_tag="TVW25_000838"
     CDS             21055..21852
                     /locus_tag="TVW25_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1378490.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            22007..22357
                     /locus_tag="TVW25_000839"
     CDS             22007..22357
                     /locus_tag="TVW25_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1378491.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(22686..23078)
                     /locus_tag="TVW25_000840"
     CDS             complement(22686..23078)
                     /locus_tag="TVW25_000840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378492.1"
                     /translation="MSPTERELKKEKEVLRNFIATIKLSYSEANEMEAKVYGADSFSK
                     LRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFPEGHSRNIMKKYRLEFLDRLMGIQY
                     DVGLNKDRALDDLSERIIMTRKKLWYIQ"
     gene            complement(23516..25915)
                     /locus_tag="TVW25_000841"
     CDS             complement(23516..25915)
                     /locus_tag="TVW25_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1378493.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            26035..26208
                     /locus_tag="TVW25_000842"
     CDS             26035..26208
                     /locus_tag="TVW25_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378494.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            26295..27101
                     /locus_tag="TVW25_000843"
     CDS             26295..27101
                     /locus_tag="TVW25_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1378495.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(27257..28090)
                     /locus_tag="TVW25_000844"
     CDS             complement(27257..28090)
                     /locus_tag="TVW25_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1378496.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(28091..28816)
                     /locus_tag="TVW25_000845"
     CDS             complement(28091..28816)
                     /locus_tag="TVW25_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1378497.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            complement(28876..29808)
                     /locus_tag="TVW25_000846"
     CDS             complement(28876..29808)
                     /locus_tag="TVW25_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1378498.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            29954..30601
                     /locus_tag="TVW25_000847"
     CDS             29954..30601
                     /locus_tag="TVW25_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1378499.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            complement(30657..31358)
                     /locus_tag="TVW25_000848"
     CDS             complement(30657..31358)
                     /locus_tag="TVW25_000848"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1378500.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(31382..31630)
                     /locus_tag="TVW25_000849"
     CDS             complement(31382..31630)
                     /locus_tag="TVW25_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378501.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            complement(31630..32184)
                     /locus_tag="TVW25_000850"
     CDS             complement(31630..32184)
                     /locus_tag="TVW25_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1378502.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            complement(32215..>32698)
                     /gene="glmU"
                     /locus_tag="TVW25_000851"
     CDS             complement(32215..>32698)
                     /gene="glmU"
                     /locus_tag="TVW25_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1378503.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQAK
                     "
BASE COUNT        10036 a         7587 c         5941 g         9134 t
ORIGIN      
        1 tttttaaaat catcaataac ctatctaaat tttctaaaca atgccatata aaaagagctg
       61 gagtcaccaa gctctaattg atttttacat gatgctctat aacaatatcg tttaaagatc
      121 attctttttt actagtatgt tgatcacatt ttctaaaagc cagaaagaga cttgaatacc
      181 gagtcccttt tctttttatc tataaacagc cttaaagaag cccagacagg ctgcggtaat
      241 tttcttaaca tgagcttcta ctatttctct tgttaagccc tgctcacttg atgattcgtt
      301 atttttacca cctgaagact ctcctctaca taggctactt tgtcatctag ttcctgcttc
      361 ttaacgatat atcatcgtct caattgatgc cacttccctt atcatcttag aaaaaagcta
      421 atttctatac ctttaggtgt tctagatcac aaaatagctt tctcaatcct atctaccttg
      481 caagaattca ttgaatgccc ttaacttttg cagtaacgac aataaaaata gtttagataa
      541 cgatgctatt gatgttactg acttaccctc tttattgata agtatgctaa atataagcaa
      601 agaaatgcaa aagctaatct aatcatgaca ataactaatc catcaaccca aaaactgcca
      661 aaaaagccgt cataagcaag cttaagcatt atgtttggtg tactcgcagt tgatacagat
      721 aaaatactca acaccttatg aggtattcct gcttggaaaa tatccataag aaaacttggt
      781 acaaaaacac tagccgcaga caaggcaaaa cctgtcaatg gagacttaac cttacttgaa
      841 ataaggatag tgatagccgt aatcaggata agcccaataa actgataggt gactagattg
      901 ataaatgttc ccaaaagagt cattttttct ggaaaagcca ttatattcac attgctgtta
      961 atccaataca gattgagttg aacactcgtg tcccaaccac ttaatccaaa ataccaaaca
     1021 aagaccgcta atattatggc gtaaaaagta acaaacactg aggtgcttat caagtaacta
     1081 cttattatct tggctatcgt aagtttatta cgaccatacc tagttgtcaa taaaatagga
     1141 ttcatatttt tagcagtatc accggaaaaa acaggagcga tgaagtaaac agacaaaaga
     1201 agaagaagga tataagcact atttatgacc agaaaaagct gattccaggg tgcaaaatta
     1261 cccaacttca gctctttaaa gggaagataa gagccaagag ccgtttgaga ttttggggtg
     1321 atcttactga aatcaatagt ctcttctttt ttcaaattaa aataataatc tctaaatttt
     1381 ggatcaaaat ggctagttac atagtagcca tacacattga agacaggatt ttttgagctg
     1441 ccacctagag tataatcttt gattgttcta attaataact cattggacaa ttgaccggta
     1501 tgttcttccg caaatcgctt gtttatctca acagcatctc ttccatgaat tttatctatc
     1561 gaagaaccac tgatttgtcc attaaaaaag ttgatataaa ataacccaaa gattgctaat
     1621 aagctaacaa taaacattcc caaaactgat ttggttcgga tcagtttttt taattcaaat
     1681 ggtaagagag ctttcataac acctgttcct ctctaaagtg ataaatgtat aagtcttcta
     1741 aggttggtga cactagttga gccaactgat ttggtttctc atcactaacc acacgaaaaa
     1801 cacgactaga tgaaactagt ttctcattga ctacagcata ctgaccatgc cttggtaacg
     1861 gcgaaccatc agagacagaa aactcccaga ccttgccaaa gatggttttc aacaattctt
     1921 gactactact cttatggata aattgaccat tttttaaaat gataatctcc ttagcaatag
     1981 cctcaacatc agagacaata tgagttgata agataataat tttgttggcc gacaattcgc
     2041 taataatatt gcgaaacttc accctttctt ttgggtctaa tccaactgtc ggctcatcta
     2101 aaatcaagat tttagggtca ttgagtaagg cctgggcaat accgagacgt tgcttcatac
     2161 caccagaata agaggcaatc cgcttcagac ggacatcata tagatccaca agttttaaca
     2221 attcatccgt ttcttgcttg gctttatgtt taggtattcc ttttaaggct gccatataaa
     2281 gaagaaagtc tcgaccagaa aaacgaccat aataactaaa ctgttgaggc aaaaaaccaa
     2341 tatgctgata aaattcctct gattgaggtt tgtgatccag taaaatctct ccttcatcag
     2401 gagtcgtaaa atgactaatg agattgagca aggtcgtttt ccccgtccca ttagccccta
     2461 aaagtccgta aaggcctggg gtgaattgag tagtaatcct tcgcaaaata tttttcgatc
     2521 cgtagctctt actcaattga tttaattcta ataacataga accctcctta aatgagtcta
     2581 ctgagcacct gtaactcagt actcagtaga cttctcctgt acgaaatcct gctgtctgta
     2641 acctttatta ttctcgtagc ataatcaaat ccagagattt tcgattcatt aatgaaatat
     2701 tgacgatgac acctttttaa tttcccagca ctttctccct caatctgtct cagtgacgta
     2761 gctgccccaa attccccttt tagggtaaca aatactactg tgtgaggctt agatgaatgt
     2821 gttgtcacat cataggtttc agagattggt aatttaacaa ctgacctatt cttatataaa
     2881 ataacatatt tcattgacgt cctccttctc tatttatatc ttaatacaag tacaagcatt
     2941 gagacggtaa agtctcaaat ggtatctatc atatcctgaa tggtatcaca gtagctgttt
     3001 aagatgtcat agaggcattt gagaaatgta acctgttttc ctttcgtttt ttgatcatat
     3061 gatattgtat tagttcggag aaccatggta atcattcaaa tcttacataa acctctcttg
     3121 ggatatggta ttagcgtcta tattaattac tacttcaaca gacacctttt taaagctgct
     3181 aaaattgtca gtggcaaaca aataggctat aggtataaat ctcacactta ttttatcata
     3241 aaatcattct ttttatcatc taatcaaatg tacaagcact ttaaagttat tctcatgact
     3301 ctattattct tattggaagc catattaatt acgacgacat tttcagaaat cattatcgtg
     3361 tgtttggtat catcgacaca accgctaata aatcgtttaa atgtatccaa aaccaaattc
     3421 atgattacct gttcaaagaa taaccagagg gcttactgat tgctttaaca aatatttcta
     3481 gtcttctcat tttgtactca tataaactca tctactctat taaaaattgc tgtgaacaga
     3541 aaaaccttct caacctgttt cagttttata gccgtagtta gtttaaagtg aaaccaccct
     3601 gcattttcta tacctaaatc caattgactt gctttttcag catcaacagt catgctatcc
     3661 ataagataac acaccacgat gtgttgtgat tattgttctt ctatatttag ccttacctcc
     3721 tgaaaacaaa aaaagagaac accttttaaa tgttctcata taagcaatct tatatattaa
     3781 atgaggattc gatctaatga caagacagcc ttattgctac caataatgca gcttaccaaa
     3841 caagggcaat cagtataagg gttgctaacc agctctgctg acatagcctg ctttgagcga
     3901 tcaatactcc ttctgattat agccaaagtc agctaaatca agctttttgt cacgccagtt
     3961 tttcttaacc ttgacccagg tctccagata gaccttatcg cctagcatta gctcaatatc
     4021 acgccttgcc agcttaccga tttttttgag catggcgcct tgttttccaa taataatgcc
     4081 tttttggctg tcacgctcta ccatgatggt aactcggata tgcaccttgt cagtcacctc
     4141 atcacgcttc atcgaatcga ccacaacagc aactgaatga ggcacctcct gctgtgtcaa
     4201 gtgaagcacc ttttcacgaa ccatctcaga aacaagaaag cgctctgggt gatcagtgat
     4261 ttgatcctct gggaaatact ggaagccctc ttcaaggtta tcctttaaga gctgaacgag
     4321 cgtttcgacg ttgtttcctt gaagtgctga aataggaaca atttccttaa agtccatctg
     4381 actacggaaa tcatcaatct gctccaataa ttggtctggg tgaaccttgt caattttgtt
     4441 gatcaccaaa ataaccggaa tacgagcagc cttgaggcgt tcgataatca tatcatcacc
     4501 cttaccacgc ttttcatcag caggcaccat aaaaagaacc gtctcaacct cacgcagggt
     4561 actataggct gattccacca taaaatcacc taaggctgtc ttaggcttat gaatgcctgg
     4621 cgtgtcaata aaaacaattt gctctgtctc tgtggtatag attcccataa ttttattacg
     4681 ggttgtctgc gccttatcgc tcataacggc gattttttgt cccatgacat gattcaaaaa
     4741 cgttgatttg ccgacatttg gtcggccaag aatggcaaca aagcctgatt taaacataag
     4801 ctactaaggg cctaaaggat cagtcaaggt aagaatcaag cagcaggcta ttcacctgat
     4861 tgctttccta aagcttatac tcctttcctg cgctgcacta tcgcacagga tagcccattt
     4921 cctttcattt ttttaatggc ataacattcg ccaaattttg ggaacaaaga taatcagccc
     4981 cgtcaaaaca gcatagcctg aaatgaccag gacagcacct gcagccatat ccttggcatg
     5041 cttagccagc atggagaaat ggtaatcact tgccaagtca accacatttt caatagctga
     5101 attgacaatc tctaaggtaa tcaccaaaaa aatagccagc aataaaaaca gccattctat
     5161 agcagaaata ccaaaaacaa tcccagccaa agaggctaac agggctgaca aaagatgact
     5221 tcttaggtta cgctcctcct taaaggctgt cagaacccct gtcaaagcaa attctaagct
     5281 ggcaattact gttctgtttt tccatttgcg tttattattg tcttgtgagg ccataagcag
     5341 tcaaaatctc ttcctgtaac gtaaacatct ctttttcttc ctcaggagtg taatgatcat
     5401 aaccattaat atgcaaaaaa ccatgaacag ccaagaagcc catctcacgc tcaaaggaat
     5461 gcccataggc ttctgcctgc tcatgggctt tgtcaacaga aataaacagc tccccaatat
     5521 aagcatcaaa ctcctgtatc atacctgcca agtcaggatc aagctccaaa tcctcttggc
     5581 taaaggcgat cggaagctct ggcttgtact ccagagaaat cacatcagtc ggacgatcag
     5641 tatcacgata ttcaagattc aaggcgtggc ttctatcatt ggtcacaaag gtaaccgcca
     5701 tttccttgtc ctctttacca attgttttgg cagcaaaatt gagcaaatca atggtttgct
     5761 ccatcatctc ttgagaaacc tgcttagttt catcaatcat ctctatatac atcattatat
     5821 gaagaggtcc tagcaagaca ggtccaaaca aacaccacac tgctaggtca aaaagcttga
     5881 tacctcttat cctttcaaca tcatttcagt actttctttc cattatacca caagaaaaaa
     5941 gaaaaagcag gcattagtct agcctgctcc aaaagaagcc ggaataatga caagatcgtt
     6001 gataccccag cagctgctgt ttctggaata cccagagcct gctgcgcaga atacagtcct
     6061 cttagatagc tgggactcct aggattacaa tagtagataa gcctttagac cacttccatc
     6121 gcctaaaaac taatcctaaa cggctttccc ttagatacca ctagctgctc tcaaagctat
     6181 tgtggaggta acgatctggc ttattggctg acgccagtga tttctgcttg tcataatctt
     6241 ctttggttaa ataatagtgc agcactgtca caaaacggtt ggaatcaagg tgatcacgct
     6301 tagcatatgg ctcttcatgt gaaaagcaca tgccgctttt agccataaca cgtcccaaag
     6361 ccggattggc tttatcatgc ttagcaatca cacaattcat gcctaaagct tcaaaacaca
     6421 agaccagtac agccttgaca gcctctgtcg catagcctct tccccagtga tgcttatgaa
     6481 gacaatagcc aatctcagct ctacctaaat ccagctgtat atgatgaaga tcaagcgtcc
     6541 caataaagtc tcctgtttcc tttaacacaa tcccccaccg tccaagtgga ctagccagat
     6601 agacagaagc aatgacttga cgggtctcct caattgtctg attggctgga aagctatacc
     6661 tgacagtctc ttcatcagaa gcataatcaa acatggcttt ggcatcatcc aaggtcactg
     6721 gacgcaggca tagacgctct gtctcaagat acctatgctc tgctagtttt tcaaaaaagc
     6781 ttgccactac tactctccct ttcctaaaaa tctaactcac ctaacagcat gactgcctgc
     6841 cctagccgcg taaaatctgc ctcaccttat cctttaaaac aggaaccagc tcctcttcaa
     6901 accaagcatt tttagccaac caaagctgat ttctaggaga tgggtgaaca aggggaaaat
     6961 aatccggaag atagtcctca aaatgctgca ccgtttcggt aagattgcgt ctacaacctt
     7021 caccaaggta atattgctgg gcatactgtc cgaccagcac caccaattca acctgaggca
     7081 tcaaggccat taacggacca tgccacttgg cagcaaagcc ctttcgcggt ggtaaatcac
     7141 ctgattttcc cttaccggga taataaaaat ccataggaag aacgccaaac aagcccgact
     7201 gataaaaggt cctgtcatca acacccagcc aagctctcaa gcgaactccg ctacgatcat
     7261 tccagtacag acgcgtctcc tgagctacaa taccaggcgc ctgaccaaca atgactatcc
     7321 gagcggtctg aggagctgca taaagtggtt cgataccttt tttggtatag tcacgattgg
     7381 caggatcagc cataatcgct tgcaatagct ctgtcatgat accctcactt tcataaaagg
     7441 ctcttcaggt gaagagctct tttttacgat ttgtcttctt taggcagctc tccaatgacc
     7501 tcataggttg ttaagcctga cgtagactga cccgtctctg ttttaggccg atctggagcc
     7561 ttagtctgat gttgcagctg attagggctg ctttttaatg actctgcttt tgaacctaca
     7621 gtttcatagg ccttaataat ctcagcaaca acagggtgac gcaccacgtc cttggctgaa
     7681 aaatgcacaa aatcaatctg cttgatggcc tgcaattttt gagctgcatc aatcaagcct
     7741 gatgtgatat gacgcggcaa atcaatctga ctaatgtccc cattaacaat cattttagac
     7801 tgaaaaccaa gtctggttaa aaacatcttc atctgcatga tggtcgtgtt ttgcgcctca
     7861 tctaaaatca caaaggcatc atctaaggtc cgaccacgca tataagccaa gggagcaatc
     7921 tcaataatat cacgctccat taaccgagta gtctgctctt taccaagaat ctgataaagg
     7981 gcatcgtaga ctggtctaag gtaaggatca accttttcct tcaaatcccc tggtaaaaag
     8041 cctaagcttt ctcctgcttc aacagctggg cgtgtgagaa tgatccgctt aacctgacca
     8101 cgctttaaag cagtaactgc tagcgtaact gctaaaaagg tctttcctgt tccagccgga
     8161 ccaataccaa ataccacatc atgatgcttg atactatcaa cataggcctt ttgccctagc
     8221 gtcttaacac gaattggctt gctataaaag tccttgataa tctcttcctc ataaagagca
     8281 acaaattgat caagcctatc tgaatccgcc atagacagcg cagtcaccac atcagaggta
     8341 ttgataacca tgccacgccc caccaaaact aaaagggctt gtatcgtcaa acgcgctagc
     8401 tcaacagccc gctcatcatc accaataatc tgaactcgct cagttctagc atgaatcaca
     8461 acattgaggt gagattctat catcttcaaa tggcgctcat tgctaccaaa aagagctaac
     8521 agatcatctg ggtgattcaa gctaatgtca gtcgaataat gcaaatttgt cttccttttc
     8581 catctataag taactctatt ataacaaatt ttgctataaa tcgggaataa gacccagctt
     8641 taaagcctaa aagagctagc ctatggctag tggctaaggt aatcctccca aatctggtca
     8701 aactgcccca gattgaatga aaagctcgct tcctcttcaa ggtaacgact gatggtctca
     8761 aaatcatctg tatgctttgg aaaggtcggg tcctcaaaaa ccaaatcagc taataaagca
     8821 gcaggcttat tagatgtcga gttgcgctga gccatcagcc aagtgtaaaa cgcctttctc
     8881 attgccaatg ctcctccaaa aattgatgac gaatagcact actttgtgca taacgctctg
     8941 gattcttttg ataaaagccc tgatgatagt cctctgctag ataaaaaggc tctgccggtt
     9001 caatgcttgt cacaatgggc tggtcaaagc gccctgaggc ctgcagggtc tgcttggacc
     9061 gctctgcaat ttcccgctgc cgctcatcag tatagtaaat caccggccga tagttgtctc
     9121 ctctatcctc aaattgccca aaggcatcgg tcgggtctgt ctgagcccag taaagctcta
     9181 ccaaatctga atagctgatc agactcggat caaagataat ctcaacagct tcagtatggc
     9241 ctgtcgtctt tgagcaaacc tgctcatagc ttggattgtg aacatgccct cctgtgtagc
     9301 cacttctcac tgataaaata cctgcctgct cctcaaaagg ctgcaccata caccaaaaac
     9361 agcctcctgc aaaaattgct ctttccatac ctaatctcca ctttctttgt ccttacatta
     9421 gtgattttca ttgtaacaaa aaaccttgcc agaggcaaag cttaatataa aacaagtcac
     9481 agactcaaag taacaagact cctcagccca actagtgcct agcactaagc agtactgtca
     9541 agcagccact actagatcaa gagggccaca cagagctttt tcgacaacaa aaatgattgg
     9601 cgctttaaaa caggctatca gctaagctcc acactcaaaa taaggaagct agctatactg
     9661 ataaaggata agtcttagca acaccgatcc agcttatgat tataggctaa gagacagaca
     9721 gctccctatg atatcagctc agttcctgtc acgtcctgct tgatcttgtt agccttcatc
     9781 aaaccaccta aggccttttt aaattgaccc ttggaaatcc caaaggttgc cttgatatcc
     9841 tctgggcttg acttatcatt aagagtcatg tagccaccat tagacttgag ataggtcaga
     9901 atcatctggg catcgttttc cagcatttca aaggaacgcg gctttagcga aaggttgagg
     9961 gtacggtcac gttctctaaa gccaatcacc cgagcggtca aaacctgccc caaacgaggc
    10021 tccgtataac gctcgctagg gtggataaag cccagcatat tattttctgg caggtaaaca
    10081 aaggtccctg atagcttcaa gcgatagaca atagcaggca ggctttgatt ttgcatgtta
    10141 tcataggctg gactagcaag cctttgaaat atctctggct cagctggcaa accccagata
    10201 cgatcttttt tgtcaaccac aagcttaaga taaagcctgt ctcctttttt aggccaaaga
    10261 tcctttagct ccggcaaaac atctaaggaa accacaatct ccttatctgg aataccagta
    10321 tcaacaaaca ccccaagatc acgacggaca gtggtcacct cgccccagcc ataatgatca
    10381 cgccttgcgt caataggctt cgtggtcaag cgtagtcttt gcttcatatc tgtatagaca
    10441 aagcccttaa ccatatctcc taatctatga ctgccttcct ccttagctag agcaaagctc
    10501 agcccctcct tttggacaag ataaaactga ctattttctt cttttactaa gccagtgata
    10561 actgttgcta ataaatgatt catatctttt tgttctttct tttaaaaaat agggacaagt
    10621 ccaaagcagc tgctttttag ccttgtcacc tatcctgtta tgcctgatgt gtattaggtt
    10681 acgcagctga tctagcttaa tgatcagata agccgcttaa actgaaagta attccttttc
    10741 tttgtcagca gtcattcggt caatctcttt gacagcctca tctgttgctt tttgaatatc
    10801 cttttccaag gcttttaact catcttcagt gatttcctta gccttctcct gctttttagc
    10861 ctcgtccata gcatcacgac gaatattgcg aatcgaaacc ttcgcagtct caccaacctt
    10921 tttcacttcc ttggctaatt ccttacgtgt ttcttctgta agcgctggaa taaccaagcg
    10981 gatgacagag ccatcgttag ctggtgtaat gcccaaatca gaagcattca aggcacgctc
    11041 aatatccttg attgatgatt tgtcaaatgg tgaaatcaaa agcacacgcg cctctggtac
    11101 tgtaatagaa gccaattggt tcaacggcgt tggtgcacca taataatcca cctgaatacg
    11161 atccaaaagg ctagcattag cacgacctgc acgaatgctt gcatactcgc gtgctagtga
    11221 gtgatgtgac tgtgtaaaac gttctttcgc agtttcaata attgcatttg ccatgattgt
    11281 ttttctcctt aatcctttag ctctaaaatc ctaatcgcag gccttatttg ataccgttgt
    11341 gccaatatgc tctccaaaga ccacacgctt gatatttcct gcttcattca tattaaagac
    11401 aaccaaatca atatcattat ccattgacaa ggttgaagct gtcgcgtcca taatcttgag
    11461 accgcgcttg ataacctccc catgagtcaa ttcatcaaac ttaacagcgt ttgcgtcctt
    11521 tcttgggtca gcattgtaga caccatcaac accattttta gccatcaaga tagcatctgc
    11581 ctcaatctca gcagcacgta aggccgctgt cgtatctgtt gaaaaataag gtgacccaat
    11641 accagcaccg aaaacaacaa tgcgcccctt ttccagatga cgaagcgcac gacctcgaat
    11701 ataaggctct gcaacgtttt gcatgggaat agctgtctgc acacgagtat caacgccata
    11761 atgctgaagg ctatcagcca ttactagagc attcataacg gttccaagca tgcctgtgta
    11821 atcagcctgc acacgatcca taccagcctc tgcagcaggc tcaccgcgcc agagattacc
    11881 accaccaata acaagagcaa tttcaacacc tgaattgtga acttctgcga tctctttagc
    11941 aatcgactga accgttgtta tgtcaatgcc aacaccctta tcaccagcca aggcctcgcc
    12001 agacaatttg attaaaatac gttgatattt aggtttcact atttatgatc tccttatttt
    12061 gtccctacca ttctaccaca aaacaaaaaa atttaataga ccaatgcaag agaggaaagc
    12121 gaaatttttg acgatccttt tatcaagatc cctttgagca gcaaaaaaga tgagtcatta
    12181 taaaaagagc attatcgtat ccgaatagca cagttataac ctattaatac gacaaaaacc
    12241 agaacaacta tgacaaaaaa cgccgtaaaa aagacttaaa atcaagcctc aagccagact
    12301 agattctaag tcgtgctata ttgagagatg atttgtttta gttatctagc ccaatgccgc
    12361 cacaagaagt ctgaggctcc ttatctctga cagcaactag cctcccctgc tccagcagca
    12421 gaacacgatg acaaatggcc tgacagatat tagcatcatg cgcaataaaa atataagtca
    12481 gttgatactc ctgctttaac tcatagagca agtccaatag ctgcccttgg gtaatagggt
    12541 ccaagccact caaagcctca tcaaaaatga tcacctccgg ccttaacaaa agagctctcg
    12601 ctatacaaac acgctgtagc tgaccaccac tcagctctct ggccttttta cccagatgag
    12661 tggcgtcaag accgaccgca gctagtattt gaacaacctc ctctaaggca aagtccttag
    12721 aaagggcctc tgtcaatatc tcttgaatag taaagagggg attgactgat cttagcgcat
    12781 cctgaaagac aagtaaaatc cgaggtccac atacttttac agaatagggc tgaccatgaa
    12841 agagcacctg accagctgtc ggctgctcta gcccaatgat taacctagca agcgttgtct
    12901 tgccactacc actttctccc ataatcccaa ggctctcacc cttttccatt tgaaaatgac
    12961 aatctgttag cactggcttt tgatgaaagc tcttataaac atgtctaaac tctatcatag
    13021 cgtatcagcc gatcataatg attttgcaaa agcaactcct tggtggcagc ctgacttggc
    13081 cgatgaaaaa tcgactcaac acttccctgt tcgatgattt ttcccttact catcaccagt
    13141 agttgccctc ccaaagtctg tgccaattgg taatcatgcg tcactgtaat aatggttttt
    13201 cccttgtcct gcaataactt cagcatccgt atgatattag aacgattggc atcatctaaa
    13261 gcagaggtag gctcatctaa aatgataatc tgtgggtcta agcacaacaa aatagctagc
    13321 attacccgct gtagcatacc accacttagc tcaaaggggt acttcctcag cagctcctct
    13381 ggctgctcta gatagagctc tcgcatgaaa ggcagagccc tttttagaca ggcccttttt
    13441 gaaagtctct catggcttcg gatggtttca aggagatgag cctcaatggt ctgaaaggga
    13501 ttgaacatcg ccataggatt ttggaccata taggccatgt ggcgccctct aatgctctgc
    13561 cattgcttag catctaattg atctagtctc atatcttgac aggtaatcct ccctgtcatc
    13621 tgtacattcg acgggcattg accaattaat agcttagtca agagggtctt gcccgaacca
    13681 ctcctgccaa caatcaccaa ggagctcccc aagggcaact caagattgag cttacttaat
    13741 agcacatcag agccattata agccgataaa tcattaacaa ttaaccgttc catgttttcc
    13801 tccacccctt agcatcagcg taatcaccta ggctgttaaa agctagcaca gtcactaaaa
    13861 tggcaagccc tggtgacatc atgagccaca gagctgtcct aaaatagctc cttgcatcat
    13921 gcagcatcat tccccattct gtcacattgg gctgaacacc gatacccaaa aaagaaaagc
    13981 ttgagatcat gagaataata ttgccaatat tcatcaaagc caacactaca atcggccgat
    14041 aaacaaatgg caggatatgc ttttttaaga tatgccgcac agataagccc attgtctgcg
    14101 cactaatgac atatggctct gccttagcgc ttttgaccat cgtgaccatc agcctagcat
    14161 aatacagcca ctctaccaga acaatagcta ggatcatgtt gcctatgccc tgcccaagta
    14221 tccccattgt agctagcgat agtaaaaagc taggaaaggc agaaacaaca tcagctagcc
    14281 acagaaaagc tgcctcgagc cttccttgat accagcctac aaccaaacca accacagcac
    14341 caatagatag ctctaacaaa ctaatagtaa ccgccaaaag caaggaatac ttagccccat
    14401 ataacaagcg cgacagcaca tctcttccca attggtcagt tcctaataag tgctgctgac
    14461 taggtggcat gagcttacta gcaacatcaa cagcatgagg atcaaaggga gcaagataag
    14521 gagcaaacaa gacacagata aacaacagca atagcataac agctgaacca attacgtatt
    14581 tgggcatgct tcctcctttg tcttgcgcag acgagggtca ataaaagaca ctagctcttg
    14641 agttatcaca tggtgtagta aaaacaaagc accaaataag agcatacagg cctgaataac
    14701 cggaatatct gctgctttca gactcataac aaatagactg ccaataccat tccatgagaa
    14761 aatatcctca acaataatag agcccgtcat caaataaaca aaggtcaagc tcaagcctgt
    14821 tgcaatagca ggaaaggcat ttctaatcag gtgatgctta acaatataat aggtcttaac
    14881 ccctcttagc ctggcatttt caacatgcag actcgttagc tgctcactga ttgcctttcg
    14941 tatcaaggca gtatattgcc caatcaagga aaagctaagc gtaatactcg gcaaaatgag
    15001 gctgctggca cccgccttgc ctgacacagg caggagattt agcttaacag aaaaggctat
    15061 aatcaagaga tagcccaacc aaaagctagg cattgacaca gcgacaaagc tgaataaacg
    15121 caccagccga tcaaacaagg aatgctcaaa caaaccactg cctaccccca aaggaaaggc
    15181 aatcacaagt accagtaaaa aagaggtcaa gcttagcatt agcgttgcta aaaagcgctc
    15241 caccaccaaa ggcaggacag ggacctttaa cacgtaagag gtcccaaaat ttcctacaag
    15301 aatgtcagat aaccaggtca catactgctc ccataaaggc ttgtctaagc ccaaatagag
    15361 cctagcattg tgaagagctt ctggtgtaat actgatctta gataggcgca aatactgctc
    15421 tgccgggtta gcggaggata gcttaaccag aacaaaggtc actatcgaaa tcattagcaa
    15481 ggcgccaaag gtagaaataa gcttcttcat catattttct ctcaaccctt cactaagaca
    15541 tcagacaaga attgtcagga tagtcactca caaccagttc ctctgctcta tcaattcttg
    15601 actgccttat cagcagcact tttttcaatg taacgcaatg gaagggcatt ttcctctggt
    15661 gcaaagcgca ttgtcttaaa atctcccttg cgatatactg aaacaactga ctgataggtg
    15721 agtggaatat aaacagcctc atcatgcaac aatgacaata cctgcttata gcccttgtct
    15781 accttatccc catctggctc aatcaaaaca gatttaatca ggcgatcaat ctcagccttt
    15841 gatggcaaac tctccaaggc aatattttct gggtgaccat gatccgcttt tgccgttaag
    15901 gctgtcatcc aagcatgagg atcccaagga gctccccatg aataggtcag catcatatca
    15961 aactgccctg tcttggcatt agcccagtag tcatcctcct ccatagctgt caagaccaca
    16021 tcaatcccaa gctttttcca ctcgccttgg aaatattcaa ccaaatcctt gtctgtcgct
    16081 ttagttgaaa tataaggcac ctgtaaacgc aactgctgac catctttttc cctaatccct
    16141 tcttggtttt ccttccagcc agcggctgtc agcatgtcct tagccttttg gagattgtat
    16201 tcataaggaa ctaagcccgc atcagcatgc ggtgttgttt ttgaaaaaat ggtatctgct
    16261 gctgtctctg ttcctctaaa ggtgtgctta gcaatagcct ttttgtcaac cgcatggttc
    16321 attgcctgac gaacccgctt gtcctgaaac actgactgct tagcatttaa cagcaataaa
    16381 cgagtcgaca tgggctgaga aacatcagta acatacttct tgtccttagc atactgcaca
    16441 aaggtatcaa gactaatcag accatttcca tagatcaaat caatatcccc agcctcaaat
    16501 gctaaggctc ttgtctcagc atcaggcata atcttgatgg ttacttcctt tagctttggt
    16561 ttttctcccc aatagctctc atgacgtgta aaggtaatgt actcatttgc ctttttctct
    16621 ttaacaaccc attgacctgt accaatcggc tttttaacat tgtgcttatt ggtgtcatcg
    16681 ccatcaggaa aaccagcatc agccaaaaac ctaatcggtc tgatcattga caaatcatac
    16741 aaggtagcgc tataagcctc ctttagctta atctcaaagg tatgatcatc taaagccttg
    16801 tagctatcca attgattggt aaagtgaaac caattatgat tgcccttatt ctgctcagag
    16861 aaaatcgaat caaaattccg tttaacattt tgagcattaa aatcagaacc atctgaaaat
    16921 ttagcctgtc tcaggttaaa ggtataggtt ttgccatctg ggctaatcgt ccagctctct
    16981 gctaacgccg gctcaatatt acccttgtca ccatatcgaa ccaagccctc ataaaccatg
    17041 tcttgaataa caaactgatc aggattgtag cgatgaggat tgacatcacc aaaatcctca
    17101 ccccaagcaa tcctcaactg atccgtacgg taagaggcct gcttagcatt ttgacaggcc
    17161 gtcagcagca aagcaaaaaa gaataacaat agcacattca atttagtttt cattatgtca
    17221 ttaactttct aaagatatta atctatctaa ttttagatgt ggtttatcac aaaattaagt
    17281 atggttaatt taatcatttt atagccctct tgtcaagaaa aaatgagaca aaatcagcct
    17341 agaaaaagcc agaaggctac aaataagcaa atcgtcaaaa tcatgaacac ttcaggcttg
    17401 ctgaggaata ttttctaatg gttattagaa ataatgaaca attacctaac aaaagactcc
    17461 aaaataaagg taaaagacga acattcacct tgctgctcag ctaccaagac aaacaatcct
    17521 gatagcatca attttcttta ggctcttagc aattagttgc aatatcagat aattttgaat
    17581 ttaattaaaa aaaacgaaac tacggagacc aattatcaga aagctattca cagccagcaa
    17641 agggcatgct aaagtattat ctggaaaaag aaaggcttag gaatgattat ttctaaacta
    17701 aaaggagaga gacaatgaaa aaaacaatga agaagatgct agcagcctcg acgctctgta
    17761 tcatcatgtc aggcagcttc atcagcggct cagctagagt gttagcggag gaatattatg
    17821 ggtggaatga tgtcactggg tctaagtcac catttcctct atacgtgaca ccaaaaaatg
    17881 gagataaaaa tataaaagtt caacaaacgg ttgtttactg ttttaacagg gatgggcaat
    17941 ggccagaaaa ttgggaaaaa cggatatatg aatctcctga taaagttcca cataaattac
    18001 ccgaatataa taaaaagtca ggaagcgata atctgtttca attacttaat cccaaaatta
    18061 agataaaaaa tccaatggca gctttattag cggttttgga agatggatat cctacgtcat
    18121 cttcttcagg agtaaatcaa agaacaactc agctagctat ttggcatttt acagatggat
    18181 taagcaatct tgcccaattt catcttactc cggaagaaac ttcagcttat aacaagttga
    18241 tagaaaaagg gacaaatgct tctaatcaaa gtgaaaataa actattaaat aaaactttag
    18301 atatttattc ctatatagat gggactggtg ataagaaaca caattatcaa caccttcttg
    18361 gctccactcc aattcctatt gataattcta aagaaaataa atgtcaatgt acaaaagttg
    18421 acttaatgcg aactggagat ggggttaaaa tcattgttta tgttgataac aacggaaata
    18481 atagatatga caacggcgac aaaatgctaa aagaagaaac tatcaaacat ggtcaacgcg
    18541 gacctgctgg tgaatctggg aaaccagggc ctaaagggga tcgaggagaa actggagcac
    18601 gcgggccagc tgggcctcag ggcaaacctg ggaaacaagg acctagaggt gataaaggag
    18661 aaaccggaga acggggacct caaggggaaa aaggtgaacc tggaactcct ggtcctaaag
    18721 gagaagacgg taaagacggg gctcctgggc gtgacggaca accggggcct aagggtgaaa
    18781 aaggtgaccc tggaaaagac ggacaagatg gaaaaccagg ggaaaaagga gaacctggaa
    18841 ttcctggtcc taaaggagaa gacggtaaag atggggctcc tgggcgtgac ggacaaccgg
    18901 ggcctaaggg tgaaaaaggt gaccctggaa aagacggaca agatggaaaa ccagggaaaa
    18961 aaggtgaccc tggacgcgat ggtaaagatg gagaaaaagg cgaacgcggt gaacaagggc
    19021 ctaaaggaga acgcggtgag cagggacctc aaggagagcg tggggagcaa ggacctcgtg
    19081 gggaaaatca tactcctacc ccagacccaa tgcctgagcc ggcacctaaa ccagaatcca
    19141 aacctgaacc taagccgaca cctcaaccag aggttaagcc tctgccagag actaaacctc
    19201 aaaaaccaac caagccgtca gcaatggcta gccaaccaag tagcaaagca ctaccaaaaa
    19261 caaatgacac tagcggctta atgactgtac ttggaacagg cttgctctct cttcttggat
    19321 taggcttcct ggcaaaacgc aaaagaaagc aataactaac acataatcat tagtaatcca
    19381 ttcattatcc atttacaagt tatcataaaa aagccttatc attccttgac tggtatgata
    19441 aggctttttg tttaccctat atagctctac ccttactcca aaaatcactt aaccctagga
    19501 aaaggctgac tatcattttt ggccaaaaaa agacagacac caattcatga tgtctgtctc
    19561 aaaaccaatc ccttttaggg tcagtcctta attacttatt aaaatgaact tggatctacc
    19621 ttgataccca caccttgtgt agttgtgata gatacgttag tcatgtaagt accctttgca
    19681 gtagctggct tagccttaac cattacctca tggaaagcct taaagttttc aaccaacttg
    19741 tcagcgtcaa atgatacttt accaatgata gcttgtacgt tacctgcttt atcagcacga
    19801 taggtaattt taccaccctt agactcttca accgccttag caacgtccat tgttactgta
    19861 ccagttttag ggtttggcat caagttacga ggtccaagga cacgtccaag acgtccaaca
    19921 atagccatca tatctggtgt tgcaataaca acatcaaaat caagccagcc gccattgatc
    19981 ttagcaacaa ggtcatcttc accaacgaag tctgcaccag ctgcctttgc ttcttcagct
    20041 tttgctccac gagcaaaaac aaggacacgc tgagttttac cagttccgtt tggcaacacc
    20101 atcgcaccac gaatttgttg gtctgccttg cgaacgtcga tgtttaagtt ataagcaact
    20161 tctacagaag cgtcaaattt tgcgaagtta gtttcttttg cgagtgctac agcttcctct
    20221 acactgtatg cctttgtgct gtccactttt tcaagtgctg cacgcatttg tttgcttttt
    20281 ttagccattt ttatcttctc cttgtaatgt ggtcatatcg atttgattta aaaatctccc
    20341 acgtcactca tctctatgat gaagtcttgc gggtaataag ggcaggttgc tgattaatca
    20401 gtaacggtga atcccataga acgagcagta ccttcaatca tacgcattgc agcttcaatg
    20461 tttgcagcgt ttaaatctgg catcttagtt tcagcaattt cttgtacttg tgcacgagta
    20521 actgtcgcaa ctttagtttt gttaggtgta cctgatcctt tttcaacacc tgcagccttc
    20581 tttaaaagaa cagcagctgg tggtgtcttt gtgatgaaat caaatgattt gtcttcgtaa
    20641 actgagataa caaccgggat aatcatacca gcctgatcag ctgtacgagc attaaattcc
    20701 ttagtgaatc ccatgatgtt gatacctgct tgaccaagag ctggtccaac tggtggagct
    20761 ggtgtcgctt taccagcagg gatttgaagt tttacaagtt tttcgacttt tttagccatt
    20821 tttaaaaatc ctcctgttgt ggttttggcg gtaattcacg atttttacct cccacaggta
    20881 tgctagagca taccttacca ttatacctta ttagacagat aaatcaagtc attttcacaa
    20941 aaatgttacc gcaaatagca gatgtctcct atggcactag cagtacaagc atgtgaggct
    21001 tccaaggagc cgcttctagt tgacttttaa gcgttttttt attataacaa agctatgcat
    21061 aagaaagtta cgatcaaaga tgtcgcacgc gaggcgggag tttctgtggc tactgtctcc
    21121 tatgtcatca ataacagaga agatcaaaaa attagccctg aaacgcgcaa taaagtgctg
    21181 caaatgatta atcttttaaa ttatcggcca aaccaagccg caaaatcact cgtgacacaa
    21241 aaaagacagc taatcgccct ttactacaaa gagcacagct ctgttttaaa aagagcagag
    21301 cagcttcact ttatcaccca gctatctgcc tttctttaca caaagcacta tcacttgatt
    21361 tgccttaatc aagaatacat cggaaaatat gatgtagcag atgtcattct caccctagag
    21421 gtcaccaaag aggaatttta caagatcgga aatagcaact ttgttccttt gattgctatt
    21481 gatagtatta ttgatgatcc cttatttttc cagattaata gtgaccctca tctcctgttc
    21541 aataaagcca gtgcttattt tgcaggggag ccctttgaac tggttagcct gcctattcaa
    21601 aaccaagaaa tcactcaagg actcgctcaa cagtttgata acatttgctg gattcactct
    21661 atttgcgaca tcgaaagcgt gtctaagggg aatattctag ttattgatga tactgtcaat
    21721 catattctta gtaagcacaa gaacaaacta tacctgccaa gtatctcaga agctaagctt
    21781 ctgaagcttt ttcaggctat tgagtgggct tccaaaagag aagcaatcaa caatcataat
    21841 attttggttt aaccatgata agagcttagc aacaagcttg ctgctaagct ctttttgttg
    21901 gtcaagaggc caactttatt taggtatcag tcagtgtgcc agctctttta gccactaaaa
    21961 gcaggaatta gtttacaagt ctaccaattg ggtataaaat agacttatga tcatctacaa
    22021 attaacagcc ttagccttta ttatcctgac tcccttattc tctatgataa tgatatccct
    22081 attgagactg ggacgaagag gccttaaatt tcctgattta gccttaccac tttttgtttt
    22141 tgaaattgtt attgtatcag gaaaattttt cacccatcat ttactacctt attacctgat
    22201 tgttatgtcc ttgttggcca ttgttatggc actcttactg attatcagaa tccagcagtt
    22261 ttcttaccgc cgatttttca aactattttg gcgagtaggc tttttagtca cactactctt
    22321 ttacctgatg ctagttggtc ttatttttat cgtttagtgc cttaccagac atggcttcaa
    22381 gcctagcagt ctgaatctgc caattaactc tagcactatc actcaaaagg aagctgtctt
    22441 tgaactttct gcttgagtgg gacttttttc aaagcaatca atccatatca aaccagcatt
    22501 agagcatgcg gcttgatacg gattgattgc tttaagaact gttgtaaaat atcaaaaatt
    22561 cagtttttaa taaagtccat tagctatttc tacactaaat atcatttaag aaaacagagg
    22621 ctaataacta gagttcacta taacctaaaa tcaccaatac ctccgattaa cttaatttaa
    22681 ccaaactact gtatatacca aagtttttta cgtgtcatta taatacgttc agataaatca
    22741 tctaatgcac gatctttgtt gagaccaaca tcatattgaa tacccattaa tctatctaga
    22801 aactcaagac gatatttctt cataatattt cgtgagtgtc cttctggaaa atgctcatca
    22861 ataagcgaac ttacaatctc aactttatta ctaattttaa aatagcgact tttcaaagat
    22921 tgtaattctt ctttaattgc tcttaattta gaaaaactat ctgctccata aaccttagct
    22981 tccatttcat tagcctcaga ataacttagt tttattgttg caataaaatt tctaagtact
    23041 tccttctctt ttttaagctc cctttctgtc ggactcattc tatagtaata ttgacgccaa
    23101 cgatattgag aagcgttgac tttttgatca cttatagtca aaatagtcaa tgctactaca
    23161 ctaaagaaaa atattctttt cgtttgcagt ttctcctata cttcataatg tactatttgt
    23221 atataaacac aacataacca agcattagta tatcagaaaa ctttcttaaa tatgtgatat
    23281 tagctaatct ttttttaaaa ctctctatat attaaggtat tatggacata ttgacttagc
    23341 agattagatc tgccaattag ctctagcact atcactcaaa atgaagctgt ctttgagttt
    23401 tctgcttgag tgggactttt tcaaagcagc atatcaaaaa cccgtatcaa gccacatggt
    23461 taagcttagc ttggtacggg tttgttttat gatgagcctt tagatgagct cttttttaat
    23521 tggtttgcag tacctttctt ggcttagtcc cctcagctgg accaatgaca ccggcctctt
    23581 ctaattcgtc cattagtcga gttgctcggt taaagccaac cgatagacgc ctttggagca
    23641 tcgaggcgct tgccttttgc gtttccaata caagagcctt tgcttcctca aaaaggggat
    23701 caccctcagg agctccgctg ctgccataat cagagtcact aacctcaccc ggatcaaaat
    23761 aatcatcata atcagcctct gcctgctcct tgataaagct aacaatgcgc tcaacatcat
    23821 catctgaaat aaaggagcct tgcagacgca cagggtgatt ctcatcaatc ggcttaaaga
    23881 gcatgtcccc gcgaccaagc agcttttcag cgccattttc atcaagaatg gtgcgactat
    23941 ctgttcctga tgaaaccgca aaggcaatac gtgatggaac attagcctta atcaatccag
    24001 aaataacatc aacagaaggt ctctgagtag ctaaaatcat atggatacct gctgcacgcg
    24061 ccttttgccc aagacgaata atagcatcct caacctcctt actagccacc atcatcaaat
    24121 cagctagctc atcaacaata acaacaatca tcggcaaagg gatttgcttt tgctcagatt
    24181 gcttgttgta ggcttcaacc ttggcattgt agcctgcaat atttcggaca ccgaccttac
    24241 tgaacagctc atagcgattt tccatctcat caacaacctt ctgaagcgct ttgcttgctt
    24301 tacgagggtt ggtgaccacc gggattaaca ggtgaggaat gtcattataa acagacagct
    24361 caaccatttt cggatcgacc attaggaatt tgacctgatc cggtctagcc ttcattaaaa
    24421 tactggagat aataccgttg actgcaacag atttccctga tcctgttgag ccagccacca
    24481 gcaaatgagg catgcgggtc aaatcaaagc ttctggcact accgttgaca gccttaccaa
    24541 gaggaatttc caataatttg tcatcagatg tgttggattg ctcccaaagc tcgcggaaag
    24601 aaaccgttgc aacctctgaa tttggtacct ctatacccac aagggatttg ccagggatcg
    24661 gagcttcaat ccgtacgtcc ttggctgcca aggccaaggc caagtcatca gctaaattgg
    24721 aaatgcgatt cacacgaaca ccaacagccg gcttaacctc gtatttagtt acagatggcc
    24781 caatctctgc ccgctccacc ttgacgtcaa ttccaaagct tctgaaggta tcctctaata
    24841 ccttgatatt ttgacgaaca aggtactttt ccttgaattg atttttaggc ttatcagcag
    24901 caaacagctc tatcgtcggc agcttgtaaa gcagattggt ctttggcgtg aaatcgacct
    24961 ccactgacag ctcctcatca tctgacagcg gcgcctctcc tgcgattgct gaagcacccg
    25021 ttagaggggc ttctggtaca gactcctctt catctccaaa tgcctcaggc tcatcatcag
    25081 cagggtgtga gtcataggcc agaatttccg gctcaaaaaa tgcttcagac tccttctgat
    25141 cagccatctc catcaatagg tcttctggct ctgctaaaag ctcacctgtc tcaggattaa
    25201 tcgcttgatt ggccagatat tcttgctcct ccaaggcctc tcttgctaga cgctcctctt
    25261 cagccagcaa tcgttgcttt tctcgctcaa caaaccgctt ttccttgttt tcttgatagg
    25321 ccagggatag cttttcaaaa agcgtcttaa caaaatgact gacgtcataa atatcccaag
    25381 gggtcattaa aaacaagccc agcaggataa acaaaaaacc aataaaataa gagccaatat
    25441 tagaaaacaa gaaggaaata ggcttgtaca gcatggcccc aagcatacca ccaccaacaa
    25501 actcgctaac cttaaaggct agcaggtcat tggtgattag ctggatagtc ccagcaacaa
    25561 tagcctgatg agctagctga ggcaatgaga aaagataggc atgccattca accagaagcc
    25621 ctaaaaacaa gatgataaag ccagcgataa ggccatcttt ttgcctgagc cacttgaaga
    25681 aaaagaggta aaaaaggacc gccaacatca agagattggc taagtcgcca accataaagc
    25741 gaataagatt atataaggta accccaagcg cacctaagcg aagcatggca aaaacaagca
    25801 ataaagcgca ggagaaagaa gcaatcattc tcttaatagc cttttgcttt tcaagctctg
    25861 cctttgttaa acgtctctta gggggatttt tttgtcgttg agttcttcta gccatagcct
    25921 tattataaca ttttttaatc gttatgaaag atgacattaa aattctcaat aaatagatga
    25981 agctgcttga ttttatgcta taatgtcaat cataagaaca aataggagtt gaagatggaa
    26041 aaagaattta acaccttgac ctatggtaag cttcccctgc aaattgatat ggggcatggc
    26101 aagctaattc ccaaaggagt tgaagtcaag gctatcgttg atatgcagac cgggcaagtc
    26161 accttcaagg tttctcagga ggacttagag aagcttagaa atagttaaaa aatagacttc
    26221 gtctcaatgc cctttagctt tattttccaa gtcattttat gttaaaataa aagaaattgt
    26281 tctaaggagt acacatgaaa aaactactat cttttggctt aatcggtctt gctttgctta
    26341 gcttaagtgg ctgtgagtcc attgatcgtg ctattaaagg tgatgaatac gtcgatgaaa
    26401 aaatcgctag agaggaaagc gagacagcag caaaggctta tgaagcaaaa atcaaaaaag
    26461 cactcaaggc tgacgctgat cagtttccac aattaaataa agaagtcgac aaagacgaag
    26521 ctaaggtcat tatcaaaact aatcagggcg atatcaccct caagctcttc cccaagtatg
    26581 caccgcttgc tgttgaaaac tttttaacac acgccaagga aggctattac gacaaacttt
    26641 tgttccatcg ggtgattaat aactttatga ttcaaaccgg tgatccaaag ggagatggat
    26701 ctggcggaga atccatttgg aagggcaagg acagcaaaaa agatgcggga caaggctttg
    26761 ctaatgaaat ctcaccattt ttatataaca ttcgaggggc tcttgctatg gcaaatgccg
    26821 gtgcagatac taatggcagc cagttcttca tcaatcaaag caagctcaac caagccaagg
    26881 ccttatcaat tgataattac tctaagccaa tcattgactc ctacgaagaa gggggtaatc
    26941 ctagcctaga tggtggctat accgtttttg gtcaggttat tgagggtatg gatatcgttg
    27001 ataaaatagc tgccagccca gtcggcccaa atgacaaacc aatagagaac atcactatta
    27061 atgctattga cattgttaag gattactcct ttaaaaaata gcctctaagc tacaacaaca
    27121 ataaaacgac cagctcctta tcggaaaagc caccgattca agagctggtc gtgatttttt
    27181 gctatcaatt aaataaagaa gctagcctat tgatcatatc attagcagct atccattcac
    27241 agccagctat ggtttactag gaatgctttt taaagtagcc ctgcttaggc gaaacaaaga
    27301 agctaatcag aaacaccaca gccgaggtca aaacaatgct tgagcctgct gcaatattaa
    27361 aggtgtagcc caaatagagc cccaacacag aggtcatagc tcccaagcat gaggagataa
    27421 ccagcattac ctttaggctg ttagcataca aatacgctgt agccgctggc gtaatcagca
    27481 tcgccacaat caaaatggta ccaacacttt gcatagcagt caccgaaacc aaggtcaaca
    27541 aaatcatcaa cagataatga taagcagtga ccttcattcc catagacctt gctagcacag
    27601 gatcaaagga ggtaatgagt aattccttaa agaagaggac aataatagcc aaaacaaaaa
    27661 ccgaaacaat gatcgtaatc catttgtcac tgtcttgcac tgctaggata tttccaaaga
    27721 ggatatgaaa aagatccgtt gagctattag caatcccaat cagaataacc cctaaggcaa
    27781 gaaaagagct aaaggttatc cctattgctg tgtctccctt gataacagag ttttccttga
    27841 tgtaggtaat gataacagag gctagcaagc caaagacaat agcccctaca aaaaaattaa
    27901 tccctaaaat aaaggacaag gctactcctg gcaaaacagc gtgagaaatc gcatcaccca
    27961 ttaatgacat ggacctaagg ataataaagc agcctactgc tcctgataca ataccaataa
    28021 caacggctgt aataagggca ttttgtaaaa aatgatagga catcaggccc tcaaaaaact
    28081 tcaaatacat ttaaaacatt ccctttccta agaatagatg atcaccatag gcctttgata
    28141 gggtttcaac agtgaacacc tcatcaacag atccataagc gatcagctct ttgttcaata
    28201 ccactaactc atcaaagtaa tgctctacct tgcttaaatc gtgatgaaca attaaaatcg
    28261 ttttgcctgc ttttttcaag tccttgagca ggtcaatgat gattttttca ctaaccgaat
    28321 caatcccaac aaagggctca tcaagaaaaa tatagtctga ctcctgaatc aagcatctag
    28381 ctactagcat acgctgaaac tgaccaccag aaagagattt tatcggacga ttaccaaagc
    28441 cagcaagccc aacctgctct agcagctggt caacctgatc atattctttt tttccgacac
    28501 gacgaaaaag ccctagccta gtgtaggtcc ctaatgagac gcactccttc accgtaattg
    28561 gaaagttgta gtcaatcatg ctgcgctgct ctacataagc aatcgtatgc cccagccttc
    28621 gaccgtcctt ttgatcaaca gttacttggc cactataatc taaaagattg agcatagcct
    28681 tcatcaaggt tgattttcct gcaccatttg gcccgataat cccaacgata gctggtcctt
    28741 tgatttgtag tgagatattg tctaaggctt ttacgttacc gttatagcta accgaaagat
    28801 tttgcgtatc aatcattttt tctccttaat acaaacaaag cacaacacca gaagctgctg
    28861 tgctttattg ttatattatt ttgctaagcc ttcagaaatt ttatcaaggt tccatttcat
    28921 catggcatag tagctgtctc catcttggcc ttttttggct acagagtcag taaagatttc
    28981 tgcatagatc ggaataccac tgtccttaga aacagtctcc attggacgtc tgtcaacact
    29041 tgactcaaca aaaagcgctg atggcttaac gtctttcaat ttttcgatca atgatgaaat
    29101 ttgatccgga gttccttctt cttcagtgtt gatttcccag atgtaggctg atgggacacc
    29161 gtaagctttt gagaagtatt tgaagcagcc ttcacttgtg acgattagct ttttattgtc
    29221 agcaatagca tcaaattttg attttgcttc cttatcaagc ttctctagct tctcaacgta
    29281 agcttttagg ttgttttcat aggtttcctt gtttttaggg tctttagcga tcaattgctt
    29341 tgcaatattt tttgaataga taaccccatt ttcaagattc aaccaagcat gagggtcttc
    29401 cttgcctttt tcactttcac cttctaggta aatcacatca ataccatcag atacagcgaa
    29461 gtagtccttg tccttttcct tcttagcatt ttttacaagc tttgtaaacc aagcctgtcc
    29521 gccgtcttca aggttaatac cgttatagag aataagatcg gcattgctgg tcttctcaac
    29581 gtcttctggc aatggctcat actcatgcgg atcttgacca atcggcacaa tgctgtgcaa
    29641 gtcaatcttg tcacctgcaa tatttttagt catgtcagca ataatggaat tggtaaccac
    29701 aaccttgagc ttgtcactct tagcttcctt gtttccacca ttagagcagg caaccagcat
    29761 gaaaacagcc aaaaaagcac tcaaggcgag gctaagtttc tttttcatca gttatctcct
    29821 taggatctat tatttaatta attaagtata gttaattatg ctattagcat aacttttttt
    29881 taggcctttg tcaagatttt tatgaaataa tctgatataa taatcattat aaataagaga
    29941 aaggctttta gacatgacgc ctaataaaga agactatttg aaatgtattt atgaaatcgg
    30001 agagcaaaac attaaaattt ctaacaaaat ggttgcagag agaatgaagg tttctgcacc
    30061 cgctgtgtca gaaatgatta agaaaatgat cgcacaaggc tggattgtaa aggataagac
    30121 ctgcggctat tatctaacag agcaagggca gcgcttagtg gcaaatcttt atcgtaagca
    30181 ccgattgatg gaggttttct tgatccatca actgggctat actgctagag aggtgcacca
    30241 agaggctgag gtactagagc atactgtgtc agatatgttt attgatcgct tggataaaac
    30301 ccttggctat cctacttttt gccctcatgg agggacaatt ccacgccgcc agcagccact
    30361 aatcgaaatc aacaaaacaa cgcttaatac tattaaagag ctgggaattt ttcgtttgag
    30421 cagggtgcat gatcactttg agcttatcca gtacctagaa gcacaccagc tgacgatcaa
    30481 tagtgagttt agactgattc aaatagatga cttcgcaaaa acctatacca tcacttatgc
    30541 agataaggaa ttgatcattc ctgaaaacat cgccaagcag ctctttgtta ctgctattta
    30601 aataaaaaaa gacctgatat ttgctgtcac cacaggctat caggtttttt tggtcatcat
    30661 tttttatcag gtaaggcctc taaaaaggct atcaagacct tggctgattt ttttccagcc
    30721 tcaacaataa actgatcgaa ggtcatatta gcatcgtggg ccgctgtgtc actcatcgcc
    30781 ctaacaacaa taaatggctt gccagcagct tgagctgcct gtgccactgc tgctccctcc
    30841 atttccactg ctaaggtctc tgggaaatgt gctttgatgg tatcaatact gtcttggccg
    30901 gcaataaagc tatctcctgt tgcaatcagg ccaatccgac tattggtctt ttcctgatca
    30961 agcacctgct taaaggtctc aaccagcttg ctatcactgt caaagtaaag gggctgcgca
    31021 gccatttgac catagtcata gccaaaggcc gtcacgtcca catcatgata caccaagcga
    31081 tcagcaacaa caacatcacc aatagccaag ccactagcta ttgctccagc cgatcctgta
    31141 tttataatag cgtcagcctg aaaatgctct gctagcatcg caactgtcat cgctgacatg
    31201 acctttccaa caccagattg gactaagacg agctcatggc gaccaagacg acctgtatag
    31261 taggtattgg aaagcacctg atgctcttga ctatcgtgga gctgctccaa taaaaaccgc
    31321 agctcctctt ccatagccgc aataattcca attttcatat gatatcctta tttgtttttt
    31381 tctataaatt aaagaccgca taaaccaaga gagcaatcaa gacaagcacc gctaagagaa
    31441 tcagatttaa ccgcgattga aagcgactgc gctttgcatt ttcaattctg cgacttttgt
    31501 aaatacgatc agtatgctta tcctcaaagg tcatgatttt ggtttcaaaa tctgcataat
    31561 cgtcaggctc aaactgttct ccgcgctgag ccttttcgat aatgtcatca gtcagcaagg
    31621 gcttgcccat tacacatcac ctccaaaatg aagggcgtaa tattgcaggg caatgatggt
    31681 tttagcatcg acaagctttc cttgtgccac tagatccata cattcttgat agctcagctc
    31741 aagaagctca atcacctcat ctgcgtcctg tggtctagga ttggcaactc tctgcaggtc
    31801 tgtcgccaag tacagcttaa ttttttcatt acaaaaacca atcgctgtat aaaactcgtg
    31861 aataagacgc aaatcaccag aataggcggt ttcttcctcc agctctcgtg ctgctgcttc
    31921 taatgctgag ttggcctcac cgacctctag ttttccagca ggaatttcat aagaaatcgc
    31981 ttcgatagcc ttacggtact gcttgacaat taacagctta cgctctggcg ttacagccaa
    32041 tatagcgact gcaccgcgat gaaaaatcaa ttcgcgctta gcctgaccta ggccgtttgg
    32101 caattggaca tcatctaccg caactttgaa aatgtgacca tcaaaaatct cttgcctttt
    32161 aatcgttttt tcttcaaaat ccatgtctga tctccttgct ttctctccat cattttactt
    32221 tgcttgattt gggtgatgtg gcagcctctt ggcatagccc tccttcacca cctgacggct
    32281 gcgccctata gccacactgt ctgccggcac tgactgggct atcgtagacc ctgcggctgt
    32341 taaagcattc tccccaacct ctactggagc tatcaaagtc gaatgactcc caataaaagc
    32401 gtgatcgcca atcactgtct ggtatttccg ttgaccatca taattaaccg taatgcttcc
    32461 tgcaccaata ttaacctctg agccaatctc ggcattcccc aggtaagtca aatgccctgc
    32521 cttggtattg gcccctagat gagacccctt aacctctaca aagttcccaa tatgaacgct
    32581 ctcatcgagc tgggagtctg ggcgaatgtg cgcatagggc cctactgtca caccatctgc
    32641 taggactgaa tcctcaatca ctgactggct caccactacg ccctcaccaa gcctcgaa
//
LOCUS       DARYVE010000020        31750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYVE010000020 DARYVE010000000
VERSION     DARYVE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..1435)
                     /locus_tag="TVW25_000852"
     CDS             complement(<1..1435)
                     /locus_tag="TVW25_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1378504.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TVW25_000853"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TVW25_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1378505.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TVW25_000854"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TVW25_000854"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1378506.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TVW25_000855"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TVW25_000855"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1378507.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TVW25_000856"
     CDS             complement(5344..6630)
                     /locus_tag="TVW25_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1378508.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TVW25_000857"
     CDS             complement(6772..7143)
                     /locus_tag="TVW25_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1378509.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TVW25_000858"
     CDS             complement(7130..7402)
                     /locus_tag="TVW25_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1378510.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TVW25_000859"
     CDS             complement(7433..8944)
                     /locus_tag="TVW25_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1378511.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TVW25_000860"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TVW25_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1378512.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TVW25_000861"
     CDS             complement(12410..12979)
                     /locus_tag="TVW25_000861"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1378513.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TVW25_000862"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TVW25_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1378514.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TVW25_000863"
     CDS             complement(14337..14702)
                     /locus_tag="TVW25_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1378515.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TVW25_000864"
     CDS             complement(14823..15020)
                     /locus_tag="TVW25_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1378516.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TVW25_000865"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TVW25_000865"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1378517.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TVW25_000866"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TVW25_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1378518.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TVW25_000867"
     CDS             complement(17976..18749)
                     /locus_tag="TVW25_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1378519.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TVW25_000868"
     CDS             complement(18869..20092)
                     /locus_tag="TVW25_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1378520.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TVW25_000869"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TVW25_000869"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1378521.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TVW25_000870"
     tRNA            complement(21081..21154)
                     /locus_tag="TVW25_000870"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TVW25_000871"
     tRNA            21435..21506
                     /locus_tag="TVW25_000871"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TVW25_000872"
     tRNA            21539..21612
                     /locus_tag="TVW25_000872"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TVW25_000873"
     CDS             complement(21873..24458)
                     /locus_tag="TVW25_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1378522.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TVW25_000874"
     CDS             complement(24581..26200)
                     /locus_tag="TVW25_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1378523.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TVW25_000875"
     CDS             complement(26280..27152)
                     /locus_tag="TVW25_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1378524.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TVW25_000876"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TVW25_000876"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1378525.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TVW25_000877"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TVW25_000877"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1378526.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30654..31046
                     /locus_tag="TVW25_000878"
     CDS             30654..31046
                     /locus_tag="TVW25_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1378527.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31121..31522
                     /locus_tag="TVW25_000879"
     CDS             31121..31522
                     /locus_tag="TVW25_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1378528.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31519..>31750
                     /locus_tag="TVW25_000880"
     CDS             31519..>31750
                     /locus_tag="TVW25_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1378529.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDS"
BASE COUNT         9884 a         6363 c         5841 g         9662 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga aatatagaaa
    30541 tcatgttaaa ataatattat taaatagtta aattaaaaag aaatatacca aaatgattcc
    30601 atttattttt gggaatttat cgataagtat aggaatgata taggagtata gacatgaata
    30661 ggtttttaaa gatcagtctg cttattgttg gtgttattgt cattatgctt ggcatggaag
    30721 taaagcatag aatggatata tacgatcaaa tcaagcagga ggagataaaa attgcccaaa
    30781 gtaaagaagc aattgtgatt tatgaacagg agttaaaatg gttggaccca aatgcattga
    30841 caaatgaagg gactattaaa tcctattcta ttgatttaga ctcaataact cttaatccaa
    30901 tgggaggctt ttccattgct ttacatataa acaaaaatcc aaagtataag tatcgaataa
    30961 gtttaatgtg gaatacacca atgagagatt tatgtgtggg aggatcctct ttgtcgccag
    31021 aattacaaga attgttagat aggtaatgat tatgacaggc tatcagaaac aattgattgc
    31081 accaaagaac aatataattt tcatgaaaag gagcatagtt atgaaaacat tgttaaaact
    31141 cattgtattt attgttggta ctcttgtact tatgcttggc atggaggtaa agcatagaat
    31201 ggatacatac gatcaaatca aacaggtaga gctcaaaaac gcgcatagta aagaagtgat
    31261 tgaaatgtat gaacaggagc taatatcaat ggatccccag gccctaacag atgaaggact
    31321 tatcaagtcc tacactatcg actcagattc actctttatt aatccgatgg gaggcttttc
    31381 cattcattta attatcaatg atgatccaga tatttacttg agagttggcc ttggtagata
    31441 tgatatggaa agaaatttgg agattgatgg tatctatcgc tcagaaaagt tagaaaaact
    31501 actaaaagga gtggagagat gaaaacattg ttaaaactta ttgtatttat tgttggtgcc
    31561 cttgtactta ttcttggcat ggaggtaaag catagaatgg atatatacga tcaagtcaaa
    31621 caggtagaac tcaaaaacgc gcatagtaaa gaagcgatag acatttatga aaagaagtta
    31681 aaaagattgg atcctcaggc cctaacagat gaagggctta tcaagtctta tactattgac
    31741 tcagactcaa
//
LOCUS       DARYVE010000021        31392 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYVE010000021 DARYVE010000000
VERSION     DARYVE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31392
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..174
                     /locus_tag="TVW25_000881"
     CDS             <1..174
                     /locus_tag="TVW25_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378530.1"
                     /translation="EAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIA
                     AGTIAIPKRKEED"
     gene            complement(420..734)
                     /gene="trxA"
                     /locus_tag="TVW25_000882"
     CDS             complement(420..734)
                     /gene="trxA"
                     /locus_tag="TVW25_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1378531.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            914..2233
                     /locus_tag="TVW25_000883"
     CDS             914..2233
                     /locus_tag="TVW25_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1378532.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2573..4909)
                     /locus_tag="TVW25_000884"
     CDS             complement(2573..4909)
                     /locus_tag="TVW25_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1378533.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IEIAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(4982..5527)
                     /locus_tag="TVW25_000885"
     CDS             complement(4982..5527)
                     /locus_tag="TVW25_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1378534.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5527..5838)
                     /locus_tag="TVW25_000886"
     CDS             complement(5527..5838)
                     /locus_tag="TVW25_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378535.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            5956..6864
                     /locus_tag="TVW25_000887"
     CDS             5956..6864
                     /locus_tag="TVW25_000887"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1378536.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6889..7488
                     /gene="lepB"
                     /locus_tag="TVW25_000888"
     CDS             6889..7488
                     /gene="lepB"
                     /locus_tag="TVW25_000888"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1378537.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7717..10116
                     /locus_tag="TVW25_000889"
     CDS             7717..10116
                     /locus_tag="TVW25_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1378538.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10212..10697
                     /locus_tag="TVW25_000890"
     CDS             10212..10697
                     /locus_tag="TVW25_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378539.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TVW25_000891"
     CDS             complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TVW25_000891"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1378540.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12152..14476
                     /gene="pflB"
                     /locus_tag="TVW25_000892"
     CDS             12152..14476
                     /gene="pflB"
                     /locus_tag="TVW25_000892"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1378541.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14782..15060
                     /locus_tag="TVW25_000893"
     CDS             14782..15060
                     /locus_tag="TVW25_000893"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378542.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15224..16165)
                     /locus_tag="TVW25_000894"
     CDS             complement(15224..16165)
                     /locus_tag="TVW25_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1378543.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16162..16917)
                     /locus_tag="TVW25_000895"
     CDS             complement(16162..16917)
                     /locus_tag="TVW25_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1378544.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17410..18258)
                     /locus_tag="TVW25_000896"
     CDS             complement(17410..18258)
                     /locus_tag="TVW25_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1378545.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKGSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18360..18812)
                     /locus_tag="TVW25_000897"
     CDS             complement(18360..18812)
                     /locus_tag="TVW25_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1378546.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18832..20031)
                     /locus_tag="TVW25_000898"
     CDS             complement(18832..20031)
                     /locus_tag="TVW25_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1378547.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20200..20859
                     /locus_tag="TVW25_000899"
     CDS             20200..20859
                     /locus_tag="TVW25_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1378548.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20880..23165
                     /locus_tag="TVW25_000900"
     CDS             20880..23165
                     /locus_tag="TVW25_000900"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1378549.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23271..23663)
                     /locus_tag="TVW25_000901"
     CDS             complement(23271..23663)
                     /locus_tag="TVW25_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1378550.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23817..24074)
                     /locus_tag="TVW25_000902"
     CDS             complement(23817..24074)
                     /locus_tag="TVW25_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1378551.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24253..24627
                     /locus_tag="TVW25_000903"
                     /pseudo
     CDS             24253..24627
                     /locus_tag="TVW25_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24885..25667)
                     /locus_tag="TVW25_000904"
                     /pseudo
     CDS             complement(24885..25667)
                     /locus_tag="TVW25_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26184..27692)
                     /locus_tag="TVW25_000905"
     CDS             complement(26184..27692)
                     /locus_tag="TVW25_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1378552.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            27943..28839
                     /locus_tag="TVW25_000906"
     CDS             27943..28839
                     /locus_tag="TVW25_000906"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1378553.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28887..29099
                     /locus_tag="TVW25_000907"
     CDS             28887..29099
                     /locus_tag="TVW25_000907"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1378554.1"
                     /translation="MQSLEGGNSPIVEQNYGSTEGYHGQSGILEETEDTNPPGIILGG
                     SGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29026..29832
                     /locus_tag="TVW25_000908"
     CDS             29026..29832
                     /locus_tag="TVW25_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1378555.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30204..31250)
                     /locus_tag="TVW25_000909"
     CDS             complement(30204..31250)
                     /locus_tag="TVW25_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1378556.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31252..>31392)
                     /locus_tag="TVW25_000910"
     CDS             complement(31252..>31392)
                     /locus_tag="TVW25_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1378557.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9383 a         7384 c         6253 g         8372 t
ORIGIN      
        1 gaagctaaga agcctgaaca acctaaacca atgactaaac caggagctaa gaagcctgag
       61 caatcacttc catcaactgg tgacatcaga aatccattct tcacgcctgc agctattgct
      121 attatgatcg cagcaggtac cattgccatt ccaaaacgca aggaagaaga ttaaacaaat
      181 taacaatccc catatttcaa caatgataca caagccccta cttgtgtcca cctcaaaagc
      241 agtagccagt cgcgcggcta ctgcttttac tatgcttttt ttacaccagc tctgatagca
      301 gctaataaca aaaaagattg aagacacagc ttattgggtc cccgatcttt ttttggtcat
      361 acaaccaaca gcagctcttg aggcttgctg tccttctaag aggctgttgg cttgttgctt
      421 tagcttaatt ctgctacgat agccttgatt tgatccttgg tatggacgcc tgctacttgc
      481 ttgacaacct taccgtcctt tttgaacagc agggttggga tagacataat gccaaattgt
      541 tgagcagtat tgggattgtc atcaacatct agcttgacaa tcttaagctc agcttcgtca
      601 atttctgctg ctaattgatc aaggattggc gcttgcatta agcaagggcc gcaccaggtt
      661 gcccaaaagt ccacaaggac taggccttca ttagtttctg cttcaaatgt tgcatctgtt
      721 acgatatgtg ccattgtaat ctccgttctt atagtttata agcctatttt aggggaaaac
      781 gactgataat gcaagaatct gatacgaaga cctcggtctt atgatttaag aaaaatctgg
      841 cgtagccatt ttaagacaaa tacgctggcc tttgctacaa tgaccttatc ttaacaacta
      901 aaaggaggct actatggaag catacgagct tattgtgatt ggatttggta aggccggaaa
      961 aactttggct gccaaaatgg cgcagctagg aaaaagagtt gcccttattg agcagagccc
     1021 cactatgtat ggcgggactt gtatcaatat cggctgtatt ccaacaaagg ccttaatcac
     1081 tgctgctgag cataatgcta gctttgcaga cgctatggcg cacaaagata ctgttgttca
     1141 tcgtcttcgc caaaaaaatg agcagctgct agctcagtct ggtgtgacac tttacaacgg
     1201 taaggcaagc tttgtctcta ataagacgat tcaagtagaa gcagggcagg agcggatcct
     1261 cttagagggc aagcatatcg tgatcaatac cggagctgtt tcaaatcgct ttccgatacc
     1321 tggtctagca gatagtcagc atgtggttga tagtacaggg attctagctc tcactgagca
     1381 gcctcagcgc ttggctatta tcggtgcggg gaatatcggg ctagaggttg ccagccttta
     1441 tgccagctta ggcagcgagg ttactatgta tgaggctgca cctgctattt tagggcgcta
     1501 tgagccggtt gtcgctgagc tggcacagga ttacctggaa aaagctgggg ttacctttaa
     1561 gctctctgcg actgttgagc tgattgctaa tgatgaagca ggtagagttc tagtgactgc
     1621 taatggcaag acagaagcct ttgattgtct cctctatgct atgggacgta agcctgccac
     1681 tcaaggcctt ggcttggaaa acactgacat taagcttgat gatcgctatg ctgtcgtggt
     1741 agatgattat tgtcaaacca ctgtcgaggg gctatatgcg gttggtgatg ttaatggcgg
     1801 gcctcaattt acctatacgt ccttagatga tttcaggatt gtgtttgggc agctaacagg
     1861 cacaagccag tacaaccaca aagatcgggg ctatctgcca acaacagtct ttatcgagcc
     1921 gccactttca caaattggtc taacagaaaa agaagcaaaa gagcagggac tgccctacaa
     1981 ggctaatgag ctcttggttg ccaatatgcc acgcgcccat gtcaataacg acctcagggg
     2041 gatttttaag gtcattgtca atacagagac taatgaaatt ctaggggcaa ccttatttgc
     2101 taacaattct cacgaataca ttaacctgat taagatggct atggataacc agattccata
     2161 tacctatctc aaaaaccagc tctttaccca cccgtcaatg gctgaaaatc ttaatgatgt
     2221 ctttaacctt taaaagaacc tcaacctcac ctgcatagca ggtacaacag ccaaactatt
     2281 aaaaaaacaa actccttttt ggctgcttat cacatggata ggcggctagc aaaaggagct
     2341 tgttttttct tgtatccaat cagcaggcta gcagctgctc atggtctaaa ggaactagct
     2401 aggctgggac acgttggtag caaaagtcca gcaagactca ctagctgctg tcatgagctt
     2461 tgaagagcag cacttaggga acacgcccag tagctttctt tgggacgctt ggctcaccta
     2521 gggctcaatc agcttgagta aaaaggggct ttatttgaat caagaggatc aattagccta
     2581 gattagctat ggtacagcct gagccgccag cattttgcgg ggcatagcca aagcttttga
     2641 catgcttgtt gcgtcgcaag tacttgccga ccgcttcacg tataacacct gtaccaatac
     2701 catgtatgat gtcaacctga ctcatgttgt taagcaaggc ttggtcgata aaggcatcta
     2761 gctcctgcat ggcctcctca tagcgcttgc ctcgaaggtc taagcgagcg cgcggccctt
     2821 ttcctgtagc tgcttttttg acgaccttga cagctctctt cttaggctgc tgcgcttctt
     2881 cttttagctt aaccaagctg aattcgtctt ccttgagggt caacttgatc aggccaacct
     2941 gagcctccca cctcttgtcc ttaagctggg caagcaaggt tcctctttgc ccataggcgg
     3001 taacaatgat gtcatcaccc acacgaggag cccgccattt tttcgctttt ttcagcacct
     3061 tattttgcga caggctttgc tctggcgcaa gctgctttag gcgatgcttg gcttcgataa
     3121 tttcgtgcgg ctttagctct gccttttcat gcagctgact taaaatgcta tcactttctg
     3181 ccaaggctat atccacaatc tcacgcgctt caagggctgc cttttccaat tccttgtcct
     3241 tagcgtggga gaactcgtta tagagctttt taacagcacg attgaatttg aggttatcct
     3301 gctcgacctc cttgatatgc tcaaggcgct tgcggctttc taacgtttgc tgctctagtt
     3361 gctcaatgat acgattgaca tcatgatcag ttgcggtcat cgcctgagct tccttgacga
     3421 tgtgctctgc taagcccaat cgtctcgcaa tgtcaaaagc atttgagcga ccaggcactc
     3481 cttgcatgaa gcggtaagta ggctttaggc tgacattgtc aaaggccatg ctggcatttt
     3541 caacataggc tatctcaatc ccataggcct ttagctctgg gtaatgggta gtggccatcg
     3601 tcttaatatt ggtcagacgc agctgctcca aaatagccat agcaaggctg gctccttcct
     3661 gtggatcagt ccctgctcct agctcgtcaa agaggatcaa gctgtcactg tctgcctgat
     3721 tgagaatctc aacaatgtga gtcatatgac tggaaaaggt agacaggctt tgctcaatgg
     3781 attgctcatc tccaatatca gcataaatac cattaaaaac tgccaccctg gagcccttgt
     3841 cagccaaaat aggcagccct gactgggcca tcacctgagc aagccccaag gttttgagca
     3901 tgatggtctt accacctgta ttaggaccgg tgatcacaat tactgctaag tcatttgcaa
     3961 aatgcagatc atttgccaca gggttttgaa tcaaggggtg gcgcgcattg agcagctgta
     4021 agcttttatc gtcagaaatc actggcacag ttgcctgttt ggcttgcata taaaggtatt
     4081 ttgctctcac aagatctaaa tgtcctagta gccaagcgtt attcctaaga gatcgactat
     4141 gcggacgcag ctgctctgac agctcatgca agattcgtcc aatctcatgg cgttcatctg
     4201 tctgtagctg agtcagctcc tcattgagac ttacaagcgc tctaggctca atgtagaccg
     4261 tactgccaga agctgacatg tcatgcacaa cgcctgccac cttatgacga taggtgtttt
     4321 tgacaggcag gacacttcgg ccattacgac tagcaatcag gctctctgac aaataagctg
     4381 cctgtttttt taggatatcc tgcaggagct gacgactggc atgctccttg tttgatatct
     4441 gacgacgaat gctctccaat tcaggactag caaagccttc aacaaagcct gcgtcattaa
     4501 tggcttggag actcccctgt aagctaggaa agctctctat tttttcaaag agtgctttta
     4561 gagcgactaa atcaacattt tccaaatcag cgtaaaaacg acagacctct gccgacacct
     4621 gcaggagctt tttaactgct aaaagctctt gaatgctcag atctgcctct aaatccaaac
     4681 gctgcatgct ttctgagaca tctgatagcc ctcccaaggc aaaatggtgg tgctctacaa
     4741 aaatagccgc catttcctca agctctgtaa agtaagcctg tattttgtct ttattcgcaa
     4801 taggctccaa caagtcaagc tctagctgcc cctgctctgt ctgtaaataa ggccaaaatt
     4861 gctctttaac cttttcaaat tctaactgtt ctaaaatctt tttttccata gttcttatta
     4921 tacctaaaaa tcacttaaaa tgtgggacac taaacaaaaa gagaccagag agactctgac
     4981 ctcaaagaat agctgttacc cataattgcc tgagaatgct tgagataaag ggacaatgct
     5041 caaccaagag gcgagacaaa agactgccat gtaggcgccc ttgaataaag ggcatgggaa
     5101 tggtagcaag aacggtcaat gccatgctta aaaacaaaac cgaaaccatc accgccagca
     5161 agccactggc tagcttagcc tcaaagccat caaaataatc caccggcgca aggtgcacca
     5221 agacacccgc caatcgaacc acagcatagc ctactgtaga cagtataaaa aatgctatcc
     5281 ctgcataata aaccttatcc aattcaaaaa tattaatatc cttaaaaaat aaggtagctg
     5341 ctccctcagc aggattagaa taaggcaccc atagagccag cttgcctgcc agagccttat
     5401 agccatgatg ggcaaacaag agcgacacca aggccccaaa acaataaaag gtctgaagga
     5461 taagccctct attgtagcca atgtaaaagc tccaagaaag cagtaacaat ataagcactg
     5521 agagcatcat gacacctcat ctgtatctgc ttgactagcc ttttcctgaa tacctgccag
     5581 tgccttctca cgcagctcga caatctcagc ttcgattttt tcaatctcaa tctctctact
     5641 cagttgggct gacagggtat tgatggtcat caaaatagca acggtttcgt cgtctgcttc
     5701 tggcagacgc tccttgatgg cctgatattt ttcctttgcc acacgatcaa cctcttccat
     5761 aaagaggttg tctttgtccg ttgtcaatgt taatgtcttc tcaccaaatg ttaatttgta
     5821 acgattaata ttcttcatag gctcacccct ttagcattat accctaaaaa tgacttttcg
     5881 taaaattgtg aaattaatct gagattgcat ggaatgattt cccataacag gacattttat
     5941 gttaaaataa tgttcatgga caccttagtt ttcaaaatca attcccaagt cagcagcagc
     6001 ctgatcaagc agctagcacc ataccgcata agcaatgcca atccttacgt tagactggct
     6061 gccaaaaaag atggtgtcac actgatgctg tatacctcag gcaagctggt gctgcaaggc
     6121 agacaggctg caaagctggc tcaagagctt gatctgcaag aaacgcctgc tgatcagaga
     6181 cccgcaccct ccagcgcaca ggatatcccc ttaattggta gtgatgaggt gggaaatggc
     6241 tcttactttg gaggcattgc tgttgttgct agctttgtgc agccagagga gcacgccttg
     6301 ctcagacagc tcggtgtcga tgattctaaa aacctcaatg ataagagtat cgcccagatc
     6361 gctcctgtcc taaaaaagca tattcaacac agggcgcttt tgctatcgcc taaaaaatac
     6421 aatgaaatgg taggtaaggg gaagccctac aacgctgttt ctgtcaaggt tgctcttcat
     6481 aatcaagcga tttttctgct cttaaacgac ggagcaagac cagaaaaaat tgtcattgat
     6541 gccttcacaa gtcaggccaa ttatgacaaa tacctacagc aagaaaaaaa tcactttcgt
     6601 aatcccttga cctttgagga gaaggccgaa ggcaaatatc tggcagttgc tgtcagctct
     6661 atcattgcta gacagctatt tttagacaat cttgacaagc tcagtcaaga tctgggctac
     6721 cggttgccta gtggtgctgg gcgtccatct gatcagattg ccagtcaaat cttagccgcc
     6781 tatggtatgg caggcttaga gcattgcgct aagctgcact ttgcaaacac caaaaaagcc
     6841 caagcgctac taaaaaaaca ataatcttag aaaaataaag gaaaagtcat gaaacaattt
     6901 attaaagaat ggggagcttt tacccttttt atcctacttt ttggactctc acgtttgttc
     6961 ctatggcagc ctgtcaaggt tgatggccac tcaatggacc caaccctagc acatggcgag
     7021 aggctcatta tcttcaacaa ggctaagatt gatcgctttg atattgttgt tgccagtgag
     7081 gaggacgaga acggacagag aaaagagatt gttaagcgtg ttgttggcat gccaggtgat
     7141 aagctgtctt atagaaatga cactctttat atcaacaaca agaaaacaaa agagccttat
     7201 cttgatacct acctgacgag ttttaaaaag gacaaattac aatcaaccta tgcttacagt
     7261 gatctcttcc aagagctggc tgaaaatgct gctgccttta ccgtcaactc cgaaggaaaa
     7321 acagaatttg acatcactgt tccaaagggc gaatatttcc tactgggtga tgaccgcatt
     7381 gtatctcgtg acagccgcga ggtcggctcc tttaaaaagc aggacatcgt tggtgaggtt
     7441 aagttccgct tttggccact caataaaatc aatctcttcc ctagatagca ggcaagctaa
     7501 agctattttc tagcagggct gatataggct ctatgcccac agcagtaaag actcagggca
     7561 gcaatagcct ctatctatat ctgcttatct atccatacca agaggcttga tgtgctatcc
     7621 aagcactcag ctagctttag agaagcagct attgttgacg ttctaaaacc tgccgttgtg
     7681 caggttttcg actatcttgc acagaaaggt accgtcatgg aacacttttt tacaggcact
     7741 gttgaccgaa ttatctttga caatgcgtca aattttttca aaattctatt actggctata
     7801 gaggatactg atagtgattt tgatgaagct gacattgtca ttacaggcac tatggctgag
     7861 atcatagagg gcgaagccta taccttttgg ggtgagctga cccagcaccc aaggtatggt
     7921 cagcagctgc gcctgagccg ctatcaaaag gctaagccca cctcagcagg tctcgttagc
     7981 tatttttcca gtgagcattt caagggcatt gggcaaaaaa cagctgagaa aatcattgcc
     8041 ctttacggta ataatcctat tgatgagatt ttaaaaaatc ccagtcggct taatgagatc
     8101 tctagccttt ctaaggctaa tcgtgaagcc tttgtggcaa agcttaaagc caattatggc
     8161 actgagcagg tgattgctgc cttggctgat ctaggactgg ccaatcgctt tgcctttcag
     8221 ctatttgaca aatacaagga agaggctgtt catatcgtca aggacaatcc ttatcaactc
     8281 attgaggaca ttcaaggctt tggctttaag ctggctgata gcttagctga acagctagga
     8341 attgagagtg cctctcccaa gcgctttcgt gcggctctgc tgcattgcct gttggagcaa
     8401 tccatcaagc gaggcgacac ctatatccag gcacgtgagc ttttggcgct gaccattagc
     8461 ctattagagg acacaaggcc agtcgaatgc gacccagcta ttgtcgctaa tcagctaacc
     8521 cagctcatcg acgagggcaa ggttatgact attggcacgc gtgtttttga cagcagcctt
     8581 tattatgccg aagacggcat tcaaaagcat ctgacacgct tactacagca gcctctgact
     8641 aaggagccta gtcaagatac cattgaccaa gaaatccaag ccatacaaga ggagcttgct
     8701 ataacctatg acaagatcca aaagcaggcc atcagccagg cactgaccag caaggttttc
     8761 attctaacag gaggcccagg cacaggaaag acaaccgtta tcaggggcat tttacaggcc
     8821 tatgccagcc tgtaccagat tgacctgaaa caaaaggata ttcccattat cctagcagct
     8881 ccaactggtc gagccgctcg tcgtatgaac gaattaaccg gtctagcaag cgcaactatt
     8941 caccgccatc ttgggttaaa cggagacaat gattaccaag caatggagga ttatttagac
     9001 tgtgatttgc tgattgttga tgaattttcc atggttgata cctggctggc caatcagcta
     9061 ttaacagcca tcaattctaa tacccagctg atcatcgtag gagatagcga ccagctgcct
     9121 tctgtcggtc ctggacaggt actagctgac ttgctaaagg ttgatcggat ccctcacatt
     9181 acccttgaca agatttttcg ccaatcagag gagtcaacca ttgttgattt agccaaccac
     9241 atacgccaag gcattcttgc tcctgatttt tgtcagaaaa aggctgatcg ctcctacttt
     9301 gaagcgcaag cgccattcat tcccggcatg atgacaaaga tcgtacaggc tgccctaaaa
     9361 agtggcatcc cagctgagga aattcaaatc ctagccccta tgtacaaagg actagcaggc
     9421 atcaacagcc tcaaccagct catgcaaaac ctcctgaatc ctctagctaa tcagacagaa
     9481 tttctcttta acgagacggc ctttcgtaag ggagacaagg tacttcacct tgtcaatgac
     9541 gctcagctta atgtcttcaa tggtgatatt ggctatatca cagacctcat tccagccaaa
     9601 tataccgaat ccaagcagga cgaaatcatc atggactttg atggcaccga gatcgtctac
     9661 ccaagaaatg aatggttaaa aatcaccctt gcctatgcca tgagcattca caaatctcaa
     9721 ggcagtgaat ttcaggtggt aatcctgcct gtcacccgtc agagtggtcg acttctgcaa
     9781 agaaacctca tctacactgc catcaccaga tcaaaaagca agctcatcat gctcggagaa
     9841 atagccgcct ttgaagaggc aatcaaaaaa gaaggtgaca agcgacacac ctatctcgta
     9901 caaaggcttc aagtggctga agctgatgac catacagcag ctgcttcagt aaaggaatca
     9961 aatcagtcta gcctatctgt aatgccagct accagcccac aaaaggaaca agagcagcct
    10021 ccttatctgc tcacccctca taatttccta gctatagacc ccatgattgg tctaaccgaa
    10081 gatgatatgt taaccttttt taagaaaaaa tcataatata ttaaaaaagt aaggcacaat
    10141 ccttattcct atgctataat atccatgtat catcttaaaa gtacaataac ataacattca
    10201 aggagactta tatgatttca tacgaacaag tacgacaagc actcagaaca tcaactatta
    10261 cgatcattat catcaatgct atcagcatgg ttatcacctt gtttggactt gctggcattt
    10321 tctttttgaa gtctcaattg gataaacctg aatttcgtgc acaattttca gctgagcagc
    10381 taaggctatt tgaggttggc atatcaccct ttactatttt tatgtcagtg attagccttg
    10441 gattggttgt tttgaccact gtgctttgtg gctttaacct ctcaaaaatc aaacaaggtt
    10501 ccactgtcag ctatgttcct tacattatag ggattgtgct ctatcttatt agtatcgtaa
    10561 gccaactatt tagccaaatt gagcctgtct caatgatcat tgtcctagct gagcttgcgc
    10621 tttacggctt tgccttttac aaggctaaaa cccttaatga aaaagacaag gacaatcccc
    10681 aaagcattga agaataagca ggccataaag gtatgataac aagacttcct gtctgccttc
    10741 aaatatggct ctttgtcagc ccactacggt tgacaaagag ccttttttaa ccactaaaaa
    10801 agcaagagga aaattgataa tgtcctcttg ctttttttgt tagttgaatg acaggtccaa
    10861 caaaatatct gtcactttat cctttagtcc ggtcattgtg actcccaata agcggattcc
    10921 tgcctgatgc tcctccaggc tatcaaaaag ctctctagcc acctgatcaa tgatcctagc
    10981 atctcttgtt aactcaggta ggctaacccg cttggtcaag gtcgtaaagt cagcataccg
    11041 aaccttcaaa acaatgatcc ttcctagttt tttattcgcc tcaagcaaat cagcgacccg
    11101 tcttgcatgt ttagaaagct ctgccttaat atcagcctcc tggtagagga gcttagcata
    11161 ggtacgctca ctgctgatgg atttgcgcat acgattaggc ttgactggag aatgactaat
    11221 gcctctggcc tttcgataaa gctcatagcc aaagcgtcca aactgatcaa tcagggtcat
    11281 ctcaggaaca cgcaaaagat cctgcccagt gtaaatcccc atctcatgca gcctttcaac
    11341 tgttcgctta ccaacgccat gaaacttttc aatcggaagc ttttctaaga atggcagagc
    11401 atcatcagga agtactaggg tcagaccatg tggcttttca aaatcactag ctagcttggc
    11461 taaaaatttg ttataagaaa caccagcaga gcaggtcaac tgcaggctat tccaaatatc
    11521 atgctgaatc agtcttgcaa tctttaaggc agacttgatg cccagcttat tggttgtcac
    11581 atctaaataa gcctcatcaa tagacacagg ctccacctga tccgtataac gcttgaaaat
    11641 ctctctgata tcatagccaa tcctacggta cttagcatga tctccagaga taaaaatagc
    11701 ctgaggacaa cgctcgtagg cctcctttga gctcattgca gagtgaatgc caaaccttct
    11761 tgcctcgtag ttacaggttg atacaacgcc ccgtccacca ctttctctag ggttcttgcc
    11821 gatcaccacc ggcttgccct ttaattcggg attatctctt tcttccaccg cagcaaaaaa
    11881 agcatccatg tcaatgtgta taatcttgcg tgaggtgtca ttaatcagcg gaaaaataag
    11941 cataggtccc tccctcctac attatactcc tttaggcttt taaagccaag gcagaggatt
    12001 gtatgacagt tttcaactgt ttcagcaaac tgtaatataa aagaatcttg tatttgtcaa
    12061 gatttttgct tgggaaatcg tttcccctat ggtaaactta gattgtaaat gtaacagatt
    12121 ggacttgtta ctagatttta aggagaaact tatggcaact gttaaaacta acgcagatgt
    12181 ttttgaaaaa gcttgggaag gctttaaggg aactgactgg aaggaaaaag cgagtatatc
    12241 tcgttttgta caggctaact atacacctta tgacggtgat gaatcattcc tagcaggtgt
    12301 tactgagcgt tcattgcaca tcaaaaaggt cattgaggag actaaagctc actacgaagc
    12361 aacacgcttc ccatacgata ctcgtccaac ctcaattgct gacattcctg ccggatttat
    12421 tgacaaggat aaggaattaa tctttggtat ccaaaacgat gagctattca aattgaactt
    12481 catgccaaag ggtggtatcc gtatggcgga aacaactctg aaggaaaacg gctatgagcc
    12541 agatcctgct gtacatgaga ttttcactaa gcatgtgaca acggttaatg acggtatttt
    12601 ccgcgcttac acgtcaaaca ttcgtcgtgc gcgccatgcc cacactgtaa ctggtctgcc
    12661 agatgcttac tcacgtggtc gtatcatcgg tgtttacgca cgtcttgccc tctacggagc
    12721 agattacttg atgcaagaaa aggtcaacga ctggaatgcc atcactgaga tcgacgaaga
    12781 atcaatccgt cttcgcgaag aaatcaacct gcaataccaa gcacttggcg aagtggttaa
    12841 gttaggtgat ctttacggtg ttgacgttcg tcgtcctgct gaaaacgtca aagaagctat
    12901 ccaatgggtt aacattgcct ttatggctgt ttgccgcgtg atcaatggtg ctgctacttc
    12961 tcttggacgt gtcccaatcg ttcttgacat ctttgctgag cgtgaccttg cacgtggaac
    13021 cttcaccgaa tcagaaattc aagaattcgt tgatgatttt gtcctcaagc ttcgtaccgt
    13081 taagtttgct cgtacaaagg cttatgacgc tctttattca ggtgacccaa ccttcatcac
    13141 aacctctatg gctggtatgg gtaatgacgg tcgtcaccgc gttacaaaga tggactaccg
    13201 cttcttaaac acacttgaca atattggtaa ctctccagag ccaaacctaa ccgttctttg
    13261 gactgataag ttaccatatg ctttccgtcg ctactgtatg cacatgagtc acaagcactc
    13321 ttcaatccaa tatgagggtg tgacaacaat ggctaaggac ggctacggtg aaatgtcatg
    13381 tatctcatgc tgtgtgtcac cacttgaccc agaaaatgaa gagcaacgtc ataacattca
    13441 gtacttcggt gctcgtgtga acgtgcttaa agcccttctt actggactta acggtggtta
    13501 cgatgatgtg cacaaggact acaaggtatt tgacatcgac cctgttactg atgatgtcct
    13561 tgactttgat actgttaagg ctaactttga aaaatcactt gattggttga ctgatactta
    13621 cgtagatgcg cttaatatca ttcactacat gactgacaag tacaactacg aagctgttca
    13681 aatggcattc ttaccatcac atcaacgtgc taacatggga tttggtatct gtggcttcgc
    13741 aaatactgtt gacaccctat cagctattaa atatgcgact gttaagccaa ttcgtgacga
    13801 agatggttac atctatgact acgaaacaat cggcgactac ccacgctggg gtgaggacga
    13861 tcctcgctca aacgaattag ctgagtggtt gattgaggct tacactacac gtctacgcag
    13921 ccacaagctt tataagaacg ctgaagcaac tgtgtcactg cttaccatca cttcaaacgt
    13981 tgcttactct aagcaaactg gtaactctcc ggttcaccgc ggtgtttacc tcaacgaaga
    14041 tggtacaact aacctatcac aacttgaatt cttctcacca ggtgctaacc catctaacaa
    14101 ggctaagggt ggctggctgc aaaacttgaa ctcacttgca agccttgact tctcatatgc
    14161 cgcagatggt atctcactaa caactcaagt atcacctcgc gcgcttggta agacacatga
    14221 cgaacaggtt gaaaaccttg ttactatcct tgatggttac tttgaaaatg gtggtcaaca
    14281 cgttaaccta aacgttatgg acttaaatga cgtttacgat aaaattatgg ctggtgaaga
    14341 cgttatcgtc cgtatctctg gatactgtgt caataccaaa taccttacac cagaacaaaa
    14401 aactgaatta actcaacgtg tcttccacga agtgctttca atggacgatg ccgctgaagc
    14461 tatttcagga aaataagcta atcttagcta gctaagagcc tgtctgttga caggttcttt
    14521 ttttatcaca catgcaatag gtacagctgt cctcagcagc tgaataacca gcagagctgg
    14581 ttgaaactac tagcaagcct atcattatca ttgtgaaaat cagacgatta accttttcat
    14641 taaaaaaaaa aaaacgaaac tacggagaaa agctgatgag gagctcttta aggctatcag
    14701 tcaacatgtt aaactcttct taggaagcgt taacaataac taactgctaa gctaagcaat
    14761 tatctattaa ggagaataac aatgaaacga ctaaaaacac tatgcttgtt agctactgct
    14821 ataaccctaa ccctagctcc tatcagcaca agccagacaa caacacagac cgtatatgct
    14881 agtgaaactc atcaaaatct ttgtacgaac actggtaacg gatggtttaa atgtcccgat
    14941 ggacatggag ggtggacttg gcattttgac gaaaatcata agtcaaatca gcagtccttt
    15001 ttgggaggat tgttgggctt tgctttgtct ctatggggag ctattattag actcttttaa
    15061 gctctagctt aactaatcct caaacaacaa aaataagctc ttagagaact aagctctaag
    15121 ggctttttgc tgttctgata agtaaaaacc aagagacaag gacatcaaaa acaagcaggc
    15181 ctatcagata taccacctga taggcccact tgtgctctca ttcttatcta ggactatttc
    15241 tgtcaaaggt cctatgaata gcatcccgaa gctgtcgtct ctctttgatc cacaaggccc
    15301 tatcatcctt gtcataggtt ctattggtga gaaaaatcgc tgcctgctgc tcctttttat
    15361 tgagcatgat aaaaggccct gtatagcctg tatgactaat ccaatcaccc tctaggctcc
    15421 aacccaaaga cctgggcttt tcctgtctgc tatagctttg aaaaagtcta tccgaaaagc
    15481 tttccttcag gtaatgctca ataaaccgct ctaaatccct gatggttgaa aaaagccctg
    15541 ctgagcctgc atggtttccc aagaccttag ccttgggatc atgtacctct ccatcaagca
    15601 cccctttgac cgttggaact gcttctggcc ttgggccaaa ggaggtctca gtcattccaa
    15661 agggagtaaa aaccatctcc tgaaaaagct catcaagaga ctttccatga aggtgctcta
    15721 gcatgaagcc aagcaataaa aaattcacat ctgtgtaatg aaaggtctta tcgtccttga
    15781 cctgaagctg gtgcatcgct gctcttaatt gctgggcatt gagctgatct cgattgggaa
    15841 tataagggtc aagtccacta gtatgggtga gtagctgtcg cagtgtaacc tccagctttt
    15901 gagcgtcagg ataataatgc cttaaaggag tatcaagagc caaggcacca ctattgatca
    15961 tggctataca gacagtcgct actccgacaa ccttagagac actggctaaa tcataaacca
    16021 agcctttggt aacaggtctt tgaccatcaa gggtaccgat ataatgctcc tgccaaccgc
    16081 cacagcgaaa aagggctaag ctagccccat gatataagcc ttcctgaatc tgctggctta
    16141 ccttttctat gacttctaat gtcatttgac aaaccaaatt tcgatctgac ttgggtctga
    16201 aagaacaagc acccttgcct ttttatctaa ataaacctga caccctttgt cctcaaggta
    16261 ggtctttaga gcaagcaagt catagctatc tgacacctga aattctaaaa tctccaaatc
    16321 ccatgtgaca tgcgggacaa tcgtcaaatc ttgaccagcc tccctattaa actcaagcgt
    16381 gaccggcagg caatcaccaa aaatagactg ataaaaagct ctggattgct cgtcatctaa
    16441 aacatttaag acaatcagat caaagctaaa ctgactcagc cccctaaagt cagcttcctt
    16501 gtcaattgca ggaacatcat cgacaatgtc aagctccttg atatcgtcct ctgcatggag
    16561 taagaagcga tctccctctg gtgaggtgac ttcaaaggca tagccttttt ttcccttgaa
    16621 aatcaaatca tagtcaacgc catgagctag gagctgctca atgtccttag gagcagttgt
    16681 tttgataaca attgtattta ctttcttagg gccatctaca acgcgtgttc ttgctgctgg
    16741 agattcttca attacaaagc gttcttgtcc ttggccccaa gatgaaaaaa ttgatatcgc
    16801 gttttcctct gacactagcc ttaagcctag atttttttgg taaaaggcaa tattaaggtc
    16861 gcgattgtta acacgtaata ctggggtttt aaagacaata ttgtcaaata aagtcatata
    16921 ttcctcctaa tcctctgcta ttatagacaa aattccaatt tttgacaaga aattatatgc
    16981 tttttaaccg cctgtcacgc gctaccaagg caatatagca ctcacagcca tcaccagact
    17041 tactaggtcc aatcttcctt cgtgcgctct atcacaagca gctttcctta gcgtaactca
    17101 tgcacatatt ggtaaatgcg actttttcaa aatagcacat gaagtacccc tttaatttga
    17161 cttttcctta accaaaagcg agaacctttt ttagttctca cagtagcaat cacactcttg
    17221 aaatgtgatt tcgctctcct caataacaga tgataactga aattgcccgg attttcttat
    17281 ccacgcgcaa cttcaaaagc accttatctt cagcattagt aaggatacta ccagcttagc
    17341 tcagaccaga ttcagctggc tcttgctggc aagcttttat cacaaaaaag aaggcctaag
    17401 ccttcttttt tacttgatat aaaggaattt gaatgctgct actgctgcta ctgctgctag
    17461 cactggggca gcaaccggta cccatgagta ccaccatttt gaatccccct tggcttgtcc
    17521 aaggactgat tttggtaaga aatggtgaac caaacgaggg cctaagtcac gcgctgggtt
    17581 gagcgctgga ccagtaggac caccaagaga ggtcacaaga gtcatcacca agaaaccaat
    17641 ccccaagtga gctactgcaa gtgagcctgt cacgtaagga gagatttgcg ttgcagctgt
    17701 tgtttggtca tagccagcct ctaccagctt accaacaagc tccacaccaa agtaattctt
    17761 ggttaaggcc attgcgccaa aaaagaggac aaaggaacca acaaactcgt tcaaaaagcc
    17821 attaatgtag gctgccttac ggctgccctt gtcaccatca tcaactgctg aaatcgttga
    17881 gaaggatccc aaaatattgt tagggttgtc tgtctgcaca aaataaggct tgtacaccgc
    17941 aacaaccact aattggccaa acatagcccc tagcaattga gcaagaacat attgtaaaac
    18001 gtgtgcccaa gggaacaagc ctgaaactgc caagccaaag gtaaaagctg ggttaatgtg
    18061 atttccagaa acgttaccaa acataagtgc cggcatcatc acaccgaggc catagccaaa
    18121 ggcaatcaca agccagcctg agcggttacc ctttgttccc tttaagtcaa cattggcaac
    18181 tgctccattt cccaaaataa tcaaaaatgc agtggcaata aactctgtga tgtatttcac
    18241 agtccatgtt atttccatat tctctagttt cctccaaatg ataagtataa cagataccat
    18301 tttatcaggg atactagttc ttgtaaagcc tattgtaaga tattgcctgc ttaatatgtt
    18361 tacagtgttt tttcacaatt acggacaact aataagtctt ttttagcatg tcgcaggata
    18421 tactctgagg tcgatccaat cagcagacgc tcaaaggtat ttaagccagt tgctcctacc
    18481 atgatcaaat cagcctgctc cttttcaggt atgtcactag ctaagagctt tttagggttg
    18541 cctctttcga tgattttttt aatgctgcta acgcctctgc ctctagccat tttctcgtaa
    18601 tagcgcaaca cctccttggc atgctcctct tgtgtgtcaa agacataatc actaaccatt
    18661 gcatcaccct gataggcctt aacatcaata acatgagcca gcagtaagac cgcatcattg
    18721 cgaagggcaa cattaatggc cttctcaaca gctaattctg attcgtaaga gccgtccacc
    18781 gcagccagaa tccgtttata tttgcttatc atctttgtct cctttcgttg attagccttt
    18841 atcaatagcc tttgcttgtg tctttaggaa atacatgact gcgcaggcag ctggaatgag
    18901 ccctgccagc cagaacaatt gatgaaagga ctgcacacca gacccaagaa gcatatcctt
    18961 gatgagtccc aacagataag gtcccgcacc caagcccaaa tctagcccaa tcatataagt
    19021 agacatagcg gtattaaagc gatgctcctc aacccccttg atggaggctg cctgtccgca
    19081 ggacataaag gttccatagc caaagcctat caaagcaccc gaaagcagat agggaaggct
    19141 gcttgtcaca ctaccaagca ggaaaagccc tagcgccaaa aagagatagc tgggataaag
    19201 aacccactgc tcccccttaa cgtccatcaa gcgtcccata gcaggtcgtg tgatcgtaat
    19261 gatcaaggca tataccacaa agaaataggc tcccaccgtc gtcaaatgaa tgtctgttgt
    19321 gtataatttt tgaaagccta gcacagaagc ataggcaatc cccatcaaaa aggcaatcaa
    19381 ggtgataaat aaggcctttc gctcaataaa gctatcaact gtccaggatt ttgtttttgc
    19441 cagctgctct gagttgaggg caatatctgt cacaggaaag gcaaaggccc ctagcacaac
    19501 tactgcgatc aacacactgc acaaaataat aatcatccga aaatcaatgt gcaaattatc
    19561 cagcataaag gtcccaacaa aaggaccaat cgccgccgct aggcttgttg atagaccata
    19621 aaaattaatc ccctctccgc gcttgctagc tggaatatag gcagtcacaa tggtattggt
    19681 tgctgttgag acaacaccat agccaaagcc attaaacaag cgcacaaaat acatcatgcc
    19741 aatcgttggc atgaaaaagt aggctagcgt tgttaggaga taaaaaatgg cgcctcctct
    19801 tagcactaag cgtcggccaa aaacctccaa ttgcttgcca aaaatcagtc gagccagcag
    19861 ggttcctagg atataaatcc ccgtcgccag acctgcctca ctggtcttag ctcctaattc
    19921 cttagtcgca acaaaggcaa tgatcaccgt aaacaagtaa tagaccatat acacaataaa
    19981 atttaatact gtgatcccta taaaatgctt gttaaataat ttgtcttcca ctgaaaatga
    20041 gctcctccct atttcattaa cattttacaa aaaaatcaga taatgcccca tttcaatggt
    20101 ataatatagg tgatactatt aaacgacatt agcaaatgct aagcattgct gcagcaacaa
    20161 attatataat gataccagaa acacctctag gagaaaagcg tgaaccatca aatcttacag
    20221 cgttatattg acagtcataa ctttcctatt atcgaaaagg gctaccacaa atacctgacc
    20281 tttgaaagct tagaggagga ttttacgtat atcctaaagg agggcattgt caagcaaagc
    20341 gttctgtcaa aatatggcat ggaatttaac ctcaggtacg tcacaggcct tgagatcacc
    20401 tctgtgctta atactggcta ttccaaggac atgagagagc cctacaatgt tcgcatcgaa
    20461 tctgagactg ccagctttta taaggttcgt cattccacct ttttaaggga tattagcgag
    20521 gatatcgagc tgcagggcta tgtcaaggac ttttatcact accgcctcca aaaatcaatg
    20581 aaaaaaatgc agtgtatgct gacaaatggc cgtatcggcg ctatctctac tcagatttac
    20641 gatttaatga ccctttttgg acgccccttg gctaatggcc atatccttat tgattttatc
    20701 atcacaaatg aggagctggg caaattctgt ggcatttcga ctgccagcag tgtcagtcgt
    20761 ctcctaaagc agctcaaaaa agagggcatt attcaaatca atgaccagca tatcatcatt
    20821 accaatttag agaagctaaa ggataatatt gttttttaac gatttagaaa ggacgtccca
    20881 tgcgctataa tcaattgtct tacattccca ccagtctaga aacagctgta gctgagcttc
    20941 aggccctggg ctttgctgtc cagcaagagc aagcacccaa ggagaacttc gctattttcc
    21001 ttagaaagct attttttcat tttcaggata ccgattatcc cttgagccat atgattgcaa
    21061 gcaaggatct cgacctattg acctttttaa catctgatgc aacactgaca aaagaggttt
    21121 ttgatttagt ggccttacag gtccttggct ttattcctgc tgttgacttt accgatgcac
    21181 aggactttat acaaaagatt ggctttccga ttgtttttga cagccagcaa ttactactca
    21241 atttacatca gctgcttgca acccggcaga agtccggtgt gaccttgatt gatagccttg
    21301 ttagtcaggg cttgcttcct atggataatt gctaccacta cttcaacgga aaagccctag
    21361 caacctttga taccaccagc ctcattcgcg aggtggtcta tgtcgaagcg ccacttgata
    21421 ccgatcaaga cggacagctt gacctcatca aggtcaacat tatccgcccc aaggccagca
    21481 ctgctatccc aagcatgatg acagccagcc cttatcacca agggattaac gagaccgcca
    21541 acgataaaaa gctccatcgc atggaaggtg agcttagccc taaggctcct cgtaggatta
    21601 ccgttgagcc aactgatttt cagccgcttg ccaccaagcc ctcaaggctt cctgtcaatg
    21661 agtgccaaga gaccttcagc catatcagct cctacacact aaatgattat tttctagcgc
    21721 gtggctttgc caatctctat gtctcaggag tgggaacagc aggctcaact ggctttatga
    21781 caagtggtga ctacgcccag atcgaaagct ttaaggctgt tatcgattgg ctaaatggca
    21841 gagctactgc ttacacgagc cacaagcgtg actatcaaat caaggctgat tggtcaaatg
    21901 gcttagtcgc aacaactgga aaatcctatc ttggtaccat gtcaacagga ctggctacaa
    21961 caggtgttga tggcttagca gtcatcattg ctgaagctgc catttcttct tggtacgatt
    22021 attatcgtga aaatgggctg gtatgcagtc ctggtggcta cccaggagag gatctcgatg
    22081 tgctgacaga gctcacctac tcgcgtaacc tgctgccagg tgattactta cgtcacaacg
    22141 accattatca acagctgctg agccaacaat ctcaagctct cgagcgccaa tcaggcaact
    22201 acaatcaatt ttggcatgac cgcaactacc tgccacaggc tgatcgcatc aagtgtgagg
    22261 tcgtctacac gcatggccta caggactgga atgtgaagcc tagacaggtc tacaatatct
    22321 tcaatgccct gcctgatagc cttggaaagc accttttcct acatcatggt gagcatgtct
    22381 acatgcacaa ctggcagtca attgattttc gtgaggccat gaatgccctg ctctgtcaaa
    22441 aaatgctagg acaaaataat ggctttaccc taccaacaat catctggcag gataaccaaa
    22501 aagaacaaac ctggaaagag ctaacagcct ttggcggtca cagcaagcgt cagattgccc
    22561 taggcgatga tcatgtctta attgacaatc actatggcga agaggacttt aagcgctata
    22621 gcaaggattt tcgtgccttt aaagctgagc tttttgaagg caaggcaaat caagcagtca
    22681 ttgatattct gttagaagag gatctaccaa tcaacgggca agcctgcctt aagcttaagc
    22741 taaaatcaag tgaaaacaag gggattttgg ctgcacagct cctagattat ggcaagaaaa
    22801 aacgctttgc tgatatacct gctattcttg agctagacag cattgacaac gggcagcagt
    22861 ttgcacgtga agcgctcaag gagcttccct tcaaggacag cccataccgc gttgtcacca
    22921 agggtgtcct aaacctacag caccgcagcg acctattgac cattgaggat attccaaatg
    22981 accaatggat gaccatcacc ttccacttgc agccaaccat ctatcatatg gccaagggag
    23041 acaccctaag agtcgttctt tacacgactg attttgagca tacaatccgc gacaatagca
    23101 actatgccct aaccctagat ttggagcaat cctatctcct aatccctact gatgaggagg
    23161 aataaatcaa agcgcatcaa aaaagcctga gatcacaatg agctgcaccc caatcgttag
    23221 atcctttgtc taactgttgg agtacagctc aaagctctag gcttttttaa ctattttgaa
    23281 acctttttac cagcctcagc accagaatgc aggctgtaga cggactcgat atgaatcaag
    23341 cctgctgcct ttggtgcgcc catcttgcct tctgcccatt ccttggcagc ctcaaagaca
    23401 ggaccctctg taatgatttc cgcacgccct acaaagcgat aaccacgcaa ttgctcgcga
    23461 ttgacataag cgacctcaat tttaccatta gcctgaatat tagagcaggt ttggccgcca
    23521 gtattttcat tataaaccaa ggtttcatcg tctaacagtc tcatcgaacg cttagggcca
    23581 atattaggat taccctcatt atctacagtt actaccattg ctaattgctc agcaatcatt
    23641 tctttcattt cttctgttaa catataatct cctcttaatc gtttctatag tcagctgact
    23701 acgctttgat tatagcacag ttaagcagaa aagccgacaa aaataggtta gcttaaaaaa
    23761 gttttacagt ttacttaaga ttagaatgat tctcgctatc tagccatcac ccttgatcac
    23821 agtaaaaagg cgattagcaa gcaagcactc tttatttcat aaaatccgaa tcgtcgccca
    23881 aaaaaaatat catcaactga tatggtcaat gcctctgcaa tacctcttaa tttttcatac
    23941 ttagctcgcc taagcttttg cacatccttt tcatatctgg ctagtgtcct aacagaaatc
    24001 ccagttaacg ctgacagttc cttttgggtc tttttttgag caatcctcaa ttcctttaac
    24061 gttgcttttg acaatatttt ccctccgcct ctcatctcag gtaatattaa tgacagatga
    24121 caagtttatt atagacttcg gtttttatga agtcaagtct tttatcgcac tttccccact
    24181 tctttttcta aatcttttga tttagcttga tttgtggtat catatcctat atagaaataa
    24241 aggagaatgg aaatgtccga aaagaaaaca ttttttgcaa ctaatttaaa atatcttcgg
    24301 ctaaaaaaga atatggaaca attagaactt gctaaccttt taggacgaaa aagctcttcc
    24361 tcaatcagcg aatgagaaag aggaaagtac actccaaaat ctggtctcct gagtgacatt
    24421 gctgccatct ttgatgtcag cctgacagac ctcatggaaa aggatttaac actggaaaat
    24481 aagggagtga cttatcagct tccccaaaga gatttagtaa tgatttcaga gcagctatct
    24541 gaaaacaatt ataacaaatg gctggatttt ggtcaggatc tcttatctca tcaggataaa
    24601 gaagaaaatc acaagccaag caaataaaga gcctcacacg tcttattctc atcaagtttc
    24661 gaaaaatcac ctaccactca agcacacaaa aagccttggc agggcttcta agcataagaa
    24721 agctgtatca tatcaatacc tcagggacca tgatatgata cagctttttg tatctcactt
    24781 ttagacaagg tagccacata aagcttgcag atgacctacc tctgtattag ctaccacaac
    24841 caacagctag ctagactggc aggccctcta taagcctcag cggattatct aagcactccc
    24901 aacagctcca acaaaataaa gacataacca ataccattat ttaagatatg ggctactgtt
    24961 gaaaaataga tattcttctt ccaaacataa actaagccga gcaaaagtcc cagtccacca
    25021 tacacaacga tggaagatag ctcgctgaag gaatagatat gaaccaagcc aaatagcaat
    25081 gatgatccca acaatcgagc cagcagcata cctgtgcctg attggccctc accgattaaa
    25141 atcttgcgga aaataagctc ctcattgaag ggaccaataa tactcaccac cagaataaag
    25201 atcactgtct cgaagccctc actagcatta tagcgattag ctaaaacagc tgcattgctg
    25261 ctctcttcta aaggaaggct actgagcaaa atatttgcaa cataaagcac tgcaaaaatg
    25321 accaagaccc acaaggtatt tttgacccat tttgttgaaa actgccgcca gtccctctga
    25381 taatctgctc gataaagcca acagatccca agtgcaaaaa tcagcagatg tctcccgtaa
    25441 aataaaaagg tattcaataa aggcggaagc tcaatcacat tgctaacttg tctataaaga
    25501 tacacagcaa tgatatatag catgaccagt acagctgcac gatgacgttt gatggtatcc
    25561 aattactctt cctcaattct aataattgtc agattagcta ggctatattg ccatcagcta
    25621 atcttgatct taaatgtgac taatttacaa gcactcaact tttgaatcgg taaagctgac
    25681 agacagccct accctagctt caataaagct atcttccaat agtccttgcg ctcatcagaa
    25741 ctgtcaaagg cctgacccag ctgagtcaac agacttatcc agtcaacatc acacagaaca
    25801 agaccatctt accatatccc tgccaactat aaaagcccct aacctgacct atttgactac
    25861 taacagcaaa aaagcagctt aaaaacacca atcagacgcc accaaggact cttgatcagc
    25921 gcagctcgca cagacacctg aaaaatgaca gacaagcctc ttaaaagcac ctcagcaagc
    25981 tgagccaacc cttcacagaa tagacaaaca acaagagcta agtcaagacc tcaagctagc
    26041 agattacagg cagagacgct tgcaaggctt acccagcaaa aagcaacaga ctgataaagg
    26101 attcacacca cacagccaca agtcaagcag ctagcccaaa caaagcactg ctcaccaaat
    26161 cctactatgc tttctggtag cccttatcca ttcaaaatcg tatccaaggc ttcttgatat
    26221 tgcttgtctc gcaattctct gatcacctgt gataaatact ctgcctgata catcacaaag
    26281 tcaaaattga aatccagaat tttggtgttc tcattcaatg acagcctctc ctcgataaaa
    26341 gcagtcatct cagctgttgt cacaatcaag tcaaaatcag ttctccaagg caattcagcc
    26401 tctgacaaaa tattaaaacg atagaccttt gcaacacaag gactcacctg ttgcatgacc
    26461 aagctatata aaatatcaat gtttttcttg ttgatttcga tcactgctat ggctaaaggt
    26521 ggcagacctt ctctaacaag ctgttccagt cgcgtgcaaa gcaaatgcaa attagagcct
    26581 gtcagccgac caacaccaga aacccgctct gcccagctat taatcatcag ctcgatacga
    26641 ttggccaaga gcttactgcc ttgatattcc tccgcataat aatatttttg cgggataaag
    26701 agcgacaaat caaacaaggt cttacgaaaa taaggaatca aggtctgaat acaagccttg
    26761 tcaaaggcga tatagtggcc aaacaattga cgcagctcac ccagcagctc ttggtaagca
    26821 ggatcctcct gaatgatcgt caataaggcc gaagaatcct cctcagacca ttgtgtgatc
    26881 gaaaaagagt tgttaaccgt caaataaacg agaaaaatat aatcaatctc gctactggga
    26941 aagtccatat caagcaacaa tttcccctca cgcttgaaaa agtcctccaa atacccataa
    27001 agcgccaaag actttaagcg tttaaaaatc ccctcctgag gaatcgcaac gtcaaactct
    27061 ccacgcttcc aagatagcga caagagcaca tcaaaaaagc gaaacttctt atccagtaac
    27121 gggtgaggcg tttgttgctt tttgatcgaa aagataaagt catgcacaat atccagatca
    27181 tggtcagtca gctcatagat gacaatcccg tacttatcat gcaataaagc aatcaaatag
    27241 cggatacgcc actcctcacc aacaacacta ttatcctcta aggccaagcc gcactcctca
    27301 acaaagggct tcatgtgctg aatcagccga taagctgacg gtgtggaaat aaaatgctcc
    27361 ctagcaaagc ctgagacaga tttgacctta tagcaaggtg ccttgatcaa gagaaattta
    27421 agaatgtgca gccgtaccga ttggcggtaa atcgtcttca aaaacggttt gccccttttc
    27481 aaaacggtgc agcggacaat ggtgctatcc cactcaaagg cgatatctcc ttggaaaagc
    27541 tcctctaatt ggtggatata gcgctttatg ttagctaggc taaagcccgt cttttgctga
    27601 atggcgtgga aactgatcct ttttttacca agtagtatgg tcagcagcaa agcctgatga
    27661 ttaatcactg gttccaaata ctcttcaagc aaaacacttt ctcctcctta aaccatttcg
    27721 ttagcgtcat tatcataaca atttttacca aaaaagtgat gaaaaatatt taatatcagg
    27781 acgatttttc tgatagcctt tattataaca caaaagctca aggcaggtaa aacgataaag
    27841 aaatcaactt aaaactatga cacagtctca tctcatatga tatagttatt caggtttcct
    27901 aatggaaaac atattaacaa cttaataatg gagagaagaa agttgaaaac aaaatcattt
    27961 agaaaggtac tgacaacgtc agctacctgt attgtgctgg caacaagctt tgccggagga
    28021 accctaagag tctgggcaga gcagctttat tatgggtgga atgatggaac gagacaaagt
    28081 tcgccatatt ttttgtacgt atcgcctaaa aatgctccaa agcgtgaatt aaaagacgag
    28141 tatgttgttt attgctttaa caaaaaattg tattggccag atcaatggga atctatatac
    28201 agcaatttta atgacatcag atctccatat aacgatttac ctgtatatga gaaaaaacta
    28261 ggatatgatg gtatatttaa acaatatgct ccagattaca aaaaagatat tagtgatatc
    28321 gcaagtgctt tggtggcagt tttaagtaat ggatacccca ctaacaagtc acaactatca
    28381 actagctacc atttaaataa tgattcttct agaaaagtta ctcaattagc catttggtat
    28441 tttagtgata gtttaacaaa agaatacctt aaagatacgg gtggttataa cttaaacgat
    28501 atggaaaaaa aagctttaga ttttttaatc agtaaaggag aggattctaa gcttaaatca
    28561 gagcagagta attactcatt ggatatttat gtttatcaaa gtggcgggca tgaccatatg
    28621 aaagattacc aaaatcttct cggctctacc ttaattccta aagaaccgct aaagcctcag
    28681 ctaggtggtt ttagtggaca taatggaaat ggattaagcg gccttgaagg aggatcatca
    28741 ggttcacaag aaactaatga agatggtaag aaaggactta taggtttcca tggaggactc
    28801 tcaggaagcg agggcaaacg agatcctttc caggattgaa gggtgaggct ggtgcacctg
    28861 atacacctca aaagcctaat gacccattgc aaagtcttga aggtggtaac tctcctatcg
    28921 tagaacaaaa ctatggtagt actgagggat atcatggtca atctggcatt cttgaggaaa
    28981 ccgaagacac taacccacct ggtatcattt taggtggctc aggaaatgtc gaaacgagat
    29041 cctcatctga tggggcttgg cggtggtcta gctggcgaat caggagaaac gacacctaaa
    29101 ccaggacaga ctggtggtca tggaccaatc atcgagacaa cagaggacac acaaaaaggc
    29161 atgtctgggc aatctggcgg cactatcgag tcagaaaaca ccaaaaagcc tgaggtcatg
    29221 attggtgggc agggacaaac catcgaaaca acagaggaca cacaaaaagg catgtctggg
    29281 caatctggcg gtactatcga gtcagaagac actaaaaaac ctgaggtcat gattggtggg
    29341 cagggacaaa ccatcgaaac aacagaggac acacaaaaag gcatgtctgg gcaatctggc
    29401 ggtactatcg agtcagaaga cactaaaaaa cctgaggtca tgattggcgg tcagggacaa
    29461 atcatcgact tctctgaaaa cacgcaatca ggtatgtctg gacagtctgg agacactacg
    29521 gtcattgagg ataccaagaa gtctgagata atcattggtg ggcaaggaca aatcatcgac
    29581 ttctctgagg atactcagcc gggtatgtct gggcaatctg gaggcaccac aattgtcgaa
    29641 gacaccaaga agccgacacc taagcctaaa cctgcacctg cgccaattgt taatgacgaa
    29701 aaacctaaca aaggcactca gctcccacag acaaatgata tgaagcaact caccctaagc
    29761 atcatcggtg caatgtcaat gctgcttgtc ctatgtctgt ctctattcaa gcgaccatct
    29821 aaaaaagact aagcaacact gacaagtgat cattattgta cggacgttta caggcgggct
    29881 ttctgccctc ttaaaacacc gtacaacaac aaaacggtct aaatagaaat atccctcaag
    29941 ggttagacaa tcgctctagc ccttggggct ttttttgata cttataatag aagagagcaa
    30001 gcagtgacac tttctttttg ccctatatct gctaacacta gcggtatgtg cagttaccat
    30061 aggctatcaa ctcgtcgtgc aactctagag aaaagctgat acaaaaaaca agcaccagcc
    30121 ttgctgctga tgcttgctcc ggacttactg ataagccttt gtgatgtcct agctttataa
    30181 ccatatgcct attacctaaa ggtctagtct cctaatggtg ggctggctgg taaaagcaag
    30241 gagaaacagc tcccctttcc aagctggctc tcaacagcaa tatccccacc tagttggcga
    30301 gctaactgcc tagcaataga gagccccagc ccatgaccac cagtcttcat attgcgagag
    30361 gcctcaacac gatacaggcg cttgaaaatc aaaggcaggt cctctttttt gatcccttgc
    30421 ccctgatcaa taacatcaat gcgaatggac tgctcctgtt gataagcatg aatcgtcaaa
    30481 gccgtattag cctttgaata tttaagcgca ttgctgacta aattcagcat aatccgagac
    30541 aaagcatcat atcggctgct gatcttaacc acctcttttg ccacctcaat atgaacggag
    30601 cgtttttcct gctctaaggt caattgaaat tcggatagca tgtcaatcaa tagcttttca
    30661 agatagatga tttgaagctg ctgcttgtcg tcttgctttt gatcatttaa gctgaccata
    30721 tgcaattctt caactaattg attcaaacgg ttggtctgtc gtgagatggt gtttagatag
    30781 tgcctttcct cttcccttgg aataacgcca tctaaaatcc cctctacagt tgcttgaata
    30841 gaggtcaagg gtgtcttaat atcgtgcgac agctgagcaa tcatcatgga tttctcatgc
    30901 tcactctcac tcaatgactc aaagctgacc tttagctctg aggacatctg attaaaggct
    30961 tcctctagat ctttaaactc caaaggacac ttgatgagct gaccactatc aaagtttctt
    31021 tcagaaatag cctgtatctt tttctttagc cttttaagcg atgaaaaaac attactcaaa
    31081 aggatcatat tcacaattcc tccggctact gaagcaatta gagctattac taaaatatat
    31141 gaaatatcct caatggtaat gagcatttgg tttaacccaa caatcaggcc tgcaatagta
    31201 atcagcatag acattaaata gccaatgaca atgtacgttc ttaatcgcat gctacccctc
    31261 taatttataa cctagtcccc aaaccgtttt aatggttggt gtttgctcgg tactgtattt
    31321 tgccaagtca ttgcgtaggg aatgaatgtg aacatttaag gtattggtat catctaaata
    31381 ctcctcctcc ca
//
LOCUS       DARYVE010000022        31131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYVE010000022 DARYVE010000000
VERSION     DARYVE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVW25_000911"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVW25_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1378558.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TVW25_000912"
     CDS             complement(1584..2021)
                     /locus_tag="TVW25_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1378559.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TVW25_000913"
     CDS             complement(2008..3234)
                     /locus_tag="TVW25_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1378560.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVW25_000914"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVW25_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1378561.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVW25_000915"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVW25_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1378562.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TVW25_000916"
     CDS             complement(5505..6662)
                     /locus_tag="TVW25_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1378563.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVW25_000917"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVW25_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1378564.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TVW25_000918"
     CDS             complement(7553..8392)
                     /locus_tag="TVW25_000918"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1378565.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TVW25_000919"
     CDS             8708..10276
                     /locus_tag="TVW25_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1378566.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TVW25_000920"
     CDS             10269..11009
                     /locus_tag="TVW25_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1378567.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TVW25_000921"
     CDS             11357..11473
                     /locus_tag="TVW25_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1378568.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TVW25_000922"
     CDS             complement(11997..12887)
                     /locus_tag="TVW25_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1378569.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TVW25_000923"
     CDS             complement(13150..14814)
                     /locus_tag="TVW25_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1378570.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TVW25_000924"
     CDS             complement(14814..15179)
                     /locus_tag="TVW25_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1378571.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TVW25_000925"
     CDS             complement(15331..15519)
                     /locus_tag="TVW25_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1378572.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TVW25_000926"
     CDS             complement(15979..16344)
                     /locus_tag="TVW25_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378573.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TVW25_000927"
     CDS             complement(16934..17815)
                     /locus_tag="TVW25_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1378574.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TVW25_000928"
     tRNA            complement(18018..18103)
                     /locus_tag="TVW25_000928"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TVW25_000929"
     CDS             complement(18158..19084)
                     /locus_tag="TVW25_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1378575.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TVW25_000930"
     CDS             complement(19444..21057)
                     /locus_tag="TVW25_000930"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1378576.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TVW25_000931"
     CDS             complement(21331..21897)
                     /locus_tag="TVW25_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1378577.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TVW25_000932"
     CDS             complement(22164..23447)
                     /locus_tag="TVW25_000932"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1378578.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TVW25_000933"
     CDS             complement(23796..25205)
                     /locus_tag="TVW25_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1378579.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TVW25_000934"
     CDS             25656..26495
                     /locus_tag="TVW25_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1378580.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TVW25_000935"
     CDS             complement(26591..27151)
                     /locus_tag="TVW25_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1378581.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TVW25_000936"
     CDS             complement(27164..27637)
                     /locus_tag="TVW25_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1378582.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TVW25_000937"
     CDS             complement(27643..28392)
                     /locus_tag="TVW25_000937"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1378583.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TVW25_000938"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TVW25_000938"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1378584.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TVW25_000939"
     CDS             29318..30682
                     /locus_tag="TVW25_000939"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1378585.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
BASE COUNT         9264 a         7451 c         5668 g         8748 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat actgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggcgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattggg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa g
//
LOCUS       DARYVE010000023        25833 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYVE010000023 DARYVE010000000
VERSION     DARYVE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25833
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            98..703
                     /locus_tag="TVW25_000940"
     CDS             98..703
                     /locus_tag="TVW25_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1378586.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            1171..3951
                     /locus_tag="TVW25_000941"
     CDS             1171..3951
                     /locus_tag="TVW25_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1378587.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYLDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(4373..4510)
                     /locus_tag="TVW25_000942"
     CDS             complement(4373..4510)
                     /locus_tag="TVW25_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1378588.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      4754..4872
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            4870..5376
                     /locus_tag="TVW25_000943"
     CDS             4870..5376
                     /locus_tag="TVW25_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1378589.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            5473..7431
                     /gene="ligA"
                     /locus_tag="TVW25_000944"
     CDS             5473..7431
                     /gene="ligA"
                     /locus_tag="TVW25_000944"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1378590.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            7444..8466
                     /locus_tag="TVW25_000945"
     CDS             7444..8466
                     /locus_tag="TVW25_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1378591.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            8475..10775
                     /gene="pulA"
                     /locus_tag="TVW25_000946"
     CDS             8475..10775
                     /gene="pulA"
                     /locus_tag="TVW25_000946"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1378592.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            10922..12801
                     /gene="glgB"
                     /locus_tag="TVW25_000947"
                     /pseudo
     CDS             10922..12801
                     /gene="glgB"
                     /locus_tag="TVW25_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            12868..14007
                     /locus_tag="TVW25_000948"
     CDS             12868..14007
                     /locus_tag="TVW25_000948"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1378593.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            13997..15130
                     /gene="glgD"
                     /locus_tag="TVW25_000949"
     CDS             13997..15130
                     /gene="glgD"
                     /locus_tag="TVW25_000949"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1378594.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            15127..16557
                     /gene="glgA"
                     /locus_tag="TVW25_000950"
     CDS             15127..16557
                     /gene="glgA"
                     /locus_tag="TVW25_000950"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1378595.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            16576..18972
                     /locus_tag="TVW25_000951"
     CDS             16576..18972
                     /locus_tag="TVW25_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1378596.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            19314..19511
                     /locus_tag="TVW25_000952"
     CDS             19314..19511
                     /locus_tag="TVW25_000952"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1378597.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            19545..20261
                     /gene="atpB"
                     /locus_tag="TVW25_000953"
     CDS             19545..20261
                     /gene="atpB"
                     /locus_tag="TVW25_000953"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1378598.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            20279..20773
                     /gene="atpF"
                     /locus_tag="TVW25_000954"
     CDS             20279..20773
                     /gene="atpF"
                     /locus_tag="TVW25_000954"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1378599.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            20773..21309
                     /locus_tag="TVW25_000955"
     CDS             20773..21309
                     /locus_tag="TVW25_000955"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1378600.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            21325..22830
                     /locus_tag="TVW25_000956"
     CDS             21325..22830
                     /locus_tag="TVW25_000956"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1378601.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            22848..23723
                     /locus_tag="TVW25_000957"
     CDS             22848..23723
                     /locus_tag="TVW25_000957"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1378602.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            23891..25297
                     /gene="atpD"
                     /locus_tag="TVW25_000958"
     CDS             23891..25297
                     /gene="atpD"
                     /locus_tag="TVW25_000958"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1378603.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            25310..25726
                     /locus_tag="TVW25_000959"
     CDS             25310..25726
                     /locus_tag="TVW25_000959"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1378604.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT         7206 a         5027 c         6188 g         7412 t
ORIGIN      
        1 cttttagttt tgataagcac aatccgctgt tgactgtata aaccgtatat gatacaaaat
       61 aagagcttgt agcagtgaag ccactaactc tagtgctgtg ggctcaacct tgattgatga
      121 atcccttgct tttaatgcgt ttatgaagca gtggcgtatc agtctagctc gttgtggaaa
      181 gcaattaact agagaagaat tactatcctc aatcaatatg ctgacagccg cagggatttg
      241 tgagtttgat ttgctgtggc agcgtcttgc tcctaagggg tgtcagcgtc ccaaatggag
      301 ccatcagctg gagaggctct ttgcggatac aaagccttgt ctacaggtct tgtctgagac
      361 ttatcagctt gggattattg ctaatcaggc aaagggtcta aaagagcgct tagagaggtt
      421 tgggattagt cattattttg cccttatgat atcttcttct gatgtggggc tacaaaagcc
      481 tgatcttgct ctgtttcgct atgcacttga tcaagcaggc gtattagcgc gtgatgctgt
      541 ttatattggg gatcgtgttg acaatgatat tattcctgct aaggcattgg gaatgagagc
      601 tgtcaggatt catcaagggc ttgctgcgtc cagtccagat gataggcttt atcctagtga
      661 tgtccatatt agcaaactta gtgacctgtt agaatgcttt taaccagtct ttagcttgaa
      721 ctagcttttc tttgtggtct ttctgggtga atggcagcaa gctttggagt catgttatgg
      781 ctagaccttg gatctaaggg cgctgagcgt ctcatatgat gaggccgatc aagtagtctc
      841 cttgacaagt agattattgt ttggtgctta taggtggctt taggtgatga ctggttttgc
      901 ctcaactaag gctcgctatt gctatctggg gtatcttctg acttttttaa tgtgctctta
      961 tctggttgga ttagacctgc tccttgcttg aggaaagctg tttttaacgc tgatgagtct
     1021 gggaaatggt gagattggtg ttggctttta ctagtttttt tgcgtttact tgggctaact
     1081 ttatatgaga aaaaaagaaa aatatttatt ttatctgtta tttttgttac aataagcgtg
     1141 taaactaaga tgcattaaaa aggagttttt atgtcgaata agaaattttt tacttatgct
     1201 tcattattgg cattaatcgc tgttcctact gtggttgaag aggtgactgc acagccttca
     1261 gctcagcttg tttatgcaga tgagctaagg ctatcaccaa gtaccgactc atctccagta
     1321 acaaagaccg atgaggctga tcagccagtt gctcaatctg tttctgcgac agaaccagta
     1381 gaggctcttg ttattgcgga taaagaaagc gctttaaatc ctgctgttct agctgatgcc
     1441 gatggaagtc agccgattgc agtggttaga gctggtcaag agggtcagcc ttataccgtt
     1501 actggcaaaa tcatcagtgc tgttaatggc tggggtggtc atggctttta tatccaggac
     1561 agtcagggat caggtcttta catttatcca ggaagtgctt tggggtacgt gactggtgat
     1621 gtggtgcagc tgacaggaac actgactact tacaagggtg agcttcagct taaaacgatt
     1681 acaaagcatc ataagattaa tggcgaatta ccaacaccta ttgctgaggt aaccattccg
     1741 gagctagaaa aagcaagccc gtctaccctg gtgaagcttt caaatgtgac tgttggagac
     1801 atttcatcag ataagcacga aacctcctct tttaaggtca gcgatacagc tggcaatagt
     1861 gttgcggtgc gtcttgataa tcgtacaggt gttaagacct ctgacttact ctctaaaatt
     1921 ggcaagggtg atgtgattaa tctgacagct attcactcaa cctttgatgg gaagctccag
     1981 ctcaagccct ttagccttga gcaatttgag gtagtaaaga aggttgttcg agaagaagag
     2041 gtgactcctc ttggtcgagt ggttaaaatc ggccaaattc aaggtgccag ccacacctca
     2101 ccgctcttga atcaagctgt aacagtaaaa gaggtggtgg tgacctatct tgatgatgca
     2161 actcatttct atgtgcaaga tattaatggt gacaacgata aggcgacctc agacggtatt
     2221 cgtgtctttg ctcaaaatgc tcaggtgcag gctggtgatg tgctgaccat ttccggaaca
     2281 gtggaggagt tctttggcaa aggctacgat gaccgtaagc agacggatct gaccattacg
     2341 caaatcaagg catctaaggt cactaaaaca gggactgctc aggtaccagc tccgcttgtg
     2401 ctaggtaagg atcgtgttgc tccagctaat atcattgata atgatggctt tagtgttttt
     2461 gatccagaag aggacgctat tgatttttgg gaatccttgg agggaatgct tgttgccgtt
     2521 gataatgcca agattttagg gccgatgtct cataaggaaa tttatgtgtt accagggtca
     2581 tcaactcgag tgctgactaa ctcaggtggt attttacttc ctgagacagg ctataataca
     2641 gacctgattc ctgttctctt taaaaaagga aagcaaacca tcaaagctgg tgattcctat
     2701 cagggacgac ttgcaggtcc ggtatcatat agctatggta attataaggt gtttgtcgat
     2761 gacagcagtc gtatgccagt cttggttgat ggtcagctga agcctgaaaa gacacacatc
     2821 aagaaggacc ttagcaagct aagcattgcc tcatacaaca ttgaaaactt ctcagcaaac
     2881 ccatcatcaa caaaagacga gaaggtaagg cgcattgcag aatccttcat ctatgaccta
     2941 aatgctcctg atattattgg tctcatcgag gttcaggaca ataatggacc tactgatgat
     3001 ggcacaacag atgcaacaca aagcgctcag cgcttgattg atgccatcaa ggccttaggt
     3061 ggaccagctt atcaatatgt ggatattgct ccggaaaata acgctgatgg tgggcagccg
     3121 ggcagtaata ttcggacagg cttcctgtat cagccaggac gtgtcagcct ttctgataag
     3181 cctagaggtg gtgttaatga tgcggtgaaa tgggtaaatg gtgagctaag cttgagtgtt
     3241 ggacgtattg acccaacaaa tcctgcttgg aatagtgtta gaaaatcatt ggctgctgag
     3301 tttattttcc aaggccacaa ggttgtggtg gttgccaatc atttgaattc caaacgaggc
     3361 gacaattcat tatatggacg tgttcagccg gtaaccttta aatcagagga aagacgtcat
     3421 gtcttagcaa ggcttttgag ccaatttact aaggaaggtg ctagtcagca ggctaatatc
     3481 gttatgttgg gtgactttaa cgattatgag tttacgaaga ccattaagct gattgaagaa
     3541 ggagatatgg caaatttggt gagcaggcat gagctttctg accgttattc ttacttctat
     3601 agaggaaata accaaacgct tgataacatg cttgtttcac gcaatttgct tggtcgctac
     3661 gagtttgaca tggttcatgt gaattcacca tttatggaag cgcatggacg tgcttctgat
     3721 catgatccgt tgcttcttca gctctccttt ggaaaagaca agccagcagc accatcagat
     3781 cagccaaaga aaacaccagc accagctgcg acaactcaag cctctaaggc aggacgtgca
     3841 cagctattgc caaaaacagg tgataagaca gcgcttatgg taagtatttt aggcttaaca
     3901 gctgtcttta gctcctttag cctgtttagg aaatgtcagg aaaggaagta aaggatttct
     3961 ttggggtagg ccagcagctg agcggctact gcgttttgtc tgctggtgct atataggtgg
     4021 ttgaagcgag cgaagagagg tatgcttcct aggatcatag cacaatatct tatgcttata
     4081 aacgaacaca atgctcctta tgagcattca aaacctatac tcaaaaggaa tataacagct
     4141 gagttaagag ggattgcttt tgacagattg tggtaaaaaa agggatcttg aggaattggc
     4201 tagtgatcta gctgccaaaa tgcgatgtct tgtttgacta tttttcccta ttgggatata
     4261 atgacaatag aaaaagggta gttgtttgcg caactaccct gtgcagaacc gtttaagacg
     4321 gtggcagaat gaaagttaaa aaataatcgt cgacctacca aagttcagac ggttattttt
     4381 tattgtttaa tatgacgatt gcaacgacta agctgattaa ggtaagtaag aaactaccaa
     4441 aagccagcat gagttgaagg gcctcgtaag tagacaataa aacgctcctt tcagttggat
     4501 tttgatgcat tgcccatagg catcaccacc tttcagaaat cagagccacc gtcttagctt
     4561 ttctgtaaag aacattatat cataatcaca tgagaaagcc gttagatttt aaactgatca
     4621 ggcggctttt tggtgttttg ctgtctttta gtggaatcgc ctaagctttg ctgtatagta
     4681 tgggatttta tgctttttgt aagggcttag gctgctatgg cagggtccat gtcctttgtc
     4741 aatagcttag ttttatggta caatgtaggc gttgcctagc aacccttggt gcttagttcc
     4801 ctttcaccaa gcatattaca aacgtggcgg agctgtttat gctctagtct gacgtcaaag
     4861 gagaaacaca tgacaagttt tactgttcgt gactatgttt acattgctct agtggctgcc
     4921 ctttatgtgg ttttgacaat cactccacct ttgaatgcta tttcctatgg catgtatcaa
     4981 tttcgggttg ccgagatgat gaattttttg gctttttacc ataaaaagta tatcattgcg
     5041 gtgaccttgg gctgtatgat tgctaatttt tatagctttg gcttgattga tgttttggtg
     5101 ggtggaggct caacgctcat ttttgttagc ttaggtgtcg ctttatttaa gcaataccaa
     5161 gaggaatatc tcttaaatgg cttgctgaat aaggcctttg tttatttctc actatttttt
     5221 gcgacttcta tgatcaccgt tgcgattgag ctttacttct ttggagcacc atttttccta
     5281 acttggttta ccactgctgt aggggaattt gcttcactta tcattggctc tatgatcatt
     5341 gatcgcttat caaaacgcat taatttacga caataatagt aacatgtagc cttccgtttt
     5401 tgggaggctt tttatgattt tcttctagct aggcaatagc ttatttgcta tgttttgtga
     5461 taaaataaga ctatgaaaaa acgcataaga gaattgactg atctgttaaa tcaataccgt
     5521 caggagtatt acaccaatga cgctccttct gtatctgata gtgagtatga taagctttat
     5581 cgtgagcttg tagagctgga gcagacctat ccagcctata tcctaaagga cagccccaca
     5641 cagctggtgg gcagtacgat tttgacagga tttcagaaat atcagcacca gtatccgctc
     5701 tttagtttgc aggatgcttt ttcacgtgaa gagcttaacg cctttgatca gcggatcaaa
     5761 tcagcctttc ctgaggctga ataccttgct gagctaaaaa ttgatggctt gtccatttcg
     5821 ctggtttatg aggctggtgt tctaaaggtt ggagcgacac gtggcgatgg gactattggc
     5881 gagaatatca ctgaaaacat taagaatatt aaggatattc ccaaacggct aagtcaagca
     5941 cttgatgtga cgatacgggg ggaggcctat atgtcgcgtc aggcctttaa gacgatcaat
     6001 gaagagcgtc aggaaaatgg tgagccagaa tttgccaatc caagaaatgc agcggcagga
     6061 accttgaggc agctggatac taggattgtt gccaagcgac agctagcaac ctttttgtat
     6121 caggaggtag gcctagaaac tgctgatagc cagcaaaaga ccttggagcg cttggccgat
     6181 ttaggctttt cggtcaatag ccactatctg ctgtcctcat cgatgaatga catttgggac
     6241 tttatccaga gcattgaagc tagtagagaa gagctacctt atgagattga tggtgtggtg
     6301 gtcaaggtta atcagttggc gatccaagag gaacttggct ttaccgtcaa ggcaccacgc
     6361 tgggctattg cttataagtt tccagcagaa gaaaaggaag ctgagattgt atctgtggat
     6421 tggacggttg gccgaacagg tgtggtcaca ccaacagcta atttgacccc tgtgcagctg
     6481 gcaggcacca ctgtcagtcg agcgaccttg cataatgttg attatatcgc agaaaaggat
     6541 attcgcattg gggatacggt ggtggtgtat aaggctggag atattattcc agctgttttg
     6601 cgggtggttg aggctaagcg tagggatcag gctccaatgc ccattcctac agcctgtcct
     6661 tcctgccaga gtcagctggt gcattttgag gacgaggtag ctttgcgttg cattaacccc
     6721 ttgtgtccga gcttggttca acggagcttg gagcattttg ccagtcgtca ggcgatgaat
     6781 atcgctggtc ttggtccagc ggttgttgaa aagctttatt ctgctggcct ggtgcatgat
     6841 gtggcagata tttaccgact aagcttggag gatttgctga cgctagatgg tatcaaggaa
     6901 aagtcggctg aaaagctctt ggcagctatt gaacaatcaa aggcaaactc agctgaaaag
     6961 ctcttgtttg gacttggtat tcgtcatatt ggcgcaaagg ctagtcgtct gatattagag
     7021 gcttacggtg atttagaggc gctgttagct gtaaccgctg aagagctcgc tcagattgac
     7081 gggcttggtc tagtgatcgg acaatccctg gtgcagtatt ttcagcaaga gcaagccgct
     7141 cagctgctag ctgaattaaa atcagctggg gttaatctgg cttatttagg ccaaaggcct
     7201 gatcaacagg ctgcgctgtt tggtttaacg gtggtattga caggaaaatt agaaaagcta
     7261 aaccgtaccc aagccatgga aaagctagag cagcttggtg ctaaggtaac aggaagcgtt
     7321 tctaaaaaaa cagatttagt ggttgctggc agcgaggcag gctctaagct ggctaaggcc
     7381 cagcagctgg gtatcagaat tgaagatgag gattggttgc tcaatcttta gtgaggtaat
     7441 aacatgaaaa aacaaatgag ggctcgtctg atttacaatc caacctctgg tcaagaaatc
     7501 atgaaaaaaa acgttgcaga ggtgctggat attttggaag gctttggcta tgaaacctct
     7561 gcctttcaaa cgacagcagc taagcactca gccttaaagg aagcaagaag ggcagctaaa
     7621 gcaggctttg acctcttgat tgctgctggt ggagatggta cgatcaacga agtagtcaat
     7681 ggcattgctc ccctagagaa aagacctaag atggcgatta ttccagcagg aaccaccaat
     7741 gattttgcta gggccttaaa ggtaccaaga ggcaatcccg ttgaggccgc taagctgatt
     7801 ggtaaaaatc aaaccatccg catggatata ggacgtgcta aaaaggatac ttattttatc
     7861 aacatttcag ccgcaggaag cctgacagag ctgacctata gtgtccctag tcagctcaaa
     7921 accatgtttg gctacctggc ttatctggct aagggagtgg agctcttgcc tcgagtgagt
     7981 aatgttccgg tgaaaatcac gcatgatcat ggcatttttg agggagaggt atcaatgatt
     8041 tttgcagcca tcactaattc tgttggtggc tttgaaaaga ttgccccaga tgctaagcta
     8101 gatgatggca tgtttaccct tattttgatt aaaacagcca acctgtttga aattgtgcac
     8161 ctgctgcggt tgatcattga cggtggtaag catgttacgg atcgccgcgt cgaatacatt
     8221 aaaaccagta aaatcaccat tgagccccaa tcagataagc gcatgatgat taatttagat
     8281 ggtgaatatg gtggtgatgc gccaattacc ctagaaaact taaaaaatca catcaccttt
     8341 tttgcaaata ctgatttgat ttcagatgat gcccttgtcc tagaccaaga ggagctggaa
     8401 atcgaagaaa tggtcaagaa atttgcgcat gaggtagagg atttagagca gggattggag
     8461 gaatagggct agttatggat aatgcagtta ttgttcatta tcatagttgc aagggacatt
     8521 attttcaatt aagtctatgg caatggcgag atggtaagct gggcaaggac gcttattttt
     8581 cgaggtttga cagctttgga gcagttgctt atctcactta tccagcacct tattttttga
     8641 gtcatgctta tgtgattgta aaggatcagt tttggcagca tcaaaccgtt gattttcgga
     8701 ttgagcgtga ttatggggtt ccaaagactg aggtgtggct tgttgatggt gatcctacgg
     8761 tttattattc gagacaggct gctgtggcta gtcgacatga tggtagatgt gatgtgcatg
     8821 cctttgatat ggctgtcaat agtcaggcct ttgacaagcg ctggggcttt agtggctggc
     8881 taggctttcg ctatcagcct gaggagacgt cttttcgttt gtgggctcca acagcagaaa
     8941 aggttgagct cattctctat gcttcgactg atgagagagc tagtgttgcc aaggttttgc
     9001 ccatgcagcg tgggcagcag tactcgccag atcatcatgc agaaaacaca tgtggtgtgt
     9061 gggacatcag cctaagaggt gattataatt accatgctta ttgctaccgg gtttattatc
     9121 gcaggcgtac ctttagagac actagggatc cttatgcgat cgcaacgaca gcaaatggca
     9181 aaaggtcaat tgtcattgca ccggagcatt taagaccgca gggcttttca gtgaagcagg
     9241 gtaaggaggc tacctggcgc ttagacaatc ctaatcaggc ggtgatctat gaaatgcatg
     9301 ttcgcgactt ttcaaaatca gaaacctcgg gcgttagctt ggctaatcgt ggcaaattta
     9361 aggggctgat tgagacaggc acgcgcaatg cttttggaga ttcaacctgc tttgattatg
     9421 tcaagtccct tggcattacg catattcagc tccagccggt ctttgaccat catcaattct
     9481 ttgatgaaaa tggagattat gcctataatt ggggctatga ccctgaaaat tacaatgttc
     9541 cagcagccag ctttaccagt aatccgcatg agccagctac ccgtatcctg gaattaaagg
     9601 aggtcattca ggcttatcat gatgcaggca tcaatgtgat catggacgtg gtgtacaatc
     9661 atacctactc atcaagagag tcagcctttc agctgacggt tccggattat tattaccgta
     9721 tgaatcctaa tggctccttt caaaatggct ctggctgtgg caatgaaacg gctagtgaaa
     9781 aggaaatgta tcgcaaatac atgcttgatt cgatcctata ttggaccaat gagtttaaca
     9841 ttgatggctt caggtttgat ctgatgggct tacacgatat tgacaccatg aatcttatcc
     9901 gacaagagct agataagatt gacccaagga tacttgtttt tggtgagggc tgggatatgg
     9961 gagttggtct ggcagctgag cagaaggcta aaaaaggaaa tgccagccaa atgcctggaa
    10021 tcggctttat taatgatgat cagcgtaatg cagttaaggg ggcagaggtc tatgggagct
    10081 tagagaaggg ctttgtatca ggtgcaccga cagaaggact tgtagccaag tctattttgg
    10141 gcagtgatga gctggtctct tattgtacgc ctagtcaggt gatcaattat gttgaagctc
    10201 atgacaacta taacctcaat gatttgctgt gggttttgaa tccagaggac agcaagcagg
    10261 atcatgtcaa acgggttcag ctagcttcag ctatgacgat tctcatgcaa gggatttact
    10321 ttatgcagct gggtcaggaa tttttacgaa caaagcttta cccaacaggt caggataagg
    10381 agctgacaca ggcagaccga gaaagggcga tgaattccta caatgcacct gacaatgtga
    10441 atcaggttga ctggagacag gttagcttgg agcgcgaaac ggttgctatt atgaaaaaac
    10501 taatctatct gaaaactaaa acagctttgt tttcataccc atcatttgag caaatcagac
    10561 agcatgttta cattgagcat gctggtgaaa atacgggctt cattagcttt acagtagaag
    10621 atgaaagaaa gtatcgattg attttctcta gttttagaaa ccgcttgcaa tcatctgcta
    10681 atcatgttat aattgaaaca aatgataagc gctttcaaga tagtgagtcc atgctagatg
    10741 agctgacagc gatgatcctt gacatcacac aatagcctga gtgttctcag gttatttttg
    10801 tttgttgtca aggataaaag ggctgtagtt acagttagca gagacctatt aggaccttgc
    10861 ttatcatatc gcttagcgcc ttgaaaaagg gtttaggagt agggaaagaa gaggtgatgg
    10921 gatggataat gacttagcgc tttatacctt tggcacaggt gagaattttc acatacagga
    10981 ttatctaggt gttcatcgga ttaacaatga cacaggcacc agctatgtct ttagggtatg
    11041 ggcgcccaat gcagaggctg tcagcttgat tggagatttt actgattggc agtccaatcc
    11101 acttgagatg agccgaaatg aggctggcgt gtgggaggtt accactagct tgccgcagga
    11161 aggagatatt tataagtatt gggttaggcg ccaaggtggt cagcttgttg aaaaaattga
    11221 tccagtggcc tttctatttg aagctagacc aggaacgggt gctattgtca aaacccttcc
    11281 agccaaaaaa tggcgtgata gcttatggat gggacggcga aagcgttttg gctttaggca
    11341 gcgtccggtt aatatctatg aggttcatgc ccattcatgg aaaaaagacg aaaacgcaag
    11401 gccctatgac tttagcaagc taaaagaaga gctcattccc tatctcaaga gcatgcacta
    11461 cactcatgtt gagtttatgc cggtcatggc tcacccctta gatatgagct ggggctatca
    11521 gctgatgggc tactttgcct ttgagtcaac ctttggaagc ccagaagcct ttcaggattt
    11581 tgttgaggcc tgtcatctta ataatattgg tgttttgatt gattgggtgc cgggacattt
    11641 tacacaaaat gatgacgcct tagcttattt tgacggtaca gctacctatg aatatcagga
    11701 tcaccatcgt gctcataatt atggctgggg gccctaaatt ttgatttggg taaaactcag
    11761 gtacagtcct ttttgatttc aagtgccctt ttttggctgg aggcttatca tgttgacggc
    11821 attcgagtag atgctgttag caatatgctt tacttggatt atgatcaagg cccttggact
    11881 ccgaatcaat acggtggcaa ccaaaacctt gaggggatag cctttcttca aaaattaacc
    11941 acagttatca aggaaaaaca ccctgatgtg atgatgattg cagaggaggc gacctcagct
    12001 accccaataa ccagccctgt tgcagaaggg ggactaggct ttgattataa gtggaatatg
    12061 ggctggatga atgatattct taggttttac gaagaggatc cttattaccg aaaatacgat
    12121 ttcaatctct tgacctttag ctttatgtat tgctttaagg agcattacat tttacccttt
    12181 tctcacgatg aggttgttca tggcaaaaaa agcctcatgc ataaaatgtg gggggaccgc
    12241 tacaatcaat ttgcaggcct aagaaatctt tacacctatc aaatctgcca cccaggcaag
    12301 aagctgcttt ttatgggatc tgagtttgga cagtttttgg aatggaaata cgatcatcaa
    12361 ttagagtggc aaaatttaga ggacgagctc aatgccaaaa tgcagcattt cacagccagc
    12421 ctaaatcagc tatataagga ccatagcatg ctgtggcaaa atgatgaaac ctatgacggc
    12481 attgatatta ttgatgcaga caataaggac gaatcagtct tgtcgttttg tcgtcaaaac
    12541 aataaaggag agctcctgct ttgtgtcttt aacatgacac ctgttgaaag accaggcttt
    12601 accataggtg tgccgatagc aggtctttat caagaaattt tcaatacaga gcttgaggcc
    12661 tttggaggtg tctggaagga gcacaatccc ttaaccaaca cagtagccaa gaaatggaag
    12721 acttatccgc agaccttgag ctttaccctg cctgcactag gagcaagcat ctggaaaatc
    12781 aagcgtcgtc agaagcaata agctattcat tgcttactta gctgtttcaa ccaaaagaag
    12841 tcactacagt catgaaagga taacgaaatg aagaatggaa tgttagccct catattagca
    12901 gggggacaag gaactcgctt aggaaaattg acacagagca ttgcaaagcc tgctgtgcaa
    12961 tttggaggtc ggtatcgtat cattgatttt gccctatcca attgtgctaa ctcagggatt
    13021 cataatgtgg gggttatcac ccagtaccag cctcttgcct taaataatca tattggcaat
    13081 ggttcgtcat ggggcttaga tggtattaat tctggcgcta cgattttaca gccctactct
    13141 gcaacagagg gaaatcgctg gtttcaagga actagccatg ctatctatca aaatattgat
    13201 tatattgata gcattaaccc tgaatatgtg ctgatcctgt ctggtgatca tatttacaaa
    13261 atggactatg atgacatgct tcagacgcat aaggctaata tggctagctt gactgttgct
    13321 gtgattgatg ttcctctaaa ggaagccagt cgatttggca ttatgaacac agataccaat
    13381 gaccgcattg tcgaatttga agaaaagcct gccaatccaa aatcaaccaa ggcttcaatg
    13441 ggtatttata tctttaattg gcagcgcctt cggaccatgc tggttgacgc agaaaaaaac
    13501 aacattgata tgtctgactt tggtcagcat gtgattccgt cttaccttga gtctggcgag
    13561 cgtgtctaca cctataactt taaaggctac tggaaggacg tcggaacgat tgagtctctc
    13621 tgggaagcca atatggaata catcggtgag gaaaatgccc tagacagtcg tgatcgttct
    13681 tggaagattt attctaaaaa ccatatcgct ccaccaaact ttatcacaga ggacgccgag
    13741 gtcaaggatt ctctggtagt agatggcagc tttatctctg gtaaggtcaa ccattctatc
    13801 ttgtctacca atgtgcaggt aagaaaggga gccgaggtta aggattcctt tatcatgagc
    13861 gatgttatca ttggtgaggg tgcaaggatt acacgagcta ttattggtga gggtgcagtc
    13921 attggtgatc atgtgatcat tgatggcagc aaggacgttc aagtcgtagg ctataatgaa
    13981 gtagtggggg taccaaatga agattgataa atattctgcc attctaggca gctcaattgg
    14041 ctttgctgaa atgaaggggc taacagacac aagaccatta gccaacctac cctttgatgg
    14101 gaaataccgg ctcattgatt ttcaattgtc caaccttgcc aatgcaggtg tccgtagcat
    14161 ctatggtatt tttcgtgggc aaaatatccg ctcagtgttt gatcatatca ggtcaggtcg
    14221 tgaatggggg cttaattcct tactaagtca ttatttcctt ggcttttata acaccaagga
    14281 ggattctaaa gaggctgaca aggactatta tcagcagatt ttgacctatt taaagcgctc
    14341 agggtcagat cagaccattt acatgagctg tgatattctc tgcaatattg agcttgggca
    14401 ggttattcat ctgcacaatg ccaaccatcg caacattacg gttgtctaca agaaaatgcc
    14461 gaccaaggcc atctctaagg ctaacgatat tttagatatt gacgagacag atactgttgt
    14521 tgacaggcga agtctgtctg aggggcagga ggttgaaaaa atgtcagcag gcatttacat
    14581 cgtcaatacc ccatggttaa ttgaacagat ggaaaaagaa gccgaaaaag aaaaccctca
    14641 aaagctacgc ttcctcttac gtgatttgat tgtgtcagag ggcgctcttg gctttgaata
    14701 tactggctat cttgccaata ttcactctgt taaatcttat tttgatgcca atatggacat
    14761 gctggatccg cataagtttt attcactatt atatgctaat cagaaggtct acacgcgtgt
    14821 caaaaatgaa gagtcaacct attttgatgc ggcttctgag gtgaacaatg cccaatttgc
    14881 ttcaggaagc attgtcaagg gctatgtcga gcactcaatt gtctctcgca attgtcgcat
    14941 tacctcacag gcacgtgtta caaatagtat tttattgcca aaggcagtga ttggtgaggg
    15001 tgctgtcatt gattatgcta tcattgataa atccgtaagg gttgcaccag gtgttactat
    15061 tagaggaagc gctgaggagc caatagttgt tgccaagggg actgaggttg ttgaggatat
    15121 gataaaatga agataatgtt tgttgcagca gagggagctc cctttgctaa gacaggtggc
    15181 ctaggcgatg tcattggggc attgcctaaa tcacttgtta aaaatggtca tgaggtgtct
    15241 gtgatactgc cttattatga cgtggttgat caagcctttg gtcagcaggt tgaggacgtc
    15301 ttgtattttt atacgcaggt tggctggaga cgccaatacg tgggcattaa aaagcttgtc
    15361 aaggataagg tgacctttta ctttattgac aatcaaggtt atttctttag aggcaggatc
    15421 tatggtgatt gggacgacgg tgagcgcttt gcctatttcc agctggctgc catagaagca
    15481 atggagaaaa tcggggttat tccagatatt ttgcatgtgc atgattacca taccgctatg
    15541 attcctttcc tattgaaaga aaaataccat tggattcagg cctatcaagc gattcggaca
    15601 gtttttacca ttcataatat cgcatttcaa gggcagtttg atcctggcat gctaggcgat
    15661 ttgtttgatg ttggtataga gcgctacgag gatggcaccc tgcgttggca tgattgcttg
    15721 aattggatga aagcagcagt cctatatgca gatcgggtaa ccactgtctc accctcttat
    15781 gcgcatgaaa ttcagacacc agcctttgga caaggcttgg atcaagtcat gcgaatggag
    15841 gcaggcaagc tatcaggcat tgtgaatggt attgacactg acttatttaa cccagcaagg
    15901 gatcctcatt tgcctgcttc attttcagca gaagacctat caggcaaggc ggctactaaa
    15961 caggccttgc aggagcggtt aggattacca gtcagggcag atgttccatt gattggtatg
    16021 gtttcgcgct tgacggatca aaagggcttt cagcttgttc ttgaggaatt accgcatatc
    16081 ttgcagcagg acgttcagct tgtcttgtta ggaacaggtg accctgatta tgaggctgcc
    16141 ttttcatggt ttgccaaggc ctatccagaa aaactgtctg ctaatattac ctttgatctg
    16201 ccattagctc agcagattta tggggcctgt gatctctttt taatgccaag tgcttttgag
    16261 ccctgcggac tttcgcaaat gatggctatg agatatggcg cgataccgat tgtccatgag
    16321 atcggcggct tgaaggatac tgttgcctcc tacaatgctt atgaaaagac tggaactggt
    16381 tttggctttg atcagttttc aggattttgg ttaacgcaga cgctcttgtt tgcccttgat
    16441 atttaccata accacaagga ggattggcag actattcaac aacatgccat gaccaaggat
    16501 ttttcatggg atacagccag tctggcctac cttgatttat ataaaagctt actataacac
    16561 agaaaaggaa tgggaatgca cgtcacaaaa gaacaattta ttcgagattt taaagatacc
    16621 ttacatgagg aacaattgat caaggttcct gccgcaacag ctgctgagct tttcacctca
    16681 ttagcaaagc ttatccgtaa atactataca gatacttgga ttgaaaggaa tcgttcctta
    16741 accgaacagc agcaaaaaat tgcctattat ttttcgatcg aatttttacc aggaagaatg
    16801 ctagaaacaa atcttcttaa tttaggcatt cttgatacag ttaaagaagc ctttgctgac
    16861 ttgggaattg attttcaagc agtgaagcat gcagagcacg acatggctct aggcaatgga
    16921 ggtctaggac gtttggcagc tgcctttatg gattcgctag cgacaacagg ctatccaggc
    16981 tttggaaatg ggctgcgtta tcgttatggg ctgtttaagc aacggattgt gaatggttat
    17041 caggtagaat taccagattc ttggtttggc tctattggta atgtctggga gatcagaaag
    17101 gatcatgaca ttgtagacgt caagctcttt gggaatgttt acctaaaagc caatcaggac
    17161 ggtaagctag cgccaatcta tgagggagct caggttttga gagctgttcc ctacgatgtt
    17221 cctcagattg gctttgaaaa tgatgtgatt aacaatcttc gcctctggga cgtagaaatc
    17281 ccagaagaac atgagcttga ttacccaacc atcgagtcaa gacgggcagt caaggacatt
    17341 actgccattt tgtacccaga cgacagcagc tatgaaggca aaaagcttag attgatccaa
    17401 gaatatttca tgaccagcgc aggcatccaa accattatca aatcctattt aaagcagggc
    17461 ttgccactta ctgagcttca tcaaaaggta tctgttcata tcaatgatac ccacccagca
    17521 gtagctccag cagagcttat gcggctcttg attgacgact atggcttaga atgggtagac
    17581 gcctgggcga caaccgtaaa aaccatgagc tataccaatc atacgatttt gtcagaagcc
    17641 ttagaaaaat gggacgcaga gctctttaag actgtgctgc cccgcgttta tcaaatcatt
    17701 ttagagattg atcatcgctt tgttgctgaa atggcgcaaa agggtattga tcctcagatc
    17761 attgaaaaca ctagaatcgt taaggacaac cagatttata tggctaatct tgccattatt
    17821 ggtggctatt cggtcaatgg cgttgccaag ctacatacag agttgttaaa gacagatacc
    17881 cttaaggact tttatgcctt gtatcctgaa aaattcaaca acaaaaccaa tggtatcgtg
    17941 caaagacgtt ggacacagat tgctgcgcca gagctatcag cagctattga ccgcacgatt
    18001 ggcaaaggct ggcgcaagga tattcaccag cttcgacaat tgagtcaatt tacagaagat
    18061 ccagctgtgc taaatgattt ttatcaggta aaacaagcag ctaagcagcg cctagccagg
    18121 tatatcctgg aaaaaacagg tcttgaggtt tcaacagagg ctatttttga tgtgcaggtc
    18181 aaacgcctac atgcctacaa gcggcagctc ctgaacgtcc tgcatattat gaagctttac
    18241 cttgatttga aggctaatcc agatttagat atggtgccta gagtctttat tttcggcgca
    18301 aaggctgcac caggctatca ttttgccaag tcggtgatca aaatcatcaa tgagctggct
    18361 aatctcatta accatgatac cagtctcaaa ggaaagctaa aggttgtttt tcttgaaaat
    18421 tataacgtga gtctagcaga gctcattatc cctgcggcag atatttcaga gcagatttca
    18481 ctggcctcca aggaagcctc aggaacatca aacatgaaat ttatgatgac tggtgctatc
    18541 accctagcga cccttgatgg ggcaaacatt gaaatcaaag acgaggtcgg agaggaaaac
    18601 attgtgatct ttggtatgga taaggatcag gtctatgacc actatgccaa gcatgattat
    18661 tattcaagag gcctatatga gagcgaccct cagattaaag cagtagtcga cgcttttgtc
    18721 aatggcacca ttccaaatag tcaacacgaa ggtatggaaa tctatgatgc cctaatcacg
    18781 cataatgatg aatacttctt gctagaagac ttttcttcct atgtaaaagc acaggctaag
    18841 attgatcggc tctaccgcca aaaggataga tggtcaaaaa tgtcgctcat caacattgcc
    18901 cattctgaca agtttacatc agatgatacc atcacccagt atgccaagga catttggcag
    18961 ctaaaacgct aatccatcaa ggaagaaaaa gcattagtta ccttagattg aagagagtgt
    19021 cttttgagac cattttcttc aatctttttt gattgcaaaa gaccttggga atcagatcag
    19081 ctgcctgcct aatactttgg cctatcaagg tattttggaa tttgttaatc tttttgttat
    19141 aatagtggtg tgaagctatt ttttaaatga aaaagccaac acttcaagat ggtgttaaag
    19201 taaggttagt attagtctaa gaaagcgtaa ccacattaaa gaaagctgtt gacattctca
    19261 attttaagga atagaataac aaagtaaaaa atttttaaaa ggagtattct attatgaatc
    19321 ctattttcgc attggctctt gcctgctttg gtgtatcact tgccgaaggc tttttgatgg
    19381 ctaatctctt taaatcagcg tcacgccaac cagaaattat cggtcaatta cgttccttga
    19441 tgatcctagg tgttgccttt attgaaggta ccttcttcgt tacccttgtt atggccttca
    19501 ttctaaaata acagcctatt tgatatagaa aaggagggta ttaaatggaa gaagctaaag
    19561 taccgatggt agagcttggt ccaataacct ttaatttgac cctacttgct gtttgtattg
    19621 ttactatcct actgatattt ggctttgttt tttgggcaag tcgtcagatg acattaaaac
    19681 caaaaggcaa gcaaactgcg ttagaatatt taatcagctt tgttaatggt attggggaag
    19741 agcatttgga tagtcatctt cagaagtctt attcgctttt actttttacc atttttcttt
    19801 ttgtggcagt tgccaacaac ttgggcttat ttacaaagct agaaacaacc agtggctaca
    19861 acctatggac atcgccaaca gctaatttgg cctttgacct agccctatct ctgtttgtga
    19921 cgcttcttgt tcatatcgaa ggcattagac gtcgtggttt tggcgcttat ttaaaacgct
    19981 ttgcgacacc ttggccaatg actccgatga acctattaga agaatttacc aacttcctat
    20041 cacttgctat caggctgttt ggtaatatct ttgcaggaga ggttgtgaca ggcttgattg
    20101 ttcagctggc caattatcgc ctgtattggt ggccaattgc tttccttgtt aatatagcat
    20161 ggacagcctt ttccatattt atttcctgca tacaagcctt tgtatttaca aaattaacag
    20221 caacgtattt aggaaaaaaa gttaatgaat cagaagaata agaagggagg acaaacgaat
    20281 gtcagttaca attggtgagc tcattgggaa ttttattctg gtaacaggct ctgtcatcgt
    20341 cttgttgctc ttgattaaag cctttgcttg gggtgctatc gaagctgttt tacaggcacg
    20401 ctcacagcaa atttcacagg atattgacca agcagagcag gcgcgtctca acgcccagca
    20461 gcttgaaaag gaaggtcaag ccaatctaga agccagcaga tcagaggcta gtcagattgt
    20521 tgaggcagcc aaagaaactg gtaaagcaca ggagacacgc attgtagcag aggctacaga
    20581 agaggcagat cgcctaaaag cagcagcgtt gacagatatc gaacacagca agtcagaggc
    20641 tatttcagcc gttaagacag aaatgtcaga tttgacagtt ttactagcag aaaaaattat
    20701 gggagccaat cttgataagg cggctcaaag ccagcttatt gatcgctatc ttgatgattt
    20761 aggagaggct taatgaccaa aaaagaacaa gctcttatcg agcaatatgc aaaaagtctt
    20821 gtgcaggtct gtcaggagcg agacactctt gaagcactgc aggctgatgt gcttgccatt
    20881 ttagaggttt ttaaagctac taatcttgct aagacattgt caagcttagc ggttccacgt
    20941 gctaaaaggc ttgagctagt aaggcagctt caaggagata atatcgttta tctgaataac
    21001 ttgctagaag ttatgctgca aaatgagcgt gaagcttatt tatatcaagt gcttctaagg
    21061 gttttatccg agctggctag tgtctcaaat caatatgacg tgacagttac atcagcagtt
    21121 cctttaagtg aggagcaaaa gcagcgtgtg cgtacagtgg tttcaaagag acttgcagta
    21181 aagacaggtc gcttaatcga aaaggtagat ccttctttaa ttggaggatt tatgattagc
    21241 gtcaataata aggtaattga tacaagcatt cgtcgtcaat tacaagcatt taaaatgaat
    21301 ttaaaataga aagtggtgtg acttttggca attaatgcac aagaaattag cgctttaatt
    21361 aaaaagcaaa ttgagaactt ccagccaaat ttcgatgtca cagaaactgg agttgttacc
    21421 tatattggtg atgggattgc acgtgctcgt ggcttagaca atgcgatgag tggcgagctt
    21481 cttgaatttt caaatggtac cttcggtatg gctcaaaacc tagagtcaaa cgatgttggt
    21541 atcattattc ttggtgattt ttcaacgatt cgtgagggtg atgaagtcaa acgtaccggt
    21601 aaaattatgg aagtgccagt cggtgaagct ctcattggac gtgtggtcaa tccacttggt
    21661 cagcctgttg atggcttagg tgacattgag acaactggct ttaggcctgt tgaaactcca
    21721 gctcctggtg ttatgcagcg taagtctgtt tttgagtcct tacaaaccgg tctaaaggct
    21781 attgatgctt tggttccgat cggtcgtggc cagcgcgagc tgattatcgg tgaccgtcag
    21841 acaggtaaga cgtctgtagc cattgatgcc atcttgaatc aaaaggggca ggacatgatt
    21901 tgtatctatg tcgctattgg tcaaaaggaa tcaacagttc ggacacaggt tgaaacccta
    21961 cgtcgttatg gtgctttgga ttataccatt gttgtaacgg cttctgcttc acagccatca
    22021 cccttgctgt ttattgcacc ttatgctggt gttgcgatgg cagaagagtt tatgtacaat
    22081 ggcaagcacg ttttgattgt ttatgatgac ctgtctaagc aggcggtagc ttatcgtgaa
    22141 ttgtcgctct tgcttcgtcg cccaccaggt cgtgaggcct atccaggaga tgttttctac
    22201 ctgcatagcc gcttgcttga gcgctcagct aaggtgtctg atgacttagg tggtggctca
    22261 attacagcct taccatttat tgagacgcag gctggggata tctctgccta cattgcgaca
    22321 aacgtgattt cgattacaga tggtcagatt ttcttgcaag aggatctctt taactcagga
    22381 atccgcccag ctattgatgc tggctcgtca gtatctcgtg tcggtggctc tgcacagatc
    22441 aaggctatga aaagggttgc agggactttg cgtcttgacc tagcctctta tcgtgagtta
    22501 gaagccttta cacaatttgg ctcagatcta gatgcagcaa cgcaagcaaa attaaatcgt
    22561 ggtcgtcgta ctgttgaaat cctaaagcag ccactgcaca agcccttgcc tgttgaaaag
    22621 caggtggtca ttttgtacgc tttgacgcat ggatttttag atgatgttcc tgtagatgat
    22681 attttagcct ttgaagaagc actttatgac tactttgatg cgcattatga tcacttattt
    22741 gaaacaatcc gtacaaccaa agaccttccg caggaggctg agctggacgt tgctattcag
    22801 gccttcaaag cacagtcaaa ctttaaataa aagagggggg tactagtatg gcaggctctc
    22861 taagtgaaat taaggctaaa atcatttcaa ccgaaaaaac aagcaaaatc actagcgcca
    22921 tgcgtatggt ttcttctgca aagcttgtta aatctgagca agcagctcgt gattttcaaa
    22981 tctatgcttc aaagattcgt cagattacaa cagacttact gaaatcagac ctgacaacag
    23041 gctcagataa tcccatgctg gtgtctcgtc ctgtgaaaaa gacaggctat attgttatta
    23101 cctctgataa aggactggtc ggtggttaca attcaaaaat cttaaagtcc attatggaca
    23161 tgattcagga ataccatgcc gctggcgatt atgagattat ctcaattggc agcatcggct
    23221 cagatttttt taaggccaga ggtatgaatg ttgcctttga gctgcgcggc ctagcagatc
    23281 agccaagctt tgatcaggtc ggaaggatta tctctcagtc tgtaggtatg tttgtcaatg
    23341 agatttttga tgagctgtac gtctgctaca atcaccatgt caatagcttg acgagccagg
    23401 ttcgggttca gcgcatgctg ccgatttctg atttggttgc cgaggaggcc gcagaagaag
    23461 gtgtcactgg atttgaatta gagccaaacc gtcatgtgat tttggagcag ctgctgccgc
    23521 aatttactga aagcttaatt tatggtgcga ttattgatgc aaaaacagca gagcatgctg
    23581 ctggcatgac tgcaatgcag actgccactg acaatgccaa gcatgtgatc aatgatttga
    23641 ccatccagta caatcgtgcg cgtcaggcgg ccattacaca agaaattaca gaaattgtag
    23701 ctggtgctaa tgcacttgaa taagcttatt gtatgctgat agcgctctag cagagaccta
    23761 ttagcactta atgtcatctt caaagctaga tgacatttgg gattaatgag ctaggggcct
    23821 tttaccctta gctactcgaa tttagaaaaa ttcagcttaa tcccctacta tcgaatataa
    23881 ggagaaaaac atgagctcag gcaaaattgc tcaggttgtt ggtccagttg tagacgttgt
    23941 gtttgcgagt ggggacaaac taccagagat taataatgcg ttgatagttt ataaagatgg
    24001 cgataaaaag caaaaaatcg ttctcgaggt tgccctagag cttggagacg gtatggtacg
    24061 tacaattgct atggaatcaa ccgatgggct tacacgtgga ttagaggttc ttgatactgg
    24121 tcgtgccatt agtgtaccag ttggtaaaga gactctaggt cgtgttttca acgttcttgg
    24181 tgaaaccatc gacctagaag caccatttgc agatgatgtt aatcgtgaac cgatccataa
    24241 aaaagcacca gcctttgatg aattgtcaac atcatcagaa attcttgaaa caggtatcaa
    24301 ggttattgac ctgcttgccc cttacttaaa gggtggtaag gtcggtcttt tcggtggtgc
    24361 cggagttggt aaaaccgttc ttatccaaga attaatccac aatatcgctc aagagcatgg
    24421 tgggatctcg gtatttaccg gtgttggtga gcgtacgcgt gaaggaaatg acctttactg
    24481 ggaaatgaag gaatcaggcg ttattgaaaa aacagccatg gtttttggtc agatgaatga
    24541 accaccagga gcccgtatgc gtgttgcctt gaccggcttg acaattgctg aatatttccg
    24601 cgatgttgaa ggccaagacg tcctgctctt cattgacaat attttccgct ttactcaagc
    24661 aggctcagag gtatcagccc ttctaggtcg tatgccttca gccgttggtt accagccaac
    24721 acttgccact gaaatgggac aattgcaaga gcgtatcacc tcaacgaaaa aaggctctgt
    24781 tacctctatc caagccatct acgtgccagc tgatgactac actgatccgg cgccggcaac
    24841 agcatttgct cacttggatt ctacaactaa ccttgagcgt aagctgacgc agatggggat
    24901 ttacccagcg gttgatccac tggcttcaag ttcacgcgcg ctgtcaccag aaattgttgg
    24961 tgaggagcac tatgcagtag ccacagaggt tcagcgtgtc ttgcagcgct atcgtgaatt
    25021 gcaggatatc attgctatct taggtatgga cgagctgtca gaagaggaaa agacattggt
    25081 aggacgtgcg cgtcggattc agttcttctt atcgcaaaac tttaacgtcg cagaacagtt
    25141 tacaggcctt cctggctctt atgttccagt tgccgaaacc gttcgtggct tcaaggaaat
    25201 cctagaagga aagcatgacc accttccaga agacgccttt cgtgctgttg gaccaattga
    25261 ggacgtgatc gaaaaagcta agaaaatggg cttttagtga ggtgatgcca tgacacaaat
    25321 gactgttcag gtggttacgc cagatgggat caaatatgat catcatgcta agttcatctc
    25381 agtaacgaca ccagatggtg agatggggat cttacctaac cacatcaatg tgattgctcc
    25441 tttacaggtg catgaaatga agattcgtcg tgtcagtgaa gacgatcgcg ttgattgggt
    25501 tgctatcaat ggtgggatca ttgagatcaa agacaacgtg gttaccattg ttgcagattc
    25561 agccgaacgt gatcgtgata ttgatgttag ccgagcagag cgggcaaaat tgcgagcaga
    25621 gcgtgacatt gcagaggctg aaaccactca tgatattgat gaggtgcggc gtgctaaggt
    25681 tgctttgcga cgtgccttga accgcatcaa tgttagtaaa aaatagtaaa atgagtctaa
    25741 cctaccaatt taaccaagac agagcgagta gcgctgctta ggaaagggtg tagatagact
    25801 cttttatctt tttatagaaa aaataccctc ttt
//
LOCUS       DARYVE010000024        24179 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYVE010000024 DARYVE010000000
VERSION     DARYVE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24179
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(93..869)
                     /locus_tag="TVW25_000960"
                     /pseudo
     CDS             complement(93..869)
                     /locus_tag="TVW25_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            complement(965..2512)
                     /locus_tag="TVW25_000961"
     CDS             complement(965..2512)
                     /locus_tag="TVW25_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1378605.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            complement(2487..2726)
                     /locus_tag="TVW25_000962"
     CDS             complement(2487..2726)
                     /locus_tag="TVW25_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1378606.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            complement(2739..4862)
                     /locus_tag="TVW25_000963"
     CDS             complement(2739..4862)
                     /locus_tag="TVW25_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1378607.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            complement(4866..7295)
                     /locus_tag="TVW25_000964"
     CDS             complement(4866..7295)
                     /locus_tag="TVW25_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1378608.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(7207..7596)
                     /locus_tag="TVW25_000965"
     CDS             complement(7207..7596)
                     /locus_tag="TVW25_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1378609.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            complement(7600..7863)
                     /locus_tag="TVW25_000966"
     CDS             complement(7600..7863)
                     /locus_tag="TVW25_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1378610.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            complement(7883..8749)
                     /locus_tag="TVW25_000967"
                     /pseudo
     CDS             complement(7883..8749)
                     /locus_tag="TVW25_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8769..8984)
                     /locus_tag="TVW25_000968"
     CDS             complement(8769..8984)
                     /locus_tag="TVW25_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1378611.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            complement(8988..9299)
                     /locus_tag="TVW25_000969"
     CDS             complement(8988..9299)
                     /locus_tag="TVW25_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1378612.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(9463..11244)
                     /locus_tag="TVW25_000970"
                     /pseudo
     CDS             complement(9463..11244)
                     /locus_tag="TVW25_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(11241..11726)
                     /locus_tag="TVW25_000971"
     CDS             complement(11241..11726)
                     /locus_tag="TVW25_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1378613.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            complement(11723..12497)
                     /locus_tag="TVW25_000972"
                     /pseudo
     CDS             complement(11723..12497)
                     /locus_tag="TVW25_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(12494..13273)
                     /locus_tag="TVW25_000973"
     CDS             complement(12494..13273)
                     /locus_tag="TVW25_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1378614.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            complement(13360..13641)
                     /locus_tag="TVW25_000974"
     CDS             complement(13360..13641)
                     /locus_tag="TVW25_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378615.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TVW25_000975"
     CDS             complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TVW25_000975"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1378616.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(15370..16800)
                     /locus_tag="TVW25_000976"
     CDS             complement(15370..16800)
                     /locus_tag="TVW25_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1378617.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(16999..17493)
                     /locus_tag="TVW25_000977"
     CDS             complement(16999..17493)
                     /locus_tag="TVW25_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1378618.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TVW25_000978"
     CDS             complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TVW25_000978"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1378619.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(18902..19840)
                     /locus_tag="TVW25_000979"
     CDS             complement(18902..19840)
                     /locus_tag="TVW25_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1378620.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(19842..20702)
                     /locus_tag="TVW25_000980"
     CDS             complement(19842..20702)
                     /locus_tag="TVW25_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1378621.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(20719..22002)
                     /locus_tag="TVW25_000981"
     CDS             complement(20719..22002)
                     /locus_tag="TVW25_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1378622.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(21995..22549)
                     /locus_tag="TVW25_000982"
     CDS             complement(21995..22549)
                     /locus_tag="TVW25_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378623.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(22843..24132)
                     /locus_tag="TVW25_000983"
     CDS             complement(22843..24132)
                     /locus_tag="TVW25_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1378624.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         6485 a         5524 c         3924 g         8246 t
ORIGIN      
        1 gcattaaagc aaagctaaaa ggacttagcc ctgtgcaata cagaactaaa tcctttcaat
       61 aattattcgt ccaacttttt gggggcagta catttagtaa tcttttcttt ttgaatgaca
      121 tcagttattt caatcttatt gcccactaaa gttaagagct gctctgctgc tatttcatca
      181 tcaattctat ctgttgaaag tgtaaagcta tttgtagaaa gctctaccgt ataatatttt
      241 tctttcttaa agtttgctat ctcatcatct ctttttacga tcatagcaag agtcggtgtt
      301 tgtactctgc caacactgta attttgctta tacagacaag aatagagcct gctgatattc
      361 attccgacaa gccagtcagc gatagctctt gcctgtgccg actcaaagag attatcgtaa
      421 tcttttccgt cttttagatg atcaaagcca tctttaatgg cagtatcttc catagatgaa
      481 atccaaaggt gtttcatctt ctttttacaa ttcacttgat tatatacaag tctaaaaatg
      541 ctctcccctt ctctacctgc atcgcacgca ttgataaccg tatcaatttc tttgtcgttc
      601 atcaactttt taaggatgtt aaattgtttc ttggttgact ttgccacttc atacttatag
      661 tccttgggga taatcggtaa atcaaccata ttccacttgg catacttttc atcataaaca
      721 tccggatttg ccatttgaat taagtgtcca acacaccaag atactttgta tccatttccc
      781 tcataatatc cgtctttctt tttatttgct ccaagtactt ttgcaatact taatgctaca
      841 cttggttttt ctgcaatgac taacttcatt tctgtactgc ctcctgtttt caatataaaa
      901 gggcgaaaga ttttattctc ccgccctgca tttgcaccaa atactgtatt tttttggtgc
      961 agcattactg ctcatcttcc gcttctactt catctacatc atttgtttct tcctcgcttt
     1021 cagcttcaga aaagaaatca tcatcttctt cctctaatgc ttcaagctcc ttatcttctt
     1081 tcttttttac aaccttaaag tagtatcctg ctcccaatgc tccgcctaca acaagaagca
     1141 gaataatata tgttcctaaa ttactctttt cttctttttt ctcaggcttt acttcttcct
     1201 taacaggttc ttcttttaca atctcctgct ttggagcttc ttttttctct accatgttaa
     1261 gcaaatcatc ttcggatact tctgtaagaa gcatgacatt ctcactatcc tcatcgtggt
     1321 tgatgatgag atgaaaggtc ttaccgtttt tagtttgaaa ggtaataaac tgtcttgcat
     1381 cagcggaata ttgatccgtt tctttattat cgctgctatc cccatgatga atcggataat
     1441 ctttatttcc attatcttta ttttctgtaa cagttcctct tgcctttgac ggagatgaag
     1501 ctactccctt attggtattt acattactac ttgccccctc cattgacgaa tcttgactgc
     1561 tgttattagc aggtgctttt gctgtcaatt tattagaata gcgaacttcc ttttctttct
     1621 cctttacttc tgttttgctt gtatcctttg tagcattccc tgaactcacc gtatcagatg
     1681 agcctttacc ggaactactt acagaagtct gtggtgtttg gggagaaatg cttgagcttg
     1741 tcttaattcc ggaaatagga ctaatcggtg taacagaatt tattgcttca gaagatttct
     1801 ttgtttcagt tgcctttttc tcaagctctt tcaccttatc agtcagctta tctatttcct
     1861 ttttcatatc ttctgataag tccttatttc ctttatcttt cttcattttc tctttcaggc
     1921 tgtcaatttc atcttcaagg tctttgattt tttctttctg cttatccttg tctttaagct
     1981 caccatttaa cttatcaaat ttttcttgaa gctctttagc ctctttttcc atcttagaaa
     2041 tatcgtcttt agaaagctct gtctgtgtgc ctttatcctc cgtttttgta gcttctgttt
     2101 gcgtgctttc gtcctgcttt ggtttttctt cttccgtttg cgtttcctta tccttaacct
     2161 cagtctttgc taccttacgg ataatttcat catttccatc tccctttact tcataaaaca
     2221 ggaattcatc aataaatttc atatcatcag ggagcattgg aagatcgcca ctatcaagaa
     2281 gctgtccttt ctctgcctta atcttttctt ccttaaatac cttttcatct tcaaagatat
     2341 actttacatt tacttcaact tccgtttgga cagcttcgtt ttttgtagga gcgtcagagc
     2401 ttttctcctt ggcgtaaaca accgtccaaa gtcctaaaat gcagctaata cttacaatta
     2461 ctgcaagtgc tgctgtccaa aacttattat tctttttcaa actggttttc atttgtcctc
     2521 tcctttttca gttctgcttt ttctctgttt acctttgtca ttaaatcaga aattgtgatg
     2581 ttgttctttc tgcaaatcat gatgatttct tcattttcaa gttcttcttc acgaataaat
     2641 aaaggctcca attcttcatc aatcagagcc tttttatcct ttaacttttt tattctgttt
     2701 tttactgctg tcagttcttt tttcatattg ttccctcctt atctgtttac atttggtgga
     2761 aaaccaaagc ctaccggatg gtgtttacaa aaagtcgcaa tccaatcatc taaagtagtt
     2821 actcttatat aaccgatatt atcaataacc ttgccgtctc cgatatagat tccgacatga
     2881 ccataggtaa gtcctgctgt gcttccgcta ctgctgcttt ctaccgctac aagcattcct
     2941 accttgagct ttgacctatc ggatgtaaag gtatagtttc gatacatatc attagcattt
     3001 cctccgatat atccaagtcc cgcattttgg taaacttgcg atacccacat ggcacaccag
     3061 cctgcacccg gagatggagt gatatatgca gcattaacaa tcttcttttg tacttccgaa
     3121 gatgcctcat actctttccc accacctaca ccgccattag cactgataag gtcagaattt
     3181 ctaaaggctt ctcccatatt tccttgagca aggaataagg cttcatagtg ctttaaatta
     3241 tcgggatagt ctttaaagac ccttcggata atgctgtcca tctctttttt atgaagcgtt
     3301 acaatgagct tcttatattc ataaggctct tcatggcttt cggtatattc attgccatct
     3361 tcatcggtat aggtttctgt aactgtcctg tatctgattt caatttcttc cctgtattca
     3421 aggtcataca tggactcaaa caattctttt aatatggttt ctacttccga tacactcttt
     3481 acctctccgc accttgatgt aatgtaggat aaaagctcat ggacattatg accgatatac
     3541 tctgtgttgt ttaagatata ctcatcatat ccgggataat tctcttctac atgatccact
     3601 tcactttgaa gctcactctc catagcagaa aacttctgat tgatttcact tagaacattt
     3661 ggctttgata aatagcttgt tgtaagaaca gagtttgtag agttcataaa gcctgtcatg
     3721 cctgttcctg caaagttaat cacaaaattt cctaagatga tgatacctac gaagataagc
     3781 attagtcctt tggcttttcg gataatcata tcctttgagc ttttcagtgt tccgataagt
     3841 ccctctttaa tccgatctct gagtcttgac ttattctcac gagaaatcgc tgcctttacc
     3901 tgatttttct tttgaaatct tttataggca cttgctcttt tatactcatc tgtctttttc
     3961 agttcctctt tggcatcacg aaactctaac ttggatttac gctttctgat tttatagtcc
     4021 ttatttgtaa gctcatatcc ttttttagct cttttcttat ctgagtatct ctttatacca
     4081 tgaatgagtt ttgaacttgc atcggctgtt ttttctcccg cttctacgcc tttattttca
     4141 tcacttccat gagaaaggta atctcttacg gtttcacttc ctttggcaag tcctgacagg
     4201 gcagatactt ttaccatatc tttcttcagc tttttctttt ggtcttttga aagactgcta
     4261 tgttcttttt cgcccgcaac atctttccct gcctttttat cttcaggctt attctctttt
     4321 ggtacatcgt ccttttttct tgtatagagg ctttcggaat agtttttcct tttatactta
     4381 ttcttttgag ccttatgatt tttagaggga ttttctaatg atttttcttt ttgaggtaga
     4441 ttatcctcta catcataggt tgattcaaag tagtcgctgt ccctaaaatc attatcgtat
     4501 ctgtctatga ttccatcatt atcaaggtct tgtcctaaag aatcatagat tttcccgttc
     4561 tttacctcag tatcatagtc agcctttcct gcttcattta cacttccctt atcagaagcc
     4621 ctatactttg catttctttt agaagtcccc tctatctgct cattttcaga tcttaccttg
     4681 cttatcttct catgaacctt gtcctgaaat ctatctttgt catggacaat ttttcctctg
     4741 taatcatcgt tatgctttag cttactttct tcaggtatag agcttgtttc agctttaagc
     4801 atctcccttt caaggcttgc cttatgcctt tctctaaaat cttttttcag cttcccatcc
     4861 ataagctacc tcacttcttc aggcttggta gtcatcttct gataaagaat tgtatctttc
     4921 ggaaacttat caaggaaagg cacaatggta tttccaaaga aaagtagtcc ctcgccctca
     4981 ttggagttcg taacatatct aagctgcgga agtgagattt taagtttcct tgcaagtatt
     5041 tccctatctc ccgaagcctg atttaacatt aagacaaagt ccgtattatc aaagatattt
     5101 tcaatttcct tactcataag taggtctttg acattttgcg tgataccagt cgggattcct
     5161 ccccattttc taaaacgctt ccaaatctct accgaatatg aagctgtctg ctcatctttt
     5221 aacagcaagt gaaactcatc tatatagtac cttgtagcct tgtttcctct gttttgcgat
     5281 accttattcc acacctgatc ctgtataaca agcataccta ttttctttaa ttgacttcca
     5341 agctccttaa tatcaaaaca aagtagcttc ttatttaagt ccacatttga cctgtgatta
     5401 aagacattaa gagaacctga aacataaatt tccatctctg ttgccagctt tttccctacc
     5461 ttttcttcct gcccttttaa catatcgtat aggtcttgaa gtataggcat attgtcataa
     5521 gtcggatttt caaagtacct ttcgtaaatc ttaggtaagc atctatctat aacggacttt
     5581 tcttccgctg taagtccact accaccaact acaagctcaa gcatagacat aatgaagttt
     5641 gccttgtctt taagaggtgc gtccccatca ccgtagttca tatttatatc aagtggattc
     5701 aggtaatctt ttgacttact gctgacctta atgacttctc cattaaactg tcttacaagg
     5761 tttccatact ctccctccgg atcacagata atcacatcat cgtccgttac taaaatcgca
     5821 tttgccatct ctcttttggc actaaaggac ttaccactac ccggagttcc taagattaga
     5881 ccgtttgggt tctttaattt ctttcgatcc gccataatca ggttatggct taaagcgttt
     5941 agtccatagt ataggctatt acttgaattg ataaaaagct cctctgttgt aaaaggcata
     6001 aagactgctg ttgatgatga ggttagccct ctatctattt caatcttgtt taccccaaga
     6061 ggcagcacgc tcactaagcc ttgttcctgc gtatggtcaa gtcttttcaa tttacagtta
     6121 tgcttgtttg caatggagct tatctgagct atggtgttat cgagcttttg cactgtcctt
     6181 gcaaaattca taaagacaat acttacaaca aacatacgct catctcttgt ctgtaaatct
     6241 tttaaaagac tttttacatc ttctccgtaa gtaattaaat cacttggaag aatgtccatg
     6301 tcatagcctg accttacagc tttcttgttt tcctcaattc gcatcttatc aatatcggtg
     6361 ttttttcgtt ttaccatctt gatggcttct gactggtcaa tcgccttaat atgaaaagat
     6421 atattgatgt tatcatcaat atccaaaaac tccgataaca tacggtctga aagctcactt
     6481 gcaaggattt gaaaatgact tgttgctccg ataaacttcc caaacttgaa atacctgctt
     6541 ggcataaagt taaattcatc aggcacgata tatgttttgg tactttcctt tttcttcagg
     6601 tctttgtagg aaaactcaaa ggtcttattc ggatttaata tatcgtgaag aatctttagc
     6661 ctttcctcta ctgtaagact ttcagctctt acccccatgc ttttgagatt agataatata
     6721 tctatatcca atctttcaag ttttgatgta gcctgttcta aattgtctgc ctctactgta
     6781 aaggttacat actttgattt tttcagtccg ttatttcctt ttacaatctg actttttagc
     6841 atctctctaa actcaagtcg tatatcgtca aatccgtccc ctttatccgg tatctgaatt
     6901 gccgatttca tttcttcgtt tcgtccaagc tgattgatgt aggaaaactc aatcgctatg
     6961 cttggatcaa aggaatttag aaagtttgca aactgattaa aaatcaaatc cctatcttca
     7021 tctaaagcaa gctgatagtt aatgtcctga aaggctatgc ttttactgaa gtgcttttca
     7081 tcgagctggc atatcccgct ttttaagagt ctaagatagg gaatggtatc ttctaccgta
     7141 tagcgttttt gctcttttct aaagataaga tcaagtagtc cgctcttttc tttgttagac
     7201 tttcccttac tttgctttaa gtcctttctc tcctttttta atgccttttt gttttcttct
     7261 aactttagtt gctgaatttt tcttttcttg ttcaaggtaa acctcctttc tcactctctt
     7321 tgccggctga taaaacttat gaaggtagat atgcttaaaa tatttctcaa aggtcagtcc
     7381 gtccttttca aaaagtgtga taaaaaagat tggaagtgtg gacacgataa ggaatatgaa
     7441 agctatatcg tttggtacta cctttctcat aaataaatag acaggtattc caacaagtcc
     7501 tgcaatggta aatcctatga gctgtctttt tgtaaggtta aaggctacct ttgtcttgac
     7561 cttctttaag tccttgggta ttggtacata cgccatagct tacctcccat cttctttacc
     7621 ctttgaaaac tcctcaaagt gttcatatac agagccgatt tcatcctgaa taattgcaag
     7681 ctgttcatct gtattcttgt tatatctttg ctgcattaag caaaaatcat tatggcagcg
     7741 accgatgtcc tgtgttcttt cttctaattc ggcagctttg ttatgaagcc tgattctatc
     7801 aattaccgcc ataatgcctg cgaccattac tactgctgta aatactgttt ttcttttatt
     7861 catactatct ttcctttctt ttttagtgtg catttaatac gcttttggcc agtgttccgc
     7921 tctttagcat cattaacccc agcaaaaccg cataaccaag tatcgtcatg gtacttgtgt
     7981 gtatatctgt tatttcaatc gtcttaacta atactgcgta aattccaaga caaaccatta
     8041 aaaagagtcc ttgtagtcca agtgcaaata atcctttgat gtaatttgtg ccaatttgcc
     8101 cccattcttt gtttcccatc gtggcaaatg gaatggctga aaccgatgaa taaacataaa
     8161 tctcaaacat ccttccgtaa accacaagca taatcactat ggaaattgcc tgtatggcaa
     8221 ctttaatgag cgaggtttca aagagaatca tgataagctc tccaagtccc ttttctttta
     8281 gggtatccat catcgccact atctgatctc cggaaacggt ggcagaggtg tttatcaccc
     8341 ctgccgcctt atttaccata tgctgtgcta catcaaagac cgccattgaa aattcaaaag
     8401 cgtgagatac caaccataca gcaattcaca tcttgatgat gtacttgaaa aattcaaatg
     8461 tatccgtatt atcatgtagg ttatttttct gtataaccat attgataagc tcgatacaaa
     8521 ggactgctgt gataattagt cccgctatgg gaataatgac cgaatcgtta atgcttttaa
     8581 taaaggtaaa tacatctcca ttccacccca taggagtttt tcctacatct gttgcaactg
     8641 caccaacctt gtcgttgatg tcaagaaaca tggactctaa gtttgcttgg ataccgccca
     8701 gtagaagctc cttaaagaat tcttctattt tgtcgaatat cccaaacatc taagctctcc
     8761 ttttcttctt atctgagtac atttgcaaga agtggaatca gcttaagtcc gataaggaca
     8821 atacctcctc ccgccatcaa ttgcttgatc ccttgacttt tggctcccgg attatcgtta
     8881 ccataacctt ccatcaggtt aatgacaccc catgctccaa gtcctgctcc tactgccata
     8941 accaaaatct ttaatacatt tactgcctgt gcgaaaaatt ccataattta ttcctcctca
     9001 ttttcttctt tcttttcaat cttgttgtat gacttcacta caaaattttt gtaagtcttt
     9061 ccctcttttt cacgcttctt aaagtagccg aatacatgaa tcaaatcgcc cttttcaaag
     9121 tcctttgctt tatccgcttt ttctccatag gctgcacaat tgatgtactc cttgccttta
     9181 ccgtacttct ttacaagcgt aaaatttaca acttctactt ctttaccctc tttttcaaaa
     9241 cttgagaaag taggttctgc cactaagttg gcgttgatgt taatcatttc ttgcttcatt
     9301 aaaaatttct ccttttcatt tcaataaaaa aagcgaccgg aagtattact tttccaatcg
     9361 ctatactcat actatttagt tttttactca gtgggacttc tgatccttat catcttgcct
     9421 ccttactttt gcataaaaaa gcagcaaatc tattttgtag acttactgca ttcttgtaat
     9481 aactgtttcc ctattcagtt ttgcttttcc tttccgtttc atgtagcttt ctatatcaaa
     9541 taaatttttc ttatcatagt cctcaagcag cttatagttc ttgtgctttg taatatcgta
     9601 cttatctgaa agaaaaggtc tgacacctct aagctgaaag atacattttc caccatccat
     9661 gaccgtaatc tcatcctgac tcatcagctc tttgcctgtt ttttgatagt taagtccaaa
     9721 gctcttttga tttgaccttg tttccgatgt gttgtaaagg tcgatagttt ctttaccaag
     9781 cgtttcggac agctctttta gtgttttttt cctttccacc taagaataag gtactatcac
     9841 agttacccac aatggtatca gcattatcct tatatattgc ctttagctga gattgtgcct
     9901 gtaagataat actcgctgaa atttctctac ttctaattgt ggctatgagc ttctcaaact
     9961 ttggaattaa gccgatattt gcaaactcat caagtaagca tcttacatga acaggaagtc
    10021 tgccaccata tacatcatcc gccttatcgc aaagtagatt aaataactgt gaatacataa
    10081 tagacactac aaagttaaag gtatcatctg tatcagagat aataacaaag agtgctgtct
    10141 ttctatctcc caatgtatca agctcaagtt cgtcttcact catcaaatct ctaagttcct
    10201 gaatatcaaa tggagcaagc cttgcaccac aagatataag aatagatttt gctgtctttc
    10261 ccgcagccaa tttatatttt ttatattgct tgaccgcaaa gtgcgtaggc tcctttttct
    10321 caagtgcttc aaagagtctg tctattggat tcatataggt ttcatcatct tctcttactt
    10381 ctgaagcgtc tatcatatca aggagcgttg caaagttctt ttcttctctt ggagcttcat
    10441 agaagatata tccgataagt gctgtgtagt agagtttttc cgctttgacc caaaaatctt
    10501 cacccgcttt ttctccctca ccttttgtat ttgcaatgat tgtctgcact aatttgagta
    10561 tatctttctc agaatggata taggcaaagg gattgtattt catgctcttt ttgaagttta
    10621 tggtatttag aatttttatc tcatatccat tgtcttcaag catcttgcca cattcaatga
    10681 ctatcgttcc tttcggatcg gttacgcaat agctactgtg catctgcata aggttcggtt
    10741 ttacataaaa tcttgtctta ccacttcctg atccaccgat tacaagtaca ttcttgttac
    10801 gagcatactt tggattagcc ggtctaccat tcatagttag gcgttctgtc tgggtaagca
    10861 agatattgtt ttgaaacttt tcatccatgt atggctcaat atctttctta tttccccatc
    10921 ttgctgagcc atactctttc ccctgtctaa actttttagc attttacctt tggtatagac
    10981 aataaattta attaaagcag ccattcctat gcccattaaa atatccgccg gatgaatact
    11041 tggaagaaaa ctcatcgtgt tgatctccaa tatcccttga aagattttat ctatgacatc
    11101 accaccggta tagcttctca catgatgggc aaagatgttt cctaaataga aaaatgcaag
    11161 atagggaatg ttttgcttta caaactttgt cttatcctgc accttaaata agcctttgat
    11221 gtcctttaat attttatcta tcataggctc tgctcctttt gtttattctt gattttatct
    11281 ttggaaacag agttcttagc catttcctta aacttctcaa tattcttgtg aatagattct
    11341 ttcctttccg ttttcttttc agactgtgct aatgcgtgct taaaggcttt atccatcact
    11401 ttcatatctt tggcttgaaa gaatacagag tattttcctg tttccttatc cttcatcact
    11461 gaaaacttaa caccataccg attaagttct tttttcagtt ccttaagctc cgcttcttca
    11521 acaggaattt cttcaagctg tccctttttt accatatctt ttagctttac ttcatttccg
    11581 ttagcattaa ccagcttttc aagtcctcca agtttttctg cttctttcat caatttcttt
    11641 aataagttca gaattaactt tcctgttact ttagcagctc ttacttccat attcagcgtt
    11701 tttcttgcta tttcttcatt gatcaagttc tctcacctcc attcagtaac ctatctttat
    11761 ttcgattcaa tttatctctt tgaataatct ttctaaaatc ctctttggat tgtgtcgtag
    11821 gaaaggttag tggtgaagat agtcggtttc tgctttaagt acctgttgtt gacaatgtta
    11881 tatacctgct ctttggcata gcttgtatct ctttctattc ccaagtcatc caagataaga
    11941 acggaagtat ttacaaggga ttcaatatat gcgttcttat caaaatcaaa tcctcccttt
    12001 tgcagctcat tgataagctg tgcaaaattt cttattttaa cgcctatttg atactgttca
    12061 ataaggctat ttgcaatgga gcaggcaaga taggtttttc cacttcctac tgagccgtaa
    12121 aatagcagtc cgatattttc ttttttcatc tgctcatagt cttttacaaa attctttgca
    12181 atgataagac tttgattttc ttctccctga taattttcaa aggtgtatga ccactgaata
    12241 atagagttaa agcagttctt ttttaatcgt tctatttcca tctgcttttc tctttctttt
    12301 tttcttgcct ctctatctct atcgcatttg caagaaatct taaatatcat cttgttatca
    12361 aagaactcca tcacttttct gtcttttctt tcatgacaaa ctttacaaaa ggcgtgtccg
    12421 tccttgatat attctttttc aggatcgtaa gaatactcta catcctctat cattactttt
    12481 tctaattctt ttatcatagg tgttctcctt tatcatattc ttcccatgtc gggatatttg
    12541 atgttttcac ttctttgccc cttccctgat ctttataaaa ccatgaaagg attgttgcct
    12601 tatggtcttt ataggtcttt ccggtgcttt taatatatgc agataatctc tcaatataat
    12661 tatcaagctg tgagttcatt atgatttgta agtctgatat atcttcagca gctaaaaaca
    12721 cattttgaaa tgttccaagc ccgttttcac taaaattata ttctctctta ctatacttac
    12781 tcttattatt ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt
    12841 tacttctgag gttaaaatct tttacttctg aagtaaaatt ttttaacttc tgtaagtcat
    12901 cttcttttac ctgaaatatg ctcataaaat ctttgacata aatgatattc ggctttccaa
    12961 gtccaagccg tacccgttca atcagtccaa ttcctttttt actatctaat tcatctaatg
    13021 tttttatggc agtcggcttt gagatatttc ttcttttcat aatttcttcg actgtgaaat
    13081 agataaatac cctgccttcc ttatcaatcc agttattctt aaaggacatt cctgtccgtt
    13141 taagaagcat tgaataaagg ataattgctt cagcggataa tcctttaaat tcttctccat
    13201 caaccaatat ctccggtact tttaagaaat taaatctttc cgcttctctg ttataaaaat
    13261 agtcaaagtc catcgcttca cctccctcct taaaaatttg caaagaaaaa gacgatagtt
    13321 tttctctatc gcctttggta accattttta tgaaattttt tagattgatt ttattgcttc
    13381 attgattcct ttaaagaatg ctataactgc tgctccaacc atcggtattc cataaggact
    13441 taacaaaaat cctaatacta atgcctcaat gccaagtgat atatcttttt gcataaatga
    13501 tcctattgca gcaactatac acatcagcat taagaaatac agaatagttg ttcctatgcc
    13561 aagtataaat gtcagaaagg cagtaaggac actaagtagc aagctgaatg gaaacaatat
    13621 tatttttatt atccacctca tataatacct ctcctttctc ttaaatcatt ttaaagtgcc
    13681 ttaacgcatc cataatagct ttttctttct caggtgtaca ctgcggaata acttgcttat
    13741 ctttttttga tttattgtaa ttctctctaa gttctattcc acattttctt tttatctgtg
    13801 ctatatatag tgttgaaact ttaaaaccaa atttttctaa tatatactct ttaattttag
    13861 cataggtagc cttgctttct gcacttgtca aatcaagttc atcaagctct atttcaacac
    13921 ttatatactt atcgacatta agtttggaca ataatgctac cgtctcgaca tgatgtgtca
    13981 ttggaaacaa gtctactggc tggactttct ggagtttata gccgagttcc tcgtagcgct
    14041 tgatgtcacg cgccatggtg gcggggttgc aggatatata ggttattttg tcaggctgca
    14101 tcgctgcact ggccttgata aagctctcag ttagtccctt tcgtgggggg tctacaatga
    14161 taactgttgg ctttatgccc tcctgacacc agtttgccat cgcattttca gcgctgtcag
    14221 cgacatagta ggcattggta ataccgttta gcgctgcatt tttctcggca tcacgcactg
    14281 ctgcttcgat cacttcgaca ccgtatactg ctttgacttc tttagcaaag gatagcccga
    14341 tggttccaat gcctgaatag gcatcaatca ccacatcgtc agcggtcaat tcagaaaaat
    14401 caatagctgt ttgatagagc ttttcagcca ttgttgtatt gacctgatag aaggactgag
    14461 cagaaataca gtattgattg cccaagatcg tatctgtgat tgtctctttt ccataaagcc
    14521 ttgtaaacgc cttaccaaag ataacattag taggcttgtc attgatattt tgcaggatag
    14581 aagtaatcgc tggaaattct gcgacaaggc tatcaatcat ctggttgata cgaaagattt
    14641 taggtcgtgt tgtcactaaa accagcatga tttctcctga ataatgccca cgacgaacca
    14701 caagatgacg aatcaggcct gactgctcct tttcgtcata gggcttgatg tcaaaacggc
    14761 gcaaaaggtc gcgtgtaaag gcaatcaagc gatcaatttc cttatcttga atgtaaaaat
    14821 cagaaatcgg cactagctca tgagaatgct tacggaaaaa accagtctct agctgaccat
    14881 tgacacgacg aacaggaacc tgggctttat ttcgataagc ataaggatat tccataccaa
    14941 ttgtttcttt gacctcaaca ttgctaatcc ctgcaatctt atagagacta tcctgaacct
    15001 gcttttgctt aaagagcagc tgctgcggat aaagcaagtg ccccaaatca gcaatacctg
    15061 tacgcagata ggtcacatcc agcttttttt gacgcatcgg tgaggttgtt agataggtct
    15121 ctaccttgcc aaagccactg tttttattga cctttaggac acgcatctga atgatctcac
    15181 ctggaagagc attttcaaca aagaaaacaa agccttcatg cttagcgatt cctaagccat
    15241 catggcttaa atcagaaatt tccacctgaa caatatcgtt tttacttaac atttactttc
    15301 cttttctttt actacactaa tcactcaaaa aagaagagca accatcgtta cccttcatta
    15361 tagcatatct tagcgtaatc ccagcttaga taatcgattt tgatacttag caaaatcaat
    15421 aaagagagcc tgaccaccat acatgtcata ttcatcaatc caatccccat tttcaggaat
    15481 cgtcacatgc tccacaccgt ttttgccatt agtcaagacg gacactccat ttttaaggac
    15541 aaatgggaag gagacattgg ttgaggttag ggcataaatc ttaccaatag ctgctgagcc
    15601 cgtaaagagc ttggttggat ccttgatttg agacatgata gcagccatca cctgctgctg
    15661 acgtacggtc cgaccaaaat caccctcatc gtcctttcgg aagcgagcat agttgagcag
    15721 ggtacgacca tccatttttt gctcaccaac cgttatggtt tggttgggaa ccactccgtc
    15781 tttcattcgt aaatcatctg gtacatcaac agcagcgact gcttcgccat ttacagtagc
    15841 aaatttggca tcaatggtaa caccatctgg aaacagtgtg tcaatagcct cagcaaaggt
    15901 ttcaaagtca accatgacat aatatttaat gtcaatatca aaattatgct tgagtgtctg
    15961 acgcacaaat tctgctcctt gatgattttc ctgctctcct aaattaaagg aggcgttcaa
    16021 ttttaaatca taggaatcct gattattata gctatagcca ggaatattaa ccaaggtatc
    16081 cctcatgaag gagaccattt tgattttatt ctccttattg ccaacattaa ccaccatgat
    16141 tgtatctgtt cgagcatctg ttgagccttg cgtaatcctc tggtctgagc ctagaattaa
    16201 aatattagtg ccatcgctag tatcctgacc atgaaagacc tgcgaaactg ctggcttata
    16261 attggccttg ttagtagaca cgtccatcat tcccttgaaa aacatgaaag ctatccctgc
    16321 aacaagcagc agcaacaaga aaaagagtat tctgaaaaaa cgtctcagac gtcccttctt
    16381 ttttttcctt ctaccctttt taggcatagc ctcaggcgca agctcctcat agatcgcctg
    16441 atctgggtca tcatagaagt cctgctgagg ggctagtatt ggcttttgct gatgcctttt
    16501 gctacgtctt tctgatcttg gataaagagg caggccatta ggcccagcct gctgctcatc
    16561 actcatatca taagcatcag cattatcctg tgaagcttga gcataatcgt cacgcccacc
    16621 cctagtataa tgagtcaagg agcgctgaga acgagaaggc atagcccttg actccatctt
    16681 tgactttaaa aaggtaaatt ctctgcgttc agtctcagtc aaataattta aatttcttaa
    16741 taaataaaaa tatcgtaatt cttcgtggtg gcttagacca cccttttggt atctcgtcat
    16801 gctcttccaa ctcttagtat tctaatacaa tttcttctat tctttgtcta atgattctat
    16861 tataacctat attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc
    16921 tatatattag cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa
    16981 aagtctaatc ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt
    17041 tctatgctca acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg
    17101 aaaaatagca tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct
    17161 atctttttta agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt
    17221 gtgatttttt ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga
    17281 tacgatagtc tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct
    17341 aaaggctgct tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc
    17401 aataagccta tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc
    17461 aactcccata aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa
    17521 agtcaggata agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa
    17581 ccagtagggc tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag
    17641 ctgcaccatg taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat
    17701 cagcacccat ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc
    17761 gtaattcttg agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa
    17821 taacaggcaa ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta
    17881 gggtggaata agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg
    17941 agatacgacc acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc
    18001 ctacattttc gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg
    18061 ctgcgctaga gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt
    18121 tgatactgat ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt
    18181 cggtatgatt tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag
    18241 cagctaataa aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg
    18301 gccgcaactc ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag
    18361 atagctctgc tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata
    18421 ggctatcatc tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca
    18481 ggcgcataga agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt
    18541 taaaacctct tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt
    18601 ctcgaaaggc ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg
    18661 tttgcccctc tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg
    18721 gtacccttag acgtccccta agcgccttag cttttgtttt taatttcatc attactccta
    18781 tttttagtac accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag
    18841 ggcccttacc ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc
    18901 gctatttctt gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat
    18961 tgccgctgcg cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg
    19021 cccccataat caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca
    19081 ccgaaccaaa ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa
    19141 ccatattgct caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc
    19201 tgattttctt gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata
    19261 taatcagtat cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta
    19321 agtgataatg cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg
    19381 caaaggtcaa caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca
    19441 aaaagtcacg atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta
    19501 ggcttcgcga cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg
    19561 gcttagaaaa aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct
    19621 gctccttcat taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag
    19681 ccgcaatgac aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg
    19741 acaaatccat ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc
    19801 attttgatat gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg
    19861 ccctgactag ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg
    19921 caggacaagc caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt
    19981 tcccatgtgc cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt
    20041 agtcctcttc ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca
    20101 acaccatgac caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg
    20161 actgctgcac caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac
    20221 atggcttcct tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca
    20281 taagcccagc aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct
    20341 gccacattat caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt
    20401 agcaccatat ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca
    20461 tgtgcaacct catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca
    20521 tcaacaccga tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct
    20581 tcgacctccc acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca
    20641 gcaagaaagt ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc
    20701 attgtttttg tttctcctct aattaagctt agttgtaata atggctttag caatcacctg
    20761 atcatcaacc atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt
    20821 agggtatatc ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg
    20881 ctcgataatg atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa
    20941 gaattcagca accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat
    21001 catgacctga taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt
    21061 gtaaagattt cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat
    21121 ccccagcaga aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat
    21181 tttttgacta atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat
    21241 cacctgctca agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc
    21301 aaccacctga tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag
    21361 tgcattaaat tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat
    21421 cagaacctga gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt
    21481 aatcatcgtt gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct
    21541 atcagctgtt tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt
    21601 gtgattttta agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc
    21661 tttgatcaaa taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa
    21721 ctcatgtccc aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc
    21781 ggcataggtc aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact
    21841 acgcggcttg gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt
    21901 accatcacta acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc
    21961 aagtctttct aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg
    22021 ttagttgata ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt
    22081 gctttgttaa tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat
    22141 gtgtcacaat gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct
    22201 ttaagacctc ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct
    22261 cagcacttgc ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc
    22321 tggtcttatc ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta
    22381 agaaatcact ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat
    22441 gactgatcat atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc
    22501 gttgcgtctc aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt
    22561 caacatgcct gtaatactat tattatagca gatatcacct aaacattcta taactgtcat
    22621 gagttttgcc atgatgatca taataacctg acaagccata tcatagctca atcagactct
    22681 aagctgttaa actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc
    22741 ttgctatctt atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag
    22801 ctcatccttc taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt
    22861 tgaagtcact gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa
    22921 tggattagcc ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt
    22981 agctggtgct gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt
    23041 ttctggatca gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc
    23101 gtcataagcc cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc
    23161 ggctgtggct gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat
    23221 aacaagccta taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac
    23281 aggctgttca gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac
    23341 accattttta ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt
    23401 agtagctgtt tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc
    23461 tggtgttagt tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc
    23521 cttaagcgca ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc
    23581 actaatgcca tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc
    23641 tcctgtaatg tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac
    23701 tgaagcagca tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc
    23761 gcttttgtgc tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc
    23821 aagctgaaca ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac
    23881 agtatctgca gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt
    23941 gtcagcgtag tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt
    24001 tgtaggctct aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa
    24061 ggctgccgac actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt
    24121 gtttttttcc atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaacta
//
LOCUS       DARYVE010000025        23590 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYVE010000025 DARYVE010000000
VERSION     DARYVE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23590
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            85..366
                     /locus_tag="TVW25_000984"
     CDS             85..366
                     /locus_tag="TVW25_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1378625.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TVW25_000985"
     CDS             complement(492..917)
                     /locus_tag="TVW25_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1378626.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TVW25_000986"
     CDS             complement(914..1318)
                     /locus_tag="TVW25_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1378627.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TVW25_000987"
     CDS             complement(1340..2119)
                     /locus_tag="TVW25_000987"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1378628.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TVW25_000988"
     CDS             complement(2116..3048)
                     /locus_tag="TVW25_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1378629.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TVW25_000989"
     CDS             complement(3326..3598)
                     /locus_tag="TVW25_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1378630.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TVW25_000990"
     CDS             complement(3662..4099)
                     /locus_tag="TVW25_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1378631.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TVW25_000991"
     CDS             complement(4086..6218)
                     /locus_tag="TVW25_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1378632.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TVW25_000992"
     CDS             complement(6386..6712)
                     /locus_tag="TVW25_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378633.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TVW25_000993"
     CDS             complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TVW25_000993"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1378634.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TVW25_000994"
     CDS             complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TVW25_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1378635.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TVW25_000995"
     CDS             complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TVW25_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1378636.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(9483..10355)
                     /locus_tag="TVW25_000996"
     CDS             complement(9483..10355)
                     /locus_tag="TVW25_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1378637.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(10514..11839)
                     /locus_tag="TVW25_000997"
     CDS             complement(10514..11839)
                     /locus_tag="TVW25_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1378638.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(11823..12545)
                     /locus_tag="TVW25_000998"
     CDS             complement(11823..12545)
                     /locus_tag="TVW25_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1378639.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            12717..12872
                     /locus_tag="TVW25_000999"
     CDS             12717..12872
                     /locus_tag="TVW25_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378640.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            12913..13815
                     /locus_tag="TVW25_001000"
     CDS             12913..13815
                     /locus_tag="TVW25_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1378641.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            13815..14630
                     /locus_tag="TVW25_001001"
     CDS             13815..14630
                     /locus_tag="TVW25_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1378642.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(14815..16236)
                     /locus_tag="TVW25_001002"
     CDS             complement(14815..16236)
                     /locus_tag="TVW25_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1378643.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(16263..18125)
                     /locus_tag="TVW25_001003"
     CDS             complement(16263..18125)
                     /locus_tag="TVW25_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1378644.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(18130..18969)
                     /locus_tag="TVW25_001004"
     CDS             complement(18130..18969)
                     /locus_tag="TVW25_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1378645.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TVW25_001005"
     CDS             complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TVW25_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1378646.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(20715..21542)
                     /locus_tag="TVW25_001006"
     CDS             complement(20715..21542)
                     /locus_tag="TVW25_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1378647.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(21543..22340)
                     /locus_tag="TVW25_001007"
     CDS             complement(21543..22340)
                     /locus_tag="TVW25_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1378648.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(22858..23367)
                     /locus_tag="TVW25_001008"
     CDS             complement(22858..23367)
                     /locus_tag="TVW25_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378649.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            complement(23364..>23590)
                     /locus_tag="TVW25_001009"
     CDS             complement(23364..>23590)
                     /locus_tag="TVW25_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378650.1"
                     /translation="VQRVAIARMLMKPRKIILADEPTGALDSEIGKEIINLLLSETAE
                     NKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
BASE COUNT         6782 a         5599 c         4428 g         6781 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatgac
     6721 tcctatttgt ttttttatgt agttattata taatattaat aagattatag tttactaata
     6781 tatatatata tatatttcta ataccagtaa cctttgtctg aaaatagcta gatcgtgctt
     6841 atcaaagaaa gcaaaaaagc ttcactctac aggaagtaag agagaagctt ccacgctaat
     6901 aggatactga tctgacatca tcaaaacacc aattgaggag agatttagcc ctcattccaa
     6961 ttgctctttc atcgcctagt ccttttctta tccgaagcgt ccggaaatat aatcctctgt
     7021 acgcttgtcc tttggctttg taaatagttc agctgtatcg ccaaattcac aaatatctcc
     7081 tgtgaggaaa aaggctgttt tatctgacat gcgtgaagcc tgctgcatgt tgtgggtaac
     7141 gatgataatc gtgtaatcct gctttaattg ctgaaccaag tcctcaattt ttaaggtaga
     7201 aatgggatca agagcagagg taggctcgtc catgagcaac acatcaggtg ctacagcaag
     7261 cgctcttgca atgcaaagcc gctgctgctg tccacctgat agggacatgg cactcttttt
     7321 taagctgtct ttgacctcgt cccaaatggc tgctcctctc aaggactgct ctaccagctg
     7381 atctagagtt ttcttgtcct taaggccatg tgtcctagga ccataagcca cattatcata
     7441 aatagacatg gcaaatgggt tgggctgctg aaagaccata ccaacacgct tacgcagact
     7501 gttgaggttt attgctttag catagatgtc ttgattgtct aagagaacct ctccttcgat
     7561 acgacaggaa ggaatcaagt cattcatgcg atttagggtt tttaaaaagg ttgatttgcc
     7621 acagccagag ggacctatca gggctgtgat ctgattttct ggtatgtcaa tggagatatc
     7681 ctttaaggcc tgaaatgctc cataaaagac attaagctgc ttggttgaaa aagctcccat
     7741 tttagacgac tcctttcact aatcggcgtg ataataagct tgatagggca ttgatcagca
     7801 agacagttat gagtaagata acacccgttg cataagcttc cttgacatgt agcccttcgc
     7861 tagacagcat gtacatgtga agagctagtg agcgtcctga tgacatgagg ctggttggcg
     7921 tattggtaga ggtgcctagg gtatacatca gggctgctgt ctcacccaca acacgtccaa
     7981 tcgctaggat taccccggct agaataccag gcattgcagc cggcagcact attttaaaaa
     8041 tcgtccttag cttacctgct cctaagccaa ggctagcctg acgcaagtga tcactaacag
     8101 agaggagcgc ttcttctgtt gatcgaatga taactggcaa caccatgatt acagacgtca
     8161 gaatacctga taaaagagaa tattgcaggc cgaaaaaaac cacaaagaac agcatgccaa
     8221 aaagaccaaa aacaatcgaa ggaatccctg atagcgtatc agctgcaaga cgtattgccc
     8281 ttacccatag tgagtcctgc ttagcgtatt ccacaagata gaagccagca aagacaccaa
     8341 tgggcaaggc tagcactaag gtgcctaaaa ctagactaac agttgagata atcgacggca
     8401 ttagagaaac attgtcagag gtataggtcc atgaaaataa ggataacgac agactaggca
     8461 agccttttat cagcataaag gcaataatca aaaataagga gccaaaggtc aatagcgaca
     8521 aaagatagac cagggctttt agtaaatagt tagtcatgag ctgattttcc tttcacataa
     8581 gcaaagcaag cattaatgat gagaataaag ccaaagagga cagccgatgt tgcaatcaag
     8641 gcctctctat gctgaccaga agcatatgcc atctctagga caatatttgt cgtcatggtt
     8701 cttgtgccct caaataatcc tgatggcagc acaggctggt ttcctgctac caaaataact
     8761 gccatcgtct caccaatggc acgaccaaat cctaaaataa gagcggaaaa aaggccggat
     8821 ttggctgctg gcaggatcac tcgaaaaata ctcctttcat gactggctcc cagtgcaaga
     8881 ctagctgaat aataagcctt tggaacagct ctgatagcag actctgaaag actgataagc
     8941 gttggcaaaa tcatgattcc taagagcaag gaggcagtca gcacactcat gccattacca
     9001 gcaaagctcc taatccaagg cactagcact tgaagaccaa aaaagccata aacgatagac
     9061 ggaatggctg ccatcagatt aacagctgac tttaaaaagc catagcatgc tttaggacaa
     9121 tagtaaacca taaaaactga ggtcaatata cctgttggca caccaatcac cattgcacca
     9181 agtgtgatga caaaagaccc tgcaatcatc ggcaaaatac catagcttgc cggctgattt
     9241 gacggtgacc aatcatttcc tagcaaaaag gctctcatac catacttagc aataaaggga
     9301 aggccattac taaaaataaa gatacagatt aaacaaatag caataattgc catcgctgca
     9361 ctgagaaaga agataacttt aaaaaaatcc tctttaaagg cttgtttatt cactgatgat
     9421 cctttctaag aaaggaaagc aagaacaaaa cacctcttct ttgccttcct tctaatcgtt
     9481 ctttatttga ctttgtccca gcttgttagc ttgccgctaa agacatcagc cagcacatct
     9541 atgccaatat tacttacctt attgtccttg tgaacaatca ctacgatacc atcaagggca
     9601 atcgcatcat caattaagcc cttgctctcc tcagttgtta ggtcacgaga aaccataccg
     9661 atgtctgctg ttttttcctt gacggcggtg atacctgctg atgagccatt tgaggtaata
     9721 tcaatgctaa tggctggatt ttctttcttg tatgcttctg ctaatttttc catcaagggt
     9781 gaaactgagg ttgagcctac aattgacagc ttgcctgata agcccttact gctataggct
     9841 ggcgcgtctg tttttgcttc gatcaatcga ttgtctctaa caatctcctg cccctgcttt
     9901 gagtcaataa aggtgataaa atccttacca actcctgata ggtctgagga ccatacaata
     9961 ttaaagggac gctgcagagg gtatttcccc tctaaaatag tctcacgact agcctttacg
    10021 ccatttacct ttagggctgc aacgtcgcta tttaaggacc ctagcgagat gtagccaatg
    10081 gcacgactat ttcccttaac agaggagatg accccttctg tgctattttg gataatagct
    10141 gtttttgctg tttggtcaat ctctttgtca ccgtcctttt ttagaatgcc tgtcatttcg
    10201 gtaaaggctc cacgagtacc tgagccattt tctcgagaaa caaggtcaat cctgtctgct
    10261 gcttttccag catcagcact gttattgcca caggctgcaa gacctaagcc tgataagcca
    10321 atagctgcca tgatcagcat ttttttgatt gtcataagaa tcacccttat cttttatgat
    10381 attgtgttgt aggcttgcta cacctatagc ttatcaggtc tttgtaaagg tttatccctg
    10441 attaatgtaa agattttgta aaacctaaaa cagccactac caaggctggc cttaagtagc
    10501 tggtagtgac tgtttacttg ttgatagctt ctggtaagaa taaggtaaat tggctgccct
    10561 ctcctagctg acttgtgact gttatctgac cgccaagaag ctgactcagc tcctttacaa
    10621 tggctaggcc taggcctgtt ccaccacttt gcctgctacg tcccttgtta acacgataaa
    10681 agcgctcaaa aatacgatct agctcaattt ggctaatgcc aatcccagta tctgcaactg
    10741 taatggcaac accaccagca accctttgac tggatagctg aattctgccc ccattgtctg
    10801 tatactgtat cgcatttgat aagagattta acatgatctg cgataagagg tattgatcag
    10861 atgtcacaac aatcgaatcc tccaatgcat agcttagctc aagctgcttt tgctctagct
    10921 gtggcctcat gctctgacct gtatacagca ggaagttcct gagctgaaac tctgtcaggt
    10981 caagtggtgt cttgttagcc ttggataagg tcagcaggtg ctcaacaata cgttctagac
    11041 gcaagctttc attgtagata atgtctaaaa agtcttcttt taggcttgtt tcatcgtcag
    11101 gcatttcctt aatcgtttca gcaaagccct tgatcgatgt aaccggtgtt cttaattcgt
    11161 gagaagcatt agcaataaac tccaaattta gcctctcata atgacgaatg gccgtcagat
    11221 catataagag cactaaaatc tccttgacaa catgcgactg gttaaagata ggcacaaggg
    11281 taacctccaa gatcaaatca ccatcatgta ggcctgttaa ttccttcttt aatgtctgct
    11341 tttggtcaaa gacttgatta actaaggcta tcagatccat tcgtttaaga tcctccaaga
    11401 ccacaaaagg tggcttagcc tctggaaaat aagccggtaa ggatttgctg gtcagcaaca
    11461 gctccctttg attggagact aaaagcatgc ccatcgtgag atgagaggtt acagcctcca
    11521 cattttttga taaggctttt agccttgctt ccttttgtaa taggtcactt tttagctctg
    11581 tcagctgctt agcataagca cttaaatcag cctgccccac taggagaaaa tggtcactag
    11641 ctgtcaaaag atggtggtgc aaggctctga attcacgctc ccatctaaat agcatgctca
    11701 agacataaaa gctagctacg agaccagtac acagcactac tagagtcagc acctgatgcg
    11761 gcccttgcca aatcagacca agagcagcca gcaagcaaag ccctagcagc atgctcaaac
    11821 gcctaagatg tcctatcatt ctttagctcc ttaaatttgt agccatagcc gcgaatggtt
    11881 tgaatatact gaggcgcctt aggattgtcc tcgatttttt ctctgagctt gccaatatga
    11941 acgtctacca gacgtgtttc ttggccaaag tcataacccc agatacgctc taatagccgc
    12001 tcacgcgtca gggtcatatt agggtgcttc atgagataga gcagtagctc atattccttt
    12061 ggggttaacg gcaatagctc cttgtcctta tagacctcat gtcgctctgg gtacagacgc
    12121 aattgactca tcgtataaaa aggctcacga cgctcttcac catcaccaga aatctctgct
    12181 tcagtacgcc ttaaaatagc cttgacacgc gctaataatt ctctaggact aaagggcttg
    12241 gtcacataat catctgcccc cagctccaaa gccaaaacct tgtcaaattc atcactttta
    12301 gcagaaacca tcataattgg ggttttgctt cccttagcac gaagcctttt gcagacctcg
    12361 ataccgtcta attgcggcag cataatatct aacacaataa aatcataagg ttctctttca
    12421 gctaatgcca aggcagtacg gccatctgtt accatctctg tcacaaagcc ctccttggcc
    12481 aagtgataat ccagtagcct taagataggc tcctcatcat ctactaataa tactcgtttt
    12541 gtcatttcat agctcccatc agccacatta tatcatattt gtcagtcaat ctaatgacac
    12601 actgcttgac ggcctgaagc ctaaaatcaa tcagaagata aaaagatgtt ttagctttgg
    12661 ctttaccgtc aaatgattgt ataatagagc tatattgatt gaaagaaggt atacctatgg
    12721 caattactca taagaaaaat gaccagctcg aaaagatgat ggcaggcttt gcgtctatcc
    12781 cagattttga taagccttta gagcttaacc aagatggaaa gctagtcact gaaaaaccaa
    12841 agccacaagt caagacagct aagcaggact agcccttatt ggcgtcgtta acatatagaa
    12901 aggatacggt gaatgtcgct tttttcaaat ctgccaccca gcgtgcttca atggtttgcg
    12961 atttttctat ccattatcat tgaagccctg ccttttgtat ttttagggac tattttatct
    13021 ggctgtattg aggttttcgt cacgcctgat ttagttcaaa gatacctccc tcaaaataag
    13081 tggctaagaa ttttatttgg tacctttatt ggctttgttt ttccttcctg tgaatgtggt
    13141 atcattccta ttattaatcg ttttttagaa aagaaggtgc ctagctacac tgctgttccc
    13201 tttttagcaa ccgctccaat tattaatccg attgttttat ttgctaccta ctctgccttt
    13261 gggaattcgc tgcgctttct catgctaagg cttttaggcg ccattttagt ggctgtcagc
    13321 cttggcatca tgctagcctt cattgttgat gagaacattc tcaaggaatc aacccagccg
    13381 gtgcattgtc atacttacag tcacgaaagc ctgccaaaac ggctttactt ggcactggct
    13441 cacgctattg acgaattttt tgatacagga aggtatctag tctttgggac cctgattgct
    13501 tcagccatgc agatttatct gccaacaaag gtgctgacag cgatcggaca tagccctttg
    13561 acagccatct tagtcatgat gctcttagcc tttatcttat ctctttgcag tgaggctgac
    13621 gcctttattg gagcttcgtt attgtcaacc tttggagttg ctcctgtttt agcctttctc
    13681 ttaatcggcc ctatggttga catcaaaaac ctcatgatga tgctcaattc ctttaaggga
    13741 gcctttattg ttcaatttat cagtgtatca gctgtgatga ttaccatata ttgcttactt
    13801 gtgggggtgc tgtgatgatt cgctttttaa ttttagcagg ctattttgag ttgaccatgt
    13861 atctagagct atctggcaag ctaaatcaat atatcaatat tcgttacgct tacttagcct
    13921 atatttctat ggttctatcc tttatccttg cattggtgca gctatacact tggactaaaa
    13981 acatcaagct acacagtcat ttaaaaggta aggtcgctca gctgaccagt ccccttatcc
    14041 tggtctttcc tgttttggtt ggcttgttag tacctacagt cagcttggat tcgacgaccg
    14101 ttgccgccaa gggctatacc tttccattag ccgcaggcgc ttcaaaaaca ggggtcagtg
    14161 atgatggtac tactattcaa tacctaaagc cagacaccag cctgtacttt accaaatccg
    14221 cctatcaaaa ggaaatgctc aatgaactga aaaaatacca aggcaaatca gccatcacca
    14281 ttaccactga caattatatg gaggtaatgg aattaatcta cctttaccca gacgaattcg
    14341 ttgatcgtac gattcagtac actggctttg tctataatga gccaggacat gacagctatc
    14401 aattcctctt tagatttggg attatccatt gtatcgctga ttccggtgtg tatgggcttc
    14461 tgaccactgg taatcaagaa agctatgcca ataacacttg gctgaccgtc aagggccagc
    14521 tgcacatgga atatgacaag accctagagc agcagcttcc tgtccttcaa atcgaggaag
    14581 cacaccaagc cccagagcct gataaccctt atgtctatag ggtattttaa caagcattaa
    14641 gcctccacac ctatgacaca ggtctatgga ggctttttgt taggggacag tacaaagacg
    14701 taattgagtt cgttccattt aaatgaaatg gctaaaagcc gtatagcatc agccttttaa
    14761 aagacgtgtg ctatacggct ttgctattgt tggtaaagcc tttgaggcta ctttctagct
    14821 ctcctcagac aggctacgcc cattggtctc aatgaccctt tgataccaag caaaggattt
    14881 tttcttgtag cgtgtcaaat gaccactgcc atcatcatgt cggtcgacat aaataaagcc
    14941 ataacgctta cttagctgag cagtcgacat agaaacacaa tcaatacagc cccaggaggt
    15001 atagcccata atgtcaacac cgtcctcaat agccttagca acctgcaata aatgctgcct
    15061 catgtaatca atccgataat cgtcctgaac tgtccagtga ccatcctttg tctgtactag
    15121 cttatctttg gcgccaagcc cattttctac aataaagaga ggaatttggt acctatcata
    15181 gtaatcattc aaggttatgc gaaggccaat tggatcaatt tgccagcccc attccgaaga
    15241 gggcagatga ggattaacca agccacctaa aatattgccc tcccctcgtt gataatgatc
    15301 cgggtgatga gactgagtca cactcatgta atagctaaag gataaaaagt caaccgtatg
    15361 ctgcgccaaa agctcactgt cgcccggttc aaattgaatg tcaatgtgct gctccttaaa
    15421 aaaggatttg gcataggaag ggtattttcc tctgacctga atatctgaga acaggagatt
    15481 acgttgctca aactgcttcg cagctaaaat atccctcgga tcagaggtca ttggataggc
    15541 tggcatagcc aaaatcatac agcctatttt aaaagcaggg ttaatcaatc tagcaagcct
    15601 tgtcacacta gcagacgcta ctaattcatg gtgaatcgct tgataaagct cctgcggagt
    15661 cagcttttcc tttggtgtca tgatagcacc actggtaaaa ggcatatgca ggattgaatt
    15721 aacctcattg aaggttaacc aatacttaac cttgttcttg tagcgctgca tgacagttgt
    15781 cgcaaaacgt tcaaagaagc caaccatacg acggtcagtc cagccattat agaccttagc
    15841 tagatgcagt ggggtttcgt agtgagatag ggtcactaaa ggctctatgc catgtgctat
    15901 cagctcatca aacaaatcgt cataaaattg tagccctgct tcgttaggct ctgtctcatc
    15961 gccctgagga aaaatacgag accaagcaat tgatgtccgg aaaaccttaa agcccatttc
    16021 tgcaaagagc gccacgtcct ccttgtagcg gtgataaaaa tcgatggcct ctagcttcaa
    16081 attagctgct gttggctcag ctgtatagtc tcctaagccc ccttctggta aaacatcctg
    16141 aaccgacaag cctttgccat ctgttaaata agctccctca acctgattgg cagcaactgc
    16201 ccctccccac aagaaatcct ttggaaaaca aaccatatta tctcctcctt caattcatct
    16261 ctttagagaa taacgagagc aacatcatgc tgagtgatat gctccttgtt gtcattaaca
    16321 atgatttcga gctgctcaga gctattggtc accacaaatg gagtcactaa agaatagccc
    16381 ttagagccaa tcaattcaag atctatacgt agcagcggct gcccctgctt aacagtatca
    16441 ccagccttaa ccagctgctc aaagccctgt ccttttagct caaccgtatc aataccaaca
    16501 tgaattaaga cgtcaactcc cttggcgttc tttaaagcaa tagcatgctt tgttggaaaa
    16561 agggtgataa cctcgccatc aaatggggca tagacatatt cctcattagg taaaatagcc
    16621 agcccctctc ctaaaagctt agacgaaaag gtttcatctg gcacctctga taatggaagc
    16681 actgtgccaa ccatcggagc ataaatagat tgctttgctg ataagccact ttttactggc
    16741 gtgctatccg agtcagctga cccctcctgg tcaacctcct catcaatgcc aaaaaaccag
    16801 gttaatgtaa aggttagagc aattgttaag cccgctgcaa ttaaggcatt ggtaaaatta
    16861 gcagagctag tcgggctaat gtattgtggc aatccaatta gtgatggcac cacaaaagta
    16921 taagaggcta tattaacaaa gccaatatag gcgcccacaa ggccaccaga aatcattgca
    16981 gcatagagcg gctttttaaa ctttagagta atgccataaa gagcaggctc tgtaattcct
    17041 gccaataaag ctgataagcc tgctgctaag gcaacctgac gggtttgctt ttgctttgat
    17101 tgacatgcta cagccaccgc tgctgatccc tgagctaggt tagaggctag cattgctggg
    17161 aggattaaaa catctggagt tgctacagag gccgccagaa aaataggagc aaaggcccaa
    17221 tgcatacccg tcataacaac aagcggcata attgcaccta aaatagcaag agccagccaa
    17281 ggagcaatat ggtaaatcgc tagcaggcta ttagacaagc cctgtcctat aataacaccc
    17341 agaggtccaa taacaactaa ggctagaaag cctgaaataa aaataatcaa ggtcggctgc
    17401 aggaagctct tcatcacact cggtacaaaa cggttaacct ctcgctcaat gtattgcatc
    17461 aggtaaacca taattaaaat cggaataact gacgcaccat agctagcagg tgtcaccggc
    17521 gctccaaaca aagccatagg tttacctgta gctaccatcg taacaaaagc tgggtgtagt
    17581 aaaatccctg caacagttgc tgctaataca ggtgtgacct taaagcgtgc cgcagctgaa
    17641 tatgcaatca tgattggcat aaaataataa gcagcatctc caaaaaaatt aataaaagca
    17701 actgtttgag agtccgtacc tgctagacca agcataggca ccaagatccc aaccaccttt
    17761 aacataccgc ctcccagtaa ggcaggtatc agtggagtaa tcacactagc tatcgtttca
    17821 atcaaccctt caatcataga ctgcttttga ccagcgctag agctcatatc agtttcatga
    17881 aactgtccta gggtcataaa tgccttataa taattgttaa catcgtttcc taaaataatt
    17941 tgatactgac cgttttggcg catgactcca atcacattag gaataagttt gattttttga
    18001 tctaccactt gtttatcatc tttcaaaacc aagcgtaacc gcgtgatgca gtgggttacc
    18061 tcttgaatat tctgctcacc accaactgct tcaaaaatgg ccttggctgt ttcttgataa
    18121 gtcatttcat tactccttca catttttgac taaacgtttg atatgaaccg ttaaatacaa
    18181 aagctcacta gagctaagct gataatggta tgcttttttc atgtgatggc taatttgcct
    18241 aacacagtga tattcctctg ggtatttatc cttaaccatc agcagcaaat cagtctcgtc
    18301 atcatcataa gccatgcctg ataacacgcg ctgagcaaat agcttcacat gagtgataaa
    18361 gcgataataa tcaatagaga cttcatcaag ctctgtctta aaatcagcct tgaccttctg
    18421 ttcaatgtaa gacacaattt ctgtcattcg atgaggctcc ttgaaaggat tatcaaggct
    18481 cgcgttgaca aagtgcatcg caataaacga agcttcatct acagccagag cgactcctag
    18541 ctcactggca atgacctcta aggccttaac gccaatcgca tattcatcag gataataccg
    18601 tctaatctcc cagcgcaagg gatcactaat gatcatcccc tgcttatgtc tttcaatagc
    18661 tgaatgaata tggtctgtca aattgatata gagtatttca tctaaatttt tacccagctt
    18721 aattttccct agattaataa gcctctctga gcaagcaacc acctcttgcg gaacagcaat
    18781 aaataattca gtaaaacggt tcatattgtc actatttttt aaaacaaatg acgcttcgat
    18841 agcttcacta tcgatatggt caccaattct tttcttaaaa gcaatcccct ttcccatcaa
    18901 aagaatatct agcccctgat ggttggtcga aatcgctgca ttatggttta aaacgcgttt
    18961 aataatcata aaagtcctag tccctcattg cttcacaata aaaaatgacc tatccacagc
    19021 atgctaaaag gccacactgg aataggtccc tgctcacaaa actgtgataa catcctttaa
    19081 tattctgatt catttgtcat tagcacgctt accctaagta atcacatcta ataacgtttt
    19141 cattttatca tctcctaaag gtcctgtcaa gcgttttcaa aaggctgttt gacatttgcc
    19201 tctaaacgaa ccccctcatt ctctttggcc aacagccgat aatctgaggc tttcctctta
    19261 aagtatgcct tctaatagtc ccttcataaa gtcctcagag tgaaattcac cgatatcatc
    19321 aatagcctca ccaaagccaa tcagcttcac tgggatatcc aattcctgac gaatagctag
    19381 gacaattccc cccttagctg taccgtcaat cttagttaaa atcaagcctg tgagcggtgt
    19441 gatttttgaa aactccttag cctgactcag agcattttgc cccgttgagg catcgagcgc
    19501 tagcagggtt tcgtgtgggg catcaggtat gacacgctta atgattcgtc ctattttttc
    19561 aagctctgcc attaggttgt ccttattttg caggcggcct gcggtatcaa tcaggagaat
    19621 atctgccctt tcagcaacag ccctctcaac gccatcaaag accacagagg ccggatctgc
    19681 tttttcaggg cctgtaatga ccggcacatc aacccgtcgt ccccattcaa ccagctgggc
    19741 aaccgcgcct gctcggaagg tatcagctgc aacaagcata accttttttc cctcttgctt
    19801 ataccgataa gctagctttc caattgatgt tgtcttacca acgccattca ccccaacaaa
    19861 gagcataacg gtcaagccag gctgataatg aatcgcttca ttgtagcggc catccccctc
    19921 ataaatagcc actagcttat caatgataag acgctttaga gcctctggct ttttagcatt
    19981 ttcaagctta gcctcatagc gcaattcttc agtcaaggtt gtggcaacat gaacaccaac
    20041 atctgagaga atcaaaagct cctctaagtc ctcaaagaag tcctcgtcaa cacgtctaaa
    20101 gttagcaaag aagctgttca agcgtgctga aaagcctgta cgggttttct ttaagctgcg
    20161 cttgtatttt tcctgatcag attcagctga tagggtctct tgcttttggc cttcctcagc
    20221 tggctgatca gctgaaccag caggtgcttg agctgctact tgatactcag catttgtctc
    20281 tgcctgatct tctgttgatg cgtctgcgct ctcgttacta tgctctgact tagccctatc
    20341 atgcttagcc tcctccatag cctcgtgctg gcttaggctc tcacctgcct gatccaaggt
    20401 cttgtcatca gtagctgcta actctagctc cggctctctt tctaaaagaa aagctcctct
    20461 agctgctgga tcaagccctt cagcttgctc tgaagcagcc tcgtctgaga gctcagcctg
    20521 tttgctagtg tcatcggtcc tagagaccac atcagctgcc actgcatgag catttgtatc
    20581 tgataaggcc tccttttcag actcaatcgt atcctttgac gttatgtcct ccgacaatac
    20641 ctctgtagtg gcagcctctt gctcagcaac cttagtctta tccttttttc caaataagcg
    20701 ttcaaataat cccattagcc ttcctcattt aaaatatatt tccaaatagc ctcagccaca
    20761 cctgattggt cattggttag ggtagtcact gcatctgcca cttccttagc ctgatcaacc
    20821 gcattggcca tagccacacc aagacctgcc cattgtagca tgctaaagtc attggcctca
    20881 tctcccatcg ccatgacatg cttggcctcc aagcccaagt gctgacaaag caggtccaaa
    20941 ccaaatgcct tatgaatccc cttaggcata atctcaaaga tgatgtctcg tgatttaaag
    21001 gcctcaaaat cctcaaagat agtctttgga agccttgcaa gctgctgatc caagaccttt
    21061 ggatccgtca ccgtaacaat tttattgtat gtgatgtcct ttggcagctc agcaaatgat
    21121 ttaaggctaa caaagttcag caagggactt gccaagtgat actgagagcg tctgccatca
    21181 ttgcctgata gactataaac agtaccatca ctgataacat cagtaggtaa gccaaccgct
    21241 gccaactgct gatgaatgtc ataaacctca gcaaggctta gagcgctttt atctaaaata
    21301 tgaccagtat ttcgttgaac cagaccgcca ttaaaggtaa tgctatagtt ctcttcacct
    21361 agcaaatcca gctcctcaag caaatttccg atagccttaa gaggacgtcc ggttgtgata
    21421 acaaccttaa ctcctttttc cttagctgct gctagagctt ttttgttctc atcactaacg
    21481 attttttcgg tattatagag agtcccatct aaatctagag ctaaaagctt tatacgcgtc
    21541 atttacacca atccctccaa ataagttaac actgctgagt cattacaatg accaataacc
    21601 tgatcagaaa tcgctttgat ttcaggcctt gcattttcag tagcaatagc ctgccctgca
    21661 aaggacagca tttgataatc atttagatta tcgccaaagg caatggtctt ttccggtaaa
    21721 atgcctaggt gctgacacag ctgatccatg ccaaagccct tatgaacctc ttttaggata
    21781 atatcaatcg aatcaaagcc agtcgtcacc gcagaagcat aggacagctc ctgatttagc
    21841 cagtcactgc cagctaagac tgtttctcct gtaaaggtcg ttgaggcttt aaaaacagtg
    21901 tcatcaacaa tatcctgcag acaatcaata agctgaacat tttcataata ataatgcatt
    21961 ttttggatat aatcctccgt agctcctttg agcacatagg ctgccttttg ccctgaaaag
    22021 aggatcccag actgattgta ataaggattg gcaagaattt tctctacaat gtcatgacac
    22081 tgctgcttgg tcatgacatc agcaaaaaga atgtccctct tgtattgcac cacagaccca
    22141 ttctcagcga taatggcaat gtcatctaaa aaaggctcaa acaagtgatc aatggctaaa
    22201 agcgaacgcc cactagaaac tgtaaagaga atcccttttt ctcttagctt aggcaacaga
    22261 gctgccaagc gctccttgtc ataagttccg tcctctctta aaaaggttcc gtccatatct
    22321 gttgctatca atttaaccat acaatttaac catttccttt ttagggagat actgattcag
    22381 ctattcagct ctcccaaaaa tctctttttc cattatacca tatctaaaca aaaagggcgt
    22441 gcctgtccta acacgtcctt gttttaaggc tttataattt ctgtagtggg taactccact
    22501 gtggagatta ttgagccctt attccaaggc tttctttatg ttctattgta tcaatttcct
    22561 tattccaatt tctgttgcaa ttaactttaa catacaatct aaccatttca ctttcaaggg
    22621 agtgcaaaac ccgagtgggg tgtgcaactc aaatcccagt ataactcctt tcgttatacc
    22681 acaggtagac caaaaaaggg cgtgccatct gacataccct tgttttaaca gtcaatctga
    22741 gctccgtttt taaaggctaa acttctttat ctccatactc tcaacgctta tttgccataa
    22801 ttcttaattg aagcccgtca ctaagttttc ttgttactaa agagttgagt aatgaatcta
    22861 tctagactga tgatttttct ccttaaaagc ttcatatagt tttttatata acgctttctt
    22921 ttcttttttc tgagcattaa actctttttt accgtaatca aaatttgcta ccacaaaccc
    22981 cttgttattg ttagaaaaat caaaaaattc catttcgatt aatttgttat tcttagaatc
    23041 ttctatagta ttctctaaat gattgttgaa ttgtttaaca tcttcttcac taactccaaa
    23101 acccatagca gctccgtctg caatgatgtt tgaaaatatt tcttctgaag atgctgcttc
    23161 ttttaccctt attaggtata tggcttcttc tgtttctaat tgtcttactt tattccattt
    23221 ttgggtatca ctagaagaga tcgtatagac tgttaaatct accgtaggtt tattgggatt
    23281 ttcttttttt attacttgtt ttcccactaa gaaaattgcg agtattccaa ttaataatat
    23341 caacgtcata taagctttct ttttcatatc tcactcccta tatctttcaa atcaatgata
    23401 acatcaacct tattatatac agctggatca tgtgttgcta taataacata tttattttcg
    23461 gctgtttcac tcaataataa attaatgatt tcttttccaa tctcactatc caaagctcct
    23521 gtaggttcat ccgctaaaat aattttacgt ggcttcatta acattcttgc aatagctaca
    23581 cgctgaacct
//
LOCUS       DARYVE010000026        23204 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYVE010000026 DARYVE010000000
VERSION     DARYVE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23204
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..351
                     /locus_tag="TVW25_001010"
     CDS             <1..351
                     /locus_tag="TVW25_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378651.1"
                     /translation="RGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKK
                     EPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGF
                     IASAGLLVFKRKKN"
     gene            877..1767
                     /gene="rapZ"
                     /locus_tag="TVW25_001011"
     CDS             877..1767
                     /gene="rapZ"
                     /locus_tag="TVW25_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1378652.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            1764..2741
                     /locus_tag="TVW25_001012"
     CDS             1764..2741
                     /locus_tag="TVW25_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1378653.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            2738..3649
                     /gene="whiA"
                     /locus_tag="TVW25_001013"
     CDS             2738..3649
                     /gene="whiA"
                     /locus_tag="TVW25_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1378654.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            4009..5406
                     /locus_tag="TVW25_001014"
     CDS             4009..5406
                     /locus_tag="TVW25_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1378655.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            5646..7196
                     /locus_tag="TVW25_001015"
     CDS             5646..7196
                     /locus_tag="TVW25_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1378656.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
     gene            7467..8195
                     /locus_tag="TVW25_001016"
     CDS             7467..8195
                     /locus_tag="TVW25_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1378657.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            8207..9382
                     /locus_tag="TVW25_001017"
     CDS             8207..9382
                     /locus_tag="TVW25_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1378658.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            9392..10387
                     /gene="lacD"
                     /locus_tag="TVW25_001018"
     CDS             9392..10387
                     /gene="lacD"
                     /locus_tag="TVW25_001018"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1378659.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(10429..11148)
                     /locus_tag="TVW25_001019"
     CDS             complement(10429..11148)
                     /locus_tag="TVW25_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1378660.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            11288..13051
                     /locus_tag="TVW25_001020"
     CDS             11288..13051
                     /locus_tag="TVW25_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1378661.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQERLKECYPQLS
                     FAEPMISSTMALESIKLSARVSLFKTIKNVSAIKKSFYPCNMEELDQPTGYLLYRTHL
                     ARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEGETTQLDILVENMG
                     RVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHFPLDFQELDWIDFSAGWTDEVPGFY
                     AYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQGQNRLL
                     IFETEGQFSESIRLTKEPIYK"
     gene            13069..13554
                     /locus_tag="TVW25_001021"
     CDS             13069..13554
                     /locus_tag="TVW25_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1378662.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            13600..14481
                     /locus_tag="TVW25_001022"
     CDS             13600..14481
                     /locus_tag="TVW25_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1378663.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            14468..15286
                     /locus_tag="TVW25_001023"
     CDS             14468..15286
                     /locus_tag="TVW25_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1378664.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            15290..15694
                     /locus_tag="TVW25_001024"
     CDS             15290..15694
                     /locus_tag="TVW25_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1378665.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(15798..16058)
                     /locus_tag="TVW25_001025"
     CDS             complement(15798..16058)
                     /locus_tag="TVW25_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1378666.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(16183..17115)
                     /locus_tag="TVW25_001026"
     CDS             complement(16183..17115)
                     /locus_tag="TVW25_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1378667.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(17125..17553)
                     /locus_tag="TVW25_001027"
     CDS             complement(17125..17553)
                     /locus_tag="TVW25_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378668.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            17811..18836
                     /locus_tag="TVW25_001028"
     CDS             17811..18836
                     /locus_tag="TVW25_001028"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1378669.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            18897..19343
                     /locus_tag="TVW25_001029"
     CDS             18897..19343
                     /locus_tag="TVW25_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1378670.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            19672..19965
                     /locus_tag="TVW25_001030"
     CDS             19672..19965
                     /locus_tag="TVW25_001030"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1378671.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            19946..21177
                     /locus_tag="TVW25_001031"
                     /pseudo
     CDS             19946..21177
                     /locus_tag="TVW25_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            21323..21670
                     /gene="rplS"
                     /locus_tag="TVW25_001032"
     CDS             21323..21670
                     /gene="rplS"
                     /locus_tag="TVW25_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1378672.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            22185..22256
                     /locus_tag="TVW25_001033"
     tRNA            22185..22256
                     /locus_tag="TVW25_001033"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22218..22220,aa:Arg,seq:cct)
     gene            complement(22380..23183)
                     /locus_tag="TVW25_001034"
     CDS             complement(22380..23183)
                     /locus_tag="TVW25_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1378673.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
BASE COUNT         6572 a         4462 c         5393 g         6777 t
ORIGIN      
        1 cgtggcgagc aaggaccaaa aggtgatcgt ggcgaacaag gaccaaaggg tgatcgtggc
       61 gagcaaggac caaaaggtga acgcggtgag caaggaccaa aaggcgatcg tggcgagcaa
      121 ggtccaaaga aggagccaga aaaagacacc aagccatcag tgccaaaggc accagataat
      181 atggctgcac caaaggctcc ggagaagaag aaccctaaag caccggctcc taagtcagct
      241 ccaaaggcat cattgccatc aacaggagac actagccaat catttgttgc agcagccctt
      301 ggctttatcg ctagcgcggg cttgctagtc ttcaaaagaa agaaaaacta agctagctaa
      361 agactgtaaa caagcctcaa ctgttacagc aagcctcttt gacatcttgc agataagagg
      421 atttcttagc gaatgaagtg tgtctaaagt cagatactct gctggactag cagtagctga
      481 tctccctgaa aatcagttat gctaaagcat tgagccttag ttgcaaggct taggtgtgac
      541 cttccaaagg aagctgcttt tgcctgtatc actttaggaa gatatctaaa agagacactt
      601 ttttcacgct gaagctaagc tagcttttcc tatgacaaat atcctataac aataaactcc
      661 aaacaaaaga gaggtcaaat ggtacctctc ttttacttag ctttaggatt gatagattct
      721 aaaggcttcc ttgtttcttg atcaagaagt ccttactgat agagtctgtc ttagccgggc
      781 ttatatggta taatacctaa tggagataag aaaagtcctt aacaaataga gtttcatcta
      841 ttgttacagg agcaaccaag tgaaaggaga tgctacatgt cagataaaca aatcaatttg
      901 gttattgtta caggaatgag tggcgccggc aaaacagttg ccattcaatc atttgaggat
      961 ttggggtatt ttactgttga taacatgcca ccagctttag tgcctaaatt tttagagctg
     1021 cttgagagga ccaatgaaac ccaaaaggtt gctctggtag tggatatgcg cagcagacgc
     1081 tttttcaagg agattaactc tatcttagat catattgagc taaatgccaa cctcaagcta
     1141 cggatcctct ttcttgatgc gactgatagt gagctagtgt cacgctataa ggaaactaga
     1201 agaagtcacc ctctggctgc tgatggtcgg gtgcttgatg ggattcgacg agaaagagag
     1261 ctgttagtcc cgcttaagag catgagtcag catgtggtca ataccaccga tctaacccca
     1321 agacagctgc gtaaggtgat ttcggatcag ttttcaagcg agtcagacca agcctcattt
     1381 agaattgagg tgatgagctt tggctttaaa tatggcctcc ccttagatgc ggaccttgtc
     1441 tttgatgtgc gctttttgcc taatccttat tatcaggtgg cgctaagaga gcagacaggg
     1501 cttgatcagg ctgtttttga ttatgtgatg actcatcaag agtcagaggc cttttataat
     1561 catttgttag gcttgattgt tcctattttg cctgcttatc aaaaggaagg caaatcagtg
     1621 ctaaccattg ctattggctg tacaggtggt cagcatagaa gtgtcgcctt tgcccatcgc
     1681 ttggcccaag acttgacagc agactggccg ctgcatgaga gtcatcggga catcaatcgt
     1741 cgtaaggaaa cggtaaatcg ctcatgagaa atcctaaaat aacggtgata ggaggaggaa
     1801 caggtattcc tgttatccta aaaagccttc gcaaggaggc ggttgacatt actgcggtgg
     1861 tcactgttgc tgatgatggt gggtcatctg gtaagctgcg caatgccatg cagcttaccc
     1921 cgccaggtga tttgcgcaac gtcttgttgg ccatgagtga catgcctaag ttttatgagc
     1981 gtgtgtttca gtatcgtttt aatgaggcag atggtgctct agctggtcat cctctaggca
     2041 atttaattat cgcaggtatt tctgagatgc agggatccac ctataacgct attcagattt
     2101 tgacgaaatt tttccatatc accggcaaga tttttccctc aagcgagcag cccttgacac
     2161 tgcatgctgt ctttaaggac ggtcatgagg tgtcaggaga aagctctatt gccagctacc
     2221 aaggcatgat tgaccatgtc tatgtgacca atacctacaa tgatgacctg ccaaaggcca
     2281 gtcgtaaggt ggttgaggcc attctccaaa gtgatatgat tgtgcttggt cctggttcct
     2341 tgtttacctc tattttgccc aatcttgtaa ttccagagat caaagaagcc ctgagagtaa
     2401 ccaaggcaga ggtggtttat atttgtaaca ttatgaccca gtacggtgag acagagcaat
     2461 tttccgatgc ggatcatgtt gcggttttaa atcagcatct gggcagggac ttaattgaca
     2521 ctgttttggt taatgttgag caggtgccaa aaagctatat gaattccaac caatttgacg
     2581 aatatctggt ccaagtagag catgactttg caggtctgtg taagaccgca aagcgtatca
     2641 tctcgtctaa ttttctgcgt ttggagaatg gcggagcctt tcatgacggg cacttggttg
     2701 tagaagaatt aatgaaccta gttaggataa ccaagctatg agttttacga caactgttaa
     2761 agaagaattg attcatttat ctgcttctga tcaaacagaa ttatcagcaa tcatcaagct
     2821 ggctggtagc ctaggcttgg ctaatcagag cttgaatttg tctatcacaa ctgaaaacgc
     2881 taagattgct cgctacatct atgcgcttat cgaagacacc tatcatatca ttccagaaat
     2941 caggtaccat caaaagacca acttgaaaaa aaatcgtgtc tatacggttt atttggataa
     3001 gcaggtggat aagctcttag cagatttaaa gctggcagat tctttttttg gcattgagac
     3061 aggtattgag cagcaggtca tgtcagatga tgatgctggt cgggcctatc tcaagggtgc
     3121 ttttttagcg gcagggactg taagggatcc agaatccggc aagtatcagc tagagatcta
     3181 ctctgtctat ctagaccatg ctcaggattt ggcccagctc atgcacaaat tcatgctaga
     3241 tgccaaggtt atcgagagaa aaaatggtgc agtaacctat ttgcaaaagg ctgaggacat
     3301 catggatttt ctcattatta ttggtgccat gtcgtgtaag gaggagtttg aggctgttaa
     3361 gcttttgcgt gaggcgagaa atgacatcaa tcgggccaat aatgcagaga ctgctaatat
     3421 tgctaaaacc atcaccgcca gcatgagaac cattaataat attatcaaaa tcatggatac
     3481 gattggctta gacagcctgc cagttgagct gcagcagatt gcccagatga gagtagccaa
     3541 cccagactat tctcttcaac aaatcgcaga ttcgcttgac tttgccatca ctaagagtgg
     3601 ggtcaaccat cgcctgcgaa aaatcaataa gctggcagag gatttataaa gacagcttag
     3661 cctttttcag gctgataaaa aagggggtaa ggtgatacga acaagccgcc ttttaaggca
     3721 tgccttgttg agctttctct aggctgttga tggagtgatc tcaaggcgct tttgttactg
     3781 tcattccaac aggctatctg attttgggat gacttcttac taataagctt ttctaatggc
     3841 tggctgacaa cgattagcga tatagttaag gcttatcgtg attcaacaag aggctttagt
     3901 ctcttttttg cttgtcagaa ttattttttt aggcttttct tacaaatgag aggacaatgt
     3961 gacaatctgt ggtatgatat tagtaatgaa tacaaaggag aacaaatcat gtcatgcaca
     4021 actattcttg tcggtaaaaa agcgacctat gatggatcaa caatcgttgc tcgtacagag
     4081 gattcacaaa atggggaatt tacccctaaa aaaatgacag ttgttagacc aaaagaccaa
     4141 cctagacact atcaatctgt cttgtctagc tttagcatgg agctgccgga tcagccgatg
     4201 gcttatacct cggtgcctga tgccctagga aaggacggta tctggggaga agcaggtgtc
     4261 aataccctca atgttgctat gtcagcaact gagaccatta cttcaaatgc tcgcgttctt
     4321 ggagcagatc ctcttgtttc ctctggtatt ggagaagagg acatgctgac cttggtgctt
     4381 ccttatattc ggtctgcaag agagggtgtt cttcgtttgg gagctatcct agaagcatac
     4441 ggtacctatg aggctaacgg tgttgccttt tctgatgagc atgagatttg gtggctggaa
     4501 acaataggtg gtcatcattg gattgcaagg cgcgttcctg atgatgctta tgtcactaat
     4561 cccaaccagt ttggccttga tcactttgaa tttaacaatc cagaggaata cctgtgttcc
     4621 aaggatttaa aggactttat tgccaaatat catctagatt tgacctatag caacgagcat
     4681 tttaaccctc gctacgcctt tggtagccaa agagataagg atcgccatta caatacacca
     4741 cgcgcttgga ttatgcagca atactttaat ccggagtttc tgcaggatcc gcgcagcttt
     4801 gaacttcctt ggtgccaaag acctgatcgc aaggtgacca ttgaagacgt taagtacgtg
     4861 cttagcaatc attatcagga caccccttat gatccttacg gcccagaggg aacgccgact
     4921 agtcgaaaat cctttaggcc gattggtatt aaccgtacga gtcaaactgc tattttacat
     4981 atccgtccca acaagcctaa ggaaattgct gccattcagt ggatggccta tggttcgatg
     5041 ccctttaata caatcgttcc gctattcacc caggtcaaga ccattccaga ttattttgca
     5101 aacactgttg aaaatgtttc cacagacaat ttctattgga ccaatcgctt gattgcagcc
     5161 ctggctgatc ctcacttcaa gcaccatgaa gcagatttgg aggactatct cgaaaaaaca
     5221 atggccaagg gtcatgccat gctgcatgct gttgaagcag cgctagtaaa aggtcagccg
     5281 gttgacctag aagaggccaa ccaaggcatg agtgatgaca ttcaggcaga tacacaggct
     5341 ctgctcaata agatcctctt tgatgctagc aatctcatga ccaaccgctt tagcctaagc
     5401 gactaagtaa tctcaatagt caaacgagct catatcatta tagatatggg ctcttagctt
     5461 gaaaaggata gtagagcggt cttatagtca gactaattaa tggtaacgat gagtccagtt
     5521 aaggtaaaaa aagagcactt agctaatgca aaaaaagtaa aaaacttgca aaagaatgat
     5581 attgtgttat acttaaccag taaatattaa gagctatttg cgatatgata tatagaggag
     5641 gaatcatgaa aaagaagtat cttttaatga tgagtgtgct cggtgtcttt tttgcgggac
     5701 agatcagtca agcaaaacag gtcctagcag atagtaaggt caaaattgtt accaccttct
     5761 atcctgttta tgaatttacc aaaggcgttg tcggaggtga gggaaatgtg tctatgctga
     5821 tgaaagcagg aacagagcct catgattttg agccgtcaac aaaggacatc aaaaagatcc
     5881 aagatgccga tgcctttgtt tatatggacg ataatatgga aacttgggtc cctgatatga
     5941 agaaatcact gacttctaag aaggttacgg tgattaaggg aacaggagat atgctattgg
     6001 tagctggctc tggtcacagc cacgagcatg accatgacga tgccgataaa aagcatgatc
     6061 atgaccacga cgaggaagga cacagccatg cttttgaccc gcacgtatgg ttgtcacctt
     6121 atcgcagcat caccgttgtc gaaacaattc gtgatggtct atctaaggcc tatcctgaca
     6181 aggctgacca cttcaaatct aatgccgctg cttatattga aaagctcaag gaattagata
     6241 aggagtatag tgacgctttt tcagctgcca agcaaaagag ctttgtgact cagcacgcag
     6301 cctttggtta tatggcgctt gattatggct tgaaccaaat ctcaatcaat ggtgtcacac
     6361 cagatacgga gccttcagct aagcgcattg cagagctatc aaaatacgtc aaaaaatatg
     6421 acattaacta catttatttt gaagaaaatg cttcaagcaa ggttgccaaa accctagcca
     6481 aggaggctgg tgtcaaatca gctgtcctta gtccgcttga aggcctaact gaaaaggaca
     6541 tgaaggccgg caaggattac tttaccgtta tgcgtgaaaa cctcaaaacc ctacgcttaa
     6601 caactgatgt agaaggaaaa gaaattcttc cagaagagga taccactaaa actgtttata
     6661 atggctactt taaggataag caggtcaaag accgcaaatt gtctgattgg tctggtaact
     6721 ggcagtctgt ttacccattc cttcaagacg gtacattaga tcaggtatgg gactataagg
     6781 ctaaaaaatc taaaggaaaa atgaccgcag ctgaatacaa ggattattac accactggct
     6841 atcagacaga tgtcagtcat atcaagatta atggtaagaa aaataccatg acctttgttc
     6901 gtaatggtga aaataaaacc tttacttata agtacgtcgg taaaaagatt ttgacctatc
     6961 caaagggcaa tcgtggcgtg cgcttcatgt ttgaagctaa ggagccagac gctggtgaat
     7021 ttaaatatgt tcagttcagt gaccatgcta tcgcgccagg taaggcggag catttccacc
     7081 tatactgggg tggtgacagc caagaaaagc ttcacaaaga gctagagcat tggccaactt
     7141 actatgatgc ggacctatca ggtcgtgccg ttgcccaaga aatcaatgct cattaaccac
     7201 tcaaaagact aggcagttca atcggcctag ttttttcttg tcttagttgc tgtataggac
     7261 ctaaatgctg atagctggtc ttaagattta tttttaattt ttctaactat atttaggttg
     7321 tatttgtttg ttaataccaa atccattgtt ttagggatta tatagaatta atatgttaaa
     7381 tattttaata tttttcaaaa aagtattgac ttttagattg taatataata ttatttaagt
     7441 ggttataata agttagaggt gttagtatga taaaggaaca gccactctac ttacaaattg
     7501 ttgatgtatt agaggtcaaa attagaaata ccatgtcagc taatgataaa ttgttatcag
     7561 aacgagagct aagtgactta tttggtgtta gtcggataac cattagattg gcacttaagg
     7621 agctagagct gcgtgggctt atttacaaac agcagggcaa ggggacctat gtatcaggca
     7681 taaaggagcc tgctacagac ctgtcctcag cctatagctt taccgaagag atgaaaaagc
     7741 aaggtcgtaa gcctcaaaca gtcattcttt catttgaaaa aatcaagacc acagcttact
     7801 tgtctggtat gttagattta gatgttgata ctgatgtttt tgagctagag cgtctaagga
     7861 ttgcagatgg aaagccatta atgtttgagc gcacttatat acctgaaagg ggatttgagg
     7921 cgataacgat tgatttattg gaaaaaaagc ccttatatga tgtgtttgct gaggattttc
     7981 aggaagctat ccgattggct gatgaggagt tttacgctag tatcgctcta gattatgaag
     8041 caaagctatt agggatcaaa aagggggatc ctgtgctgca tattatgcgt aagacctata
     8101 atgagaaaaa taggctaatc gaatttacct ttagtattgc tagagcagac cagtttaggt
     8161 accgtatcca gcaccaccct aacaagaaga tataggaggt aaggaaatgt ttacaaaaac
     8221 acaagcagaa ctagagctac ttggcgcagc tatcaccact agagaaatca agcagcagcc
     8281 agagctatgg tcagaggtct ttgagtcttt tctgaagcaa aaaaaagacc tcttagcctt
     8341 ttttgacagg attattgaaa gcgctaacag aaacaaggta aaaattattt ttacaggagc
     8401 tggaacttct gaatacattg gcaataccat ttgtcattat ttggagatga ctggtgacag
     8461 ggaaaattat ttatattaca gcattgcttc cacagacctt gttgcagctc caagccagta
     8521 tctctttgaa gaggatacag tcgtgcttgt ttcctttgca agaagtggca atagtcctga
     8581 aagtgtcgct gctgttagtc ttgttaatca gctggtgtca aatccttatc atttggtgat
     8641 aacctgtgcc aaagaggggg ccttagctca aaatgctaag aaggacaaaa ggagctattt
     8701 attcttgctg cctgaggcct caaatgacgc tggctttgct atgacgggaa gctttagctg
     8761 catgatgcta gcggccttgt tgatttttga tcaagcgcat tcccttgagg agaaaaaatg
     8821 ctatttagat cagattgtag gtatggtggc agctattatt cagcaggagg ctgatttaca
     8881 aaagctggtt agcttagagt ttcaacgctt ggtttacctg ggatcaggag ccttagcggg
     8941 gcttacgcaa gaggctcaat tgaagatttt agaattaaca gctggcaaaa ttgcaacagt
     9001 ctatgactcc tcaatgggct ttaggcatgg tccaaagtca tttattgatg atcagacatt
     9061 ggttattggt tttgttagca atgatcctta tacgagaagg tatgaccttg atgttttaga
     9121 agagataaga gaggatgcta ttgctgttga tacggttgca ttacagcagc aaggaggtga
     9181 gggctttagt gggcattgct ttggcttaga ctcgtcaatg ctattgccag atgcttattt
     9241 ggcctttccg cttgttttta tcgcccaaac gcttgctttg ctgtcgtcta ttaaggttaa
     9301 taatttacca gatactcctt cggccacagg aacggttaac agggttgtcc aaggtgttaa
     9361 gatttatcac tattttaagt aggagaacaa gatgtaccat ttatcaaaag ctaagtatcg
     9421 tcttcttgaa aaggtcagtc gtaagggcat catttcggcc ttggcctttg atcaacgcgg
     9481 ggttttaaag cgcatgatgg cagcccacca agacacagag ccaactcctt ggcaaatcga
     9541 agccctaaag gctctggtat cagaggagct aaccccctat gcctcctcta tcctgctaga
     9601 ccctgaatat ggcctgccag ccaccaaggt gcgtgatgag aagtctggct tattattagc
     9661 ctatgaacaa accggctatg acacaaccac cactagccgc ctgccagatt gtctggtgga
     9721 ctggtcagtc aagcgcctca aggaggccgg agctgacgca gtgaagttct tgctgtacta
     9781 tgatgttgat ggtgatgagc gtattaacca acaaaagcag gcctatatcg agcgtatcgg
     9841 ctcagaatgt caggcagagg agataccatt tttccttgag ctattgacct atgatgaggc
     9901 gataacagac aatcagagtg tagcttttgc caagctaaag gcacacaagg ttaatgaggc
     9961 catgaaggtc ttttcaactg agcgctttgg ggttgatgtc ctaaaggtag aggttcctgt
    10021 caatatggcc tatgttgagg gctttgcaga gggtgaggtt gtttacagca aagaggaggc
    10081 tatgcaggcc tttcgtgacc aagaggcagc tagtcacttg ccctatattt atttgagtgc
    10141 gggtgtatca gctagtctgt ttcaagagac cttggttttt gcggcagagg caggagctag
    10201 gttcaatggt gtgctgtgtg gtagggccac ttggtcagga gcagtagcgg tgtacatgtc
    10261 agagggcgag gaggcagcgc gtcaatggct tcgcacagag ggttttgaaa atattgatcg
    10321 tctcaatcag gtgcttgaga aaacagccag cccttggaca acaaagctta ctcttgatga
    10381 agcctagtaa aggcatgata aaagcaatac taggacattg cttctgtatt attggtaatc
    10441 actggaggac aaggcgtact tgaaaaattg ccaatgcttg taggactcgg tgtactctag
    10501 aatacggcca ttatctgtcg accgagtgag cttggtttga aggacacaag gagtgttgtc
    10561 tatcatgttt aaaaatgtag cgacatcttt aggcatgtga tccgtcagct gtgtttgctg
    10621 ggtgaagctt tgtgatcgca tttgaatgtg aaaatccaaa aagaagcgct tataaagcga
    10681 ctggtaatca gctaaatcac gctcagggca cagcaggtaa tcatgaggaa tataagatag
    10741 ctggtataaa tagggctgct gattaatcgt tcgtgtacgg gagatggtgt agtaaaattc
    10801 cgttttatga agtttcaaga gatttagata gtagggatca tttcccttaa ctacactaag
    10861 gacagtcacc tcctcttttt gatccttaaa ggtacctaga taggaaaatt ggactagctg
    10921 ttcttttctg gtacgggtaa tgaaggttcc aagtccctgc cttcttctga taaagccttc
    10981 tttttctagt tctttaaggg ctcgaatgat ggttatggag ctaacatgaa agcgtttaat
    11041 cagctcggct tcggtataaa atttgtcccc ggtatggtag tggccattca gaatttggtt
    11101 ttgcaattct tctttgatta gtcggtactt tgggtatttg atggtcatag ttactcactc
    11161 aataattgtt tagtacgatt atagcaaaaa tagtaagctg atgtcatatc ttaccagtta
    11221 ttgctcagat agcttgtcaa tcagtcattg atcaaaggct gatggttaat gaataaaagg
    11281 agataatatg aagcaatttt gcataaagga gcagttttac cttgatggca agccgtttaa
    11341 gatattatca ggtgccattc attactttag aatagctcct gatagctggt ctagggtgct
    11401 ttatcagctg aaggccttag gctttaatac agtagaaacc tatattcctt ggaatatgca
    11461 tgagccaagg aagggacagt ttacctttga ggggattgca gatgttgagg catttttgga
    11521 tttggcacag gaatgtggcc tatatgctat tgtcagaccc tctccttata tctgtgctga
    11581 atgggagttt ggtggtttac cggcttggct attaactgaa aattgtaggc tcagatcaag
    11641 cgatgaggtc tttcttaagc atgtatcaga ttattatgat gtgttactac caaagctggt
    11701 gaagcgtcag ttagataatg gcggcaatat tctgatgttt cagcttgaaa atgagtatgg
    11761 ttcttatggt gaagaaaagg cttatttaag aaaattaaaa gagcttatgc ttgctaaagg
    11821 cattagtgcc cctctcttta cctcagatgg gccttggcca gccacgctag catcagggag
    11881 tctgattgac gatgatgttt ttgtgacagg caactttggg tcaaacgctt caaagcaatt
    11941 tgccagtatg caggattttt tccaagcaca tcaaaagcaa tggcctctga tgtgtatgga
    12001 attctggttg ggctggttta atcgctggaa tgagccaatc attcgaaggg actccaagga
    12061 agctgttgat gcaatcatgg aagctataga gctaggcagc attaaccttt atatgttttg
    12121 tggtggcact aattttggct ttatgaatgg ctcgtcagct cgtctgcaaa aggatttacc
    12181 acagataacc tcctatgatt acgacgcatt actagatgag gcagggaacc cgacaaagaa
    12241 atataccctg ctgcaagaac gtctcaagga gtgttaccct caattatcct ttgcagagcc
    12301 aatgatcagt tctacgatgg ccttagagtc tatcaagttg tcggcaaggg ttagtctttt
    12361 taagacaatc aaaaatgtaa gcgctatcaa gaaaagtttt tatccttgta atatggagga
    12421 gctagatcaa ccaacgggct acctactgta tagaacgcac ctcgctagac atagcaagga
    12481 ggagcggctc agggtcattg atgctagaga ccgcattcag ctctttttag atgaaaagca
    12541 cgtgaaaacc cagtatcagg aggaaatcgg tcaggatata ctgatacatc aagagggtga
    12601 gaccacacag cttgatattt tagtcgaaaa tatgggacgt gtcagctatg ggtacaagct
    12661 gacagcacca agccaacaaa aaggattagg cagaggctta atggctgact tgcattttgt
    12721 aggtgattgg gagcattttc cactagattt tcaagagctg gattggattg atttttctgc
    12781 aggttggacc gatgaggtgc caggatttta cgcctatgat tttgattgtc agcagccggc
    12841 agatacctac cttgatttga gtcaattcgg aaaaggaatt gcccttgtaa atggtgttaa
    12901 cctaggacgt ttttggaagg tcggtccaac attatcgctt tatattccta agggactatt
    12961 aaaacaaggt caaaatagac tgctgatatt tgaaacagaa gggcagttta gtgagtcaat
    13021 tcgtttaact aaggaaccaa tttataaata gataaaagga gaaaacttat gacaattgtt
    13081 gcagcacgta ttgacggccg gttaattcat ggtcaggtag ctaatctatg gacgacaaag
    13141 ctaaacatta gccgtatcat ggtggtcgat aatgaggtga ttagcaatga ccttgaaaaa
    13201 acagcactga agctagccac acctagcggt gttaaattat ctatcttatc tgttgaaaaa
    13261 gcagccaaca atattttgga agggcgctat gattctcaac gcttgttgat agtagccaga
    13321 aagccggata gctttttgga gctgattcaa aaaggggttg ctatttcaga gttaaatgtc
    13381 ggcaatatgt cacagacacc ggagactcgt ccagtaacgc gttctattaa cgttgtagac
    13441 gaggatatag aggcattcaa ggctatttca gccaaagggt gtcatctcat tgcccaaatg
    13501 gtgcctaatg atgccccagc agactttatg ccgctgttgg ataaggttga ttaagatgtg
    13561 tcaaatcaaa aacgaatctg tttcaggagg taaaagctta tgattcaatg gtggcaaatc
    13621 ctattattaa cactctactc agcttatcaa atattagatg agctaacaat tgtctcttct
    13681 gcaggctcac ctgtatttgc aggatttatt tcaggtatca tcatgggaga tgtgcaaacc
    13741 ggtctttgga ttggtggtag ccttcaattg atggtgcttg gtgttgggac ctttggagga
    13801 gcttcgcgta tcgatgcaac ctctggtgcg gttattgcga cagccttctc ggttgctcaa
    13861 ggcatagagc cagaattagc gatttcaacc attgcagttc cggtagcggc cttgctggtt
    13921 tatactgata ttctaggacg cttttcaacg accttctttg ctcaccgtat tgaccgccat
    13981 gttgaaaact ttaactaccg aggcatcgag cgtgattacc ttatgggagc tgtaccttgg
    14041 gccctatcac gtgctctgcc ggtattttta gcggtctctt taggtggtgg tgcggttgat
    14101 acagttgtta agttcattga ccattatgaa tggctagcaa atggtctaac tcttgcagga
    14161 aaaatgcttc caggcttggg ctttgcgatc ttgcttcact acctaccagt taaacgtaat
    14221 ctccattatc tggctttagg ttttggcttg acagcaatgc taacaaccat ttacaccaac
    14281 cttcaggtag ctggaggcgc ccttgcagga gtagccaagg atttcaatgc cgcaccattc
    14341 aaggggctgc caatgattgg tattgctatt attgggcttt ccttggcaac cctccattat
    14401 aaaaatggtc aacaagcacc tgtagctgaa caaaaacctg gggtatcaga aagtggggaa
    14461 attgaagatg acgaaatcta attataaatt aaccaaacag gattttaatc aaatcaataa
    14521 gcgcagcctg ttcacattcc aatggggctg gaactacgag cgtatgcagg gctctagcta
    14581 tctttacatg attttaccac agcttcgtaa gatttatggc gatggaactc cagagctaaa
    14641 agaaatgatg aagacgcaca cgcagttttt taacacatca aatttctttc atacgattat
    14701 cacaggaatt gacttggcgt tggaggaaaa tgaaggactt gcctcaaaag atgctgttaa
    14761 tgggattaaa acaggcttaa tggggccatt tgctccaatt ggtgattcgg tctttggctc
    14821 cttagtacca gctattatgg gctctatagc cgcaggtctt gctaaagaag gggtttggtc
    14881 agggattact ggtgtattga tgtgggtatg tactcagatg atcatcaatg tgtttcgttg
    14941 gaagcagctt gaaattgctt ataaagaagg tacaaagctc gtcaccacca tgcgtgataa
    15001 gctaactgct gtagtagatg cagcctcagt catgggagta ttcatggtag gggccttaat
    15061 tgcaacaatg attaattttc agtttaccgc agcacccaaa attggagaga aagttatcaa
    15121 tattcaagat ttaattgata ccatttttcc acgtctagtt ccagccttat ttaccggagg
    15181 tatcttctgg ctgctagggc gtaagggcat gtcaccaact aaggcaattg ttgtgattat
    15241 tttatttgcc ttagtgatgt cttatttcaa tattttagga gtatagctga tggcgcaaac
    15301 cttaattctc attagtcatg gagctttttg tcgagagcta aaacagagta cagaaatgat
    15361 tatggggcca caggacaata ttttaacagc agagctgcaa ccaaacgaag gtgccgatga
    15421 ctttaaagaa aagcttttaa ggctaattgc aggtttagat gacgtccttg tgtttgcaga
    15481 tttgatgggt ggaacaccct gtaacgttgc cagtcgtttg ttaatggaag gacatcagtt
    15541 tgagctgtac gcaggcatga atatgccaat ggtcattggt ttcattaatg cctgtttgat
    15601 cggtgaagcg tttgatttca aagcctttgc ctgtgacaat attcaccatg tcaataccat
    15661 tatttcagct ctagcagatg atgatgacga ctaaccaagc tcgcttattt gtcacgcacc
    15721 ttacggagcg aaacggacca agagccgcat aatcaaaaaa gacactgcca aatcttggca
    15781 gtgtctttgc tgtaagctta ttttgctgcg tttgcgtctt tgagaccgta tttcttgttg
    15841 aaacgatcca cacgtccatc ggcttgtgta aacttttgac gacctgtgta gaatgggtgt
    15901 gagtctgatg aaatttctac acgaacaaga gggtaagttt ccccttcaaa ctcaatggtt
    15961 tctttagagg tcttagttga accgctaagg aatttgtagc ctgtagttgt atcaaggaaa
    16021 acaactggac gataatctgg atgaatgtct tttctcatct taaaaaagtt cctttctgcc
    16081 atgatactgt ccgtatcata gttattaact actctagttt aacaaaagtt agtaagcttg
    16141 acaagctttt tctatcacta ttcatcaata agatgataag tcttatgtta agagatcaat
    16201 cagctcttgg tagatttgct cattttcctc taagcctgat gacgtggcac cgctagcaag
    16261 agggtgcccg cctccttgat gacgcttagc aataccattg atgacctttt ctttactgcg
    16321 catgcgtact cggtactggc catctggcag ctcaacaaag ataacccaag cctgcaccac
    16381 gtctattttt ccaggagcag agacaatcgc tgagctttct gccaagctaa taccaaagga
    16441 atttaggacc tcctggctaa gcagtaggcg ggctgcacca ctgtcatcta tatcaagctg
    16501 ctcaaaaaca tagccttgta gcttggcaat tttaagtgga aaggaatcca tctgcctcga
    16561 aatagcagca aagtcaaagg cataatttct taattggctt gcaatggcca gtgttttact
    16621 gcttgttgag gcatagagaa agcgtcctgt atctcccaca atgccagtat ataatagtct
    16681 agctgcctca tcagttaaag ccaagccttg gctaaaggca aattcagcaa taatctcact
    16741 agcacttgag gtcttggtgt caacgtagga gagatcacca tagacatcat cgttagggtg
    16801 atgatcaatt ttaatgaggc aagcgcccat tgtgtagcgc tcatcatcaa tgcgggggcg
    16861 attggcagtg tctgtaacaa tcactaaagc ttccttataa tcatcgtcgg acacctgatc
    16921 catgagacta atccaagcca gactaggctc atcaaagcct gttatcagga cctttttgtc
    16981 agggaaatta tgcctgataa tctctttaag tcctgcttgg ctccctagag catctggatc
    17041 ggggttttgg tgccgatgaa tgatgatggt ttgatagtgc ttaatgtgtt ctaaaatagt
    17101 ttgaaacgtt gtcataggta tcctttagtt tttgatcata tcaatgtgag gaatattgtc
    17161 ttccagataa atctcagaga ctgctttaaa cccaaatgag ctgtaaaaag gctcaagata
    17221 agcctgcgct tgagcgtaga cgggaagctt tggaaagtgc tgttgacaat aggctaaggc
    17281 ttgatgaact aagtcacgtc ctagtcctgt tcgccttgca ttttgtgcta ccagtactcg
    17341 tcccagcttt atgctattgt cagttgggat taagcgacag taggccctaa gctctgaatc
    17401 aacctgcttg aaaagatgga tagctttttg atccaaatcg tcaatatcag gatagggaca
    17461 ttgctgctca accacaaaaa cagccacacg ctctttatag atggcaaaca attcatcttt
    17521 tgttaactga tcaaatgctt taacaaccca cattagctag cctccaaaat cactggtaca
    17581 atttccttta tgataacata atagcatata tcagccataa tggaacgaaa aaaacctgac
    17641 tcttaatgga cgatgtcgtg atgataatta catcttgtct caaaagctgg taatcatcac
    17701 aggcacagaa aaatgtgccc cttctgttgc tttttgagaa aaagttcact tgctttttgg
    17761 tagttttttg gtatcatact aaaaaataga cttaattaag gagatacagc ttggaaacaa
    17821 aagatttaaa gaagcttgct aaagctgagc tgcactgcca tttagacggt tctttgtcat
    17881 tagacactat tcgtcagttg gcggctttgg cgcaggtaga tgttcctcaa gatgattctg
    17941 agttaaagca gctggtaacc gcaccggaaa cctgtgaatc cttgatggat tatttaaaaa
    18001 cctttgatgt tatcagacca ttattacaaa cgcctcaggc tttaacattg gctgcttatg
    18061 atgttgtgaa gcaggctgcc cttgaaaatg tcatctacat tgaaattcga tttgctcctg
    18121 agttgtcaat ggatcagggc ttgaccgcca ctcaggtggt agaggcagtt ttaaaaggac
    18181 tcgagcaagg acaaaaagag tttggcattg tcgctaaggc tattgtgtgt ggcatgcgtc
    18241 agtcctcact agacattagc agagagattt ttgcaaatgt cttagagtgg gccaataaag
    18301 gcttggtagg ctttgatttt gcaggcaacg agctggactt tcctccagct gtcttagcag
    18361 atttgatcaa agagacgcag gcctatgggt taccatttac gcttcatgct ggtgagtgtg
    18421 gctgtccaaa ctatattgtt gatgctattg atttaggtat caaacgctta gggcatgtga
    18481 cggccattca taaccaaaag gatttattgg ccaagtttat cgccaatgat gtgacagcag
    18541 agctgtgctt cactagtaat ctacaaacca aggctgctag gactgttgag gactttcctt
    18601 atatgcagct aaggcaggct ggcgctaaat tatccattaa cacagacaat cgaacagtat
    18661 ccgataccaa tctgacaaag gaatatgaac tgtttgtcaa gcactttgag acaagcgtca
    18721 cagacttttt agagcataat cgtgatgcta ttaaggctag ttttgccagt ccggctgaaa
    18781 aagaagcttt attggatcgt ttggaaaagg cttatcagtc ttacatcaag aaataatgct
    18841 tttcttggca aagtatgata aaatatactg acatttagtt attttgggag gaaattatgg
    18901 cattagccaa aatcgtttat gccagcatga caggaaatac tgaagaaatt gctgatattg
    18961 ttgctaataa attgcaagaa ttgggacatg atgttgaggt tgacgagtgt acaacagttg
    19021 atgcttcaga gcttgaggct gctgatatgg caatcgttgc gacctatacc tatggtgatg
    19081 gggacttacc agatgagatt gtcgactttt atgaggactt gcaggatttg gatttgtcag
    19141 gcaagatcta cggtgtcgtg ggctctggtg atacctttta tgattatttc tgcaaatcag
    19201 ttgatgattt tgacgaacag ctcgctgcca ctggtgccac taagggagct gactcggtta
    19261 aggttgattt agctgctgag gaagaggata ttgctcgcct agaatccttt gctgagcaaa
    19321 tgtcacaggc attagaggca taagtaagac ttttgataca gattggtaaa acggtcagtg
    19381 gaggcttgcg ttttttacca ccaaatgcat gaaaaactga tattttctga tcgttttttc
    19441 atgactatgt gctctttttc aagaaaagtc atgccattat tagcctgaat gcaaacaatt
    19501 gatagtgtca aaatgttgat catatagtaa aaaaatgcat gtgactagaa agcagttaca
    19561 tgcattttcg tcatgcgttt gtcgtgaggc attttggggg ttacttgctt actgagctga
    19621 aattcactat aataaaaaga taaataaaga aaagaagaag ttaggtgaat gatgggatta
    19681 gagaccatac gacaagacat taatgctgtt gatcgtcagt tgattgcttt gctggaaaag
    19741 agaatggtct tggctgacca agtagcggcc tataagcagg tacatgatgt gccagtgctt
    19801 gatcaagagc gagaggctga ggtcctaagg agcgtgtcac agcagattcg gcataaggcc
    19861 tttgagcctg ccattcttga gctatttaag acaattatgg cagtatcaag gcgttatcag
    19921 gctgagcaaa tagcggttgg ttcaaatgat gatgaagcct attaaaaaca atcaagacat
    19981 cagtataggt gataatgtct atttggcttt tgcagccctg ctcgttgggg tggtggtagg
    20041 tgtgatagat actgtttttg gacaaggctt gttgctcttg tctgctgttc gtgatgctca
    20101 tctcatttac ctgttaccct gcttagctct tgctggactt gtgattgtgt tcttatatga
    20161 gcaatatggc caaatcgcta agcaggggat gggcttagtt tttgatgtgg ggaatggtga
    20221 aaaaacaaga ctaccactgg tgttgattcc gttgattatc ctctcaacct ggctgacgca
    20281 tttatgtgga ggcagtgctg gtcgtgaagg cgtagcggtt caaattggag cgacaggtca
    20341 catttttttg gacgtcttag acatcttaag gacaagtcac agctgttttt agtcatggga
    20401 atggccgcag gctttgcggg cttatttcaa acgccaatga cagcggttgt ttttgcctta
    20461 gaggtcctgt tgctaggaaa tataagctat ttagccttgc taccttctct tatagcagcc
    20521 tttaccgcct cttggacctc tcattgccta ggcttagaaa aattttcagt cccgatagcc
    20581 aaggccttga aaatcacccc gataaccttt gggaaattag tgctactagg ccttattttt
    20641 ggcttggctg gtaatctttt tgcctccttg ttagcaaggg ctaagccata cattgcagca
    20701 aggctgccaa atccttatta tcgtgtgttg cttgttggtg gttttctatc gcttagcctg
    20761 ctgctgtgcc attacgggcg ctatagtggc ctagggacta acttaattac agcggccttt
    20821 agtcatcagc ctattgctaa ttatgattgg ctattaaagc tcttgtttac cattatcact
    20881 ctctcggctg gctttcaggg cggtgaggtc actccacttt ttgctattgg tgcggcttta
    20941 ggaattgtcc tagcaccatg gcttggcttg ccggctcagt tggctgcagc ccttggctat
    21001 gctgcggtat ttggcagtgc caccaatacc tttttagccc cgatatttgt tggattagag
    21061 gtttttggtg caacaaacgc aactgcttac tttatcgtga tagcctttgc ttatatggtg
    21121 agccgaaggc attcaatcta cactaagcaa agggtgacca ctagcatcgc ttcctagtgt
    21181 cttggtcagt tttttggaga aaatagcttt acaagtgggg cttattttgt tacaataggc
    21241 tccgtgtgta atggacgcac aaaaattacg gctaatccgc taagactcgc gcttaagatt
    21301 agtaagataa ggagaataaa caatgaatcc attaattcaa agcttgacag agggtcaact
    21361 tcgtactgat attcctagct tccgtcctgg tgacactgtt cgtgtgcacg caaaggttgt
    21421 cgaaggatct cgtgaacgta tccagatctt tgagggagta gtcatttcac gtaaaagtca
    21481 aggtatctca gagatgtata ctgttcgtaa gatttctagt ggtatcggtg tagagcgtac
    21541 cttcccaatt cacacaccac gtgttgaaaa gattgaggtt gtgcgtcatg gtaaggttcg
    21601 tcgtgctaag ctttactacc tacgtgcctt gcaaggtaag gcagcgcgta tcaaggaaat
    21661 tcgtcgctaa aaagagcata cgagaggttt ttcactgtct tatgaaagga ctgctggagc
    21721 agcagggtct ttgggacaag ctttttttcg caggtatgtg aacctacgct caattcaaga
    21781 catatcaaag gctcattcta tgatagagtg ggctttttga ttgtgatcat gctttagtgc
    21841 ctaaataaat gacagcagcc tgactaatga aaggcttact tgactttgga aatgctcaag
    21901 gcttgcgcta ccagatagaa gctgacatca tgccatagca gtcaagggga agaaggacta
    21961 gattttttgg cgaggtgttg atctgtgacc ctgatgttgt tgggaatatg agagtaattt
    22021 aaaatttcgt cttgcattct acctttttct aggttacaat agacaagtaa cctgattagt
    22081 gaagctaaaa gacgtagcga tgggttctaa aaaagaatga ttctggcgtt tttggctaac
    22141 ctaagctgat agctttgcta ggcagtgtct tagtcatctg gtcagtcctg ctagtttaac
    22201 ggataaaaca agcgcctcct aagcgctagc tgtgggttcg attcccgcgc gggacattaa
    22261 aaacaaagta aaaagagtct gagaaggttt gagctgcccc taattgttag atttttttct
    22321 aactcttgaa gtgtgggtca aagactattt gtctcaggac tctttttaat tggtttttac
    22381 taagctgctt catctagttc ttcagttgct aagttgtttc cttcttctgt atgttggttt
    22441 tcatcaagta gcattcctgt gcggtaatct aatgctgcca aaggtgatac attatccaga
    22501 acaactgagg ttataccata atgatcaacg gattctttgt tgcctcccaa tttgatttgg
    22561 aggagctctc cgttttgatc aattccaacg tactgtaaca ctacttgacg aggaactaat
    22621 tcatcattct gataaatagg agttacctta taatctagcc aaaagttagg gtgtatggct
    22681 aaccaattgt ctagtctatt ttcataataa agcattccta aaggattttt atcactaaaa
    22741 cctgtattaa ggtattttgt catagtaact aaatttttgg gttcatcatt taggccgcta
    22801 aactgataac cgactagatg tccgcgatcc attaaccaag tctttttccc tctagaatta
    22861 atgacttgat agttatgcca gccgggagga ttaaatctaa gcgcttttct tttgagagtt
    22921 ggttcatctt gatctttgag ttgtatgtgt gcataggtgg ctctttgtaa atgatcaaga
    22981 tctcccagag ctatttggta ttttccagta aacggtaaaa ttcctggtat ttcggtagct
    23041 tttgttccca atgatatttc cgttgtatct gggaaggttc taagttttct tgcagattga
    23101 acagagttag ctgtgaaaat agtcagaata gttaacaaaa caattgttag acttttccag
    23161 ttacggcgac gtgatttaga catatcaatg ccctcctttt tttg
//
LOCUS       DARYVE010000027        23058 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYVE010000027 DARYVE010000000
VERSION     DARYVE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23058
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            102..1115
                     /gene="pfkA"
                     /locus_tag="TVW25_001035"
     CDS             102..1115
                     /gene="pfkA"
                     /locus_tag="TVW25_001035"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1378674.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            1177..2679
                     /gene="pyk"
                     /locus_tag="TVW25_001036"
     CDS             1177..2679
                     /gene="pyk"
                     /locus_tag="TVW25_001036"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1378675.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            2808..3365
                     /gene="lepB"
                     /locus_tag="TVW25_001037"
     CDS             2808..3365
                     /gene="lepB"
                     /locus_tag="TVW25_001037"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1378676.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            3542..5353
                     /gene="glmS"
                     /locus_tag="TVW25_001038"
     CDS             3542..5353
                     /gene="glmS"
                     /locus_tag="TVW25_001038"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1378677.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            5537..5872
                     /locus_tag="TVW25_001039"
     CDS             5537..5872
                     /locus_tag="TVW25_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1378678.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            5979..6620
                     /locus_tag="TVW25_001040"
     CDS             5979..6620
                     /locus_tag="TVW25_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1378679.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            6630..7259
                     /locus_tag="TVW25_001041"
     CDS             6630..7259
                     /locus_tag="TVW25_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1378680.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            7276..8112
                     /locus_tag="TVW25_001042"
     CDS             7276..8112
                     /locus_tag="TVW25_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1378681.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(8208..9446)
                     /locus_tag="TVW25_001043"
     CDS             complement(8208..9446)
                     /locus_tag="TVW25_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1378682.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(9549..10883)
                     /locus_tag="TVW25_001044"
     CDS             complement(9549..10883)
                     /locus_tag="TVW25_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1378683.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(11012..11098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            11363..13654
                     /gene="pcrA"
                     /locus_tag="TVW25_001045"
     CDS             11363..13654
                     /gene="pcrA"
                     /locus_tag="TVW25_001045"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1378684.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
     gene            14067..14312
                     /locus_tag="TVW25_001046"
     CDS             14067..14312
                     /locus_tag="TVW25_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1378685.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            14360..14941
                     /gene="amaP"
                     /locus_tag="TVW25_001047"
     CDS             14360..14941
                     /gene="amaP"
                     /locus_tag="TVW25_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1378686.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            14951..15139
                     /locus_tag="TVW25_001048"
     CDS             14951..15139
                     /locus_tag="TVW25_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1378687.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            15152..15691
                     /locus_tag="TVW25_001049"
     CDS             15152..15691
                     /locus_tag="TVW25_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1378688.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            15729..15926
                     /locus_tag="TVW25_001050"
     CDS             15729..15926
                     /locus_tag="TVW25_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1378689.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            15936..16424
                     /locus_tag="TVW25_001051"
     CDS             15936..16424
                     /locus_tag="TVW25_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1378690.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            16580..17221
                     /locus_tag="TVW25_001052"
     CDS             16580..17221
                     /locus_tag="TVW25_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1378691.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(17338..17886)
                     /locus_tag="TVW25_001053"
     CDS             complement(17338..17886)
                     /locus_tag="TVW25_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1378692.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            18009..18710
                     /locus_tag="TVW25_001054"
     CDS             18009..18710
                     /locus_tag="TVW25_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378693.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            18722..21361
                     /locus_tag="TVW25_001055"
     CDS             18722..21361
                     /locus_tag="TVW25_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1378694.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILASHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            21437..22033
                     /locus_tag="TVW25_001056"
     CDS             21437..22033
                     /locus_tag="TVW25_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1378695.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            22043..23005
                     /locus_tag="TVW25_001057"
     CDS             22043..23005
                     /locus_tag="TVW25_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1378696.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         6708 a         4175 c         5391 g         6784 t
ORIGIN      
        1 gttgaaaacg gtttttcgat aaaaatagcg aattagtgaa gtaatttgca aacgaatgtg
       61 ctataataaa aacgttaaat taattaaagg agtaccaaaa aatgaaacgt attgctgttt
      121 taaccagtgg tggtgacgcc cctggtatga atgctgctat tcgtgcagtt gttcgtaaag
      181 caatttcaga aggaatggaa gtctatggta ttaaccgcgg ctatgctggt atggttgatg
      241 gtgatatctt tccactaggc tcaaaagagg ttggtgataa gatttctcgc ggcgggacct
      301 tcctttattc agctcgctac ccagagtttg ctcagcttga ggggcaattg gctggtattg
      361 agcagctaaa aaagcatggc attgaagggg tagttgtcat tggtggtgat ggttcttacc
      421 atggtgcgat gcgcttgact gagcatggct tccctgcagt aggtatccca gggacgattg
      481 ataacgatat tgctggaaca gactatacta tcggatttga cactgcggtc aatactgcgg
      541 tagaggctat tgataagctt cgcgatacct catcaagtca tggacggacc tttgttgttg
      601 aagtgatggg acgcaatgca ggtgatatcg cactttgggc aggtattgca agtggagcag
      661 atcaaatcat cgttcctgaa gaggaatttg acattcataa agtggtctca acaattaaag
      721 acgattttga aaatagagga aaaaatcacc atattatcgt tttagctgag ggtgttatga
      781 gtggcgaggc ctttgcgcag cagctaaaag aagctggaga tgaaagtgac cttcgtgtga
      841 caaaccttgg tcatatcctt cgcggtggct ctccaactgc gcgtgatcgt gtgattgcgt
      901 catggatggg agcgcacgct gttgagttgc tcaaggaagg caaaggtggc ttggctgttg
      961 gtattcataa tgaagagctt gttgaaagtc cgattcttgg aagtgcagag gacggtgcct
     1021 tgttcagcct tactgatgag ggtaacattg ttgttaataa cccgcacaag gctcgcttag
     1081 actatgctgc tttgaaccgt tcattagcac aataggataa gtaagatctg gtaatctttg
     1141 ttaatcaact aaaaaataag ggagtttcat aataaaatga ataaacgtgt aaaaattgtt
     1201 gcaacacttg gtcctgcggt tgaaattcgc ggtggtaaaa aatatggtga ggacggctat
     1261 tgggctggtc agttggacgt tgaacaatca gctaaaaaga tcgctgaatt gattgaagca
     1321 ggtgctaatg ttttccgctt taacttctca catggtgacc acaaagagca gggtgaccgt
     1381 atggctactg ttcgtcttgc tgaaaagctg gcacgtcaaa aggttggttt ccttttggat
     1441 acaaaaggac cagaaatgcg tacagaattg tttgctgacg atgccaaaga atatagctat
     1501 gtgactggtg agcgtattcg tgttgcgaca gcacaaggca ttcaatcaac tcgtgatatg
     1561 attgccttga atgtagctgg tgctcttgat atttatgatg aggttgaggt tggccacact
     1621 attcttattg acgatggaaa gcttggctta aaggttatcg agaaggacat tgcaaagcgt
     1681 gagttcatcg ttgaggttga aaatgatggc atcattgcaa agcaaaaggg tgttaatatc
     1741 cctaatacca agattccttt cccagcctta gcagaacgtg ataatgctga tattcgtttt
     1801 ggtcttgagc aaggtcttaa ctttattgct atttcatttg ttcgtactgc caaggacgtt
     1861 gaagaggttc gtgagatttg tcgtgaaaca ggcaatgagc atgttcaatt atttgctaaa
     1921 atcgaaaacc aacaaggtat tgataacctt gatgaaatca tcgaagctgc agatggtatc
     1981 atgattgctc gtggtgatat ggggattgag gtgccatttg aaatggttcc agtcttccaa
     2041 aaaatgatta tcaccaaggt aaatgcagca ggtaaagcag tcatcaccgc aactaacatg
     2101 cttgaaacaa tgactgaaaa accacgtgca actcgttcag aggtatctga cgttttcaac
     2161 gcggttattg acggtacaga tgcgacaatg ctttctggtg aatcagcaaa tggtaaatac
     2221 cctgttgaag cagttcgtac aatggctaca attgataaaa atgcacaaac tcttcttaat
     2281 gagtatggtc gtttagattc atctgccttc ccacgtacca ataaaactga cgtgattgct
     2341 tcagctgtta aagatgcaac acactcaatg gatatcaagc ttgttgtgac catcactgaa
     2401 acaggaaaca cagctcgtgc catttctaag ttccgtcctg atgctgacat cttggctgtg
     2461 acctttgatg aaaaggttca acgtgccttg atgattaact ggggtgtgat tccagtgctt
     2521 gctgaaagac cagcatcaac agatgatatg tttgaggtag cagagcgtgt agctcttgag
     2581 actggtttgg tgcaatcagg agataatatc gttattgttg caggtgtgcc agttggtaca
     2641 ggtggtacaa atacaatgcg tgttcgcact gtaaaataat agctttccat aagctttagc
     2701 tattttgctc tatcagataa tttaaggcaa acaatgatac ttaaaaattg tttgcttttt
     2761 ttattagtca tatcatgtta taatgagact atagactagg agttattatg gtaaagcgag
     2821 attttataag aaatatattg ttgttattga ttcttattgt gggagctgtc cttcttagaa
     2881 tatttgtttt ttcgacctat cgagtcacgt cagaggcttc aaatgcctat ttgaataagg
     2941 gcgatttaat caccattaag aaaaatattg agcctaaata taaggatttt gtggtttata
     3001 cggttgacaa aaaggattat gtgagccggg ttgtagcagt agcaggtgat cgtgttacct
     3061 atatggacga tattttttac ctgaacaata tggttgaatc ccaatcctac cttgagagta
     3121 tgaaggcaaa gtatctcaat catgccccta ttggtacgct ttatacggag gattttacga
     3181 tttcgacggt tacttctgga aaatacgata gcattcccaa ggggaaatac cttttgctaa
     3241 atgataacag aaaaaaccat catgatagcc gtcagtttgg cttaattgac gtgtcacaaa
     3301 ttaagggatt agtaacattt agagtgcttc ctttgaaaga ctttggattt gtagaggtag
     3361 agtagcttta aggctgctct attttgtttc tcaaaatatg actataccaa ttttcttgtt
     3421 gacaagattt ttctgaagtt atatactcta aatataacgt tttagtcggt ttatatctga
     3481 ctataccaat tatattgatc attaaagaaa gtagtaagct agcttactga ggtgttaagt
     3541 tatgtgtgga attgttggag ttgtaggtag tcgtaatgcg actgacatct tgatgcaggg
     3601 attggaaaaa ttagagtatc gtggttatga ttcagctggt atttttgtgt cagatggcag
     3661 gacgtccaat ttggtaaaat ctgttggacg cattgcagat ttacgctcta agattggcat
     3721 tgatgttgtt ggaacgaccg gtattggtca tacacgttgg gcaacgcatg gtcaagcaac
     3781 agaggaaaat gctcaccctc atacctctca gacaggtcgc tttgttcttg ttcataatgg
     3841 tgtgattgaa aattacctcc agatgaagga gcagtacctt gctggacaca cgtttaaagg
     3901 acaaacagac accgaaattg cagttcattt gattggagca tttgttgaag aaggctgttc
     3961 agtcttagag gcttttaaaa aggctttatc aatcattgaa ggctcctatg cctttgcttt
     4021 gattgataca gaggatatgg atacgatcta tgtcgctaag aataaatccc cattgctgat
     4081 tggccttggt gagggctata acatggtttg ttcagacgct atggccatga ttcgtgaaac
     4141 cagcgaattt atggaaatcc atgacaagga gctggttatc ctgacaaagg attcagcaag
     4201 ggtgacagat tatgctggca atccgattga tcgtcagtca tatacagcag agcttgatct
     4261 ttcagatatt ggcaagggga cctatccatt ttatatgcta aaggaaattg acgagcagcc
     4321 aacagtgatg cgtcgcttga tttcaaccta tgcagacgcc aagggacaga tgatgattga
     4381 tccagctatc ataaggtctg tccaagaggc tgatcgtatc tatattcttg cagctgggac
     4441 ctcttatcat gctggctttg cttctaagtc aatgctggag catttgactg atacacctgt
     4501 tgaattaggg gttgcttctg agtggggcta caatatgccg ctattgagca aaaagccaat
     4561 gtttatcctc ttgagccagt ccggtgagac agcagatagc cgtcaggttt tggtcaaggc
     4621 aaatgagatg gggattccaa gcctaacagt gacaaatgtt cctggctcaa ccctatcacg
     4681 tgaagcaacc tacactatgc tgctccatgc aggtccagaa attgcagttg catcaactaa
     4741 agcctacaca gcacaggtcg ctgcacttgc ctttctagct aaggcagttg gtgaggctaa
     4801 tggcaagaag gaagctatta gctttgattt ggttcatgaa ttgtcattgg tcgctcagtc
     4861 tattgaggcc accttatctg acaaggagct gattgctgag aaggtgcaga ccttattggc
     4921 aacaacacgc aatgcgtttt acattggtcg tggcaatgat tattatgttg ctatggaggc
     4981 tgcactaaaa ttaaaagaaa tttcatacat tcagtgtgaa gggtttgcag ctggtgagct
     5041 aaagcatggg actatttcac tgattgagga tggcacacct gttattggac ttatttcttc
     5101 aagtgagctg gttgctgcac atacacgtgg caatatccaa gaggtggctg cacgtggcgc
     5161 tcatgtgttg acagttgttg aggagggctt agagcgtgag ggagatgaca ttattattaa
     5221 taaggtgcac ccattcttag cgccgattgc tatggttatt ccgactcaat taattgctta
     5281 ctatgcttcc ttgcagcgtg gtttagatgt agataagcct cgtaatttag ccaaggctgt
     5341 tacagttgag taatagttgc ctgcttaaaa tgaggcagca gggtcctgaa gcctatttga
     5401 aacgagcttg acatgatgtt atgtcaggct cgttttttag tgcttgcctg gtcttatgat
     5461 aacgtattca tcttgtcaaa taagcatttc tgaagtaaaa tattaacgtt aagactaaga
     5521 agcttaggag agtaagatga cgttaccaaa ttgtttacaa tgcgattcag aatatgttta
     5581 tgaggacggg catttgctca tttgtccgat gtgttccttt gaatggacac gtggtgagga
     5641 ggagcctgag gaggaggggc ttgtcgtttt agatagtaat ggaactagat tagctgatgg
     5701 agacactgtt acgatcatta aggacctgaa ggtcaaggga gcgccgaagg atctcaagca
     5761 gggaactcgt gttaagcata ttcgtcttgt tgaaggtgat cacaatattg attgtaagat
     5821 tgatggcttt ggtgcaatga agctaaaatc agaattcgtc aagaagattt aataacaata
     5881 agcaaccaga tgactggttg tatttttata gaaaagtact tttcaatcca tcagaaaatt
     5941 tggtataatg gataaactat ttatatctag gagacaacat gacgtatatt atgcaggttt
     6001 tacccagctt gctggatggt gccttaatca ctttacaggt tttctttatt gtaattgtat
     6061 tatccattcc cttaggggct cttttagctt ttttgatgag ggttgacttt aagcccttgc
     6121 agtggctatt gacgctctat atttgggtca tgaggggaac acccttattg ttacagctca
     6181 tcttttttta ttatgttttg ccaagtgtgg gtgttacctt tgatcgtatg ccggcagcga
     6241 ttttggcttt taccttaaac tatgctgctt attttgccga gatttttcgt ggcgggatag
     6301 agactattcc aaatgggcaa tatgaggctg caaaggtgct gaagcttagt ccggtacaaa
     6361 ctgttcgcta tgttatcttg cctcaggtgt tcaagattgt tttaccaagt gttttcaatg
     6421 aggtgattaa cttagttaag gattcttcct tggtatatgt gttaggagta ggggatttgc
     6481 tattagcaag caagactgcg gcaaatagag atgcaacctt agcaccgatg tttattgcag
     6541 gtttgattta tttgctctta attggtttgg tcaccatttt atcgaagcag gttgaaaaaa
     6601 gatttaatta ttatcagtaa gggggtcata tgttagaact gaacaatatt tcaaagcgat
     6661 ttggtcacaa gcagatcttt gatggctttc atttgaccgt tgaagatggt gaggttttat
     6721 ctttggtagg gccatctggt ggtggcaaga ctactctgct ccgaatgctg gctggcttag
     6781 agcctattga ttcgggaaat attagctata atggcgagtc tgttcctatt gatcatttag
     6841 aaaaaagaag cctgcttggt tttgtttttc aggatttcca attgtttcca catttgacgg
     6901 tgctggataa tctcatcttg tctcctacca ttaccatggc tatgccaagg cctgatgcaa
     6961 agcaaaaggc tatggagctg ctggagcgcc taggtctcaa agagcatgca gctgcttatc
     7021 cttatgcgct atctggtggg caaaagcaaa gagttgcctt ggctagagcg atgatgattg
     7081 acccacagat tgtaggctat gatgagccga caagtgcctt agactctgaa ttacgtcagg
     7141 aggttgagaa attgattttg caaaatcgtg agatgggcat tacccagatt gttgtcaccc
     7201 atgatttgca gtttgctcag accatttctg atcgtatcat caagatcaat cctaaataga
     7261 agaagaggta gtgctatgac gttaaaaaag acccttctag tagccctatt tgctgctaca
     7321 gctacgcttt tagtagcttg tggcgctagt aataaacaga ctagctcaga tgcttgggat
     7381 tcctacaagc agaaaaagac gattacgctt ggctttgata atacttttgt gccaatgggc
     7441 tataaggacg agtcaggaaa aaataccggc tttgatattg agctagcaaa ggctgttttt
     7501 gaccaatatg gtatcaatgt taagtatcaa gccattaact gggatctcaa agaaactgag
     7561 ttgaacaatg gtaaaattga cctgatttgg aatggctatt ctgtgacaaa agagcgccaa
     7621 gctaaggtgg cctttacaga gccttatatg aaaaatgagc aagtcttagt gacgcaaaaa
     7681 tcatcgcaaa taagctcatt tgctgatatg aaaaataaga ccttaggtgc ccagtctggc
     7741 tcatctggct atgatgcctt tacgagtcat cctaaggtgc taaaggatct tgtcaaggga
     7801 aatgacgcta cccaatatga aacctttaca caagccttta tcgatttaaa aaacaagcgt
     7861 attgatggcc ttttgattga tagggtttat gccaattatt accttcagca agaaggtgag
     7921 ctagaccgct ataacattat cgcgagtgag tttgaaggtg aggattttgc agttggtgtc
     7981 cgaaaagcgg ataaaaccct acaaaaaaag attacacaag ccttaaaatc gctttatcag
     8041 gacggtacct tccaaaaaat ctctaaaaaa tggtttggtg aagatgtcgc aacagttcag
     8101 ttgaaatcat aagacgcaag caagacctaa tcagctcaga ggggttgaga ctagatacat
     8161 ttaaaagact taccttctaa aggcaagtct ttttatacgg cttattatta gctgatacgc
     8221 ttgatatgat agtgtttttt aattgctatg gagtttgtta ttggtgtgat ttgatgatat
     8281 atcaggtgcc aagcttcgtg tcgtctccag atactggtat gctgattgcc ctgtagctga
     8341 taggtgacta gcttggtgtt gtggctgatg gattgcatac aaaaggcttc aagctgattg
     8401 gaagaagaac gctgctgctc taaaaattgc ttggcattgt aagcttgtcc atcgcgatca
     8461 ataaaggtaa aggtcttggc aatgagctct tgataatctg ggatttgact tagcatgatt
     8521 ttctcgtttt tgtagagctt tttgtaaaca tattcacagt tgtcatcttt aggaagcttt
     8581 gcaggctcaa catgaatatc aatatcataa acagcaaatt gctcactcaa gagctgttcg
     8641 acctgctcgg ttatggcgtg actttcataa acagaaaggt cagggtgcat ctcaaggaca
     8701 atatctaaat agacattgct tccgtaagtg cggccgcgct gtgatttgac agcaatgatt
     8761 ttgggaattt tcaatatggc cttttcatat gctttgagct gcgtgctgtc aaagccatct
     8821 gataagctaa aggcgcttgc cataaaaata tcaaaggctg tttttagaat gaaaaaggta
     8881 atgataaggg cagccagcct atcaataata ggtagcttta aggaagcggc gataatagca
     8941 atagaggttc caatagaggt cacagcatca gaaagattat ctttagaggc tgcaaccaag
     9001 gcactggatc ttaccttttt tgataacgct ttattaaaag catatactcc aagcatcaca
     9061 agggctgaag cgatcccaac aatagcacct aatggatcga tagcagactg cttaccacta
     9121 atcatctgtt gaatagtttg caggagaacc tgaaagccaa caatgaacat gataaaggag
     9181 gttattaagc ttgaaaggtc ttcgattttc cagtggccaa agcggtgatt ggcgtctgct
     9241 ggctggctgg ccagatgaag tccgatgagc agagtgacat taccaacgat atcagacagg
     9301 ttgttgaagc catcggcaat caaggagctg gcatttaaaa gatagccagc aagaagcttt
     9361 gtgatgctaa gggccaaata ggtaacaatg ctaacaatgg gccctctttt tgctaaccga
     9421 aggttttcta ctggattgtt tggcataaaa actcctttgt aactgatgct ttcattatat
     9481 cataaaagct aagacaagct aaaagcctag agctatccta aatagggtat tccaggcttt
     9541 tcgatagctt atttggtgct ttggcgctta aaatatgccc ttgtctcaaa aatgacaaca
     9601 ggagataagg ctagtagggc gataagattt ggcagagcca tcaggccatt gacaatatct
     9661 gccagtatcc aaatcaactc cagcttaaga aagccaccaa gtcctaccat gataacaaag
     9721 atcaggcgaa aatagctgag gtgtgtcgtg ccaaataaaa agataaagca gcgctcacca
     9781 taatagctcc agccgagaat agtcgtaaaa gcaaaaagaa caagcgacag ggtcaaggca
     9841 taggtgccca tatgcccaaa gatagaagca aaggcagact gtgttaaggg tgctccctct
     9901 agtgcgctag tccactgacc agttaccaaa atggccagac cagtcagagt gcagatgatg
     9961 atcgtgtcaa taaaggttcc ggtcatagaa atcaggccct gttctactgg ctccttggtt
    10021 ttagcggcag cagcagcgat cggagcagag cctagtcctg attcgttaga aaaaacccca
    10081 cgtgcaatac ccttttgaat ggcgtcctta accaagcttc cggcaaagcc ccctatagct
    10141 gctgtagggg taatagcgga cttaaagata aggacaagca taggaagaag cttagtatag
    10201 tgaacagcaa taaccgttaa gcttgctcca atataaaaga tagccatgaa aggaacgact
    10261 gtttcagcca ccttggcaat agcttgaatg cctccaaaaa taatcatggc cacaacagca
    10321 gctagcaaga cactgattaa tggcgaagag atcccaaggc tatggtgtag ggatgaggta
    10381 atcgcattga cctgagcaaa tgtcccgatt ccaaacaaag ccactaaaat accagagaca
    10441 gcaaataagt tggctagagg cctccatttt tgccccatac catttaaaat gtagtacata
    10501 ggtccgcctg aaatctgacc attagcgtcc ttagtacggt atttaatggc taaaacgccc
    10561 tcggaatatt tggttgccat accaaagaag gcagcaaccc acatccaaaa aagtgcccca
    10621 ggtccaccag actttatagc ggttgcgaca ccaacaatat taccagtacc aactgtagca
    10681 gctagggctg ttgctagagc agcaaatgat gaaatatctc cttgcccctc attcttagca
    10741 aaaatgagcc taaaggcctt aggcaacttg atgacttgga gaaggctaag tctgctggtg
    10801 aggtaaatgc cagtaccaag cagcagtagc aacaagggtg ctccccaaac caaatcgtct
    10861 atccattttg cagcagctat catgcttaat tcctcaactc tcttaaccaa tgctgccaaa
    10921 agaaaaagcc acccctgcgg atagcctctg aagcatatga caaaacagca agcacaaaaa
    10981 atgctaagga agcatgatca tacggcttga tattttatct tctgtccttt tgcctgagag
    11041 attgagcagt cttgccttgc cccttcggcg cctaataggt ctctccagaa gcccgtccgt
    11101 caagcagtcc cgtccaacac ctgaacacct gagagtataa ctccttcggc gaaatccatt
    11161 cttctcctgc atgacatcat tcggtttatt aaattatgtc tatgataccc aaaaagccta
    11221 gtgatgtcaa caagcaattt aactgatggc taactccttg tttttatggt aacatcattg
    11281 tcctcttttt tctttttgac tgaaacatga tataatcgta aggttaataa aagtcactta
    11341 ttagacgata tgaggagaaa gcatgaatcc tttattagat ggaatgaatg ataaacaagc
    11401 agaggcagtt caaacgactg agggcccctt gttaattatg gctggtgccg gttctgggaa
    11461 aacgagggta ttaacccacc gcattgccta cttgattgat gaaaagtatg ttaatccctg
    11521 gaatattttg gcgattacct ttactaataa ggctgcgcgt gagatgcgag aaagggcatt
    11581 ggccttaagc ccagccacca aggatacctt gattgcgacc tttcactcaa tgtgtgttcg
    11641 tattttacgc cgtgaggcag atcatattgg ctacaatcgg aatttcacga ttgttgatcc
    11701 aggagaacag cggaccttaa tgaagagaat agtaaaagct ctaaatctgg atcctaagaa
    11761 atggagcgag cggtcgattt tagccaccat ttcaaatgct aaaaatgatc tcttagatga
    11821 aagagcctat gagctaggag cctctgattt gtatagccag acagttgccc gctgctacaa
    11881 ggcctatcag gaggagctca gacgaagtga ggctatggat tttgatgatt tgattatgat
    11941 gaccttacgc ctatttgatc aaaatcctga cgttctagcc tattatcagc agcgttatca
    12001 atatatacat gtcgatgaat accaagacac aaaccacgct caatatcagc tagtgactct
    12061 tttagcctca cgctttaaaa atatttgtgt tgtcggtgat gcagaccagt ccatttatgg
    12121 ctggcgtggt gctgatatgc aaaatatttt agattttgaa aaggattacc ctgatgcaag
    12181 ggtggttttg ctggaagaaa attatcgctc caccaagaaa atccttcagg cagctaacga
    12241 ggtgattcag cataatcgtc atcgtcgtcc gaaaaaattg tggactcaaa acgcagacgg
    12301 tgagcagatt gtttattata gggcaaatga tgagcgtgac gaggctgttt ttgttgcctc
    12361 aaccatcagc aatatgtgtc tagagctagg aaagagcttt aaagactttg ctgttttata
    12421 tcgtaccaat gctcagtccc gtacgattga agaagccttg ttaaaatcaa atattcccta
    12481 cacgatggtc ggaggaacca aattctacag cagaaaggaa attcgtgatg tgattgccta
    12541 tttgactgtg gttgctaatc cgtcagataa tctctccttt gaacgaattg tgaatgagcc
    12601 taaacgaggg gtagggccag gaaccctaga taagctccgc caatttgctt atgggcaagg
    12661 acagtcattg ttagaggccg cttcaagcct tgagcaatca ccgctaaaag gaaaggctgc
    12721 ccaagccatg ctggccttag cgagtctctt aagtgatttg agagctgatt tagaccagct
    12781 gagcattaca gccctggccg aggccttgct ggagaaaacc ggctatctgg atatgctgcg
    12841 cgtccaaaat accttagaaa gtcaagctag gattgaaaat attgaagaat tcctgtctgt
    12901 taccaaaagc tttgatgacc tatcagcaca gcagcaggag catgaagcag gtattgatcg
    12961 cttaggaaga tttctcaatg accttgcttt gattgctgat agtgatgatg gcaatgcaga
    13021 aaccgctgag gtaactttga tgactctgca tgcagctaag gggctagaat ttcctgttgt
    13081 ttttctcata ggtatggagg agggagtctt tcctttagcc cgagcagccg aggatcaaga
    13141 tgagctagaa gaagaaaggc gactagccta tgttggcatt accagagccg aggaatgctt
    13201 gtttttaacg aatgccaata cacgtaccct atttggtaaa agcagctata atcgcccaac
    13261 aaggttttta aaagagatgt cagagaacct tttaagcttc caaggcttgg caagacctgc
    13321 tcatgcttcc tttggtgtga cattttcgca gcagggtcaa cgacaatttg gcacaggaat
    13381 gagtctatca gaggctatcc agtccagaaa atcaatggca cagcctgcca gagcagcctc
    13441 aacatctaca ccgctgccct ttggaccgaa tgcagctact tcaaagcaag ccgttgattg
    13501 gcagattggt gatattgccc atcataaaaa atggggtgct ggaacggttt tagaggtcaa
    13561 gggatctggt aagaccatgg aattaaccat tagttttcct gatgtcggat taaaaaaact
    13621 ccttgccagc gttgctccta ttgaaaaaaa ataaaaggta cagcttatgg gcaatttgca
    13681 tagtcacttg gataagggct ttgcaattgc ggtttagttc tgcgatttaa gaaaagaagt
    13741 aagcaaggat tttatcagtt aaccacatac caagcttttg atggccttga tgccggagag
    13801 agcttggtat ttttttattt ttaaaaaaat cacaaaaaat gatttattct gagcataatc
    13861 cttgcaaatt aaaatgagaa gcgtataatg gcaatataaa ttaaataaca agtggtcact
    13921 tttgttaata gttgttttaa ggtatttgta gcgctttatt gttaaacata aatgtatcaa
    13981 aaaaataact agcaatttta tatttaattt atgtagtcac tttaaagagt gaacaaagta
    14041 gttttattga attgaggaga tttattatgg gaattatttg gacattaatt gtgggtgcac
    14101 ttatcggtgc tattgccggt gcgcttacta aaaaaggcgg atcaatgggc tggattgcca
    14161 atatcgctgc aggacttatt ggatcatacg ttggtcaagc tttgtttggc agctggggtc
    14221 taacattagc tggcatggca cttttcccat caatcattgg tgctgttatc gttgttatca
    14281 ttacttcttt tgtactaaat aaatcaaact aagggcattt ctatcattat agagatggtt
    14341 gagtaggaaa gaggttttta tgtcgaaatt tttaaaaatt agctatagtc tcattggctt
    14401 agtcctattg acggtctttg gtggcgtgat agccataact ggagattata ttaggctacc
    14461 tattggctat caatggcttc actgggatat gaattggctt cctaaattcc taaatccggc
    14521 cttatattac tattactttt gggcagctat cgctttattt ctaataacag tgctgatcct
    14581 tcttgtgatt atcttttatc cacgcaccta tactgagatt cagctggcta aggataaagg
    14641 aaccctgctt ttgaaagggt ctgctattga aggctatgta gcagctgcta ttaaagcagc
    14701 agggcttatg tcaagcccaa gagttaccgc taagctgtac aagcgtaaat ttaaggttaa
    14761 tgtcagtgga caattagctt ctcgcgtagc tgtcactgag cagctaaatg gcattaaaga
    14821 aggaattgag actggtttaa cagaattctt tggtattaat cgacctgtcc atttcaaggt
    14881 ttatgtcaag gatattgctg atgctaagca aaagcatagc tctaagagac gtgtagaata
    14941 ggagattatc atggcatttt atgaacggtt taaataccct attattggtg gtctgatagg
    15001 gctgatagct gctgtattac tgatgacctt tgggttattt aaaacactgc tggcaattat
    15061 tttcattatt ttaggagtat atggcggcct gtatgccaaa aagacaggta ttatcgatca
    15121 attgatcaaa cgtaactaaa ggagatttat catgactgaa acttacatta aaaacacaac
    15181 tcataaagaa ccaacttcag ctgttcgtgg cgaattgacc tatgatgaca aggtcattga
    15241 aaagatcgtt ggcttggctc ttgaaaacat tgatggccta ctaggtgtta atggtggctt
    15301 tttggccaat ctaaaagaca agcttgttaa tagtgattct gttcgtgatg gggttaatgt
    15361 tgaggttggt aaaaaagagg ttgctgttga tttagacatt gtagcagaat accaaaagca
    15421 tgttccaacc atttttgatg cgattaaatc tgtcgtagaa aatgaagtca agagaatgac
    15481 agatttagag gtgattgagg ttaatgttaa ggttgttgac attaaaacca aggagcaatt
    15541 tgaagctgat aaggtcagcc tacaggataa ggtgactgag gtagctcgct caacctctga
    15601 atttacaagc aagcaggtag acaatgttaa ggcatctgta ggtgcaggtg tagaaaaggt
    15661 tcaagagcaa actgagccac gcgttaagta agctaggctg tcaaacgata gaaatagagg
    15721 aaatcataat gtcagaagaa aaggtaaatg caaaattgga gcaagcaggc ggtaaaatca
    15781 aagaagcctt tggaaaggtg actggtgata aatccttaga aaccgaaggt aaggttgatc
    15841 aagcagccag caaaatcaaa gaagtagctg ctgatgctaa ggacgctgtc aagggctttg
    15901 ttaagggcct taagcaagat aaataaggag ttgtaatgaa agcaaaggac ataaaaagta
    15961 cgttgaccta cgatgataag gtcattgaaa aaatcgttgg acatgcttta gagaaggtca
    16021 gtggcttatt agcagtcaat ggtggctttt tctcaaatat caaaaataac ctagtgaata
    16081 gtgactctgt tcgtgatggg gtgtctgttg aggttggcag caaggaagtg gctgttgact
    16141 tagatattgt tgttgaatat ggtaaggata ttccagcaat tgttgagtct atcaaggcta
    16201 ttgtttttca aaatgtcgat agcatgacac atttgagggt cgttgaagta aatgtgaacg
    16261 ttgttgatat tagaaccaaa gaagagcatg aggctgctag cgtcactgtt caagacaggc
    16321 taacagacgc ggcctcagca acctctcaat ttgtagctga gcaagcagac aaggtaaaag
    16381 aaactgtctc taaaaccaca gataataacg agacagtaga ataaaacaca acaactaaaa
    16441 ctcctgttaa tgacatattg tgggctggtg tgatgaccag ctctttttat cagtgcttga
    16501 acaatgttat gctattgtat tctctgtgaa aatgtgattt aatgggaatg gtatcatttg
    16561 ttaaaaagga gtaattatca tgactagtaa taagagagag attactaatt ccaagtatca
    16621 aaagattgcc atttcagttg ctgaaaggat tgccaatggc gaatatgaag tgggagaaaa
    16681 gctaaagtct aggacaacca ttgcttcgac ctttaaagtt tcgcctgaaa ctgctagaaa
    16741 gggtctgaat attttagctg atctgaagat tttgacctta aagcatggga gtggcgccat
    16801 tgtcttgtct aaggaaaagg ctattgattt tctgaaccaa tacgaatcca cccattctat
    16861 cgctgtcatc aaagaaaata ttcgccataa tattcgtgag caggaaaagg caatggagca
    16921 tttaacagtg cttgttaatg agtttctgat gcaaagccaa tcaatcagca agcaataccc
    16981 gctggcacct tacgaaatta tttgtagtca ggattcagag cattttggcc aatccattgg
    17041 tgatttgaac atttggcatc aaacgggagc gacgattgta gctattgagc atgatggcca
    17101 attcattgtt tctcccggtc cttacgctgt tatcgaaaaa ggtgatcata tttactttgt
    17161 cggtaatgag gacgtgattt ctagaatgaa aacctttttt aatgttagaa agggtctgta
    17221 atcacaaaaa aacacagagc tgctttaagg tgatggtgat atcacgatga agtgtctctg
    17281 tgtttttgtg ttatcaggct aaggcttcta agtagcttat agctctgatt gaagccccta
    17341 gattactttt tcaaagccaa cagttttcag gataatagct gtcatgtcat cggttgtttc
    17401 ttgacagtca tgactaatcc agtagctaat cagactttca atactggcta gataaacctc
    17461 aagcgcgtag tgataaggga tctgatagtg cttggtgatg atttcttgaa agccatcaat
    17521 agtggtcaaa aattgataaa taaaatcctt gagtatttgt gaaaaattca aataactgga
    17581 gttagccata gcagcaataa agggaagatt atcaatgata taagcgaggg cttcctttag
    17641 aacgagtcta gtatctgtaa aaatatgagg gtcatttagg agctggtata aatcgtctaa
    17701 ggtgtcattt atgagatgag tcatcatatc atgtttatcc ctgtaatgca gataaaaggt
    17761 gcctctattg acaccagctt ttttggttaa gtcagaaacg gtaatggtct caaagctctt
    17821 ttctgtcaaa agactgacaa gtgcctgctt caaataggcc ttggttggtg tgtgtcttgt
    17881 tgtcatcgac tcatctcctt aagtcaacaa atgctgctta tctgttcttg ttaaagtctt
    17941 gaggacatta tataataagg ctagtataaa atcaacaagg tgttgatata aaggaggtga
    18001 catgatcagt gtcctatatt gaaatgaggt cctcttcaaa gacctaccag attggagaaa
    18061 caactgttaa ggctaatgat gaggtatcct ttgagattga aagaggggag cttgtgatca
    18121 ttttaggagc ctctggtgca ggcaagtcca cagtgcttaa tattttaggc ggcatggata
    18181 gcaatgacca aggtcaggtc ataatagacg gcaaggacat ctcgacctat agtaaaaagg
    18241 cattgaccag ctaccgtcgt tacgaggttg gctttgtttt tcaattttac aatctggtgc
    18301 caaatctgac agcaaaggaa aatgttgagc tggcggctga tattgtggca gatgcacttg
    18361 atccgactac tgtcttaaat gaggtggggc taggaggacg tttggagcat ttcccagcac
    18421 agctatcagg aggtgagcag caaagggtgt ctattgctcg tgccttggct aaaaatccta
    18481 agttgttgct ttgtgatgag ccaacagggg ctttagatta tcaaaccggc aagcaaattt
    18541 taagattgct tcaagatatg gcgcacgaca agggcaggac agttattgtg gtgacgcata
    18601 atactgctct agcgcctatt gctgatcggg tcatttatat gcatgacggt cgtgtgacca
    18661 agacagtgct taataagcag ccgcttgata ttgataggat aacgtattga gaggtgccta
    18721 gatgaaacaa aaaaccttat ggaaggatag ttttcgagca ataaaagcta gtaaggggcg
    18781 ttttttgtcc ttgctatttt taatggctct aggctccttt gccttggttg gcttaaaggt
    18841 ggctggtccc aatatggaaa aaactgctag tcactatcta gaggagcatc aggttatgga
    18901 ccttagtatc ctagcctcgc atggcttttc tgatagagat aagcaagaat tagcctctct
    18961 taaaaatgca agactagagt atgcgagctt tgttgatggt gcttttgatc accagaggaa
    19021 ggctattagg ctttattcta tgccacaaag cctatctcag gccagcttgg tcaagggaga
    19081 ttaccctagc aaggctagcg acattttgct atctgaagct ttatcaagcc gctatcggct
    19141 tgggcaaata atcacgataa gcctaaaaac aaagggattg ctaaagcata gatcctatcg
    19201 tgttgtcggc tttgctcatt ctccagaaat atggtccaaa acaaacttag gtgtttcctc
    19261 agcaggggat ggtaatctct atgcctatgc ctaccttcac cctagtgcct ttcagcaagg
    19321 gcacaatctc ttacgcattc ggtatgatga tttaagaggg ttgaatgcct tttcaactca
    19381 atacaatgaa cgattgctac aacaccaagc agagcttgat cagatcttgc aggacaatgg
    19441 tcaagagcgt tatgaagaaa tgctcaatga ccttaatcgc agcttgaaag atagtaaagt
    19501 taagctcgaa gagcaaagga ctgttcttaa ggcaagtgaa gaccagctgg ctttgctaag
    19561 tggtcatgcc ttagagcaag cgcagactca gctaaagcaa gggcaggaag agttagctaa
    19621 aaaagaagca agcttgctag agttagctga aaagcaaagg gcagcgatga tcaagccaac
    19681 ctatactagc tatagtcgct caacgctgcc aggtggtgag ggttatcaaa cctatgccac
    19741 ctcaacacag tccatatcgc atgttggaaa tatctttcct gttgttttgt atttggttgc
    19801 ggccttagtt acttttacaa caatggctcg ctatgttgac gaagaacgaa cgaactcagg
    19861 cttactaaag gcaataggct attctgattg ggatattacc aaaaaatttc tgctatatgg
    19921 tgccttagct gccttgttgg gcactggatt aggagtttta ggagggactt attttttatc
    19981 tcggctcatc tcagctatcc taacagatgc attgactatc ggctctactc agctttattt
    20041 ttattggagc tatagtgtgg ttgcagtgct tttagccttg ttatctgctg ttttgacagc
    20101 ttatatggtg gtgagacgtg agctttttct cagaccctca caactgttgc tgcctaagcc
    20161 tcctagtagc ggggcaagga tttggctgga gcatgtctcc tttatctggc ggcgtttatc
    20221 ctttacctat aaggttactt ttcgaaatat ctttcgatat aagcaaagaa tgctgatgac
    20281 agtaattgga gtagcaggtt ctgttgcgct cttattttcc ggcttgggca ttcaatcctc
    20341 acttgctaat agcctaagct atcaatttgg caagctgaca gcctatgaca tgctcgtggt
    20401 agaagctcca acagcagaag ctcatgatag gcaggagctg gcacaatatt tgaaggcaga
    20461 tcagattgct agtaagaaag agatttatta cgctaactta tcactaaaga taaaagactt
    20521 agacaacaag caaacagtgt cgttgatttc tagcgatcag agcactctat ctccctattt
    20581 tagcttgatt ggtgctgctg accgaaaaaa gctagacctt ccaagtactg gagtgcttat
    20641 ctcaaaaaag cttgctgact attatcaggc tcatgcagga gatcagcttg agcttgaagc
    20701 tagtaacggt aaacgctatc agttaagagt gagtcaggtt attgacatga ctgttggtca
    20761 ttacttgttc atgtctaaat cttattatca gcaggtattt cgggatatgg aggcttcacc
    20821 atcctatttg gtaacaacag caaaggctag tccatctgct gtaaaggacg tagctagtca
    20881 gctcttagca atgcctgcgg ttcaggctgt gtcacaacac agtagtattg ttgctactgt
    20941 gacagggatt gtggcgtctt tggatcaggt tatgacgctt ttagtacttc tatcagttct
    21001 actagccttg gtcattttgt atcatttgac caatatcaat attgctgaga gggttaggga
    21061 attatcaacg ataagagtct tgggctttta tgacaaggag gttaccttat acatttaccg
    21121 ggaaaccatg cttttgtctg ctgttggtat tttgatcggt ctctggggtg gcagctattt
    21181 gcacgcctat atcatgaagg tgattgctaa tgattctatg agctttggta ggacagttga
    21241 tgcttatgtt tacctagtac ctgttggggc tattgtgctt ttgttgattg tgcttggcta
    21301 tatggttagc taccggctaa gaaagattga tatgctagag gctctaaagt ctgttgatta
    21361 gggtaaaata gtacttgaaa atcgcttaat aatatgctag tattaaaata ctataattta
    21421 atagaaggat acttttatgg aagcgatgat agctgcctat ttggctgatc atagagaaaa
    21481 gataccactt ggtcaggttg ttgattgctt taaggggaag gctgtttctc gtaaggctga
    21541 ggctggtgaa tttggtttga ttaatctgtc tgatatggga cagctaggaa ttgactatca
    21601 tcaggttaga gcctttcata tggatagacg acaactattg cgctatatct tagaggatgg
    21661 agatgtcttg attgcctcaa aggggactgt tcagaaggtt tgtgtttttc ataagcaaga
    21721 aagggaaatg gtagcgtcct ctaatatcac agtgctgcgt cctcagaggg ttttgcgagg
    21781 ctattatatt aagttctttt tggagtctgc tattggtcaa gccttgttaa aggcggcgga
    21841 tcatggaaag gacgtgatta acctatcgac caaggcttta cttgatatcc ctgtaccagt
    21901 gattcctttg gttaagcagg attatttgat taatcaatat ttgcgaggcc tgcatgacta
    21961 tcaacggaaa gtaaacagag ctgagcagga gtggcagttt attcaaaatg aaattcaaaa
    22021 aggcttgggc tagaggtaaa atgtgagctt aattgaacga acaataaaaa tgctattagc
    22081 aacgatggct gcaatctttc ttgcctctca gctacagctg tcttatgcca tatcagcggg
    22141 aattattgcc ctgttaggtg tgctagacac tagaaaatct agcttaattg ttgctagaaa
    22201 gcgtctgctg tcttttttct tagcctttgc tgtggcggtt agtctatttg ccttatttgg
    22261 ctttggtctg ctttccattg gcttgtatct agcgctaacc attcctttgc tttatcagct
    22321 gaaaatagag gcaggtcttg ttcctatcac tgtcttggtg actcacctga tgtctgagca
    22381 gcgtattgat ttgtcaattc tttttaatga gctgttgctg tttttgattg ggacgggtct
    22441 tgcccttctt gttaacgggt atatggggtc tcaggagcat cgcctacgct tgtaccacca
    22501 aaagatagaa gatagcttaa aggctatctt gtaccgtttt gaatcctttt tgttagaagg
    22561 ccaaggacaa aacgagggac agatgattaa ggaattagag cttagcttag atgaggcgct
    22621 aaagctggtt tatcgcgaaa ggcacaatac cctcttttat cataccaatt atcaggtgca
    22681 ttattttgag atgagacgtc atcaaaatag attgttggcg caaatggcct taaatgtcac
    22741 tcagctaaca tctcaaagca gagaaagtct cctgctctcc catctttttc atgagacagc
    22801 tcgtcagctg agtgagaaga attctgcttt gacattgatt gatgatattg agcaattgct
    22861 tgaggtcttt aggcaaagag agctgcctca gactagagag gaatttgaaa gacgggcgat
    22921 tctgtttcag ctgttgcagg atttggagcg ctttattcta ctgaaggtag aattttatcg
    22981 tgattacaag gaagagcagg catagtagct gcttgctgct gtgattaaga gtctggaaaa
    23041 atcattttct aggctttt
//
LOCUS       DARYVE010000028        22707 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYVE010000028 DARYVE010000000
VERSION     DARYVE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22707
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            514..1998
                     /locus_tag="TVW25_001058"
     CDS             514..1998
                     /locus_tag="TVW25_001058"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1378697.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            2038..3339
                     /locus_tag="TVW25_001059"
     CDS             2038..3339
                     /locus_tag="TVW25_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1378698.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            3719..4027
                     /gene="rpsJ"
                     /locus_tag="TVW25_001060"
     CDS             3719..4027
                     /gene="rpsJ"
                     /locus_tag="TVW25_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1378699.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHNYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4325..4951
                     /gene="rplC"
                     /locus_tag="TVW25_001061"
     CDS             4325..4951
                     /gene="rplC"
                     /locus_tag="TVW25_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1378700.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            4976..5599
                     /gene="rplD"
                     /locus_tag="TVW25_001062"
     CDS             4976..5599
                     /gene="rplD"
                     /locus_tag="TVW25_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1378701.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            5599..5895
                     /locus_tag="TVW25_001063"
     CDS             5599..5895
                     /locus_tag="TVW25_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1378702.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            5913..6746
                     /gene="rplB"
                     /locus_tag="TVW25_001064"
     CDS             5913..6746
                     /gene="rplB"
                     /locus_tag="TVW25_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1378703.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            6858..7136
                     /gene="rpsS"
                     /locus_tag="TVW25_001065"
     CDS             6858..7136
                     /gene="rpsS"
                     /locus_tag="TVW25_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1378704.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7152..7496
                     /gene="rplV"
                     /locus_tag="TVW25_001066"
     CDS             7152..7496
                     /gene="rplV"
                     /locus_tag="TVW25_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1378705.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7509..8162
                     /gene="rpsC"
                     /locus_tag="TVW25_001067"
     CDS             7509..8162
                     /gene="rpsC"
                     /locus_tag="TVW25_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1378706.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8166..8579
                     /gene="rplP"
                     /locus_tag="TVW25_001068"
     CDS             8166..8579
                     /gene="rplP"
                     /locus_tag="TVW25_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1378707.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            8589..8795
                     /locus_tag="TVW25_001069"
     CDS             8589..8795
                     /locus_tag="TVW25_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1378708.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            8820..9083
                     /gene="rpsQ"
                     /locus_tag="TVW25_001070"
     CDS             8820..9083
                     /gene="rpsQ"
                     /locus_tag="TVW25_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1378709.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9108..9476
                     /gene="rplN"
                     /locus_tag="TVW25_001071"
     CDS             9108..9476
                     /gene="rplN"
                     /locus_tag="TVW25_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1378710.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            9560..9865
                     /gene="rplX"
                     /locus_tag="TVW25_001072"
     CDS             9560..9865
                     /gene="rplX"
                     /locus_tag="TVW25_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1378711.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9889..10431
                     /gene="rplE"
                     /locus_tag="TVW25_001073"
     CDS             9889..10431
                     /gene="rplE"
                     /locus_tag="TVW25_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1378712.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10447..10632
                     /locus_tag="TVW25_001074"
     CDS             10447..10632
                     /locus_tag="TVW25_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1378713.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            10965..11363
                     /gene="rpsH"
                     /locus_tag="TVW25_001075"
     CDS             10965..11363
                     /gene="rpsH"
                     /locus_tag="TVW25_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1378714.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            11685..12221
                     /gene="rplF"
                     /locus_tag="TVW25_001076"
     CDS             11685..12221
                     /gene="rplF"
                     /locus_tag="TVW25_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1378715.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12324..12680
                     /gene="rplR"
                     /locus_tag="TVW25_001077"
     CDS             12324..12680
                     /gene="rplR"
                     /locus_tag="TVW25_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1378716.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            12699..13193
                     /gene="rpsE"
                     /locus_tag="TVW25_001078"
     CDS             12699..13193
                     /gene="rpsE"
                     /locus_tag="TVW25_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1378717.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13208..13390
                     /gene="rpmD"
                     /locus_tag="TVW25_001079"
     CDS             13208..13390
                     /gene="rpmD"
                     /locus_tag="TVW25_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1378718.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            13592..14032
                     /gene="rplO"
                     /locus_tag="TVW25_001080"
     CDS             13592..14032
                     /gene="rplO"
                     /locus_tag="TVW25_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1378719.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            14049..15353
                     /gene="secY"
                     /locus_tag="TVW25_001081"
     CDS             14049..15353
                     /gene="secY"
                     /locus_tag="TVW25_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1378720.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            15505..16146
                     /locus_tag="TVW25_001082"
     CDS             15505..16146
                     /locus_tag="TVW25_001082"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1378721.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16264..16482
                     /gene="infA"
                     /locus_tag="TVW25_001083"
     CDS             16264..16482
                     /gene="infA"
                     /locus_tag="TVW25_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1378722.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            16508..16624
                     /gene="rpmJ"
                     /locus_tag="TVW25_001084"
     CDS             16508..16624
                     /gene="rpmJ"
                     /locus_tag="TVW25_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1378723.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            16642..17007
                     /gene="rpsM"
                     /locus_tag="TVW25_001085"
     CDS             16642..17007
                     /gene="rpsM"
                     /locus_tag="TVW25_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1378724.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            17025..17408
                     /gene="rpsK"
                     /locus_tag="TVW25_001086"
     CDS             17025..17408
                     /gene="rpsK"
                     /locus_tag="TVW25_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1378725.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17455..18393
                     /locus_tag="TVW25_001087"
     CDS             17455..18393
                     /locus_tag="TVW25_001087"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1378726.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSVRVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18408..18794
                     /gene="rplQ"
                     /locus_tag="TVW25_001088"
     CDS             18408..18794
                     /gene="rplQ"
                     /locus_tag="TVW25_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1378727.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(19012..19243)
                     /locus_tag="TVW25_001089"
                     /pseudo
     CDS             complement(19012..19243)
                     /locus_tag="TVW25_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20099..21349
                     /locus_tag="TVW25_001090"
     CDS             20099..21349
                     /locus_tag="TVW25_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378728.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            21339..22214
                     /locus_tag="TVW25_001091"
                     /pseudo
     CDS             21339..22214
                     /locus_tag="TVW25_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22235..22528
                     /locus_tag="TVW25_001092"
     CDS             22235..22528
                     /locus_tag="TVW25_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1378729.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         6997 a         4074 c         5037 g         6599 t
ORIGIN      
        1 gattgcatga agtataatgc ctataagttt ttagtactca attttatgat ttaatattta
       61 aattaagcaa tagtcaagtc acctttcact aagaaaaatc acttgattat tgcttagttt
      121 tttctaatgg aggattttta gtttagaagc tttgagttta gacctcaaaa cttagatatg
      181 gaattcgaaa ggcagtcact gctgtcaaca ttactttggg aaagttccta taagagactt
      241 ttcattagac tgaagtagct tcaatagctc taaaactacc tagactcaag taacaacaag
      301 tccttagaat tgattttcta agggcttttt tgctgcctca aggtaaagac atgttcagca
      361 acaaattgac tggctagacc agtcctttat ttatgctgat ggcttgagac tgctgggtta
      421 ttagcacaga aaatggctgt ctccaaatcc tagaaggctt atgattggaa tatgatataa
      481 tagtcaaaag aaatgatgag gtgatgtgaa gcaatgccaa tgatgtacca atcaacaaga
      541 aatgcagcta ataaggtaac agctagtcaa gcgattttaa gtggcctagc agatgatggt
      601 ggcttgttta ctcctacaag catgccagtg ctggatctag attttgagga gctaaagacc
      661 aagtcctatc aagaggttgc caagcttatt ttatcagcct tttttgatga ctatactgaa
      721 gcagaattag atgcttgtat ctcttctgcc tatgatgata agtttgatac agcagtgata
      781 gcacctctag ctacgttaaa ggattatcat aatttggagc tatttcatgg ctcaaccatc
      841 gcatttaagg acatggctct atctattttg ccttatctct tgacaactgc tgctaaaaag
      901 caaggtgtgg agcgaaaaat tgcgatttta accgctacct caggtgatac tggtaaggca
      961 gcaatggcag gctttgttga tgttccggga acggatatta ttgtctttta tcctaagtca
     1021 ggcgttagca ggattcagga gctgcagatg atcacacagg ccggtcacaa tacccatgtt
     1081 gtggcgattg aaggcaattt tgatgatgct caaacagagg tcaagcgcct gtttaatgac
     1141 cctgatttgc gtgagcggct agcagctcaa cagatacagc tgtcttcggc caattcgatg
     1201 aatattggtc gtttgattcc tcaggttgtc tattatattt atgcttatgc ccagttggta
     1261 aggcatcagc gacttgaagc tggagagacg attaacatag tagtgccgac aggaaatttt
     1321 ggcaatctac tggttgccta ctacgccaaa gaaattggac ttcctgttgc caaattcatc
     1381 tgtgcttcca atgaaaacaa tgtcttgaca gatttctttg ctagtggtag gtatgataaa
     1441 aagcgtccct tcaaggtgac tactagtcca tcaatggata ttttggtgtc ttcaaattta
     1501 gagcgcttgg ttttttattt actaggcaat gatgcccaaa agacagcagt attaatgaag
     1561 agcttggcag aaacaggtca gtatcagcta gctgatgcag atcagtctat ccttgattta
     1621 tttgcggcag gctttgcaac agagcaagag actgctaaag agatcaaaac gatatttgag
     1681 tctgatcatt atgtgcttga cccacataca gctgtagctt cagctgttta tcgtgcttat
     1741 cgggagcaat caggtgactc tagaccgact attgttgcgt caactgctag tccttataag
     1801 tttccgcggg tagttgtgga agctattagt ggtcagcagg ttgccagtga ttttgaggcg
     1861 cttgagcagt tggctgatat atcaggtgta gtcgtgccac aagcggtcaa tggcttacag
     1921 gaggcgccca ttcgtcatag ccttttagtg acagtagcag atatgcagca ggcagtagag
     1981 gcttatcttg gagtatagga ggcataaagg agctcccttt caattgatat gaatataatg
     2041 actcacaata gaaaaaagat actgtccttg gcccttccat caatggcaga aaatatattg
     2101 caaatgctga tgggaatgat agacaattat ttggctgctc aaattggact tacggctgtt
     2161 tcaggcattg cgattgctaa taatattctg acgatttatc aggccctttt tatcgcatta
     2221 ggtgctgcag tctccagtct cattgctaga agcgtaggag agcaaaacca ttctaaagaa
     2281 atcgactaca tggcaaatgc tatcttagta acgggggctc tatcagttct tctaggcttg
     2341 atgtccgtag tgggacataa aagcatatta gcctttctgg gagcagctag tctggtagct
     2401 agacttggtg ggcagtattt agccattgtc ggtggaatga ttcttagtct tggtcttttc
     2461 acgagcttag gtgcgattat tcgtgctaag ggccagccta gcattcccat gaaggtcagc
     2521 cttttaacta atttgctaaa cgctgtattt tcagcccttt ctctttacat atggggattt
     2581 ggagtgatag ggattgcttg gtcaactgtt gcatcacgtc tcattggagt tgttattcta
     2641 tgtcactttc ttcctattaa agaaattatt aaacgttttg ctaatccctt agataaagag
     2701 atctttagcc tctctcttcc agcggctggt gagcggctca tgatgcgagc tggtgatgtg
     2761 ctgattgtta ctattattgt tagatttgga acagaggcct tggcaggcaa tgcgattgga
     2821 gaaaccttaa ctcaatttaa ttatatgccg ggacttgcta tgtcaactgc gacagtcatt
     2881 ttagttgcca atcagttggg cagtggcaaa ggggctacaa tagcgaaaac tgtaaaagaa
     2941 acctttttgt tagccaccct gatgatgctt gttatgggct tgatcactta tttgctaggc
     3001 cctaatctac tgcccttatt tacagcagat gccaaggctc agcaggctgg tatggttgtc
     3061 ttagtctttt ctcttttggg ggtaccagca acagccggga ccttggttta tacagcagcc
     3121 tggcagggta tcggacaagc taagcttccc ttttatgcaa caacgattgg tatgtggctg
     3181 gttcggattt ctttgggcta ctttattgga gtaaccttaa attatggagt aataggtgtt
     3241 tggcttgcga ctattttgga caatgctacc agatggctca ttcttgcagt ggcttttaag
     3301 aagcagcaaa ggcagctttt ttcggactgt catagctaaa ctttgtattt aggtctcaag
     3361 acttctgagt ggtgactttc cttttgggag tcagccactg tcatcagaat gtaaagtacg
     3421 cctgaggctc tgtttgctaa tagcttctct tatctgcgga agatcaaaga ggattgctgg
     3481 aacagctgag gtttgtcttc aatctggctt gccctttctt agggcaagtt tttttgaaaa
     3541 aatcccctga aaggcttgca atgccttatt aattctgcta ttatattatg gtgctgtaaa
     3601 aatacagctt tagctgtgat acgagaggtt gcgacacgct cggttgcatt gccacgtgac
     3661 aggtgtcggt tttctcgagg agctagccta ttatcgtaaa tagacgagag gagaaaagat
     3721 ggcaaacaaa aaaatccgta tccgcttgaa agcgtacgaa caccgtacac ttgatacagc
     3781 ggcagaaaaa atcgttgaaa ctgcaactcg tacaggtgca acagtagctg gaccagttcc
     3841 acttccaact gaacgtagtc tttacaccat tattcgtgcg actcacaatt ataaagattc
     3901 tcgcgaacaa tttgaaatgc gtacacacaa acgtcttatt gatattgtga acccaacgca
     3961 aaagactgtt gatgcactta tgaaattgga ccttccaagt ggtgtcaacg tagaaatcaa
     4021 gctttaattg tttgaaacat gagtgaggaa cgagttcata tctaattgaa cacaggctaa
     4081 actctgtgtg aaaaagagac acagccgttc taattttaat tagattacgg atgtggctac
     4141 ctgtaggtgt aaatcttcct agaaacagaa gtttcttcgt cagatttcct attttcactg
     4201 tgagtttgac gccttaagta tcttgctttg agcataaaaa acgctcgtaa aaaacttttt
     4261 tgagcataaa aaacgctcac taaaaacttt ttgaaatatt attaagaaaa ggaattattt
     4321 tctcatgaca aaaggaatct taggggaaaa agtgggaatg actcaaatct tcactgaatc
     4381 cggtgaattt atccctgtta ctgtcatcga agcaactcca aacgttgtgc ttcaagttaa
     4441 gactgttgaa acagacggtt acgaagcaat tcaagttggt tttgatgata aacgtgaagt
     4501 attgagcaac aaacctgcca aaggccatgt agcaaaagct aacacagctc ctaagcgctt
     4561 cattcgtgaa ttcaaaaaca ttgaaggctt agaagtaggt gcagaaatca ctgtggatat
     4621 cttcgcagct ggggatgttg ttgatgtaac tggtacttca aaaggtaaag gcttccaagg
     4681 tgttatcaaa cgccatggtc aatcacgtgg tccgatggcc catggttctc gttaccatcg
     4741 tcgtccaggt tctatgggac ctgtttcacc aaaccgcgtt ttcaaaaaca aacatttggc
     4801 aggacgcatg ggtggcaatc gtgtaactat tcaaaatctt gaaattgtac aagttatccc
     4861 agaaaagaac gttattctta ttaaaggtaa cgtaccaggt gctaagaaat ctcttatcac
     4921 catcaaatca gcagttaaag ctgctaaata ataagaaagg agaaaacagt taaaaatggc
     4981 aaacgtaaaa ctatttgacc aaactggtaa agaagttagc acagttgaat taaatgatga
     5041 tatctttggt atcgaaccaa acgaatcagt tgtttttgat gttgtaatca gccaacgtgc
     5101 tagccttcgc caaggtactc atgcggttaa aaaccgttca gcagtatcag gtggtggacg
     5161 taaaccttgg cgtcaaaaag gaactggacg tgctcgtcaa ggttctatcc gctcaccaca
     5221 atggcgtggt ggtggtgttg tctttggacc aactccacgt tcatatggat acaaacttcc
     5281 acaaaaagtt cgtcgccttg ctttgaaatc agtttactca gcaaaagttg ctgaagataa
     5341 atttgtagct gtagaaagcc tttcatttgc agcaccaaaa acagctgaat ttgcaaaggt
     5401 gctttcagct cttagcattg atacaaaagt acttgttctt gttgaagaag gaaatgaatt
     5461 tgcagcactt tctgcacgta accttccaaa cgtagctgtg gcaacagcag cgactgcaag
     5521 tgttcttgat atcgtaaacg cagacaaact tcttgtaacg aaagaagcaa tctctacaat
     5581 tgaggaggtt cttgcataat gaatttgtac gacgtaatca aaaaaccagt tattactgaa
     5641 aaatcaatgt atgcccttga agaaggtaaa tacacatttg aagttgacac acgtgcgcac
     5701 aaactgttaa tcaagcaagc tgttgaagct gcatttgacg gagttaaggt tgcaagcgtc
     5761 aatactgtta acgttaaacc aaaggctaag cgtgttggtc gttacacagg ttttacttca
     5821 aaaactaaaa aggctatcat cactcttaca gctgattcta aagcaatcga gttgttcgca
     5881 gttgaagctg aataatctaa ggaggaaata acgtgggtat taaagtttat aaaccaacga
     5941 caaatggccg tcgtaacatg acttctttgg atttcgctga aatcacaaca agcacacctg
     6001 agaaatcatt gcttgtttct cttaaaaaca aagctggtcg taacaacaat ggtcgcatta
     6061 cagttcgtca ccaaggtggt ggacacaaac gccattaccg tttgattgac ttcaagcgta
     6121 acaaagatgg tgttgaagca gttgttaaaa caatcgaata cgatccaaac cgtactgcaa
     6181 acattgcact tgtacattac actgacggag ttaaggctta catcatcgct cctaagggtc
     6241 ttgaagtagg tcaacgtatt gtttctggac cagatgcaga tattaaggtt ggtaatgcac
     6301 ttccattagt aaacattcct gttggtacag ttgttcacaa cattgagctt aagcctggta
     6361 agggtggaga gcttgtacgt gctgctggag cttctgctca agtacttggt caagaaggca
     6421 aatacgttct tgttcgtctt caatcaggtg aagttcgtat gattcttgga acatgtcgtg
     6481 caactgttgg tacagttggt aacgagcaac aatcacttgt taacattggt aaagcaggac
     6541 gtagccgttg gaaaggtatc cgcccaacag ttcgtggttc tgtaatgaac cctaacgatc
     6601 acccacatgg tggtggtgaa ggtaaagcac cagttggacg taaagcgcca tctactcctt
     6661 ggggtaaacc agcgcttggt cttaaaacac gtaacaaaaa agctaaatct aacaagcttc
     6721 ttgttcgtcg tcgtaacgaa aaataagcgg caaatctagc ataagcttat tcaatcattc
     6781 cgccagctcg gtagagtttg agcttgctct catgctcaag ccgctgtggt acattattta
     6841 aaggagaaaa ctacaaaatg ggacgtagtc ttaaaaaagg acctttcgtc gatgagcatt
     6901 tgatgaaaaa agttgaagct caagctaatg acgaaaagaa aaaagtaatc aaaacttggt
     6961 cacgtcgttc aacgattttc ccaagtttca tcggatatac aatcgcagtt tatgatggcc
     7021 gcaagcatgt acctgtgtac attcaagaag acatggtagg tcacaagctt ggtgaatttg
     7081 caccaactcg tacctacaag ggtcacgcag ctgacgacaa gaaaacacgt cgttaatagg
     7141 aggaggacac aatggcagaa attacttcag ctaaagcaat ggctcgtaca gtgcgtgttt
     7201 cacctcgtaa aacacgttta gtacttgatc ttatccgcgg taagaaagtt gctgatgcaa
     7261 tcgcaatctt aaaattcact ccaaacaaag cagctcgtgt tattgagaaa actcttaact
     7321 cagcaattgc taacgcagaa aataactttg gtttggaaaa agctaacttg gtagtatctg
     7381 aaacatttgc aaacgaagga ccaacaatga aacgtttccg tccacgtgca aagggctcag
     7441 cgtcaccaat caacaagcga acaactcacg ttacagtagt tgtatcagaa aaataaggag
     7501 gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg tgtcggaatc attcgtgact
     7561 gggatgcaaa atggtatgct gaaaaagaat acgcggatta ccttcatgaa gatcttgcaa
     7621 tccgtaaatt cattaacaaa gaattggcag aggcttcagt ttcaacaatt gaaattgagc
     7681 gtgctgtaaa taaagttatt gtttcacttc acactgcaaa gcctggtatg gttatcggta
     7741 aaggtggagc aaatgttgac gctcttcgcg ctcagcttaa caaattaact ggaaaacaag
     7801 tacacatcaa catcatcgaa atcaaacagc ctgatcttga tgcccacctt gttggtgaaa
     7861 acattgctcg tcagcttgag caacgtgttg ctttccgtcg tgctcaaaaa caagctattc
     7921 aacgtacaat gcgtgctgga gctaagggaa tcaaaactca agtttcaggt cgcttgaacg
     7981 gtgcagatat cgcgcgtagc gaaggctact cagaaggaac tgttcctctt cacacacttc
     8041 gtgcagatat tgactatgct tgggaagaag cagatactac atacggtaaa cttggtgtta
     8101 aagtttggat ttatcgtggt gaagttcttc cagctcgcaa aaacactaaa ggaggcaaat
     8161 aacagatgtt agtacctaaa cgtgttaaac accgtcgtga gtttcgtgga aaaatgcgcg
     8221 gtgaagcaaa aggtggaaaa gaagtatcat tcggtgaata tggtcttcaa gctactacta
     8281 gctcatggat cactaaccgc caaatcgaag ctgctcgtat cgctatgact cgttacatga
     8341 agcgtggtgg taaagtttgg attaaaatct tccctcacaa atcttataca gctaaagcta
     8401 tcggggttcg tatgggttct ggtaagggtg cacctgaagg ttgggtagca ccagttaagc
     8461 gtggcaaggt tatgtttgag gttgctggtg tttctgaaga aatcgctcgt gaagcacttc
     8521 gtcttgctag ccacaagcta ccagttaaat gtaaattcgt aaaacgtgaa gcagaataag
     8581 gagaagacat gaaacttgaa gaaatcaaaa agtttgttgc tgagcttcgt ggcttgtctc
     8641 aagaagagct tgctaagaaa gaaaacgaac tcaaaaaaga acttttcgac cttcgttttc
     8701 aagctgcagc aggtcaacta gatcaaactg ctcgtttgaa cgaagttaaa aaacaaattg
     8761 cacgtgtaaa gactgtgcaa tctgaaatga aataatagat tgggaaagga gtattctaaa
     8821 taatggaacg taatcaacgt aaaacccttg ttggacgtgt tgtatctgac aagatggaca
     8881 aaacaatcac tgttatagtt gaaacaaagc gtaaccaccc agtctatggt aaacgtatca
     8941 actattctaa aaaatacaaa gcacatgacg aaaagaacct tgctaaagaa ggcgatatcg
     9001 ttcgtatcat ggaaactcgt ccactttcag ctacaaaacg cttccgtctt gtagaaatcg
     9061 tggaagaagc tgttattatc taatcaaact aaaaggagac aattgaaatg attcaacaag
     9121 aaactcgctt gaaagttgct gataatagcg gtgctcgtga gatcttgact atcaaggttc
     9181 ttggtggttc agggcgtaag tttgctaaca tcggtgacgt catcgttgca tctgtaaaac
     9241 aagctactcc tggtggagca gttaaaaagg gtgatgttgt taaggctgtt attgttcgta
     9301 caaagagtgg tgctcgtcgt ccagacggtt catacatcaa atttgatgac aatgcggctg
     9361 tcattattcg tgatgacaag actcctcgtg ggactcgtat ctttgggcct gttgcacgtg
     9421 aattgcgtga gggtggctac atgaagatcg tatcacttgc accagaagta ctttaatttt
     9481 aatcattaaa caaactaagt cccctaggct agcctagggt gcccataggg gcgtaagaaa
     9541 ataataggag aaacccataa tgtttgtaaa aaaaggcgac aaggttcgcg ttattgctgg
     9601 taaggacaaa ggtgttgaag ctgttgttct taaagcactt ccaaaagtaa acaaagttat
     9661 tgttgaaggc gtagccatca tcaaaaagca tcaaaaacca aacagcgaaa atcctcaagg
     9721 tgctatcgtt gaaaaagaag caccaatcca tgcatcaaac gttcaagttc ttgataaaaa
     9781 tggtgttgct ggacgcgttg gttacaagtt tgtagacggc aaaaaagttc gttacaacaa
     9841 aaaatcaggc gaagtgcttg attaatcacg aaggaaagga gaagcataat ggcaaatcgt
     9901 ttaaaagaaa aatatactaa cgaagtaatt cctgcgttga cagagaagtt taattacaca
     9961 tcagttatgg ctgtgccaaa ggttgagaaa atcgttctta acatgggtgt gggtgacgct
    10021 gtatcaaacg ctaaaaacct tgaaaaagct gctgcagaat tggcgcttat ctcaggtcaa
    10081 aaaccactta ttactaaagc taagaaatca atcgctggct tccgtcttcg tgaaggtgtt
    10141 gctatcggtg cgaaggtgac acttcgtggc gaacgcatgt acgaattcct agacaagcta
    10201 gttagcgttt cacttcctcg tgttcgtgac ttccatggtg ttccaacaaa atcatttgat
    10261 ggtcgtggta actacactct tggtgtgaaa gaacagctta tcttcccaga aatcaacttt
    10321 gatgatgttg ataaagtgcg tggtcttgat attgttatcg taacaactgc taacactgac
    10381 gaagaatcac gtgaattgct taaaggtctt ggaatgcctt ttgcaaaata atagggggta
    10441 actaaattgg ctaaaaaatc tatgattgct aaaaacaaac gtcctgcgaa gtattctaca
    10501 caagcttaca ctcgttgtga aaaatgtgga cgtccacatt ctgtttaccg caagtttaag
    10561 ctttgccgcg tttgcttccg cgagttggct tacaaaggcc aaatcccagg tgttgttaaa
    10621 gcgtcttggt aaaatgatga tgtgagagcg ttaagctacc taagcaaaaa taggaaaatt
    10681 gacgaagagt ctaaatactc taggaaattt tgcacctaaa ggtagtagct tgaactcagt
    10741 tcaaatgaac aaataatact atcagatatt atgtctgatt cgatgcaaag gcaaagtgtc
    10801 aatttgaaca cgggcgaaag ccggtgtcaa aaagataaac attccttgga ggttttccct
    10861 cctgcggaag tttcctattt tgactttggc ttttagcgcc ctttgtatca tcgattaact
    10921 agcaagtgca gcttgcaaac tactagtaag aggagaataa taaaatggtt atgactgacc
    10981 caattgcaga ctttttgaca cgtattcgta atgctaatca agtaaagcat gaagtgttag
    11041 aagtacctgc atcaaatatt aaaaaaggga ttgcagaaat ccttaagcgt gaaggcttta
    11101 tcaaaaacgt tgaagttatt gaagatggca aacaaggaat tattcgcgta tttcttaagt
    11161 acggtcaaaa tggtgaacgt gtcatcacta acttaaaacg tgtttcaaaa ccaggtcttc
    11221 gtatttattc taagcgtgag gatgttccaa aggttcttaa tggactagga attgcaatta
    11281 tttcaacttc agaaggtctt ttgactgata aagaagctcg tcaaaagaac gttggtggag
    11341 aagttatcgc atacgtttgg taatttaaga gacaaaagcc gtaacgaaca atctaaaatt
    11401 agaaaattat tgtggcttgc ttgcaaacaa aatagtttgt ctattttaga tggcagttcg
    11461 tcggctgtgc tcaaatgatg aacactatca acatagcaaa cgtaaaagaa ctaattgaac
    11521 atgggctaaa gtctgtgtga aaaagataaa tttttctaga aaccttggtt tcatagtaat
    11581 gtttcctatt ttcactttgc cttttacgcc ctaagtatct tagttcaccc cgtgaaaact
    11641 cgtcgcgtaa gcggcctgat aatttaacag gagaaaaaat taatatgtca cgtattggta
    11701 ataaggttat tattatccct gcaggcgttg aaatcattaa caacgacaat gttgttactg
    11761 taaaggggcc taaaggagag ctcactcgtg agtttaacaa aaatattgaa atcaaagtcg
    11821 aaggaaacga aatgactctt gtacgtcctg acgactcaaa agaaatgaaa acaattcatg
    11881 gtacaactcg tgcaaacttg aataacatgg ttgttggagt ttcagaaggt ttcaaaaaag
    11941 agcttgaaat gaagggtgtc ggatatcgtg cacagcttca aggctctaag cttgttcttt
    12001 cagtaggtaa atctcaccaa gatgaggtgg aagctccaga agggattaca tttactgtag
    12061 ctaatccaac atcaatttca gttgagggta tcaacaaaga agttgttggt caaactgccg
    12121 cttacattcg tagcctacgt tcaccagagc cttacaaagg taaaggtatt cgttacgttg
    12181 gtgagtatgt acgccttaaa gaaggtaaaa caggtaaata atgttcttag tggaatatgg
    12241 cataggcttg cttatgtcat gctctacaag ctcaattgat aatttgtcgg aaagacaaac
    12301 ttaaatatta agaggtgaaa attgtgattt cgaaaccaga taaaaacaaa atccgccaaa
    12361 aacgccatcg tcgcgttcgc ggtaaactct ctggaactgc tgatcgccca cgtttgaacg
    12421 tattccgttc taatacaggc atctacgctc aagttattga tgacgtagcg ggtgtaacgc
    12481 tcgcaagtgc atcaactctt gataaagaag tttctaaagg aacaaaaact gaacaagctg
    12541 ttgtagtcgg caaacttgtt gctgaacgtg cggtggctaa aggtatttct gaagtggtgt
    12601 ttgaccgcgg tggatatctc tatcatggac gtgttaaagc tttggctgat gcagctcgtg
    12661 aaaacggatt gaaattctaa tagggaggac acaaaataat ggcatttaaa gataatgcag
    12721 ttgaacttga agaacgcgtt gttgctatta accgcgttac aaaagttgtt aaaggtggac
    12781 gtcgtcttcg ttttgcagct cttgtagttg ttggtgatgg aaacggacat gttggattcg
    12841 gtactggtaa agctcaggaa gtaccagaag ctattcgcaa ggcagttgaa gctgctaaaa
    12901 agagcatgat tgaagtgcca atggttggca caacaattcc tcacgaggtt tacactaact
    12961 ttggtggagc taaagtattg ttgaagccag ctgtagaagg ttctggagtt gctgctggtg
    13021 gtgcggtacg tgccgtcatc gaattagcag gtattgctga tattacttca aaatctcttg
    13081 gttcaaacac tccaatcaac atcgttcgtg caactgttga aggattaaaa cagcttaaac
    13141 gtgcagaaga agttgccgca cttcgtggca tctcagtttc tgacttagct taagaaaggg
    13201 gatcatcatg gctcaaatta aaattacttt gactaagtct ccaatcggac gtaagccaga
    13261 acaacgtaaa acggttgttg cccttggact tggtaaatta aactcttcag ttatcaagga
    13321 agataatgct gctattcgtg gtatggtgac agcaatttct cacttggtga cagttgaaga
    13381 tgtcaaataa agagttagct agaaatctct gatttcttgc attagcatgc agaaccggct
    13441 tttgtgagtt attcctttga atgacaagca gtggtcggtt ggtgcatata gcatcaggct
    13501 atgacatagc ttgatcatgt ataggcgagt ttctatggag agtcctttcc cttcatagag
    13561 gcgctagcat tttacaaaaa aaggagaaaa aatgaaactt catgaattga agcctgccaa
    13621 aggctctcgt aaagtccgca atcgtgttgg acgcggtact tcatcaggca atggtaaaac
    13681 atctggacgc ggtcaaaaag gtcaaaaggc tcgtagtggt ggtggcgtac gtctaggctt
    13741 tgaaggtgga caaacaccct tgttccgtcg tattccaaag cgtggattta caaatatcaa
    13801 cactaaagag tatgctcttg ttaaccttga tcaattaaac gcttttgaag atggcacaga
    13861 agtaactcca gttgttctta aggaagctgg aatcgttcgt gctgaaaagt caggcgttaa
    13921 aattcttggt aacggcgaat tgactaaaaa attgactgtt aaagcagcga aattttcaaa
    13981 atctgctgaa gcagccatta ctgctaaggg tggttcaata gaagtcatct aatgagggga
    14041 tactcattat gttcttaaaa atactcaaag acgcattgaa gataaagaat gttagaaata
    14101 aaatattttt tacaatcttt attatcctta tattccgtat tggaacacat atcactgttc
    14161 ctggtgtaaa tgcaaaaagc ttagagcagc tgagtgagct tcccttccta aatatgttga
    14221 acttggtcag cggtaatgca atgagaaact tttcagtttt ctcaatgggt gttagtccct
    14281 atattacagc ctcaatcgtt gttcagctat tgcagatgga tattttgccg aagtttgttg
    14341 agtggggaaa acaaggtgag gttggccgtc gtaagctaaa ccaagcgacg cgctatattt
    14401 cccttgtctt agcctttgct caatctatcg gtattacagc gggttttaac accttatcaa
    14461 gtgtggccct agtcaaaaca ccagatgtaa gaacctattt actgattgga gctttactga
    14521 caacaggtag tgtgattgtg acctggcttg gtgaacagat taccgataaa ggctttggta
    14581 atggggtgtc tatgattatc tttgcaggta tcatttcctc tattccaaat gctattgcaa
    14641 ccattcgtga ggattatttt gtcaatgtga agtcaggtga cctacagtca tcttatatcg
    14701 ttgttggtat tctcattctt gcagtgcttg ctatcgtctt tttcacaacg tatgttcagc
    14761 aggcggaata taaaattcca atccaatata caaagcttgt tcagggtgcg cctacaagct
    14821 cataccttcc cttaaaagta aatccagctg gtgttattcc cgttatcttt gccagctcga
    14881 ttacaacaat tccaagtacg attatcccgt tctttcaaaa tggcagagat attccatggt
    14941 tgacaacttt gcaaggaatt tttaactatc aatctccaac aggaatgatt gtttatgcct
    15001 tgttaattat cctgttttca ttcttctata cctttgttca agtaaatcct gagaaaacag
    15061 ctgaaaatct acagaagaat tcgtcctata ttccaagtgt tagacctgga cgagaaacag
    15121 aagaatttat gtcatccttg ctaaagaaat tggcaactgt gggtgctatc ttcctagcat
    15181 ttatatctct tgttccaatt gcggcacaac aagctcttaa cctatcttct agtattgcat
    15241 taggtggaac tagcttgctg attttgattt cgacaggtat cgaaggtatg aagcagcttg
    15301 aaggttacct tctcaagaga aaatatgtcg gatttatgaa tattacagaa tagaatatgg
    15361 gttgacactg tcaaccttct attttgtttt taaatgacaa taagatttac agagccttgg
    15421 ttcctatctt cttattgcca tttgaaaaca aaaacaagga aaactaaatt tcctattatc
    15481 tttatgtcaa aagaggagaa aaagatgaat cttttaatca tgggcttacc tggtgccggt
    15541 aagggtacac aggctgcaaa gattgttgaa acctttgagc ttattcatat ttcaacagga
    15601 gatatgttcc gcgctgcaat ggctaatcag actgaaatgg gagttcttgc gaaatcttat
    15661 atcgataagg gtgatttggt gccagatgag gtaaccaatg gtatcgttaa agaacgctta
    15721 gcacaagctg atattaaaga aaagggattt cttttagatg gctatcctcg taccattgag
    15781 caggcacatg ccttagatga aaccttaaaa gcattgggac ttacgttaga tggtgtgatc
    15841 aacattgagg ttgaccctgc gtcactcatt gacaggctta gcggtcgtat catcaacaaa
    15901 aaaacagggg aaaccttcca taagatcttt aacccaccag tgggagacta taaggaagag
    15961 gacttttatc aacgtgaaga tgataagcct gaaacagtta agcgtcgctt agatgttaat
    16021 attgcacaag gtgagcctat tatcaagcat tatcgtcaag caggcattgt tcgtgacatt
    16081 gacggaaaca aggacatttc tgaggtcttt gctgacataa aaaaggtcat cgaaaacctg
    16141 aaataaattc cagaaaatcg cttgcgaaag tgattttatc gtgatatact agactagtct
    16201 gacttataat tgttacctct gtgctcagag gacatcaaat cgaaatttag ggggtacttt
    16261 tgcgtggcaa aagaagacgt gattgaaatt gaaggtaaag ttgtcgaaac tatgccaaat
    16321 gcaatgttta ctgttgaatt ggaaaatgga catcagattt tagcaaccgt atcaggaaag
    16381 atccgcaaaa attacattcg tattttagtg ggtgatcgtg ttactgtaga gatgagtcct
    16441 tacgacttga cacgtggacg tatcacatac cgctttaaat agtcgaaata attggaggga
    16501 ttaaaacatg aaggtaagac catcggttaa accaatttgc gaatactgca aggttattcg
    16561 tcgtaacggt cgtgttatgg taatttgtcc gacaaatcca aaacacaagc aacgtcaagg
    16621 ataagataga aaggagaaaa aatggctcgt attgctggag ttgatattcc aaatgataag
    16681 cgtgtagtaa tttcacttac ctatgtgtat ggaattggtc ttgcaacatc taaaaaaatc
    16741 ttagcagcag caggtgtctc tgaggacatt cgtgttaaag atttgacatc agatcaagaa
    16801 gacgctatcc gtcgcgaagt ggatacaatt aaagttgaag gtgatcttcg tcgtgaagta
    16861 aacctaaata tcaagcgttt gatggaaatc ggttcatatc gtggaattcg tcaccgtcgt
    16921 ggacttcctg tacgtggaca aaacacaaaa aacaatgctc gtactcgtaa aggtaaagct
    16981 gttgcgattg caggtaagaa aaaataaaat aggaggtaaa aaaattggct aaaccaacac
    17041 gtaagcgtcg tgtgaaaaag aacatcgaat ctggtgttgc acatattcac gctacattta
    17101 ataacactat tgttatgatt acagatgtgc acggtaatgc tttagcatgg tcatcagccg
    17161 gtgctcttgg ttttaagggt tctcgtaagt caactccttt tgctgctcaa atggctgcag
    17221 aggctgctgc gaaatctgca caagaacatg gtttaaaaac tgttgaagtt actgtaaaag
    17281 gtcctggttc aggtcgtgaa tcagctattc gtgccctagc tgctgccggt cttgaagtaa
    17341 ctgccattcg tgatgtgact cctgtaccgc ataatggtgc tcgtcctcca aaacgtcgtc
    17401 gtgtataatc acagtaacaa atagtacaca agtttcgttt cgaggggtga aagaatgatt
    17461 gagtttgaaa aaccaataat aacaaaaatt gatgaaaata aagattacgg tagatttgta
    17521 atcgaaccac ttgaacgtgg atatggtaca actctaggta attcacttcg tcgtgtactc
    17581 ttgtcttcac ttccaggtgc agctgttaca tcaatcagaa ttgatggagt actacacgaa
    17641 tttgatacaa tcccaggtgt acgtgaagat gtcatgcaaa ttatccttaa tgttaaggga
    17701 cttgctgtga aatcatacgt cgaagacgaa aagattatcg agcttgatgt agaaggtcca
    17761 gcagaggtaa cagctggaga tattctcaca gatagcgata tcgaacttgt taaccctgat
    17821 cattatcttt ttactattgc tgatggttat acattgaagg cttcaatgac tgtcgctaaa
    17881 aaacgcggct atgtaccagc agagggtaat aaaaaagatg atgcacctgt ggggacgttg
    17941 gcagtagatt caatctatac gccagtaaaa aaggttaatt atcaagttga gcctgctcgt
    18001 gtaggtagta atgacggctt tgataaattg actattgaaa tcatgacaaa cggaacaatt
    18061 attcccgaag atgccttagg tttatctgtt cgagttttaa tcgaacactt gaatttattt
    18121 actgatttaa cagatgttgc aaaggcaact gaagtgatga aggaagctga aaaagtgaac
    18181 gatgaaaagg tacttgatcg cactattgag gaacttgatt tgtccgtacg ctcatataac
    18241 tgcttgaaac gtgccggtat taatactgtc ttcgatttaa cagaaaaatc tgagcctgaa
    18301 atgatgaagg tccgtaacct tggacgtaag agtcttgagg aagtaaaggt caagcttgct
    18361 gacttaggtt tgggactaaa aaacgataaa taacatagga ggataaaatg gcttaccgta
    18421 aactaggacg cactagctca caacgtaaag caatgcttcg tgacttaacg acagatcttt
    18481 tgattaacga atcaattgta acgacagaag cacgtgcaaa ggaaatccgt aaaacagttg
    18541 aaaaaatgat tactcttggt aaacgtggtg atcttcatgc tcgtcgccaa gcagctgcat
    18601 acgttcgtaa cgaaatcgca tcagaaaact atgatgaagc tactgataaa tacacatcaa
    18661 caacagctct tcaaaaactt ttctctgaaa ttgcgcctcg ttatgcagaa cgcaacggtg
    18721 gatacactcg tatccttaaa acagaaccac gccgcggaga tgctgctcca atggcgatta
    18781 ttgaattagt ttaattttta tcaattttgt tgagtgttat gatgatggag cagttccttt
    18841 aagctgttct tagtctagct ctggtctacc gctaggacct ttcctagcgg taacactcac
    18901 catgttgaga ataagtaacg cttgtttacg aaaggtctct aagctgtagg tgcccttcgt
    18961 aagcaggcgt tttgttgtga ctccatgtta actgtagtag atgactaata tctaatatct
    19021 agagaggatc agcttggtgc tctcttttct gatattaaaa gcattgggaa tcttggtttt
    19081 gaagttctta aagctcctaa agccaaagtc tttcgcttga tgtctttggt catcttgtta
    19141 gtggtctccg gcttagcatt ggaataaggt agttcaaagc attggtgatg taagatctat
    19201 acttcctgaa ggtcttgaaa accgttttga aggtgtgatt gacctgtagc gggagtagat
    19261 tagatcaatg gcgtttggct gctttgaaaa tttaggtgac aattgttttt gtatctttgt
    19321 ttaaaaatgg tataatatta aaacattaaa caaaatgtac ataaaaaagc catataaaag
    19381 aatgatatta agataatgtg atcaatagtt ttagaaaatg aatgtgtaag gttaaggtat
    19441 gcccccttga tataatgcta gttttacgaa gaggcattct gtacagacat aatgcactct
    19501 tacaaatgat acggtaattg ctcaacaagg cgcaacagcc ttggcaaatg taatatttgc
    19561 cttagctagc agcgaattag ttacgcttga tacatagaca agggtttctg gcatacagca
    19621 gcagatggtg tgcctgtctc agagagtggc tgcttggctt atcctattca tgttttaaaa
    19681 cttacaggag gtgttatgtg gcctttggtc gatggatatt tagctaggtg aacagctatt
    19741 agctgtaaat atgaggtagg agctttagtt tgcatgatgt taaatgaatt gaaacagact
    19801 taggaaagct tggcttagca actatcacgc aagttcttaa caacgataaa gatcgtatgg
    19861 gaaaatatga tcaagcatca acggacatga gatgtgtttt atgaagaaac cattatactt
    19921 ttataagact tatttagttg tttttctttg cggacttgtt tgaggagtag tctacatagg
    19981 caataggctc aggcttacag cacttaggag acattagagc atgagaagca ctaactggct
    20041 agtgatagaa aagtaatagc acagtgtttt tataactaac aagaggagta gacattctat
    20101 gagtattgac atgtatttga gcttatctga agagcaggca cagagtgtag aggctgtctt
    20161 agctaggcga caaacagcct atcaatcctt acaggagacc ttgatccaat tgatttctaa
    20221 cagtcctgat ttatcagggc ggacctatga ttctgctaag gcttatagta gtcaagtgct
    20281 aattcctttg ttaaaggggt gtatgctttt agatgaggcg attataacag cctgtaagag
    20341 gctacctagt gagtaccgta gtcaggtaga ccaaattgat ttgaaggaga gtgatctggt
    20401 tgagcgtatt gcccagttcg atcatgtgat tggtcggtac atggatttga ttagtattga
    20461 atacagtaga gaggagccta gctattctta tatctctcat ttaagatcag ctgagcagct
    20521 ccatcgggcc gttaagcggc gtcttgagga gatattgcga aggctaaggc attttgatac
    20581 caactcagtt cacctttttt cgactattca gactttggca gcagcggtac aaataggcat
    20641 gcgtcaagct aggacctcgt ggcatgcagg aagtcaggta tttgtgattt cagaggatat
    20701 ggcatgggcc gatacgatta attctaagtg gtcaaaaagt aaagggttaa gctatcttag
    20761 tgattatgtt tacgacccag atgtgctctc taagagagca gctattaatc actcttggat
    20821 taaaacaggc tatactatgt ctaaaaattt tggcaaagct gtttcaaaag attatacaaa
    20881 agcaagcttt ttgagctatg gtaaggcagc caaggcgact ggctggactt ctatggcagt
    20941 agatactgga ataactagtg taagggaata caataagaaa aatagtagag cctatggcag
    21001 tgagggcaag gcgcttattc atgctagtgt ggctcaaatc aagagcatgg gacctataga
    21061 aggggcgata attggcagta aagctggacc ttggggagca ttaatggggt ttgttacagg
    21121 aggcattaat gttacttggg gagtagtgca tccagagtct aaggacaaca tgtttttatg
    21181 gatacaagat aaaatggatg atgtttacga ttcgattgtt cagacagatc ttggcaaagg
    21241 gacgcaccat gctaaagaaa gtgtcaaagg tcatatcggt cgagctattg taaggacatg
    21301 ggactttgtc agtcaatcat ttggtaaagg agtgggctat gacatttaaa gatcagcttt
    21361 ttagtgggac gtttgagcaa tcaaaaaaga ttgtgtctaa aagtatattg acagaagaag
    21421 gtgcgcagat tggagtattc tcatctatga gtctatggaa gagaataaca ggcttgatga
    21481 tgttgccatt atttgctatt tcatatggag taggagttgt gttacctgaa cactttcaac
    21541 aatcaacaga aggagttcaa gctatttcat tggctgcaat agagattatt gccagattag
    21601 gacagttcag tcgatacttt atcatttgtt ttatttgtat gtctgttgga ttaattatta
    21661 gtaatatcct tccaaagcct aactaggctt atcaattatt atatggcaat gctactctta
    21721 ttatacttag tattacaact attatctcag ccttcccttt aactgctggc cttacaattg
    21781 cagcttttgg ctggatcggt tttttgcttc agctattgct ttgcctttat ttgtggaagg
    21841 tttgtgtcat agataagtgt caacagctac gcacagcaat ttatcaagaa agcaccatag
    21901 cacctgattg gggcagtaag ctagtaagct ttattaagtc ttatggtggt atcttattag
    21961 gcctctctgt tctcaaccgc tggactctca atctaggaga gctagtcaag gaaagccctg
    22021 gtttgttgag ttttctgtac ggctggattt ttctattgtt catgtttttg atgctatttg
    22081 cactgggtca agcgttaaaa aataccatca tagcctatta tttttttaga tatcaaaaag
    22141 aataccgcaa gcattttaat ataagcgatg agcagtggta cggtaaatgg cgtttaaaaa
    22201 tattattaaa ataaacgata taaggagtaa tcatatgcaa aaagaattat taccgttagg
    22261 aagtgttgtc tatctagagg gagcaacaag caagctaatg attgtcggac gtggtcctat
    22321 atttgaatct aatggccaaa atgtctacag tgattatgtt ggagtaatgt atccagaagg
    22381 gatcaatcca gaagacgcga tttttttcaa ccatgaagat attgcaaaaa cagtctttga
    22441 aggcttcaag gacgaagaag aacaacgctt tttagaagtg tattctgatt gggagagtac
    22501 tttagaaatt tccaaaataa agctatagat gaactgtagc agatatattt gtcagtagat
    22561 tgtcatgatt atattgaaag attatgactt tctctggctt aaatacctct aaagttccaa
    22621 agtttagaaa aggctttaaa atgagtgtta taatagcatt tatgctcatt aaataaaggt
    22681 agcatttcaa tagaatcggt aaaaaaa
//
LOCUS       DARYVE010000029        22388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYVE010000029 DARYVE010000000
VERSION     DARYVE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(67..489)
                     /locus_tag="TVW25_001093"
     CDS             complement(67..489)
                     /locus_tag="TVW25_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378730.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(812..1072)
                     /locus_tag="TVW25_001094"
     CDS             complement(812..1072)
                     /locus_tag="TVW25_001094"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378731.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(1087..2895)
                     /locus_tag="TVW25_001095"
     CDS             complement(1087..2895)
                     /locus_tag="TVW25_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378732.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(3536..4435)
                     /locus_tag="TVW25_001096"
     CDS             complement(3536..4435)
                     /locus_tag="TVW25_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1378733.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(4447..5256)
                     /locus_tag="TVW25_001097"
     CDS             complement(4447..5256)
                     /locus_tag="TVW25_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1378734.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(5240..5599)
                     /gene="rnpA"
                     /locus_tag="TVW25_001098"
     CDS             complement(5240..5599)
                     /gene="rnpA"
                     /locus_tag="TVW25_001098"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1378735.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(6091..6831)
                     /locus_tag="TVW25_001099"
     CDS             complement(6091..6831)
                     /locus_tag="TVW25_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1378736.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(6835..8133)
                     /locus_tag="TVW25_001100"
     CDS             complement(6835..8133)
                     /locus_tag="TVW25_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1378737.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(8145..9491)
                     /locus_tag="TVW25_001101"
     CDS             complement(8145..9491)
                     /locus_tag="TVW25_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1378738.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(9936..11381)
                     /locus_tag="TVW25_001102"
     CDS             complement(9936..11381)
                     /locus_tag="TVW25_001102"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1378739.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(11983..12696)
                     /locus_tag="TVW25_001103"
     CDS             complement(11983..12696)
                     /locus_tag="TVW25_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1378740.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(12824..13330)
                     /locus_tag="TVW25_001104"
     CDS             complement(12824..13330)
                     /locus_tag="TVW25_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1378741.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            13713..13991
                     /locus_tag="TVW25_001105"
     CDS             13713..13991
                     /locus_tag="TVW25_001105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378742.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(14152..15513)
                     /gene="radA"
                     /locus_tag="TVW25_001106"
     CDS             complement(14152..15513)
                     /gene="radA"
                     /locus_tag="TVW25_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1378743.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(15580..16026)
                     /locus_tag="TVW25_001107"
     CDS             complement(15580..16026)
                     /locus_tag="TVW25_001107"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1378744.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(16228..16995)
                     /locus_tag="TVW25_001108"
     CDS             complement(16228..16995)
                     /locus_tag="TVW25_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1378745.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(17157..18953)
                     /locus_tag="TVW25_001109"
     CDS             complement(17157..18953)
                     /locus_tag="TVW25_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378746.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISASKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(18953..20662)
                     /locus_tag="TVW25_001110"
     CDS             complement(18953..20662)
                     /locus_tag="TVW25_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378747.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(20655..21104)
                     /locus_tag="TVW25_001111"
     CDS             complement(20655..21104)
                     /locus_tag="TVW25_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1378748.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            21314..22333
                     /locus_tag="TVW25_001112"
     CDS             21314..22333
                     /locus_tag="TVW25_001112"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1378749.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         6662 a         5434 c         4207 g         6085 t
ORIGIN      
        1 gcaggctaat tattaagaac atgctttaaa atagcagagc taatctcggc tccgctatct
       61 taaacattat ttcaaaggac tgacataatc atctggcagt tttcccttcc aatctatcca
      121 tttttgctct gcgattggaa tcagttttct tagctcttct tgggtaaaaa gttcccaact
      181 tgttggatct gcaattaagg ctattgggga tctttgtaaa aatgctttat cactagctat
      241 tttctcttct tccgttggtg gccaacaatc atatcgcaat ttaaaagcaa tctcccctaa
      301 attccgtttt ccttgctcca ataattcaaa taaatcatac ggcagctcat atactactcg
      361 ctgctcagct ataccacctt cattagtcac tagatagtaa gttccctgac gcttccacac
      421 ctgttgacca taacccttga cttcctcata ttgactaaca tcttcccact ctaattgact
      481 atgttccatg tatgttctcc tttacttgta ctgatatctt tcataactcc ctctggcata
      541 tcacccggat aagtacgacc tccaggtcgc caccagctat tagcaccctt ttcattacca
      601 cttggaatag aaatcccttt ctccgaaaca acctctggtg aaacatctaa gcgatagagc
      661 ggatcattgc caagataacc ctcgtcgaag ccgagtaagc tttcataaaa gattgatgca
      721 tagtcagctt actcttgttc ctcctttctt cagtttttta tcataatttc atcttaaaat
      781 ttaatcaatt cgagcaatct aatctcactc atcatctcct tttcctattt aggcatactt
      841 ctaagtcctt caaagttttt aaaattggac tatcatactg tgttgtatca tcaacaaatt
      901 gtctagctaa acttgaaaaa ttaatattcc caacaatccg attattatca atatcattag
      961 tcaaaacata aagatctctt aatattcctg aatagttttt ttgcttggga tactcaagtt
     1021 ctattaactc tctaagcctt tgtgtatatt gaaaacagtt attattatcc ataaatttct
     1081 ccttttttag ttaggaacga tccttatttc ttgaatccac tccaatggcc accgattggg
     1141 aagtaagacc tgatctccac ctccaattaa ggttgttcct gaagatttaa ccgtctgtgg
     1201 ggcaaccttg ccaatattca attgactccc ctttggtatt ttaattacag cctcatattg
     1261 tctagtattt ttccattctg gaagtaaagc tgtatctatt tttgcttgta tacgattagt
     1321 tgcaggcacc gttgtgacaa aaccgcctcc agcatctgac gcccctccaa aagtcctata
     1381 aagtgttatt tcctcacctg taataactgt tctatagtga ctatctgtaa atgaatctgc
     1441 aatccaacca ggaagatttt ccttagcccc aactgttact ttactatcta tttgagttgg
     1501 atattttgta acactttctt tttttatata gcctccgaaa ttagaactct ctctcgccag
     1561 cctgctgttc tcaaggttct tcaaaagctg ctggtgattg taggtcggtt tcgtcactct
     1621 agctgctatt ggctcattca agctgaacct tctggcggca cttgaggcgg catagcctgc
     1681 taggatattc cctaccaagg tagctctttg ggcatcttgc tcactgccgc ctaagagctt
     1741 ggtgccatga tagctggcct gaccaccgat aaagccgcca acctcaccga tcgtaaactc
     1801 tgtcaagccc ttggcaacac tcttggtctg accaatcaga attagtgctg cactggctgt
     1861 tgtgaacagc ccgccgatct ggtgataaag cctgtcattc cccatgaaca aggtatcccg
     1921 aaggggattg gtagccactg taagcccatc gccaacgcta cctagataaa tgttgtgccc
     1981 agcctcatac aggttcgacg ccccataagc aactgtacca ctgccaacaa caaaggcccc
     2041 aaccaccaag ggagtcgctg cccctgctgt catgacgata gccgcaaccc caaccgctat
     2101 tgtcacaagg ctgagtgcta gatctatcca gccctgcttg gccctgtcct ctgcagctac
     2161 tgcctcaaaa cgggcatgat cccgctcctg cgctgcttgg agacgcttgg cattggtctc
     2221 aagatgacga gccaccccct gataagctgt cgcaaagcgt tttatggtgt tgagctgtcc
     2281 tatatcccca acctgatagc tcccagcccg cttgggctta ctgctgtact ctgctatcaa
     2341 ggccttggtc gaagccaaaa gctccttgaa ggcggccaag tcctgactgg catgattgct
     2401 ttcgtattga atgatggcct cgtccaagcg atggatatca gtgatcagct cactataatc
     2461 cactactgtc ttggcatgac tgacaccaga gtagtgaacc aggtctgata acttagctct
     2521 ggtattctgt agtagctcaa gctgatcctt gaggtgggcc tgcgagagcc gaagctctga
     2581 ctgcagggtc ttaaagacct gaccgggtaa ctgggcatga ctattactgt ctatctggta
     2641 atagccgtcc ttatacagca agaggctagc tgagtaatca ttcatcaggc tttgcagggt
     2701 ttgtaaaagt gtcccatgca cctcactcag atagctcttg attgagctag cggtctgacc
     2761 ctgaaggcga ctgtctccaa tcaaggctga cagggcggtc tggatactcg ttatcccatc
     2821 tccccaagca ctgatcgtgg tttgggtgct ttgttgaagg gaggtaatct catcatattt
     2881 gatattatag ctcatttctt cccctaacgt tttcaatgcg atatcaaaat gtttcaccaa
     2941 taatagcaat acatttcttt aatatacctc ttttattata tcaaaaaaaa cttaatgatt
     3001 atcacaccaa gctaagagca ttgatgggta ataacatata gcttatccaa ccttgttagc
     3061 aggagtatta caaataatgt attgccaaga ggaaaagctg atataaatag gtgggacaaa
     3121 cgtggtcaag aaaaccttta acaccaagaa aaccatgata attcttgata acatcaaata
     3181 gtgcctcagc taaatgatta tgatgacctt taccaaatca ttctttatta tctgcaagaa
     3241 aagaacagtg acatctcttc gatccgatta cgaatataaa tcaagcttca aaaccgctct
     3301 tagtaccttt attcgttgcc aaaaatatct cattgaactc tcttattcaa acgctaagct
     3361 agaagcaacc aataaactga gcaaaaacat aaagcggcaa gctttggctt taggaacttc
     3421 aaagctaaga ttcccaatac ttttaacatc acaaaagaga gcaccaagct ggtcctctct
     3481 agatattagt tattagtcac cccactacag ttgacattga gcctctttga tgacactagt
     3541 cgtgaattag tgagacaaca acatagcgat tagggtcgtt gccctctgaa tagctctcaa
     3601 ccccatcaat agcagaaact gttttatgaa caatctttcg ctcgctgtta ctcataggat
     3661 ccatggtata atcttgacca gactcaagca cacgcttgga tacctttttg gtaaagtcaa
     3721 tcagggtttc tgtccgatgc tctacataat catgaacatt caaggagaca gaaaaattct
     3781 tagaatagcg gtcatgtaag aaattttggg ccagcaattg cagtgatttc aaaaccttac
     3841 catgatagcc aataacacga cctgcctctg gtgtctctat ctgaagattg atctgacgac
     3901 gattgttggt cctctcaata gaggcttcaa tatccatctc atagataatc ttggtcacat
     3961 agtcagaaat ctcctgtgca gctagctcaa tatccttact catgtccgct gcagctggat
     4021 ccagctgact cgcaccagca gctgacgaca caggctgtgc ctttgactga gtaggagctg
     4081 actgagctgt gcttaatgga cctgttggct gatgagcatc agactcagca gcccttctgt
     4141 cttgtgatcg aacagccttc atctcctcaa gctccacctc atcggggtta ataaccggtg
     4201 cattttgacg gttgatctcc tctggaacac tacgtacggc ttttttatca gccttataga
     4261 ctgttttttc attaatgcct tcaatatcaa cctgagctgg ctttttacca aagcccaaaa
     4321 agcccttttt ctcctttgaa atcaccttga tgtgtgcttt tagacgtgac aaccccaact
     4381 cttgaagtcc tttttcaatt gcttcttcaa cagtcttacc tgtaaacaat accatatcct
     4441 aaactcctat tttcttttca ttgctctctt acgagcgcga cgttccttag ctcgacgctc
     4501 tttttcttca tctgctaaac gttgcctttc ggcaataacc ttaaagggat tattaaacag
     4561 caagagctga acaacctgaa aggcattgga aactgcccaa taaagcacca caccactggc
     4621 cagattaaag cccataaaga agatgaacac aggcatcacg taggtcatga tcgttatcat
     4681 ggccgtcttt tctctagccg ctagattggt tagccatgtt gataaaaagg taaagacagc
     4741 cgctaaaata ggcagaataa agagatgatc atgtcgcgcc agctcaaccc ataaaaaggt
     4801 gccttctctt aagaaagcca cacgagtcag agactgaaac aaggcaaaca tcaccggcat
     4861 ctgaatcagc aagggcaaaa ggctcatgta aggattgaca ccatactttt tgtacagagc
     4921 ttgactttct tcagctagct tcatacgagt tgctgtgtct ttagcagcat attttttttg
     4981 cagggccttt agctctggtt gaatgtcctg cattttctgc cctgacttga tttgcatgtt
     5041 aaacaatggc agtaaaagca agcgaatcat tatcgtaaat aggataatcc caatcccagt
     5101 cgatccatca aaggacaacc attggatcgc cttggcaaaa aaataaacca attgctccca
     5161 gctactagat gattgtgctg tcacctctcc acgcccacag gctactagta gcaagacaag
     5221 cggcactagg gctgctgttt taactctttt tttcaatctc aaaaccttcc tcaagcaatt
     5281 ttgctagctt taaaacatga tgtaaatttt gtttgactgc ttgataatct aattcctctg
     5341 cacctctcct agcaataaca acgaaatcct cagacttgag gtgatcaccc agctccatta
     5401 aaacatgtcg tatcttgcgc tttaccgcat ttcgagtaac agcatttcct agctttttgc
     5461 caacagaaat ccctgctcga aaatgcttgt gctccccttt caaatggtaa atgacaaatt
     5521 ttcgatttgc catgctctga ccaagcttaa aaatcgcctg gaaatctttc tctcgcttga
     5581 cacgatagct tttcttcaaa acttaactcc catatctaaa ttattaccat tataccataa
     5641 aacattaaaa agcctcaacc cttatcaatg ggcctataat aagagattgg acccactatc
     5701 taaaggatca gaacaaaaaa tgcttttagt gaatcacggt agctgtcaag tcttgatagc
     5761 cttatcaatc atactagcaa agaaacaaaa aaataaagcc cggtaaaccg agctttatct
     5821 ccgctgactt gagcatcagc aaatatgata tccaaacaaa gacaactgaa acaatcattt
     5881 taataacaag cagccatatc aaaaatacta tttgtttatg gagagagaga gaaaacaata
     5941 ttttgattga attggggatg gaccactcca ttacctaatg atttcgtaaa tctttattca
     6001 tactagacat tatagcgaaa aatcactaaa aaagatgaca atttcctgaa atgttcattt
     6061 ttcgtcctaa aatgtcattc aacttaattt ttagcgaaaa gacttccact tttcaaaaag
     6121 ctgtttcatt ctcaaacgag agaccataca agaatcacca ttttcaaaat acaccaattg
     6181 cttagcctta tcaattcgaa caacattgtc aagattgacc aagtaagaac ggtggcataa
     6241 aaacagctta ggagctaccg catgaatctc agataagttc ccataaaatt ctaagcgctc
     6301 tgtttgcgtc cacaggcaca ccttgtgagg cgttgttgca gttgcaaaat aaagaatgtc
     6361 cttataaggc agctttaggc gggtctgcgg ggtctcaaac aaaaacatct cttctacttg
     6421 acgactcgac atcatctcat aggtgtagcg aatacattcc tcaatgcgct ctttaaattg
     6481 ctgactatca accgctttat caataaaatc caaggcagac accttgtacc taaaggaaat
     6541 aggggcgaac tctgaatgcg tcgtgacaaa aacaagcaca gcattgggat ccttctggcg
     6601 aatatctgag gctagctcta gcccacttct tgatttgtca ccaatttcaa tatctaaaaa
     6661 atacagctga tgatctcctc tctcctgaat gctatcaaac agcttttgag gatttgaaaa
     6721 cacctctaat tgattatgag gaatcctacc ctcttctaat atggacgcca caatggcctc
     6781 aatacgactt tgttgaatca gattgtcttc cagaataaaa atgtttagca tggcttatct
     6841 catttctaac aattgtctca aacggtagtg atcacttttg gttgaaaagg tgatgtgggg
     6901 atagcgctct aacacagccg agaactgtag caggcgctta tgagcatggc ttcctagctc
     6961 caatcggcta gcatcaaatt gcttggcaat atcaacccgc ttgagccttg tactattttc
     7021 aatgataaaa aatcgcttgc catcttgatt aaaataggca atggataaaa aaggacgaga
     7081 gctgccttta gctgacaaaa tagcattatc aataactacc ttgaaaagaa cgatgacatc
     7141 taacagcctg acagaagagc tagcaagcgt ttcaggaata tcgatgtaaa cagcaatgcc
     7201 ctgcagcttt gcttctaata gcttggcatg caataggctg cgaatcaccg aatcctgaac
     7261 attatcaagg gctgataatt caggtgttag ctgcctgata gagcttgctg attcttggat
     7321 aactgtttga tagaccttag aaatagcagc tatatctcca ctatcaatac tatcctttag
     7381 actaattaga atattttctg aatcatgctt aatagccctg atctcacgac aaagccgctc
     7441 aatatactga ttgtgctttt caaggtaagc aacacgctcc ttttgtgcca gagccaatct
     7501 ttgagatagc tgatccttag caaagcggtc cagcttgaca atgacccaga tgagcagcat
     7561 gaggtaaaga aaaatcatga cagagcggta acgaaaataa atcttgaaaa aatctccttg
     7621 gatattgatc atgcagtgaa ccatcacata gtagaaaagt aaggctgcat tcatccaaaa
     7681 gacccacttc tttagcttgt cctcactgat aaacttaatc aaggtcaaat caacgctaaa
     7741 aatatagcta aacaggtaaa aggccggcaa aaccaatgca tgacagacca tcaatagacc
     7801 tatgtcatta ttgatttgat gaatgctgta gcctaaaacc gctggcaaaa ggaaagagcc
     7861 aataatacga aagagcagct caacaatcat aatcgcaaac aagccattaa acagatgctc
     7921 agaagccttt ttatgaggtg caaagccaac actgacagca acaaacacca gctgatcaac
     7981 tagcagcaca tgatccagca gcagattagc aacaacaaag caggcaccaa ccaaaagcaa
     8041 tgatctaaca gctagcttaa tgcctgaaaa tgtcgaaaag atgacccagc tattcacaaa
     8101 gatcagagca taaaagaatg acatacctag cataaaataa aactctactc tttctctatt
     8161 tttggcatga ttagggtctg actaaactga taatcatgac tcctggtgcg caaggatagc
     8221 tcaggatatt tctgcaaaat ccgcttggca ttagacaagc ctatccctcg accgctcccc
     8281 tttgaggaat agccctcttc aaaaatccta ctaatcatga ccctttcgtc cttggtcgta
     8341 ttggttacgg tgaaaatctg ctgatcatca gataaaaagt aggctatcgc cactgctggc
     8401 tgggctgtct ctagagcagc ctcaatagca ttgtcacaaa aaatagatac aagcagcaat
     8461 aaatcaagct ctgagatata gctatcccga atccgatctg gaacttctag gcttaaggcg
     8521 attcctgcct tctcagcctt aatgattttt gatgatagca agctttttat cgaggataca
     8581 ctgattttac tgagctttga aatattgtaa tgcttatcgt cccaataatc cgtcgcctca
     8641 tctaccgttt gggcatagac agtctgtaca tctgacacag agccagagtc aatagcctgc
     8701 cccagccttt ctagcctctt gaggtaaact agctgaaata ccttaacacc cttataaagc
     8761 ttttctagat gctttccata ggtttccaga ttagcaatat aagcctgctg ttcctttttt
     8821 aattcctgtt ttaagaattc ctttgattga tgattaaaat aagacagtaa ataaatcaac
     8881 aatagggtaa agatgagaaa cagcacctta taagacgttg acatcattat cggggattta
     8941 aggtcaagaa agggatcagt aaatcctaaa atcataaaga gatcaatata gtaggccaaa
     9001 ctaaagagca aaaacaagct ataaaagcta ctggccttat caaacctgtc agctttaaca
     9061 atctgcttgt aatcctttcc cacaaaataa ttaatcaaag caaagcttgg gaaaatcatc
     9121 acataagcaa taaagtctag gacaaggtgt ctgacatagc tgccattaac tgaaaaaata
     9181 tagggaagta caatcgctaa aataaagcgt gataacaaat caacaaacac tccgggaaca
     9241 aaggccaaga atagagcctt taagctaaag cagggccgct tttctaaggc taatacagct
     9301 agcagcaata aaggatcaat tatcaagggc ggcaataaag caaactgatt caaaaagaga
     9361 gctgctgtca ggacaaaaat ctgcttccaa agtgccagtt taatgtctga taaaaaggaa
     9421 aaaatactaa tttctgtcac ataataaatc atcagtgata gtaataaaaa gagataataa
     9481 atatcagtca ttctgcctcc ttaccaactt tattatttta acacactttg tgtcaatccc
     9541 tattatatga attttttata taattcagca agcgcaaaaa cagtccatag ctggtttgtg
     9601 acagcgtttg caaatcagat gtcaatcatt aaagcaaatt aaaatatctg accagcctta
     9661 ccttatctag ggaaaaatat tgtataacaa ataatctaag aaaaccagtg acaatttaat
     9721 atttatttta ataatatctt ccacgctcat caaaaattaa gcagataagc ctgctggatt
     9781 atgacatcta gctatgcgct actgggcgtc gtgtcgctag ctcaagcaca ctaaaaaaga
     9841 atgaagcaaa catcagatat ctcatctctg cttcattcat gatgttattt atgatcatcg
     9901 tccagcctag accaaactac tagctgcgat agtgtttaaa gcatattggc aatatgctca
     9961 atcgattgtt cacgtccaag gaggtaaatg gtatttggca gctctgggcc atgcatttct
    10021 ccagaaacag caatacgaat tggcataaag aggttcttgc ccttaatgcc ggtttctttt
    10081 tggacagcct tgatttgtgg gaaaatgttt tctggcttaa agtcctcatc tgacatcgcc
    10141 tctagctttt ccttgaaggc cttcagaact gttggaacag tctcagctgc catcacttct
    10201 ttttcttttg cggtcagctc tgggaaatct gagaaaaata aatcagtcaa tggaacaatc
    10261 tcatcagcag agcttaattg aggctgatag agctcaacta gcttctctgc tttttcagtc
    10321 aagcggcctg ctgcttcaag aaatggctta caaagcgcat atacagcgcc aagatcagca
    10381 tgcttaaagt actcattgct catccagtcc atttttttct gatcaaaggc tgctggcgac
    10441 ttgctaagac gaatctcatc aaataaggca atcaattgct cacgagaaaa gatctcagcc
    10501 tccccgccag gattccagcc taaaagggca ataaaattaa agactgcctc tggcatatag
    10561 ccttttttgc ggtaatcctc aataaactgc agggtattgg tatcacgctt tgatagcttt
    10621 ttacctgtct cagaattaat gataagggtc atatgaccaa agacgggtgc ttcccagcca
    10681 agcgcctcgt aaaccatcaa ctgctttggc gtattggcaa tatggtcatc tccgcggata
    10741 acgtgtgaga tttgcatatc gtgatcatca ataacaacag caaaattgta ggttggatag
    10801 ccgtcttttt tctggattac ccagtcacca ccgacattgc caccctcaaa tacgatatcg
    10861 ccttttacca tgtctgtcca tttgtaaaca ccagcctcat tgaccgctaa acgaaccgta
    10921 ggcacaatac ctgctgcttc acgctctgca atataggccg ccttttcata tgctgacatg
    10981 ccaaggtatt cattgacata gcgaggtgtt tcaccagctg cctcttgacg ctcacgctct
    11041 gctgccagct cctcctcagt cacataagac ttgtaagcct tgccttctgc caataattgg
    11101 tcaatgtatt gttgataaag ggctagacgc tctgactgac gataacgctc gtgcgtctca
    11161 ggactttcgt cccaatctat accaagccat tttaaatttt ccagctgaga acgctcgccg
    11221 tcctcgacat gacgcttacg atcagtatct tcaatacgaa taataaagtc accgccatga
    11281 tgacgagcat aaagatagtt aaagagcgct gtccgcgcat ttccgatatg taaaaggcct
    11341 gttgggcttg gtgcatagcg cacacgaatt ggtttagaca ttctttttct cctatggttt
    11401 cattgaaaga agggatcctg ggctataaac cgttcctacg gtaggcttgc tctatgagaa
    11461 aatggtcgat aaggaacaaa aatacagcta atcccttgga aatctaaaga tttcaatcgc
    11521 tcctattata gcacaacttc aagcattggg cgacaaaaat caacttagaa cagctgcata
    11581 acgaaaatgc atgtaaccat tttctagcta catgcattgt tttcatctac ttctgatatt
    11641 ttgatatcat cagctgttca cattcagctt aattgtagcc tgaattgatt tgaaaaagac
    11701 cataccactg atgagaaaat cgctatcaaa aacgtaaaga tccttatgcg tttggcgtgg
    11761 cctagagcta ggatagctct ataagcagct cattggcaag cagtgctgcc tctttcaata
    11821 gcttcatagc atgcctagct atagatatta gtcaggctat tgacctgcat tgatgtcaag
    11881 ctacacccca gcaaagaaag cgacaatata ctctggcaac cacgaacctg tcatatccat
    11941 ttcaatccat caattggcaa ggcttggttt acttccaact gcttaatggc cgcctgtgac
    12001 aatatagctc tgtaaaactc cagcaaattg ctgaaggttc aggctttgca catagacatc
    12061 tccgtatccg ctaaaggtat tgaccactcc ctcacctgta ccaatagact gcataaagcc
    12121 attttccaaa tgaatatcat aatccaaatc ctgactccaa gccaccacat ggctattatc
    12181 aatcgtcatg ctgtcgccat gaagcgtgat ttttttaatc gaaccaaaag cattgaccaa
    12241 tagggttcct tctccttgtg ttgacatcac aaagaagcca ccctgaccgc taaataaggc
    12301 cttaccaagt ttttggcgct tcatggtgta gtgagctgag ccatctaaag ccaagaaggc
    12361 tccgtcattc aaacggtatt gatctacccc tagctcaaga gcaataacct gaccaggcat
    12421 tgaaggggca agcgctagct tgccactaac atcattagca atcgcctgtg tgataaacat
    12481 ggattctcct gaaaccattg aacggccaat ggcaccaacc agcttgccaa gacctgagcc
    12541 acgcccattg agcttggtgt ttaagctgat tgacggtgtg tggtaaacca tactgccttt
    12601 ttgtagaaag acagactccc ccatgtccaa atcaatttca acaagaggaa actgcatgct
    12661 gctgtcaata gtataggtca ttcgattata ggccataaca ccactccttt gtatgatttt
    12721 gttgatacaa tcaagtatag tcttttttgg cagcattgtc cactagctac tgtcgccgcc
    12781 attcctaacc agtctcaaag ccatactaca aaccgatcag ctgtcaggat ttcggcatcg
    12841 ccacctgaga catacgtcca gtggcaacat catagaccgc accactaatg accacgtctt
    12901 ttggaatcaa cggtgattgc tgcaatatag ccatatcctc acgaacactt gcttccacat
    12961 cagtaaaggg gagaaaatca cagtcagaca catctactcc cagagtatca tgaagctgcg
    13021 ctgtaaaggc ttcattggta aaggtttgcg ccccacaatc cgtatgatga agaacaacga
    13081 tctcacgcgt tcccagctgc tgctgcgaaa tcacaagaga ccgaagcatg tcatctgtta
    13141 tccgtccacc agcattgcgt aaaatatggg catcaccaag cgctaaaccc aaggcctgcg
    13201 ccacatgcag tcttgagtcc atacaggtca caatagctac cttagttttg ggctttaggg
    13261 gcaaatgagc agtcccatgt aaggcgacat aggcttcatt ggcagataaa aagcgttcaa
    13321 aatatgacat gaatacggtc ctcccagact aatctctaag ctatctcagc cttgagctgt
    13381 ctgtctatct tatcatcttt tgcctgaaat gtctgaatgc tgaactgctt tttaacacaa
    13441 gcagatagca ctagcctaac tgaaaccaga ggtaggtgag ccagccttga cattggaagc
    13501 aagcttagca gcccgccctt tgagccgcta aagtaagggc agcaagaacg tgacaaaatc
    13561 agttaattgt cattttaatt aaaaaacgaa actacggaga caaactgata aattgctatt
    13621 tctcgctatc agccagtatg ctaaactctt ctcagaaggc cttggcagtc gctagctgct
    13681 aagccaataa tactaaatta aggagaatag caatgaaaca aacaaaaata atctgcttat
    13741 tggctgctgc tgctgtccta accctaggtc ctatcagcac aggccagaca caaccacaga
    13801 ccgtatatgc cagtcaggtt agtggagaca gctgtatcga tctaggtaat ggatggttta
    13861 aatgtcctaa ggatattgga ggatgggaca ttctttttaa tcaagattac caagcgcctt
    13921 cacgatcgcc atttttcact tggatttcag gctggtttaa ctttatatgg cagtggttta
    13981 aaagcttcta agatctacta atacgctatc catatcataa ggctcttaga ggctagctct
    14041 ctaagggctt tttggttcta cggaacacta taaggacctt ccaatactac tggtcttaaa
    14101 ataaaaaaga ctaggaatag ctcccctagt cctcatgtta aaaacaacaa cctaagtaaa
    14161 gacagccttt aagacctctc ctactgtcgt cacaccaaca acctcaatcc cttttggcag
    14221 atcaatcccc tgcaatgagc ttttcggagc gtaaagcttg gtaaagccaa gcttagcggc
    14281 ttcattaatc cgctgctcaa tacgggtcac acgccgaata tcaccagtca agccaatctc
    14341 tcctaaaaag gcctcctgag ggttggttgg tttttccttg tagctagagg caatggccac
    14401 agcaactgcc aagtcaatag caggctcatc tagcttcaca ccgcctgctg acttgaggta
    14461 ggcatcttga ttttgtagca gcagcccaca tcgcttttcc aagacagcca taatcagact
    14521 gacgcgatta aagtccaacc cagttgtcgt tcgtctagca ttaccaaaaa cagtcggtgt
    14581 caccaaggcc tgcacctcag ctaaaatcgg tctgctcccc tccatggtga caaccacagc
    14641 agagcctgtt gcgccgtcta atcgttcctc taagaacacc tgactgggat tgaggacctc
    14701 cactagccca cctgattgca tgtcaaaaat accaatctca ttggttgagc caaaacgatt
    14761 tttaaccgct cgcaagatac gaaaggtatg atgcctctca ccctcaaaat aaaggaccgt
    14821 atcaaccata tgctccagca tgcgaggccc tgctagggtg ccctccttgg tgacatgtcc
    14881 tacaataaag gttgcaatat gattagactt agctagctgg agcagctcag cagtgacctc
    14941 tcgaacctga ctgaccgagc cctgaacacc cgaaatctcc ggactcatga tcgtctgaat
    15001 agaatcaata atcaaaaaat ccggctgaat ggcttcaatc tctgctcgaa tagcctgcat
    15061 attggtctcc gcatagaggt aaaaatcatt gtcggtctgt cccaaacgat cactgcgcat
    15121 cttgatctgc tctgccgatt cctctccaga gacatataaa acagttccct tatccgcaag
    15181 ctggatagaa acctgcaaga gcagcgttga cttaccaata ccaggatcac caccaatcaa
    15241 aaccaagctc cccggcacaa caccaccgcc cagcacacga ttgaactcat tcatctctgt
    15301 ctggatacgc tggtagcgaa cgccattgat atgctttagc ttgatgggct tacttttttc
    15361 tccagtcagg ctaatacggg catttttgac gtccttgacc tctgtctcct ctacaaagga
    15421 agaccaggca gagcaattag ggcagcgccc cagatatttg ggtgactgat agccacattc
    15481 tccacagata aacctcgcct ttttcttagc tataacacat ttcctccttg aatctaagca
    15541 tcaactggct acaagcacgt gaagcagcct gctaatacct tatcctcctg tcgaaccaaa
    15601 accacctgtc cgctcaccac cagcctgatc accatcagca atcaaaaaag gcataaatac
    15661 gccctgaaca atgcgctcac cagctgacaa ggtaatggtt tgatccgtaa tatttttcat
    15721 ctgagcaaaa atatgccctt cattcgcagg gttaccatag tagtcaccat caataacacc
    15781 cacagaattg atcagaacca gtcccttttt acgaggattg ctggagcgat catagagata
    15841 aagcacctca ccgtcttgca tatacgcctt gacccctgtt ggcacaagta caatctcacc
    15901 tggtgcaatg ctggtctcct ctgcaacaga taagtcatag cctgctgcat gagctgtctc
    15961 acgttttggt aataaatcag tatcagtaaa gcctgacaca agctcaaagc ctcgaatcct
    16021 tgtcatgatt aacctcaaga gcccttgtca gtgcctgcag cagctgtaaa atcacctgcc
    16081 aggacagcag acaaaagcac tcttatccct tttctttttt tagtcctctt attataaaat
    16141 attcgtaaag gaatagcaaa aaagtagggg ctgcacccca aaaatcaccg actgcccccc
    16201 tctataacgc aacaaaatgc aagagggcta aatctccttg ccggcatagc taaaccgaat
    16261 ccttggaaaa tcagcctcca aatccttatc tgccataaaa gccttggcgt cctttttcac
    16321 ctgaaccaga tcaatccctt gtatgtttgc agcatagacg cagccgcaat agcactggcg
    16381 gtaaatatca tattcctcac acatttcgac cgacctgcga tagccattat ttttcttgaa
    16441 atcactaggc aaatacttag tggtgtaaac cttttgcaca tcaatgccta catcgttaat
    16501 cgtctgtgag tttttatgag ggctgatggt caaggcacta gcaaaataat caaagcccag
    16561 ctccacagcc ttttgtgccg tcttgtccaa gcgataatca aagcaaacac gacaacgatc
    16621 cccgccctca gactctttct ccaagcctcg gacagtcttg acaaattcat ttggcacata
    16681 atctgcctcg ataaactgca cgctattacc tgttttatcg ttgaactctg ctacaaattt
    16741 ctgagtaaca taggccctgc ggtggtattc gtcctttggg tgaatatttg aattagcaaa
    16801 ataaaccgta atatcagcgt actgggttaa atattccagc gtgtaggttg agcagggagc
    16861 acagcaaaca tgcatcaaaa tgcgaggacg tatagactcc ctcgcccaga ccttggtcat
    16921 ctgctgcatg acccgatcat agtttatttt ctggtttgga ttcattctag ctagaatctc
    16981 ttgtaagtca atcattacat cttctacctt ctattgtctg tctcttttat tatagcacat
    17041 tgccttgaca tgctttgcat caaaaaactc cgccaaagcg gagtcgatcg gcaaaagctg
    17101 ttttgatggt ttttaagaat aacaacagca gcttatgtaa tgatcatttt tagaagctac
    17161 tcaaacacaa actgattgtg ataaagctcg gcataaaagc ccttttgcct tagcagctca
    17221 tggtgacttc cctgctcaat aaccttaccg tcctttagaa cgatgatttc atcagcattt
    17281 aaaatggttt ttaggcggtg ggcaatcacg aagcttgtgc gacctgccac gatagcctcc
    17341 atagcctttt gaatcttact ttcagtaaca gtatcaacat ttgatgttgc ctcgtccaaa
    17401 atcaagacct gaggatcggt taacagcgta cgagcaattg aaataagctg cttttgacca
    17461 gttgaaaaga cattctcatc atctgacacc tgagtttggt agccatcagg caaggacatg
    17521 ataaactcat gaatatgcgt tgcacgcgct gctgtctcaa cctctttttg gctgattgtc
    17581 tgattaccaa agcggatatt atcagcaata gtcccagaaa acaagactga ctcctgtagg
    17641 acaataccaa cccgctgacg cagactatcc aagtcatatt ccctaatatc acgaccatca
    17701 aaggtaatag agccagcatc aacatcataa aaacgattaa tcagattcat gatcgtggtc
    17761 ttgccagacc ctgtcggtcc aacaacagca accattttcc cctttgaagc tgaaatcgac
    17821 acatctgaca gaattttttg tcccggcaga taaccaaagt caacatgctt aatctcaacc
    17881 ccttctttta atgctgtaaa gacaggagca tgctcagggc gaacctcttc tttttcatcg
    17941 aacatttctt ggatacgacc agcacctgta aaggccagct gcaattcacc ccagctagag
    18001 gcaatctgca taatcggttg ataatactgc tgtgaatact gaacaaaggt caccaccaag
    18061 ccaagagcag cagctgttga catggacttg tcaccaagga caatggttga gccagcaaag
    18121 atgacaatag ctgtattcaa aagactcatc ccattcatca caggaaacag cagaccagca
    18181 aaaaggcgtc ccttaaaggt tgctgcacgc accctctcat tgtgctcaat aaagccatca
    18241 atagcatcct gttgcacccc ttgaacaata atagccttct ggccagaaat cttctcgtcc
    18301 atgtaagcat ttaaagcact gacctccttt tgctgcaaat cagtatattt gcgggccatt
    18361 gtaatgatga caacgagaag aataagcgcc acaggggttg aggctatcgt taccaaggcc
    18421 aagcgactat cctgcctaaa catcatcagc actagaccaa tatacaaagc aatatttgtc
    18481 aagacctgaa tcagagattg gttcatggag ttttgaatat tatcaagatc actggtaaag
    18541 cgtgatagaa tagcaccgtc cttgtgacta tcaaaaaagc caactgtcaa gcgctccaat
    18601 ttgccaaata agcccttacg catgcgattg gtcgaatgcg aaataaccct tgtaaagagg
    18661 agactataaa taagattagc cactgctgta aagagataag ccaacaatag ctttcccata
    18721 accgtcctaa aaggcgccat agagggctca actaagggct gacccgtcat tttgctaagc
    18781 gcctgagcct tgtaatagcg ctgcacccat tctcccagct cagctagaga gtctcccaaa
    18841 aagacagggg ccttaacctg caggtaggtt gccaggacaa tagcaaagaa tatcacaaca
    18901 aaagagagct tataacgttt aaaataaaac cagaaaaatc gcaggatctt cattagttct
    18961 cctctcttcc cttttgagtt tcgtaaattt cacgataaat cggattggaa gcaaccagct
    19021 cagcatgcgt cccttctcca atcaatcgac cattatcaag aacaagaatc ttatctgcct
    19081 tgacaactga cgatattttt tgtgcgatga tgactgttgt tgtctctttg agctccttat
    19141 tcaaggcctc ctgaacaagc ttttcagatt tggcatctag agctgatgtc gaatcatcaa
    19201 gcaccaaaat cttaggattg ttaatcacac cacgagcaat tgacattctc tgcttttgac
    19261 cgccagaaaa attattgcca cgctcttcta cctcactctg gtagccagcg tccatacggt
    19321 cgataaattc cttggcctgc gcaatgcgtg ctgcattttc taaagccaat tggtcagcat
    19381 agggattgcc ctgacgcaga ttatccgcaa tagtcccaga aaaaagaata gccttttgca
    19441 gcacaataga gacggtgtcg cgcagagtct cttgactgat gcttggcaga gccttaccac
    19501 caatcaggat ttgcccttcc tgtgggtcaa acaaacgcgg aatcagctgc gcaagggtcg
    19561 acttgccagc acctgtcgca ccgacaatac caaccatttg accgggctca acctcaaacg
    19621 aaatatgctt tagagtggct tcactgtcat ttggataggt aaagctcaca tcatcaaaga
    19681 caatactgcc tgtcagctcc tcctgctcat ggttaacaaa ggtcatagca ggctctgttt
    19741 ctaaaatctc cctgatccga ccaatcgagg tcaaggcacg acttgcctgc attcccataa
    19801 aaccaaccat cgtgatcgca aagctgattt gtcccatata ggtcataaag gaagccatat
    19861 ttccaataac agcaggatct gttttgacca gccctgaaac cagatacaag gacaaataaa
    19921 tggccatgta agacaccaac atcaaaatag gctgcatgat tgaaaagcca tagccgataa
    19981 acaaattcaa gcccagtagg tcatttgaag cctccttaaa tgtgtcatac tggctttttt
    20041 cctgaacaaa ggacttgacc acacgcacac cgcgtaggtt ttccttagca atctgattga
    20101 tcctatccat caagcgctgg aagatcccaa agcgaggacc catctggctc atcaccagcc
    20161 caatgactac cattgtcatc acaaccacaa gcaccaagac ccaccaaagg ctcggtaagg
    20221 cctgcaccgc taaaataaag gcaccgacaa ataaaatcgg caagcgcaac aatatctgaa
    20281 aaagcatcat cacaaagttt tggatttgat taatatcatt tgtcattcta acgacaagat
    20341 ttccagcatt gaaggcttcc acattggcat aagaaaagga ttggatcttt ctaaaggtct
    20401 gctcacgaat atcagcagat accccttgag caatcttggc agacaagatg gtattgaccg
    20461 cacctgacac caagccaatc cctgctatca ctaacagcca aaaacccacc tctgcaatcc
    20521 ttgtctgatc attttccata atagcagcta gaacatcttt gaggtaatgt ggctggagca
    20581 gggcactggc tacgacccca gaaatcatca ctagggacag agccgcatac catttatact
    20641 tcatcacagc atttctaagc atctgtatct cctttataag ctcgtatatt ttgtttcagc
    20701 tgatcgataa ccttttttac cgtcagcagc tcttctcttg aaatttcctt gaaaaaatag
    20761 cgctcaatat ctctgcggca ctcctttaat accggcagct tagccctacc agccgaggtc
    20821 aagacaacct gcttgcagcg cttatctgta gccgaggcaa caactcgaat aaagccattt
    20881 ttttccatac gcttcaccag attactcgta accgattttg agatttgaag ctccttttca
    20941 atgtccttga caaaaatgtc tctgtcttga tggcaatgca aaaagacaag aacatgccct
    21001 tgtggaccag caagatgctg gaggtcatac tttttagcaa tctcttcgct aatttgctca
    21061 acctgatggg tcaattcacg aagctcagca atgattcttg gcatttcctt cctccttagt
    21121 tctcatgata accattttag ttctcttggg aactattgtc aaccaaaaag gcttacgatc
    21181 tgactatctt ccctgctact taccctttgc tagcaccact gagctgacag gctaggccag
    21241 cagacctttt ctattagagt taggccttgt cttatgatat aataaggtga ttagctctta
    21301 aaggagaata aaaatgccaa aacaaaaggt agccattttg ggacctggct cttggggcac
    21361 agccctggca caggtcctaa atgacaacgg acatgaggtc cgactatggg gaaatatccc
    21421 tgaacaaatc aacgaaatca acacacgcca tactaatagt cattatttta aggacattgt
    21481 cctagatgaa gccatcaagg caacccttga tttgaaggaa gcattggctg atattgatgc
    21541 tatattgttt gttgtgccta ccaaggtgac tcggcttgtt gccaagcagg tcgctcaggt
    21601 cctagaccac aaggctattg tcatgcacgc ctcaaaggga ttagagcctg gaacccatga
    21661 gcgcctctca acgatcctcg aagaggagat ccctgcccag ctgcgcagtg aggtcgtggt
    21721 tgtgtctggg cctagccatg ccgaggagac catcgttcgt gacattaccc taatcactgc
    21781 agcctcaaag gacatcacag ctgctaggta tgttcagacc ctctttagca accactactt
    21841 ccgtctctac accaatactg atgtgatcgg tgttgaaacc gctggcgctc tcaagaacat
    21901 cattgctgtt ggagccggtg ctctgcatgg ccttggctat ggtgacaatg ccaaggctgc
    21961 tgtcatcaca cgcggtcttg cggaaatcac acgactaggg gtcaagcttg gggcagaccc
    22021 tctgacctat agcggcctat ctggtgttgg tgatttgatt gtcacaggaa catctgtgca
    22081 ttcacgcaac tggcgagctg gtgctgctct tggtcgcggc gaaaagctca aggacatcga
    22141 aaacaatatg ggcatggtga ttgaaggcat ttccacaacc aaggtagcct acgaaattgc
    22201 ccaagagcta ggggtttata tgccaattac cagcgcgatt tacaaatcta tctatgaagg
    22261 tgctgacatt aaagaaagca ttctgggcat gatgtcaaat gaatttcgct cagaaaatga
    22321 atggcacaca taaggaacca caaatcaagg aggaactcat gacaaaggtc agaaaagcca
    22381 ttatccca
//
LOCUS       DARYVE010000030        22359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYVE010000030 DARYVE010000000
VERSION     DARYVE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVW25_001113"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVW25_001113"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1378750.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVW25_001114"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVW25_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1378751.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVW25_001115"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVW25_001115"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1378752.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVW25_001116"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVW25_001116"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1378753.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TVW25_001117"
     CDS             complement(6925..7623)
                     /locus_tag="TVW25_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1378754.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TVW25_001118"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TVW25_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9565..11244)
                     /locus_tag="TVW25_001119"
     CDS             complement(9565..11244)
                     /locus_tag="TVW25_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378755.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(11419..16323)
                     /locus_tag="TVW25_001120"
     CDS             complement(11419..16323)
                     /locus_tag="TVW25_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1378756.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            16676..17503
                     /locus_tag="TVW25_001121"
     CDS             16676..17503
                     /locus_tag="TVW25_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1378757.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(17579..17932)
                     /locus_tag="TVW25_001122"
     CDS             complement(17579..17932)
                     /locus_tag="TVW25_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1378758.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(17936..18448)
                     /locus_tag="TVW25_001123"
     CDS             complement(17936..18448)
                     /locus_tag="TVW25_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1378759.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(18905..19459)
                     /locus_tag="TVW25_001124"
     CDS             complement(18905..19459)
                     /locus_tag="TVW25_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378760.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            19670..20299
                     /locus_tag="TVW25_001125"
     CDS             19670..20299
                     /locus_tag="TVW25_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1378761.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            20758..21843
                     /locus_tag="TVW25_001126"
     CDS             20758..21843
                     /locus_tag="TVW25_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378762.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            22029..>22359
                     /locus_tag="TVW25_001127"
     CDS             22029..>22359
                     /locus_tag="TVW25_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TQXA domain-containing protein"
                     /protein_id="HEL1378763.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQA"
BASE COUNT         6440 a         5379 c         4403 g         6137 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt acacttttat tataaaaggt attttctgtt
     9121 tagtcaagag aaaactgttt cttttacatt tctgttattt tacagttata tgtcacatct
     9181 gatttggttt aatttttctg aaaaaccagt agataaggca ttttaagcat tttttgatga
     9241 taagataata tcacaaaaca ttaattatat gacaattatt gtttttaatt attagaattt
     9301 ttaatcaaaa ctatcctgca atcagctgtt tagccatttt aaaaggcaaa caaaaaccat
     9361 gccacattgc aatgacatgg ttttcttcaa gaaaggagcg agctttggtt tggtactttc
     9421 tacaactgat ctccaatagc agctgctcct cgttagtccc tgagccacag gtgactgagc
     9481 tttcctgcgg ctactctgat agtaccagct actcttacaa ctgcataaag cagtggctgc
     9541 cagccaagct aaagctaaac aatattactc tgttatagct tggtctgctg acgagctctc
     9601 aatggtcatg tgattgaggt agttgtcatc agccagctga gccttaaact ggtctccgac
     9661 ctttaggaaa ggcagacggt cactagtttc actgcttgcc ttgattttat aaatctgacc
     9721 cttggaggaa atgtaataaa ccgttgttcc tgagataatc tggctggcca attgctccac
     9781 ctgcccagta atcatcttga ccttctgatc attggtgtct gacactgaca gcgagcttgt
     9841 gtccttatct gtgaattgtg agattaaggt ctgaatgtca ttattcactg ttacctgctg
     9901 ataatcctct gcatcaacca aggcatagga ttttatcaga ccagccccgt ccttcaatga
     9961 gataaggtaa taagccttgt catttaactt gactagggtt ggtgcagttg cagtgtattt
    10021 cttctcttga acttcgccct cggctgattt catggcagag gcctctgttg cagaaggcag
    10081 cttatagtta gtgacctctc tggtacgcat gttaaccaaa ataaagccga gatttgacga
    10141 atcagctgtt gctgaggtga ttcctgtata gaggtaaatg tctgagccga tggtaatgta
    10201 gttatagctg tctgttgttt gcttgacatc tgtctggcta aagacagtgt tccaatagcc
    10261 cttttgatag gtgtaatagt cattaaccct ctccaaaaca ttgtcagcag aatagacacg
    10321 atcaacccat tttggaacgt cctttagctc atagtattga gacttgccgc taaccgcgtc
    10381 taacaggatc acacccgtcg gctcctgaga ggacaggcca aattttgggg cgtaggttgt
    10441 tgcgacatag taagggttac catcgtcatc aacctcaaat gacgggtctg aaaaaatggt
    10501 catcgggtac tggaagcgca aatgcctcat ggtgtctcta aacataaatt ccgaatgaga
    10561 atacttcata ggctgattta acttgactag ctctgcctta ccagttgtct gattgacctt
    10621 gacataatag ccaatgccgt ccttacgatt ggttagccat ttccagaagg atttgtactc
    10681 caagggagaa acacgataag ggagcttgcc gatcgtaatc tgacggtact catcagaaat
    10741 accaaactgc gataccttat caatggtccc aagataagta tctccaatct tttcagccga
    10801 atctcgatcc agcaatgcca aggctgacag atcagtgtct ggaaaatcct tgttaaaatc
    10861 agcgtccttt accttaatca catgagcata ggacttagca cgaaacattc tagtattaac
    10921 agctaacagc aaggacaagc cagcaatgat aacagcaagg gcaagaccaa gccactttat
    10981 gccaccggtt aattgcttga gtgaaagacc tgaggtcacg tccttgcggc cagacttttg
    11041 cgtgaaaaag ctggtcactg tttttttcaa cccaaacaag gacaggataa aaagactcac
    11101 catcgccaag ataagcgcaa gaatcacgaa aaaccaaaat tctaagctca tcacgttcat
    11161 tggcggcaaa taaatccagt aaaagccagc caggatcaag ctgtctaagc caatcagcac
    11221 caaagaagca actttttttg tcatactaat ctcctcgtca caccctaagg ctatcagggg
    11281 tattcaatat cttctcaccg ctattgtacc acatttcccc tcaaaagatg acatctcagc
    11341 cagacatttt tatcagctct tagagcacct cagctagaat gatcaataca gctgacaggc
    11401 tacgctcata gagcttgctt agtacttctt ttgacgctgg caagagcctg ctgctccaag
    11461 actgagcaag cctagcagga ctagattgac cgctgcttgc tcacccgttg atggtaggac
    11521 ttgggctttt ttaactgctt gtgctgttag ggcagagcta gtgattgatg agccggtata
    11581 atgagtcaag cctccagcct gatgttctag ctgaggctgc ttagctttga taacctcaaa
    11641 ggtaagctca atcacgccat tatgtgatac ctctagacct ccttgaccga ttagctgata
    11701 gccctccggt agctcaacga ggacctcata gcttccttgt cgcagtgttt taccataggc
    11761 acttggaaca tagagagacg gagctagaga aatcaactga ccatttgctg ctttcaggct
    11821 gaccctgctg ccttctggca agacttggtt aaacaagagc caaacagaag ccacaatagg
    11881 ccttgtcatc tcaaaggcaa ctgaagcaag ccttgtatcc gcatctagac taaagctaac
    11941 caagttgtca gaccttagct caaacagatg attatcataa gccaagagct caacggtgta
    12001 gcgtccaaat ggcaatatca agctattagc tgagctattg aaatagtcca actgctcgat
    12061 tggcttgccc tgctcatcac gaataagata agtaaaggct ggctcttttt tgttctcaag
    12121 cacatcaagt gccaaggcaa cggacactac tcccttgtct ggtcctacag ctcgcaaagc
    12181 agctaagctc atataagcaa tctgacctgc ctcgtcttcc actagataat aataatctgc
    12241 ttctgcaacg ccttcaacct taggaatggt gtaggtgccg tctgcatttt gagcaatcat
    12301 caccttatta tccttgaatc tgatcagctg atcttcgaca gttagatcaa acttgcgtcc
    12361 atctttcttg acaaggtaga agacctcttc tctaacaata cctattggac tttgtccctt
    12421 gcttggtccc ggacgaaaga cctcagtagc accatcagct tggaagctag ctggcgtaat
    12481 gactggcttt tgatggctaa ctgtcaccgc ataggcctct gcttgaggca taccattagc
    12541 gtctagataa gaaacaacat agcgataatg tcctgacatc accctagctc ctgaggctct
    12601 tgtgccatac caagcggtgc tgtcaacatt agccacgctt gcacctggtt ggctagacca
    12661 gattgggctt gtcatagctg tatcctcctg ggcaaagacc gttaccttta gatcttgata
    12721 tacttgatgt ggcaagccct tgaatgccac aaaatccttg tttccatcat cattcggcga
    12781 gatgacagca gtttgaccta atttagccaa acgactctgt ggtctattgc ggctaataat
    12841 gagaagctct gcttcatttg tcaccagtcc tgtatctgca gcagtcatgt tgaggttatc
    12901 actgtagctc agctgatgct gagcattaat atcagttagg gtcaatgcca gctcagcctg
    12961 accgattttt tctggcaagt gatttcccag cttagcaatg gcaacattgc ctgcaaaatc
    13021 ctcgaccatg taataaaaat caccaagcgc cacctgatca actggcagga caaaagagcc
    13081 atctgctaag cgctcaacaa actgcttatt gtctgatacg gtcacatact ttaagccatc
    13141 attaatggta atcgtataag gcttgtcatc ctttgtttcc aagtaaaaaa cactatctcg
    13201 aagaacacca gcctgaccgc gatcaagcca ctgagacggt ctgaagcgat gggtcacagg
    13261 gttatagctt gctgttccta gctccggcgt ttgacgatcc acaatcacct caaagaccat
    13321 ttcttgacgt ttcgctccta ccacatctgg ataataagaa accacataat ggtatttgcc
    13381 atctggtagg tcagctccgg tcagcgattt accactaaag cctgtttcta acagcgttgt
    13441 tgacttggca aagcgaatat cactgttaaa gtttttatcc ccttgaaggg ctgatgggct
    13501 cgtccagagc aactccttac ggtctgtatc tgttccctta tagaccctgg cttgcaggcc
    13561 ttggtattta cgtaagaaca cccctttgaa ggcagcaaag tcttgattgt tgtcgccatt
    13621 tggagagata gccaacacag gatagccaac tgcatttcgc tccaacacaa atttaccgtc
    13681 tttattacga aaggttccta gtgtgtgcaa gccattgtca gcaatagtag tcatagagac
    13741 attggtatct gtaccaacag tcaccagccc agtaaaatga ttgccgacat aaatctcgtc
    13801 ctttagccct gagctgtcaa aataaaagcc agtttttcct tgagccttta gctcataaat
    13861 agaggcttca acaacaggta ggttttcaaa ggctccctta aagccaacaa atggaatgtt
    13921 gatgttatcc ttgtgctcgt ccttgctatc cacaaagcga acaaagccct ctagataata
    13981 gccatttggc atttgcttag agagttcctc tgtaaagttt gaggcatcta gggtaatggt
    14041 aatggtcttg tgtccttgag caggtacgtc aacctgttct ccctgatagg ttttcagaga
    14101 tcttgaacgt aaggcaaaac gtccttcctt agtatccacc tgatcagtca acaattctgt
    14161 ctggtagcgc agcgacttag cctgattaga caagttatgg attgtcacct caaagcttat
    14221 ctgatcagtc acatttccaa gagaaatact gccatagttg tctttacctg tcaggtacag
    14281 accactggtt accgcggtct ctatattcaa gagccctgct ccctgctggc gtggcgatgt
    14341 ggtggtattg gtcttagggt tgatgtggat ctgagcatta ctcatcagta tatttttgac
    14401 cagatctgct agcttatcct tggcaagctg tggttgaagc gcttctagat attgcttgac
    14461 caaaaggctt gcccctgcaa tgtgtggggt tgccatacta gttcctgact ggctgccata
    14521 gtgatcatcg ttgaaggtcg agtaaatatc tccacctgga gcagtgatgt caggcttcaa
    14581 atagccatct gaggtcaagc cccagttaga gaaatagttc atctcatttc ccttttggct
    14641 aatggcctta gagacctcag catcaaaggt cagagtgcct gttccattgc catttaaagc
    14701 agccattgcc atgccaaatt catgagagat aaaggcagat ggcagcacca tcccctttga
    14761 actcagacgc atggtgcggt tagccttgcc tggctcattg ttaaaaatca agaccccagc
    14821 tgccccgtac tgcttggcct ctgctataat atcgtcgtat ttccgattag gatcacgctg
    14881 caccaagaca atcttgccac tcacttcgcg ttcttggtag ccttcttttg tcaaagcttt
    14941 gacataaaca aatgagtatg gtacatcaaa gccaagacta gtcttaatgt ccttgaaatc
    15001 aacagattcc aaatagatag cctttccatg atttaagtca gccctatctt tcaagccctc
    15061 caccgtcatc agacgctcta taatcacttt gttattaata gacgcaactg aggtaggagt
    15121 ccggcctgct gatggagccc ccactaagcc ataatcagga tttgtcacca acgggtctgc
    15181 atgatctgac ccaaaggcac gctcattacc tgcagcaacg accacagaga caccagcctg
    15241 ccttgccttt tcgatagctg ccatcagggc acgattccca ttcaattgag acccattggc
    15301 cgagcccaga cttaaattaa tcacatcagc gcccaatgcc acagcatctt cgatggcttt
    15361 aataaataag gggtccccag ttcccatcaa atcatgggta aaaacccgca taaacatgac
    15421 ctgagcctca ggagcaatgc ctaaaaagcg ttcgccagct gctgccgcct tgagcccatt
    15481 tccagctgca atgcctgtca catgcatgcc atgcgattca tatttgctgt catcatctgt
    15541 atcttgccag tcaatgatag ttcctcctga tgtgtcatca agcttgatga ccgtttcctg
    15601 aggtgcctct attgactgcg gacggttcct cctaatatca atctgctgca caatcacatc
    15661 aaaatccaag tcgtcaaggc cctcaaacgg atcgtccttt atctccttta ccttatcatt
    15721 gttttccaca tagttgtggg caaagactac cttatcgctt agccagacac cgtactgaat
    15781 gcctgctgct tttttgcgct ggtcaatatc tgcctttgat gtaaacttag cagctgctgg
    15841 atttgtaatg cgcatggcat ggtgactagc gtcaatacca gtatcaataa cagcaataac
    15901 cttaccttga cccttatagc ctctattcca agctccttct gtttttatcc agcggtgagt
    15961 atccatattt actggaggta gctcgcgcga ttcttcttgc tgcttgactg attggttaga
    16021 ttccgttagc gcttccattt cggaagaaac taatccagtc gccattgcct cctctgtctt
    16081 ttcctctgct ttacttgact ggctgtcgat gtcctgagca ttaacagcag ctccctcact
    16141 agcctgagag acagacaata cctcccttga ttcttgatgt tgtcctgctg acacgtgagc
    16201 tgagctaact ccctgctcct cagccacaac tgatcccatc cctgtcagaa aaaggattcc
    16261 gatcaacaca gaaaccattc ctgatttata tttcctcagt gagaagcgtt cttttttctc
    16321 cacttgatgt cctcctagat ttattaaaaa aggttatttt aaacaaatga ttcatttatg
    16381 ttttaatcaa taatgtctaa gctatttaac cattttttaa tcacaaaagc aataagacta
    16441 gaagctctca gtttatgtca ttttttaatc attcaactca ctgaaatgag gcctctcaga
    16501 acctgtctca tcaacagata aggctaaact cagccgctag acttcaaaaa tgtcacacca
    16561 tttttagaca ttacctgtcc tcatacctat aacagaacca agcttccaca gtcgccttgg
    16621 ccttattttt ttgttacaat ataggttaag attatcattt agaaagcgaa gaaaaatgaa
    16681 actcatctca tggaacattg attctttaaa tgctgcgctc actggtgaat ctcctagagc
    16741 cctcttatca cgcgctgtac ttgatactct cgtggcacag gacgctgata ttattgcaat
    16801 tcaagagaca aagctatctg ccaaaggccc taccaaaaag caccttgaga gcttgcttgg
    16861 ctactttcct aatcatctca atgtttggcg ttcatctgtt gagcccgcca gaaaaggcta
    16921 tgccggaacc atgttcctct ataaaaaaga gctcaatccc attgtcacat tcccagatat
    16981 cggagctcct accactatgg acgctgaagg gcgtatcatc accctagaat ttaacgattt
    17041 ctttgtcaca caggtctaca ccccaaatgc cggtgatggg cttagacgct tggaagagcg
    17101 ccagctctgg gaccaaaaat atgccgacta cctagcccag ctcgatgccc aaaagcctgt
    17161 tttggctact ggtgattaca acgttgccca caaggaaatc gacctggcta acccagctag
    17221 caaccaccgc tctccgggct ttacagatga ggagcggctt ggctttacga acctgcttaa
    17281 ccgagggttt acagatacct ttcgctttat tcatggcgat attccaaacg tttatagctg
    17341 gtgggcacag cgcagcaaga ccagtaaatt gaacaatacc ggctggagaa ttgattactg
    17401 gctcacgtca aatcggttga ttgataaggt tagtcgctca gagatgattt cctcaggaga
    17461 acgtcaggat cacacaccga ttttattaga aattgatcta tagactagaa gcattcggac
    17521 aaatcaaccc agacattaaa aaaaaatggc tctgcaagag aaccgttttt ttaatcgctt
    17581 aaagacctag atccttatag gctgttcgat accctacctg caagacctga ttatcctgta
    17641 agaggatcgg ccgcttaatc agcatgccat ctgttgccaa aagctccgct gcctcctcaa
    17701 cgctcagtga attaacctta tctttaagcc caagctcacg ataacgcata ccactggtat
    17761 tgaaaaagct tttgaggcta taatctgaat gctctagcca ttgtttcagc tgctcagctt
    17821 tagggggatt ggccttaata tcaatgatat caacctcaga aaccagggtc tttagctcag
    17881 caagggcttt ttgacaggta ctacactttg ggtattggta aatggtaatc attagctact
    17941 ccttattaac actaatttgc tcgtgcctga gcaaccaggc cttcttttca agtcctccag
    18001 catagccaat caagcgacca tcagcagcca gtacacgatg acagggaata aaaatactta
    18061 aaggattacg tcctatggca ccaccaacag cctgagccga acgacactgc aggcgcttgg
    18121 caagctcacc atagctcaag gtctctcccc atcttatcgt ctgcaattct cgccagacag
    18181 ctcgctgaaa atcagtaccc tgtggagata agcaatcaag catgggatag ggcttcctct
    18241 caaagtaagc gtcaagccac aaacaggctc tttttaacag ggcatgctgc tcctgccaga
    18301 tgggctgcac tttaatccca gcctgaaaat acctttgacc ttcaaaccag gctcctatca
    18361 aagcaacatc agtcgcaacc aaggatattt ttcctaaggg cgattgatac acacactcgt
    18421 acaatggcaa gatctgacct ccccacataa tagcttattc ccttgactat ttattataag
    18481 aaaaagccta gctaaaggca agaaggagcc ctctgacacc acaacaaacg catgaaaaaa
    18541 caatagcggc tctttcaatg ctgccataca atcgttagtg tcaaaagtcg cttactatac
    18601 agctgccccc cttgaaaaac gaagctggaa agacacaaca tgctaaagct gtttcacgcg
    18661 ctggtgcctg attagatgtt cttctaatta aaggccaatg ttctgattaa aaagtcattt
    18721 catgcgctga tacctactca aataaaaaca catagcgtgg ggctagacca atccctcaca
    18781 agtcatcaat agttcgtcta tgagctacac tttatcacat tgggataggc agacatattt
    18841 gccggctcag ttgtacttgc ctgatagcta accaaaagcc cgataagctt tttccgatcc
    18901 tatatcaata gctgtagcgg ctatcctcgc taatctcctg ataagcggct ctttcatggc
    18961 ttttcttaat tttttgatag gctaagcgct cgccatcaat tggtaccttg ccacagtaaa
    19021 caaagcctaa cttttcaatg atatgccgca tgacctgatt atgctcatga gtatctatcc
    19081 gaaaatctgg tccatgctgc ccctcaatga gcccttgcaa aaaggtctga gcaattccct
    19141 gaccagtcct atcactcagc accgccacac gatgaaaggt cacataacgg tggtgattat
    19201 gctgccacct gccatcataa atcttgtcgt aggcgtcctc ttggccatca ataacagccg
    19261 cataagcaac aatctgcccc tcaagcaaag ccacatagcc ctgcccttgc aacacatcag
    19321 cagcaatatc ctgataagca ggatacccat ctgctttctg ccattggctg gagcctgatt
    19381 gggctaaggc agacttagct gaattgatca ctgtcatgat ctgactaagc tcattaggaa
    19441 aagcaagtct aatctccatc gttcacactc acaatctatt ctgatttgat gatgctatgc
    19501 taccgcaaaa agccttacac cttgtcactc tgctagggac acctcatagc ggtatgcctg
    19561 cttctcatct cagctgagta tagcacaata gtcatcattt gacaaaaagc ctcttcaagg
    19621 attgccagca atcatgctat aataaagtaa atcacaaagg agaaccatta tgattaaaga
    19681 attttgtgct gaaaacctaa ccatgctaaa ccaattgacc agccagtcgg tcaatcgtgt
    19741 tgagctctgc gacaatcttg cagtcggtgg caccacaccc tcttatggtg tcatcaagga
    19801 agcctgcgac ctcctacatg acaagcagat tagtgtcgca acaatgatcc gcccaagagg
    19861 aggtgatttt gtctataacg accttgaatt gcgtgctatg gaagcagata tcttaaaggc
    19921 tatcgaagca ggaactgatg ccttggtcat aggcttactc actaaggaca accagcttga
    19981 caccgatgct atcgaacagc tcctaccagc tacacaagga ctccctctgg tttttcacat
    20041 ggcctttgac ctgattgctc gcgaccaaca aatcgcaagc ctagagcagc tcattgacta
    20101 tggctttgta cgaatcctgc ttcatggctc aagcgatacc agatccatct atgaaaacat
    20161 tgaccatatc aagcagttag tcaaggctgc tcagcaccga atcgaaatca tgattggtgg
    20221 aggtgtcaca gctgataact gccaagagct aagtcaacta acaggaacag ctattgtgca
    20281 tggcacaaaa atcatctaac tatcagctca aataaaggaa aagtcactcc ctacaaggag
    20341 gtaaataata gcagcccttc tcgttgaagg ccatacctga gcccttagac taggctccta
    20401 gcaaactaat agtataggac cttcgctgcc tttacatcaa aaaggctgcc gtccagaaaa
    20461 agagaaagcc acacattgat agaaaaccat agctggctct actactatca gtatctatca
    20521 tcagcttctg agctgcctaa aagtttcggt gatcattaac aagtacagac tatttgtttc
    20581 taaattagat cataaaacag acaattatag gaagcgacaa gtgaatcatt attcattttt
    20641 tattgattac tatgatacta taagtaagga tagcgctttc tttttgtctt tgctttgcct
    20701 gactattagg ctctagattt attttttacc atactaatat aagaatcgga ataaataatg
    20761 acaacaaggt atttttataa gctattgcta acgatgttga cactagcatt aggaggattt
    20821 tccctatctg cttgccactc caagattagt aagccctatc aagtcgctat ttttgacaag
    20881 gatcatgtta ggacctttat ggaaaaagct gacagtctgg tgcctgttga gaccatctct
    20941 cgaacacagc acaagctatt tgagcgagaa agctttaagc aggccaagca agggtatttt
    21001 gcaaagacaa gagaaggaaa tgacctcaag gttctgttaa ctcacattga tcaagcaagc
    21061 ctagaagaaa aagtccttca tgctgatggc aatgacgcct acacctctac aactgatggt
    21121 gattactttt acacaacagc tgtctttgcc gatcgtattg actgctacaa gtatgaccgc
    21181 cacttgaaaa aacaggctca caagtctatt ctaaatcaag acaccattaa tgccagcaat
    21241 cagtttctgg tgattgatga cgctctgtac ctgcttgtca gcgctgtaga catcaagagt
    21301 cagcagccca aaactgagct atggaaaatg gacaaatcct ttactatcac tgatcggata
    21361 gatctggacg aaagcactgc ctatctgcgc atggtcaacg tcggacgaac cctttacatt
    21421 acccaggctg ctgatggcat tttagaaact ggagaaccta gacctggtaa caaggtgatg
    21481 acctatgact tagatagcgg tcaaaagtcc tatctcatgc ttcatgtcaa tagtcctaga
    21541 gccatttacc accatgccaa aaccaatgag cttatcatcg aaaatgatca gcattataat
    21601 cctgactttg catggaccat ctaccagcta gataccggag aggagagaac cattcgcttt
    21661 gaggagctag ccggtcagga gacaagctct ccctacttta tgatgacctc aagcaactac
    21721 tacttcctct ttccaaaaag gctttaccga tacgattgta gtaaccatca gatgacctgc
    21781 atcaacctag atcagtacgg agtgacgcac gcccatgcct tgatcgctaa gcccacacca
    21841 taaatcacaa caggcctaat caccactcat tcatctacac cccaatgctt agacaaagca
    21901 gtgtactgac ccccaaaagt tggacacgac atattagtga aaggacttag ccctgtgcaa
    21961 tacagaacta aatcctttca ctaatatgtc gtgtccaact tttgggggtc agtacacttt
    22021 gggaaagtat gtatgaatct ccagaaaaaa taccttatca actacctcta tatgacaagt
    22081 atgagggaaa taatagttta tttagagata atgcctcacc aaattttagg gcggatgtca
    22141 aagatattac agctacttta gtggctgttt taagtaatgg ttatccaacc gggaaaagca
    22201 gtttttgtaa agactactgt cccgatgaaa tcagggcaag acaattaacc caattagcta
    22261 tttggtattt tacagatggt atttctgaag aaacgttgaa atcaaattat agtctaaatg
    22321 atcttgaatt tcaaggatta aagtatttaa tacaggctg
//
LOCUS       DARYVE010000031        21923 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYVE010000031 DARYVE010000000
VERSION     DARYVE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21923
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..388)
                     /locus_tag="TVW25_001128"
     CDS             complement(<1..388)
                     /locus_tag="TVW25_001128"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378764.1"
                     /translation="MLDFMSNFWGAVQSDSDDIKYRIDSYNRYGIDGLAGKLYTNYIV
                     GKISNDELNYGLQKIFAKLISTKMGRMVPIENNNGSPYVDSGNAGLITVLILLDPEKY
                     KDIIIELADSLQFEFAQRPGYFNGMLG"
     gene            433..1611
                     /locus_tag="TVW25_001129"
                     /pseudo
     CDS             433..1611
                     /locus_tag="TVW25_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            1571..3019
                     /locus_tag="TVW25_001130"
     CDS             1571..3019
                     /locus_tag="TVW25_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1378765.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            3047..3235
                     /locus_tag="TVW25_001131"
     CDS             3047..3235
                     /locus_tag="TVW25_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378766.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            3240..3497
                     /locus_tag="TVW25_001132"
     CDS             3240..3497
                     /locus_tag="TVW25_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378767.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            3674..4243
                     /locus_tag="TVW25_001133"
     CDS             3674..4243
                     /locus_tag="TVW25_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1378768.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            4256..5143
                     /locus_tag="TVW25_001134"
     CDS             4256..5143
                     /locus_tag="TVW25_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1378769.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            5155..5511
                     /locus_tag="TVW25_001135"
     CDS             5155..5511
                     /locus_tag="TVW25_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1378770.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            5522..5800
                     /locus_tag="TVW25_001136"
     CDS             5522..5800
                     /locus_tag="TVW25_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378771.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            5797..6141
                     /locus_tag="TVW25_001137"
     CDS             5797..6141
                     /locus_tag="TVW25_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1378772.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            6145..6504
                     /locus_tag="TVW25_001138"
     CDS             6145..6504
                     /locus_tag="TVW25_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378773.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            6516..7115
                     /locus_tag="TVW25_001139"
     CDS             6516..7115
                     /locus_tag="TVW25_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1378774.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            7169..7624
                     /locus_tag="TVW25_001140"
     CDS             7169..7624
                     /locus_tag="TVW25_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378775.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            7699..7932
                     /locus_tag="TVW25_001141"
     CDS             7699..7932
                     /locus_tag="TVW25_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378776.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            7947..12104
                     /locus_tag="TVW25_001142"
     CDS             7947..12104
                     /locus_tag="TVW25_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1378777.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFNKAFSIIQNSVQKLSSAIPHPIKSAFTSATSAVVSFSSKITSAVSAAFNSVSSKA
                     STVADKISSSFGGRITSAVTNLATKLSTGLSNGFSRMSSSAATSLNGISQKFANTSSA
                     GERLKSTVMSIVQAFSLMAVAQKAMHALTGAIGGAVSRVDTMNRFPKTMALFGYSAEQ
                     SKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTSLALAFNNAMIGYGATTE
                     GAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAFGFGKNGVQDLKSALSDG
                     KITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHTAVVKGVAGMISAFDEAA
                     KANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWAVMNPASAISTIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQIEQLLNTAVTKGPGIIQ
                     GLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQLITSLVQGIGQNATNLI
                     SSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIPLIIQQAQQIIDSFGNSL
                     QANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAGIQLVAQLAVALIKGLPQ
                     IISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     VMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVNAQTGTMS
                     LQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     VNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSSVTSGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFD"
     gene            12116..12958
                     /locus_tag="TVW25_001143"
     CDS             12116..12958
                     /locus_tag="TVW25_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1378778.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            12968..14950
                     /locus_tag="TVW25_001144"
     CDS             12968..14950
                     /locus_tag="TVW25_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1378779.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            14950..16068
                     /locus_tag="TVW25_001145"
     CDS             14950..16068
                     /locus_tag="TVW25_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1378780.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            16083..17969
                     /locus_tag="TVW25_001146"
     CDS             16083..17969
                     /locus_tag="TVW25_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1378781.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            17981..18418
                     /locus_tag="TVW25_001147"
     CDS             17981..18418
                     /locus_tag="TVW25_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1378782.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            18415..19026
                     /locus_tag="TVW25_001148"
     CDS             18415..19026
                     /locus_tag="TVW25_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1378783.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            19038..19310
                     /locus_tag="TVW25_001149"
     CDS             19038..19310
                     /locus_tag="TVW25_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378784.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            19307..19534
                     /locus_tag="TVW25_001150"
     CDS             19307..19534
                     /locus_tag="TVW25_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1378785.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            19651..20985
                     /locus_tag="TVW25_001151"
     CDS             19651..20985
                     /locus_tag="TVW25_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1378786.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            21259..>21923
                     /gene="spei"
                     /locus_tag="TVW25_001152"
     CDS             21259..>21923
                     /gene="spei"
                     /locus_tag="TVW25_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL1378787.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKRVDIFTLEYSPPCNSNIKKNSYGGITLSDGNRIDKKN
                     IPVNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFNIYGYGDVKDFG
                     RSSRFQSGFEEGNIIFHLNSGERISYNLFDTGHGDRESMLKKYSDNKTAYSDQLHIDI
                     YLV"
BASE COUNT         7252 a         3883 c         4830 g         5958 t
ORIGIN      
        1 cacctagcat tccattaaaa tatccaggtc gttgagcaaa ttcaaattgg aggctatctg
       61 ccaattcgat gataatatct ttatattttt ctggatcaag taatattaaa acagtaatta
      121 aaccagcatt tcctgaatct acgtaaggag atccattgtt attttcaatt ggaaccattc
      181 tacccatttt agtagaaatt aatttagcaa atattttttg taaaccataa ttaagttcat
      241 catttgaaat ttttccaaca atatagttag tataaagttt acctgctaaa ccatcaattc
      301 catatctatt atatgaatca atccgatatt ttatatcatc tgaatcagac tgaactgccc
      361 cccaaaagtt agacataaaa tctaacaatt ggggggctat ttttatgtct aacttttggg
      421 gggcagttca ctattgacct tatgtcggtc agaaacaatg aggactacca caacgtcaaa
      481 ataaaaacag atttatcaat ttatggaaga gcctacgagc tgttaactgt tgagaaaata
      541 gatgacaaaa aaaccgaagt aaaactctac cagctcccgg ccgagcaaac ttttgttatc
      601 tatgatgata cataccagcg aaattcgttg atggccgttc atttctacga catagattac
      661 ggctcaggta aacgtaaaca gattatcaaa gcatatactt ccgacacaat ttatacctac
      721 gaagactata accttgaaac aaaaggtatg cgattaaaag attatgaagg acattttttt
      781 agaggtgtac cagtcaacga atacgctaat aacgaggagc gaacgggggc ttatgagtct
      841 gtacttgata atattgacgc ctatgattta tctcaatcag agcttgctaa ctttcaacaa
      901 gattcagtca atgcgttgct tgtaatagct ggtaatgctt acacaggagc tgatgagaat
      961 gactacttag atgatggccg attaaatcct aatggtcgtt tagcgatctc aattgggttt
     1021 aaaaaagccc aagtgttaat tttagacgat aatcctaatc caaatggcgt taaaccgcaa
     1081 gcgtactttc tcaaaaaaga gtatgatacc gccggtagcg aagcctacaa aaatagatta
     1141 gttgcagaca ttttgaggtt tacttttacg ccagatacac aagatatgaa attttcagga
     1201 gttcaatctg gtgaatcaat gaagtataag cttatggctt ctgacaacta tcgcgagaag
     1261 caagagaggt tgtttaaaaa aggattaatg cgacgcttac gcttagcagc taatatctgg
     1321 gccatcaaag ggaatgaagc aactacatat agccttgtaa atgatacgag tatagttttc
     1381 acacctaatc ttcctcaaaa cgataatgaa attgttacag ctgcacaaaa tctttatggc
     1441 attgttagcg atcagactat ctttgaaatc ttaaatactg tcacaggagt agatgctgaa
     1501 gcagagcttg aacgcttgaa agaagaagct gataaaaagc aatctttacc ggagcctaga
     1561 ttggtaggtg atgctagtgg tcaagaagaa ccaacggcag aaaagcctta attactggca
     1621 aaagcgtcaa aaagatattc taagttattt agacagaact gatttagatg tcttttcaga
     1681 actgcagaag ttatataatg aacaggcttt tgagttacaa aaggaattgt ttgattttta
     1741 tactaagtat tctgaagaga acaaaatgac ttatcaggat gtcgttaaaa aactacgtca
     1801 tgaagattta tcagattacg tagctaatgc taacaagtat cgtaaacaag ctgagaaaga
     1861 tcctgagctg ctaaaacgac ttaatgagca gtatgtatca gcaagagcta caaggatgga
     1921 tgcattaaat cttgagcttg tttatcgtgc ggggatacta aaaggtgtac ttgattcagc
     1981 atttgaaaat catttaaaaa aagttgcctc atatgcttat aaaaaagcaa tgggtggacg
     2041 gtcagggaca atcaatggtc cagttttaga agaactggtt agaaccccgt ttgatggtta
     2101 taactattca gaacagttgt ggggcaatac tgacaatctt gttaagaatc ttcaaaagag
     2161 attaaaacaa ggttttgttc gtggcgagca tcctagagcg atggccagag atttagctaa
     2221 gcgatttaat gttgctaatc acagggctga aacactaatc agaactgatg gaactatggt
     2281 gattaataat gctaccgcta ggcgctactt gaatgcagga cttaagtatt atcgtgattt
     2341 agttagactt gatgacagga caactgagat atgccgtaca attgctaaag aaaacaaaag
     2401 aaagctatta tctgagctaa agcctggaat taatgtagca ccctatcatt tcaactgcag
     2461 aacaactatt attcctgatg aagatgagct aagtattgaa gtagaaccaa ttgatgataa
     2521 aagcactaag tattttaagg atgtcacctc agattggata gatggaaatg agcataaacc
     2581 acaactgtca ctactaaatg agtacgtaaa aaatggcact ccttacaaag tagatggcca
     2641 tagtgtcgtt cttgatcatt cgaattatga atatagagtt gctaattggt tatccaaaaa
     2701 gacaggattg caagttgaca tggtgccaag agttaattcc cctgaacata tcaagactcc
     2761 tgattattta gttgatggag ctccttttga tctaaaagaa atcacaggtt cgggtaaaaa
     2821 cgtcattgat ggcaatctac gaaaagcaaa aaagcaggca actaatatca tttttgatat
     2881 aacaaaaacc cctttatcat ttgaagagat aatggggcaa ttagaacata tttatatgat
     2941 agatcgtagg ggtcttgata tatcaattat caaaaataaa gatgaggtat tagctgtatt
     3001 agaaaaagaa ggaggatgac ccaccgcctc cacagtaaac tgcttcatgg gcgttagacc
     3061 atcatccttc tttatctcaa ttatacatca ccctattaaa actatcaagg aggaaaatat
     3121 gtttatttgg caaatggtat tagtggcact aggtgtattg gtactcatat tgattgttgg
     3181 cattgcagca atagcggtta agtcaattat tgcagaattg aaaaaagaag gataaaacaa
     3241 tgaataagcg cattaagaaa aaacgtaaat tggaaacagc ggttgtgatg cttgttgcag
     3301 agaatgccat gcaagcagaa gctattaaaa atcaaaacaa acaaatcatg gagctaaaat
     3361 caatcgttca acgaaacgct ctggcaacaa acgaagagtt agcgactgtt aaagctgcta
     3421 ctttagataa ccaatcagtt atcaaggcaa ttggtgacac ggttgactat attaagaaaa
     3481 actacaaacg gaagtagggg aaataaagtt taaccgtgtc gaatttgacc tctttacaaa
     3541 tctaaaccaa agtcgtagca atacggcttt ttattgtgtc caaactttgt tgatgacact
     3601 aaaagctaca ctgtttcgtc gcaggacgta aagctagact atcggttggt ggcgtaacca
     3661 ctaggagaaa gttatggcag aagaaaatgt aacaacagag acaactgagc aagtcgacac
     3721 tcaaaaagaa gctgttgaac atcctaagca tgaatatgag cgaactttta ctcgcgcaga
     3781 catctcaaaa atgatggctg ctgaacgcac taaatgggaa tctgaacaat ccgcagctat
     3841 tgaaaaagct cgtacagaag gtgaacgttt ggccaagttg tcaaaagatg agcgcgctaa
     3901 agaggaggaa caaaaacgtc tagatgctat cgcagagcgt gaaaaagcag tagcagagcg
     3961 tgagatgcgc attgagacgc attccctgct tgtggagaaa ggattgccat tggattttat
     4021 tgatattgtt ttagccacta ctgcagaaga ggttaaggcc aatattgata atttacaaac
     4081 tatttttgat aaagctgttg aaaaacgtgt taacgatcgt ttaactcaga aaccgccacg
     4141 aactggaaat ggctcggtcg gtatgactaa ggctgacatc atggcgatag aggatgacga
     4201 cgaacgtatg cgtttaattg ctgagaatcg taacttattt taagagggga atattatggc
     4261 tgaaaaaaac ttaaacacta tggcggactt aggagatatt aaatcaattg attttgttaa
     4321 caagttttcc aaaaatatta atgatttact aaaattgcta ggggttactc gtcgtgaaac
     4381 attaactaac gatctaaaaa ttcagaccta taagtgggaa gtgactttag atcaaactga
     4441 tcctggagaa ggggaaacaa tccctctgtc taaggttact cgaactaaag ataaagacta
     4501 tacagtgaag tggttcaaga aacgtcgtgc aactacagct gaggcaattg ctcgccatgg
     4561 tgcagctcgt gctattactg aagcagataa gcgcattatg cgtgagcttc agaatggaat
     4621 taaggatgca ttctttacat tcctcaaaac aaaaccaaca aaagttaaag gcgttggcct
     4681 tcaaaaagcg ctgtctgcat catgggctaa gctagctact tttaatgagt ttgagggttc
     4741 cccgcttgtt tcttttgtct ctcctttaga cgtagctaac tatcttggag atactaaagt
     4801 aggtgcggat gcctctaatg tttttggaat gacattgctt aagaactttt tgggtatgca
     4861 aaatgtgatt gttatgccat ctgtgccaga gggtaaaatc tactcaacgg ctgtagaaaa
     4921 tctagttttt gcatctttaa atgttaaagg gggagacttg ggcggcttgt ttgctgattt
     4981 tactgatgag acaggtttaa ttgctgcagc tcgtaatcgt cagctttcta atcttaccta
     5041 tgaatctgtt ttctttgggg cgaatgtact gtttgctgaa attcctgaag gggttgtaga
     5101 ggcaacaatc gaagctgctg ctgtacccgg cattggtggt taaaggctat ttatatgggt
     5161 gataaacaac ttattgacga tatcaaactc tttataggta tttccaaggg tgatggtgcg
     5221 caagatgagc tcatcaccct tgctatatat gaaagtaaag agcgtgtgct agctaaactt
     5281 aatgaatact cagaaactga aatcaccaaa attcctgata gattgaggtt tattgtccgt
     5341 gatgttgcta ttaaacggtt taataggatt aattcagaag gagccgttga agatagcgaa
     5401 gaaggaaaga cttttaagtg ggacagttac cttaaagagt atgaatcaac actcagaagc
     5461 gctgctattg ggaaggtata ttcaggcaaa ggggtagcaa gatttattta ggagatacac
     5521 aatgatctat aaagatagag taatcttagt gtatgtcgat gaacaggacg attttctaga
     5581 taaaagaact gttgaaaaac ctagcgggaa aatcccctgt atggaaaata ctttcacaaa
     5641 atctgaacag atggggctat ttggtaaata tgatttgaat gcttttaagt tgcacttgca
     5701 aggccattac gacggcttta gcaagattat ctacaaggga aaatcgaggt tgataaaggg
     5761 actagcacac cataaaaata gcacggttat ttatgtatga gtcttattta tcggatgaga
     5821 ggcctagata ggtttttacg cagcgttgag cgcaagcaga agtcagtacg aatcgctgta
     5881 gataaagagc ttagtaaatc agctgctagg attgagagac aggctaaaat actagccccg
     5941 gttgacactg gatggctgag agctcaaatc tacagtgagc aacaacgact cttacactat
     6001 agagtggttt ctcctgcttt atattctatt tatcttgaat taggtactcg taaaatggaa
     6061 gcacaatcgt ttttagaccc tgccctgaga aaagaatggc ctgtgctaat ggctaatatc
     6121 aaaaaaatgt ttaagaggtg atgcatggat tactcactgg aaacactata tttaaaaaag
     6181 gtaaaaaata gattgggagt tttagacata ccaatctatt ttaaattgcc taaatcagac
     6241 gttttagagc cttttattgt tgtaggtaca aatatatcag acttgtcaaa aacagctcaa
     6301 actggagcag ttattgatga ttttagcctg aatatcgatg ctttcttacc tggcgatagt
     6361 cgtttggatg cagaagagat aaaatctcgc atgcttagac tgcttgggcg aaataaccaa
     6421 ataaaggctc agattttggt agataattca ataggacgag aagtctatag agttgctatc
     6481 aacattacag aaacactatt ttaaagggga cctaaatggc aaacacaaaa aaaggaacaa
     6541 ctattgaaat tacaacaggt aaaccgattg taggaaaaaa gattttttac tttatacaat
     6601 cagttgatgc accaaagaaa agtcaggctc tgttgccagc ctatcgtacc gatggtacta
     6661 caaccatggg tggtgaatac attgatgagc aaacccaaca aggtcgcgtt attgagaagg
     6721 ctacagatga acactctatt gatttgacaa cgtactttgt accgacagat ccatctgttg
     6781 ctgtcatcga ggaagctaag aaaacgggta aatctatcaa aatttgggaa gttattgccg
     6841 acgaaagcgt caaagaacaa atccaaattc ctgaatcgag tggtcccaag aaagatgttt
     6901 accctgctaa gtttgggtac gccaagattg acgaaatcga acgtggtact ggtatttcag
     6961 acttagtaga aatgtcctac accgctaaca ttgtaggggc cttacaagat ggtaaattcc
     7021 ctctcacgaa agaagaaatt gaaatgctag aaaatgtata cggctatcaa aatccgggtg
     7081 atactactgg cgactacgat aatatcacta agtagtacac aggggcggcg actgctgccc
     7141 cattttgatt taaaaaggag ataaaataat ggaatttaca gcagcgaaac gaaatatcga
     7201 tattaaattt gattttaaaa ctatgtttaa gatcaataat aaactaggaa caattaaccc
     7261 agaaacagga gagcgcaatg cagatggtgt tggtgctttg tttttcaata tcttagagcg
     7321 taatgaaagc gccattgttg accttgtgcg tttatctgcg ggaagcggaa aaaaagcgct
     7381 aactgaagat gaaattctag atgcaattgc agaagctgtt gatgaagaag gaacaacaga
     7441 agggttgttt gctgaaatag agaaagaaat ggttgattct ggttttttca gagcgaagat
     7501 tttgaaatat atcgaaaaca tggagaaatc agctcgctat ctcaaagcga aggacgatac
     7561 ggacgcaact caaatccaaa ttatcgaaga catgattgga agaatgagca acgcagtatc
     7621 ttagtaaatt gcgcacggtt agggctcaca gacattgata ctatctataa atgtactaag
     7681 tgggagctag aggctattat ggaggggctt gagtataagc aggttgctga gcgcgagaac
     7741 ctctctgaat tgtctctaaa acttagatat acattaaatg ctaaaaaggt tgatgtaggt
     7801 aagctcaaat atgataagca taggctaact atcaaaagat cgtatcaaaa agctagccgt
     7861 agccaagccg atagtgatag cagtattgtt gagagaatac aaatgcttaa taatcatttt
     7921 caaaatagat agataaggag gagtagatgc caggaacatt tgatggttct attttcgctg
     7981 atgttggtgc caacacaaag gactatgagc aggccatggc tcgtattgtt agtacgactc
     8041 agaatgcttt cagaaaagcc caagatacag cggttaacag tagtaataaa atggttcaaa
     8101 tcattggaca aatcatggcc caattagcga acaacggcga atcgctcgga aagagacttg
     8161 gttccgccta cgctactggt ttaaaactga gcattggtga aattcaacgt atagcagctt
     8221 ccattggcga aaaaattccc gaacccataa agaatggttt caataaagct ttttcaatta
     8281 tccaaaatag cgtacagaag ttatctagcg ccatccctca ccccataaaa tccgcattca
     8341 caagtgcaac aagtgcagta gttagctttt cgtctaagat cacaagtgcc gtctcagcag
     8401 ctttcaactc tgttagttct aaagcgagta ctgttgcaga taaaatcagt agtagttttg
     8461 ggggtagaat cacttcagcg gttactaatt tagcgactaa gttaagtaca ggtcttagca
     8521 atggttttag cagaatgtct agttctgcgg ctacttcctt gaatggaatc agccagaaat
     8581 tcgccaacac ctcttctgct ggagagagac tcaaaagtac agtgatgagc atcgtgcagg
     8641 cctttagttt aatggctgtt gctcaaaaag ctatgcacgc tcttactggg gcaataggcg
     8701 gggcggttag tcgggttgat accatgaacc gctttccgaa aacgatggca ctatttgggt
     8761 attctgctga acaatctaag gcatcaattg ataagttgtc aaaaggaatt gaaggtctgc
     8821 caactcccct agatagcgct gtgaaaagtg ctcagcagct cgccataacc acaggaagtt
     8881 tagataaagg aactagttta gccctcgcct tcaataatgc aatgatcggt tacggtgcaa
     8941 caactgaagg ggctgagcaa gcactcaggc agtttaacca gtcgttgggg tctggaaaaa
     9001 ttcaagctga agagtttaac tctgtatcag aagctgcgcc gggtttaatg tctaaaatgg
     9061 cggaagcctt cggttttggt aaaaatggcg tacaagattt aaaatcagcc ttatctgatg
     9121 gcaaaatcac tgcacaagag ttcgcagata aaatgattga gcttaacgat gcccaaggcg
     9181 gatttgcaga gatggcccaa tcatcggctg gtggaatccg aactgcgtgg aagaacgtac
     9241 ataccgccgt tgtaaaaggc gtagcaggta tgatttcagc ctttgatgaa gcggctaaag
     9301 ctaatggtat gaagaccatt gctgaaacac ttcttagtct gaagccagca ataaccagtg
     9361 tttttgatac gattaattct cttattccaa atgcagttgc agcattcgct aggctaaaac
     9421 agtctatcaa tattgacttt agcccattag gcgccagcgt taaagaggtg tttgctctta
     9481 ttaatattgt ttttggagat tttgcacata ctggtgaatt atcagagcag gcttttgata
     9541 atctaaaagc aaaaatcact tctttagctc ctaaagtcat tgccctttgg gcagtgatga
     9601 accccgctag cgctatatca acgataatgc ctttgctttc tctattcgga aaagttggtc
     9661 tagctttagg aagcttaggg acttctgtcg gggcgtttgg cggcataatt tctagtggga
     9721 tagctagtgc cagcggcgtt gttggtgcct ttgcggcaac tctaagcgga ttacctggcg
     9781 tttttgctac cgcagcaggg cgtgggctat ctgtgcttgg aactatgaca agcgcaatgt
     9841 ccagtcttgt gagtttagca ctggcggcca taggaccggc cgctattcta ggtcttgtgg
     9901 tggcaggact tggtttgatt aatagtcagt ttggcgcaca aatcgagcag ctacttaaca
     9961 ccgcagttac aaaaggtcct ggcattattc aaggccttgt aaaaggaatt acttctaaaa
    10021 taccagtttt gatagctagt ggcactcaat tgattgctaa atttgcaaat gctatcgcag
    10081 tgttattacc agttataatt caagctggcg ttcagctaat tacgagtctc gtccaaggta
    10141 ttggacaaaa tgcaacgaat ttaattagtt cagcaataaa aatcattggt agttttgtta
    10201 gttcaattgc gagtgcattg ccgcagctta tttctgttgg aatggagcta ttattaaatg
    10261 ttgtcaacgg catagttcaa aatatacctc ttattatcca gcaagcccag caaattattg
    10321 atagttttgg gaatagttta caggctaacc ttcctagtat tattagcaac ggtatagcta
    10381 ttttggtgaa tcttgtacag ggaattactc aaatgttgcc aactgttctg cagatagcta
    10441 ctcaagtcat tacgagtttt gtatctggaa ttgtacagtt tttaccgcag ttacttcaag
    10501 gtggcattca aatcattatt agccttgtgc aggggattat tcaaaatcta ccccagattg
    10561 cacaatctgc tgtacagatt atacagtctt tagcttctgg actgacgcaa gctctacctc
    10621 agattatcgc agcaggcatt cagcttgttg cgcaactagc cgtagccttg ataaaggggc
    10681 ttccacagat tatttctgcg ggtattcaat taattatggg gctcggtaaa gccatgttag
    10741 gggctatccc aaacgctctt tcaggagttt gggaaggtat taagagcgga ttcagttcga
    10801 tgtgggacca aatcacaggt aagagttcca caagtacagc taaagtctct gcggacgcca
    10861 cggtcatggc catgaatgtt gggatgcaaa cgacagctat ggctaatcaa gctaatacag
    10921 atacgacatc tatgcttaat agcattagtc aaaatacaga gcttgctaat ataaacgcta
    10981 catcaaatgc cacacagatg gctaataacg ttaatgctca gacaggaacg atgagtcttc
    11041 aggggttgaa tgattcgatg tctcttgcga gtggcattag cactaatatg tctgtcgcta
    11101 atataaacgc tactactcag gctcgagaaa tggcttcagg ggttaatggt gcgacttctt
    11161 caatgaatct agacgccatt aatcatacgc tcagcttagc tagtggtgtt ggtgcgaaca
    11221 tgggagctgc tagcacaggt gcaacttctc aggcgcaagc tatgagctca ggggtgagta
    11281 acagcctggc atcaatgcag tcaaactcaa ctaaagcagc ctctggtctg tctaatagtg
    11341 tgacaagcga aatgtcttct gcagcaacct ctgcaacctc aagcgttaat aggttgtcct
    11401 cggcggtcga gtctggcttc aataaggcga agacttcagc aacaacctca atgaatggga
    11461 tagccaatgc ggttaaaaca ggatttagta gcattaacag tactgcaaag caatctatgg
    11521 caaaccttgt aagttcagtg acttctggga tgtctcgtgc aaccgcggtg tctaataatg
    11581 cttgtcagaa gatcctctca atattcaggg ctttggcagg gcagatgtct tctgcaggag
    11641 cttatgcagg tcaaggtttt gctaatggtc tagctagtag cgcaggcaca atctacgcaa
    11701 tagctaacag cattgccgct aatgtagcag caacaattag acgcgcttta gatattcact
    11761 caccatctcg tgtcactaaa acactaggtg catttactgg agaggggttt gccctcggta
    11821 tggcagagtg gataggtgag atcaatagcc taggtaaagc atacgcaaca gcagttactg
    11881 atcaaaactg gggggtaaat agtactgttt caacatctgc taaagttaat aatagtggaa
    11941 tcaatacctc tcttgataat cttagcgaag aggttaggca gtctcaattg tcagagccta
    12001 tctttgaagt gcataatgag attgttggag ataaaattta cacggctgtt aaagaaaaag
    12061 aatcaagaga gcaatctaaa gattcttatt ttgtttttga ctagaaggga gtattttgga
    12121 tttattaata gaaaaagaga gtcaggcaac taggttgtct gactttggta tttataatat
    12181 tgctattgaa gatagcgctc ctttactatc tgtatcacac cgagcagtca aaggaaggag
    12241 tggttacatc tacgatgggg ctacttttac gactaaaacg cttaaggtca aaggaagagt
    12301 gacggtaagc aacgtggaaa gacttttgga caaacaggac gaactaaacg ctctgcttgt
    12361 tgttgacgaa cctttctacg tgactaagat gtaccctgaa aactcagatc tatttaactt
    12421 tgagcttcca ggggaaagca caggagacct gcaacttatt ggctctcctc ataaaccttg
    12481 gaaatataga tttaaagtca tcttagacga cactatcgct tatgaattta taggaaaaac
    12541 cagtcaagga ctaaaatata atctttcctt cgcgctaaga actgctgaat tacctttcgg
    12601 tgagacaaag ccaaaggaca taactctatc agggggcagt tttgcctatg caggaaccgc
    12661 taaagcaagt cagctagagt ggccttttat tatagagctt actccttctg gaggtcagac
    12721 taatttttat attgaaattg atggcaggcg ctttgagttt aagcagaata gccagctaca
    12781 aaatagtgat aaattacttt tgacaggcat agctaccaca ctaaacggaa attatgtcaa
    12841 tgctaaaacg aactatgagt attttatctt caatcctaat cctaacaaga gaattactta
    12901 caaaacggat tttcttggca cgattaggat tttaaatttt gtagagttgt ataaataggg
    12961 aggtctaatg attacttttt tggatcatcg tgacattgag tatggggtca ttagtgtcat
    13021 taggcatact aatgctgtta atggtgagcg ctcagtgagc ggggaaattt atacaaacag
    13081 tgatgtcctc aataatatcg atagagggtg gcgacttaga tttgaagatg agtattacgt
    13141 tgttatttac gcaaagcctg ttgatgttgg tcaaaaaacg caagtttcgt ttgatgccat
    13201 acaccaattt ttttgggact tcagcaagag tagtatctat gagggtctcg gagatgggtc
    13261 tcataccatt gatacctatc tagagacagt atttaaaggt agtgggtacc gctataagct
    13321 agaagtaggt gtgaacgcat ttagaaaaca atcttttaat tataagtcca ggttagattt
    13381 attcaatgag attattaaag cgaccggact tgaattttca gtcagcggga aagttgttcg
    13441 gctattaaaa aacataggta ctgatctgtc aacagtggta cgaaaaaatt tcaacatgaa
    13501 tgaccttacc attgaaaaga atattgatag ctttattacc tatcagaaag gctttggtgc
    13561 atggaccgac ccagaggacc actctaaggg gagacttgag gcggaatacg aaagtcctct
    13621 tgccaaggag tacggtcgac ttgaaggggc gcctctgacg gatgagcgct tcacggtggc
    13681 agataatcta aaagaagctt taaaaagtaa tgttgaaaat tcatataaga tatcagtaaa
    13741 aattgatatg gaagatttaa cgagagctgg gtatagatgt gagaggccgg ttgctggtga
    13801 ctacattatg gcgataaatg agactttagg ttttcaagag cgtatacgga tagtttcttt
    13861 tacaagctac tacgacgcaa ctggagcttt agtaaaacat gaagtcactt gtaatgatat
    13921 cggatctgtg aaaaaacaaa gcgtaggaag tctgtctata aacagtagaa tcaatcagat
    13981 agatgcagat attgcttctg caattgaagt agcaacacaa gcactagtat ctgctgacgg
    14041 gaaaaatact gtttacggtg gcacagaaat gcccaaagat gaaccaaaag gaaccttaaa
    14101 aaaaggagac atattattcc taaaagttgg cgatactact agaatgtatt tctggaatgg
    14161 tgctgagtgg gaagaacctg aggttgtgaa cgacccagaa cgatggcgtg aagacctcga
    14221 aaaacaaatc tctgaggcga tcgaaaaagc caaaaaagca caggaagaaa tcaaccaacg
    14281 caccgataaa gagcttgaag aatttagagc cgccctcaaa aacctagcgt taccagagga
    14341 agcgattaaa aaaatcacag aggctataaa agttgatgac atcccgtcta ttaaacaaag
    14401 ctttgatgac ctcaaaaata gagtgagtga gacaagcgaa gaatctcgtt taactgccga
    14461 aattttaggg aacaacggta agacacgcta caacaaaaat ttgctggtcg gtgagcctaa
    14521 tcgtgttaaa aaaattgatg aggattttat cgaggtagaa gctaatgatg gtggtttcaa
    14581 gcgtggcgag acttacacaa tcagctttag tcagacatgt gagccgctca aaaaagtggc
    14641 tatcacgctg atccaagcta ataataaggg agttaaactg gtactgacac ctactaaggc
    14701 aaaaatggag cctgagactt ttactctaat taaggacaca gaggtcatca acgtctatcc
    14761 tttgagctac tcagtcactt taagtggtga ctggtacaaa tctaagcaag tagatttaaa
    14821 tgcgtcggag gtgcgaaata tggctctggg gatgagttat agagatgtgg ttgatggtaa
    14881 taatgctgat ttaattttgg actgggcgga aaacccagat attatttttg acggaaacgg
    14941 aggtatttaa tgtcaaaaga agttgcatca gcaaggatac agcatagagg catgaccaaa
    15001 caagagtggg aatcaagctc cgatatctta atggagcgag aaattggaat tgatatgact
    15061 acgggttacc caaaagttgg tgatggcaaa aataagttca aggacttaaa agacttgcgc
    15121 ggccctatgg gacctcaagg tccttcagga gaaagaggcc taactggccc aattggtcct
    15181 cggggccctg ctggcaagcc tggaacgaca gattataatc aactccaaaa taaaccaaat
    15241 ctagatgcgt ttgcacaaaa aaaagaaact aatagtaaaa tcaccaaatt agaatcaagc
    15301 aaagcagata aaagcgctgt ttactcaaaa gcagagtcaa aaatagagct agacaaaaaa
    15361 ttgagtttga caggcggcat agtgacagga caactacagt ttaaacctaa taaaagtggt
    15421 attaaaccct catcttccgt aggaggagcg attaacattg atatgtctaa atcggaaggt
    15481 gctggtgttg ttgtctattc taacaatgat accagtgatg ggccgttaat gagcttgcgg
    15541 acgggtaaag agaccttcaa taaatcagcg ctttttgtcg attataaggg aacaacaaat
    15601 gccgttaata ttgtgatgcg tcagccaacc acccccaatt tttcatcggc gcttaatatt
    15661 actagcgaca atgaaaatgg tagtgcaatg cagctacgag ggtcagaaaa agcgctagga
    15721 acgctcaaaa tcacacacga aaacccaaac gttgaggcaa aatacgatga aaacgctaca
    15781 gcgttatcta ttgatatcgt taaaaaacag aaaggcggaa aaggtactgc tgctcaagga
    15841 atctacatta actcaacatc aggcacgaca gggaagttgc ttaggattag aaaccttagt
    15901 gatgataagt tctacgtcaa gtctgacggt ggtttttatg ccaaggaaac ttcgcagatt
    15961 gatggcaacc tgaaactcaa ggaccccaca gcgaatgatc atgcggcaac caaagcttat
    16021 gtagataaag caatttctga gttaaaaaaa ctcatactaa aaaaatagat taaggaggat
    16081 aaatgagcag agacccaaca cttattttag acgagtcaaa cctcgttatt ggtaaggatg
    16141 gacgtgtgca ttacacattt accgcagagg acgacaaccc aaaagtcaga ctagctagca
    16201 agtgtctagg cacagcgcat tttaatcagc tcatgattga gcgaggagac caagctacta
    16261 gctatgttgc gccagtagta gttgagggta caggtaatcc gactggacta tttaaagacc
    16321 tcaaagagat tagcctagag ctgacagata ctgctaattc ccagctttgg tcaaaaatca
    16381 agctgactaa ccgtggtatg ttgcaggaat actacgacgg taagatcaag accgagatag
    16441 tcaactccgc cagaggtgtc gctacacgta tcagcgagga tactgataaa aagctagcgc
    16501 tcatcaatga caccattgat ggtatcaggc gtgagtatcg agatgctgat aggaagctat
    16561 ccgcaagcta tcaggcaggc atcgaggggc taaaagccac aatggccaat gataaaatcg
    16621 gtttacaagc tgagattaaa gcctcagcac aagggctatc gcaaaagtat gatgatgagt
    16681 tgcgcaagct atcggctaag atcacaacaa cctcaagcgg cactacagag gcctacgaga
    16741 gtaagcttgc gggcttacgt gctgagttta ctcgctcaaa tcaaggcacg aggacagagc
    16801 tcgagtcaca aattagcggg ctaagagcgg tacagcagtc aacagctagc caaatctctc
    16861 aagagattag agaccgtgaa ggtgctgtca gtcgtgtgca gcagagtttg gagagttacc
    16921 aaaggcggat gcaggacgca gaagaaaact atagtagctt gacccatacg gttagagggc
    16981 tacagagcga cgttggatct ccgactggta aaatccaatc gcgccttact caactagcag
    17041 gacaaattga gcagcgggtt actagagatg gtgtcatgag tattattagt ggcgctggag
    17101 acagcattaa attagctatc caaaaggctg gcggcattaa tgccaaaatg tctggtaatg
    17161 agattatctc agcaattaac ctcaactcct acggagtaac aatcgcaggt aaacacatcg
    17221 ctctcgatgg caatacgact gtcaacggca cctttaccac aaagatagca gaggctatca
    17281 agattagggc tgatcagatt attgcaggca cgattgacgc tgctaggatt agagtgatta
    17341 accttaacgc aagtagtatc gttggtttag acgctaactt tatcaaagct aaaattggct
    17401 atgctatcac tgatttgctc gagggtaagg tcattaaggc tcgtaatgga gcgatgctta
    17461 tcgacttaaa tacagctaag atggacttta atagcgatgc cacaattaat tttaatagca
    17521 aaaacaatgc cttagtacgt aaagatggca cacatactgc ctttgtacat tttagtaatg
    17581 cgacgcccaa aggttataca gggtcagcgt tgtatgcatc gatcgggata acctcatctg
    17641 gtgacggtgt taactcggct tcttccggtc gttttgcagg gctaaggtca tttaggtacg
    17701 ctacgggata taatcatact gctgcagtcg accaaaccga gctatacggt gataatgtct
    17761 tgattgcaga tgactttagc atcaatcgag gatttaaatt tagaccagac aagatgcaaa
    17821 aaatgcttga catgaacgac ttgtatgcgg ctgtagtagc cttaggccgc tgttgggggc
    17881 acttggctaa cgtcggctgg aatactgctc atagcaattt tacaagtgcg gtcactaacg
    17941 agttaaataa tcatatcaac aaaatttaat aggagaaaca atggatttaa cgcttaaaaa
    18001 caaagattta aacacactat atagtgtact agacaaaatc aaagtcacga acatgcgagc
    18061 aaaccgcgga cgtgctaagc tactcgcaaa agtagtcgat aaattcaaag agtacgccaa
    18121 ggatgagggt gaccttattg atctgtatgc tcaaaaagac aaagatggca agtttgtcat
    18181 tgatgagcac aaaaacatca agctagcaga ccccgctaaa ctcgacgagt tcaacggcct
    18241 actcaacgag ctagctgatg aagaaattgt gattaaaggg ggtgagtact ccaagcgatt
    18301 tattgacttt ttaaactttt tagaagagtg tgaagatgaa tttacatcat ctgaaatcat
    18361 tcttatcgac aacattttgg aacaatttga agaaagtaaa aaaggagaaa aaccatgaga
    18421 aattggaaag tgacaggaaa atacccacaa tttgacagca caggagcagt cgcaagcaca
    18481 catattatta tcactgctga ggatggctca gtcatctctc aaccaatcaa gcagggctta
    18541 acttcaacta atgacacaga gattatcaaa gctactttgg aagaatttaa aaaatctgaa
    18601 tacgtcgaaa tcgctatggg cgaagccgtg caaaaagtag acgaccttga aaaaatctca
    18661 caggaaaccg ctaagaccgc taaaacagcc caaacagccg caggattagc taaggtgtcc
    18721 gcagagcgta cacagcggat gattaacttg caaaccatcc acgtattgac aagtggtggg
    18781 aaagttgaac ccgatatcta caaaggtatg ttagagctta ttgaacctgc taaacaaggc
    18841 gagtatcagg cttatgacgt gtttactgtt gtagatgagt cgcacgaaga tcaagcggga
    18901 gaaggtaatc ttgtctttgt acacgttaac gagccgttta cttatgacaa acagacgctt
    18961 aaagagctag aggaagagga taaagtcaca gtcattaagt atgcggactt agttaagcag
    19021 gattagcgag gtaagctatg gcaacagagt tgatatttgg tcttggtggc tttattttag
    19081 ctatcgtcac gacttacaat atttttaatg caaaatccat caagcatgcg acagatatta
    19141 ctttgttgca gtctgaagta gagcatttaa aaattgttac acgccaaaat gctcggcgtc
    19201 ttgaggagca tgatgagcaa aacaaaacgc tcatcacaat gacagagcaa attaaaaacc
    19261 tcaatcgtga ggtaagagaa cttaaagata ttatgagagg tgaagcatga tcaatttaaa
    19321 attacgacta caaaacaaag taaccttgat ggctatttta ggagctatct ttttactggc
    19381 acagcaatta ggtattaaac taccatcaaa catcgcggat attgcaaaca cagctgtaac
    19441 gcttttggta ttgctcggtg ttgtcacaga tccaaccacg aaaggcctgt cagacagtga
    19501 gcaagctttg acttaccacg aaccaaaaca ataggagggg acatgcgggc aatcacacga
    19561 ttagcattag ttatagcaat agcaatactg tatgtgccat tatctgttgt tgctttgatt
    19621 ttaagcccat ttttagataa ggagggataa atggctacat atcaggaata taaaagtcgt
    19681 tcaaatggca atgcttacga tattgatgga tcgcttggtg cgcaatgttg ggatggctac
    19741 gcagactact gtaagtatct aggactgcca tacgcaaact gtacaaatac aggatatgca
    19801 agggatatat gggaacaacg tcacaaaaat ggtattttaa actactttga cgaagtagag
    19861 actatgcaag ctggagatgt cgcaattttt atggtagttg caggtgttac accgtatagc
    19921 catgtggcta tttttgatag tgatgcaggt agtggatacg gatggttttt aggtcaaaac
    19981 cagggtggag caaacggagc atataattta gtaaaaatac catattcaac gacttatcct
    20041 actgcattta gaccaaaagt ttttaaaaat gcagttactg ttataggtaa tataggacta
    20101 aataaaggcg attattttat tgatgtatca gcttatcaac aagcagactt aaccgctact
    20161 tgtcagcaag ctggcactac taaaacgatt atcaaagtat ccgagtcact cgcttggctg
    20221 tctgataggc atcagcaaca agctaatact agtgacccta ttggttatta tcactttgga
    20281 cgatttggag gagatagcaa cttagcgcaa cgagaagcag atttatttct gtccaattta
    20341 ccaaccaaaa aagtctctta cttagtcatt gattatgaag actctgcaag tgccgacaaa
    20401 gaagctaaca ctaatgcagt tattgcgttt atggataaaa ttgcaaacgc tggatataag
    20461 cctgtttatt acagctataa accatttacg cttaataata ttgattatca gcaaattatc
    20521 gctaagtacc caaacagcat ttggatagct ggttatccag actacgaagt acgaacagag
    20581 ccactttggg agttcttccc ttcaatggat ggtgtgcgct ggtggcagtt cacaagtgta
    20641 ggagtagcag gtggtttaga taaaaatatt gtattattag cagatgatag tagcaaagtg
    20701 gatataccta agattgacaa accacaaagc cagcttactt ttaatcaaaa gctagatact
    20761 aacactaaat tagacaactc gaatgtacct tactacgaag caacccttag cacagactat
    20821 tatgtagagt ctaagccaaa cgcaagtagc gctgataaag aatttatcaa ggcaggaact
    20881 cgtgtaagag tctatgaaaa agtgaatgga tggtcacgta ttaacgcttc tcagtctgac
    20941 cagtgggtcg aagataagta tttatctaat gcaacacaag tataaaatag gaggtaaagc
    21001 tcctttagat aagacaaatg ccctcgcttt tgcgggggct gtttttgtta taaagatttt
    21061 aattgttatt taagcatttt cgttgatttt tttctttttt gtgctaaaat attttgtgat
    21121 ttcttattat taaagaagaa tagggtacac ttataagtga gaaaaattgt aaatgttaat
    21181 tttaaaaagt ttttaacttc atcttttcta ttgtgggtat ttatatcagc tataattcca
    21241 acgtgttacg cgtatgagat gagtagtgtg ggagttatta atttaaggaa tttatactct
    21301 acatatgatc caacagaagt aaaaggaaaa ataaatgaag gtccgccatt ttcaggtagt
    21361 ttgttctaca aaaatattcc ttatggcaat agttcgattg aattaaaagt agaacttaat
    21421 agcgtagaaa aagctaaatt tttttctggt aaaagggtgg atatatttac tttggagtat
    21481 tctcctccct gtaactctaa tataaaaaag aattcatatg gaggtattac tttaagcgac
    21541 ggtaatagaa ttgataaaaa aaatatacct gttaatattt tcatagacgg cgttcaacaa
    21601 aaatatagct atacagatat aagtacagtg agtactgata agaaagaggt tactattcag
    21661 gaacttgatg tgaaatcaag atattatctt caaaaacatt ttaatatata cggatacggt
    21721 gatgttaaag attttggccg ctcctctaga tttcaatctg gctttgagga aggaaatatt
    21781 atttttcatt tgaatagtgg agagagaatt tcttataatc tttttgatac aggacatggt
    21841 gacagagaga gtatgctaaa aaaatacagt gataataaga ccgcttattc tgatcaactt
    21901 catattgata tatacttagt taa
//
LOCUS       DARYVE010000032        21888 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYVE010000032 DARYVE010000000
VERSION     DARYVE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21888
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            40..890
                     /locus_tag="TVW25_001153"
                     /pseudo
     CDS             40..890
                     /locus_tag="TVW25_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1226..1516
                     /locus_tag="TVW25_001154"
     CDS             1226..1516
                     /locus_tag="TVW25_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1378788.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            1530..2669
                     /locus_tag="TVW25_001155"
     CDS             1530..2669
                     /locus_tag="TVW25_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378789.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            2666..3148
                     /locus_tag="TVW25_001156"
     CDS             2666..3148
                     /locus_tag="TVW25_001156"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1378790.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3145..3732
                     /locus_tag="TVW25_001157"
     CDS             3145..3732
                     /locus_tag="TVW25_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1378791.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            3729..4211
                     /locus_tag="TVW25_001158"
     CDS             3729..4211
                     /locus_tag="TVW25_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378792.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4236..4751
                     /locus_tag="TVW25_001159"
     CDS             4236..4751
                     /locus_tag="TVW25_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378793.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            5385..7019
                     /locus_tag="TVW25_001160"
     CDS             5385..7019
                     /locus_tag="TVW25_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378794.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7160..8053)
                     /locus_tag="TVW25_001161"
     CDS             complement(7160..8053)
                     /locus_tag="TVW25_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1378795.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8037..8228)
                     /locus_tag="TVW25_001162"
     CDS             complement(8037..8228)
                     /locus_tag="TVW25_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378796.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            8463..10217
                     /locus_tag="TVW25_001163"
     CDS             8463..10217
                     /locus_tag="TVW25_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1378797.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            10358..10738
                     /locus_tag="TVW25_001164"
     CDS             10358..10738
                     /locus_tag="TVW25_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1378798.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            10776..13109
                     /locus_tag="TVW25_001165"
     CDS             10776..13109
                     /locus_tag="TVW25_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1378799.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13158..13310
                     /gene="rpmG"
                     /locus_tag="TVW25_001166"
     CDS             13158..13310
                     /gene="rpmG"
                     /locus_tag="TVW25_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1378800.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            13322..13498
                     /gene="secE"
                     /locus_tag="TVW25_001167"
     CDS             13322..13498
                     /gene="secE"
                     /locus_tag="TVW25_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1378801.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            13889..14434
                     /gene="nusG"
                     /locus_tag="TVW25_001168"
     CDS             13889..14434
                     /gene="nusG"
                     /locus_tag="TVW25_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1378802.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
     gene            15477..16994
                     /locus_tag="TVW25_001169"
     CDS             15477..16994
                     /locus_tag="TVW25_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1378803.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            17276..18139
                     /locus_tag="TVW25_001170"
                     /pseudo
     CDS             17276..18139
                     /locus_tag="TVW25_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            18728..21229
                     /locus_tag="TVW25_001171"
     CDS             18728..21229
                     /locus_tag="TVW25_001171"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1378804.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            21416..>21888
                     /locus_tag="TVW25_001172"
     CDS             21416..>21888
                     /locus_tag="TVW25_001172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378805.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGIND"
BASE COUNT         6424 a         3994 c         4884 g         6586 t
ORIGIN      
        1 taattatgtt aaattagaac tatgtgtaga gagagtataa tgaatagtac agatttgatg
       61 agactgggag agctttataa ggagcttcgt attgctcgtg gacttaggct aaaggacgtt
      121 gctagagaca atttatcagt ttcacagcta tctaagtttg aaaatggcca gagcatgctg
      181 gcagctgaca aactactatt agctatttca ggaatccata tgacattcgc tgaatttggt
      241 catgctgtaa atgggtataa agtcagcgat ttttttcagt taggcaccaa ggttgccgag
      301 ctacaaacag catcagatat agatggattg aaggagcttc tgagccaata taagggtgat
      361 gacatttttt ctgtttataa tagattaaat gaattaatca ttaaaagtgc tatctactca
      421 cttgatccaa atgttaaaat tgaagaatca gacaagcaat tgttgacaga atacctttat
      481 agtattgaag agtggacgga gtatgagcta tacatttttg gcggttgttt ggctatttta
      541 tctgatgagg atatgatttt tttgggaaaa gcatttatcg aacgagataa gattttcctt
      601 tctcttccac aacatagaaa ggcagctcac atcactctct taaatattat catgacaagg
      661 cagcttttta tgttgatttt tttattaaaa agctggagga gttgattatc tatcaagata
      721 tgttcactat agtgagctta aattttttta agaaaatata tacctactta aatgaagaaa
      781 gtaagcataa gagcgacatt gaagattata ttaatcttgt taaacagctt ggcaaccctc
      841 agtttgccca aattctacat cggacgctat cagtgattct agatagttaa tactaaaaaa
      901 gtagcccaat cgtttggtgg ctacagtggc caaggccacc aaatagacaa aagggctaat
      961 aagaaaataa aagcttttcg cataatatct cacctccttg ataaggatat tatacaaagg
     1021 ggaagcttca atctcaaaca ttcgcaaata tgaaaatatt aacaaaagca tcatcatatt
     1081 tgcgaatatc gagaatatga taattgtcgt gatataatta ctgtgttaat gatttagcta
     1141 ggcattaata aatctaaata tagactacag gcaggtcgct cgttatacta gtttgagggc
     1201 caatggtctg ggtaggagga agcgtatggc gacattagag cgacatcata aaatgttatt
     1261 attgtcaatg gcattagggg cagcgagctg gttagcactc ggattgatta gcttgccaaa
     1321 tcttgcaggt gctttaggaa taagtactgc taatgccaat actacagtta atttgttgag
     1381 tgcttatagt acagtttcta gcgttgttgc aatcgttggt gctgttacgg gtgtagggtc
     1441 tattggagct ggaattgcag ctaccgtttt ataccttatc aaacaaaaag gaaaggctgc
     1501 tgctgctctc tggtagttaa ttgtctgata tgaagcatgt tttcaaatat cataaaggcg
     1561 acattttagg gtatctcaat attgttgggt ttaccctttt gttttatggc tcagtgatag
     1621 gtatgataat gttcagggat tatttgacct atgatggagc tggttctcta atatcgacct
     1681 ttattctggt atcaggaacc tatcattctg tgaaatcaac atttccatat gaagggaagc
     1741 gtcatccaac ttttatatta acaccctatt atctatttaa gcatctattg ctttcagtta
     1801 caaaggttta tgctttccag atccgagtgg ttactatagg aatcatctgt ttagcaatag
     1861 cctttccgga gcagcttgtt tggatagcct tgtctgtgct agcagtattt atatattggc
     1921 tatcgcttcc gctagtagcc atttttcgag tagctggacg actcctgaat cttctcatga
     1981 tttatggtat gtatcttaat caggagctgc tggtcattgc ttgtctttgt ttaaatgtgg
     2041 ttattcttgt gcttagtgtt acgattaatg tacattatcc ctaccaatgg ctggcggtga
     2101 gagctaggaa ggaagaaaaa acaattacct tgttaaagct tgttatcaat acgataacag
     2161 atcatttagc tttaatggtt ctgtttagta ttttctgtat agctgtgacc tatttcacgc
     2221 aaaggctgct gctaagtttt gattattcta gctttagcat accagttttt ttcttatctg
     2281 cttctaccta tatcgcgtta ctagaggtta tggtcggtaa aaatattaag gagcttgagt
     2341 tagaccgggg cttggctgtt ttacagtttc tgaataggga tatcagtgtt tacaaagctt
     2401 atcgcaacag ccaattcttg ctttctgctc acatcttagc tgttattcat acaggatgtg
     2461 ccataggctt actaccattt ttactaaatg gtcaagctgc tctttttctg tctaacctag
     2521 tgatgatccc cttcatctac tttatatcat tttgctattt cgtgaaatca ctaaaaatag
     2581 ttgctggtga tttgtcagtg tttaggtggg ttattctggt tttgtatttt atactagtgg
     2641 tcattgcaat ggtaggtagt cgtttatgat aatgaggaaa tttttaagat attatatcag
     2701 ttttattatt ttctcaatag caattgggat tttaatcggt ttgctgatca ccagtgatac
     2761 tgtcatatta tctaagccag agcggggctg ggattttact ctggaggttt tgaagaataa
     2821 tagcaataat tttttgtcct atattttcct cttctttttg tccccagcct tgcaattgat
     2881 tgatttggta tcagttgtta tacaaattac tctaggaatg aggaagtctg gatttctaat
     2941 aactgccttg ggtttgtttc cgcatggttt gctggagatc cctaattttc tcttttatca
     3001 aggcttgagt caatatatgc tatggactgt tttgactgaa aaaagcatga cgtccttctt
     3061 agaaagagaa agaagatatg taaggtacta tcttatatcg tattatgttt tgttaattgc
     3121 tggtattatg gaagggttac tcggatgaaa atagtaaatg aaagcaagtc attttcaaac
     3181 agaaaaatct taaatcacat atcctttgac tttagtaaag ggctgtataa ggttgaaggg
     3241 aataatggta gtggtaaaac cacttttttg cgcttgttag caggcttaga acggtttgat
     3301 agcggccatc gcttacagca taagggagat attctatatc ttgatactaa tgctatcggt
     3361 gtagttccct taactattga agacaatctg acattattat ggaaaacctt taatgcctct
     3421 cctgatgagg agaccttgtc tgtgattaat cagttctttg gagaacggtt actagatcat
     3481 tatctgacgg cttctgtagg aacaaaggct aaggtgggct tatccttgct ttttgtaaag
     3541 gattgggatt atattttcat agacgaagcc ctatcaacgc ttgatgggtt tagtcttgat
     3601 atggttgcag gaagattatt agcattaaaa gaaaaggcta ctgtttttta cgtttctcat
     3661 aatctatcac accagcagct attgtcagaa tcacaggtga tttatcttaa tggaaaagga
     3721 gaaatctatt gaaaggtaat ccttttaatc gtaatctttc ttggttaata gcctatgtgc
     3781 tattactttc ttgttatgta ttcatattag tagatggtgg ttttttaaaa aacagcgttc
     3841 aagaattgga agtcctgctc ggccaaacat cactagctat aaagctgttt ttgatggtga
     3901 tatcaatagc ttttagcatc atatctttac tggttgagta ttttttaagc aaatttttag
     3961 tgctgctttt tattgaagct ggcatcgttt ctttaaatga tgttcttact gctaaatcag
     4021 tgactttagt gatccattta tctgctttgc tattgaagct atctccctct ccactttttc
     4081 agtttgtagt gaatgcttta gggattgtga tcatgtatgg attgagtatc aagagacaag
     4141 gaaataggac aactgctctt ttgttttgtt taccctttac actggatatt ctagcaacat
     4201 tgttgcttta gtgattttga gttggaggaa aagtaatgaa aaaaatctta tatttatcag
     4261 tacttttagg aacgtcaatt ctagcaacat tgattaaaat ttataacact ttttttgcaa
     4321 agctaaaggc ttcatcaggt cattcaactg ggaatataga gattgatgcc cttttatctg
     4381 agtctagact agtgttggaa aggcagcatg ccttcacaac aaatggaatc aacaagctat
     4441 tcgttatgat gatgagtcta atgctgttat tagccttata ctatctgata aaaaaggatt
     4501 tgaaggccgt ctatagttat ttgctttacc tggtgttaac cttggttcat gcaatttata
     4561 gcttcttttc gttaagtccc ttggcaaagc tttattctga tgatatgctg ggggctacaa
     4621 tccagacggg agagaaagct aaattgattt tttcagtggt tctttttctt ctttatctgc
     4681 ttattgttgt ggccaataat agagtaaaat ctagtgtaga acccgcttca tctattggga
     4741 tagatgtgta atacctttca tattatgacc tttaaagcct tttagcttct ctaattttca
     4801 gagtaactag gaggctgttt gtgacgctct gagcgttttt tcgtttctat caaagtttag
     4861 ctgcgttaat gctatctatt tccgtagctg agatacaaga tattataata tgtgttgtca
     4921 taccataaaa acaccttaca ggatatttta tgatcaatcc tccttgaatt aagctttctt
     4981 taagcaaggg tgtgtatact agccgtaatc ctaaataatt ggttacctaa tgataactaa
     5041 ttttttcata acctccttcc taaaaacgat gtcagggcag tcaggattga ttgctgttat
     5101 ggcatcgttt ttgttgtact ttgatagggg atctagctgt atgttaaata gcctatcagg
     5161 attgagtggc gaagatgatc aggagtctct tggctctagg ttatgctgct gtttcatgag
     5221 aaacagctct tgatgatcaa tttaggtagt attagtggtg gtcatcttag ccttttaggc
     5281 tttgagctgc tttatgtttg ctcattttta atatgttagt gtttacacaa ataattctca
     5341 ttttttgata taatagaaaa ggtaaggaag ggtaggagat aaggatgaca agattttttc
     5401 aaaaaaaaca ggccaaaagc ttagccattg gttttgtgag cttgtttgct gtgctcattg
     5461 ggtatggagc ttttcactat tctaaggcca gtcgtatcaa tgcctatcta caagcaaggt
     5521 catcaggctc tgggcaggtg cttgaaaata tcaaggaata cctcgtgtgg gcagatacca
     5581 atgagcagct gaccaatgat caagcaagat acaccagctt taagagatac agtaaggcag
     5641 agctagtaag caagcgtcag cagctgcaaa cagcaactgc agctgatgat atgtatgtca
     5701 aatcggttgg tcgcaaattt ttgattttcc ctgattatcg catagcagtg aagcctgtag
     5761 ccttgacaat caagaccaat gtgccaaatg ttgatatctt gttgaaccat aaaaagattg
     5821 ctgtatcaca gtcagaggat tttagcacaa ctattgaaag actgccggct gctgattata
     5881 aggcgagtat taatggctat tataaggatc gtaagattaa agtcagcaag gcctatgatg
     5941 gcaagaacca tacactagat ttgagggtta cctttaagac atttacggta accagcaatg
     6001 tcagagatgg cgagctttat attgatggcg agcgcgtgga aactttgaag gctgggcagc
     6061 ttcagctgga agaataccct gtgacagaaa tcgcaaaggc ctatattaaa aagacctttc
     6121 ctgatggcga gctaacctcc agcaagcatt cccttgctcc tgttgctgag ggctcccagc
     6181 tagagattaa cattgatcac ctcttgactg aggaacaggc gggacaggtg ttggtggcag
     6241 cctttgatca attgctcacc tatctcaatc aagggcagga tccagcaggt ctttcaactg
     6301 tttttgagca aggggctaat aatgcttttt acaaaggctt gaaggattcc atcaaagcaa
     6361 aatttcaaac tgataccaga aaggcttctc ggttaagcat tccgtctatt ttgttaagta
     6421 agctaactca aattggtaag cagtcttatc tagtggactt tacagctgtt tatgattttg
     6481 tttacgataa ggaaactgat cctgaaaaag gcacctcagg gaatgttcgt caagacttga
     6541 ctggtaagct gaccctgaaa aaatctgggg atagctacct tgttagtcag tctggtccta
     6601 aaaatattac agttgccagc gaaaaaaatc aggtcaagcc gtctattttc ccagaggggc
     6661 tagtgggaac ctggatagga catcgttcgg acatgacctt tacgatgata ttggctaagg
     6721 acggcagcat cacaacaacc attggaaaca aaaatgggaa tggctcacag accactaagt
     6781 ctgctaaaat taccaaggta gaggaaaaag gagatggctt gttcctctac actgtagctc
     6841 cagatgctga tatagcagct cttgttccag gaggtggatt gggtggtgtc aatgtcaaat
     6901 acgcttttgg tgtcaaatgg agtggagatg tcgctacgat agtggtttgg cagacagcaa
     6961 ataatgcggc atttgattac agtaagccaa tgcttggccc tgacatgaaa aagcaataag
     7021 tactttaccc tacaagttgg tctagcattt attgctagga ggaatcagca taaagaaaaa
     7081 gcctctcttt taatcttttg tggttaagaa gagaggcttt ttagtatagg gctgactgta
     7141 tgaggagcaa ccgatgtaat caatttagct gctgtagtcc ttctttaaag cttttagacg
     7201 gggcagtgac cctaatcatc tcttgagcca aggggtgtct aagggttagc tgatgagcgt
     7261 gcagcatgag acgctccgct ttttgcctgc tatagagggg atcaccaatt agagggtgtt
     7321 tatgatgagc gagatgtact ctgatttgat gtgttcgtcc tgtctctagg cgacagttga
     7381 ctaggcaggt ctgatcaaag gcttgtaata aggctagatg ggtgattgcc tcttgcccat
     7441 gcttactatc aaccacacgc ttgcgcctat cgtggcggtg acgtccgatt ggatcgcgat
     7501 aggttactgt ttgctgctct agctgacctt cgattagggc ccaataatct cgcttaatgt
     7561 ctcgatgctc caataggcga tttaagatcg gaaggataaa gggattttta gcaaagagaa
     7621 tcgctccact agtctccatg tctaagcgat gaaccacata gcaggtcttg ccagtatagg
     7681 cagagacatg gttgagcaag gcgagctcag tgggctcatt gccatgtgtt ttcatgccct
     7741 cgggcttgtt gacaatgatg aggtgttcgt cctgatacag gcaatccact aggccaggct
     7801 tacccattaa gatgccttta tcagggtagt cttcttggtc aaattgtagc ttgatgtgat
     7861 caccctgctt gacagggctc tgccagttaa tcagctcatc attgacccaa acatgctttt
     7921 tgatgcgcaa gaaatgtctg attttacggg gaatcaatag cctatcttct aataactcct
     7981 tgacagttgt cgcttgatag gggttaatga aggagatctg aaagcccatc tcaggcttat
     8041 ttgctgttgt cattgagcca gtcatggtat ttttcaatca aattgatggc catttgggtt
     8101 gcaagagtta cagagaaagc ctcggttccc tcgcgctcgt cactggcaac ctctaagcgt
     8161 gtctcatcat agacagcctt gaggctctct gctgacaggg tttctttaaa agcttgaaat
     8221 ttgttcatga tcatgtccta cctttctaaa tgtttgtgac aatgctatta tagcatattt
     8281 ttcatcaaag ctaatcattt gctcgatgat ttgtgctgcg ctaacagcgt gattcttttg
     8341 agaaaaaata agattagcta ttgtgaaatt gtctgtcttt tattatacta agaatagtct
     8401 gataaatata ttatttaagg acacgataac attgggatta tgaatcattt aggagaatac
     8461 tattgaacaa gccattgata aaatcctgtt tgcttgctct attgaccttg gccggcttga
     8521 ccagtatggc agcacaggct gatgtcaaca cttacaacca aggtaggaca tataacgata
     8581 caccctatta ttctgcttat catcactact atgaccacac gagggatact gctgacaatg
     8641 gtattgataa ttggggtcgt ctgacacgct atcactatta cagagagacc tattatcagc
     8701 ttgaggccga gcgtcagcag cttgttagga cttacttgga gttgaaggct tcatatgatg
     8761 atcaggtggc tcttagcagt caacgactac agcagtacca gtctggctgg tctgatctcc
     8821 aatcacgctt tgagcagctc aggaaaacca atcctgttgt aggcggtgat tatcggattg
     8881 ttgagctaga gggcaatttt caaagctatc agaccttgct gcagcagctt tctatggctg
     8941 attttgtcag ccagtacaaa gataggctgg ataccttgac tagacttgat acagagcgag
     9001 ctaggctcat tgacacctgg tgggaaagtg atagcaatta ctcagatctc aataccaatc
     9061 taacactagt caatggctat atcaaggagc tgaatcaggc tttacaggag cttcttaagg
     9121 accatcaagg taaaatgaca tcagatctgc agaccttggg tgaccgacag gccgagcttg
     9181 ctagacggct gacagatata gaaagcaggc ctaagagaca ggctaccagt caacctcgtg
     9241 gttcacagac acattggcga tcagccccta gagctgatgt tgccttgtgg aatgaattgc
     9301 gaaacgaagg agattatgct tctgctacga cagacaatgc tttgccattg cagccttatc
     9361 gagcggactt aacagctgtt catgatctag aagccttgca agcacaatct gatagagcac
     9421 accgcttgcg ggcaaaggaa attgtcttta cactgcagcg ttctaacatt agtcgtcagg
     9481 gcgatataga tttgtcagga gccattacag catttatcaa agaaaagctt ctcgtcactc
     9541 caaatgcgcg tggggtatca tctggcttta ggtggcaaat gcaaacctat gacaatgagc
     9601 gcttaaccat cactctaatg cctcaatatt atatgactga tgatcagtac aaggagtatt
     9661 acgaccatct caaggcttgg acagctcagc atatccagtc taccgataca gaggttgaga
     9721 aaattgataa gattcaagac tatatcatga caaactacca ctatgcgacc ggcaaggttg
     9781 gaggagtgac ccgtactggc atttctgtgc agacgccata tgcctttatc aaggacaagg
     9841 aggctgtttg tcaggcctat gcacagatgt ttaaggacat gggacgacta gctggacttg
     9901 atgttcatta tattcaaggc tatggagacc cagttggcgg cttatcaagt ctacatgctt
     9961 ggaatatcgt caaggttgat ggtcaatatt atcatattga cctgacttgg aatgatacta
    10021 ttgacagcac caatcacaat catacctaca ccctgcgagg caatgatttt atgagcaaaa
    10081 cacatttgtg gaatgctgcc tatgcgatct cagatagtga ctatgctgct tatcctagga
    10141 ggagcttcct gagatatggg acctatgcga ctaactattc aagaaataca ttttatccag
    10201 gatacagtta tgcttaataa tagctaatac catcaaaagc cctagaaagc ttgcttgatt
    10261 ctttcagggc tttttgatat gtcatggttt ttggtatagg attttgaaag aaattgttat
    10321 aataggataa aatgcttatg taacaggaga aaataaaatg aagagtatta gacgctatga
    10381 tgtcaatgaa gagtgggcac atactggctt agtagaggca ggcgattttt attttttaaa
    10441 ttattgtgta ggaaatgtcg gtcaagatat tgaggctcaa attaacggtg cctttgatga
    10501 aatggagcgt cgtttggggc tggtagggct gacgctagag gtcgttgttc aaatggattg
    10561 cttgtttaga gacatttgga atgtgccagt tatggaaaaa atcatcaagg agcgatttaa
    10621 tggcaaatac ccggctcgta aatttcttca aacagccttt gctcatcagg gtggtccgga
    10681 cggcttgcta tttcaggtag atggggttgc ttattcaaag catatctccg tatcctaaac
    10741 aatatgactt ggaggcttag tagtatcata aggctatgac atttttagaa ttattacaaa
    10801 agaaattttt tccaaaaaaa taccaagaaa aacaggcctt aaaggaaagg gcagcccagc
    10861 atatggctga caaagaggct actactcagg ctactgccac tgctttggcc gatcaggagg
    10921 cacaggcagg gcagactgag aggcaatcag tccttcaacg cagcaagtcc tatggggtca
    10981 aaaggaaaaa tcggccgatc tggcttcaaa ggctggaggc gattttgcca tcgcagcaag
    11041 gtcctattcg ccgctttctt cgtcgttacc atgttggtaa aatcctgctg attttgatgg
    11101 gtacctttgt cttgctgctg gggtcttacc ttttttacct ttcaaagaca gctaaggttt
    11161 ctgacttgca ggacgctctt aaggcgacga cagtcatcta tgaccgcaag ggagaatatg
    11221 caggcagtct ttctggtcaa aaggggacct atgtggagct tgacgctatt tcagatgatt
    11281 tggaaaaggc ggttattgcc acagaggacc gtacctttta taccaacaat ggtattaatt
    11341 tcaagcgctt tttattggct attgtgaccg caggacgctt tggtggaggc tcgaccatta
    11401 ctcagcagtt ggctaaaaat gcttatttgt cccaggagca gagcattaaa agaaaggcgc
    11461 gtgagttttt cttagcactt gaattgacca agaaatacag taaaaatgac attttgacca
    11521 tgtatctcaa taattcctat tttggaaatg gtatttgggg tgttgaggac gccagtcaaa
    11581 aatattttgg tacctcagca gctaatctaa ccttggacga ggcagcaacc cttgccggta
    11641 tgctcaaggg acctgaaatt tacaatccct attactcaat cgaaaaggca accaaccgta
    11701 gagatactgt tttgtcagcc atggttgacg ctggaaaaat cagcaagcag caggcacaag
    11761 aggcccaagc tattggtatg gggaaccgtt tagcagacac ctatgtcggc aagacagatg
    11821 attatcagta cccatcttat tttgatgctg ttatcaatga ggctatctcg cgctatggca
    11881 tctcagaaaa ggatattgtc aatgatggct acaagattta cacagagttg gaccaaaatt
    11941 accaagcagg catgcagacc acctttaatg aggatagcct atttcctgtg tctgagtttg
    12001 acggcagctc agctgaggcg gctagtgtgg ctctagatcc taaaaccgga gctgtcaggg
    12061 ggcttgttgg tcgtgtcaat agcacagaaa accagccctt tagaagcttt aactatgcta
    12121 ctcaagccaa gcgtagccct gcttcaacga tcaagcccct agttgtttat actcctgctg
    12181 ttgcagcagg ctggtcactg gagcacgaac tgccaaacag cgttcaggat tttggcggtt
    12241 atcagccgca taattatggc aattacgaat cagaaacaat tcctatgtat caggctttgg
    12301 ctaattccta caatattcct gctgtttcaa ttctggatca gttgggggtg gataaggcct
    12361 ttagctatgg tgaaaaattt ggtttgaaga tgagtgaaac caaaaaggag cttggagtgg
    12421 cgcttggtag tggtgtcacc accaatccgc ttgagatggc acaggcctat gcagtctttg
    12481 ccaatggtgg tgtcaagcat attgcccacc tgattaccag aattgaaaat gctaagggca
    12541 aggttatcaa gacctttaca gacaaaacca agcgggttat cagtcaatca gtggctgata
    12601 agatgactag catgatgctt ggaacctttt ctaatggtac agctgttaat gccaatgtct
    12661 atggctatac tctggctggt aaaacaggga ccacagaaac tgactttaac ccggaccttt
    12721 ccggtgatca gtgggtcatt ggctacacgc cagacgttgt tatcagtcaa tgggttggct
    12781 tcaatcaaac cgatgagcat cattatttat cagattcaag tgcgggcact gcctcagcaa
    12841 tttttagcac ccaagcctct tatatattgc catataccaa aggaagccaa ttcaaggtcg
    12901 ataacgctta cgctcaaaac ggtatttcag cggtttatgg gattaatgag accaatacgc
    12961 aagcaggtat tgattctcaa tccatcattg atagtcttag aaagtcagcc gaggaagctt
    13021 caaagtctat ttcagaggca gttgatcaat ctggtctcag agaaaaggcg caaagtatct
    13081 ggaagagtat tgttgactac tttagatagc ttgcgaaaat atctaaatcg tgttagaata
    13141 atcactacgg aggcgttatg gcacagaaaa aagcaagcct agcgtgtgta gaatgtggca
    13201 gccgcaatta ttctatcggg attagtagca cgcctagacc aacacgacta gaagtcaata
    13261 agttttgcaa atattgtaaa gcatacacct tacacaaaga aacacgttag aggagagcct
    13321 gatgggattc attagtggga tttttaagct tttaagggat acaacttggc cggatcgtaa
    13381 gcagcgctgg aaggacttta tttctgtcct tgagtataca gcattcttta cggtaatcat
    13441 ctttatcttt gaccagttgc tatcaaaagg cattttatca ttgattaatt tattctaagt
    13501 cattgcaatg atgagacctg ttatgattaa aattgcttgg aaaagcctag gctgaaacaa
    13561 tcgtttcggc ctttttgagt gcgatgggca ggttgtactc tgatagatgc aagaccaata
    13621 gaccacctac tatgcgggtg cgtaaagggg ttgatagcta ccgatagtta agggctatag
    13681 caagtagaaa ggcttgcagc tcagctgatc cgctgttatg actaaaggca ttgaccagaa
    13741 aggttcgttg gcagccaaca aagtgctctt accctgctat gaggggctat taatgcgttg
    13801 acagccaatc cttcttctat tataatgaaa gtgtgataac agcaatgcaa aggccagcag
    13861 aggctttttt ataatgaaag gaagtaacat gttagattct tttgataagg gctggtttgt
    13921 ccttcaaact tactcaggct atgaaaataa agtaaaagaa aaccttttgc agcgtgctca
    13981 aacctataac atgctagaca atattctccg cgttgagatt cctacccaaa cggtaaatgt
    14041 tgaaaaaaat ggtcaggtca aagaggttga ggaaaaccgc ttcccaggat atgttttggt
    14101 tgagatggtt atgactgatg acgcttggtt tgttgttcgt aacacaccaa atgtgacagg
    14161 ctttgtcgga tcgcatggga accgctcaaa accaacccct ctacttgaag aggagattcg
    14221 tgctatcctg ttgtcaatgg gacaaactgt tgatgtcttt gataccaaca ttaaagaggg
    14281 cgatatggtt caaatcattg atggcgcctt tatcgggcaa gagggtcgtg tcgtagaaat
    14341 tgaaaacaac aaggtcaagc tcatgcttaa tatgtttggc tcagaaacct tagcagaggt
    14401 cgagctttac caaatcgcag agctatcgtc ctgataggct cctaaagcta ttattcatac
    14461 cataaaaaat aaaaggctgg catcggctct ctaaaatacc gatgttaggc cttttttgtt
    14521 ggtcttctac aaccaagact caaattaacc aaaccctaaa aagagtcatt tttccttcgc
    14581 tttttaagtc tctaactgat cgccctagct tatttttaat ctagtaatcg caacaggtca
    14641 agagttaaat gatatcgcgc cgttattgat tggtatagac aaaaatacgc tcaaaaaaag
    14701 aaaaaaggat aggtaatata gtcctggttt gcttgataga tggtggttgg caaccaacca
    14761 ttcgagtact ttccttaact ataaactcct aatcaattct agcgtttaaa aaataagatt
    14821 attcttggag ggaagcaaag agcttctctc ctttttgagt tgtagcattc ttgatcctga
    14881 tcttataagc agagtcctgt ttgccgggct gttgagatga ataagggcat ttctatagtg
    14941 attatatagt gttgcagatg tgtgtatggt ttaaggtcta aatacccttc aagcttagtt
    15001 cttgggtagt cagttcggat tggctggctg atttttaagc ctttaatggc ttagtggtaa
    15061 gacaaaccag attacatttg ctaaaaagtc cctaaggcta caatcatttt ttgtgactaa
    15121 tataaaaact agaccttttg ggatttgtaa taatttagat tattgttttt aaaattagca
    15181 aatattaaac gcttttttat tgaagataca gatgatagta atggcagagc taaaaaataa
    15241 gagaaaataa aaaaagtcta caatttataa tgtaataaaa aaatgagttg actgttgtgt
    15301 tttaaaggct tttgtctatt tgtaatcggt taatttgcaa acaattctaa ggtatttctg
    15361 gctaatagta tgctataatg taatactgtt ctacaaccga cattaagagt taatgaaata
    15421 gtgttgtgtt gtggtaagtt tttaatcagg aagagtatat ttaggagcta gataccatgt
    15481 ctatagagaa tctctttacc aagcagcagt ggcgagagct tgagttgatt actttattaa
    15541 gtgaaacgaa aaatccatta tattataaag atgcttgtca gatgctggat tgttcggttt
    15601 taacgctgca atcgtgtatc acgaattctg tttttatgga agatttaggc aagctgttct
    15661 acaaggattc tcaatttcat attcattaca atcatcaaag tggcttaaag gaggtttatc
    15721 ggagagcctt gctagagtct ccttctcttc agttgatgtc ggccttgttt tttgatgatt
    15781 ttgcgtcatt agatgatctt gcagaggcac tttttattag cttgtcaacc ttaaagcgct
    15841 tgattcgtaa aaccaatctc tatttaaaag agcattttga tattatcatt tcggctaagc
    15901 ccattcgtgt agttggagat gaatacaata ttagactgtt ttacatcaag tatttttcag
    15961 aagcatatac cttttctgaa tggccttttg cttctctact taatgaaaac caccatgagc
    16021 aatttgttca attaatggca tctttgatag aggttaagat tgattttgcg atttttcgtc
    16081 aactcaagct attaagtgcg gttaatctca ttcgctacct caaaggcttt aaaattggga
    16141 agcataaagc actgagtagt ctttcattgg agttgttaca ggattctcag gagatgaaaa
    16201 agctgtcgca tttgtttgtg cttaaatttt cagtaccgct tgatgagctt gtcttgtcag
    16261 aaatgttttc caattattta gatgatgatt tggtattaga aaaatccttg caggtagata
    16321 aggttaagga ggaggttccg ggtcctcagt ccttgctgag ctggatagat ttgcttagtg
    16381 aaatggaggg agctacaggt attgtattgc caaataaata tgaggttgcc agatatcttc
    16441 atgccactgt tattttagga gtggaggata ttagtgaaag ctttctgatt tacgattata
    16501 aaaaggatta cttggccttc tttaaggagc attataccta tgtttatttt aggtttaccg
    16561 attatgtgaa gaggctattt aaggacgggg atatggagct tgctactaat ttgctcaaca
    16621 atttggttta ttccttgctg atagcctggg agaatttctt tttaaccatg tgtgaattga
    16681 tgaaaaaacc aaagctcttg attatagaaa gaagtcatgg cagtacggga agctttttga
    16741 aaaaatacat tggtgaattt tttgagatta ccatttttga taaattaacc atagaagcct
    16801 tgtgtctaca gcatgactat gacgtcatta ttactgatac ggtcattagg ggctgtgagc
    16861 atgctgatat ctttttcttt agtcgatttg tgccaaccgt tatagtcgcc aagcttaacc
    16921 attatctaag aaaacgaatg ggtagtatct ttgaaacgaa aacaactaac aagcttggga
    16981 acatcggcta ttgatagata tcggtatatt tcattaaaat agccacaact tgtcatggtg
    17041 taaaattagt gagctttgtt aatccaataa aattaggtag aatatagcta taggccaacg
    17101 tgtaattccc ttagggagta ggtgctttgg tctgggaaag agaaaaataa aaaggagaaa
    17161 caaacaacat gaagagttgt aaatcaaccc tagtttagat aaaaagatta attcttctat
    17221 tggtatcaaa ggaagtaatt ttatttcctc aaaactttta gcgaatttaa agactcgcat
    17281 cgactctgaa gctactttga aagcagaaac aactcaattg aaagccgata tagaaagaga
    17341 aaaacttact tctaaagaat taagcactaa actggaagag gtaacatcag atcgtgataa
    17401 tgctctcagt gaatctgccg atcttgccaa caaactctca gtagctcaag cagaagcaga
    17461 tcgtttaagt caggctgttg atagtctggg tcgattgact aactctgcta agcgtgagct
    17521 cacagagaag cttgctgaga ttgatcaatt aacacaggac aaggttaaag cagagactga
    17581 ccttgaaact gctaatgcta acatcacaac acttcaagag gagctggcag gtgctaaggc
    17641 taatgttgat aagcttgcaa aggaaaaagc tgcggcagat caggcacttg ctgaagctaa
    17701 tgcaagagta tcaaatcttg ggcaagaggt agcagcagct aataatagag tggctgacct
    17761 tgaagcgcaa ttagctgaaa aaacagccga gcttgatgtg gttaaggcag acaaggcaga
    17821 gcttgaggct aaggttaagg agcttcaaag cctgcttgag caaaaggatc gtagcaatgc
    17881 tgatcttcaa gctaacattg agcgcttgaa gcaggagctt gctgacaagt ttaaggatca
    17941 ggcacagcct cgttctaaga ctcctcaggc atcgaactcg gttgcaaagc aaaaagcaag
    18001 taagccagcc gcaaaaccag caggccagct accatcaaca ggtgaagcta ctgcaaatcc
    18061 atttttcact gctgctgcag ttgcgattat gacaagtgca ggcctagtaa cagtcatgcc
    18121 aaaacgccaa aaaaattaag ctattctcaa ttctctcccc tttaactatt gttttatagc
    18181 attttactaa tggacattgg cattcctata aactctattg agcttcttat ctgatagcaa
    18241 ggataagggg ctttttagta gcttagcaag cactccttgg tcaagctcaa tacctctttg
    18301 agagcttaaa actagagcta gaccagatct aaaaccaagt gagatgatag cggatatttg
    18361 gctgttttat gagttggctc gtaaggcttg agcttatgcg tcgcagagac gcgctatcta
    18421 gtctaaaggg ctttagcaat gtcgtgacaa acgcatgaag acagttacac tttctcatag
    18481 cgagttttta tcatcagtat agtttttttg gcaatatgtt atgaaatagt caaatagcaa
    18541 tcgagaaact ggtgatattg caatgcaaaa ccgctgaaca tagattaaaa aaatgcatgc
    18601 agctagaaaa tggttacatg catttttgtg atgccgacgt cgtggcagca atattgcttg
    18661 cccattccta aaagtctgat atcgtgctat aataagaaga ctagactttt tacatgggag
    18721 aattcacatg acattttaca atcacaaagc cattgagcct aagtggcagg ccttttgggc
    18781 tgataatcat acctttaaaa cggggacaga tgcctcaaag cctaaatttt atgctttaga
    18841 tatgtttcct tatccttccg gtgcaggtct tcatgttggg catcctgagg gttacactgc
    18901 aactgatatt ttaagccgct tcaagcgtgc acagggttat aatgtcctcc acccaatggg
    18961 ctgggatgcc tttggtctgc ctgctgagca atacgcgatg gatactggta atgaccctgc
    19021 tgagtttaca gcagaaaaca ttgccaactt taaacgtcag atcaatgctc ttggcttctc
    19081 gtatgactgg gatcgtgaga tcaatacaac tgatcctagt tactacaaat ggacacagtg
    19141 gattttcaca aaattgtatg aaaaaggcct agcctatgaa gctgaggtgc ctgttaactg
    19201 ggttgaagag ctgggaacag ctattgcgaa tgaggaggtt ctccctgatg gcacatcaga
    19261 gcgtggaggc tatccagttg tccgtaagcc catgcgccaa tggatgctca aaatcacagc
    19321 ctacgcagag cgcttgctag cagatctgga ggaagtggat tggccagagt cgatcaagga
    19381 tatgcagcgc aactggattg gtaaatcaac aggggctaat gtaaccttca aggtcaaaga
    19441 taccgataaa gacttcaccg tctttaccac acgacctgat accctgtttg gtgcaaccta
    19501 tgctgttttg gcaccagaac acgccttagt agatagcatt actacagcag agcaagcgca
    19561 ggctgttgct gagtacaaac gccaagcgag cctcaaatct gaccttgctc gtaccgatct
    19621 tgccaaggaa aaaacaggtg tctggacagg agcctatgcg atcaacccgg tcaatggcaa
    19681 agaaatgcct atctggattg cggattatgt gcttgcaagc tacggtacag gtgctatcat
    19741 ggcagtgcca gcgcatgatg agcgtgactg ggcatttgca aagcaattca atcttgagat
    19801 tattccagtg cttgaagggg gcaatgttga tgaggctgcc tacacagagg acggtattca
    19861 cattaattct gacttcctag atggtcttga taaggcttgt gccattgcta aaatggtggc
    19921 gtggctggag gagactggtg tcggtcatga aaaggtctct tatcgcctac gtgactggct
    19981 gttcagtcgt cagcgctact ggggtgagcc aatcccaatc attcattggg aggacggtac
    20041 ctcgacagcg gttcctgagc aggacctacc acttgttttg ccagtgacca aggatattcg
    20101 cccatctggt acaggagaat caccactagc taacttgact gactggcttg aggtgacccg
    20161 cgaggatggg gtcaaagggc gtcgtgagac caacaccatg ccacagtggg ctggctcaag
    20221 ctggtattac cttcgctata ttgacccaca caatgatgag caattagctg ataaggacct
    20281 gttaaagcaa tggctgccag tagatattta cattggtggt gctgagcacg cagtgcttca
    20341 tctgctttat gcacgcttct ggcacaaggt actctatgat ctgggtgtag tgccaaccaa
    20401 ggagcccttc caaaagctct ttaatcaagg catgattttg ggaaccagct atcgcgacca
    20461 tcgtggggcc ttggtcgcaa cggataaggt tgacaagcgt gatggtagct tcttccacat
    20521 ggaaacaggc gaggagcttg agcaggcccc tgctaagatg tctaaatcac tgaaaaacgt
    20581 tgtcaaccca gacgatgtgg tggagcagta cggagcagat accctgcgtg tgtatgaaat
    20641 gtttatgggg ccacttgatg cgtccattgc ttggtctgaa gaaggccttg agggagcacg
    20701 caagttccta gatcgtgttt accgtttgat cacgacaaag gaaattgttg cagaaaatag
    20761 cggagcttta gataaggctt accatgagac tgttaaggca gtcacagaac aaatcgaagg
    20821 catgaaattc aatactgcta ttgcccagct catgattttt gtcaatgcag ccaataaaga
    20881 ggacgagctt tatgtggcat acgccaaagg cttcgttcaa ttgctagccc catttgcccc
    20941 acacctaggt gaagaattat ggcagatcct gacagcttca ggtcaatcca tctcgtatgt
    21001 tgcatggcca acccatgacg atagtaagct cgttgaaaat gatgttgaaa tcgttgttca
    21061 aattaaagga aaggtcaagg ctaagcttgt cgtggcaaaa gacctctcaa gagaagagct
    21121 agaaaaagta gccctagcac atgataaaat acaggctgaa attgcaggca aggaagtggc
    21181 aaaggtcatc gttgttccta ataagctcgt taatattgtg gtgaaataaa gaccctagca
    21241 aaaaatgcct tccttataat tttgagccca atactataaa aagctgataa ccactcgttt
    21301 acatgagtgg ttattcttgt tttgtaacac gctattaaaa ctgatattga agaagcttga
    21361 agataatagt aaaataaaac cctaaactta tttaataaat ggaggatttt tcaacgtgaa
    21421 aaaattagtt ttagccagtg cagcagcact tgtattagca ggagcaactg taagtacagg
    21481 aacagtaagt gcgaatagtt caagatataa ttataccggt tggaatcaag gtgggtactc
    21541 atggaaatat ttgcgcctaa gaaataaaaa tccttattca cgtcgtaccc ttacagaaga
    21601 ctattctgat caaagaaaga atgaagcaaa agatagtatt aaagaattga gtaagcttag
    21661 tgataaagag aaaaagaatt ttgctgatag aattgatgct ttgactgaca cctatgcaat
    21721 cagctctatt ctatcagaag ctaaaaataa gaataatgac tatttagaat ttgataaaga
    21781 atatgaggct ttattcaatt caaataagta taagttagaa atagagaaaa taaaggatcg
    21841 tgtgtacttt gatgaaggtt actcagctag acaagggatt aatgactt
//
LOCUS       DARYVE010000033        21254 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYVE010000033 DARYVE010000000
VERSION     DARYVE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21254
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            556..771
                     /locus_tag="TVW25_001173"
     CDS             556..771
                     /locus_tag="TVW25_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1378806.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            768..1544
                     /locus_tag="TVW25_001174"
     CDS             768..1544
                     /locus_tag="TVW25_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1378807.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(1613..2869)
                     /locus_tag="TVW25_001175"
     CDS             complement(1613..2869)
                     /locus_tag="TVW25_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1378808.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(2955..3914)
                     /gene="nrdF"
                     /locus_tag="TVW25_001176"
     CDS             complement(2955..3914)
                     /gene="nrdF"
                     /locus_tag="TVW25_001176"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1378809.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(4059..6218)
                     /gene="nrdE"
                     /locus_tag="TVW25_001177"
     CDS             complement(4059..6218)
                     /gene="nrdE"
                     /locus_tag="TVW25_001177"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1378810.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(6239..6457)
                     /gene="nrdH"
                     /locus_tag="TVW25_001178"
     CDS             complement(6239..6457)
                     /gene="nrdH"
                     /locus_tag="TVW25_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1378811.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            6879..7142
                     /locus_tag="TVW25_001179"
     CDS             6879..7142
                     /locus_tag="TVW25_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1378812.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            7147..8880
                     /gene="ptsP"
                     /locus_tag="TVW25_001180"
     CDS             7147..8880
                     /gene="ptsP"
                     /locus_tag="TVW25_001180"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1378813.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            9082..10509
                     /locus_tag="TVW25_001181"
     CDS             9082..10509
                     /locus_tag="TVW25_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1378814.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            11162..12376
                     /locus_tag="TVW25_001182"
     CDS             11162..12376
                     /locus_tag="TVW25_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1378815.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            12472..13041
                     /locus_tag="TVW25_001183"
     CDS             12472..13041
                     /locus_tag="TVW25_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1378816.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            13042..14994
                     /gene="gyrB"
                     /locus_tag="TVW25_001184"
     CDS             13042..14994
                     /gene="gyrB"
                     /locus_tag="TVW25_001184"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1378817.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            15143..16867
                     /gene="ezrA"
                     /locus_tag="TVW25_001185"
     CDS             15143..16867
                     /gene="ezrA"
                     /locus_tag="TVW25_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1378818.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            17238..17519
                     /locus_tag="TVW25_001186"
     CDS             17238..17519
                     /locus_tag="TVW25_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378819.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(17704..18159)
                     /locus_tag="TVW25_001187"
     CDS             complement(17704..18159)
                     /locus_tag="TVW25_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1378820.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            18390..19697
                     /gene="eno"
                     /locus_tag="TVW25_001188"
     CDS             18390..19697
                     /gene="eno"
                     /locus_tag="TVW25_001188"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1378821.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(19833..20069)
                     /locus_tag="TVW25_001189"
                     /pseudo
     CDS             complement(19833..20069)
                     /locus_tag="TVW25_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20278..20499
                     /locus_tag="TVW25_001190"
     CDS             20278..20499
                     /locus_tag="TVW25_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1378822.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            20501..20761
                     /locus_tag="TVW25_001191"
     CDS             20501..20761
                     /locus_tag="TVW25_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1378823.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
BASE COUNT         6181 a         3938 c         4853 g         6282 t
ORIGIN      
        1 attattttaa ttataatatt catctaaatt atctttattt ttaattcaaa aatataagca
       61 attgattcac ataaacaaat tgagacgaac agtagattgt agctatatca caggtgagat
      121 agtaatgatc gtgcgaaaca ataaactgat ttttccatgc gggatatttg ttatcagtga
      181 gttgaatgga actagcagct attgttttat tgttagtcat ctagtgtttt taaggtgctt
      241 attttctgtt acaacagtga tgacaacagg ttaagctaag ttcgatggag cttggttttt
      301 tattgttaca agaaagctca tagatggtga ttgcattctt ttatcatatg acaatgtttc
      361 tatttttgac aaatattatt gtcaaaaagt aaatgatctg ttacactgga gttggactca
      421 tgaaagaaaa aagtaatcag taggataaca ataacaaagc tattttaagc ttataccatt
      481 gtgtcaatgg attgttgccg gaaatgactg gtgctttctg ttcaatcagg agacagcatt
      541 tattaggagt gaagcatggc ttataggttg agaaatcggc tcaaggagct acgagctaga
      601 gatggcatta atcagacgca gatggcagca ttagcaggtg tttccaggca gaccattagc
      661 ctcattgagc gaaatgaata cacaccatct attattattg caatgaaaat tgctaaagta
      721 tttaatgaac caattgaaca agtatttagc ttagtggagg gcgagagatg aaagctttta
      781 tgacggaaaa ggacagtacg ttggtgagaa tacttaagtc attactgctt ggatcaggga
      841 ttggcttagt gttaggtggc cttgttggtt ttggtttagc taggtttaac atattagaaa
      901 atggctttcc gatatcagaa gaagacacca taactggaat aaagtgggga atgagacccc
      961 ttgttatcgt gcttatgctg ctgagcattt atgatattta tcaagttgtc aaagaatatg
     1021 ctagatatgt caagctaagc gatgatgaaa cagaggagct gtaccgttac attaatctta
     1081 agcatgccta tgctttagga tttagcgcta tggctatggt cttgaatata gtcgtttttt
     1141 ctttgggata tagggtgcct attgctaata atgctagcta tcttggtttg acttttccta
     1201 tttacgaggc tctgatgctt gtggttatta gtgttctcca tgcttatatt ttgaaggttt
     1261 atactcggat tcgcggggtc aagatgacgc ttgctcctac cttaaaggaa ttaaagcaga
     1321 atatcttaca acaggacgag gcagaattgc aggctaatta tcaaatgtct tttgaggttg
     1381 tcatgggcct tagtggcttt atattaccag gcatttacgt aatattattg cttttatcta
     1441 tgatttttca aagggttgag ctgaccggac taatcattac tgctagtatt cacctctata
     1501 ttctggtgaa atcctttaaa tcagcacatg atttttatag gtaaggcgta aggttttacc
     1561 tactcaagaa ttgttataca gcaaaaaagc tttgataagc cattactggc gatcaaagct
     1621 ttttgtgttt gttgaaaaag aggctttttt gaaagagctg ttggctgaga tagcttgtca
     1681 aacctacaat tgcaagcggc acaaggctaa tgagaggttg tccggtaatt tcaatgagaa
     1741 aaagaggagc agtaagaggt atctgattaa tgattcccaa aaagagggtc gctccaatga
     1801 caatggccaa gggaagtggt acagagagat aacctagctg attgctaagg cttgccagta
     1861 gcaagccact agctcctcca agcatcatag aaggagcaat tttgcctcct ttagctccag
     1921 aggcaaatac tgcatagaca gcagctgctt tacttagtaa gagcgaggcg gtataagata
     1981 ggctgacatc atggtgtagc agcaggagga gaccggcctt gccattgcct aaaatctctg
     2041 ggaaataaag gcttaaacaa gcactaaagc caaaagcccc taagacacga gggataaacc
     2101 atcggctctt aggctttgcc tttggtgcgt tttggagcag ctgctggtag caaaaggcca
     2161 gaaatgctaa gatgggactg gcaatgatag cccaaaggac tgttgtcagt tgccaggctt
     2221 gtgggagaat gagatactgt atgtcctgat gtccgcttag aacaagcaca ctttgaacag
     2281 cagtaaaggc agttatagct gccgcgtaaa tgtgtttaac tgagcatttt ttgacaatag
     2341 cctccatgat aaagacaatc gtagctaatg gtgcctggta aacagctcca agggcagctc
     2401 ctgaagcaca ggctaaaagc aatccttgct ctgctgctga tgcgtttata gctttattgc
     2461 aagcggcagt cagtgccaca gcaacctcac gtgaagcacc ttcacgaccg acaggtgctc
     2521 ccatggagac ggttattaat tgcagccagc catgacaaaa ttgtgtccaa gggctgaaat
     2581 ccttttgctg actgagtgtt tgttggatag gctgaatagg cttggctttt ttagcaagta
     2641 gctgccagcc gagaccagca atagctccag ccaacaatag agataaaaaa cgcctttctg
     2701 gagctaccgt tgcaatcatg gtgctaaaag acccagattg gtatccaaag ctaatagcct
     2761 gtatgaaatg aatggcttga gtgagcacgt aagccaccac accagcaatc acaccagcta
     2821 ccaccagttg gcccgtccat gttaagaaag taatcaatcg agtaatcata tcttttatta
     2881 tagcagataa aaagagcctg agactactca ggctccaaaa tatagataaa tccaatcttc
     2941 atgagaagct ggacttatag cccataattg taatcgtcat cagtcatagc ttcaacagta
     3001 ccaagaaggt agccattacc aacttgagag aagaaatcgt ggtttgacgt gccggttgaa
     3061 ataccattca taacgattgg gttgacatca ttggcagtgt ctggaaaaag agggtcctga
     3121 ccaaggttca tcaaagcctt gttagcgttg tagcgtagga aggtcatcac ttcctcggtc
     3181 cagccaacct catcatagag ggtcttggtg tattgctctt cattttcata tagctgatac
     3241 agcaggtcat acatccagtc acgaaggctt tcttgctcac tctctgatag ctcattaaag
     3301 cccagctgaa acttgtagcc gatataagtg ccatgaacgg actcatcacg aatgatgagc
     3361 ttaataattt cagcgacatt agccagctta ttgttgccca gataatagag tggtgtaaaa
     3421 aagccagaat aaaatagaaa ggtttcgaga taagtcgagg ctaccttttt ttgaagggca
     3481 ctgccatttt cataaatgtc gttgattatc ttagccttat tttgaagaaa tacgttgttg
     3541 ttggtccact caaaaatgtc ttcaatttct tttttggtgt ttagggtcga aaagattgat
     3601 gagtaggatt tagcatggac agactccata aattggatat tgttaagaac tgcctcttca
     3661 tgcggggtgc gcacgtcctt gcgaatggct tcgactcctg actcagactg catcgtatca
     3721 agaagggtta gcccgccaaa gaccttacct actaaatcct tttcaacagc agataatctg
     3781 cgccagtcat caaggtcatt tgatagtgga atacgtgtat caagccagaa ttgctccgtc
     3841 agcttttccc aggttgactt gtcaatgaca tcttcgattt cattccagtt gattgcttca
     3901 tagtatgtgg tcatgagttt ctccggtaga ttgtaatata gggttaggta tgctaggagg
     3961 agagccttga gtgctggtct atcattagga caggtgcact gacacatcag ctaggctctg
     4021 acattaagga ctggtccacc tcactgccat tcacttggtt agatgacaca gctttcacac
     4081 tgattggctc cgacctcctc gccatcatcg gtaaaggtgc ggatataata gattgatttt
     4141 atccctttat taaaggcgta atgtctcaaa atagataggt cacgagtggt ttgcttgctt
     4201 tctgttttcc attcgtagag ctcctttggc aattcgctgc gcaaaaagag tgttaacgac
     4261 agtccctgat caacatgctt tgtagcagct gcatagacat caatcacctt tctcatgtcc
     4321 atatcatagg cagatgtgta gtaaggaatg gtgtctgtag ataggccgtt ggctgggtaa
     4381 taaatcttgc cgattttctt ttcctgacgt tcttcgatcc gctgagtaat cgggtgaata
     4441 gaagcagagc agtcgttgat ataggaaatt gatccattag gagcaactgc cagacggttt
     4501 tggtgataaa ggccatctgt cataatcgct tgacgcagcg ccttccagtc tgctgcttgc
     4561 ggaataaagt gatccttgaa aaggctttta accagctctg attttggcac acattctcct
     4621 gtgatgtact ggtcaaaata agcaccgcta gcatatgttg atttttcaaa gccaacaaag
     4681 gttgtctgac gctcgcgagc gatctgattg gattcgacaa gcgtccagta attcatcagc
     4741 ataaagtaaa tatcagtaaa ttcgatagat tctgggctgc catattcgat atggtgctga
     4801 gccaaatagg aatgaagccc catagcccca aggccaaagg tatgtgcttg actgttacca
     4861 tttttaacag ttgggactgc ttcgatatta gaggagtcag tgacaaaggt cagggcacgt
     4921 gtcatggctc tgatggaacg accaaagtca ggtgacgtca tcatgtttaa gatattagtt
     4981 gatcccagat tgcaggaaat atcagttccc attttgacaa actcctgcgc atcattaatg
     5041 agactaggcg tttgaacctg tagaatttct gagcataggt tgctcatgat gattttaccg
     5101 tcaatagggt ttgacctgtt ggcagtgtcg atgttgataa catagggata gccagattcc
     5161 tgctggagct tggaaatctc tgtctccaaa tcacgtgctt tgatttttgt tttggtgata
     5221 ttaggattgg caaccaattc gtcatacatg ctagtaatat caatgtagtt aaatggcagg
     5281 ccgtattctc tttcaacact ataagggcta aagagataca tgtcagcatt gtgacgagca
     5341 agctcataaa acttatctgg tacagtaata ccaagtgaca atgtcttgac ccgcaccttt
     5401 tcatctgcat tttctttttt ggtagacaaa aaagcgataa tatcagggtg aaagacgctt
     5461 aaatacacca caccagcccc ttgacgctgc cctagctggt tggaataaga aaagctgtcc
     5521 tcaaatagct tcattacagg cacaacacca gaagcagctc cggcatagcc cttgattgga
     5581 gcgccagcct cacgaaggtt ggataggcta atgccaacac cacccccaat acgggataat
     5641 tgcaaggcag aattaataga gcggccaatg gcattcatat catctgtcac ctgaaggaga
     5701 aagcaagaaa ccagctcacc acgacggctc cgtccagcat ttaaaaaaga aggagtagca
     5761 ggttggtaac gctgattaat catctcaatg gctaagtcct tagctaatgt ttcatcacca
     5821 tcagcaaaat aaagggcatt gaacatgacc cgatcctcta tgctctctaa gtagaaattg
     5881 ccatcattgg tttttagggc atactgctga taaaatttat aggccgccat aaatgattta
     5941 aagcgaaagc cctctgcttg aatgctcttg gctagatggc tgataaattc aggagaatag
     6001 ttttggataa aggctgattc aatatagtca ttgtctacaa gataggcaat cttttcgttg
     6061 atagaagaaa atgacatggt gttaggaata acattttcgg taaaaaaagc ctccaaagct
     6121 tccttgtctt tatgaagtgg aatgctgcca tcaacaggac ggttaatttc attgttgagg
     6181 cgaaagtaag aaatatcgcc aagatctttg agactcatat caattgttcc ttgtctagtt
     6241 aaataatatc ttttaatttt gctggctgaa accctgagaa tactatctgc tctgtctcaa
     6301 taacaggagc agcagtaaag ccaaggctct taacatagtc cactttttct ggatgctcat
     6361 caatattaat ctcttggaaa gcagctccat gctgttctaa aaatttctta gtcattttgc
     6421 actgcatgca attgtgcttt gagtatactg taatcattgc tcgtccttcc aactattagt
     6481 ctttcactca attttaggaa aaatcaaatg actctaatag gatataaaaa atgttcctaa
     6541 aaagcaaacg atttatttca gaatagcaca agatattgtg gttgtgtgtg agaatatttc
     6601 taaatattgt gttatcctct cttatcactg ataattgcta caagaggctt gtagttctta
     6661 aatgcatact aatcaggttg gaaggcttat ttgacattat gaaaatcatc atgtaagaaa
     6721 tattgacaac aaatgaaaat acaagaaaac tgtttcatga ttttttcttg ttagaacatt
     6781 taaccttgaa aataaaaaag cattgtgcta taatcactta ttgtaagggt tatcatgtga
     6841 tagctcgaaa atacacaatt caaaaggaga accatattat ggcttcaaaa gactttcaca
     6901 ttgttgcaga aacaggtatt catgcacgcc cagctacctt acttattcaa acagcaagca
     6961 aatttgcttc agatattaca cttgactaca aaggtaaagc agtaaatctt aaatcaatca
     7021 tgggtgttat gagccttggt gttggtcaag gtgctgacgt aacaatcaca gcagaaggcg
     7081 ctgatgcaga tgacgctatt gcggcaatcg aagaaactat gactaaagaa ggattggcat
     7141 aagactatga cagaaatgct taaaggaatc gcagcctctg acggtgttgc tgttgccaaa
     7201 gcatatctgc tagttcagcc ggatttgtca tttgagacta tcacagtcga ggatacaaat
     7261 gcagaagaag ctcgccttga tgttgcacta caagcttcac aagacgagct ttctgttatc
     7321 cgagaaaaag cagtagaaag cctaggcgaa gaagcggcag cagtttttga tgcccattta
     7381 atggttcttg ctgatccaga gatgatcagc caaattaaag agactattcg tgcgaagcaa
     7441 acgaatgctg aaacaggtct aaaagaagtg actgacatgt tcatcacaat ctttgaaggc
     7501 atggaagaca atccttatat gcaagagcgt gcggctgata ttcgagatgt cgctaagcgc
     7561 gtcttggctc atttattagg tgttaagctt ccaaatccag ctacaattga tgaagaagca
     7621 attgttattg cacatgattt gactccttca gatactgcac agcttaacaa acaatttgta
     7681 aaagcatttg taacgaacat tggcggacgt acgagtcatt cggctatcat ggcccgtaca
     7741 cttgagattg cggctgtgct tggtacaaat gatattacta agcgtgtcaa agatggtgac
     7801 cttattgctg ttaatggtat cactggtgag gttattattg acccaagtga ggagcagatt
     7861 cttgctttca aggaagctgg agaggcttat gcgaagcaaa aggctgagtg ggctctgctt
     7921 aaggacgcac aaactgtcac agcagatggc aagtactttg aattagcagc aaacatcggt
     7981 acacctaagg acgttgaagg tgtcaacgat aatggtgctg aggcggtagg tctttaccgt
     8041 actgagtttc tttatatgga ttctcaggat ttcccaaccg aagatgagca atatgaagcc
     8101 tacaaggctg ttcttgaagg aatgaacggc aagcctgttg ttgttcgtac aatggatatc
     8161 ggtggggaca aggagcttcc ttactttgat ttaccaaagg aaatgaaccc attccttggt
     8221 tttcgtgcct tacgcatttc aatctctgaa acaggtaatg ctatgttccg cacacaaatt
     8281 cgtgctttgc tgcgtgcttc tgtgcatggt caattgcgta tcatgttccc gatggttgcc
     8341 cttctaaagg aatttcgtgc tgctaaagtc gtatttgaag aagaaaaggc tagcttgctg
     8401 tctgagggtg ttgcggttgc agacgatatt caggttggta tcatgattga gatcccagca
     8461 gcagcaatgc ttgctgacca atttgccaag gaggttgact tcttctcaat tggtacaaat
     8521 gaccttatcc agtacacaat ggcagcagac cgcatgaacg agcaagtgtc atacctttac
     8581 cagccatata acccatcaat ccttcgtttg attaacaatg ttatcaaagc agctcatgct
     8641 gaaggtaagt gggctggtat gtgtggtgaa atggcaggtg accaacaggc tgtgccgctt
     8701 cttgttggta tggggcttga tgaattttca atgtcagcaa catctgtgct tcgcacacgt
     8761 agcctgatga aaaagcttga ttcagcgaaa atggcagagt atgctcatcg tgcactcaca
     8821 gaatgctcaa ctgctgaaga ggttcttgag cttgccaaag agtatattac agaagcttaa
     8881 atagaaataa cgaggagctg gttttgtccg gctctttttt actagaaaaa tgactaatca
     8941 gatccatatg aaagcttgct ttataaagta gtttgatgtt tcaagtttta tcagaatttt
     9001 cagactcttc ctgtagcgaa ttgttgaaat atgctaaaaa agtgatagaa taatagtacc
     9061 attataaaag gagaaaaaag tttggctaaa caatataaaa atttagtgaa tggtgagtgg
     9121 aagctctctg aaaatgagat caagatctat gcaccagcaa ccggcgagga gttaggtagt
     9181 gtaccagcta tgtctcgtga agaggttgat caggtttatg cgtcagctcg cgctgctctt
     9241 gcagattgga gagcgctttc ttatgttgag cgtactgctt atttgcacaa ggctgctgat
     9301 attttggtgc gtgatgctga gaagattggt gctgttctct caaaagaggt tgcaaagggt
     9361 tataaggctg ctgttagtga ggttattcgt acagcagaaa ttattaacta tgcagcagaa
     9421 gaaggccttc gtatggaagg cgaggtcctt gagggtggca gctttgaggc tgctagtaag
     9481 aaaaagattg cgatcgtacg tcgtgagcca gtgggacttg tgcttgcgat ttcacccttc
     9541 aattatccga ttaacctagc aggctcaaag attgctccag cccttattgc aggaaatgtc
     9601 gtggttctta agccgccgac acaaggctct atttctggct tgctcttagc agaggtattt
     9661 gcagaagcag gtcttcctgc tggagtcttt aataccatca ctggacgcgg ctcagttatt
     9721 ggtgattaca tcgttgagca tgaggctgta aactttatca actttactgg ctcaacgcca
     9781 attggagagc gaattggtaa attagccggc atgcgtccga ttatgcttga gcttggtggt
     9841 aaggattcag cgattgtctt agaagatgct gatattgcct tagctgctaa aaacattgtt
     9901 gcaggtgcct ttggctactc aggtcaacgc tgtacagcag ttaagcgtgt gcttgttatg
     9961 gaaagcgttg cagaccagct ggtagcagag attaagggct tagttgagaa attacttatc
    10021 ggtatgccag aggacaatgc tgacatcaca ccattgattg ataccaaagc ggcagatttt
    10081 gttgaaggtc tggttaatga tgcagcagac aagggagcac aggcgcttac tgaaatcaag
    10141 cgtgacggta atttaatttg tcctatcttg tttgatagag taacaactga tatgcgcttg
    10201 gcttgggagg agccatttgg tccggtgctg ccagtgattc gtgtaagctc tgtagaagag
    10261 gcaatcagca tttcaaatca atctgaatac ggtttgcaag cgtctatctt tacgactaat
    10321 tttccacagg cctttgctat tgctgagaag cttgaggttg gtacagtaca cattaacaac
    10381 aaaacccaac gtggtacaga taatttccca ttcctagggg ctaagaaatc aggagctggt
    10441 gttcaagggg tcaaatattc aattgaggca atgacaagtc tcaaatcagt cgtatttgat
    10501 attcaataac aaaaaagcta gggtatctta gtttgaaagc agttgcacat ttgtgcggct
    10561 gttttatttg tgtctctagt tttaacagct agctatgcaa gaaggtgagt tgtcccaacc
    10621 tcaaagatga gatctaaata tttaatgatt ttggggtcgt aaaaaagttt agagtgtttt
    10681 gatctcctta agatgtgagt gtacaaagtc tcgccaacag ccagcaggac tagccattga
    10741 ggtcaaggaa gctgctaaaa tagctgatgg ttcaaaagct tggtgaaagg cttaatatct
    10801 atcattgcta ttttgagggc tttccattat aatatgaata ctagagctac ttgtcggtct
    10861 gcctcttgag ctgtgagata gctgttggat ttagttgtct ccttgtccac aaaaggctta
    10921 gaggcaaagg ctgtggctat gcttcttgct tcttttagtg aagtgtatga gatcttatga
    10981 aaactcatat aggctttggt atctttgcaa gaggactaat ggcttgcttt acttgccttg
    11041 atagagggct gggattgagg ggtgatgacc tgcggtggtc atctctagag ctccttgctt
    11101 ctttttttat gtagactaat ggtttagact gctagcttcc ttgtttagaa agtaggacat
    11161 catgttaccc aagagaaaat taattgatca acgtcttgat tatgccatta tttttcctgt
    11221 tttttgtttg ctaatatttg gtctggtatc tgtatatgtg gcagcaagtc atgattttcc
    11281 gcaaagcctc gccactgtta tgcttcaaca ggttctctgg atccttcttg gagctgtgat
    11341 tgcctttacc ctaatgtttt ttagcacaga gattctgtgg aaattaacac ctgtctttta
    11401 tcttttgggt gtgctattaa tggttctgcc actcatcttt tttagccctc ggctggtagc
    11461 tgctacaggg gcgaaaaatt ggattacgat tggctcaacg accttgtttc aaccatcaga
    11521 atttatgaaa atatcctaca ttctggcaat gtcttggtta acggtctggt ttaagagaaa
    11581 gcaggagaga agtcggtttt tagatgattg gaagctcttg ggcttatacc ttgtcttgac
    11641 gttgccggtc atggtcctgc tagcactgca aaaggactta ggaacagcta tggttttttt
    11701 agccatctta gctgggatta tcttaatttc aggaatttct tggtggctta ttttaccagc
    11761 tttggtacta gtctttttac tggtttcagc ttttttcttt gtttttttgt tgccagaggg
    11821 aaaagaattc cttttaaaaa tgggaatgga tacctaccaa ttgaatcgta tttcagcttg
    11881 gctgacaccg tttgatttct cagataccat tgcctatcag cagacgcaaa gtatgatttc
    11941 gattgggagt ggtggctttt ttggtaaggg ctttaatcag cttgagctgt cagtaccagt
    12001 cagagaaagt gatatgattt ttacagtgat cgctgaaaat tttggctttc ttggtgcagc
    12061 tagcttactg atcttgtatt taatactgat ttaccgcatg cttagggtga cctttgcatc
    12121 gaataacctt ttttatacct acatttcaac cggctttatc atgatgatac tatttcatat
    12181 ttttgaaaac attggcgcag cagttggtct gctacctttg accggtattc cccttccctt
    12241 tatttctcag ggcggctctt ccttgatttc aaatctgatt ggggtcggcc tgatcctatc
    12301 aatgaactat cagcacgtcc ttgctcatga aaagcaaagc gagcatgagc ttagcagaag
    12361 ctcacgttat gtttaagagg catgtttggt ccttgttcgg ttagaatgag ctgccaatca
    12421 accctttttt atttgcttaa tcgctataaa aataaagaaa aatatgttat aattaaggtt
    12481 atgaattatc atgattatat ttgggatttg ggcggcactc tcttggataa ctatgaaatt
    12541 tctacccagg cttttattga gacgctgcat ttttttaagc tgtctgcaag ccacgatgcc
    12601 gtttatcaaa ggcttaagaa atcaacagca accgccattc aagtatttgc tcccaacgaa
    12661 ccgcaatttt tacaatatta caaagcgaat gaggctaaga aattagccaa tcctatttgg
    12721 tgcctaggtg caaaggacat tctaaagagg attgtggcat caggctcgcg taatttttta
    12781 atatcccatc gtgatcatca ggtcaatgat ttgctggagc aggctgggct tttgggctat
    12841 tttaccgagg ttgttaccgc ctcaaatggc tttgccagaa agcctaaccc tgagagctta
    12901 ctttatttga aggaaaagta cctgatcagc aagggcttag tgattggtga tcgcagactt
    12961 gatatagaag caggacaagc agcaggcttt gacaccctgc ttgttgatgg tagaaaaaac
    13021 ctattggaga tagtagatta gatggttgaa gaaaataaac aattagaaga caaggctcaa
    13081 gagtatgacg ctagccagat tcaggtctta gaggggttag aagccgttcg catgcgtcct
    13141 ggaatgtata ttggctcaac tgccaaggaa ggcttacatc acctagtttg ggagattgtt
    13201 gataattcta tcgatgaagc cttggcaggc tttgccagtc atattcaggt ttttattgag
    13261 gcagataatt cgattaccgt tattgatgat ggacgtggta tcccagttga tattcaagct
    13321 aagacaggcc ggcctgctgt agagacagtt tttacagttt tgcatgccgg tggaaaattt
    13381 ggcggtggtg gctacaaggt ttctggagga cttcatggtg ttggctcctc ggttgttaat
    13441 gccttatcca cacagcttga tgttcgtgtc tataaaaatg ggcatatcca ctatcaggag
    13501 tttaggcgtg gtgctgtagt tgatgatttg gctatcattg gaacgactga tgttacggga
    13561 acaacagtgc atttcacacc tgatccagag atctttacag aaacaacaga atttgactac
    13621 caggtcctgg caaagcgtat tcaagagctg gcctttctta atcgtggctt aaaaatctca
    13681 attacagata aacgagctgg tcttgaaaga gaagagcatt tccattacga gggtggtatt
    13741 ggctcttatg ttgccttttt aaatgacaaa aaggacgtca tcttcgatac tccgatttat
    13801 tctgatggtg agctggaggg gataacagtt gaggtggcga tgcagtacac tacaggttac
    13861 catgagactg ttatgagctt tgccaacaat attcacacac atgagggtgg tacccatgag
    13921 cagggcttta gaacagctct gacgcgcgtg attaatgact atgctaagaa ggctaagatt
    13981 ctcaaggaaa acgaggataa tctgacaggt gaggacgtcc gcgagggctt gactgctgtt
    14041 atttctgtca agcacccaaa tccacaattt gaagggcaaa caaagacaaa gttaggaaat
    14101 tctgaggttg ttaagattac caatcgcttg tttagcgaag ctcttcagcg ctttctacta
    14161 gagaatccgc aggttgcccg taagattgtt gaaaagggga ttctagcctc taaggctcgc
    14221 attgctgcca agagagcgcg tgaagtaacc cgcaaaaaat caggcctaga gatttccaat
    14281 ttgccaggga agctggctga ctgctcctca aatgatgcta gtcaaaatga gctttttatc
    14341 gtggaggggg attcggctgg tggatcagcg aagtcaggtc gcaatcgtga gtttcaggct
    14401 attctgccta ttcgtggtaa aattttaaac gttgaaaaag caacgatgga taaaatcctt
    14461 gctaacgaag aaatcagaag cctctttact gctatgggga caggctttgg agcggagttt
    14521 gatgtttcta gagctcgcta tcaaaagctg gtcatcatga ctgatgcaga tgtcgatgga
    14581 gctcatatca gaacgctttt gttaacgttg atttatcgct tcatgcgacc agtattagag
    14641 gctggctatg tttacattgc tcagccaccg atttatggtg ttaaggttgg cagcgagatt
    14701 aaggaataca ttcaaccggg agtcaaccaa gaagaggagc taaaggctgc tcttgaaaga
    14761 catagcacag gacgctcaag gccgactatt caacgctata agggcctagg agagatggac
    14821 gatcaccagc tttgggaaac aacaatggac cctgataatc gtctaatggc acgtgtgacc
    14881 gtagatgatg cggcagaggc tgatcggatt tttgacatgc tgatgggcga tcgtgttgag
    14941 ccaaggcgtg aatttattga ggaaaatgcg gtctatagta cgcttgacat ttagtcaaat
    15001 atattttgaa aagcacctaa aagtatgtta taatcgtaac gttatagtgt atttttgata
    15061 atataataaa aggcgattct tgctagttgt tcctactgaa ccggcagttg atcaatcgca
    15121 tctaaataat aaggagatta agatgtcaag cggaattatc ttgctgattg tggccatagt
    15181 cttactagtg attattgctt atttagtggg tgttattata cgcaagcgta atgacacatt
    15241 aattaccagt ctagaagaac gaaaacaagc tttatttggc cttcctgtta atgacgaaat
    15301 cgaggaagtc aagtctcttc acttgattgg tcaaagccag acctcatttc gtgaatggaa
    15361 tcaaaagtgg gttgatttga ccctaaatac ctttaccgat attgaaaagc atatctttga
    15421 ggctgagcac ttaaatgaca cctttaattt cattcgtgcc aagcatgaga ttaatagcgt
    15481 tgagagtcaa ttgaatctcg ttgaagagga tattaccgct attcgtgaag cacttggcat
    15541 attaaaggag caggaagaaa aaaacagcgc gcgtgttact catgcactag atttgtacga
    15601 aaagttgcag gcttccgttg ctgaaaatga agataatttc ggatcaacaa tggccgaaat
    15661 tgaaaagcaa atgaagaata ttgaagcaga gttttcacaa tttgttgccc ttaattcatc
    15721 aggtgaccct gttgaagcag cggaggtttt ggataaggct gaggagcata cgattgcctt
    15781 ggggcaaatt acagagcaga tccctgctat tgtagcaaag cttgaagatg attttccgga
    15841 tcaattggac gatctggaga caggctatcg tcgtttgctg gaggaaaatt atcacttccc
    15901 agaaaaaaat attgaagccc gctttcaaga gattcgtgag tctattcgtg ccaattcatc
    15961 agagctggtt acccttgatt tggaccgagc tagagatgaa aatactcaca ttcaagagcg
    16021 tatcgactca ctgtatgagc tctttgagcg tgagattgca gcctacaagg tggttgctaa
    16081 aaatagcaaa atattaccaa gatacctggc tcacgccaag cacaacaacg agcagttgaa
    16141 gcatgagatt gctcgtctat cacgtaagta tatcttgagt gaaaatgaag gcttaaatat
    16201 caaggccttt gacaaagacc tcaaagatat cgaagacaat gtccttgaga ttgctgaagc
    16261 ctttgatcag caggaaaagc cattttcaga gctacagctg attcttgatc gtagtatcaa
    16321 gacgttggct tctgtagagt ctggtcagat ggacgtcttt gctgctgtta aagacattga
    16381 aaagattgag tcacaggctc gccagcactt agaaatctac gtcacacagc ttcacatgat
    16441 taagcgttat atggaaaagc gcaatttacc gggaattcca caggattttc tgagtacctt
    16501 ctttaccact agttcgcagc tagaagcatt gatggacgaa ctaagtagag gacgtatcaa
    16561 cattgaagcg gtgtcccgtc tgtctgaggt ggcaacagct gctattgcta atctagaaga
    16621 gctaacctac caagtggttc agcatgctac cttgacagag cagctgctcc agtactctaa
    16681 ccgttatcgt tcctttgaag ctggcgtgca aaatagcttt gagcatgcct tgaaattgtt
    16741 cgaggtggac aatgactatc aggcatcatt tgatgagatt tcctatgcct tggagacagt
    16801 cgagccagga gtgacagagc gttttgtcaa ttcctatgag aagacacgtg aacgtatccg
    16861 cttctaatgt gacaagggtt gatactttat attacgaaaa agcttgaaaa agcagtccat
    16921 gctgggctat gctttttcaa gctttttgaa tggtcaggct atggcctcct tgagctatac
    16981 ccaaaaagct ggttcaagcc agtcagtaga gatagacaag gccttagtgc tattgggctg
    17041 ttgctacatg agatattttg taataaaatc agacgattat ccatttaatt aaaaaaaaaa
    17101 aaaaacgaaa ctgcggagga aacctgacga gtaactattt atggctatca atcagcatgt
    17161 tacactcttt ttggaaggcc tagcaatcac tgactgtgag gttaaccaaa gaaaataaga
    17221 tgttaaggag aatatcaatg aaaataacta aagcattgtg tgtagcaggt gctgttgcag
    17281 tcctagcctt ggcaccaatc agctcaagtc ctgcaccaac acagactgta tttgctgcta
    17341 cacgtggtac tgaagagtac tgtcataatg ggtggtgcag ttttcttgat gaacatggtg
    17401 agtggaacac gaaacgtgag ggcgaatcta atagtcccct acagcgaggt tcatggtggg
    17461 attggatttc ttattggtct ggttatatat ggtattctgt atataactgg tttaggtaac
    17521 ctctcaacgc cactgctacc atactgataa atcccttaga ctattctaag ggatttttac
    17581 tgcaaaaagc acatagggac aaggcaatac aagctccagc ctgttcttag ctccctatac
    17641 cggtaaggat cataacactc agaactccgg cagatgattg caggagctat tggagagtga
    17701 ggactagtga aagagcctct gccagaggga tttgccctta gtctttgttt gttcagcagg
    17761 cttattgtca gagggcttgt ctagtatagc cttgagattg gtttcctctt tggtgatggc
    17821 atgatcacta tgaatgatca gagcaaaagg agagacagct cctttctcat ctacaatagt
    17881 ggcagataga gcgttttgtt gggccaattt catatagtac atttgataag cagagccgaa
    17941 ttcagaggat aatttgaatg acaaggggaa ataagcctct ttgaggtgag gcagctgggc
    18001 tgtgatgtag cctttagcct tttcatgatc aacctctgtc aagggaagcg ctaagacaat
    18061 cctttcagca taggtcccta aataatagcg ttgttggtcg gggtcaaatc ggttttctcc
    18121 tgaagctccc tttaagagtc ttgtatctaa tgaatccata caatcctttc aagcatgtga
    18181 tactgtcatt atactattaa ctgcgccaaa taccaatgat aaagcattta ctaggtattt
    18241 gatcggcttt tggaagaaga tgaaatcaaa gaaaaacagc atgaaaacaa ctctcttatt
    18301 tcatgaaatt agtttttaag ttgcttaaga ccctagtttg tggtattatt aacatgtaaa
    18361 atattaaaac tcataaggag agtattataa tgtcaattat tactgatgtt tacgctcgcg
    18421 aagtccttga ctcacgcggt aacccaacac ttgaagtgga agtttatact gaatcaggtg
    18481 ctttcggacg tggtatggtt ccttcaggag cttctactgg tgagcatgaa gcagtagaac
    18541 ttcgtgatgg cgacaaatct cgttaccttg gtcttggtac tcaaaaggca gttgacaacg
    18601 ttaacaacat tatcgctgaa gcgatcattg gttatgatgt tcgcgatcaa caagctattg
    18661 acagagccat gatcgctctt gacggtactc caaacaaagg taagcttggt gctaatgcta
    18721 ttcttggtgt gtctatcgct gtagcgcgtg ctgctgctga ctaccttgag gtgccacttt
    18781 acacttacct tggaggattc aatactaagg ttcttccaac tcctatgatg aatattatca
    18841 acggtggttc tcactcagac gctccaattg ctttccaaga gttcatgatt atgccagttg
    18901 gtgcacctac cttcaaagaa ggtcttcgtt ggggtgctga ggtattccat gctcttaaga
    18961 aaatccttaa agcgcgtgga cttgttactg ctgttggtga cgaaggtgga tttgctccta
    19021 aatttgaagg aactgaagat ggtgtagaaa caatccttaa ggctatcgaa gctgctggct
    19081 atgaagctgg tgaaaatggt atcatgattg gttttgactg tgcgtcatca gaattctacg
    19141 ataaagagcg caaagtctac gactacacta agtttgaagg tgaaggcgct gctgttcgta
    19201 catctgcaga gcaaattgac taccttgaag aattggttaa caaataccca attatcacaa
    19261 tcgaagacgg tatggacgaa aatgactggg aaggctggaa agcacttact gagcgcctag
    19321 gcaaacgtgt tcaattggtt ggtgatgact tcttcgttac aaacactgaa taccttgctc
    19381 gtggtatcaa agaaggtgca gctaactcaa tccttatcaa ggttaaccaa atcggtactt
    19441 tgactgaaac ctttgaagct atcgaaatgg ctaaggaagc tggctacact gctgttgtat
    19501 cacaccgctc aggtgaaact gaagattcaa caatcgctga catcgcagtg gcaacaaacg
    19561 ctggccaaat caaaacaggt tcattgtcac gtactgaccg tatcgctaaa tacaaccaat
    19621 tgcttcgcat cgaagatcaa cttggtgaag ttgcacaata caaagggatc aaatcattct
    19681 acaaccttaa aaaataattt gattttagat taaaaggttg acaagccttg attttaaagc
    19741 attctaggac tgtcctagag tgcttttagt tttagcttca tgtcaactgt agtgggtgac
    19801 tgatagctaa gcacgagagg agacgaaggt cgccttctct ttttcaatcg gataaggcta
    19861 gggaatcccc aaatgtcgat gaagggaatt ttagaaggtt tctggaagtc gtatatgatt
    19921 tgtttccctt tgcagtgtct acacctagga gactgatagt ccagtgtagc gctgacttcg
    19981 atatgagtat cgtgctggat agtcttattc aaggtgatat tttgatcttt gattccgatg
    20041 agtagtgtgg tatgatgaat ctgttccata agacactttc taatgatggt ctggtcgctt
    20101 ttcatgataa gccttatgga actttttggg tactcaaaaa gccctataat cttcataatg
    20161 aatttaccca ttacagaaat tatagagcca atatttagag gattttagcc tattggtaga
    20221 ttgacagttt cttaagattg tgttacaatg taacacaaag aaacgaggta aacgactatg
    20281 agtacagtta ctatcagatt aaatcaagaa gaagaaatat ttttcaaaag ttacgcccaa
    20341 ctcacagggc aaagtttatc aagtctattt aaaaaagccc ttgagcggga tattgaagat
    20401 gagtatgatt taaaaatcta tcatcaagcc tatgctgaat ataaagcaga ccctgagaca
    20461 attagccatg ctgattttaa gaaagagcta ggcttataac atgtaccgta tagagtattc
    20521 taaaaaggct caaaagcaga ttaagaaagt agataagcaa attcagaggt tgctatttgc
    20581 ttggattgat aagtatttag agggaacaga taacccacgc gcaaatggca aaggtttgac
    20641 cggaaatcat gctaatgagt ggcgttatcg tattggtgat tataggctta tttgtgatat
    20701 tcaagatgat aagatggttg ttttagcgct tgagtttggg catcgtaaag atatttacta
    20761 acgttgagga agtaagatgg tcaaaaataa tgcaattggt agcaactgga aagatgtaag
    20821 agctgagtta ttcagcaagg aagaatttta gaaagtgatg ctcgtattgc tattatggac
    20881 aagtatagtt aaaaagtgtg cgtttttaat ctgtatgatg aagtaattga taaagtaaca
    20941 ggtcaaaagg ctatcattgt ctgtattgct aataaattgg tagatgattg ttatttaatc
    21001 gaaccgctaa accattctta cttaccagat tggcgtgaga taaatcagtt aattcgatat
    21061 aaaaattagc accttatcgg gtgctaattc cttgcctgct gaactcataa tttaatacct
    21121 tttttactac cccatatgtt tcccctaatt atgtgtactt gctagatata aggttaattg
    21181 ggatagaatt ttgaataaag ttgttgtatt ttgtaatagt gattgatatt gggataacct
    21241 taaaaaaata attt
//
LOCUS       DARYVE010000034        21010 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYVE010000034 DARYVE010000000
VERSION     DARYVE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21010
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(220..1320)
                     /locus_tag="TVW25_001192"
     CDS             complement(220..1320)
                     /locus_tag="TVW25_001192"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1378824.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TVW25_001193"
     CDS             complement(1317..1673)
                     /locus_tag="TVW25_001193"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1378825.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TVW25_001194"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TVW25_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1378826.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TVW25_001195"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TVW25_001195"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1378827.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TVW25_001196"
     CDS             complement(5753..6637)
                     /locus_tag="TVW25_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1378828.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TVW25_001197"
     CDS             complement(6994..10050)
                     /locus_tag="TVW25_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1378829.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEERWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYGSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGRYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TVW25_001198"
     CDS             complement(10279..12162)
                     /locus_tag="TVW25_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1378830.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TVW25_001199"
     CDS             12439..13878
                     /locus_tag="TVW25_001199"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1378831.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TVW25_001200"
     CDS             13883..14848
                     /locus_tag="TVW25_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1378832.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
     gene            complement(15225..15731)
                     /locus_tag="TVW25_001201"
     CDS             complement(15225..15731)
                     /locus_tag="TVW25_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378833.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
     gene            complement(15728..17134)
                     /locus_tag="TVW25_001202"
                     /pseudo
     CDS             complement(15728..17134)
                     /locus_tag="TVW25_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17125..17484)
                     /locus_tag="TVW25_001203"
                     /pseudo
     CDS             complement(17125..17484)
                     /locus_tag="TVW25_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17496..17762)
                     /locus_tag="TVW25_001204"
     CDS             complement(17496..17762)
                     /locus_tag="TVW25_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1378834.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
     gene            complement(17961..18413)
                     /gene="nusB"
                     /locus_tag="TVW25_001205"
     CDS             complement(17961..18413)
                     /gene="nusB"
                     /locus_tag="TVW25_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1378835.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
     gene            complement(18406..18795)
                     /locus_tag="TVW25_001206"
     CDS             complement(18406..18795)
                     /locus_tag="TVW25_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1378836.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            complement(18838..19395)
                     /gene="efp"
                     /locus_tag="TVW25_001207"
     CDS             complement(18838..19395)
                     /gene="efp"
                     /locus_tag="TVW25_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1378837.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            19578..20975
                     /locus_tag="TVW25_001208"
     CDS             19578..20975
                     /locus_tag="TVW25_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1378838.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT         6027 a         5103 c         3972 g         5908 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta acgtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgccgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaacgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtgacag actcccccta tagcaaacag
    15121 tgacccaaca aaccatcact agaagctata aggggagctt ttctatgcct aacaaaaatc
    15181 taaaatcaat aacagaaaaa cctaaagcag ttcatgcgca catactacct atctgctact
    15241 attgctctaa aagcaaccgg ctgatcggac aggttggtaa tggtgatact atagtcatga
    15301 tcttctgtca cactatattt tctcttcccc ttcaagggaa cgatgaggcc atctccatca
    15361 atagtagctc ccttgtgtcc agcttctaca ataactacac cattatcctt agtggaatcg
    15421 tatttttcaa taacctgttc tgttatagaa taccgatatc ctatcttact aagatagctg
    15481 tctgtccgtc tataaatata ttcagaccat atatcacgac cttctagctt cagtagcact
    15541 ttttcgtcgc tttctaggta taggtcagag gaatattcta tttgttcata ctttggtctc
    15601 accgcaagct ctatactctc atttggcctt agatattctt ttccttgaaa aaaatagtaa
    15661 agctcatagc gtttggagaa gatgaaaaca cctaccagca acatcattaa taacaggatt
    15721 tttcgcttca ttttgacttc ttccttttca tataaccatc tatacctgct tggatcattt
    15781 gagtatcacc ctcattgtct ccatagtgac ctgatgataa gttctttaac cactttggta
    15841 tatccttatc agaaaagacc tgggcaatct cagccgccgt ttttaaataa gtccctgaag
    15901 catctaaaaa gcctgtacca acataaccat agaggtagtt gccagcatag tcgcctggca
    15961 attctgattc ccactgtctt gaccagacag aatagttatg gccatgatag gtccttgact
    16021 tcaaatccaa gggctgaccc gtattgacaa ggtcataaaa ttgtttgttg tcaagtattg
    16081 cagcacttaa ttgacttcca gctacctgtg aaaggtaggg agcattgaca ttcactgata
    16141 ggatatcatc tcccatcttg ttgacaatca aacgaaaatt aatacccgac gattgtaatt
    16201 ttttccctag gtcttcctca atttcctttg catatttatt atttttaagg tctcactctc
    16261 catcataatt gcttctcgcc ttccaatagt catcaaaggc tgttttattg agaaaataga
    16321 ggtaatcctc ataggcagct acaagtcgct ctgatttttg tagtggcctt tcagagctgc
    16381 ttttgatggt tttaatggtc tgagtcagta tgttgtgata atggttttga gtgtactttg
    16441 aggcattgac agggctaatc ttttgattct tcaggctagt cacccagctc atatctaggc
    16501 cagcagtcga gtagctgccg tcgctgctca tgaagacctg actgagctgt gttgcgccct
    16561 gaatggctaa ccgcaaaata actaagctgt ccctaaagca gtctgaggtt tgagttagaa
    16621 accattcaag gctttccaat ttggtcgtaa catctcgaat ccctatttcc agctggtttt
    16681 tggcatggta tagtgtagag gtatcagacc aaagggtgcc atagtctccg gttaaaagac
    16741 tactgacctg cttcataaac gattcgtttt catcaatctg tgcttggatc acttgcactt
    16801 gccgttctct tagcctcttc agctcggtta agtgatcacg atccagggtt ccgtatctgg
    16861 caatctgagc atctgccctt tgataggtgg tcaactccac ttggatagca tcaatcgctg
    16921 cttgtagctt tttgatagag ggaatgatga tcgctgtaaa aagtccccta cctgctgtat
    16981 aggctgctcc ctgtagctct cccgaatcca gactagcaat gagatggtcg caaccacttg
    17041 ataacctgtc cgttatttca ttggctattt ggatattgtt tgtcatggct tgaatcaagg
    17101 cctttgactc tgctgcactg taggtcactc ccatcgtaaa cggctccttt caccgataag
    17161 ctcttctttg tccctctcta gtctacgacg aacccccatc gtatagattg acacgtgatc
    17221 cagatgctca tcaacatagc gatccatttg tctgatcaag tggtcattgg cctcttgctc
    17281 tgcgtacttt ccagcttagt cctcaggcat atggttcaat agggactcaa gggcaaaaga
    17341 gaggtgctga cagtctgctt gaatctccga gactgcttgt tcatgccgtc gtttcatcga
    17401 caaaagatcc tcctctagcc actccagctc attgatctgt cgggttaggg caagaaattt
    17461 ttcttcagat tcttctttga tcatgactta ttcccctatc ttgttgcttc ctctaggtct
    17521 cttttctcta atttggccgc aagctgagga aatttattag cctgaataag gactgcctga
    17581 ctaaagtcgc tgacagcctg cagcagttga ttagagacct gacgtccctt ttccatacct
    17641 gcaataccct tggtcacact aaatgcaacg gactgttggt gaaccctact ggtgtctaca
    17701 cctaccaatt cactaatagc agcagaagca gccacagggc ttgatgtaat ggtatcactc
    17761 atacaatttc tcctttataa cccttatgtc ttttattata tcacaggata atagccattg
    17821 tgcttatagc tcttacctaa ataatagcaa ctgatgaatc tttttgggaa ttcattgaca
    17881 tagccaacca gatgagacgt ttttgagcat tcaaaaagcc ctatagggct ttagtaactt
    17941 aagaagcttt caccagcttg ttattctgtc actgcagctg actcatcaga aacaaactga
    18001 ctgagtaagc cattaataaa cttagctgag gtatcatcag aatatttttt agcaatttca
    18061 atgatttcat ttaaggctac acgatcaggt gtctcctcaa acagggtcat ctcaaagagc
    18121 ccaagacgca acatcgtctt gtctaccact gtcaagcgct caatggacca gctcgtttta
    18181 aggtttttct tgataacctc atcaagctca gccttatgat ccataacgcc attgacaaga
    18241 tttaacagaa aaacaggaag ctcagaaggc tgcttgtcat cagctgcttc cttgtcatag
    18301 tcataggcaa actgtgaggc aggcagaaaa tctccgccca tctccatagc aaataaagct
    18361 tgaaaagcac gctcacgcaa atctcttctc gaatgttgaa aatgcttagt catccaaaaa
    18421 atcctcatca aacaatgatt tcatttctgg ctttggtgtc ttttcaggaa caatcccctc
    18481 aacatggata ttaacataag aaatggtaac ctcagccatg tcataaacag ctgacttaac
    18541 agccctttga atagccattg acaccgcagg aacctttaca ccatattgca ggtaaacata
    18601 gatgtctgca ttgactgttc cattttcttc cgtctgaaga tagacgccct taccaagact
    18661 agctttatta aaggtatctg ccatgttttt attgtgaagc gagtgaacac cctcgacctg
    18721 catcgtagca attcccgtaa taacctcaag aactcgtggc gaaataacaa tttcaccgat
    18781 attttcagtt gtcatagcat ttcctttctt tctcttagac taattccgga aagcgaatta
    18841 agcgcgagaa acgtaagtcc cctcagcagt attgatgatt agcttttgtc ctacctcaat
    18901 aaagtctgga acgtttacca cgagtcctgt ttcaagggtt gcaggcttac cagagcctgt
    18961 aacagttgct cccttgattg atggctgggt ctctgtaaca gtcaactcaa cagtagtcgg
    19021 tacctgaact ccgatcacct ctgttccata aaactggatt ttcacatcag agttttcaag
    19081 gatatataat agctcttgct caacattggc tactggaatc tcatactggt cataggtttc
    19141 agtattcata aagtaagcag tctcgtccat cttgtaaagg tattgagccg gcactgtttc
    19201 gataatagcc tgttcaaact tttcgtctgg acgataggtt gtgtcgaatg tagagccagt
    19261 acgaacatca cgcaatttca tacgcatgat agtgtttccc ttacctggct tatgatggct
    19321 tgcttcaagt acgcgaatta gctttccttc tgcttcaaac gtcatacctg ctctaagctt
    19381 gcttgcttca atcatttgtt attacctctt actaaaatag ttatcgtctt attttaccac
    19441 aaaagagctg taggctcaaa tgttttatga ccattatcag cccttgttat cattcgaaag
    19501 tgataatgtc ttagctaggt cgaatgtgaa aatgtcccgt ctgttaaact agaaagatga
    19561 ggaaaataga actaactatg atagagtcaa agaaatacct agtcatcaaa gctgtttgtg
    19621 agggtaaaaa acagaaaaac agggcttgtg tagaattagg gttaagcaag aggcaggtga
    19681 accgattgat actagcctat cgagagaaag gaaagtcagc tttcgttcat ggtaatagat
    19741 caaaaagacc aactcatgcc atgtctttag aaacaaagag aaggattatc gagaaatatc
    19801 aaagttacgg tgatttaaga ccaaatgttg ttcatttctg cgaactacta gcggaagaag
    19861 aaaacatcgc ctattcagat acaactgtta gaaaactact ctaccaagca gggtttctat
    19921 ctccaaagac tcaacgagca acgaaaagac gattgaaaca agaagccaaa caaaagaaaa
    19981 gggaggcaga aaaaagagga tccaaactcc caactgcttc caacttcttt gaagaacctg
    20041 acaaagctca tcccagccga gcaagaaaga aattcaaagg ggaactcatt caaatggagg
    20101 ccagtcaatt cccttggttt ggacaacagg aaacacatct tcatgtcgct attgacgatg
    20161 cctccggtga tattgtcggg gcttactttg atactcagga gacgctaaac gggtattatc
    20221 atgtcttaga acagattcta gaggtacatg gtatcccttt ccagttcctt actgataaaa
    20281 ggactgtatt cacttatgct tccagtcagt ctaaaaagat cgaggaagat acctttacac
    20341 agtttggata tgcttgccat cagcttggta ttgccattga aacgtcttct atccctcaag
    20401 ctaaagggcg tgtagaacgt cttaatcaga cccttcaatc gcgtctacca attgatttac
    20461 agaggaatca aattaccagc atctctcaag cgaatcgtta tcttaagaga tggattaaac
    20521 gatttaacaa gcagtttggt ggactggcca gtgagtctgt ttttgagaaa gcacctaaac
    20581 cggcccagcg aaacctactg ttagcgagaa tctctgaaag agtaattgat agtgggcatc
    20641 atattcgata tcaaaacaac ttctacttgc ccgtcgaagg ggataaaaaa atctatttta
    20701 cgcgtaagac aaaggcactt gtgattgagg cattcgatgg agacatctac cttaatatcg
    20761 cagacaatat ttatgccact agaaagttac caaaacacga gaagcactcc aaagaattcg
    20821 aaatggtgcc taaaactaaa aaagaaagac gcaagtatat tccaccacaa tcccatccgt
    20881 ggaaacttgc atctttcaaa caataccttc ataaaatcgg aaaatcttat gaagaattca
    20941 agcgtgagag gaatacctct caaccacaat tataacagat ttttctctta tctaaccgat
    21001 tttttcaaga
//
LOCUS       DARYVE010000035        20809 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYVE010000035 DARYVE010000000
VERSION     DARYVE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20809
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            40..1455
                     /locus_tag="TVW25_001209"
     CDS             40..1455
                     /locus_tag="TVW25_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1378839.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            1657..5408
                     /locus_tag="TVW25_001210"
                     /pseudo
     CDS             1657..5408
                     /locus_tag="TVW25_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            5637..6542
                     /locus_tag="TVW25_001211"
     CDS             5637..6542
                     /locus_tag="TVW25_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1378840.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            6526..7410
                     /gene="isdE"
                     /locus_tag="TVW25_001212"
     CDS             6526..7410
                     /gene="isdE"
                     /locus_tag="TVW25_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1378841.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            7412..8434
                     /locus_tag="TVW25_001213"
     CDS             7412..8434
                     /locus_tag="TVW25_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1378842.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            8431..9213
                     /locus_tag="TVW25_001214"
     CDS             8431..9213
                     /locus_tag="TVW25_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378843.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            9259..11022
                     /locus_tag="TVW25_001215"
     CDS             9259..11022
                     /locus_tag="TVW25_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1378844.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            11015..12697
                     /locus_tag="TVW25_001216"
     CDS             11015..12697
                     /locus_tag="TVW25_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378845.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            12678..13271
                     /locus_tag="TVW25_001217"
     CDS             12678..13271
                     /locus_tag="TVW25_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1378846.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            13268..13948
                     /locus_tag="TVW25_001218"
     CDS             13268..13948
                     /locus_tag="TVW25_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1378847.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            13885..15339
                     /locus_tag="TVW25_001219"
     CDS             13885..15339
                     /locus_tag="TVW25_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378848.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            15703..17718
                     /gene="recG"
                     /locus_tag="TVW25_001220"
     CDS             15703..17718
                     /gene="recG"
                     /locus_tag="TVW25_001220"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1378849.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(17838..18803)
                     /locus_tag="TVW25_001221"
     CDS             complement(17838..18803)
                     /locus_tag="TVW25_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1378850.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18875..20263
                     /locus_tag="TVW25_001222"
     CDS             18875..20263
                     /locus_tag="TVW25_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1378851.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(20549..>20809)
                     /locus_tag="TVW25_001223"
     CDS             complement(20549..>20809)
                     /locus_tag="TVW25_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1378852.1"
                     /translation="AKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIPDKEEVD
                     LIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
BASE COUNT         5567 a         4138 c         5082 g         6022 t
ORIGIN      
        1 taggttagaa tagagcagaa agaagtgatt gaatactaaa tgagaaaaaa taaattatta
       61 agaatgataa tgctgatgac tcttctggta cctcatttag agaccgcaag agtattggca
      121 gaggatacag gagctgaagc cagccaggtt ccagctactg ctaatgaggc tgcaatcgcc
      181 cagactggtg agtccacttc gacagcagct gctacctcag ctactgacaa ctcctcatca
      241 accactgaga ctactcccaa cagtggagaa cctggagcaa cggggtcatc aagcaataca
      301 gctagctctg gatcagcttc tggttctact ggacagtcga cacctactag tccagcagct
      361 agccctcagc cagcccctga agttgctaca caggcatctc agccggcact gaatattgtt
      421 cctgctgctc ctacagttga tttgtccttg actctggccc tgccttctgt aaatacctat
      481 gctgcttatg tgacgcattg gagtggtcag agtgcttata cccataacct cttgtctagg
      541 cgctatggga tcaaggcaga gcagcttgat agctttttaa agtctaccaa gatcaagtat
      601 gatgagaagc gaattaacgg tgctgccttg ctgcaatggg aaaaaaagag tgggctagat
      661 gtgcgggcga ttgtagccat tgcaatgaca gaaagtgagc taggaaccaa gggaaatgca
      721 accttactag gctctaacat gtttggctat gcgctttttg accttgattc gaaaaagcca
      781 aatcagttta atgatgagct tgctattgtt aagctgacac aggagacgat tatcaaaaat
      841 agcaacctta attttgagca gcaggatcaa aaggctgata aatttgccaa aaagcagttg
      901 aactttgcta gtgatggtgg tctttacttc acagatacca atggcattgg caagcgtcgc
      961 gctgagatca tggaaaaatt agatgcttgg attgatcagc atggaggcac gccagagatt
     1021 ccggctgagc tgaaaattca atcctcttca agctttgctg ttgttcctac aggctacaag
     1081 ctgtctaaga gctatgatat tttaagctat caggcgtcaa gctatgcttg gggacaatgt
     1141 acctggtatg tttataatcg cgctaaggag ctaggctatc agtttgattc ctttatggga
     1201 aatggtggtg actggagatt taagtctggc tacagtattt ctaaggagcc aaaggtaggc
     1261 tatgcggttt cctttgctcc aggtcaagcg ggtgctgacg gtctttatgg gcacgtctct
     1321 attgttgagg atgtcagaaa ggacggctcc atcctgattt cagagtcaaa ttgtcttggc
     1381 ttaggtcaga tttcataccg cacctttact gctgagcagg ccaaccaatt gacttatgtt
     1441 gttggaaaat cataagtaat cttcttgctt taaaggcgag aagtacagaa tttttgtaag
     1501 aaaaaatcca gctctgttgc agggctgttt ttttctttgc tttattgtga aaaaaatctc
     1561 aaattcaatc ttgacaaagg cttgacaaca taataaatta agtgagatta ataaaataat
     1621 taaatggcta ataacatttt tagaaggttc gaaataatga aaagtatcaa taagtgcgcc
     1681 attcttgctt tatcaacgct ggctcttgcc cagtctgccc agacggttcg ctcagaggct
     1741 actcaagtct cttcaagtct tgtgacgact gtcaagctta aggataatat tttattgttc
     1801 gaggagatcg gtccctatgc ggacaagtca gaggggaagc tctattataa aaatatcgag
     1861 aaaattctca ttgatggtaa agagtatgac aaaaagctgg agggtgacta tagctatgac
     1921 atcaattacc aaggaatcaa ggtaaacgct aagaacatca cagaaggaca gcatcagctg
     1981 cgcatcgtca ataagactaa cggaggcatt cttgtggtct ttgacaagaa aggaaatgat
     2041 gttacctttg tttctgccaa gccttcagat gatactactg cttcaccgca gcaagctgct
     2101 gctaagacag aaaagcctgc taaggtaact agccatgatg gcttagcgac cctatcattt
     2161 atcaccaaac tagagacaac agaaggagag cttctttttc cggaaattga tcgctattcc
     2221 agcaccaagc aaattaagga attagctcat caaatcacaa agatcaaggt caatgaccag
     2281 gactataagg atttggtcta tgattcagta aaggacaagc ctggctatgt gtctgacctg
     2341 aaggggcttc atcttgggac gacagctttc aaggagggag aaaacaaggt tgtcatttcc
     2401 tcacaaagct ttgaagatgt catcattaca gtgaaaaagt caggggagca atacaccttt
     2461 gtttctgcta agcaaaagca gagacaagga tcccagcagg aagcaccgca gggacttgat
     2521 tttactaagc tggaaagcgc gatcaaggaa gctgagcgta tcattgctag cgaggccaat
     2581 aaagaacagg tcaaggactt gtctagcaag cttcaggtga tcaaggagtc ctatcgtcag
     2641 attgacaatg aaaaattgct caaggagacc tatgagcttt tgatggatag tatcaagtcc
     2701 tatcagggaa ctgatctggc tgttacggat ctaaaggcag gaacctatac cttaaccttt
     2761 aaggccaata aggaaaatac agaggaagcc tcaatgctgc agggagcatt tgataagaag
     2821 gccaagctgg tcgtcaaaga agatggcaag atggagattt cattgctcaa tacagctcta
     2881 gggcaatttt tgattgactt ttccattgag agtaaagggc agtatccaac ctctgtccgc
     2941 actcaggttg gtgaacgcga tattaacaat aactacatta gagtgaattt accctaccga
     3001 ttgaggagct ggacaagctt cacaagggtg ctgtgctagt atcagctatg ggtggtcagg
     3061 aaagcgacct acatcactat gacaaataca ccaagttgga catgaccttt agcgctacag
     3121 caagtaaggg ctggacaggc tatcaggctg agattgacga caaggaaaaa ggggtcggct
     3181 ctgagcgtct tgaaaaggtt ttggttaagc ttggtaagga ccttaacggt gatggcaaaa
     3241 tgtcacctga ggaaattgcg aagattgaag gtgagctgcg cctagaccac tatgatttga
     3301 cagatatttc actcttaaag catgctaagc atattactga gctgcactta gagggcaatc
     3361 agattgcaag cattccaaag gaaaccttca gtcaaatgac caatctaagg ttcttaaatc
     3421 ttcgcagcaa tgtgattaca accctagata aggatacctt tgctcataac agccagctaa
     3481 aagagctcta tctctcaagc aactatatgc caaatctgga ggaaggacta tttagaaatc
     3541 ttggtcagct ggatcagcta gatctgtcaa aaaatagaat cagcgtgatt cgagatggtg
     3601 tctttaatgg tctatctcgc ttgacctcct tggccttggc tgaaaatatc attactgaat
     3661 tttcagaaaa tgctctagct tcacttgata atctaaactt ctttgatgtt tctgaaaacc
     3721 agttgggcag cctgccaagc tccttgagta agctaactaa gctttcttat atcgttgcca
     3781 atcgaaacca ggttttagat attgctaata ttgactttag tcatatgcca aacttattaa
     3841 ccgttgactt ggcatcaaat gagctaacta aaatcccaca gggagccttc aaggctaata
     3901 agcagctatc aaagcttaat gtctataata accttttaac gaatattagc gaagctgatt
     3961 ttgcagatct aaaggcattg gatcttgatc ttaagtttaa ctgcctaagt ggcgttagtg
     4021 ataagcttag acagatcatg ggaacaaata agctaaaccc acaaaagcaa tttgctaatc
     4081 tatctgcgac tttaaatcat caagcgatga cctatcacca agggtttagc ctgcttgatt
     4141 tgtattattg ggagcagcag acactctcaa gcaccgaagc agaaattagc tctgttgagg
     4201 attacaataa acgccttaag gcaagctcgt cagacatcat tgccttatta aatgagcgtt
     4261 atgctgactg ggatattgtg gtgcaattgc agaaaaaaac atcaaccggt caatatgtca
     4321 ccgttgatga gagacgcttg aataacgatc cacaagatga gcttcaaggc tcctttgacc
     4381 taaagggagc aggtgtttat cgtgttcgta aggctcttat caccaaggaa tttgctaaga
     4441 agcgtgagca tatttatctg acctctaatg atgttgaggt caaggaggat cagcttgcag
     4501 gtagtgacca gtctaagggc ttggatatta ataagcttga agatggtgtc tactacatca
     4561 aggcaagcat gcttaaaaat gatttgcagt cagaatcaat gtctcatcag gctattgacc
     4621 accgcgtcaa attgattgtg aataagggtg tctatagcct agaggtgacc tttaagggca
     4681 tgaagatcgg taacctgaca gggtatctcg gagagttgag ctactttgtt gatggctacc
     4741 aaagggattt gactggcaga ccggttggta agacagaaaa agcagaggtt gtgtcctact
     4801 ttacagatgt cacaggcaag cccctgtcag acgcttatgg cagcaattac ccacaggtgt
     4861 tgagatttag gctgattgat caggctaaaa aggatggctt ggtacctctt cgcgtctttg
     4921 tgccaattat ggacgctatc tctaagggaa caggcttcca gacagtcttt atgaagttgg
     4981 atcttcaaag cctgacaaag gataaggcac aattgccaca ctcagaggac aatcagggac
     5041 atggtaccat aggtgagctc ttgcagcctc acacaggtat cattggtggt catacaagtc
     5101 ctgctattcc taatttgacc aatcttttga ctaagaagtc agctgctcca agcagtaatg
     5161 ccaaggagga cgctaagacc ggtacagata agcttaagag cctgatttct tcacataagg
     5221 cgtctaaggc tggtacaggc aaggcctcta agcaggctgc taagactaga gccaaagcta
     5281 aatctaaggc tgctaaacat agtcaggagc agatgaaagc tgatcatcgc ggccatatca
     5341 ttatcggtct agcaagcttt attgtcatag cagttggtct cattcttggt aggaaaaaat
     5401 tattttaagt cagtagagag tctgtttgat gcactaagag cttggtttaa tcgcttgtag
     5461 tcatcaaggc ttatcaacga tacgtaaagg catgcctgtt tctaatgatt tcttaagctt
     5521 acccttggta agtgaggaat gggtatgctt ttcgtatttg aggtgttata atagtcaaat
     5581 aagagtaggt cttggcctgc gtctaaatct atgccttatt tgattgtcgt aaggaaatga
     5641 agatcattaa tgaggaacat atgataaaga gattattcaa aaaattaatg ggtggcttgg
     5701 tggtattgct ggtttgccta gcagctatag gaggtaaggc ctatgctgat aagggtgagc
     5761 tttattcctg tgtgattagg cgagattatc gtcacccggt ttcagggcaa attgaagata
     5821 gcggtggtga gcacgctttt gagattggcc aaggtatggt ggaaggaaca gtttatagca
     5881 atggtatgct agaggtaacc tcggctgggg atttgtatct gacctttcgc atgagtctag
     5941 ctgatttttc aggtaactac caattttggg ttcagccggg tggtacaggg gcttttcagg
     6001 cggcagccta cagtgtcacc aaggttggca ctgataccaa tggcacaaca aaggatattg
     6061 cgattgcttt gcctgatgtc aatacggttg ttagaggcag catgtacgta gagcctatgg
     6121 gcagagaggt tgtcttttac ctgtcaccat ctgagctaca agaaggctac agtggagata
     6181 tggtagctag ctttgcagca ggagaagcca agacggatca tgcggtgaca gctcctgcaa
     6241 aggcagatga gaagaaagct cctagtaaac cggactcaaa agacgccaag tcagctccta
     6301 atccctcagc aaggccagtt ggtcaatcaa gcagtcccaa aaaacagtca aatccctcta
     6361 agaagggtca ggcagttggt ttgagcactt cgctagataa aagtaagcaa gagtcgtccc
     6421 aaaagccagt aaataatcca ttgccagttc tggtttacta tgtaccaaca gctcttttgt
     6481 tgtcaggagc cttggtcttg tttataaaga aaaagagaaa aaacaatgaa gaaagtcatt
     6541 aagcttattg gattagctgt tttgtccttg gtgctatctg cttgtgtgga tcagcaccct
     6601 agggcagaga aaaaggctga taaggagaga attgttgcca cctctgtggc tgttgttgat
     6661 atttgtgatc ggctaagcct agatttggtt ggggtctgtg acagtaagct ataccaattg
     6721 ccaaagcgtt acgatgctgt caaaaggatc ggtctgccga tgaatcctga tatggaggtt
     6781 attgcttctc taaagccaac gtggatactc agtcccaatt ctctgcaaaa tgatttagag
     6841 cctaaatacc agcaattgga tacggaatat ggctttttga atttaactag ccttgaaggc
     6901 atgtaccagt cgattgatga tttgggggac ttgtttgatc gcaaaaagga agctaagcgc
     6961 ttgcgggctg attatgagga gttttaccgg gcctttaaga aaaagcataa agggcaaaaa
     7021 aagcctaggg ttcttatttt gatggggctt cctggcagct atctgattgc tacaaataaa
     7081 tcctatgttg gtaatctgct tgagctggct ggtggtgaga atgtttatca ctctgaggac
     7141 aaggaatttt tgtctgccaa tccagaagac atgcttcagc agcagcctga gctgattttg
     7201 cgtactgccc acgccattcc agacaaggtt aaggacatgt ttgataagga atttgctgaa
     7261 aatgatattt ggaagcattt tgaagctgtc aagtctcagc aggtttatga tttagacaat
     7321 accctttttg gcatgagtgc taagtttaac tacaaagagg ctttgaacca tctgtcacaa
     7381 atcttttatg gagcaaagga agtcaagtaa gatgcagcaa ggtagtcaat attctgatca
     7441 agtcacagca gcaagaaaaa ggaccactag actggtctat atggttctat tgctcatgct
     7501 gctgtttggt ttaatgctat atgcggtctc tgttgggggc ttatctgttt cttatcagag
     7561 gatctttaat ggcttatttg tagcatatga ttcagaggta gcccttattt acgatttacg
     7621 ctttccaagg attgtgattg ctttattggc tggggcgggg atagcaacat ctggggtctt
     7681 gtttcaggcg attttaaaaa atcctatttc agatccggcg attattgggg tttgcagtgg
     7741 ggctagcttt atggtcttgt tatctagcct gcttttgccg cagctcttgt tttatggtcc
     7801 tttgttatca tttgtgggag gctgtgtttc ttttttgatg atttatacct tgtcctggaa
     7861 gaagggcttg cagccgatac gcatcatttt gacaggaata gctatcaacg ccttgttttt
     7921 aggcttgtct cgtgcgatta ctgatttttc aaaaaccagc aatccctttg tcaatgcgct
     7981 gttgtcagga aatattagtc aaaaaacctg ggcagatgtt ggtgtgctgt ggccttatac
     8041 agtgcttggc ctgctgcttg cgataggcct agcaaggcag tgtgatctac tgctgctaaa
     8101 cgatggcttg attcgtaatt taggcattga tagtaattac ctgcgcttag gaatctcgtt
     8161 ggttgcggtc ttactagctg ctgtttccac ctcgattgtg ggtgtggtgt catttttagg
     8221 cctgattgtg ccgcatattg gccgcctttt agttggcagt aagcatagct atctcattcc
     8281 tttttctgcc ctgcttggcg cctttgtctt tttgctggca gataccttag gaaggcagtt
     8341 gtgttatccc ttggagatta gcccagctgt tatcatgagc attgtcgggg gaccttattt
     8401 tatttatctg ttaaggaggt ctgacgtgat atgagtcatg agcaaggctt gattcgtgta
     8461 gaggatttgt cctttactta tcgtgatagg cctattttag ataggctgag ctttaccatt
     8521 ccaaaaggca agataacgac aatcatgggg gcaaacggct gtggcaaatc aaccctacta
     8581 ggtctgctga ctaaaaatat ccccgttaag tctgggcaaa ttttcttaga gggacaagct
     8641 attagctcta ttagtcttaa gcagtttgcc caaaaagtag ccgttgtgca tcaggataat
     8701 caggcggtag cagatcttct ggtgggtgat ttggtggctg tggcaagcca agcccatcgg
     8761 cgttttttta agggatcaag tcaagaggac gatgacattg ttgcttgggc cttagaggtg
     8821 actaatctaa gggaattggc ctttagggaa atgcaggagc tatctggtgg tgaaaagcaa
     8881 agggtctgga ttgctatggc gcttgcccaa aaaacaggtg tcttagtgct tgatgagcca
     8941 accacttatc ttgatattaa gtaccagctg gacattttag ccctcatcaa aaaaatcaat
     9001 caggagctag gaatgaccat tatcatggtg ttacatgata ttaatcaggc cttggctgtt
     9061 tcggattgtg tgcttgggct gcaaaaaggt gccatctatg cccaaggcag tccacaggag
     9121 gttcttgatc aggcttttgt ggaggcggtt tttggggtga gcttgccctt tattgaaaag
     9181 caggataggc gatttgttct taccacttta tgagacaaat aaaaaatgaa tgatagatag
     9241 gaataaggcg acgattatat gaacgataca actgaaaaaa tatcacgcgc aaagaaaaaa
     9301 atgcttttaa ggcgtttaaa ggagcgtatt gctcctaagc gttttttgct ttatgtgtcg
     9361 gcctttttat cttggctgca atttttgatg cgtttaatga gcttttactt aattgctaag
     9421 caattcacag cctttttagc aggtcaagcc ctgcaattga caaggctgct tgttatcctt
     9481 ttgattttaa atgctgttgg ctttggcttg gcgatgattg caaagcagct gcagggccta
     9541 gcttcgcaat ttgcgcgtga ctcgctcaag caatcctttt ttgatgcctt tattgctatg
     9601 gacgggcaat ttgatcagca gtcaacagag gctgatgtgt taacggttgc ctcacaaggg
     9661 attgatagct tggataccta ttattcctat tacctatcgc ttgcaatgct aacagctttt
     9721 aattgcacaa cggtcttact gcttgttttt ttgatctatc ctataggggg cttggtcttt
     9781 atcttgtctt tgcccttgat tcccatatcc attgttgcta tgcaaaaacg ctctaaaagg
     9841 atcatgaacc attactggtc aacctatatg gacgttggca atctatttat ggacgatctc
     9901 aaggggctaa atacccttta ttcctatcag gcagatgaaa ggtatgagga aagctttgtc
     9961 aataaggcag aggcctttcg taaggctacc atgcagctct tgggctttca gctgcaagcg
    10021 gttggctata tggacgctgt catgtatctt ggcattggct tatctggctt tttagcggtt
    10081 caggctctgt cagctggtgg tatatccttt tttgactttc tcttttttat cctgattgca
    10141 acggaatttt ttgcccctat tagggagcag ggctatggca tgcacctagt catgatgaat
    10201 actaaaatgg cagatcaaat ctttggcttt ttagatagcg ttgaggctgt tgaccaagac
    10261 aagggagttg ccttaccggc ctttgatcgt attgatattc aagatttgtc cttttcacat
    10321 ggggaaaagg ctttgctaag agacatcacg atgactatca aaaagggtga gctaacagct
    10381 gttgcaggtg tttcaggaca gggtaagact agtcttgcac agctcctgtt gaagcgctat
    10441 caggcagata gcggtcagat attccttggt gatgtgacga ttgatctggc ttctaaacag
    10501 gccatcaatc aggaaatact ctacgtttct gaccagtcaa cgctgcttaa tatgagtatt
    10561 tatgagaacc ttgctatggc agctcagctg actagaaagg agctgcttag ctggattgat
    10621 gagcatggca ttttgagctt tatttactgg ctacctgatg ggattgatac cattgtaggt
    10681 gagaatggct gtcacttatc tgcagggcaa agacagcagg tgatttgtgc tagggcctta
    10741 ttgagccagc gttcctgtta tatttttgat gaggctacct caagtcttga tgctgagaat
    10801 gaagctgcta ttcacagact gcttcagcaa ttggctaaac aggccattgt aattgtcatc
    10861 actcataaga tgaaatattt gaagcaggct gatcaggtgc tctttttaag ccctgagcag
    10921 tctgctagct tggctagccc aagagagctt taccgccatc atttggccta tcgtcaatta
    10981 gttgatacac aagtagaatt ggaggcaaat ctttatggtt aagagtgatt acagcaccta
    11041 ccggctagtt ttacgattgc ttgctatgat gaagcatttg ctggcttgga tagctctggc
    11101 ggtgatgttt gcagtgctgg gctttgtgct taccgttggc attcctacca gcttagccta
    11161 tctgggctta gaggtgatgg ctggtcatgc tattaccttt aaatggcttt atctatttgt
    11221 tgctatggca ctgctaaggg ggcttgttcg ttatggagag cattattttg ggcattttgt
    11281 tgcctttcat agcctggcag cctttcgcag gattgtcttt aaaaagctaa gagcactctc
    11341 gccggcacgc ttagacagtc aggacagcgg gcacctgtta aagatgattg gcgaggatat
    11401 tgaggccttg gaggtctttt ttgcccacac gcttgcccct atttgtacgg cgtttatttc
    11461 agctagcttg atggcctatt acctttggca ggttagctgg aagttagcct tgggggctat
    11521 tgtgacctat gtgcttttgg ctgttattat tccagtgtat ttttcaaacg tccttcaatc
    11581 actgctcaaa aagcaaaatg aagggcgcag ggcttatgtg tcaagctttt tagagagtct
    11641 cagatctgtt aaggatttgc tgcaatttca aagcattgag aagcgcttta agctcttatc
    11701 caatcagagc aagcatgtta atgcgcttga tcgtcaggtg gcacaggctc aatttttaca
    11761 aatggcgata acctttttgg ctcttggctt gtctattttg acctttgctt atgttactct
    11821 ttttgagctg agtcagcaga cggtgacgtt tgctggtggg ttgctggctt ttgttgcctt
    11881 tacagcctcc tttgcaccct ttttagaatt ggggcgtttg ccgcttggct tcaagcgtgc
    11941 catgaatgct gctaggaatg tctttcagct tttagatgaa gaagcgttag tagataaggg
    12001 agatcagcgt atttcctcgg taacaaggat tgctgttgag gatctgacct ttgcttatcc
    12061 caagcatcag gagactattt accaccactt atccgtcgct tttgaaaaga aaggcattat
    12121 cggtattcag ggagagtcag gctctgggaa gtcaactctg atgaagatca ttatgaaatg
    12181 gtacaattgg caagctggtc atattttcct gagtgaggtt gacagtcaaa cgctaaatgc
    12241 tgcttcccta caggctaact ttgcctatgt cccacagaat gcgcagctat ttcagcaaac
    12301 acttcgtgac aatatcacac ttggtcgtaa ggacatttca gatgatgata tcatggaact
    12361 tgctgaggcc tgtggcatga aggagcgtat cctagcctgt gatgaggggc tagataccct
    12421 agtgagagga tcagcagact tttcagctgg tgaagcccag cgcttggaat tgatgcgggc
    12481 tctattgaag cgggcggatt gctatatttt tgatgagcca acatcaaact tagattcgct
    12541 gaatgaagcc atctttattg atttgattaa aaagcattgc cggggaatgg tctttttgat
    12601 ttcacatcgg ccatccacct tggcctgtgc agaccagcta ttttgtgtga gaaatggttt
    12661 tttgaaggag gtaaacaatg aaagggttaa ccattaaaga tatcatgaca acaggcgcct
    12721 ttgccgccct ctatttcgtt tgtgtggggc taggagccat gctgagcatt ctgtttgatc
    12781 gctcaggcaa tatgctctat gcgccagcct ttgcggcctt gcttggcggg ccagtttata
    12841 tgctattaat cgctaagctg cagacctttg gaccgataag cctagtagga attattatgg
    12901 gaagcttttt ctttttgaca ggtcattttt ttgcttcaat gctaccagct attctttttg
    12961 gctgtttggc agatggcata gcccttttag gaaaatatca atctagacta gtgaatctct
    13021 tgtcttatct tgtttttgcc tttgttaaca gtggtcctat tattttaatg tggctgttga
    13081 aggacgccta tatccagagt cttttagcgc gtggtaagga catggcatat gttaaccgta
    13141 tcatgtatga ctttaccgtt gcaaatgtca gctggtttgt tggtgttgtc cttctttgtg
    13201 ccttagtagg tggccttttt ggtcaatacc tgctgaaaaa gcattttgct aagtcaggaa
    13261 tgcttttatg aggcttgatg ttcgcacaaa attgctcctg ttaattctag ccaatgcctg
    13321 cttctttttt cggattgatg gctggctggg gacgatgatt ataggtgttt tgcttggcat
    13381 tttgttttgg cttggtcaag ggcgtctggc aatcggtatg acactgctct atgccttact
    13441 gcttgctttg tctgtattgc cgcttcatgt gctgccagcc tatctgttta ggctgctgag
    13501 ctttgcagct gttgctggtc aattgcttta cccatctgtg cttgctgctt tgatttttgt
    13561 caagacaacg actgcctacg agcttgtgca tgggctgcga aaatggcatg tgccagaggt
    13621 ttgtctgttg actcttgctg tcatgctgcg ttttttacct aagatcaggc aagaaggaaa
    13681 gattattcgg caatctctga aaatcagggg cattttcttg gacagctggg ctattgtcag
    13741 acagccaagg cggtatatgg agtatctctt ggtaccgctg ttgatgtcat tgctgagaag
    13801 tagtcaggac ttaaccattg ctagcctaac aaaagggcta gcaatcaaaa agggagcaag
    13861 tgagtgcttc gtatcacatc tatcatggaa ggattggggg gtacagattt ggatatttgt
    13921 gacgatagcc tacatggttc tccagtgatc aaggcaaagc agctgcagtt ttcctatacc
    13981 aatcgtaggc agactgcctg tgagctcagg gattgtcaga tagaggcagg tcaatttatc
    14041 gtgctttgtg gtcagtcagg ctcaggcaag tcaacctttc ttaagctgct caatggcttg
    14101 attccagact atttttcagg acaattacaa ggaagtctga aagtactgtc tcatcaggct
    14161 ggtcaggcta gtgttgaagt gctgtcaagg caggtttcct ctgtctttca aaacccagcc
    14221 agccaatttt tctatcgtga ggtcaagcat gagcttgttt ttccttgtga aaatcaaggc
    14281 ttagagccag ctcttatcct tgagaggctg gataccttgg cagctgattt tgacatcaag
    14341 gacttactag aagcagatat gcttaagcta tctggtggtc aaaagcagcg ggtggctatt
    14401 gcagcagcta tcatgcaagg gacagctatc atggtttttg atgagccaac agccaatttg
    14461 gaccatgcta gtgtagcagc ggtcaaggct tatttaaagc agcttaaggc tgctggcaaa
    14521 accattattg tcgctgagca ccgcttgcat tatttgctgg atttggcaga ccatttttac
    14581 tatttttcag ctggtaggct agagcgcgta ttaagcccca aggatctgct agctttgcca
    14641 gatcaggaac gtgaggagct aggactaaga cgatgtgagt tgactgctgt gactaaggct
    14701 ttgcgggcaa aaactgtttt tgagcattat gatccagagc atgccttgca aatcaagcag
    14761 ctagaggtca aggcaggcag cagggttttg tatcacctca atcagctcag ctttggtgca
    14821 gggcaaatca ctggcattac cggagctaac ggtttgggaa aatcgcagtt ggctttatat
    14881 ctggcaggta tttttgaagc aaaagaggcc aagatcagct atctgggtgt caccctgcct
    14941 gctaaggaca ggctttcaat cacaagccta gtgttgcagg acgttgggct acagctattt
    15001 tcggagacgg tagaaaagga gcttaatcta ggtcatcata gacatcaggc tactgatgat
    15061 ttggtgaata ggcttgggct ttctcagctt ctagacaagc accctgccag cctatcaggt
    15121 ggtgagcagc aaagggtgat gattgctgcc agcctcttgt ctgacaagga gattgtcatt
    15181 cttgatgagc caagcagtgg cttagatctg ctgcaaatgc aggctctggt tagtctttta
    15241 aaggagctaa agcagcaaaa aaaggtagtg attgtcatct ctcatgacga ggaattactg
    15301 gatcaagcct gtgatagtat ctatcagttg agcaggtaaa ggcctagcct tgctcaagcg
    15361 gtctggtgct gtattggtga tggctttatc gctccttgga gcagcaggtg ttcctgcttg
    15421 atctgataac cactagctgc gattgaccaa tcacaagccg ccaactcttg acaagctagc
    15481 agtagctatc acaattctag ggcatatctt ggcctagcaa gcagtgctgt attgtttata
    15541 tgccactctt catcttttag ttaggccgtc ctagcggccg cactaagggt gtgttaggat
    15601 cggctaatac ctcaaggcat ctacagtaag aaaacgagcc tcttcctttt tggagaggct
    15661 cttgattttt gatataataa tgaaaaagaa agcgaggttg agatgctgtt aaagagttcg
    15721 attgctaatt tgaagggtct tggtccaaag tcagctgaga aatttcaaaa attaggcatt
    15781 tatcagatca aggacttgct actctattat ccttttcgct atgaggattt taaaagcaag
    15841 tcagccttag agcttttaga tggtgaaaag gctgtcctta caggtagagt tgtgactcca
    15901 ccaagcgttc aatactatgg gttcaagcgt aatcgcctga gctttaaatt gaagcagggg
    15961 gagcttgtga ttagtgtcag ctttttcaat cagccttatc tgcttgagaa aatcgtcttg
    16021 gatcaggaag tggctatctt tggtaggtgg gatcaaaaaa aagcagcctt gacaggtatg
    16081 aaattgctca tgaccttaga agatgatttg cagccagttt atcatgtggc gcaggggatc
    16141 agtcaaccca ccctgattaa ggcgatcaga tcagcctttg atagcggtgc cttagctcag
    16201 ctggaagaaa atttaccaga gcccttgatt cagaaatacc gcctgctgcc gagacaagct
    16261 gctgtttatg ccatgcattt tcctaaacat atggaggatt ataagcaggc cctgcgccgt
    16321 ataaaatttg aagaattttt ctattttcag atgaatctgc aggttttaaa gcttgctaac
    16381 aaggcagagg gcaatgggtt agcgattcct tttcatcagc aggcagtggc aaaaaagatt
    16441 gctgctttgc ccttttcact gaccagagct caacaaagaa gcctggagga aatcttagca
    16501 gatatgacct caggggctca tatgaaccgt ctgttgcagg gggatgtcgg ctctggcaag
    16561 acagtgatcg caagccttgc catgtatgct gcccaaacag cgggatttca atcggcactc
    16621 atggtgccaa ctgagatttt agctgagcag cattacgata gtctttgtca gctctttcca
    16681 gatttgtcta ttgccctgtt gacatcgggt atgaaagcag ctgaaaaaag agcagcttta
    16741 tcggctattg ctgatgggtc tgtggatatg attgttggga cgcatgcctt gatccaagac
    16801 gcagtgacct atcataagct agggctggtg attactgatg aacagcaccg ttttggggtt
    16861 aatcagcgtc gcttgtttcg cgaaaaaggc aacaatccag atgttttgat gatgacagct
    16921 actcccatac ctagaaccct agccataact gcctatggtg agatggacgt ttccattatt
    16981 gatgaattac cggcagggcg aaagccaatc atcactcgct gggtcaagca tcggcaatta
    17041 gatagtgtgc tggcctgggt aaagaccgag cttgctaagg ggacacaggc ctatgttatc
    17101 tctcctttga tcgaagaatc tgaaactcta gatttgaaaa atgcggtagc tttagaggct
    17161 gagctgaagg attattttaa agcttcagct agtgttgcct tgatgcatgg caaaatgaag
    17221 gcagacgaca aggagatgat catgcagcgc tttaaggcta aggagattga tgtcttggtg
    17281 tcaacaaccg ttattgaggt tggtgtcaat gtgccaaatg ccaccatcat gctgatcatg
    17341 aatgctgacc gctttggcct tagccaattg catcagttgc gtggtcgtgt tgggcgaggc
    17401 agcaagcaat cctatgctat tttggtggca gatcctaaga cagactcagg caaggagcgt
    17461 atgaccatca tgacaacgac taatgatggc tttgtgctgg cagaggctga cctcaagctg
    17521 cgtggctcag gagagatttt tgggacccgt caatcaggtt tgccagagtt caaaacagct
    17581 gatattgtag aggattatca tatcctagag gaggcaagac gagtcgctgc tgagattgtt
    17641 gcagctaagg attggcagct ggaccctaga tgggctccga ttttggctaa tcttcgtgtc
    17701 gctgatcagt ttgattagat gtgaggctga cttgctggac agagctaata taaaaacacg
    17761 acaagaggtt cttagctgac cgagtcgtgc tttttgtgct atagatgagg agtagtagcc
    17821 tgtgattata ggagagctta gccttcgata taatccttca gctcttgacc tgtaagccca
    17881 gcgttgaggg cgatgagcaa ttttaacctg gccttagggg catttagctc cttgacaaac
    17941 ataacaccag ccctttttaa gctggcacca cctccgcgat aagcataaac tggctctgct
    18001 atgccattga agcagcgcga gaccaagaca acaggaatcc cagaggcgat taatttttcg
    18061 agctcagata ctgctagggg aggaacattt ccagcgccga gggcctcaat cactagtccc
    18121 tgaatcctat caggtgtcaa aaggcttaaa atacttccat ctcccatacc agcataggcc
    18181 ttgataatcg gaactgtgcc agaaatatga cgaagctcaa agcgaaccct tggctcagca
    18241 gtcttaaaga acagtaaatc gtccttcatg acgactccca aagggccatg agtcggtgtt
    18301 tgaaaggtcg aaacattggt ggtatgcgtt ttggtgacat acttagcggc atgaatttca
    18361 tcattcatca caaccagcac ccccttgccc ttggctttct catggctggc taccctaagc
    18421 gctgttaggt agttatagat accatcgctt ccaatctcgt tggccgagcg catagcacct
    18481 gtgataacaa taggcaactc tacaggcagc accattgtgt ctagaaaata agcagtctct
    18541 tctaaggtat ctgtaccatg tgtgatgacc actgcatcaa actgactagc cctttgttga
    18601 atgtaatgat acatcttgag catgtggtga ggggtgatgt gcgggcttgg cagatttaaa
    18661 aaatccacaa cagttaggtg gatatgctcc aggctaaggc caacctgatt cattggattg
    18721 ttttgatttg ggctcacctt gcctgcttca tcagcctgca ttgaaatggt gccgccggta
    18781 tgtaagacga ggatttcctt catttgatac tcatacttct ttcaatttat gatataattt
    18841 attttatcac aaatagaaga gagaacagaa ggatttgaca ataaaagcag tctttttcga
    18901 cattgatgga accctgctta atgatcgaaa aaatgttcaa aaaacgacgc aaagggctat
    18961 tcagcaatta aaaaaacaag gtattatggt tgggctggca actggtcgtg gacctgcttt
    19021 tgtgcagccc tttttagaaa attttggctt ggattttgca gtgacctaca atggtcaata
    19081 cattttgaca cgagacaagg tcttgtatca gaaccagctg ccaaagtcaa ccatttataa
    19141 aatcattcgc tatgctagcg ataaaaagcg cgagatctcc ttaggaacag cttcaggtct
    19201 tgctgggtct cggatcattg atatgggaac cagtccattt ggtcagatgg ttagcagtat
    19261 tgtgccaagg agtctggtca agacggttga gggcagcttt aaaaacctca tcagacgctt
    19321 taagccgcaa agcttcagca atcttgttac cattatgaga gagccgattt atcagattgt
    19381 cttggttgct tctgttgatg acacccaaaa aatcaaggaa agattcccgc atatcaaggt
    19441 aaccagaagc agcccttatt ccttagattt gatttctagc gggcagtcta aaatcaaggg
    19501 cattgaacgc ttgggcgaga tgtttggctt tgagctctca gaggtcatgg cctttggcga
    19561 ctctgataat gacttagaaa tgctctcagg cgttggtgtt ggtgttgcga tgggaaatgc
    19621 tgaggcagtg gttaaaagcg gtgctcactt tacaacagct tcaaataaca atgatggtat
    19681 ctctaaggcg ctggcgcatt atggcttgat tcattttgat gtggaaaaaa gctttaaaag
    19741 tcgcgatgat aatttcaaca aggtcaagga tttccaccgc ctgatggacg gagacacgat
    19801 tgaaacacca agaggctatt ccttaaagga ggctggctat cgagcagatt ttaaggtaga
    19861 ggaacttgtg gaatttcttt atgcagccag tcaaggggat aagcatcgct tttctcaggc
    19921 tttgatagac ctccatgctg cccttgataa ggcagctaag aaggtgcagg ccaaggagca
    19981 cccagagtca cccctggttg ggcaggttga tgctttgaca gatctgcttt attttaccta
    20041 tggctcattt gtattgatgg gagtggaccc tcagcccatt tttgagaccg tccatgaagc
    20101 caatatgggg aaaattttcc ctgatgggaa agcgcatttt gatcccataa cgcataaaat
    20161 tcaaaagcca gatgactggc aggagcgcta tgcaccagag tcagccatca aaaaagagtt
    20221 ggacaagcag cttcaaaaat cattgcagcg cttggaaaaa taaggctgtc tttattttag
    20281 aggcattaaa aagcaccttg agctgtgagt tgatctccta gctgttaagc atttggccta
    20341 acacttgggg tcacttcact tattagctca gggtgctttt tgatgtagac tagacaccct
    20401 caataaaagg gcccttaagt ctagctagtg gtaattagta tatgagagca gtagtccttt
    20461 agtagccttg tgagctgagg ctaagggcta ggtatggtta cttcacttag gctgcaaatg
    20521 cttctgacag ctgagagaat tcgtcttgct acagggtttt gtcatgctct cgaaccacta
    20581 ataggtcaac cttggcatga cgaaggatat attcagatga tgatccaatc agcaaccgct
    20641 caaaggtgtt aagcccagtt gccccaacca taatcaaatc aacctcttct ttgtcaggga
    20701 tatcgtgcgc taatagcgtt ttgggattgc caaattcaat cacctgcttg acctcagtca
    20761 gccctgcctc gcgtgcttgt ttttcaaaat cccccaagac ctctttagc
//
LOCUS       DARYVE010000036        20225 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYVE010000036 DARYVE010000000
VERSION     DARYVE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20225
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..159
                     /locus_tag="TVW25_001224"
     CDS             <1..159
                     /locus_tag="TVW25_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378853.1"
                     /translation="TYAVTDKRLFREHEFATKREAMQFIRELELANDKRATEYYLREW
                     RDANGRYV"
     gene            137..421
                     /locus_tag="TVW25_001225"
     CDS             137..421
                     /locus_tag="TVW25_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEL1378854.1"
                     /translation="MLMEDTFKKIKELEAACQDRTDNIKKPSHYQGRHGMEAIDVVKN
                     FAACPEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            446..658
                     /locus_tag="TVW25_001226"
     CDS             446..658
                     /locus_tag="TVW25_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378855.1"
                     /translation="MSFRLSWEINGQTVEVIGDYKTLKAAYDSIKVHVKDRDKFASPY
                     YRIWQKGAVHFVDYGKHNAFYKIEER"
     gene            663..863
                     /locus_tag="TVW25_001227"
     CDS             663..863
                     /locus_tag="TVW25_001227"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378856.1"
                     /translation="MMDTETLEAVYDALQLSLPKIIDMLKAASATRDDAYKEGVLDGA
                     DLIADTVIKAIGQMIDPEADHG"
     gene            856..1083
                     /locus_tag="TVW25_001228"
     CDS             856..1083
                     /locus_tag="TVW25_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378857.1"
                     /translation="MAKDDFLTGFVLTLLAACVFAAGFVIGSDCSSEHYEQQMTDLRM
                     QLVSTQQQLKQSREQNQRQTKRIAELTGNGG"
     gene            1094..1783
                     /locus_tag="TVW25_001229"
     CDS             1094..1783
                     /locus_tag="TVW25_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1378858.1"
                     /translation="MEIKCGNCLQLLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVAGLEKTQH
                     PTQKPVALMRDIITRHTTKGAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAK
                     KRIAELTGNGG"
     gene            1787..1969
                     /locus_tag="TVW25_001230"
     CDS             1787..1969
                     /locus_tag="TVW25_001230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378859.1"
                     /translation="MPELINTADLQTPIEALENNLDFFKSFYNDERFEDMENAKKLIE
                     RYEKAISILTEVQNES"
     gene            1959..2117
                     /locus_tag="TVW25_001231"
     CDS             1959..2117
                     /locus_tag="TVW25_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378860.1"
                     /translation="MKVKDLHKVLAKVDPELEVWINEKDGGVITKAKNVMTWNEHPNK
                     FFINAETQ"
     gene            2136..2717
                     /locus_tag="TVW25_001232"
     CDS             2136..2717
                     /locus_tag="TVW25_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1378861.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADWIEGHKADYITWEKADKADFVFRCINDLFNFGADMHTYDFDVSYEISKW
                     TQEHAYGFIVAVLFGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFSEIIDT
                     DFYSREDVRLTESEIRKDFDWAWERGFAKGVKE"
     gene            2714..2881
                     /locus_tag="TVW25_001233"
     CDS             2714..2881
                     /locus_tag="TVW25_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378862.1"
                     /translation="MNKSEIKNLVDRLSDLIDKCENDFEAMVFNPDGTFDLLLASHSA
                     LSKVLRGEVTE"
     gene            2878..3093
                     /locus_tag="TVW25_001234"
     CDS             2878..3093
                     /locus_tag="TVW25_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378863.1"
                     /translation="MKSYQKRFVEEYRQLTQRLSKLDKMLKKYAQGTLGFEPDCPIRL
                     LQEQRRVMSEYVDILEARAKFEGVDLE"
     gene            3167..3604
                     /locus_tag="TVW25_001235"
     CDS             3167..3604
                     /locus_tag="TVW25_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEL1378864.1"
                     /translation="MGNIPTPKANNFLEELKTIPDLIETLERDANLMSRSLIKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            complement(4109..4486)
                     /locus_tag="TVW25_001236"
     CDS             complement(4109..4486)
                     /locus_tag="TVW25_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1378865.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(4538..4723)
                     /locus_tag="TVW25_001237"
     CDS             complement(4538..4723)
                     /locus_tag="TVW25_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1378866.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            4839..5174
                     /locus_tag="TVW25_001238"
     CDS             4839..5174
                     /locus_tag="TVW25_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1378867.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            5337..5804
                     /locus_tag="TVW25_001239"
     CDS             5337..5804
                     /locus_tag="TVW25_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1378868.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            5819..7573
                     /locus_tag="TVW25_001240"
     CDS             5819..7573
                     /locus_tag="TVW25_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1378869.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKMVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            7570..7740
                     /locus_tag="TVW25_001241"
     CDS             7570..7740
                     /locus_tag="TVW25_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378870.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            7733..7999
                     /locus_tag="TVW25_001242"
     CDS             7733..7999
                     /locus_tag="TVW25_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378871.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEVLRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            8033..9253
                     /locus_tag="TVW25_001243"
     CDS             8033..9253
                     /locus_tag="TVW25_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1378872.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAYISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            9231..9896
                     /locus_tag="TVW25_001244"
     CDS             9231..9896
                     /locus_tag="TVW25_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1378873.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            9921..11108
                     /locus_tag="TVW25_001245"
     CDS             9921..11108
                     /locus_tag="TVW25_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1378874.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASVEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEGLRFEGKDEVLIPLNQTTPVDPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKESGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQTLDTLKDKNGRYLLQDSITSASGKVFLGKPVFVLSDDVIGED
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            11253..11555
                     /locus_tag="TVW25_001246"
     CDS             11253..11555
                     /locus_tag="TVW25_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1378875.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            11552..11899
                     /locus_tag="TVW25_001247"
     CDS             11552..11899
                     /locus_tag="TVW25_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1378876.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            11896..12273
                     /locus_tag="TVW25_001248"
     CDS             11896..12273
                     /locus_tag="TVW25_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1378877.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            12270..12740
                     /locus_tag="TVW25_001249"
     CDS             12270..12740
                     /locus_tag="TVW25_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378878.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLMNVRKYRYFDFYLKERGKNGKSKIWTT"
     gene            12712..13302
                     /locus_tag="TVW25_001250"
     CDS             12712..13302
                     /locus_tag="TVW25_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1378879.1"
                     /translation="MGKVKFGLRDFQYAVLGEDDNVATKKGGIKKLPGMKSAKLDITN
                     ELVTVSADDGPYVVLSGGITETKLEIEVLDLTTDARKDFFGIKVAAGVEKYNKNLTPN
                     NVACIFRTSDENGKAIWVGLLKGKFNLPGMETQTKEGSPNPKADTVTGNFVSRGTDGD
                     VLVIGREESHEFNYEAFAGFVFAGATDIKKGENFEM"
     gene            13354..13680
                     /locus_tag="TVW25_001251"
     CDS             13354..13680
                     /locus_tag="TVW25_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378880.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            13728..13877
                     /locus_tag="TVW25_001252"
     CDS             13728..13877
                     /locus_tag="TVW25_001252"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378881.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            13890..17813
                     /locus_tag="TVW25_001253"
     CDS             13890..17813
                     /locus_tag="TVW25_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1378882.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRALATETSVFTRFGKAAEKIGGKMKSLGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGIKTGDILSFSRTMIDLGESTNLSAEEAASSIAKIANITGLTSKEY
                     SRFGSSVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQTLSAIETAVINGGEDLTKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSIFGKGVGIIGSTIQGIGKMSQGLGALSGWLRTFKTGA
                     AAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGTAVSATEANALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMITAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHQGISQMASDMAQKLGISYDDAYRKLAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWENMTLEQKKLVVDGQQAMIEIFDSKELLAQWQALTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNASDKTAGETQSAQNKIDNVKQRVPADVKAS
                     DKTGPDVASADRAVNSPKQKSPAVIRAQDNASGVAEGVIGALARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAMVNDQKGPLYKELVTLPTGESFIPSGRNVILPLPRGSKVLK
                     ASRTKQLFPHYASGIGFDDTKIASLTTRLKSVQDKGQVIINTDPQLAELIKLLKDRDD
                     RNVTNNYTVNATNSSSSEDMFSQENMRRLLRELAYYTNGEGGRLA"
     gene            17813..18520
                     /locus_tag="TVW25_001254"
     CDS             17813..18520
                     /locus_tag="TVW25_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1378883.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERSIKSTNNDIDLIEVAGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVTVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKGTGN
                     GVLTINDFETGLENVQGELVIDMERHLVYKDVLSAWDNIVRTEHHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            18517..>20225
                     /locus_tag="TVW25_001255"
     CDS             18517..>20225
                     /locus_tag="TVW25_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1378884.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGAFAHLFKEEMKIKSDAGRRTKWQTFEINRVLRNSKEHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKTPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEHEKPEEQLVTLPEFIIDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQQQIDKRNQRELEEFRDTLKNLAL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDP"
BASE COUNT         6878 a         3336 c         4583 g         5428 t
ORIGIN      
        1 acttacgcgg ttactgataa aagattgttt agggagcatg agttcgcaac aaaaagagaa
       61 gcgatgcagt ttattagaga gctagagtta gctaatgata agcgagcgac agaatattat
      121 ttgagagagt ggagagatgc taatggaaga tacgtttaaa aaaattaagg agcttgaagc
      181 tgcttgtcag gataggacag ataacattaa aaagccatca cactatcaag ggcggcatgg
      241 catggaagca atcgacgtgg ttaaaaactt cgcagcttgc ccagagcacg aggagggttt
      301 ttattggggc aatgctgtta agtacctttt gcggtatcac gctaaaaatg gtgttgaaga
      361 ccttaaaaaa gcacgtcaga accttgattg gttaatcgag aagttggagg aagtggaatg
      421 ataccaaaat ttagagtgtg gaagaatgag ttttagatta tcttgggaaa ttaacggcca
      481 aaccgttgag gttataggtg actataaaac actaaaagca gcctatgact caattaaggt
      541 ccacgtcaaa gacagagata aatttgccag cccatattat cgcatatggc aaaaaggagc
      601 tgtacacttt gtggattatg gaaaacacaa tgctttttat aagattgagg agaggtgatt
      661 aaatgatgga tacagaaaca ctagaagcag tatatgatgc tttgcagcta tccttgccaa
      721 aaataatcga tatgcttaaa gcagcatccg cgaccagaga tgatgcttac aaagagggtg
      781 tactcgatgg cgcggatttg atagctgata ctgtaataaa agctatcgga caaatgatcg
      841 atccggaggc tgatcatggc taaagacgac tttttaacag gttttgtact tacactttta
      901 gctgcttgcg tttttgcagc aggatttgtg attggatctg actgtagtag cgagcactac
      961 gagcaacaaa tgacagactt gcgtatgcag cttgttagca cgcagcagca gcttaagcaa
     1021 tctcgtgagc aaaaccagag acagactaaa cggattgcgg aattgacagg aaatggggga
     1081 taaaaaacac tacatggaaa taaaatgtgg aaattgctta caattactaa cagagttaac
     1141 tgatggatca atcgatatgg tgataacaga cccaccatac aacatatcag taaaaaataa
     1201 ctttgctaca atggggcgga caggtataga ttttggtgat tgggataaag gcttcgactt
     1261 gttaagttgg attgatattg caagtcgaaa attaactaaa aatggtggaa tggtgatctt
     1321 caacgattgg aaaaatttag gagatattgc aagacattgc gaaaagacag ggttagtagt
     1381 aaaagatatt tttcgttggg tcaaagataa ccctatgccc agaaacagag atagaaggta
     1441 tattacagac agcgagtacg ggatatgggt cgtccgaaaa aattccaagt gggtatttaa
     1501 tcggaaatcg gaaaaatatg ataggccgga atacagatat ccaattgtag ccggactgga
     1561 aaaaacacag caccctactc aaaagccagt agccctgatg agggacatca ttacgcgaca
     1621 cacaacaaaa ggggctgttg ttttagaccc ttttatgggt agcgggtcaa ctggagtagc
     1681 ttgtctactg acggagagag actttattgg atatgagcta aataaagatt actttaatat
     1741 cgcaaaaaaa aggatagcag aattaactgg gaatggggga tgaaatatgc cagaattgat
     1801 taacacagcc gacttacaga caccgataga agcactagaa aataacctag atttttttaa
     1861 aagtttttac aacgacgaac gctttgaaga tatggaaaat gcaaaaaaat tgattgagag
     1921 atacgaaaaa gctatatcaa ttttaaccga ggtacaaaat gaaagttaaa gatttacata
     1981 aagtgttagc taaagttgac cctgaacttg aagtttggat aaatgaaaaa gatggagggg
     2041 ttataactaa agctaaaaac gtgatgactt ggaatgagca tccaaataag ttttttataa
     2101 atgcagaaac acaataatgt taaccgaggt acaaaatgaa catcgaagaa gcgataaagt
     2161 attttgaaga taagagaaaa gattatattg tatcaccaag tgtaatacat gtatcgactg
     2221 ttgaggtcat aaatatttta aaacaaatta agttagataa accaaagcca gaaattccgc
     2281 agtttgtcgc tgattggata gagggacaca aagcagatta tattacgtgg gaaaaagctg
     2341 ataaagcaga ttttgttttt aggtgtatta atgacctctt taatttcggt gcagatatgc
     2401 atacctatga ctttgatgtg tcttatgaga tatcaaaatg gacgcaagaa catgcctacg
     2461 gttttattgt tgctgttttg ttcggctaca caataaaaaa agaaaagctg tatattgttg
     2521 agatccctaa tcctaatagt ggcatagaac acaaacatat tgcactagca aggttagcga
     2581 atggaaaact tggattttca gagatcatag atactgattt ttattcaaga gaagatgtcc
     2641 gactcaccga gtcagaaatc cgcaaagatt ttgattgggc ttgggaacga ggttttgcga
     2701 aaggtgtgaa ggaatgaata aaagcgaaat caaaaattta gtagatagac taagtgattt
     2761 aattgataaa tgcgagaacg actttgaggc aatggtattt aacccagacg gaacgtttga
     2821 cttattactc gcaagccatt ctgcgttgtc aaaagtgtta agaggagagg taacagaatg
     2881 aaatcatatc aaaaaagatt tgttgaagag tacagacaac ttacacaacg tttgtcaaag
     2941 ctagataaaa tgcttaaaaa atatgctcaa ggcactcttg gttttgaacc agattgccct
     3001 atcaggctat tacaggagca gagacgtgtg atgtcggagt atgtcgacat attggaagca
     3061 agagcaaaat ttgaaggggt tgatttggag taataaaaaa agacgtccat gcgaacgcct
     3121 tcatgattaa atacccaaca atattatatc atgaatggag agttagatgg gcaacattcc
     3181 gacaccaaaa gctaataatt ttttggaaga attaaagact atccccgatc ttatagagac
     3241 ccttgaaaga gacgctaacc taatgagtcg gtcgctcatt aagtctcctc aatggtctga
     3301 tatgcgagtg tctggtgggg tcaaacaatc acaggaagac aaaaacataa aaatgttaca
     3361 catggtcagt tattacagtg atcagattga gcggctaaaa gaccgtcggc aagaaatggc
     3421 taatttgatt gtgcaaagca tgggaatttg tgagagccat gttttgctaa cgacttatct
     3481 tgactgtgat ggagactacg agagagccag agaacgctta aacataggta atcggaataa
     3541 atactttatg tttgttaggc gaggaaagga aagtctagaa ttgatactaa aaaatactaa
     3601 ttagatacaa attgatacta cataatacta ataaccatgt tattatagta ctgttgaaat
     3661 aacaagaaga gataaccatt ttaccaattg actatttatt tagtcgctga ctttaactac
     3721 gatcaaactt gttattttac taaagcttag tagctttgcg ttaaaggtgt taaattactc
     3781 ggttgaaccg gtcgggtaag tcgcaaatat gaagagagtt gttgagacgt aaggaaatgt
     3841 catgtgcacg catcttatga tattgcaggt tcgaaccctg ccgtctcaat cagcgtcggg
     3901 gagacgcgac cccatacccc tttaaaggca gacacgttct gatgtgtggg tttttatgat
     3961 taaccgcaag tccaaaacca agggtcgcaa ccttgcttgt ggttagtagg gacaacggtt
     4021 gtaagtcggt tcgattccga ctgttcctgt gctagtcatc acatcgtgat ggctttttat
     4081 tatgcaaaaa agaaccacta agtggctctt atgcttgtag ttttaattca agtgcctctg
     4141 tgaggacttg cgagaaattg agattttcat cttcggctgc tttgtttaac cactcaggga
     4201 tagtcacgtt cttacgtact tttttagagt ggtatttttt catgtaggca atcatatcga
     4261 tgccgattaa agcaatatca gaatcacgat actgttcttt taagtcggaa acggagctag
     4321 cctttggata gtcagtatag tcttcaagag caaagcctaa gacttcgaca gccatttcgt
     4381 aagcttcttg aaagtcttta ccttgagtaa ttgcttcagg tacatctgga aatgtaacca
     4441 tgatatagtc tgtgtcttgt gtgaatgtag ctggatagat taacataatg attctccttc
     4501 gatcactgtg agataagcaa accatctggc aagcggatta ttttaaaccc gcctgcttta
     4561 gaatggtatc ttcaaggcct tttccgaggt ctttgttgtg tagaggaaca atggtttgat
     4621 gtccgttatt atctcggaat tttttgtgac ttccgttttg actgacttca tagaacccat
     4681 tcttttttag cagttttatc atctgctttg gggtcattgg catattgctt acctcacttt
     4741 ctatacttat attatacacg caataaacat ggttgtcaat aggtatgcgc aaaaaatgcg
     4801 tatttttgtt ttctattttt tattatggag gttagggtat gaggccgcag aagttaacaa
     4861 ttgcgggtgg cagacgaacg actgttgact acgatgatag gtcagctgag tatcgtgact
     4921 ataatcgtaa cagatggaag tatgatagga agactaagca gttttataac tctaagattt
     4981 ggagagagac aagtaagcaa gtcttattgc aaagtgatta tatctgtgca atgtgtggtg
     5041 gagaagcaac gatgactgat cacattgtct cagttaagaa agattggaat aaaagattag
     5101 attggaataa cttgcaagca agttgtaaag cttgtaacga ttgtaaagca ataagagaga
     5161 gacggaaaac ctaaacgtac ataaaaagta acatacgcaa tcattgttcg ggaaataccc
     5221 cgcctatttt ttaacggggc tatattgttc ggaaacttaa gaacgcgccc ttttctgtgc
     5281 aaaaaaatcc ctttttgaaa tttttgaaac tgtaaagttt gtgtaaagga ggtcttatgg
     5341 gaagaaattt aaagctagtt gaaacgacaa aaaagcatct tacgaaagaa gaaaaaatag
     5401 tgcgagaaac cgcgcaaaat aaggcgtctg acggtcttaa aaagttgcaa aagacacctc
     5461 ctgaacactt taataatgta gctaagtacg agtataggag aatcatagaa gacctccaaa
     5521 acctacccct aagaaatctc gatagagggc tattagagtt atattgcaca tggtatgcta
     5581 tctacaaaga aacaagtaga aaactagatg aggttggtta ttttacgaat gatccagaca
     5641 aaggcattat tcctagtccg cttattttaa cattggaaaa agccactgcg aatattagaa
     5701 gtagtgccag tcaattagga ctaacggtag atagtcgcat gaagatgttt attccgaagg
     5761 aagaagaaaa acctaagagt atatttgata aatttggagg atagagagaa agggggtcat
     5821 gacaatagaa tacgattatt cagcaatcgg cgacatctat aaagatgacg ctttttatta
     5881 tgcaaaaatg gtcgttgatg aagagattaa agcaagtaag aaggtcttta aagcttgtct
     5941 aagacatttg aatgacctta aaaaaataga tgatgataat tttaaattta tctatttacc
     6001 aaaaaaagca attgacccca taatttttat tgagctattg ccagacgtta agacgggaaa
     6061 gccttatcct ttagcgatgt ttcagaagtt tattatcggg aatttatacg gatggcgaaa
     6121 gaaaacagat cattccttaa gacgctttag aaaagctatg atttcggttg ctcgtaaaaa
     6181 tggcaaaaca attctgatag ctggtatctt gctttatgaa tttttgtttg ggcataatcc
     6241 atctatgagt agacaattgt tttgtacagc taatgaccgt acacaggcta aaattgcttg
     6301 ggacatggca aagaagcaac tctcatcttt aagagcaaag gacgctgatg tcagaaaagc
     6361 cacgaaaatt gttcgtgatg agctgaaaaa cttacatgat gaatcttata ttagggctct
     6421 tagtcgagat actggggcag tcgatgggtt cgagccttac gttggcgttt tagatgagtt
     6481 tgcggcatca aagacaaacg aaatgttaga gcttttagaa tccggtcaag gtcagcttga
     6541 taatccgttt atcttgatta tctcaacagc tggtatggat ttgaatgtcc ccatgcacac
     6601 aattgagtat ccgtacatca ctaaaatttt agacgaagaa attgtagatg atggctattt
     6661 tggatatgtc gcagagcaag acaacgaagg tgaaattaaa gatgaatcaa attggataaa
     6721 atcaaatcca atcctcgagg ttgaagcttt gcacgataag ctaatggatt acctgagaac
     6781 gcgtcgtaga gtgtctcttg aaacaggtga aattaacaag gtacttatca aaaactttaa
     6841 catgtggcgg cagtcgagtg aggaatcata tattgataag caatcttggg aacttgctcg
     6901 tattgataaa cccgacacac ataaacgaag ggtctggcta ggtgtggacg tcggtcgtgt
     6961 tagtgactta tttgctatta caccagttat tatgatggac gatttttggt atattgacag
     7021 tttttctttt gttgcgacaa agtatgggtt aacggctaaa gaaaagcgtg atggtgtgtc
     7081 ttacagtaat ttagaacgtc aaggctattg cgagataaca acattagaaa gtggggttat
     7141 tgatgatgag agagttttag aaaaaataga ggagatggtc tattcgaatg actgggaagt
     7201 taacggaatc tgttttgacc cttaccaatt tggaacgctg cttacgatga ttgagaaaag
     7261 gcacccagaa tggcctctca tagaggtttc gcaaacgaca atggttttga acatgccaac
     7321 aaagcaattt cgtgatgatc tcaagaatgg caaaataaag cactctggca atccattgct
     7381 aacaatggct gttaataacg cttatatcaa gactgataac aatggcatga ggattgataa
     7441 gaataagaat agcaataaga tagaccctct ggacgctgct ttagacgggt atgcagtttg
     7501 ttacttagag ccatttgacg gctctggtta ctggacaagt gagaaaattt taggaggaga
     7561 gacactgttt tgattggttt tattttaaaa aacatacata cattaatctt gttagctgga
     7621 ctaggtttat tgatgtatgg gttgtttttg tttggtgata aagttggttt tatcgctagt
     7681 ggtcttattt taattttttt agctatctat gtagatagcg taggaggaaa acatgaataa
     7741 acgcattaag aaaaaacgta aattggaaac agcggttgtg atgcttgttg cagaaaatgc
     7801 tatgcaagct gaagtactca ggaatcaaaa cagacaaatt gcagagctga gatcgattat
     7861 acaacaaaac gcccaagcga caaatagaga gtttgcagca gttaaatcag cgacgctaga
     7921 caaccaagca gccattaaga aaattgggga tgaggtttat tatatcaagc aaaattataa
     7981 gcgcaagtgg cggaaataga tgttaatggt ttagaaagga ggtgagaaat cgatgagttt
     8041 ttttcaacct ttgggcagtt caaaggtgtc ctatgatgac tatgtatcat ctgttttagc
     8101 tggcgatgtc tcccaaaaat acttaggagt gtcggctttg aagaatagcg atattttaac
     8161 agcaacgtct attatagctg gggatattgc taggtttccg cttgttaaaa aggatgttaa
     8221 tggggacatt atccatgatg aggatattaa ttatctttta aatgttaaat ccacaaaaaa
     8281 tgcgagcgct aggacctgga agtttgctat ggcagtaaat gccattttga ctggtaattc
     8341 tttttcgcgt attttgagag atccaaagac taaccaagct ttgcaattcc aattttacag
     8401 gccgtcagaa acgactgttg aggagacaga taaccacgag atagtttata cgtttactga
     8461 tatgttgaca gcaaaacagg ttaaatgttt tgcccatgac gttatccact ggaagttttt
     8521 tagtcacgat acaattttgg gaaggtcccc gctactgtct ttaggtgatg agattgattt
     8581 gcaaaccggc ggcatcaata ccttaattaa attcttcaaa gatggttttt ctagtggcat
     8641 cttaaaaatg aaaggcgctt atataagcgg tgaagcacgt aagagagcca gagttgaatt
     8701 tgaaaaaatg cgcgagggtg caattggtgg tagtccttta gtattcgacg atacgcaaga
     8761 atacacgccg cttgaaatcg atactaacgt attgcaatta attacaagta acaatttttc
     8821 aacggcgcaa atcgcaaaag ctttgcgggt tcccagctac aagcttggtg ttaatagtcc
     8881 aaatcaatct gttgcccagt tgatggaaga ttatgtcacg aatgatttgc cattttattt
     8941 tgatgctatc acaagtgagt taggacttaa gacgctaagt gataaggata ggcgtttgta
     9001 tcgtatcgag tttgatacac gaagcgtcac aggtcgcaat gttgatgaga ttgtcaaatt
     9061 ggttaataac caaatcttga cgcctaacca aggcctcgta gagcttggta agcaaaaatc
     9121 aacagatcca aacatggata ggtaccagtc tagtctaaac tacgtctttt tagacaaaaa
     9181 agaagaatat caagacaagg ttggtatcaa agggaaagga ggtgaggtaa atgccaaaga
     9241 ggataaatct taaaggacca ctaattgcaa ataactctca agaagtttac gactattacg
     9301 gaatggaagc agcaagtgct aaaagtatca ttgagcaatt tcctgaagat aatagcgata
     9361 ttgttttgga agttaattca aacggtggac ttgtgacagt tgggagtgaa atctataccg
     9421 ctttacgaaa ttacaaagga aaagtaactg cagaaattac tggcatggct gcaagtgcag
     9481 catctgtggc tgttatgggt gcggataagg ttgtcatgag tcctacagct caaatgatgg
     9541 tgcataaagc actctttaaa tgggtgtctg gtaatagtga tgacctagac aaagcttcta
     9601 atgccttaaa atcaagtgat aaagctattg tgagtgccta tgtcgcaaaa acagggttat
     9661 cagaagatgc aatcatggat ttaatgcgaa atgaaacgtt tatgtccgct caagatgccg
     9721 tagaaaaagg ttttgcggac gaagttatgt cttttgaagc agttgctagc attgataatt
     9781 ccatgttgcc gcaagctgtt attgatgact attacagaag taggaacaaa cgaaaacaag
     9841 agattagcaa catgttacta gaaattgaaa aagaagaaat tttacgaggg ctataagctc
     9901 tttttttatt ggaggaattt atgttcgaag aaaaaatcaa agaaattaaa gcgaatatcg
     9961 ctaatttaaa ccaagctatt gctactaaaa caacagaagt aaaaaatgct ttggaatcag
    10021 atgaccttga aactgctcgc tcaattaaag cagaaattga agaagctaaa gcaaacctag
    10081 cagaagcaga aaatgacttg aaattgtatg aagctagcgt tgaaaaaggc ggtgcagaaa
    10141 atactggagg aaaagaagtg ccacaagaaa ctaaaacata tcgcgaaagc gttaacgaat
    10201 ttattcgttc aaaaggaaca gtaaccaacg aaggtttgcg ttttgaaggg aaagacgagg
    10261 ttcttatccc acttaaccaa acaacgcctg tagaccctaa aacggatggt gttaagaaaa
    10321 cggatgtaaa acctgtctct agtgaagaaa ttctttacac accagcgcgt gaagtcaaga
    10381 cagttgttga tttgaaacaa ttcactagca tccacccagc taaaaaagaa tcagggaaat
    10441 ggccagtatt gcaacgtgct acagaaaaaa tggttagcgt tgaagaattg gaaaaaaatc
    10501 caaaactagg caaaccacaa tttaaaaacg ttgaatggga agttaagact tatcgtggag
    10561 ctatcccact gtctcaagaa tctatcgatg atgcagatgt agatttggtt ggtattgttg
    10621 ctgaaacaat cggtcaaatg aaagttaata caactaatga tgcaattgct aaagtcctaa
    10681 aaacatttga ggctaaagct ggtgtcaaaa cattagatga catcaaaaaa atcctaaatg
    10741 tagatttaga tccagcttac aatgtatcat ttattgtatc tcaaagtttc tatcaaaccc
    10801 tagatacttt aaaagacaaa aatggtcgct acttgcttca agactcaatc acctctgcgt
    10861 ctggcaaagt gttccttgga aaaccagtat ttgtcctatc tgatgacgtg attggcgaag
    10921 actcagcttt tgtcggagat tttaagcgag gcgtgttatt cgctgatcgt aaagatttag
    10981 ggcttcgttg ggcagataac gaaatttacg gtcaatactt gcaagctgtc cttcgctttg
    11041 gtgtcgctaa ggtagatgac aaagctggat actatgtgac attcaaacca gaacaattgc
    11101 cctcataagg ccactgaaga agtggcgaaa ccaactagca aaagcactgt cgaggagatt
    11161 aagcgctatt taacaagcaa gggaattgac tttaatggga aaacattaaa atctgattta
    11221 ttaaaacttg caggcgttga agaggtatag ctatggctgt atcaaaagag ttattagaca
    11281 gtgtaaaact ctattgtaaa attgactttg attttgatga cgacatcatc aaagaaatga
    11341 ttgaatctgc tcaagaacaa atctgttttg caatagaaga cggttctact cctgaaaagt
    11401 tcaaaggtca cgctaaattt aatttagctg tcaaaaagca agtcaaggaa gagtatgacc
    11461 atcgcggttt gtctgcggat agttttcgct atccgttggc aaatggtgtt ttaaacatta
    11521 tccatcaatt gcgattgaga ggtgatgatt cgtgattaca cgcaagatga acgtcaggat
    11581 aacgattttt agccaatcag gcgggcaaaa tgaagatggt gaagtagtat ctgctgtcag
    11641 aaaggacttg tatacttgtt gggcagaagt gctaaaaacg cagttgagag attttaatta
    11701 tcaatcaaag tatcaaaacg ctagcaattt gccaacaaat aaggatacta aggttttttt
    11761 aattaggtat aaccctgaat tatctataga taacacgatg tttgttgagt ttggcaagcg
    11821 catttataag atagataaaa tcgaatctga cgaatctggc aaagatatta tcatgataag
    11881 tggagtaagc atgtcatgac aaaaggttta gatgaaatat tggctaatct gacaaagctt
    11941 gaagtaaaag caccaaaaac cgcaaaagca gcagtaactg aagttgccaa agaatttgaa
    12001 aaagcactta aagcaaatac ccctgtttat gagattgaaa cagatgagcg gctacaggaa
    12061 gataccgtta tcagtggttt taaaggagct aatgttggaa ttgtatccaa ggaaatcggc
    12121 tatggcaaag cgactggttg gcgtgcgcac tatcctaacg atgggaccat ttaccaacgc
    12181 ggacaagact ttaaggaaaa aactatcaat cagatgacac caaaagctaa acaaatctac
    12241 gcagcaaaag ttaaggaggg actagggctt tgattgctga aacagcagct tataaattat
    12301 taagtaacga taagacgcta aatgagttgt tggataggct cagaggcggt ccttttaaaa
    12361 atgggtttaa gcaaggcata tttacttatg atattccaga taacccagtt gacttgcgta
    12421 aggtagattt agcgcctttt atgcgaatca acacaacatt agacggtcct gctgattatg
    12481 cagatgatga gatactgtgt aacgagcaac ggatcaccat caatttttgg tgcaaaacag
    12541 cttctgaagc tgaccaaatt agcaaatgta tagatgatat tttaaaaaaa ggcggttttg
    12601 aaagatacac cgcaaacgaa aaaccaagat ataaagatag cgatattgac ttactcatga
    12661 acgtaaggaa ataccgctat tttgattttt atttaaaaga aagaggaaaa aatgggaaaa
    12721 gtaaaatttg gactacgtga ttttcagtac gccgtactag gcgaagatga taatgttgca
    12781 acgaaaaaag gtggtattaa aaaactacct ggaatgaaat ctgcaaaact cgatattacc
    12841 aatgaattgg ttaccgtttc ggcagatgat gggccttatg tagtgctttc gggaggaatc
    12901 accgaaacaa aactagaaat tgaagtactc gatcttacaa ccgatgcacg taaggacttt
    12961 ttcggcatta aagtggcggc aggtgttgaa aaatataaca aaaacttgac acctaataat
    13021 gtagcctgca tttttagaac aagtgatgag aacgggaagg ctatttgggt aggactgctt
    13081 aaaggtaaat ttaatttacc tggcatggaa actcaaacaa aagaaggatc tcctaacccc
    13141 aaagctgata ccgtaacagg taactttgtg tctcgtggca ccgatggaga cgtgcttgtt
    13201 attggaagag aagaaagtca tgaatttaat tatgaagctt ttgcaggatt tgtttttgct
    13261 ggtgcgacag atattaaaaa aggcgaaaac ttcgaaatgt aacaatcagg ttggatttta
    13321 aatccaacct tttatttttg ataaggagta gatatgtacg aaattacctt aaaaaaaggt
    13381 ggtgtagata aagttttttc aaaagacttt attaacgttg aggataattt gttggctgtt
    13441 gagcatcaag ttagacaaag cgctgtgttt agcgatgaga aaagacgctt agattctaaa
    13501 gcgcatagaa aacttaacga atcttacttg caaatgtttg ttgatatgta cgcaggtcaa
    13561 tttacagtcg atgatttaaa gcaatctgac atgagtgttt taaatacact taatgacctg
    13621 tacattgcag cactcggtgg agagcaagag gaagacgaaa gcgaaaaaaa ggaacaataa
    13681 ccccacaaga ggctaaagaa aacttactct tgtggataca gagccttttg aaaaacggtt
    13741 ataccatttt agatattaaa aaaatgcgct tatctgatat tgaattgatg gtacaagcgc
    13801 tagaaattga aactgtcgaa aaagaagaag tgattgaaac gaccttggat aaggcattcc
    13861 cattcctttt cggctagaaa ggaggctaaa tggggaatat aggtgattta gtagcaacgg
    13921 ctacactaga catatcacca tttatgtcaa acacaagaaa cctaaaaacc tacatgaaag
    13981 gcttagacaa ctcgttaaaa gctgttgaaa agagttttca agggcatggc gggcggatta
    14041 aaggtcttaa agcggtctat gctgaaacag gtagtgcatt aaaaggttac caagaattac
    14101 taaaaactca gtcacaaaaa tatagcgacc taaaaaaaga gataggcgat gttaataacg
    14161 ctactgctga gcaaaagcaa aaattgattg gcgctaaatc agccatgttg gagactgctg
    14221 cgaaagtcac agaattgcaa aacagattac gagcgttagc cactgaaact agcgttttta
    14281 caagatttgg taaagctgct gaaaaaatcg gcggcaagat gaaatcatta ggtgattctg
    14341 tagcaggagt tggtgctgca tttacgagag gagttaccgc tcctattgta gcgggcgctg
    14401 gttatgctat taaagcagct gttgactatg aaactgcgtt tgccggtgtt aaaaaaacag
    14461 ttgatgagac ggcgacagta tcctatgcta agttgtcgca aggcattagg caaatggcta
    14521 aagagttgcc agccagcgcg gtagaaatcg ctcacgttgc agaggcggca ggtcaattag
    14581 ggattaaaac aggtgatatc cttagttttt ctcgtacaat gattgattta ggagaatcca
    14641 ctaatctatc cgcagaagaa gctgcatcat ctattgcgaa aatcgcaaac attacaggac
    14701 taacgtcaaa ggaatattct agatttggta gctctgttgt tgccttaggt aataactttg
    14761 cgacaactga aagagatatt gttgcgatga caaaccgtat cgccgcatct ggtaaacttg
    14821 ccggcttaac taatcaagaa atgttagcgt tggcaactgc tatgtcaagc gtcggtatcg
    14881 aggcagaagc tggtggtact gctatgactc aaacattatc agcaattgaa actgctgtta
    14941 ttaatggtgg agaagattta acaaaatttg ctcaaattgc caatatgtca tccgctgatt
    15001 ttgcaagagc gtggaaagag aagccaattg ttgcattgca agagtttatt aaggggcttg
    15061 gtcaacttga taaaaaaggt gaaagtgcta caaaagtgct tgatgaactc ggtttaagtg
    15121 gtatccgcca gtctaacatg ttgaaatctt taggattagc atctgagact ttaggcaagg
    15181 ctcttggaat ctctaacaaa gcttggcaag aaaacactgc tttaactgac gaagctaata
    15241 agcgctatga gacaacagag tctaagctaa aaatgcttaa gaatgaagtt aatgatgtag
    15301 ctattgaatt tggtggccct ttggttgacg ctctaagaaa tgggctcgaa gcaggaaaac
    15361 caattattca aatggcagca gatttagcca agcaatttaa ctcgcttgac aaagagcaac
    15421 aacagcagat tatcaagtgg ggacttattg ctgccgccgc tggtccagct ttgtctatct
    15481 ttggtaaagg tgttggcatt attggcagta ctattcaagg cattgggaaa atgagtcaag
    15541 gtttaggagc gttgtcaggc tggttgcgca cttttaaaac tggagcggca gcagctagtg
    15601 caggagccga agctgccaca gcttctatgg gcggaatggc tggcgcggtt gccttattaa
    15661 gcaacccagt aacgtggggt gttttgctag gtggggcagc cattgtgggt ataggtttaa
    15721 ttgctgatag catgtataaa gcccaaaaac gcacagaaga gtggggaacc gctgtttccg
    15781 cgacagaagc aaatgcacta agtaacttta agaaaaaagt tgacgaaact aacacttcgt
    15841 tgcaaatgtt cgaggcaggc gcaggtagcg ttaagaaagt gactgaagct tttgatgatt
    15901 tggtcggaag tattgaaaag ttagctcaat caaaattaga taagaatata aacttagcta
    15961 aaaaattagg attatcagaa gaaaccataa atgctttgaa atccaaaact gaatcagtgg
    16021 ttaacaatgt taaaagcatg aatacccaga ttaaagcaat catggagaaa cacaacggtg
    16081 acatgagcca gttgtcaagc gctgaaaaag aacttgtttt gcgaaatcaa agagaaatga
    16141 ttaccgctca acttgattta atgaagttct ctgcatcaga aaagaaagct ttaacagcag
    16201 ctttgaataa cgaattagat gccctcaacg caagacagtt ggaaaaagta tccgaaaaca
    16261 ccgttaagat gcttgataaa gaaaattctg cttacaaaac aaaaaaagca gaattaaaag
    16321 aaattttaaa gcaatttgga agcgatacta gcaagctaag cgctgaagaa ttggctgcta
    16381 gacaggaagt tttgaataga cttactgagt taaatatgca gcacaaccta aaaaccaaag
    16441 ctttgaacga tcagtacctt gctatccaga gggagcgtgt ccaacggtta aaagaatctg
    16501 gcaagagtca agaagaaatc caccaaggga ttagccaaat ggcatcagac atggctcaga
    16561 agcttggtat tagctatgac gatgcttacc gtaaactagc ttattatact gagaaatctg
    16621 gtgaaacgtt gaaagttttg tcgcgtaata cggctaatgc tacggcggaa gtagcagcag
    16681 ctaacgctca gtgggatagc ttgtttacga gcgataatcc acaacaaagc ctaaacgaat
    16741 tgttatcgac cgcagaaggc tggaacagtt ttgaaatcat ggttaagaat gccgacgttg
    16801 aaccgacagg tagagccgca cttgctgaaa tgttggtagc tggtggccaa tgggaaaaca
    16861 tgacgttaga gcagaagaag ttggttgttg atggtcaaca agcgatgatt gaaatctttg
    16921 atagcaagga gttattagcg cagtggcaag cattgacgcc agaagaaaag gttttgctag
    16981 cgaaaaactt aacacaagaa ccaactatgt cggctcaaca agcccttgac agtgtcaagc
    17041 aaacagtacc tgctgatgtt aacgcaagtg ataaaacagc aggcgaaact caatcagcac
    17101 aaaacaagat tgacaatgtt aaacaacgag ttccagctga tgtgaaagca tcggataaga
    17161 ctggaccaga tgtagcaagt gctgacaggg ctgtcaatag tcctaaacaa aaaagtccag
    17221 ctgttatcag agcccaagat aatgctagcg gtgttgcaga aggtgttata ggtgcattgg
    17281 ctagaatccc aagaagtgtt acaacaacca ttacaacgtt tgtccgtaag atttttggac
    17341 atgaaaaagg gactgatttc caccccggcg ggttagctat ggtcaatgac caaaaagggc
    17401 cgctatacaa ggagttggtc actttaccaa cgggtgaatc atttattcca agcggacgaa
    17461 atgtcatcct ccctttgcca agggggtcta aagtcttaaa ggccagccgt acaaaacaat
    17521 tattcccgca ctatgccagc ggaataggtt ttgatgacac caaaatcgct agtctgacaa
    17581 ctcgtcttaa atctgtgcaa gataaggggc aagtgattat caataccgac cctcaacttg
    17641 cggagttaat taaactactt aaagacagag atgacagaaa tgtcacaaat aactataccg
    17701 taaacgctac taatagtagt agttcagagg atatgtttag ccaagaaaat atgagacggc
    17761 tactcagaga attagcttac tacacgaacg gagaaggagg gaggttagct taatgcgata
    17821 cattgaattt aatggcacta aaagcaatga tttaggttta ttgctagagc gcgaacgatc
    17881 aattaagtca acaaacaacg acattgattt aatcgaagta gcaggtcgtg acggtgtact
    17941 tattaaagac aacgaacgct taaaagcggt tgagcaagac tttccttttt cgctggttgg
    18001 tgacgtgact gtcaatcaac aaaaaataag cgaatggtta catgtcaagg gttggcacga
    18061 cttggcgttg tcttgggaca aggattatat ctatcgggct agtgttgtca atctttttga
    18121 aatagacgag atacttaagc aatttggtag attaaaagtt aatttcttaa tccaccctat
    18181 caaatattta aaaacaggta agcaagaggt gcctctcgta aatggaggta ctctacaaaa
    18241 tcctggcaat gtccaagcta aacctatctt aaaaatcaaa ggcacaggca atggtgtttt
    18301 aaccattaat gactttgaga caggacttga aaatgtacag ggcgagcttg ttatagatat
    18361 ggaaaggcat cttgtctata aggatgtttt atcggcttgg gataatatcg taaggacaga
    18421 acatcatcgc atgcctcttt ttgatattgg tcaaaacaaa atctcatgga ctggtaactt
    18481 tactatcacc gcagtgccaa actggggggt taaagtatga taccagtttt atacgaggcc
    18541 aaagaaacca aatttaggac ttttggcctt ggagaaattg cggacgctta cgaggttaaa
    18601 gctacacgtg agcgtaatgg caattactcg ttatatatca aatatccttt agatggtgcc
    18661 tttgctcatc tgttcaaaga agagatgaag attaagtccg atgctgggcg taggactaag
    18721 tggcagacgt ttgagattaa tcgggtgctg cggaatagta aagagcacat tgagattttt
    18781 gcacgccaca tatcgatgcg cacacaggac atcgctttaa aaccatttgt gagcgggtct
    18841 agcattgacg cagagtcggc actggaggtt tggcgggata atcttgtcgg tgatgatacc
    18901 tttgatgtta aaagcgacat tttaacacta ggcagcttta actgggaagt tgacaagata
    18961 ggcaatgcaa gaggcgctct cgggggtgtc gctggctcta tcttagatgt ttacggtggt
    19021 gagtacgagt ttgacaatcg cacaatcatc ttacataaac aaatggggcg taagacccct
    19081 acggttttgg agtatggccg caatatcgtt agcgtggaag aggagcgttt gcttgatggc
    19141 aattatacct caatctatcc ttacgtaaga tatacgccac aaccaaagcc gcaagaggaa
    19201 gcctctggta agccgcacat cggcgagcat gagaaacccg aagaacagct ggtcactttg
    19261 cctgaattta tcatagacgg tcagtatctt gacttatatg cccaacgcag aatacagatg
    19321 gttgatttat ctagtcattt taatgatgac aaaaaagagc caacagtcga agaaattaga
    19381 aagctggctc agaaatacct taaagataat aatgtaggcg cacctaaaat cagtatagag
    19441 gttgattata tcgacctgtc acagacgctt gactatcaag attttagagt tatggaggag
    19501 gtcgagcttt gcgatattgt accgctttac tatccaaagt ttggtatcac aaccgagacc
    19561 gaaaaagtcg ttgagattgt ctatgacgtc tatacagata gcaatcacac aataaagctt
    19621 ggcacgattg gccaatccat ctctaagagt ctgacaggtg gtgttacgca gcggattgag
    19681 acgctggaaa acaaccaaaa ggttattact aataatcaac agcaatttga gcttaattta
    19741 cccaaatacc tcaacgatct aaacggtacc aagatatggt acgaaaaacc agatgacaac
    19801 gttgagcaca agataggcga tttttggttt gagaaaaacg gtaaatatca gcgtacctgg
    19861 gtttgggacg ggaatcaatg ggtaaaaatc attgatactg aggatttaaa tcctaatcag
    19921 cgcgcttttg atgaggctat ggccgagatc gaaaagctta agcagcacca acaacaaatt
    19981 gacaaacgca atcagcggga gcttgaagag tttagagaca ccctcaaaaa cctagcgtta
    20041 ccagaggaag cgatcaaaaa aatcactgag gctatcaaag ttgatgacat cccgtcaatt
    20101 aaacagtcgt ttgatgactt aaaaaataaa gtcagcgaga caagcgaaac cgcacgatta
    20161 aacgctgaga ttatcgggac agatggtaag acccgctata acaaaaatct cttggttggc
    20221 gaccc
//
LOCUS       DARYVE010000037        20030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYVE010000037 DARYVE010000000
VERSION     DARYVE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(85..1350)
                     /locus_tag="TVW25_001256"
     CDS             complement(85..1350)
                     /locus_tag="TVW25_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1378885.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TVW25_001257"
     CDS             complement(1364..2221)
                     /locus_tag="TVW25_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378886.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TVW25_001258"
     CDS             2564..3856
                     /locus_tag="TVW25_001258"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1378887.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TVW25_001259"
     CDS             complement(3971..4744)
                     /locus_tag="TVW25_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1378888.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TVW25_001260"
     CDS             4869..5615
                     /locus_tag="TVW25_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1378889.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TVW25_001261"
     CDS             5630..6610
                     /locus_tag="TVW25_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1378890.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TVW25_001262"
     CDS             6849..7169
                     /locus_tag="TVW25_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1378891.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TVW25_001263"
     CDS             7194..7502
                     /locus_tag="TVW25_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1378892.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TVW25_001264"
     CDS             7513..8817
                     /locus_tag="TVW25_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1378893.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TVW25_001265"
     CDS             9098..11515
                     /locus_tag="TVW25_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1378894.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TVW25_001266"
     CDS             11530..12198
                     /locus_tag="TVW25_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1378895.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     VEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TVW25_001267"
     CDS             12323..13414
                     /locus_tag="TVW25_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1378896.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TVW25_001268"
     CDS             13921..14973
                     /locus_tag="TVW25_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1378897.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TVW25_001269"
     CDS             15002..15580
                     /locus_tag="TVW25_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1378898.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15778..16686
                     /locus_tag="TVW25_001270"
     CDS             15778..16686
                     /locus_tag="TVW25_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378899.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16922..18268)
                     /locus_tag="TVW25_001271"
     CDS             complement(16922..18268)
                     /locus_tag="TVW25_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1378900.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19308..19412)
                     /locus_tag="TVW25_001272"
     CDS             complement(19308..19412)
                     /locus_tag="TVW25_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1378901.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19792..>20030)
                     /locus_tag="TVW25_001273"
     CDS             complement(19792..>20030)
                     /locus_tag="TVW25_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA topology modulation protein FlaR"
                     /protein_id="HEL1378902.1"
                     /translation="YRAFKRYLKYRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNL
                     NNYKAVIKQYPHKTIVLKNQKQLNHYMNSIQHDS"
BASE COUNT         5652 a         4027 c         4505 g         5846 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggtaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aacaaaacct cggagacaaa ctagccagca gctatttctc atgagtaatc aacatgttaa
    15721 aatcttcttt ggagatatta gacaaccata attattatat catcaaagga gagaaagatg
    15781 acaaacaaaa caaagcgtac aggattggta cgcaagtacg gtgcctgctc agcagctatc
    15841 gccttagcag ctcttgcaag cctgggagca ggtaaagcag taaaggcaga ccagccagca
    15901 gcactaaaat atccagaacc tagagactat tttcttcata ctcgtgaagg tgatgttatt
    15961 tatgatgagg atataaaaag atattttgag gatttagaag cctatttaac agctagactt
    16021 ggtgggattg ataaaaaagt agaagaagct gcccaaaagc caggtattcc aggtcctact
    16081 ggccctcaag gtcctaaggg agacaaagga gatccaggtg cccctggtga gcgcggtcca
    16141 gctggaccaa agggcgatac gggcgaagcc ggaccaagag gtgagcaagg cccagccgga
    16201 caagctggag aacgtggacc aaaaggagat ccaggtgctc caggtcctaa aggtgaaaag
    16261 ggtgatactg gtgcagttgg tcctaaaggt gaaaaaggtg ataccggagc aaccggacca
    16321 aagggagaca agggcgaacg cggtgaaaaa ggcgagcaag gccaacgtgg cgaaaaaggc
    16381 gagcaaggcc aacgcggtga aaaaggcgag caaaaaccaa agggtgatca aggaaaagat
    16441 acaaaaccat cagctccaaa agcacctgaa aaggctcctg caccaaaagc tccaaaggct
    16501 tcagagcagt catctaatcc taaagcacca gctcctaagt cagcaccaag caaatcagcg
    16561 gcaccaacag gtcaaaaagc agccctacca gcaacagggg aaatcaacca cccattcttc
    16621 acccttgcag ctcttagtgt catcgctagc gtaggcgtcc taactctaaa aggaaaaaaa
    16681 gactaagcta gttattgtat ctttcctgta tgacactagc taacagctaa tcacaaacac
    16741 cagagagagg tcttttctga cctctctttt atatacactg agcacatgct tacctcaaaa
    16801 agacagtagt ctaagtttga ctactgtctc aaaaatcatt tttatctaaa gctttgatca
    16861 gcttgacaaa tggtagagaa ggacttgatt tctaaggcct ttgacctcag tttgactttt
    16921 gttaattttc cttacgtttt atagctgcta caccagctgt agccataact gcaagtgcag
    16981 ctgcggtgaa gaatgggttc acagcctcac ctgttgctgg caattgatta gtcgttttct
    17041 tcatctcagc tttagctgct gctgctttag aagctgtgtg agctggcgct gctactttac
    17101 ctgcttgatc agctttttca ggactgagtg gtttagcctc tggcttagtt tctggtttgg
    17161 tttctggaac tttaggtgcg tcttcttgtg gttttgaatg tggacttgat tttttaatat
    17221 ctttagcatc tagggcaacg cttctttcct cacctgttgt agcttgagaa agctttttgc
    17281 cgttgacaaa aatctcatag aaagtgccat ctagaagccc tttagaaaat acagctttgc
    17341 catcagctcc tgttgttact ttctctatca cacgacctac tctatgcttt agagtgactt
    17401 cttgtcctga taaaggttca gcatcttcat tacgaacgat aacaaccaaa ggtgttttac
    17461 tgtattctgg ctcaactgtt ccttttccgt caacagtaaa gctagctgaa tgcttgtcgc
    17521 catcaacacc tgttcgtaca gtatagcctt gaggaacgcc attcacaaaa attgataaac
    17581 ttcttcctaa aggaagcttg tcaaaaacag cttgtccttt ttcatctgtt gtcacagtcg
    17641 caagtgtttt tctgccactt gttatatcta ccacttggac gtcttttcca gataatactt
    17701 taccctcagg gtctataact gttgcggtaa aagcaaagct accttcaata acatcatcat
    17761 gatggtggtg tgcatgatca ctgtgatgac tactctgccc atcgtcaaaa ggcttagaaa
    17821 catcaatctt atccaataaa ataacatgat gatgatcgtc atgtggatac atcaaggcct
    17881 taccctctga agtatccaat aattgaatct tgtctaatgg caagcctgta tttttggcga
    17941 tataagcttt ttttacggca ataatatctt cagctgattg attagtgtct agcggtaatt
    18001 tatcagctgc tgctacagga tttgcggttt ctgatgcttt tgtaattggt ttatcagcca
    18061 tcacctcagt gctgtcagat aactgttgat tagctgtatc tgcagtatct ttatcctcac
    18121 ctaacctcgg ttggactaca gtgtgattat ccactgctgg tgattcatca gcaaatgcta
    18181 ctgacgagtt agttgacatc gctaaaccag cagccattaa agcagctggg ataagtaaag
    18241 agtatcgggt aacttgattc tttttcatta ataactcctt ataactatta ttcattttaa
    18301 ttaattaacc agttaactat atcaatctat caaaaaaaat atagtatgtc aacctcttaa
    18361 agtgatttaa tcagaacaaa cgtatgaaga aaatcatttg gtgaaaaaga agcttatttt
    18421 agctgaaata gatccattat aaaagaggtg tcgtgaagta actcaatatt cacctatttt
    18481 tgtcgcaagt attctaatag gaatagaaaa agggcagttg cttgcaacaa ctacccaatg
    18541 taaaaccgtt aaagacggtg acagaaaata actgttaact gaactacctc aaaagttaaa
    18601 ccaaagatct aaccgttgga tgttggtttg tagagcggtt atttttttat tgttatgttt
    18661 acaacgacta agctcatcag tgtaagggaa agggacttcc atattaagaa gtatatatac
    18721 atcctagatg agacgtgtaa tgaatgggtt gaacaaatag ttgcttaatt ttgggataag
    18781 ggttataata aaaatagaaa aagggcagtt gcttgcaaca actacccaat gcagaaccgt
    18841 ttgagacggt ggctggtttt atagttaaaa gataaccgtt aactcgccaa agttaaggac
    18901 ggttattttt tattgtcatc tttgaagatt tgatagcaca agctgataag cgcaatagta
    18961 aagctactaa agcctaaaag gatttatacc acttcaaaag ctgtcaatgc tttgactcat
    19021 cctttctgtt agattttgat gaactgccca taggcctcac ctacctttca gaaataagag
    19081 ccaccgtctt aacctttctg ctttatcatt atagcatatt gttattaagg ttgactattc
    19141 agactcgtct aaagaagtgt aatagttgct taattttggg ataagggtta taatgaaaat
    19201 agaaaaaggt agttgctcga cacaactacc catgcagaac cgtttaagac ggtggcatgt
    19261 tttatgttat taaaaaataa ccgttaactc gccaaagtta aagacggtta ttttttattg
    19321 tcatctttga agatttgata gcacaagctg ataagcgcaa tagtaaagct actaaagcct
    19381 aaaaggattt gtaccacttc aaaagctgtc aatgctttgg ctcctccttt ctgttagatt
    19441 gtgatgaact gcccataggc ctcacctacc tttcagaaat aagagccacc gtcttaactt
    19501 ttctgccttt ttattatagc ataccctatc tctgattgac tagcttaaga aggaggggat
    19561 gtgatttgga tacaaatttt tgttaacttt tttaaagtct ccaaatgatt taaaaaaatg
    19621 atattaatgc tctaagtaag aatattaata atatggtttt accacttatt gtatgaggta
    19681 tcatttctaa agagttattt ttcagacaga aggcttgtta aagcaaacag aagcaatact
    19741 aaaggcatta gatgataatc aaggcctttt tcatgtctta aaatgagtat actagctgtc
    19801 gtgttggata gaattcatat aatgatttaa ctgcttttga ttttttaaaa cgattgtttt
    19861 atgaggatat tgtttaataa ctgctttata gttatttaaa ttattttttg agcgtccgtc
    19921 taacagaatc catttcataa attcaacatc aaatttttca ttacagtttt cagccatatc
    19981 aggacgtgtt tgtcccctat attttaaata tcgcttaaaa gctcggtaaa
//
LOCUS       DARYVE010000038        20021 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYVE010000038 DARYVE010000000
VERSION     DARYVE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20021
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..1167
                     /locus_tag="TVW25_001274"
     CDS             <1..1167
                     /locus_tag="TVW25_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009552330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1378903.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKIKKQMSILTTQSIVITTALTRLGMRHLIIS"
     gene            1241..2743
                     /locus_tag="TVW25_001275"
     CDS             1241..2743
                     /locus_tag="TVW25_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1378904.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2724..4301
                     /locus_tag="TVW25_001276"
     CDS             2724..4301
                     /locus_tag="TVW25_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1378905.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4303..4509
                     /locus_tag="TVW25_001277"
     CDS             4303..4509
                     /locus_tag="TVW25_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378906.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4506..4925
                     /locus_tag="TVW25_001278"
     CDS             4506..4925
                     /locus_tag="TVW25_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1378907.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5122..5391
                     /locus_tag="TVW25_001279"
     CDS             5122..5391
                     /locus_tag="TVW25_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378908.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5427..5594
                     /locus_tag="TVW25_001280"
     CDS             5427..5594
                     /locus_tag="TVW25_001280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378909.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5776..6399
                     /locus_tag="TVW25_001281"
     CDS             5776..6399
                     /locus_tag="TVW25_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1378910.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6410..6790
                     /locus_tag="TVW25_001282"
     CDS             6410..6790
                     /locus_tag="TVW25_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1378911.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6793..7842
                     /locus_tag="TVW25_001283"
     CDS             6793..7842
                     /locus_tag="TVW25_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1378912.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7853..8119
                     /locus_tag="TVW25_001284"
     CDS             7853..8119
                     /locus_tag="TVW25_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378913.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8129..8482
                     /locus_tag="TVW25_001285"
     CDS             8129..8482
                     /locus_tag="TVW25_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1378914.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8479..8787
                     /locus_tag="TVW25_001286"
     CDS             8479..8787
                     /locus_tag="TVW25_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378915.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8768..9133
                     /locus_tag="TVW25_001287"
     CDS             8768..9133
                     /locus_tag="TVW25_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1378916.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9130..9519
                     /locus_tag="TVW25_001288"
     CDS             9130..9519
                     /locus_tag="TVW25_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1378917.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9529..10120
                     /locus_tag="TVW25_001289"
                     /pseudo
     CDS             9529..10120
                     /locus_tag="TVW25_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10182..10541
                     /locus_tag="TVW25_001290"
     CDS             10182..10541
                     /locus_tag="TVW25_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1378918.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10583..10912
                     /locus_tag="TVW25_001291"
     CDS             10583..10912
                     /locus_tag="TVW25_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378919.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10929..14183
                     /locus_tag="TVW25_001292"
     CDS             10929..14183
                     /locus_tag="TVW25_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1378920.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14215..14994
                     /locus_tag="TVW25_001293"
     CDS             14215..14994
                     /locus_tag="TVW25_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1378921.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14991..17048
                     /locus_tag="TVW25_001294"
     CDS             14991..17048
                     /locus_tag="TVW25_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1378922.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17048..17755
                     /locus_tag="TVW25_001295"
     CDS             17048..17755
                     /locus_tag="TVW25_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1378923.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17757..18371
                     /locus_tag="TVW25_001296"
     CDS             17757..18371
                     /locus_tag="TVW25_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378924.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18382..>20021
                     /locus_tag="TVW25_001297"
     CDS             18382..>20021
                     /locus_tag="TVW25_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1378925.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLLNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT         6744 a         3508 c         4504 g         5265 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaagataaaa
     1081 aaacaaatga gtatattaac gacccagtcg atagttataa ccactgcatt gacgcgatta
     1141 ggtatgcgac atctaatcat ttcttgacac tggacaaaaa acaatccaat agctttaata
     1201 ttttccgcaa agcaggtttc ggactctaga aaggagaaca atgttataca cagaaacgtt
     1261 taaagacagc acaggtaatg ctaaattact tgagtttaga ttccatcgtg agtctcgtat
     1321 gaggtatcag acaagcgatt taagcggcct ttttgacgaa gggtataaac tattgcttga
     1381 ctatatcaaa caccacgaaa gcaagcaaaa accacgcata caggagcttt tagactatgc
     1441 tgagggtaat aatcatacag tctgcgaatc aggccgcaga cgagaggctg atatggcaga
     1501 cagtcgtgct atacacaact acggtaagta tatctcgacc tttaagcagg gctatttagt
     1561 tggaaatcct atccgcgtgg aatatgagga caatgatgat gctaaaaaac aattgttcaa
     1621 ggagctggcg gataaaaata acttccacca acttaaccgt agacttgtca aggatttatc
     1681 caaggtaggc cgcgcctatg aacttatcta tcgcagcatg gacgataaga cagaggttgt
     1741 gcgattagat ccacgagaaa cctttattat ctatcaagct gatgttgggc aagctagcct
     1801 tgtgggtgtg aggtactata acaagagtca gctggataga acaaagaaaa cagttgaggt
     1861 ctacacagat aacgagatca tttactttga ttatgatggg caactgacag aggttgatag
     1921 gcggccacac atttttaaat ctgtacctat cacagagtat ctcaatacgg acgatggcct
     1981 tggtgattat gagacggagt tgtctttaat tgacttgtat gatgcagctc aatcagacac
     2041 agcaaactat atgcaagatt tgtcagatgc aatcttggct attattggtc gagtatcgtt
     2101 cccgagttat gtagacacca aggaaaaagc cattgaatat ctgcgtgcta tgcgcaaagc
     2161 taggttgcta aatttagagc caccagtgga taccgaaggt agagaaggtt ctgtagatgc
     2221 taagtatctc tataagcaat atgatgtcaa cggcacagaa gcttataaag atagggttgt
     2281 gcaagatatc cacagattta ccaacacacc agatatgtca gatagcaaat ttgcaggcac
     2341 gcaatctgga gaggcactca agtggaaagt ctttgggctt gaccaagagc gtgtagactt
     2401 gcaagcactg tttgagcaat ctctaaaacg tagatataag cttatcgcaa gagttagtga
     2461 gctgttaaaa gaaattgacg gatttgacat tagcaaactt aaaattactt ttacccctaa
     2521 cttaccaaaa tcgctacatg aaaaaattga agcttttaaa gcacttggag gggagttgtc
     2581 gcaaaaaaca acaatgtcta ttacagatat tgtggaaaat cctgataaag agattgcttc
     2641 catcaacgat gaggctaaaa atcgtagttt attggcgcaa aagatggagt cagaaggtag
     2701 aatgacggat agggagttag ctcgtgacta caatcatgaa taagagtaaa tattggcgtg
     2761 atcgtgttaa aaaagaaatg gacgcaaaag aggcagatga tatctccctt gaacagtcca
     2821 tgaaacaatt acacaattat cattttagaa atatcgaaaa agaaattgag tcattttatc
     2881 aacgttacgc tgataaagag aaaatagaca tcgcagaagc ccgtaagaga gtttctgagc
     2941 ttgacatttc tgcttaccag aagaaagcta aggaacttgt tgtaaaggct gagaagctac
     3001 gaaaagaggg taagacagta acgagagatg actttaccca ccaagaaaat gcagacatgg
     3061 ccatctacaa tttagcgatg aaaactaacg ctttagaatt gttgcgcttg aatatcgact
     3121 tggagatgca ggagctcgca aatggcgaac ataagctaac caagacattt cttgacgaag
     3181 gataccgcaa agaggttgag ttccaagcgg gattgttagg actgtcggtt gctagccaag
     3241 caagcgtgaa agggttggct gacgcagtta ttaacgctaa tttcaaaggc gcaaaatggt
     3301 cggatagcat ttgggacaga caagataaat tacgcagcat tatatcccag agcgtacaga
     3361 gtgctatctt aaaaggtaaa aatggtttaa ctattgcaag ggatattaga cgagagtttg
     3421 atgtgtcagt gtcttatgca aagcgaatag caatcactga gcatgcaagg gtgcagatgg
     3481 aagttagtag attatccatg gcggagaatg gctttgctat gtttgacatt atcccagagc
     3541 ctaaagcatg tgatgtttgt aaagacattg ctaaacaagg tccatatcac atggataagt
     3601 ggcgaacagg ggaaaacacg ccgcccatcc atccttattg caggtgtgca gttgttggag
     3661 tggaagaaga aaatagtagt aatcatgaat cacttgataa gcttattaaa acagagtata
     3721 atcaaagtat gaaagagtca tcgacttatg ctcgtaacgt tttgtcggca gtgtcattga
     3781 tagagcctcg aattacatcg caaattaagc atattgtcaa gcaatccaac ggtaatttac
     3841 aaggacttga ttttagatta aaaagtctag attctttggc cagaaagatc tctactgata
     3901 gcttgttgga cgatatttca ccggaagaag ccgcaaacaa cataaatgat gcattacgct
     3961 atacagctgt atttaaacca gataattttt ttgatgatta tcatagcatg aaaaatgcat
     4021 tggtcagaga tggttttaaa atcgaaaagg tgaaaaatac ttggctagat gatggtccat
     4081 ataacggtgt taatactgtt gtatcaaaag acaatgtcaa gtttgaaatt caatatcata
     4141 cccaagaaag ctttgattta aaaaacggga aactgcatga attatatgag gagagaagac
     4201 ttcctaatat aacacgaaaa cggaaggctg aactagacaa aatgatgttt gagcttagta
     4261 aatctttaac taaacctaac caaatagaaa gggtgaattg atatgattac aaaatatttt
     4321 tttataaaaa ccgaacaccc caaaattgtt agatattcta atgggttaac agaagtttat
     4381 aacagcgcaa aaggctggga agaacaagaa gcttggtacg atcgtctatt ctttagcgat
     4441 ttcagtgatt ttgaagaggt tacagaaaaa gaagctaaaa tgtttattgc gggattgaca
     4501 gcggcatgag tattgtggag ctagctttca gagtggctaa aaaagcccac cttggacagg
     4561 ttgataaggc cggtgtcgac tatattaagc accctataac tgttgcaagt tttgtaaaaa
     4621 ctgatgaaga aaaggcaacg gcttatcttc atgatgttat cgaagataca agtttgactt
     4681 tacttgactt ggaagagtat gattttcctc gaagtgttat agaggcagtt gatatactga
     4741 caaagaaaaa aggacaggat tatcaatcct atctaaacct tgttaaaaca aataaacttg
     4801 caagaactgt aaaattagct gatttaaaac acaattctga tttatctcgt ctctctgaag
     4861 taactaacaa agatttaaaa cgctataaaa aatatcaaga agctatcaaa tatttaaaca
     4921 attaaacaac aacagacggg caaccgtctt tttttgtacc ccaaaaacag gaggaaatga
     4981 tgttgaaaat agtgaaattt ttgaaatatg tttggattta taagtgtaaa cctgtcagtc
     5041 caagtcttta tgcatcgagt cggattgagt acttcaaacc tcttggttat tactgggaaa
     5101 aagcaacgat aggagaaagc aatgaataaa cgaatcaaaa agaaacgtaa actagaaaca
     5161 gtagtagtga tgctggttgc ggaaaatgcc ttgcaggctg aagcgctcat aaatcaaaac
     5221 aaagaaatca tggagctaaa atcaatcgtt gagcgaaacg ctctggcaac aaacgaagag
     5281 ttagcgactg ttaaagacac cgttttagac aaccaatcag ttatcaaggc aattggtgac
     5341 acggttgact acatcaagca aaattacaaa cgtaagtggg ggaagaaatg aagtatctca
     5401 agaaaaagta atagtaagga gttattttga aagtcaaaga gatagcacag gtgtttaatg
     5461 aatattcgga tttttttgtg gtacaaaacg gtaaatatct acctggtgac agaactagtt
     5521 tttttctaga ttgcgaattg gaaatcaaag aaatatctat cggaattcct gattgcttaa
     5581 ttattgaagt ataaaaaatt caaagtcgta gcaatacggc tttttattgt gccctgagca
     5641 tggcctaaaa aggctcaaat taatcactag cgtggcttgt ggataaatac acctaataga
     5701 gactagaaaa catgaggcgc ccgttttcgt ggctctgcag tgtgtttaaa agcaagacta
     5761 gcgtgggagg aaaaaatgaa taaaaaacta ttagaaaaac tttttaaatg tgctccagat
     5821 actggcacag gttcaggagg agcttctgat gcagatagcc aacaatccga aacagatgga
     5881 gaaccatcta gtgaagacag ctttaaagct ccacagtcgc aatcagagtt agatagctat
     5941 acgaataaag caatccaaaa ggcattggaa aatcaacgca aagatgaagc taaacgaata
     6001 gaagaagctg taaaagctgc tttagataaa gaaaaagact actccaagct atctgaagaa
     6061 gaacgtcagc agcgtgaatt tgaagatagt aagaaagcct ttgaagctga aaaagccaag
     6121 tttgaacacg ataaacttgt agtccaagtc gaaaaggatc ttatcgcaaa gggattgcct
     6181 tctgagtttg ctgaattgct tgctacaaaa gatgcagaaa atgcgctaga gcaagtcaaa
     6241 acattcgaag cagcatttaa aaaagcagta gctgatgaag ttaaaaagac cgtacgacaa
     6301 cttactccat caactggggc aggtgcaata tcaacacaaa caaactatgg ggcgaacttg
     6361 gcgagtaaga tcgcacaaca aagcaccaca ttattttagg aggaaaaaaa tgaataaacg
     6421 taaagtaaca acatcaaaag agattctcca caatctcgaa tacgaagcta ttacagtcac
     6481 tttagattca agcacagttg gcaaaaaagt tattccagcc ggtacagttt tggccggtgt
     6541 atcggattct gtttttaaag atcgcaaaca aaaagtaaaa actgtggcaa atcacgaggt
     6601 cagcggagag agcaatattt gtggaatttt gttaaccgat gttgatttga cagatggtga
     6661 taaagcaggt gcttgtgttt atcgcggtac tgtcaacgca gataaacttg ctgattcatc
     6721 aattgcagaa aattttacgg aattggcgac aaaactacca catgttgtct ttattaaggg
     6781 aggtaagtaa gcatggcatt gatccacgaa attatcacat cggaaaacat caaaggtttt
     6841 tataatgcta aaaatgagaa cattgataaa acgttagggg aaaaagcatt cccaccaaaa
     6901 cagcaattag ggcttaagct atcctttatc aagggtgcgg caggaaaacc tgtgacactt
     6961 aaagcggccg cttttgatac taaagtacct ctacgtgacc gcatggcagt tgagctgctt
     7021 gacgaagaaa tgccttactt taaagaggct atgcttgtta aagaggcaga ccgtcaagag
     7081 cttaacatta tatctcaaac aaaaaatagt gatcttattg acacagtttt agcggcaatt
     7141 tataacgata aggtaacgct tatcgcaggc gctaaagcac gtttagaagc aatgcgtatg
     7201 gaagtgctgt ctaaaggtaa aatccacgtc gcatcaaacg gtgtcatgaa agactttgat
     7261 tatggactag actcttcgca aacaactaag ccaagtgtta aatggtctga ggcagagacc
     7321 gcgacaccac ttaaagacat tgaaggtgca attgaaaaaa tggcagaacg tggctttgtg
     7381 ccagaagcaa ttatcatgaa ctctaagaca tttagtttga ttaaaaacgc taaatcaact
     7441 cttaaaatca tcaaaccaat ggcaccagat ggggcagctg ttaccaaagg tgatttgacg
     7501 acttatattg ctgatgaact aggactcaaa attttgttta aagatggtat gttcattggt
     7561 gacgatggca aatctcgtaa gtatttccca gatggctttg caactttggt acctaacggc
     7621 aaccttggct acactgtgtt tggcactact ccagagcaat cagatctcat gggtgggcac
     7681 gcaacagatg cagatgtgtc gttggttgag actggtattg caatcacaac tactaagaca
     7741 actgatccag taaatgttca aaccaaggta tctatgattg ctttgccgtc attcgaacga
     7801 ttggaagaag tgcaaattat cgactccatt gaccaagtat aaggaggggg ttatggctga
     7861 agttattaaa acttttaggg ataaagaaac cactaacact tactacgtag gagacgatta
     7921 caacggagac cgcattgatg agttgacagc taaaggatac ctatctggtg ataaggtttc
     7981 tgctgccgct atagagattg accttgacaa attaaaggtt gacgaaatta gagcaaaact
     8041 tgatgagtta ggcgtcgctc atgaccctaa actaaaaaag ccagaattat tagaactttt
     8101 gaaacagtca gctagctagg aggtgtttat gcaaaagata aacacagata gcattatagc
     8161 taacgtaaaa ctcgatttag gtattgatga caccttgcaa gacagtttgc tcaatatgtt
     8221 gctaaaacgt gttacagacc attttaaagc ggaatacggc gttgatgata tagacaacgc
     8281 cttttcgttt gttttggaag actgtctaat tgctaggttt aatcgcagag ggtcagagag
     8341 ggctaagtcg gaagaggtag agggtcataa aacaacctac tatgactttt taaatgagtt
     8401 tgagccttac gacaaaatga ttaagtccaa ccttaatttg attaaggata attctcgtaa
     8461 agggggattg tactttttat gagatatgca gataggatta cgtttgttaa ggcgacagat
     8521 gaacaatatg accctgattt aggtgagtac acatataccg aagtcatgat caagacattg
     8581 ccttgttttg tcatggactt aggtatggct aaatctgtgc agattttcgg agactatcaa
     8641 aaaacacgaa aagttgttta tttgcgccaa ccttataccg atttgttaga tcactgtctc
     8701 tacaaaggca aaaagtacaa ggtacaggtg gataagcaat ttaatactgt tttttatctg
     8761 gagggagatg attctatttg tagctgatat atctttaaaa gtagttggaa cgacagggct
     8821 aaagaataaa cttgaactta ttgccaaaaa agaggctgtc aagaagattg ttagagataa
     8881 tggaaaacaa ctacacagga aaatggtcca aaaggcagta tttaccaaag gtcattccac
     8941 tggtgctacc agaatatcca tcacaatgca gattggtgat gatggtttta gtgttacagt
     9001 aaaacctggc acgcattatg caggttattt agaaaaaggc actcgcttta tgagtaagca
     9061 accttttgtg ttgccagctc taaaagagca aaaagtaaaa ttcagaaaag atttggaggc
     9121 gcttgtcaaa tgattaaaac tagagatcaa tctatttttg acgagatgtt taagcgtatt
     9181 cagtctttag gttttaaagt ttatgattac aaaccgatga ctgaggttcc ttatccgttt
     9241 gtggaaatgg aatctactga tgcagaatat attccaaata aagatgacat taaaggctct
     9301 gttgacctcg tactgtctgt ttggggattg caaaaaaaac gaaagcaggt gtctgatatg
     9361 gcatctgcta ttttttcaca agctatgtca gtggctagtt ctgacagctt ttactggtcg
     9421 ttaaatattc gtcaatcatc tatccaagtg ttagatgaca caacaacagt gacacctctc
     9481 aagagagcga ttgtcacatt aagatttaat ttaagatagg aggtcgcaat gccaggacca
     9541 agtagattag gatccaaaga tgaagaccac tccacacaag aaaggaagga aaaaatggca
     9601 gcgcaagatc aagtacaatt agaagcaaaa caagggattc atgcaatcct attattccgt
     9661 ttgttaaaag aagcatcatc agaaaaagca gctaaactcg cttttcaaac ggaacacgaa
     9721 gttggtaaaa gtcgtgatgt cgacggtcaa aagactaaag atggtattat ccagtctgtc
     9781 ggagctttag aatacgactt taaagcaaca tctattttag ccaaaggtga caagttagca
     9841 gcaaaactag aagaagccat ggaaaaaggt gagcttgttg aaatttggga tattgattcc
     9901 gaaaaagcaa gtgaagaagc ttgatagcaa aggtaaatat ccagctacct attaccaagg
     9961 ttacatttca agtttcggcg ctaagaaaaa tgcagaagaa aatattgaaa ttgaaatgga
    10021 atttgccatt aatggcgttg gtcaaaaagg atttgcaaca ttgaccgaag aacaaaaagc
    10081 agctgtacag tacaaattta aagatacaac agcaggttaa tcaacaaggc cagttaatta
    10141 ctggtctttt atttttaaat ttttaaaggg ggaaaagaat aatgcaattg gaaattaaag
    10201 gtaaaactca taacatcaaa tttggcacac gatttgttgc tgaaatggat aagaatcaca
    10261 ttgcagaacg tgaagggatg aagtttggcg ctggtttgca atcaactgtt ccgtttttgt
    10321 ttgagcgtaa cgttgtgaca cttgctgaga ttatctatac agggacaatc acagagtcac
    10381 cacgaccaag cttaaatgat atttacgact acatcgatga ggctgaagat attgagaagc
    10441 ttttcgatga tgttttagat gagttgcgcc aatctaacgc gtcaaagttg tttatcacca
    10501 aactggacaa aaacatagcg gagatggcaa ccgaagctta aagagttcaa ccaaaaatta
    10561 ttcttcacaa gaaagctttg agatgattgt ccttaattgt gttagatatc ttggcatgac
    10621 tgacattaat gagattggtc ggttgacttt gtatgaatat gatttattga tgataggtaa
    10681 agcgctagcc tctgtagacg aggcatataa agctcacaag caagcttgga taaatcacca
    10741 ggtctcagct acgaggctgg tcggtggtgg taaaaacaaa agagaagttc ctgtttataa
    10801 aacattcaag gaattttttg attatgaaac agaaatcaag aagataacca atgaaattga
    10861 tgaaagctat gacaagaaag caatggattt acttttaaaa gccaaccttt aaatagaaag
    10921 gaagttaaat gggagaatct tattcagttg aagcggtgtt gacagcggtt gataaaacct
    10981 ttggtaagac tttaaaatca gcagttcaat caattgaagg actagaaaag cgttcaaaag
    11041 gcttctcggc ggtgtctcaa aaggctgggt ctatgtttaa aagcatgctt ggagctaact
    11101 tagcaggtca agctattaca gcgctaggac gtacagtttc atctggactt atttcgatga
    11161 tcggcgaaat gaatagctca gcaaaagcgt ggaaaacttt cgatgccaat ttagcagata
    11221 tcggatttgg caaacagcaa attcttgaag ctaaaacagc tatgcaagat tacgctacta
    11281 aaacaatcta ctcagcatca gatatggcca gcacatatgc acagttagct gctgttgggg
    11341 taaaggatac tgggaaactc gtaaaagctt ttggtggttt ggctgcatct gctgaaaatc
    11401 caaaacaagc tatgaagtca atcagtcagc agatgacaca agctgtggga agacctacag
    11461 tagcgtggca agatttcaga ataatgctcg agcaagctcc agctggtatg gctaaagtgg
    11521 ccaaagctat gggcaaaaac cttaatgaac ttgtagccga cattcaggct ggtagagtaa
    11581 aaactaaaga cttcctagaa gcagtaaaac aagctggtaa cgacaaaagc ttccagaaga
    11641 tggcgactga attcaaaact gtggaccaag ccattgatgg catgcgtgaa ggtttatcca
    11701 ataaattgca accagctttt gaaaaagtga accaatttgg aattagagcg attgaagcaa
    11761 tcgggaaaca actcgataaa atcaattttt ccaaatttgc tgcaggcctt ggtaaatttc
    11821 tcgagggcgt gaacattgat agtattattt caagaatatc aacatcaatt tcatctatcg
    11881 tttctaaaat aaaaggattc tgggacggat ttaatcaaac tggagcaatc agcgcttttt
    11941 ccggtgcttt acaaagtgtt tggggagcgt taaaaaatac tgctaaagcc atgagtggag
    12001 gaagctggaa gaccttcggg tcaatcattg gcgaaattgt taaacatgtt tctaatttcg
    12061 caagagtgat tggagatgtc gttggcaaga tggatccgag tagactaaaa agctggatag
    12121 ctactcttgc agctgttggt ggtggattga aaatctttga gaaattaaca ggtcaaagtg
    12181 ttattggatc ttttttagac aaaatcggct caaaattcaa aatatttgga aataaagcca
    12241 aagaagggac agaacaagcc tttaacggag tcaaaagaag tggtggcatt atcagtaaaa
    12301 tctttaacgg tttgggtaat atcgttaagt ctgccggtac agcgatagcg actgctgcaa
    12361 aaggtatcgc aactggtttt tctatcgcgt ttaaggggct tgggtctgcc atttctatgg
    12421 taccgccagc tacatggcta gctttaggag cagctatttt agcggtagga gcggcttttg
    12481 ccttggcagg aactcaagct gatggcatta gtcaaatttt taaaactgtt ggcgatgtcg
    12541 ttgtacaagt tttacaacag gtcactaaca gtctagctac tctaattcct attattgtaa
    12601 gcgctattgg ctccatatta ccaattgtag caggggctat ttctcaagtc gtcgcagcag
    12661 ttgctggcgg attatctcag attattacag ctgttgctaa tggtgtatca actattattg
    12721 gggctttcac aggtctactt ggtggtgttt ctagcgtcat tacctcaatt agtggtgtta
    12781 tccaatcgct ggcaggtgta attacctcag tatttaatgg catagcaacc attatttcgt
    12841 ctgtagggtc tgcaattaaa gatgtattaa cgggtctcgg cagtgctttt aaaggattcg
    12901 gcaacggtgt aaaatcagcc ttagaaggcg ttgggacagt aatcaaatca tttggtagtg
    12961 cagtcagaaa tgtccttgat ggtgttgcgc atattttcga ttctatgggt aatgcagctc
    13021 ttaatgctgg tcgtggcgtc aaagaaatgg ctaaaggcat caagatgctt gtagatttat
    13081 cgcttgctga tttagtcgca acgcttggag cagtcgcgac aggtcttggg aatatggctg
    13141 gctctgccgg tcagatgact acgttaagtt ctgccatgag cgaagtagcc aatggtatgg
    13201 cgcgtctagg aacaagcgct acgatagcaa ttactggatt aacagttttt gctactacta
    13261 taacaactat tcagaccgca attgcaactc taccaacaat cctaactgca gccgctagtg
    13321 gttttaggga gatcggggat tcggcaactg cagcagttgg tcgaatccag acttttgcag
    13381 ctggtacaac tgttgttgca tcagcgtttg ctagtatgca atctatgatt cgatctgcca
    13441 tggctgcaat agtaagcagc attataacat catttaacca agctgcctct caaatacaat
    13501 caattttatc tcgggtgcta tctcaagcta ggacatttgg atctcaacta gagcaacaaa
    13561 tgaggcaatc gggacagcgt tcaggacaaa atcttgctca ggggttgtct tctcaacaag
    13621 gtgctgttat taatgctgtt tctagcatgg ttaatgccgc ggtatcaaga gcaaatgcag
    13681 gtgctagtcc tatgcgtcaa gctggagcgt acatcggaca agggcttgcg caaggtatgt
    13741 attcagcgct aggagctgta acagcagcag caaacgctct tgtagcacaa gctgagaggg
    13801 cagcaagagc taaggcgatg attcactcgc catctaggtt atttgcaaaa cgagttggtc
    13861 aatatatccc tcaaggggta gccatgggga tatataaaaa cgctgatgtc gttgatgatt
    13921 ctgtaggtga gctatttgat agtatcaata gctttgattt taatattgcg gatagattga
    13981 caagtattgg cgctagattc caaggtgttg tcaaatcaga aagttcgcaa tcgttgtcgc
    14041 agcaacaaga gtttgtacat acagctcaac cagcgtatgt aaactttagt ttaggcggaa
    14101 acgaatacga agcatttgta agtgacatca ctaatcgaca agcaaaaatt gaaaaaatca
    14161 gactaaagag aagcagctgg tagttgtttc tcttagtttt atgaaaggag taaaatgtac
    14221 gaatttaacg atactatcag agggactccg aaagttactt tcaatttaaa aacaacaatt
    14281 ggcgaaaagg tattagaaga agagctcaat aatgatttag gtacctttag gacattgacc
    14341 gtttctggtc gtgatatggt ggacttagaa caccagacaa caagtgtttt agggcgagat
    14401 ggcgagtatt tccacaatgc cacagttgaa gtcagaaaac tagaaataaa agctaaaatt
    14461 actggaaaag ataaccggtc aatgcgtttg caatatgaaa aattaaacag attaattgtt
    14521 agtcataatc aagttttttt atcattttca gacgagccgg acagaaatta tctaggcatc
    14581 tttaaatcta aagatatacc agaagaagtt tctaacgaac aaatcattgg cttggttttc
    14641 atctgttatg atccatttaa aatgtcagat ataaaaacca aaaaaggtaa tactgttcaa
    14701 aatgatggcc tatttaatac aaaacctatc ataactctca acctctcatc atcaacaaaa
    14761 gaaattaggc tgctacacgt cgaaagtcaa aagtatatca gattaactgg tacttatact
    14821 actgacgaaa tcaagattga tatgacaaca ggtaagatta cccagaacgg ccgtaatatt
    14881 cttagtgatt tagacatggt taacagtcgc tattttgatc tattacctgg taaaaacact
    14941 ttgcagtgtg ataatgcaac gattacagct gatttcaggg aggtttatct atgatttatc
    15001 tctttgataa gctggagcaa ttagttgcta ctgttggtac tgatgacttg ctctcatggc
    15061 attttaaggt caaaaataat gattgggatc aagctagttt tgaggtacct gttgattatg
    15121 acattgagcc ttttgtttac tttggttttt ttaactatga tccaagccaa aaagaggacg
    15181 tttttaaact ctttaaagtc attgattaca acctagaaga tagcaagtat tataaaggct
    15241 tagataaggc tgagagtgac cttgatacta ttgctattat caaagacaag cgctttagac
    15301 aatcgtccgc agatgcttgt attgatggag ctttagaggg cactggttat caagttggta
    15361 aagttgaggg catttccgag atcaggaccc ttagctatta ttacatcagc ccacgagctg
    15421 ccatgatcaa gatgatagaa gcttttaact gcgaatttaa tgtcagatac acctttgtta
    15481 ataacaaaat tactagtcgc tatatcgacc ttaaaaagcg atttggcaag ccaacaggaa
    15541 agcagtttga gcatgggaat aacttattaa aagtcgtcta tgaggaatca acagatgaca
    15601 tcgtgacttg tctgattggc cgaggcaagg gcgaggaaat ccaatatgat gaaccagagg
    15661 caaaggaagt tgaaggacac ttaccagagg cagaaaagcg tcaaggttat ggccgaagaa
    15721 ttgaatttag cgatgttgtc tggtcagtcg aaaaaggcga ctcgatagac aaaccagctg
    15781 gtcaaaactt tgtggcgcta gatagtgcca gagaagaata cggattgtct caaaatggcg
    15841 agctaaaaca ccgatggggg gtctttgtca acgaggaaat tgaggacaag gcggaactct
    15901 taaaagccac atgggatcaa ttgcagcgct tatcaatacc catcagaatt tacaaggcgg
    15961 aaatcttaga tattggcccc gaaacgtgga aaggtgactc agtagccatt atctacgatg
    16021 aggtaaaaat agcttttgaa actcgtgttg atgagattga tattgataag ctaaacttta
    16081 acaggtcggt agtaactctc ggtgattata gcgttgtcca aaaccgcgaa gcaaggtcac
    16141 gcaaggaagc tgtccaaaac atgatcaatg atagcataga aaacatcacc ggccttggca
    16201 tgaacttaca agaatttttt caaggtattg aggaaaaaat tgccactggc aaaaaagaga
    16261 tggaagacaa ttggcgtaag gttaaccttg aatttgataa ctttaaaaaa ttaatcgaac
    16321 aagagggacg taactttaga gagcgtttag aagctgaaac aaaggaacta gatgaacgca
    16381 accaaaaaga actcgatgaa tttcgcgaaa ccctcaaaaa tctgtcgctg cccgaggaag
    16441 ccattaaaaa aataaccgag gccatcaaag ttgatgatat cccatcgcta aaacaaagtt
    16501 ttgacgagct caaaaacgaa gtcagcaaga acagcgaaaa atctcgctta aatgctgaaa
    16561 tcatcggcac gaacggtaag acccgctata acaaaaatct cttggttggt gaacctaatc
    16621 gcaccaagac ctatgatcag gattttgtgg agatagaagc aaatgacggt ggttttagac
    16681 gcggtgagac atacacgatt agctttagtc agacatgtga gttgctaaaa aaagtggcta
    16741 tcacgctgac gcagccgcat aacaaaggtc tcaagctggt gctgacacca accaaggcta
    16801 agatggaggc gcagactttt gacctaacca aggacataga ggttatcagc gtctatcctt
    16861 tgagctacag agctgtttta acaggtgact ggtataaatc taagcagatg gattttaatg
    16921 cggcagaagt gcaggattta gctctggaga tgtcttatag agacgttgtc gatagcaata
    16981 atgctagttt gattttggat tggtcctcaa atccagatgt tatttttgat ggaaatggag
    17041 gtagttaatg tcagagacta tatcagctat agttgtgcat aaaagcatga caaaaaacga
    17101 gtgggagtct agtgacatca ttttgccaca aggccagctt gtctatgagt ctgacacagg
    17161 ccatagtaaa tttggcgacg gtaaaaatag atatgcagat ttgatctatc aaggtggacc
    17221 acctggggca caaggtcccc aagggccagc tggcgaaacc ggtccacaag gcccaccagg
    17281 ccctactggt caacgtgggg aaacaggccc acagggtcca cctgggccac aagggccgcc
    17341 aggagcggac ggtaaaatga cgtttgagca gctcacacca gagcaaaaac agcagcttaa
    17401 aggtgctggc atacaaagca tatcattgga ttatgagggc tatttgacaa tacagctaga
    17461 taatggccaa tcgtttagat cagatattag cttaaaaggt cctcaaggag agccggggat
    17521 caatggtatg gacggtccaa gaggcgcaac gggtccccaa ggaccagctg gtgatccggc
    17581 gagcatacct gacgatgttg tcagacgtgg tgagttagct gcatatttgc ttaaatcaga
    17641 gtataaagcc aaaggcgcag gctctgggct aagctacaaa gttgtcactc aatcagagta
    17701 tgatgatctg tatgattaca gcgacaatga gttgatactc gtgacggagg gttgacatgg
    17761 catataagct ttacactaaa gctgatgttg gtgacaacat gttgcttgtt gttggccatt
    17821 tgcctgacaa tacaaagcga ttaaaaatcc agcgtgagac gttagatgta ttgagtatta
    17881 cccactatag ctcttatgat atggtacaac tcaagtcgac agtcaaaaga tcccacagca
    17941 aaaatacagt tgttactctt gtagctgcag ctgctagcaa gcccaaagct aagccaaagc
    18001 acgttttaaa ctttgctaag gctaataagg tctatctagg cagcactcgt gtaatagcgg
    18061 tttatctggg tgatcgactg ctctggtccg acaaagacag cagcgggaac aaaactgtct
    18121 ctgttgtggg gagtcttgat atcagacaat cacaaaaaat gctgtatttg tacttaatag
    18181 cgtcagacat tgcagatgtc aaaagcaagc gcattaaatc gatagcgata aatggcgtta
    18241 acctgtcaag cgctgcacaa atcaattttg aggatagcga ctattattgt ctagtgacaa
    18301 tcgagcgagt tgctaacatc aaagagatca aaaatatagc gcaaaaaaac aaaatcacgc
    18361 tagagtttta ggaggtaaca attgagcaga gacccaacaa ttgtaataga cgagacaaac
    18421 ctcgttattg gcacagatgg ccgcatgcat tacacgttta ctgctagtca agacaaccaa
    18481 aaggtcaggc taaaaagcaa ctgtttaggc acagcgcatt ttaaccagct gatgattgag
    18541 cgaggagacc aagcgacgga ctacgttgcg cccgttgttg ttgagggtac aggacaggca
    18601 acaggcgtct ttaaaagtct cgaggagatg cttagtggcc taaagtcaat taaactggag
    18661 ctaacagata ccaaaaactc aaatctgtgg tcaaaaatca aattgacgac aaatgggctt
    18721 ttgcgtgagt atcatcatga tcatatctcg accgagattg tcgagacagc agctggtatt
    18781 gccaaacgga ttgtcgatga tactggccaa aagctggcac taatcaatga gactatcaaa
    18841 ggtgttaagc gtgagtatca agacgcagat agacagctat ccgcgagcta tcaagcaagt
    18901 atcgatggcc tcaaagccca gctggccaac gacaaaattg gcctacaagc tgagattaag
    18961 ctgtccgccc aaggcttgtc gcaaaaatac gacgatgagc tgcgcaagct atctgccaag
    19021 attacaacga catctagtgg tactacggaa gcctacgaaa acaaactcga gggcttacgg
    19081 gctgagttta ctcgtagcaa ccaaggcatg cggacagagc ttgagtcgca aatcagcggc
    19141 ctaaaagcag tacagcaatc aactgcaaaa caaatctcac aagagatcaa ggatagggca
    19201 ggggctgtta gtcgtgtgca acaggatcta gatagttacc aaagacgctt gcaagacgca
    19261 gaggataatt acagtagctt aacccagacc gttaaaggcc tgcagtcaac tgttagcgat
    19321 cccaaaggca aaatccagtc acgatttaca cagctgcaag gtcaaattga gcatcgtgtg
    19381 actagagatg gggttatgag tatcatcaac gagtcaggcg atagcattaa gctagcgatc
    19441 caaaaggctg gtgggattga tgctaagatg agcgctaaag agattatctc agcgattaat
    19501 cttaatggtt atggcgtcag aatctccggt gagcgtattg cgctggacgg taatacgacc
    19561 gttaacgggg cttttggagc taaacttggt gagtttatca agctcaaagc cgatcaaatt
    19621 attggtggtt cgattgacgc tgctaagatt agagtgatca atcttaacgc tagcagcatt
    19681 gtcggcttag atgctaactt tatcagggct aaaatcgaac atacgattac aagtttgctt
    19741 gagggtaaag ttatcagagc tcgcaacgga gcgatgatga ttgacttgtt aaactctaaa
    19801 attgacttta acagcaacgc taccattaac tttaataaca aggacaatgc gcttgtacgt
    19861 aaagacggta cccacacagc ctttgtgcat tttagcaatg ccacgccaaa aaattataca
    19921 ggtagtgcgc tttacgcctc gatcgggata acctcgtcag gtgacgggat taacagcgcg
    19981 tcgagcggtc gtttttgcgg tgctaggttt tttaggtacg c
//
LOCUS       DARYVE010000039        19723 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYVE010000039 DARYVE010000000
VERSION     DARYVE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19723
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            421..1362
                     /locus_tag="TVW25_001298"
     CDS             421..1362
                     /locus_tag="TVW25_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1378926.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(1337..1540)
                     /locus_tag="TVW25_001299"
     CDS             complement(1337..1540)
                     /locus_tag="TVW25_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1378927.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(1921..3597)
                     /gene="dnaX"
                     /locus_tag="TVW25_001300"
     CDS             complement(1921..3597)
                     /gene="dnaX"
                     /locus_tag="TVW25_001300"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1378928.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(3597..4094)
                     /locus_tag="TVW25_001301"
     CDS             complement(3597..4094)
                     /locus_tag="TVW25_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1378929.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            4274..5044
                     /locus_tag="TVW25_001302"
     CDS             4274..5044
                     /locus_tag="TVW25_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1378930.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(5226..5498)
                     /locus_tag="TVW25_001303"
     CDS             complement(5226..5498)
                     /locus_tag="TVW25_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1378931.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(5521..6147)
                     /gene="udk"
                     /locus_tag="TVW25_001304"
     CDS             complement(5521..6147)
                     /gene="udk"
                     /locus_tag="TVW25_001304"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1378932.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            6243..7337
                     /locus_tag="TVW25_001305"
     CDS             6243..7337
                     /locus_tag="TVW25_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1378933.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(7602..8888)
                     /locus_tag="TVW25_001306"
     CDS             complement(7602..8888)
                     /locus_tag="TVW25_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1378934.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            9310..10473
                     /locus_tag="TVW25_001307"
     CDS             9310..10473
                     /locus_tag="TVW25_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1378935.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(10596..13214)
                     /gene="alaS"
                     /locus_tag="TVW25_001308"
     CDS             complement(10596..13214)
                     /gene="alaS"
                     /locus_tag="TVW25_001308"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1378936.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(13570..14571)
                     /gene="prsA"
                     /locus_tag="TVW25_001309"
     CDS             complement(13570..14571)
                     /gene="prsA"
                     /locus_tag="TVW25_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1378937.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(14634..15341)
                     /locus_tag="TVW25_001310"
     CDS             complement(14634..15341)
                     /locus_tag="TVW25_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1378938.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(15424..16062)
                     /locus_tag="TVW25_001311"
     CDS             complement(15424..16062)
                     /locus_tag="TVW25_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1378939.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(16112..16744)
                     /locus_tag="TVW25_001312"
     CDS             complement(16112..16744)
                     /locus_tag="TVW25_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1378940.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(16734..17291)
                     /locus_tag="TVW25_001313"
     CDS             complement(16734..17291)
                     /locus_tag="TVW25_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1378941.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(17490..19292)
                     /gene="pepF"
                     /locus_tag="TVW25_001314"
     CDS             complement(17490..19292)
                     /gene="pepF"
                     /locus_tag="TVW25_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1378942.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(19282..>19723)
                     /locus_tag="TVW25_001315"
     CDS             complement(19282..>19723)
                     /locus_tag="TVW25_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1378943.1"
                     /translation="IHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMDK
                     HLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHED
                     LSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         5785 a         4551 c         3750 g         5637 t
ORIGIN      
        1 caatcatagt agcttggcta ggttggcaga aaaatgagcc tctcctactc tcatcaaata
       61 aacagatagc cttaatgatg gctgagataa cagcatacaa agtcgttaaa gtcacttgta
      121 agaaaaagaa ggacatatct taccaccact atcttgctca tcaaagccct acggctttca
      181 gacaaaatct tcataacagc ggaaaggctg atgaagcagc tcagacaaaa agagcaagct
      241 ccttaacgtc aaggatcaga gatcagcaca aaaataacag caggctacat taagaactgc
      301 aattccttga aatagaattg cttttttaca aaaaaatcgt ctccctagac tgttccatca
      361 tctcacgtca tttgtattat ttgctcttga aatccagtca ttttatacta tactagaatt
      421 atgaagacat ctgaaaaaat ttaccaatta ctagcttgca gcgacgacta tgtcagtgga
      481 gaatacttgg cagagcagct caagctttct agaacctctg tctggaaatc catcaaaagc
      541 cttgaaagtc aaggccttca cattgaatcc ctcaagcata agggctatcg ccttattcaa
      601 ggagatatat tgctgccaga gctcatcagc caagagctca acatgccttt atcttatcat
      661 gagaaaagcc agtcaacaca gctagacgcc aagcaaggaa tcgagctaaa gcatactgct
      721 cctaggctct atctcgctcc aagtcagtat gcggccaagg ggcggcttaa tcgccaattc
      781 tttgcgtcac ctcatggcgg catttacatg tccttgcatc tcaagccaaa tgttccttac
      841 gcagacatgc ctccttacac catgatggtg gcctctagta ttgttaaggc tatttcaaga
      901 ttgaccggta ttgacaccca aatcaaatgg gtcaatgata tttaccttgg ccataaaaaa
      961 atcgccggta tcctgactga ggccattacc tctgtggaaa caggcgtcat tactgatgtg
     1021 attattggcg tagggcttaa cttttttgta accgaatttt ctgaaaacct caaagaacga
     1081 gcaggctctc tttttagcaa caagcctagt attactcgaa atgccctaat cattgacatt
     1141 tggaagctct ttaccacaat accaatcaag gaccatatta aggtctacaa agaaaaatca
     1201 cttgtccttc aaaaacaagt gagcttccaa gaaaatgatc gtcaaaaaac agcaactgcc
     1261 attgacctga ctgatgaagg acacctcatc gttcaattag acaatggtca gctacaggtc
     1321 ttaaggagcg gcgaaattag tctttcttcc tggggggatt aacagcatta atgatgtttt
     1381 tggtaaattg gtcaatagca taagcacgcc ttaaatctct aaagagcaaa agaccccaaa
     1441 acagagcaaa aatataatcg cctgaaaata ataaatcgct gaaaaaataa gcttcaaagg
     1501 cacaaatgaa tgccataaac ataaattgtc gaatagtcat actactatta taccaagaaa
     1561 actaaatttc cactaacgat tttcacgcag cttgaagaaa aaggcagtta gcctgcttca
     1621 agcttttttg ctgctctttg atagcctgta acagtcaaat aaaaaagagc tcactctaaa
     1681 aacgacgcca aaagccagct tgattgctag gcttgtagtc aattgtctca aatcagtgaa
     1741 tcactaagcc ttataagaac tcagtcattg ggtcacaatg acacctagct ctaagcagca
     1801 aaaaagagaa ccacaccggt cctctctagc ttggcttgtc agctatctat tagtgctgac
     1861 aatgagccct gtcatctcct tattctagac aattgataca ctaccaatca tcagctagcg
     1921 ctaatcctct atgagatgaa tcttatcagt taaaaagtca aacccctcag gcatgtcaaa
     1981 ggtcgcttgc tcagactctt tggctgtctc ttttttggtt ttgatggtca tggcaaactc
     2041 cgagcgaata tggtggaagt ctgcctttgg tactgccaag atatgaggag aaaaccctgc
     2101 tgccttactc atgatattcc caaacatatc attcaaatcc tgacgcttca tggcctgctc
     2161 agcgttaaag gcggcctcaa aggccaaaat agcattttca ctattggcta aaacaggctc
     2221 cgagcctagt aacaaagctc gatcctgtgc agaaatacta tctaaaatct cattccaagc
     2281 actttttagc gcttctaaat attgtcgtga ctgctggcta tcttgaacag tttcctccat
     2341 gattttcaat atcttttccc gatcaacctt gtaggtaaag gcctttggct tgatggaatg
     2401 agctggtgta gcctgcgcag ttagaccctt ttgagcctgt agctgtgata tcgtctccct
     2461 cagctgacta atctcatgct tcaagtcatc aacatcagct agcaggctag acggtatcgc
     2521 agtgtctgct gcttgtcctt gctctgccag ctgaatggtc atcatttcag cgtagattct
     2581 aggatgggtt ccttttttga tctcaggcaa atgcttggtt actgtagcaa tcattgtaaa
     2641 aagctgatca aaagacactg caaggttatc atcaaaaaga gctgactgcc tgtgatgatc
     2701 accacctgat ttcacaatga gcaggtctct aaaataggtt agcagatccg ttgcaaagcg
     2761 actcatgctc ttgccactat cataaattgt ttctagatta gctaaggcct gacttgtttt
     2821 ttgcctgatg agatgctgaa cgtagtcgtc taaggccgaa atagaaatag agcctgtgat
     2881 ttcttctgca atagcaagcg tcactcgatt gtcaaaggat aggctcaagg cctgatctaa
     2941 aatggatagg gcatcacgca tgccaccttc tgctcgtctt gcaattaaat gaagcgcctc
     3001 tatttcatag gctatgccct ccttgtccag tatcgccgcc aaatgctcac aaatagctgg
     3061 ctgcttaatg gctttaaatt caaatcgctg gactctagac aaaatagtag ctggaatctt
     3121 gtgtagttct gttgtggcta ggataaaaac cacattgtca ctcggctctt caagggtctt
     3181 taggagcgca ttgaaggccc ctgttgatag catatgcacc tcatcaataa tataaacctt
     3241 gtaggttgcc cggctaggag cataggttga cttatctcga atatcgcgaa tttcatcaac
     3301 accattatta gaggcagcat caatttcaat cacgtcctcc aggctgccag ttgtaatatc
     3361 tcggcaaata tcacaatgat tgcagggctc tcccttgacc tgattagggc agttcattgc
     3421 cttagcaaaa attttggctg cgctggtttt accagttcct cttggacctg aaaagaggta
     3481 agcatggctt atcttttctg actcaacagc ctgctttaag gtggtcgaaa taactgactg
     3541 cccaaccatt tcagcaaagg tctggctacg atacttccgg taaagggctt gatacattaa
     3601 ttctcaactc caaacatgtc aaaacgaaaa gatgtatttt ctagtaataa ggctacaaat
     3661 tgctctaaat agtcttgatc tatctgatca taatcagcaa caagactgga atccaaatcc
     3721 agaacaccaa caagcctgcc agccttaagc attggcacaa caatctcgct catggctgct
     3781 gaatcacagg aaatgtaatt agcatgcttt ttgacatcat caacgatgat ggtttgacca
     3841 gattgagctg attctccaca tactcccttg ccaagcttga tatgcacaca ggaaaccttt
     3901 ccctgaaagg gaccaaggat caattcttga ccatcaaaaa ggtaaaagcc tgcaaaaaca
     3961 gaatgaggca gggtcatttt taagagggca ctagcattag agagattggc caaggcattg
     4021 ctttcattag aaaataaggc tttagcttga gccaataata gctgataatg ttcaattttt
     4081 gtcgtcttat tcatggttct tattataaca tatctgctac taatcgttaa acgatttcca
     4141 caggaaaaga attttaatca gcctctctag aaaagaaaga gattttatga taaaatagtg
     4201 agtaatatta aaaaaatagg agagtcagat gccgttgttg agatataaaa agattatcgc
     4261 tacgacctta tttatgttat tagtgtttaa tggtattgag tatgaatgtc taaaccttgt
     4321 cagtcccaaa caaacctttt accaatccgc tgccttaatc ctctcaacca gcctactagg
     4381 gatctatctg attccctttt cactggctat tgcttatctc aagcgcatct accagataag
     4441 gatctcaacc ctgctattag ctgggctagg cggtctttat attagtggct ttttagcctc
     4501 ctttggcaat caggttttag agcaattttg gattagcctg ataaagccca atattgcctt
     4561 agaggagtgg acgggagctt tgacagggcc ttttgtggaa gagcctatta aggcctttgc
     4621 agctatgctt gtcatttatt tgctgccagc tattaatctt aagcaaaaat tagtcatcag
     4681 tctcatttct ggcatgggat tccagctgac tgaggacatt agctatattg caagtgcggc
     4741 tgatcggtcc ataaatgaca ttttgcctac aacgcttgcc aggattagca gctcaccaaa
     4801 ctctcattgg gtctatactg gtatttttac aatgggagca taccttttaa ttaaaaaatc
     4861 tcaattattc ccaaggtctc tgcagatttt ctgggtggta agtcctctag ccctacattt
     4921 tatatggaac tctcctatct cagatttagc tggtgtcgca gttattcatg gaacaataac
     4981 aacccttatc tttatcagtc tattcaaaaa aatccatgcc ctagacgaca gcatcgccta
     5041 ctagcgtcat aggacacgag caaccaagcc cagccgcatt tgggcatgtg atggctcata
     5101 tgcatatata gctactcacc tctcgcttaa gctataggca gctaaatacc tatcacaata
     5161 gcagaaaaaa tgactaccag tcttaaaagg gctagtagtc attttaagct aaaaacaagc
     5221 acttcttaca ggatatacca ctgatacaga taatagcaaa gcacaagggt catcagtatc
     5281 cccatatacc atgaaaggac aaaataccat ttcttcgttt tatggttaaa ataatgccca
     5341 gctagatagg ctccaatccc accacataag agtgacaacg ttaatagcat tttctcagaa
     5401 agtcgccatt gacctttttg ggctctgtgt ttatcactgc cataggccgc aaagaccaca
     5461 gcattccaac caaaaagcaa gattaggctt ggtagcattt gtctgtctcc aatcacagca
     5521 ctacagctca cctaagatgc tggcaatctt tgtgttgatg agatcaatag caaccacatt
     5581 gctaacccct tctggaatga caatatcagc atagcgctta cttggctcaa taaattgatg
     5641 atacatcggc ttgacaacgc ttgtgtactg ctcaataatg ctctcaaggc ttctgccacg
     5701 ctcaaccata tcacgctgaa tacgacggat aatccgaatg tcatcatctg tatcaacaaa
     5761 aagcttgata tccatcagct cacgcaaacg ctcgtcctct aataccagaa tcccctcaac
     5821 aataatgacg tcctgaggct cttggcgaaa agttctgttg ctgcgagtat gctccttata
     5881 atcatagatt ggaatatcaa caggccggcc agccaagagt tcctttagct gctgaatcat
     5941 gaaatccgta tcaaaggcta acgggtgatc ataattagtc ttaacccttt cctcaaagct
     6001 gatatgtgat tgatccttgt aatacgaatc atgctgaatc atcgcaattc tcgcatttgg
     6061 aaagctattt aaaatggcac gagacacgct agtcttacca ccaccagaac caccagtcac
     6121 accaataata atgggttttt taagcattgt aaactccaaa tctaaaagtc tttcggtcta
     6181 ttttaccaaa tttgccacta taatgctata atgaagagaa aacaaaataa aaggatagat
     6241 atatgataac caaccttccc actcaatggc aggaaaagct ggcaaagctt ggctttacta
     6301 atctcacccc aatccaagag caggtctttc agcccattgt tgatggcaaa agcctattag
     6361 gcattagccc caccggaaca ggcaaaactc tggcctattt atggccaagc cttctcaggc
     6421 taagccctaa aaaagcccag cagttgctga ttttagcacc taatactgag ctagctggac
     6481 agctttttga ggttaccaag gaatgggcag agcccttagg attaactgcg cagctcttta
     6541 tttccggaag cagccaaaaa cgccagatcg aacgcctcaa aaaaggccca gaaatcatta
     6601 tcggaacacc gggacgcatt tttgaattag taaggcttaa aaaaatcaaa atgatggcca
     6661 tcaataccat cattttagat gaatacgacg acctactgag tgactcccaa taccagtttg
     6721 tccaaaaact ctcccattac gcgcctcgtg accatcaaat gatctacatg agtgctacta
     6781 acaagataga gcaagccagt ctagcggatc ataccttggt cattgatctg tctaagcaag
     6841 cattgccttg cattgagcac tgctacatgc tggttgacaa aaggcatcgg accgatatcc
     6901 tacgtaagct agcaaatatt cctgactttc gtggtctggt cttttttaac agcctgtcag
     6961 acctaggtgc tactgaagaa cgcctgcaat atagtggagc ttctgttgct tctctagcca
     7021 gtgatgtgaa tgtcaagcag cgaaaggcca ttttagaagc ctttaaagag cagagcattt
     7081 cactgctgct tgcgacggac atagtcgctc gtgggattga tattgaccag ctagaatacg
     7141 tcattaacgc tgaggttccc cgtaataaag agcaatatac tcatagagct gggcgaaccg
     7201 gtcgtatggg acgatcaggg attgtcataa ctcttgtcag tcaccctgaa gacatcaagc
     7261 gccttaaaaa atttaccaag gtcactgaga tgtacttgaa gcatcagcaa ttataccaaa
     7321 aagaaataag aggctagctc aaaggatata aacctaaaaa gcttgcctcc aagtatgatg
     7381 taaagcaact aatcactatt tcttaccctt gctactaaaa aaacgaacgt aaagtccttc
     7441 tgacatgaag tcaaaacctt acgttcgttt tatattatac tgacaccact ggctttatta
     7501 gtatagtaga tactggccat gcttagccag actagatact ttcttgaagt gagcccgcca
     7561 tttagtcatg ctctagagcc ttacttgctt tttctgactg actagcggct accatatagc
     7621 tcagataagg tcacacattt gtatccttcc gcttttaggt attccataat acttggcaag
     7681 gcatctacac tggtctggtg aatatcgtgc attagaacaa cccctccagg ctgcaattgc
     7741 tgcttgacat ttgccatgat agcagcagta ttacgatttt cccaatctct ggtatcaact
     7801 gtccaaagca tttccttaag acccgatgcc cttctaacaa tatcattagt agctccataa
     7861 ggaggacgaa gatagactgg gcgttttcca caggcctttt cgatggcttg attggtcgta
     7921 ttgatctgtg tttggatctg atcaacggtt agggtcgtca aatcagggtg atcccaagaa
     7981 tgattctcaa catcatgacc agcagcacta accttcttaa ccaaagcctc atggccaaca
     8041 accttagacc ccatcataaa aaaggtcccc ttggcctgat atttggccaa aatatctaaa
     8101 acctgcggtg tggtcacagg gtctggacca tcatcaaagg tcagagcgac tagcttttgt
     8161 ccctcttttt ctgcctcttt tgccttcttt tcctccaaat actcttcata agcagtcttg
     8221 tctgaaccct ctagaaaatc tggattaatc acatcaaaca ggcttgcaag aggtattgac
     8281 atatgaccaa ataaaataag attacccgaa tcaatggcaa agccatcgct taatacctga
     8341 tttttttcta tcatcgtatc agtgctcagc ttgatctctt tgcctggata aagcttgcca
     8401 acctcttcct cgatgcgatc taagcgacca gcaactagct cctctagctt aaaggggcta
     8461 taatcctctt tcacatggta acgactaaca gccttttctg tagtcttttt tagaccaaat
     8521 aactgaggct tgtagaccgt cttgtagata accaattgat tgacctgctt gatatgtgaa
     8581 gcctcaagct taggctttac catgataaca gccttgtcag tctgcttgcc ttgatacaga
     8641 gacataggca gatttgacac ataaaaatcg tcagccttct caatcggaga caggtaatac
     8701 caatcctgct ttcctttctt gagatacttg acctttttga tctttggact atccttagaa
     8761 gcagtctgtt cgagcttaat gactctctga gtatcctgcc ctattttcca agatctaatg
     8821 aaggtaaacg caacaccgac caacaataaa cttaataaaa taatgagaat ataatttagc
     8881 tttttcaatc tcgtcctcca attaccctac aattttaaca caagatagtt ggaaaataaa
     8941 taaaaaaagt taggtttcct taactttttt cagtccaaaa taagggcaaa aaagtgtttt
     9001 atggtgcagg atttgcctga gttattttcc ctttatcaca gccatttgtc actggataag
     9061 gggctagata ttatacctaa agcttctctt tattgctatc attattctga cattcttagg
     9121 catgctattt cccttgatag gacttgattg ctgtttcttt agcttgtaag gatctcctaa
     9181 aaatgagagt atttttaagc ctataattta tatattcgaa aaattttgac aaaaatgagg
     9241 aaaaatattg atttatttag ctttagtgat aaaatgaggg tgaaaaatta aataaaggag
     9301 gacattgata tgtctcagaa gttgggaaaa caacttattc gctctgttgt tactgcctta
     9361 gccgccatag catttggaat atttcctgca agcgagacga ctaatcatat cacctatgca
     9421 gaggttaact ccttaacccc ttcggtagaa tggcctttag agcagtatcc taattactat
     9481 agcatagaag gaaagtctaa tatcaacacc aaggattttc ctaagctata caccactacc
     9541 gaaaaggttt acaaaaaaag tggtcgaagc actaagcgcg ttactgtttc tgatctgcaa
     9601 tacgctgcac ttgatggcta tggccgttca ggagctgcct atggtattat cacaaaggat
     9661 atgatcgcga tgtcagccgg ataccgcgaa aaatgggaaa gcaatcctga gccaagcggc
     9721 tggtatacat atcatttcaa agaaactggc aagctagcta ctgaggccga ctaccttcac
     9781 agcaaaagca agatcaaacg aacctcaaac aatagctatg aaagcatcgt ccttagcaac
     9841 ggtaagattc gcaacggcta tctttttgat cgtagtcatt taattgctga cagcttaggt
     9901 ggtcgtcctt ttagaaataa tctcatcaca ggtacacgta ctcaaaacgt tggcaacaac
     9961 gaccgcaagg ggggtatgca gtacattgaa aacaaagtcc taaactatat taaccacaac
    10021 cctcaggttc acgtttatta caaagccgta ccaatctact caggctctga attactccct
    10081 agggccgttg tggtttcagc gctctcctct gatggtaaaa ttgatgaaac cgtaagagtc
    10141 tttaacactg tcaatggctt taccatcaat taccaatata gcggcatcag ccatgataag
    10201 ggcatggagg cttctagtga gtcagaagct gaggatatta cagacgaaag cactccagta
    10261 gctgaaccag ctgatgagga ggctatggag acagaggctg ctgctaacga cacaatagtc
    10321 tatgttacaa gtaatggcca atcaaaggta tactggtata ataaggacca tctgccagag
    10381 aaggtcaatc tcaataaggt tgtagaaatg accgagcagg aagccctaaa tcgaggaaag
    10441 caccattcct ccttagaaaa aataaatcaa tagtctcata acgactaaca caagagctgg
    10501 ttgaagcaac cagctttttt tgtgtgatga aggattagac agctccttag ctaaaagata
    10561 aagaggctga taaagcactc aacctcttat cgcttttata aatgctctgg tactgcggct
    10621 aatagctctg atagcttgct tgcatcacta ccacctgcca tcgccatatc tggcttaccg
    10681 ccaccacgac ccgacacgat tggcgctaag gccttaatca gattgccagc gtgagctctt
    10741 ttatccttac ttgcaacaag aacattgacc ttctcaccaa tgcttgcagc cagcacaagg
    10801 acatctgaat aatctctttg cttccaatta tcagcaaagg tacgcaagac tcctgcatct
    10861 gatacggata cctcactagc aatgtaacgt agaccgtttg cttcctggac ctttttaaag
    10921 acatcaccag cctgagctgc tgctgctttt tcttttagct ctgccatttc tttttgcaaa
    10981 tcgcggagct gctcgctgag gctcacaacc ttacttggaa gctgttctat ttgcggcacc
    11041 ttaagcgtat gtgcaatttc ttttaggatg tcttcttgct tgcggaagct ttcaaaggcc
    11101 tgctgacctg tcactgctat gatacgacgt gttcctgagc cgatcccctc ttccttgata
    11161 atcttgaaaa gaccaatttc tgatgagttg gacaagtgag tccctccaca aagctcaaca
    11221 gaataatcgc caatctgaac aacacgaaca gttttgccat atttttcacc aaagagggcc
    11281 atagctccca tagcctttgc tgtttcaata tcagtttctg tggttgtaat agctaatgcc
    11341 ttccagattt gctcattgac ctcttcttca atacgacgca gctcctgggc tgtaacggct
    11401 tcaaagtgtg taaagtcaaa gcgtaaaaag gcttcttcat ttaaggaacc tgcctgagtg
    11461 gcatgttctc caataacctt gtgaagggca gcatgaagca gatgagtagc ggtatggttt
    11521 ttctcaacag catagcggcg cttgtgatca atagcaagag tataaacagt gtctaatgca
    11581 aggcttgcaa gaacctcaac agtgtgaaga ggctgaccat tcggtgcttt ttgcacatct
    11641 atcacacgag caacaaggtc acccttatca tttttgataa ccccatgatc ggcaacctga
    11701 ccacccattt cagcataaaa cggtgtctga tcaaacacaa gcaaggcctg tccttctgaa
    11761 accatctcac tacgctcatt atcaacgatg ataactgata agcgagaggc aacagtctct
    11821 gtttcgtaca aaaattctga tggctctgtg atgcctgcca gtgtctcatt ttgcatgccc
    11881 attgagccac ccttaacagc tgctgcacgg gcacgatcct gctgctcctt catagctgcc
    11941 ttgaagcctt catgatcaat cttatagcca gcatcttctg ctaattcttc ggtcaattca
    12001 actggaaagc cataggtatc atacagctta aagatatcct tgccatcaag cctgtcttgc
    12061 cccttttcct ttagctgcgc cagcaattga tccaaatgcc ctgatcctgc atcaatggta
    12121 cgtgcaaagg tttcctcctc acgcttgata attttttcaa taaagtcacg cttctcaaga
    12181 atctctggat aataggactc catgatatga cctacagtag ctactagctt ataaaggaag
    12241 gtctcatgaa taccgagcct acgaccatgc ataacagcac gacgaagcaa gcgacgaagc
    12301 acatagccac gaccttcatt accaggtagg gcaccatctc caatcgcaaa tgacaaggca
    12361 cgaatgtggt ctgcaatgac cttaaagctc atgttgtcac catcttggtc gtaagtatgg
    12421 ccagatagct tttccacttc cttgatgatc ggcataaata ggtcggtttc aaagtttgtt
    12481 tttgcgccct gcataacagc cacaagacgc tctaagccag cacccgtatc aatgtttttg
    12541 tttggaagct ccttgtactc tgagcgagga attgtagggt ctgcgttaaa ttgagacaaa
    12601 acaatattcc aaatttcaat ataacggtcg ttttcaatgt cctcttccag caatctaatc
    12661 ccaatatgat caggatcata agcctcacca cgatcaaaga aaatctctgt atcaggtcct
    12721 gacgggcctg caccaatctc ccaaaaattt tcctctaatg gaatcaaatg gcttggctca
    12781 acgcccagag caatccaacg attgtaagag tccttgtcat ctgggtagta ggtcatgtat
    12841 aatttttcct ttggaaaatc gaaccattcc ggacttgtta acaattcaaa gccccactca
    12901 atcgcttcgt cgcgaaaata atctccgata gaaaaattac caagcatttc aaacatagta
    12961 tggtgacgag ctgtcttacc aacattttca atatcgttag tgcggattga cttttgagcg
    13021 ttggtaatac gaggattttc aggaatgact gacccatcaa aatatttttt gagggtggcc
    13081 acaccagagt taatccaaag cagggttggg tcattgactg gcacaagatt ggccgaaggc
    13141 tcaatagagt gaccttttga tttccaaaaa tcaagccaca tttggcggat ttgggctgat
    13201 gttaactgtt tcatgattaa gataccaaga gcgattagag agactgggta tgattgtcct
    13261 tagcataagt agcctgggga gacgatctct actcgcattc agttcctttc gttgattttt
    13321 tatgggatta ggctaaaagc catcaaaaca aaacaagccc atatcacaga gggcgaaaac
    13381 cgcggtacca cctctattca atgagcttgt cattcttaat tacttatatc agataaaatc
    13441 acattaagca gcatgcctat cagattatcc gtaactcaca gcaaccgtca cttctctggg
    13501 tcaaatcctt gataaacaat tcttaactaa accagtataa agcttttttg agcattcgtc
    13561 aatgaaaatc tatttttctg acttagattt agaagattga ctatccttgc ttgagtctga
    13621 agatgatttc tgatctgact tgcttgtgtt cgccttgctt gcttttttat cagtattggc
    13681 atactgtgcc aagatattag caaatgcttg gtctttgatc ttaacatttg ccttgtctaa
    13741 ggcctttgca atgaccttat tttggaaatc aatgttttgt gtcttttcag ccaagacaat
    13801 ttcttttaga cgtttcttat atttcttcca atcagaagcc ttttcggctt ttttggttac
    13861 cttaacaata tagaacttgt tttgataagt agccggatct aagacagaaa ccacctctga
    13921 aatatcaccc tcttttaatc ctgaggcggc cttgatcaca tctgctggta acttagtgtc
    13981 tcctgagtca aacttatagt ctaccttctt gtctgctgct gttgtctttt ccttagcaat
    14041 agcagcaaag tcagcaccct cagccttaac ctcacctaaa acagcctttg ctgtttcttc
    14101 attgtctaga gtagtgacct gagtagtcat ttctggtgtg tatgactcat aggctttttt
    14161 gtaatcagca tctgtcagct cttttttagc tgcttcttta acagcatatt caaccagcat
    14221 ggctgagcga atttgacgct tgtaggtatc tgttgtcaag ccagactgcg caagggctgc
    14281 agagaatgac gcaccgtatt gctcagctga tttattgtaa gcttcttccg ttcttttctt
    14341 agaaaccttt ttaccgtatt ggtcctcaaa aacacgacta accacaaggt ttagcattgc
    14401 tctttgagaa atctctgtat tttttgtttc attgtaaaaa tcactaacac tgatagtgtc
    14461 gcccttcatc gtaatgacac ttgtattgtc atttgtagac tgacaggctg ctagggtcat
    14521 tgctgatgct agggttacga taccagcaag taatttagtt gattttttca tgtgattttg
    14581 tgctcctttt tgtcattaac cagtatatta tatcacaatt tcttaaacgt aacttaatct
    14641 aacaaacgaa tatctgcttg atttttacga atcatcagca agccatcact aagcggcagc
    14701 aggctggctg tcaatccagg attatcaaga gttgctgcaa ataagtcctg aaggccacga
    14761 taaatcgtgc gctgtcctct ccgaacctcc ttgatcggct tagcaatgtc acccccctga
    14821 aacacatcat ctaaaacaac cattccacct atttttaagt gctttaacac ctctggaaga
    14881 aactgaatgt attttgattt tgcagagtcc ataaaaacaa agtcaaactc gccagtaagt
    14941 cctgctaaaa gatcagccgc atctccttca agaagggtaa tttgcttgcg gctatcgtat
    15001 tttgcaaaat tttccttggc aaagccaatc atctcagcat tgcgatcaat cgttataatc
    15061 tctgcctcag gagcattttc tgccattagc aaggcagaaa agccaatagc tgtgccaatt
    15121 tctaaaatcc ttttgggctg caagctttgc aataaaagcc tgaaataagc aacaacctca
    15181 tgctggataa tgggaatatt ttcttgtctg gcaaaggcct caagctctgc taaaaagcct
    15241 tcgttttgct ttagctgcgt tcgcatgtag tgaacaatgt cttctttgac aatagagcgg
    15301 cgcatattat gatttgcatt tttactatat gatttaacca tgctatccat tatataaaaa
    15361 aactctaggt aatgctaggg ctttcactag cctattcacc tttgacgatc tgagtagtat
    15421 ctatcaaagg agctcacaga cagccttaag ctgcttgaca atgctatcac aagcagacaa
    15481 gtcctgtaag ggataatcag gattggcaaa gccgatacag gtcatctgag cagccttagc
    15541 agcctgacta ccatgcttac tatcctcaat gacaaggcag gtcttgggat caacgcttaa
    15601 ccattcagca gccttaagaa aaatatctgg cgctggcttt gagcgagcaa cctcttcacc
    15661 actaactaac acctcaaagc agtccaaaag acctagtgca gtgagatttc taataatatc
    15721 tgccttaggc gatgaggaag ctactgccaa gcgatagccc ttcgcatgca ggtgcttgat
    15781 taattgagca gcacctgcta tggccttgac accgtcacgc tcaagcattg cttgacgacg
    15841 atgattcatc tcagcgatga gggcttcaac agaatcctct agctgacact cctttttcat
    15901 agttgtccac atatcgtcaa aggtggttcc cataaactgg tactgatacg cttcattggt
    15961 atctatgcct cggtccaata gcatttgtgt cttggttgac aaaaagatat attctgagtc
    16021 aacaatcaca ccgtccatat caaaaataag gcttgttttc atcatctacc tcctcttatg
    16081 ctatatctca gtcaggtcaa gagcaagact attaattact agagctattt ttaccagaaa
    16141 aaagctcaac aatatctgac agctgactaa tatgatgatt atcatcacta tctggcagca
    16201 ataggttgat agagctaatc ccagctgccc ttgctgcagc aaggtctaag ggcctatcac
    16261 caatatagta ggtctgcgac ttatccatct gataatgatg aatgagaaaa agaagcgctt
    16321 cagggtccgg cttacgctta aagccacaat ctgctgtaat cacctctgta aagtaatcag
    16381 caatccccag acgctgcaaa acagcctgag tggttcgtcc tttatgagtc acaataaaag
    16441 gcttaacccc ctgctgagag gttaaggcta atgtttcctt ggctgtaggc attagtgcta
    16501 ttaggtgatc acgcgcttcc tgctctcggg taaagaaggc cagcaattct gaaaaatcca
    16561 gctgatgtgc ctctgctaac ctcttcaaaa gctgtccgat ggattcttga ataatcgtat
    16621 ccataaccca agcctcatca aagggcagct gataggtctg atacaataaa cctagcgcct
    16681 gacgaatagc ctcagaggat tggactagag ttccatcaaa gtcccaaatg agattaactg
    16741 tcacaatcct tacctcttaa atcaatccaa taacgagcaa tagcctgccc tgctaagctt
    16801 gtagtagggt aatcatctgc cacctgaaca atatcctcta aaataccacc agccttttca
    16861 atggtttttc gactggctat attatcttta ttagctgtta ttaagacacg cttgatccca
    16921 cgctcttgat attgctgtaa tgcaaaggcc agcaagtctg tcataattcc acgcccgcga
    16981 taatctgtcc ttgtcacata gccaatatgt ccgccaattg ttgctaagtc tcctttttcc
    17041 aactgccagc gacagcctat tctagccact agctgaccat ctaaaaaata gtaataatta
    17101 gtgctagtgg accagtcagg atgatcagtt tggacctcaa accgtctaga ttgctcaaca
    17161 aaggctgcaa agtcctctac ttttttggtc tcaacaaagg tattacctga agctttttca
    17221 gctaacagta tatcctgaaa gcgcttaaag gctgcttgat cagctaaagc aattgttcta
    17281 atctctttca tgcctggctc ctttttatta tgctaaaaat caactgggca tttctcaagc
    17341 attcatcatg ccaacgaaaa agagctgccc ctagaactgt tgatgtaata ctacgtctag
    17401 aggctgccca caggccttta agctaggctg atagacactg actgctgcta tttaccaata
    17461 gctcaaaacc taagaggaga tggcaactat tagagatgtg cccctcttgc cactaagtcc
    17521 tctagctctg tcaaacgctc ttcaaagacc ctaaaggctg cttctaggta atcaccctta
    17581 gccatatcaa caccagcctt ggcaatcacc tcaagcggat aatctgaatt tccagacttc
    17641 agataggtca agtagtgatc aatatcctct tgagtaccat gcacgatctt atcagccaag
    17701 tagctggctg cagcaaagcc tgttgcatat tgatagacat agtagttgta atagaaatgc
    17761 ggaatgcgag cccactcata ctggataaaa tggttgtcct ctttttttaa gccataatat
    17821 ttttcgttta aatcagcata gagattattg aggtattcac ttgttaacac ctcgccattt
    17881 tgatccgcct gatgaatagc gtgctcaaac tcagcaaact gtgtttgacg aaaaaccgtt
    17941 ccacgaaaac catctaggta atgattcaaa atagcaaagc gctccttatc atcctgcacc
    18001 tcatgtaaca aggcctcagt catgatattt tcattagtgg ttgaagcaat ctcagctaag
    18061 aaaatgctgt aatctccata cacgtaaggc tgtgtttcac gcgtaaaggt tgagtgcagg
    18121 ctatggcctg tctcatgcac tagcgtatag aggttatcaa gcgtgtcctg ccaatttaag
    18181 agcataaagg cattggtatc ataggaacca ccagagtaag ctcctgagcg tttgccctta
    18241 ttgacatgca catcaatcca acgctctgta aaggcacgat gcacacgctc tgaataatcc
    18301 tggccaaaaa cagccaaaac cttctctgct ttttccaagg cctcatcata gccgatagca
    18361 agatctgtct cagataaagg agtataaaca tcatacatct ttagatcatc taaaccaagc
    18421 acctcttgac gtagcttcaa ataacgatga agcagcggca aatgcttatt aacgttttct
    18481 agtagggtat cgtaaacagc ctctgggata aagttggctg acatcgctgc ctgacgggct
    18541 gaagcatatt tgtgaacacg tgccttataa ttttgcacct ttacattggt ttgcagggtt
    18601 ttagcatagg tgtgctggaa ttgctcataa gtactataca tggcttcata ggcagcccta
    18661 cgcaccttgc ggtctttcga ttccatcaag ctaatgaaat taccatgtgt tagctcaacc
    18721 tcttctccct tatcatttgt cacaatagga aaagcaatgt cggcattatc taggatacta
    18781 aaggtctcct cagcaccatt aaagatttct tgtgcccctg ctaatagctc ctcctcagcc
    18841 tgactaagga catgctcacg cgtcttgaac aatttatcaa agaaatggtc atagactgtt
    18901 agctccggtg tctcagctaa gaaggcttgg taggcttcct gacttaaggc cataaattct
    18961 ggctcataga atgaaaaggc ttcactaaat ttagcataaa taccagaggc cttagcttga
    19021 tattcttgat acttggcaac tgtcgtatcc tgatcatttt tcatgctagc ataaacataa
    19081 accttttcaa cacgacgagc cagctccaaa tgcagctctg tgatatctaa gagactgctg
    19141 cttgaatcca acaaatgccc agcctgctgc cttgcagcct caattgctgc cagcagacta
    19201 tctgcctctg tctcccaagc tgcgtctgtt gcaaaaatag tgcttaaatc ccaagtgtac
    19261 ttttcctcta gatgactacg attatctgtc atacggacct cctaagtttc tattactaat
    19321 cattttaaca taatatgctg gtgaaaaaag cttttgcacc tctttatttg ctgcttttgc
    19381 gtaatatttt tcaaagcaat cgtaatagtg gctcaaatcc tcatgaatct ggcaaaagcc
    19441 agctgagcaa gcaatcggct taacctgtgg ataataagcc tctaggggcc tatcaagcag
    19501 gttatcccca gctagataag cctcttcttg ctttttcaac catttgctat cttttgctag
    19561 taaggctttt tgaatccttc tcagcaagtg cttatccatc tggagctgat aggctgacag
    19621 gccttttctt tggtaaggca gccgcaaaaa ggccaacaaa tcatcatcta aggaacaggt
    19681 ctttactaga tagctgacct taccaaataa atcctcatga atc
//
LOCUS       DARYVE010000040        18865 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYVE010000040 DARYVE010000000
VERSION     DARYVE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18865
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            312..2456
                     /gene="pnp"
                     /locus_tag="TVW25_001316"
     CDS             312..2456
                     /gene="pnp"
                     /locus_tag="TVW25_001316"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1378944.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2449..3201
                     /locus_tag="TVW25_001317"
     CDS             2449..3201
                     /locus_tag="TVW25_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1378945.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3213..3749
                     /gene="cysE"
                     /locus_tag="TVW25_001318"
     CDS             3213..3749
                     /gene="cysE"
                     /locus_tag="TVW25_001318"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1378946.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3867..5210
                     /locus_tag="TVW25_001319"
     CDS             3867..5210
                     /locus_tag="TVW25_001319"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1378947.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5203..5610
                     /locus_tag="TVW25_001320"
     CDS             5203..5610
                     /locus_tag="TVW25_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1378948.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5827..6615
                     /locus_tag="TVW25_001321"
     CDS             5827..6615
                     /locus_tag="TVW25_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378949.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6664..7410
                     /gene="rlmB"
                     /locus_tag="TVW25_001322"
     CDS             6664..7410
                     /gene="rlmB"
                     /locus_tag="TVW25_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1378950.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7411..7929
                     /locus_tag="TVW25_001323"
     CDS             7411..7929
                     /locus_tag="TVW25_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1378951.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8113..8973
                     /locus_tag="TVW25_001324"
     CDS             8113..8973
                     /locus_tag="TVW25_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1378952.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9512..9958
                     /gene="rplM"
                     /locus_tag="TVW25_001325"
     CDS             9512..9958
                     /gene="rplM"
                     /locus_tag="TVW25_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1378953.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9978..10370
                     /gene="rpsI"
                     /locus_tag="TVW25_001326"
     CDS             9978..10370
                     /gene="rpsI"
                     /locus_tag="TVW25_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1378954.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10485..11576)
                     /locus_tag="TVW25_001327"
                     /pseudo
     CDS             complement(10485..11576)
                     /locus_tag="TVW25_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11630..12148)
                     /locus_tag="TVW25_001328"
     CDS             complement(11630..12148)
                     /locus_tag="TVW25_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1378955.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12301..12585
                     /locus_tag="TVW25_001329"
     CDS             12301..12585
                     /locus_tag="TVW25_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1378956.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12594..13079
                     /locus_tag="TVW25_001330"
                     /pseudo
     CDS             12594..13079
                     /locus_tag="TVW25_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13131..13418
                     /locus_tag="TVW25_001331"
     CDS             13131..13418
                     /locus_tag="TVW25_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1378957.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13433..13723
                     /locus_tag="TVW25_001332"
     CDS             13433..13723
                     /locus_tag="TVW25_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378958.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13716..14078
                     /locus_tag="TVW25_001333"
     CDS             13716..14078
                     /locus_tag="TVW25_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1378959.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14078..14434
                     /locus_tag="TVW25_001334"
     CDS             14078..14434
                     /locus_tag="TVW25_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1378960.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14778..16322
                     /locus_tag="TVW25_001335"
     CDS             14778..16322
                     /locus_tag="TVW25_001335"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1378961.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16324..18195
                     /locus_tag="TVW25_001336"
     CDS             16324..18195
                     /locus_tag="TVW25_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1378962.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQYRQDLIRLLTWVFGPIKVELGAVCDVVRGNGLQKKD
                     FVNEGYPVIHYGQIYTFYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVG
                     KALVWEGAEDVCIGGHSCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKN
                     LEKAIIILPPVYEQGRIVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            18210..>18865
                     /locus_tag="TVW25_001337"
     CDS             18210..>18865
                     /locus_tag="TVW25_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anticodon nuclease"
                     /protein_id="HEL1378963.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     A"
BASE COUNT         5709 a         3375 c         4301 g         5480 t
ORIGIN      
        1 aggcaggtct ttttttgctg cgtcatcagc ggcttagcgt gcttggctgt agggctatag
       61 tgataaaaga gagtgctgct ggtattgaca gccctttcaa actttttcta ggaatgcctt
      121 ttagggtcgt gaatttttaa ctattttatg gtaaaatgta gcagatacgt cgtttgatac
      181 aaagaggagt gtgtaattcc ttacagattg ctctttgtag caaaacaacg tatagccata
      241 aaaaataaaa ggctagcaag ctttggtcgg gtcaaacggc tatggtaggc tagctcgttc
      301 aaggagaaag aatgtcaaaa caaacattta caacaacctt tgcaggcaaa ccacttgttg
      361 ttgaggtcgg tcaagtagcc aagcgagcaa atggtgccac tgtcgttcgt tatggggagt
      421 ctacagtgct aactgctgct gtcatgtcta agaagatgtc aacaggagac tttttcccgc
      481 ttcaagtcaa ttatgaagaa aaaatgtatg ccgcaggtaa atttcccggt ggctggatga
      541 agcgtgaggg acgtccgtca acagatgcga ccttaaccgc tcgcttgatt gaccgcccta
      601 tccgtcctat gtttgctgag ggctttcgta atgaggtcca ggtgattaat actgtcctgt
      661 cttatgacga agatgctagt gcccctatgg ctgctatgct tggtagctca ttagccctat
      721 cgatttcaga tattcctttt aatgggccga ttgctggtgt tcaggtggcc tatgttgagg
      781 gtgaatttat catcaatcct gataaggccc agcaggaggc ttcattatta gagttaaccg
      841 tagcaggaac aaaagatgcg atcaatatgg ttgaatctgg tgctaaggaa ttgccagagg
      901 ctattatgct agaagcactt ttggttggcc ataaggctat acaggagttg attgcttttc
      961 aagaagagat tgttgcagcg gtgggcaagg aaaaggctga ggtagagcta ttacaggttg
     1021 ctgctgattt gcaggctgag atcatagaga cttacaatgc tgatttgcag caggctattc
     1081 aggttgagga gaaaaaagca cgtgaagccg caaccgaggc tgtcaaggag cgtgtcatag
     1141 ctgcatacga ggagcgttat gcagcagacg aagagcatga ccgtatcatg cgtgatgtgg
     1201 ctgaaatttt ggagcaaatg gagcatgctg aggttcgtcg cctcatcact gaggataagg
     1261 ttcgtcctga tggtcgtcgt gttgatgaga ttcgtccgct tgctgctgag attgatttct
     1321 taccaagggt gcatggctca ggcctcttta cgcgcggtca aactcaagct ttgtctgtct
     1381 tgactctagc cccaatggga gatactcaaa ttattgatgg gcttgagcct gagtacaaaa
     1441 aacgcttctt gcaccactat aatttccctc aatattctgt tggtgagaca ggccgctacg
     1501 gtgcagcagg gcgtcgtgaa attgggcatg gtgctttagg cgagcgcgct cttgcacaag
     1561 tccttccaag ccttgaggca tttccatatg ctattcgtct agtggctgag gtattggaat
     1621 caaacggttc ttcctcgcag gcctctatct gtgcagggac gcttgctttg atggctggtg
     1681 gtgtgccgat caaggcaccg gttgcgggta ttgctatggg acttatctct gatgggacca
     1741 attatactgt tttaacagac attcaggggt tagaggatca ttttggcgac atggacttca
     1801 aggttgctgg gacacgccaa gggattacag cactgcaaat ggatatcaag atcgaaggta
     1861 tcacccctca aatcctagaa gaagccttgg cgcaggctaa aaaggctcgc tttgaaattc
     1921 ttgacttgat tgaggcaacc attgctgagc ctcgtccaga attggcacca acagcaccaa
     1981 agattgatac catcaagatt gatgttgata agattaaggt ggttattggt aagggtggcg
     2041 aaaccattga taagattatt gctgagacag gtgttaagat tgacattgat gaggaaggaa
     2101 atgtttcaat ctactcaagt gatcaggacg ctatcaatcg tgctaaggaa atcattgcta
     2161 gcctagtacg tgaggctaag gtaggagagg tctaccatgc taaggttgtc cgtattgaaa
     2221 aatttggtgc ctttgttaac ctctttgaca agacagatgc gctggtgcat atctctgaaa
     2281 ttgcttggag ccgcactacc aatgtctcag atgttcttga aatcggtgaa gaggttgacg
     2341 ttaaggttat taaggttgat gataagggac gtattgacgc atcaatgaaa gccttggtgc
     2401 cacgcccgcc aaagccagaa aaatcagaag caaaaaaaga aggcaaacat gactaataca
     2461 aatgaactag atattcgttt aagagccttt atcaatgccc ctgataattt tttagatagc
     2521 gtggccttgg ttaatgcttt tcaccagtat ccggtgtggg cagcaaaaaa gccctatgct
     2581 attgagattg aaggggtaag gatttttcct gtattcacag ataaggacga catggcgacc
     2641 tttaaagagg agcaaaagag tgcacaagct cagtattggg tagagcgctc tgctcttact
     2701 gtcttggagg aggctgttca tgcaggtgct gctgggctag gctttaatct caagaaaaag
     2761 ggagattttg gcaattctac agtgttcaag tctgctgata tgattcagtt tatgaacaat
     2821 tacacaacga ttttgaatac cttgatgagt gatgacaata gcgcagcaga taccctggat
     2881 aggctttatc tggtgccggc ctttgtttac cctaaggaag aggagcatta ctatgacagg
     2941 ctttttccaa ccatgtcaac tccagagggg aagcgttatg ttcctgcctt ttcaaatctt
     3001 cagagcttcg ctaaatggta caatcaagag gagtttggcg gcctttttag gaaatcaggt
     3061 ggtgttatct taacatggaa gatagcagac atttatcagc caagaaatgg caataatgac
     3121 atagacgaga cctttggggt tgctattgac ccctttgatg atcagcagat tcttgttgat
     3181 tggtctgata ttgacacata aaaggagttt aaatgggctg gtggaaggac aatattgata
     3241 ttgtaaagca actagatcct gctgcacgta gcaccctaga ggttatccta acctaccctg
     3301 gattaaaggc cttggcagcg cacaggctgt cacatttttt gtggcagcat ggctttaagc
     3361 tgctggctcg aatgcatagc cagttttggc gattttggac acagattgaa atccacccag
     3421 gagctaggat tgcttcaggt gttttcattg accatggggc tggcttggtg attggtgaga
     3481 cggccattgt tgaaaaagga gccatgcttt atcatggagt gacgcttggt ggaactggaa
     3541 aagatcgagg gaagcggcac cctactgttc gtgagggggc actgatttct gcccatgctc
     3601 aaattatcgg tcctgtcgag attgggaaat cggctaaggt tggagctgca gctgttgtgt
     3661 tgactgatgt acctgctggc gtgacggtcg ttggcattcc agcccaaatt gttcgagtgc
     3721 atgagaaaaa gccctcaagg caggattaat agttttctct agaggcagtc agccaaaaaa
     3781 cgggagagtt agagccctat gcttacctca gttgctgaca gcttgcgcag tctaggagaa
     3841 aaggataaaa acaaaaggga aaagtgatga taaaaatcta tgataccatg accagaagtc
     3901 tgcgagagtt tgtaccaata actgataagg tggtcaatat gtatgtctgc gggccaacgg
     3961 tttacaatta tattcacatt ggcaatgcac gttcggctgt ggcctttgat acgattcgtc
     4021 gctactttga atacgcaggc tatacagtca attacatttc aaattttaca gatgtagacg
     4081 ataagattat caaggcagcc aaggaatcag gtgtatcacc caaggaattg gcggacagat
     4141 ttattgctgc ctttatggag gataccaagg cactcggtgt gaagccggcc accaaaaatc
     4201 cacgcgtcat ggactatatg gacgagatca ttgcctttat cgctgcttta atcaaaaaag
     4261 gctatgccta tgagtcggca ggtgatattt atttccgcgt ggcaaaggca tcaaattatg
     4321 ccagactggc taataaaacg attgctgatt tggaggctgg tgctagtggt cgtacagata
     4381 ccgaaactgc tctcaaggaa gatcctttgg actttgccct atggaaatca gcaaagctag
     4441 gcgagatttc ttgggcaagt ccttggagcg ccggtcgtcc tggctggcat atcgagtgct
     4501 ctgtaatggc aaccgagctt ttgggagata ccattgatat tcatggtggt ggcgcagacc
     4561 tggaattccc acaccatacc aatgaaattg ctcaatcaga agcaaaaact agcaaaactt
     4621 ttgccaatta ctggatgcat aatggctttg ttaatgttga caacgaaaaa atgtctaagt
     4681 cactgggcaa ctttgtgact gttcatgatc tgctaaagac ggtggatggg caaacgctac
     4741 gctttttctt ggctactcag cattatcgta agccgattaa ttttactgaa aaagctattc
     4801 atgatgctgg agttaacctc aaatacttga aaaacacgct tcagcagccc acagtagcca
     4861 ctgcagatgc tagccagctt gctgccttta tcactgcctt caaagcagcc atgaatgatg
     4921 attttaatac agcaaatggg attacagtct tatttgacat ggcaaaatgg attaactccg
     4981 gcgcctattc tgaggctgtc aaatcagcat ttgaagagat gctagctgtt tttggcattg
     5041 tctttgaagc agaaagccta gacacagaga ttgagcagct gattgctgag cgtcaggagg
     5101 cacgtgccaa tcgagatttt gcaagggcag atgctattcg ggatcagttg gcagctcagg
     5161 ggatcaagct gttggataca aaagaaggtg tgaggtggat acgtggctaa ttcagttgat
     5221 gtcaatttga ttaatggcat tgcccttgcc tttgttggtg atgctgttta ttcttactat
     5281 attcgtcgtc atctgatttt ccaaggccag accaagccaa ataagctcca ctaccttgca
     5341 acaaaatatg tttctgcaaa ggcacaggct tctctgattc aggccatgct agaagcacaa
     5401 ctattgaccg aaaaagaaaa agacatctac aaacgaggcc gcaataccaa cagccatacc
     5461 aaggctaaaa atgctgatgt agtaacctat cgtatgtcaa caggctttga agctattatg
     5521 ggctaccttg atatgacagg tcagacagaa cggctagaac tgttgatcca gtggtgtatc
     5581 aagcaggtgg agaacagtcc tcaatcataa tgatgaatca tctaaaacat tctctgtgtc
     5641 actagcgatc tgccatcgct caaagtcatg agagtgtttt tatgttgtgt ttaaaagtta
     5701 tgtcacaata tagatacaca cgaaacataa aataaatatt tgtaacaaaa acgtaacaaa
     5761 actattgaaa aattttccga atagtttata atgaaagagt cataataaaa tgataggaga
     5821 atgtctatga aaccaatgag aaacgtagcc ttagttattt cagcaatgtt actgttaagc
     5881 tcacaggcct ttgtatcagc agtagcagca caggacaatc aaccaaccat agcagttcaa
     5941 gcacaggcag cagctgaggc caatgtcagt gctcgtatgc gttcagatca gcccgttatt
     6001 gaagctaaca ttgctaccag tcagccagtt agccaaagca ctgaggctac tattttacta
     6061 aaggatgcca aaggcaacgc gattaatagc acagcctata ccatgcaggc tggtcaaagc
     6121 cggttttcag tatggtttga ccttacgaac ctaaaggtta gtgattatag tatatcagtg
     6181 agtgttcctg ataaagaaaa ggcctttagt ggtagctcag cacctattca ttttgatgga
     6241 aagccaacca aaaatacccc agagacagaa cagaaaaaca gcaatccagt accagctaat
     6301 aaccagccta aacccgctgc tagcggcagg gtgacaagca ctgagcaacc ccaaaatgtg
     6361 cctagcgcga ctgctagcgc caatcatatg acaagaacca atcatcgatc tgataaggtc
     6421 ctaaaggcaa gctcaagcaa cacaccatca gctgccaaat caatagactc tgctgagaaa
     6481 ggcaagggca tgctttctga tagcacagcc caagataaag agcaaaaagg ctttccttgg
     6541 ctgctatcat ctctaattgc aattacagca gctgctttac ttgctcttgt catcaaagct
     6601 gttcacagga aataaaaaga gcagcaagag ctattttatt gctttcgtgg tataataaaa
     6661 accatgaaag ctaaagaaat caatgaaacc aaggatattg tttatggcgt ccatgccgtt
     6721 accgaaagcc tactagccaa tactggaaat aagctttaca ttcaagagga tctgtgtggt
     6781 aagcatgttg atcacatcaa ggatttagcc actagtaaga aggtgtctat ctcttggaca
     6841 aaaaagaaag ctttgaccga aatgacagca ggagctgttc atcagggctt tgcgcttcga
     6901 gtgtcagcct ttgcttatac tgagctagat gagctgctag agctggcaca gcaggaggat
     6961 aatcccttgc tgctcatcct agatgggctg acagatcctc ataattttgg gtctatttta
     7021 agaacagccg acgcaacagg tgtttgtggt gtgattatcc ctaagcatcg tgctgttggt
     7081 gtgacaccag tggttgctaa gacctcaaca ggagctgttg agcatgttcc aattgctcgc
     7141 gtgacaaatc ttagccaagc attggatcag ctaaaagcaa atggcttttg ggtcttcggg
     7201 acagatgtaa ctggtacacc atcatacaag tggaatacct caggcaagct ggctttgatt
     7261 attggcaatg agggtaaggg catttcagct aacatcaaaa aacaggtaga tgaaatgatt
     7321 accattccta tgatgggtca tgttcagagc ttaaatgcta gcgttgcagc tgctattttg
     7381 atgtatgaag tatttagaaa taaattatag atgaaaaaaa gactattgct ggttgatggc
     7441 tataacatga ttgccttttg ggaatcaact cgtcagtttt ttaagacaaa ccaattggat
     7501 caagctagaa ggatcttgct aaataagctg aacaactatg cgcattttga tgatagtgac
     7561 attatttgcg tatttgatgc tcagtatgtt ccaggactta gacagcgtta tgaccaatat
     7621 aggatttctg ttatttttac cgaagaggaa gaaacagctg atagctatat tgagcggact
     7681 gctgctgagc taaacaccgc tctaaccatg gtagaggtgg ctactagtga tctgaatgaa
     7741 cagtggacga tcttttccca aggcgccttg cgtgtcactg ctaaagagct tgagcagcgt
     7801 gttaatgctg ttaagtcgga tttagataag ctgtcacagg atattgatct taaaaagcct
     7861 agactgggtc cctttgatca agggcagctt aatcagctca aggactttat gaatcgatta
     7921 gatgattaat aagcttatct tgctagcttt tctaggtatg attctccagg ctgctagagc
     7981 agctcatacg atctaacggt gatcatttct gaggcagctg gttcttattg ctttcttagc
     8041 tgatattttt ttgttatact atgagaaaat catttgatta ttaaacgata atgacgttac
     8101 ttgggagttc agatgacatt tgtattgatg acagattcaa cagcggattt agattctttt
     8161 tgggcaaagg agcataacat cgatatagta ggcctaactg ttgaatgtga tggcaaggtt
     8221 tacaagacgg ttggtccaga tagattaacg agtgatgctt tgctagctat gatgaaaagt
     8281 gggagccagc ccaaaacaag ccagataaat gttggtcagt ttgaagagat ttttcgacat
     8341 tacgcagctg ataaccaagc tcttttatat atcgcctttt cttcagtcct atcaggtacc
     8401 tatcaaagtg ctgtcatggc acgtgagctg gttttggagg actatccgga cgctgtaatt
     8461 gagattgttg atagcttggc tgcagcagga ggagagggct atttgaccat gctagcctcg
     8521 gaggcgcgtg ataatggaaa aagcctatta gaaaccaaag cgataataga aggtattttg
     8581 cctcgcttac gcacctattt cttagtagat gatctttttc atcttgtgcg aggaggacgc
     8641 ttgtcaaaag gctctgcttt tataggcagc ctagtgaata ttaagcctct cttatggatt
     8701 gatgccagcg gaaaattagt tcctattgcc aagattcgtg gccgtaaaaa ggccattaag
     8761 gaaattgctg acagagccac aaaagatatt gctgattcaa ctgttgttgt gtcctatact
     8821 agtgatcaga ctggggcaga tgacctacga gaacagctat tagcacatga aggtatcagt
     8881 gatgtcttta tgctgccgct cggaccggtg attgctgctc atacaggtcc agatacctta
     8941 gcggtctttg tcatcggcaa ggaaaaaaga taaaaagaaa aggattgaag cgcttgtttc
     9001 aattcttttt tgtcgactat agcttgtttt agctgtgatg ccgcttaaga gtatgggtgt
     9061 tcgcattttt tatttttaat caaaagttag aatgaattgt ttgacaatga aggtgcgcgt
     9121 gcaggtaagg aactagcata acagaacagg gctttttgat ttgccagaag tcagatgtca
     9181 aatgttttag cagttgacag gagctttggt cattccacca ctaatctttg tattgttatt
     9241 tgcataggag ctaacaggaa ctgagcggat tttttggagg gaagtcaagg ctaatagtcc
     9301 agctcaaaag caagcctgtt cttcttgtga aaaagcaaaa ataatcaaag aaatagagct
     9361 aaaccacttg actatcagtt aagaagtttg atactatagt agacggtatt gtttacccca
     9421 tttgaaaggc cccggaacct tccaaatacc ttcgatggac cggaacatcc atcactaatg
     9481 taaacaaaaa cgaattcgta taggagaaat catgaacaaa acaactttca tggctaaacc
     9541 aggccaagtt gaacgcaaat ggtacgttgt tgacgcaaca gatgtgccac ttggacgcct
     9601 ttctgcagta gttgctagcg tacttcgcgg aaagaacaag ccaactttca caccgcacac
     9661 tgatacaggt gactttgtta ttgttatcaa tgctgagaag gttaaattaa ctggtaaaaa
     9721 agcaactgat aaggtttatt acactcactc aatgtaccca ggtggcttga aatcaatcac
     9781 tgctggtgag cttcgctcta aaaatgccgt tcgtttgatt gaaaagtcag taaaaggcat
     9841 gcttccacac aacactcttg gacgtgcaca aggtatgaaa ttaaaggtct ttgttggcgg
     9901 tgagcacact catgctgcac aacaaccaga agtacttgat atttcaggac ttatctaaga
     9961 gaaaggagca ttaaataatg gcacaagcac aatatgcagg tactggtcgt cgtaaaaacg
    10021 ctgttgcacg cgttcgttta gttccaggta ctggtaaaat cactgttaat aaaaaagatg
    10081 ttgaagaata catcccacat gctgacctac gtttagtcat taatcagcct tttgcagtga
    10141 cttcaactga aggctcatac gacgtttttg ttaacgttgt aggtggtggt tatgctggtc
    10201 aatcaggtgc gattcgtcat ggtatcgctc gtgcgcttct tcaagtggac ccagatttcc
    10261 gtgactcact aaagcgcgct ggtcttctta cacgtgacgc acgtatggtt gaacgtaaaa
    10321 aaccaggtct taaaaaagcc cgtaaagcta gccagttctc aaaacgttaa tatccagtta
    10381 taccaacgtt tcagagcact ttgcgaagtt ttcgcaaggt gcttttttgt tgaaaaaagc
    10441 accttggtaa tctgttgaga cctagtttta agagaggtta agttagaatg actataagta
    10501 tctaaagtca tctggctgct agcatgacct agacgcttag cggtattaac tgggtcaatt
    10561 cccatttcaa tcatcaaggt tgcgtgagtg tgcctaaacc catgtgggct aatcttttta
    10621 agattatgct ttcgtataat gcgttttaga atattgttga tatagtcagc gtgtaagggt
    10681 tctatctcac catctctgtt gcagtatgta aacataaatt ctttgtcgag agaaaggggc
    10741 tgtactgata attgcccctt ttctttgcta gtttcctgtt tccatttgtt gaggatagaa
    10801 caggtttcat catcaagata gatagagcgt actgagaatg tatttttagt tcctttttca
    10861 atggcatgac catctattct tcctaaactt ttgctgactg ttaatagttg attctcagaa
    10921 tcaaaatctt cccatttgag ggcgtagagc tctccttttc gtaacccgct gtatgctagt
    10981 aatcgaaata gagcataatg tttataaggt tcattttcta aaatgattgt caaaaaatga
    11041 tgcaactcgt taactgtcca gtagttctca ctgacagttt ttttgagttt aggcataata
    11101 actttgctca taggattacg ttcaatatga ttcatattga tggcaaattc aaaggtttta
    11161 gaggtgtatg acttgatttg cttcatgttc ttgaatgatt tcgctttatc tgtgataaag
    11221 gtttggcagt ctagcggact gatttttgaa atctttttct ctccaaaggt tggaagaata
    11281 tgaaggcgat ataaatcggc cgttttagct gcagtagttg tttcaacggt atctttgtaa
    11341 gcttcatacc acctttgata tagttcttgg taagtatagg ttgtttgagc agtaagatgg
    11401 gcaaaagttc cactattcag ctgatgatta acagcagttt catgagcttt ggcagcttta
    11461 cgcgtcttga atcctcgttt agtgtaatat tttttcttac cgtagtcgtt tagaccaagg
    11521 taaactttaa caaaataggt aattcctttt gtagattggt atttgtgtac agacataaca
    11581 gttctccgtt tctaagtttt cggagcttat gtaattgaga aatattagtc tattttctgt
    11641 cacgatctgc tcgtctaatt tgaaactctt cggtttgtat ccatgttttc caaatatccg
    11701 atttttggcc ttggttattc ataaacttaa ttaagtcttt gataaaggtt tcttcataat
    11761 ccattaagta gttagaaaga atacgtctaa agtcatctga gaaaacctcg tttaagggca
    11821 tagacaaatg aatctctcct agttcgattc ctttcttaag cttctccata tcgcttttaa
    11881 aaggtgttac agaagtaatt tcagatgtct tgaaactatc agtgacgatt tttaaatttg
    11941 acggagcgta cttttcttcg tcaattccaa ggatgtatgc cactgagaca ccaaaataat
    12001 ccgctaactt ttgagcattc tcttttttag gttttcgtat tccttggtta tagctagata
    12061 gtgttgggta ggatatatct agcgcttcac tgatactttt tatttttttg ccactttctt
    12121 ctataagttt agctatatta ttagtcatag attcctccta attgatattc taccacattt
    12181 aatacaaaaa gtataatacc acttgacaag aatacaaaaa gtatttataa tttaaaatgt
    12241 ataataaaat atacaaattt cggagtttat ttaattgaga aatggaaacg aggtaatgat
    12301 atgtctgaag aagcgacttt agttgttcaa cttcccaaag ttttggaaaa acaattaagg
    12361 gcacattatg atgaaatggt ttctacagct attgaaagag cgctagagga taaagaatta
    12421 tataaaccta tggttcggat ggcagccctt tctagatggc ttgatgtgtc aacgacaaca
    12481 cttcaaaagt ggacgcgaga aggaatgcct acaatggtta ttgatggtgt gactctgtac
    12541 gataaacgtg cggttacacg ttggttgaag caatatgaaa gatgaggtaa agaatggcta
    12601 atagacgaat gttgagtaaa acggtggtgc agatacaacg atttttacgc ctaccacttg
    12661 aagcgcaggc gctttactgt cacttggtag tcaatgcaga tgatgatggt attgttgaag
    12721 cttttcctgt tatgcggatg attaatgcta atgaggacag tttgaattta ttaactctta
    12781 agcagtattt actcttgtta aacaatgaaa tggtttactt tatcaaggat ttctttgagc
    12841 agaataccat caaagcagat cgttacacac cgagtagtca tcgtcaactt cttatagatt
    12901 atctgaagga taatcagttg ttggagtgtc taaatctagg accacgcttg attaattatc
    12961 ttcaaaatac tcggctccaa gttggagcca gtctggatcc agatgggaac cgcaatataa
    13021 ttaaagataa gataagtaaa gataggatag gtaaagataa gttaagtcaa gataagatag
    13081 gattagataa tgatccaatc tcatcacaac tgactgatga catctggtta atggaaacac
    13141 tatggcatcg agaattaacc caacaggaga aagtattatt agaaggattc gcggttaatg
    13201 attctttatt gcagttagct attcagaaaa cagaggagct tgagccaaag aaacaaaaca
    13261 tgagttatgt caaagggata ctaatgaatt gggaagctag agggtttata actgttgacc
    13321 aagtgatagc atctgaagaa gactaccgtc cattagaaat tgcaaatgta gaagtttcag
    13381 aagatttctt agcagctatg gatatatgga aagactaggg gaataatgag ttatgacagt
    13441 atattatcaa ttagaaaata tgttagtggc tgggtttaag tcacaagatg agtacgaccg
    13501 ctatcaggct ctcaagaggg actatgaagg ggagtcagag gactatagct tttcaatcag
    13561 agaaatcaca aatcaacttg aaatcatttg tcagacctca gagaatgatt ttccgaactt
    13621 atcagaagca ttaatgattg attatttaga actggtagga gagttgaaac gatatgatac
    13681 taatcaggca gacaggtatt tagggatggt tcgtcatgtc tgaacgtatc agaactattt
    13741 taaagaagtt ttatgtgacg gaattgcaga atgaagtact taatcaacta gtaaatgata
    13801 caggcttgca aacattctct aattatgctc gtcggatgct ttttaaggaa acatcactct
    13861 ttatgcgatt tgatgaatct cagtttgatg agttgattta ttctttaagg cgtattcaaa
    13921 ataatttaag gcagttatct aaaattgcag agcagtctca agatagtcaa gcctacagag
    13981 ctatggacta tagcagaagg ttagtttcac attatgaaaa gcagttaacg cgttaccaca
    14041 agaaaaagaa acggaaatta ttatctaagg gagcttaatg gataaaagga gaattaggaa
    14101 cgtaattaaa caagtctttt tgtctgaaga agaaaatcaa aaactgttag agaaaatgaa
    14161 gcaagatggc ttcacaaact tttctctttt tgctagaaag caattattaa aacctgattt
    14221 tgaaacttgg ctagttagtt ttccagaata tcagccgctg actggcaggt tactatctgt
    14281 tggtagaaca attaatggca tcgctaaaag cgcaacacag tttggaaaaa tttcccaaca
    14341 tgatttgatg gaattaggtc agttgatgga ggaacttgta gaactggtag agaaacaagt
    14401 gaaggaagac aagcaacgaa tagccaagaa gtgatagtcg ttcagtcatt ttggtagaat
    14461 agttttaaat aaaacaacaa aaacgctgat ggtagtcagc gttttttagc atgtaattgt
    14521 aaaaaatcct tgtacggaca atgtgcggca ccgtataaag tacgggaaat cactaaaaat
    14581 ggagttaggt ctttgcgagc tcagatagtg tatacacact atcgtaaaaa tagaaccatc
    14641 agtaaaggtc agactgacac tttttgattg atgcttatat tttattttgg ggcaaagccc
    14701 caaacccctt gagaaaacgt gtgagaagta gggaaaaatg gtataataga aatattaaag
    14761 actgtgagga tttgaagatg tcagaacaag cacaaaggca agagttgcac cgcaaaatct
    14821 gggcaatcgc agatgatgtc cgtggtgcgg tagatggttg ggatttcaaa caatatattt
    14881 tgggaatcct tttttaccgt tttatcagtg aaaatttcaa gacttatatc gagggtggtg
    14941 aggacttcaa ctatgaggag attccggatg aagtaatcac acctgaggtt aaggatgatg
    15001 cgattaagac aaaggggtac tttattatgc ctgcgcagct tttttccaat gttgtgaaaa
    15061 cagctcgtag taatgacaac ttaaatacgg aactcaagga tatttttgat gccattgagg
    15121 cgagtgctat gggttatgcc agtgaaaatg atattaaagg tctttttgat gacgtagaca
    15181 ccagaagtaa taagctagga agtaccgtcc cagagcgtaa tgaacgctta gcccttatcc
    15241 tagaaggtat tgccagcctt gattttggta gtttcgagga caatcatatc gacctttttg
    15301 gcgatgccta tgagtttctg atttctaact acgcttctaa cgccgggaaa tcaggcggag
    15361 agtttttcac accgcagagc gtgtcacggc tcctagcacg tatcgtcatg ttaggcaagg
    15421 atgaaaagaa caaaatcaat aagatttatg accctgcttg tggttctggt tctctcttgc
    15481 ttcaagccaa aaaacaattt acggagcata ttatcgagga tggtttttat ggtcaggaaa
    15541 tcaacatgac cacctacaac ttggctcgga tgaatatgtt ccttcataat atcaactacg
    15601 acaagtttag cattgagcgt ggcaatacgc tgctggaccc taagcatggc aatgataagc
    15661 cctttgatgc tatcgtgtcc aacccgcctt attcaatcaa gtgggttggt agcgatgacc
    15721 cgacgctaat taatgatgac cgttttgcac cagcggggat tctggcaccc aagtctaaag
    15781 cggattttgc ttttatcatg catagccttt cttatttgtc caataaaggc agagcggcta
    15841 ttgtgacctt ccctgggatt ttttatcgtg gtggagcgga gcaaaagatt cgtcagtatt
    15901 tggtagacgg aaactttgtc gaaactgtta tccaattgcc ggataatctc ctttttggga
    15961 cgtctatcgc tacctgtatc cttattcttg ctaagaataa gccgacaaca gatgttctct
    16021 tcattgacgc tagccagcag ttcaaaaaag aaaccaataa caatgtcttg acagaagaga
    16081 acatcgagaa aattctgaaa agtgttgagc ataagaataa tgaagagtat tttgctcagc
    16141 tcatttccca agaaaaaatt gtggaagctg actacaatct ctctgtatct acctacgtgg
    16201 aaaaagagga tacgcgtgag aagattaata ttgatgtatt aaacaaagaa attgctgaga
    16261 ccgtgaaaaa tattgaccga ttgcgggcag agattgataa gattgtcgag gagttgagct
    16321 gatatgacct acattgatga gatgattaaa gagctttgtc ctgacggagt ggagtggaaa
    16381 gagttgggtg aagtcgttga ctacgaacag ccaacaaagt atatcgtaaa atctaaggaa
    16441 tacagcgatg attattccat tccagttttg acagcaggtc agacatttat tcttggatac
    16501 acaaatgaag taactggtat ttatccagca agtaaggaac atccagttat tattttcgat
    16561 gactttacga cagctagaaa gtgggtggat tttgaattta aagttaagtc ctcggcgatg
    16621 aaactactct ctatcaagtc agaccgtcaa gatgatgttt caataaggta tgtttggcac
    16681 tatttaggaa caataaaata cacaccagaa cagcacgcac gacagtggat agggactttt
    16741 tctaaattta aaatccccct tcccccacta gaaattcaag gggagatagt taaaatactt
    16801 gacaaattca cggaacatgt tacagaattg accgcagaat tgaccgcaga attgaccttt
    16861 cgacagaaac aatattctta ttttagagat aagctcctaa gttttgatga tgaaagtatg
    16921 ggaggggcga acgataaggt ttacactgtc cagtggaaaa cgctggggga ggtggtgaat
    16981 tttaggagag ggtctttccc tcagccttac acagatatgt cgttctatgg tggagaagat
    17041 gcccaaccat ttgttcaagt tgtagatgtt gctgatgaag gatttagact gaatactaaa
    17101 acgaaaaaaa caatttctca aaaagctatt ccaaaaagtg tttttgtacc taagggaacc
    17161 gttatcgtta ccttgcaagg caccctagga agggtagcgg ttacccagta tgatgcttat
    17221 gtcgatagaa cgttagcaat ttttgacggt tataagcaag aagttgataa acgctatttc
    17281 gcacaccaat tgaagtttat ttttgacaga gaaaaagaat ttgctagagg aagtactctg
    17341 aaaacaataa caaaacaaga attctcgaat ttcaaaatcc cagtccctcc tctggatatt
    17401 cagcgtcgta ttgtccaagt tttggataat tttgatacgg tttgtaatga cctaaatatc
    17461 gggctaccta aggagattga gcttcatcag aaacagtatg cctattttag agacaaactc
    17521 ttgaccttca ccgccgaagg cgtgtatact gacagtacag tacagtacag acaagaccta
    17581 attaggctct tgacttgggt ttttggaccg attaaggttg agttgggggc tgtctgcgat
    17641 gtggtgcgtg ggaatggttt gcaaaagaag gattttgtta atgagggtta tcctgttatt
    17701 cattatggac aaatctatac cttctatgga ttgagtgctc gcgtgacgaa atcttttgtg
    17761 tcaccagaag ttggtcaaaa attgaaaaaa gctaaaactg gtgatgtgat tgtagctact
    17821 acttctgaaa atattgaaga tgttggtaaa gcacttgttt gggaaggtgc tgaagatgtt
    17881 tgtattggtg gacactcttg tgtattgcac acggaacaaa actcgaagta cttgctttat
    17941 tattttcaga caactgtgtt tcaaaagcaa aaggaaaagt tagtgatagg aactaaagtg
    18001 attgaactgt atcctaaaaa tttagaaaag gcgattatta ttctcccacc tgtatacgaa
    18061 caagggcgta tcgtctccat tcttgacaaa tttgatacac taacttctga ccttacccaa
    18121 ggtcttccga aagaaattga gcaacgacag aaacagtatg agtattggcg ggatttacta
    18181 cttaactttc cgtaggagga agaatagata tgggaaatga tatcaaattt gaaaatttag
    18241 aacagatttc ggataatatt atttctagta ataagaaagt tcatttgcta tatgcctata
    18301 atgctactgg gaaaactagg ctttctatgg aattgaaaaa taaggtaaat gagactgata
    18361 gtgatggtaa tagcattaag cacattttat atttcaattc atatacggag gatcttttta
    18421 cgtgggataa tgatttggaa aacgatgaag atcgatattt gatttatgat aaacgaactt
    18481 attttggaaa tttccttgaa gagcaacaac ttttcgaacg tgctgtagac aattttcaaa
    18541 agtatgttgg tagatctatt gatattgagt tccaagatgt tattgaaaca gttaaagatg
    18601 agttcggaaa tgttcaaaaa gataataggg gtgaggcact aacaattagt aataaaaaga
    18661 gtataagatt taaagtagat gggcatacaa taaaggtgtc tagaggagaa gagaggattt
    18721 ttgtttggtc agttttctta acgctccttg aaattattat tgaagatttg actgagtctg
    18781 ctgatacctc agaattttca aaaatgaact atatctatat tgacgatcct atatcttctt
    18841 tggatgatac taatattatt aatgc
//
LOCUS       DARYVE010000041        18638 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYVE010000041 DARYVE010000000
VERSION     DARYVE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18638
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            12..2231
                     /locus_tag="TVW25_001338"
     CDS             12..2231
                     /locus_tag="TVW25_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1378964.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            2564..3769
                     /locus_tag="TVW25_001339"
     CDS             2564..3769
                     /locus_tag="TVW25_001339"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1378965.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            4085..5344
                     /locus_tag="TVW25_001340"
     CDS             4085..5344
                     /locus_tag="TVW25_001340"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1378966.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            5759..7303
                     /locus_tag="TVW25_001341"
     CDS             5759..7303
                     /locus_tag="TVW25_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1378967.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            7387..8415
                     /locus_tag="TVW25_001342"
     CDS             7387..8415
                     /locus_tag="TVW25_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1378968.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            8436..10226
                     /gene="uidA"
                     /locus_tag="TVW25_001343"
     CDS             8436..10226
                     /gene="uidA"
                     /locus_tag="TVW25_001343"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1378969.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            10268..10939
                     /locus_tag="TVW25_001344"
     CDS             10268..10939
                     /locus_tag="TVW25_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1378970.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            11122..11739
                     /gene="eda"
                     /locus_tag="TVW25_001345"
     CDS             11122..11739
                     /gene="eda"
                     /locus_tag="TVW25_001345"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1378971.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            11767..13164
                     /gene="uxaC"
                     /locus_tag="TVW25_001346"
     CDS             11767..13164
                     /gene="uxaC"
                     /locus_tag="TVW25_001346"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1378972.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            13426..14520
                     /locus_tag="TVW25_001347"
     CDS             13426..14520
                     /locus_tag="TVW25_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1378973.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            14536..15375
                     /locus_tag="TVW25_001348"
     CDS             14536..15375
                     /locus_tag="TVW25_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1378974.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            15639..16442
                     /locus_tag="TVW25_001349"
     CDS             15639..16442
                     /locus_tag="TVW25_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1378975.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            16557..18347
                     /locus_tag="TVW25_001350"
     CDS             16557..18347
                     /locus_tag="TVW25_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1378976.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
BASE COUNT         5172 a         3537 c         4540 g         5389 t
ORIGIN      
        1 atggaggaaa gatgaaaagt aaaaaattaa tgctaatggc tagcctgttt atggcttgtc
       61 acctgaccct gacagcttgt cagtcgacaa agcagccaac aaatcagcct aagacaaaac
      121 agacagctaa aaaagcgacc aaaaagaaac agtctaaaaa ggttaagcaa acaagaaaag
      181 accgtaaggg agtagcgggg attgactttc caactgatga cggttttatc ttgaccaagg
      241 attcaaaaat cttatctaga acagaaaacg gtattgttgt tgagcataat gggcattcgc
      301 attttatttt ttatgcagat ctcaagggca gcaagtttga gtacctgatt ccaaaggacg
      361 ctgacctaaa caagcctgag cagaccaagg cagcatcagg tcatcaccat actagtgcta
      421 atgacccgca ccatcactat gtgtttaacc cagctgatat tgtagctgag gacgccttgg
      481 gctatattgt ccgtcatggt gatcattacc actatatcct aaaaagctca ctaggtggtc
      541 aggtagctta tccagtgcct aaccatgtgc cactatcagc tccatcatca ccgtctggaa
      601 aatttgcagg tgttgattac ccaacaagtg atggcttctt gtttgacggg acaggtattg
      661 tcggtcgaac atcatatgga ttgattgttg atcacaatgg ccacaatcat ttagtcactt
      721 atgaaagctt gcgtaacagc aagtggaagc atttaatcga acagccaaag gaagaagcac
      781 cagctaagcc acaaagtgat cttgagaaaa cgattgcttt gaaaaaagca tatttggcta
      841 agtcattaaa tattcctgag gacagcattc gtgtggagca tacagaagaa ggtatcattc
      901 ttgactatcc acatggtgac catcgtcatg caacctatat tgacgatatt gatttatcaa
      961 aaccttttga tcctcatgca gtagatccgc atgctaagga tagaatcggt atggcaactc
     1021 tgagaaagct tggctttgat gaggaagtga tttcgtccat tatccatgca aatgcaccaa
     1081 ctgagtttcc atcaagagag cgagacctag agaaaatgaa ggcatggttg gcgactgttg
     1141 aatacctcaa tatcggtgag attaaggatc ctcttaagcg ggcaggttta aacctgatgc
     1201 ctaatataca gattttaggt attggcttta ccccaatcac tgatattacc ccagtctacc
     1261 agttcaagaa cctcaaacaa ttgtggatga cacagaccgg cattaaaaat tatgatttct
     1321 tgaagaacct gccaacgctt gaaggaattg atatttctca aaatggtgtt tctgatttga
     1381 gcttccttaa agcctttccg cattacaagg taatttcggc agcaggaaat gatatcacag
     1441 atatttctat tttgaaagaa ttgccaaacc tagagtccgt taaccttgac tttaacaaga
     1501 ttacagatct ttctgccttg gcaaatgctc aaaagctagt cgctgtcagc ctagagcaca
     1561 atcagattaa ggacttgagt gccttgtcaa acaagggaca attgaccaaa ctctttgtgt
     1621 caaacaaccc tgaccttgat ttgtcaacct taaaatcctc tgctctcaag gaaatcactg
     1681 ccaaggaggt taatttacaa agccttagct ttgtcaagga tctaccggca ttagagcagc
     1741 tagtggttga ccaaaacaag cttaacagct tgacaggtct tgagcacaat aagagcctga
     1801 ttcagctatc agctaaccag aacatgatta atagcttggc cttaccaggt acacaaagct
     1861 cattacagtc tcttaacctt gaagagaacc agctgactaa ttttgagggt gtcaacaatt
     1921 atctcgccct agaagcaatt aatgttaatc gtaacaagat taacaccttg gccttgaagg
     1981 agcctaacca aaccctgaaa tacattcagg ctgatggtaa ccacttccca gctgaggagc
     2041 tagctgctga aagcggacaa ttcccacaag gaattatcaa gaacttcaag gcagcagagg
     2101 gtggtagtct aaataatgcc acaccagcag aagctgttga agacgagcat aagccggctg
     2161 atactgatca agaggcagca gataagcatg accatgagca tcatgatcac gatgagcacc
     2221 accatggtta atcgatagct tgcgctgatt atcacgacat taagaggagg aatacgcctg
     2281 tagcggtatt ccttttctta ttttgagaaa aaagctgatg gagctcttac aaatcccgct
     2341 aaaagtggta taataaataa gttattaagt cccgataaga cggctttgtt atctgaggat
     2401 agcagtctaa aagccggtac tttgtaactc gctaagcgtt agtcataggc tagcttggat
     2461 acagtccttt tgtattggcg gctggcttga tgagtgaggc taggaaaatc ctatctggca
     2521 tgtgtgctgg tgggtatcat tctttttaag gggggacatt tttatgtcag aacgtaaact
     2581 tttcacgtct gaatcagtat ctgaagggca tccagataag attgcagacc aaatttcaga
     2641 tgctatttta gatgctattt tagccaagga tccagaggca cacgttgctg cagagacctg
     2701 cgtttacaca ggctcggtcc acgtttttgg agaaatttca acaactgcct atgtggatat
     2761 taatcgtgtg gttcgtgata ccatcgctga gattggctat actgaggcag aatatggctt
     2821 ttcagcagaa tcagtgggtg ttcatccatc tctggttgag cagtcaccag atattgctca
     2881 aggcgttaat gaagcacttg aagcacgtga aggacaaagc gatgatttca atgcgattgg
     2941 tgctggggat caggggctaa tgtttggctt tgcaattgat gagacaccag aactaatgcc
     3001 actgccgatt tccttatctc accagcttgt acgccgtttg gcgacactgc gaaaatcagg
     3061 tgagatcagc tatttgcgtc cagacgctaa atcacaggtt acggtcgaat atgatgaaca
     3121 tgataagcct gttcgtgttg atacagttgt tatatcaacc cagcatgatc cagaagtaag
     3181 caatgaccag attcgtcaag atatgattga gcaggtgatt aaggctgtta ttccagccca
     3241 ttatctagat gagaagacaa gattccttat caatccgact gggcgttttg ttattggtgg
     3301 tcctcaggga gattctggct tgactggtcg taagatcatt gttgacacct atggtggcta
     3361 tgcgcgtcat ggtggtggtg ccttctctgg taaagacgca actaaggttg accgctcagc
     3421 ctcttatgca gctcgttata ttgccaaaaa ccttgtggca gcagggcttg caagtaaagc
     3481 agaggttcaa ttagcctatg ctatcggggt tgcacagcca gtttcagttc gtgtggatac
     3541 ctttgggaca tcaacagtgt cagaaagtat tttggaagcg gctgttcgtc aggtctttga
     3601 cctgcgccca gcagggatca ttaagatgct tgatctcaag cgtccaatct ataggcagac
     3661 agcagcctat gggcacatgg ggcgaacaga cattgacctg ccttgggaac aattggacaa
     3721 ggtatctcca ttgacagaag cggtggcagc actgtcagag ggtgcttaag cagattgagc
     3781 gccggttagt tgatgattga cttaaaggta taatagctcc tgagctagcg gctgtgctgc
     3841 tggttgggag cttttttagt ccagcaaaac ttgtcaggct tggcggctat gaaagacaaa
     3901 aaggcctgcg cagcagaaga aagatccaga taagagtctg gcttctcaaa aacctgttat
     3961 gaaaagtgat caagaggcag gttgttaagc ctgttgcagc agctggtgat gaggtgattg
     4021 taatagaccg ctatttgtga taaaataaaa aggttgaatt ctagtatcag aaagttttga
     4081 aagtatgcga aaaattatta ttaatggtgg aaaagcctta tccggagagg tggcagtttc
     4141 aggcgctaaa aatagcgttg tagctctcat tcctgcgatt attttggcag acgatgttgt
     4201 cactttagat ggggtaccag ctattagtga tgttgacagt cttattgaaa tcatgaagct
     4261 catgggagct atggtgacct atcaggggga taccttggag attgacccca gaggggttca
     4321 agatattcct atgccttatg gtaaaattaa cagcctaaga gcctcttact atttttatgg
     4381 cagtctattg ggacgctttg ggcaggcggt tgtgggcttg ccgggtggct gtgacttagg
     4441 ccctaggcct attgatcttc atctgaaggc ttttgaagca atgggggccc agatatctta
     4501 tgagggagca agcatgcacc tgatgacaga ggctcagcag cttcatggcg ctcatatcta
     4561 catggatact atcagtgtag gcgctaccat taatactatg attgctgcga caaaggcaaa
     4621 gggtaagacc attattgaaa atgcagctag agagcctgag attattgacg ttgcgacact
     4681 gttaaataac atgggggcgc atattcgtgg tgcaggtact gatgtgatta cgattgaggg
     4741 agttgaaagg cttcatggca ccagacatca ggtgatccca gatcgcattg aggctggtac
     4801 ctatattgcc ttggcagccg ctgttggtag tggggtaagg attaccaatg tcctttacga
     4861 gcacttagag agctttattg ctaagctaga ggaaatgggt gtgagaatga cggttgaaga
     4921 ggattctatt tttgtggaaa agcaggaagc cttgaaagca gtcactatta aaacctctcc
     4981 ctatccaggc tttgccactg acctacagca gcctttgact cctctgcttt taaggactga
     5041 gggtcgtggt agtatcattg atacgatata tgaaaagcgt gtcaaccatg tgccagagct
     5101 tgctcgtatg ggagcagata ttgccattct tggcagccaa attgtttatc atggctctaa
     5161 tcgcctcagt ggggcacagg ttaaggcaac tgatttgcgg gctggtgctg ctttggtgat
     5221 tgcaggtcta atggctcagg gtaaaaccga gattagcaat attgagttta ttttacgtgg
     5281 ctatgctaac attattgata agctaacagc cttaggggct gatattcagc ttattgagga
     5341 ttaagaactg aaggctttca tagcctaatg attatcacct gacatgaatg cttagagctc
     5401 ctaagactgc ttggtatgag agtggtttta ggggcttttg atttttaaga accccctgtc
     5461 tatcctgtgt actgaccccc aaaagttgga cacgacatat tagtgaaagg atttagttct
     5521 gtattgcaca gggctcagtt tttttgatgt caatgagtaa ttgtctgatg attattttta
     5581 aagacaccag aaattatcag atgaatttaa tgattaaaat cctaaataag ctttattttt
     5641 taaaattagg cgaaaaaagt ttaaattgtg ttgacaaatc atcagatgaa tagtaagata
     5701 agcatgtaga aataaaacgc ttacacaata agcgaatgat aaaaggggga tttctctgat
     5761 ggagaaaaca attgaccaaa gggttgaaga ggttacctat aaccgcgcta aggtttggca
     5821 gcttgtttta tttgctttaa acaatgcttc aaccaatatc tacctattca catttatgtt
     5881 tgtgacctac ttttcaacag gtgttctagg cttggcagct atttttgtca gccagatcat
     5941 gggttatatt cgtatttttg atggctttat tgatcctgcg attggtatct tgattgataa
     6001 aacagaaact aagtttggta agtatcgtcc gatcctaatc atcggaaata ttatcacagc
     6061 cctatcactt attctgctgc ttggtctaag tggagttagt gagaacattc gttttccact
     6121 ttttattctg gttttgatta tccataagat cggctactct atgcagcaaa ccatcactaa
     6181 ggctggtcag acagccctta ctaatgatcc gaagcagcgt ccaatcttta acattgttga
     6241 tgccattatg acaaccttgc tgatgactgg tggacagttt gttgtgtcaa gcttcttggt
     6301 tccaaaattt ggtaacttca caccagcctt cttccacgtg ttgatttatg gcacgattgt
     6361 tatctcagct attttgggtc tattggcagt gcttggtatt tggagcaagg acagaaagga
     6421 attctttggt cttggtgaaa atacgcaaaa gacagctctg aaggactatt tgaaggttat
     6481 caagggcaac cagccgctac aggtcctatc aattgccgca gccttggtta agtttgctgt
     6541 tcaattcttt ggtgattcgg ttgtcatggt tatcttgttt ggtgttttat ttggtaacta
     6601 tgctttgtct ggtcaattct cattgctgtt tattgttccg gggattttga ttaatattgc
     6661 tttttcaggt attgctcgta agagaggttt gcgtttctca tatatcagag ctcttcagat
     6721 tggcttggtt ggcttgttag cctttggtat tgtgctcttt atgggtaata aaggggatct
     6781 cagcctaagt catattaacc tttacactat tttgtttact gtgacactga ttattgctcg
     6841 ctatgcctca caagcgcctg ctagcttggt gctaacaatg ggagctgata tttcagacta
     6901 cgaaacatca gaatcaggcc gttatgtctc aggaatgatt ggtacaatct tctccttgac
     6961 tgactcgatt gcatcatcat ttgcgccaat ggttattggt gcagtgctgg ctggtattgg
     7021 tttttcaaag acttacccaa cgattgagac accgcttacc ccaagtctaa agatggcctt
     7081 gattgcgctg catgtcggta ttccatttgt agccttacta gtggctttga ttttgatgtc
     7141 attctacaag cttgacaaag aggaaatggt gcgtattcaa gagaagattc aagtgatgaa
     7201 agcaagctct gataaggaac gcgtgcaggc tatcgctaaa aatgtaccac tgtcagacat
     7261 ggactatgtt gatgtgacaa aatatcctgt tgataaggat taggtgctgg gtcagctatt
     7321 tctttgagga gtggctgact tttttataaa ataatagagt agcttgatag tataaggagg
     7381 aatgttgtga aaaaagttgt atccttgggt gaaatcctct tgcgattgtc accccctcaa
     7441 taccagacgt taaagcaggc aacaagccta gattgtcaat ttggaggttc tgagcttaat
     7501 gtcatctcaa gccttgctca gctagggcat caggtctctc ttatttcagc tattccagac
     7561 aatgatctgg gacaaatgac aaaaaccttt ctcttttcgc gtcaaattaa tcaggagcat
     7621 attatcgaaa agggtcagcg tttagggctt tattattatc aaaagggctt ttctttgcga
     7681 gcaagtcggg ttacctatga ccgctgtcat tcagcctttt gggagtcaaa gcgtgctgac
     7741 tatgatttgg agcatgtttt tgatgaggct gattggtttc atgtgtctgg gataacgcct
     7801 gctctaacga gtgatcttta tgagctgacc tattatttga tgacaaaggc tagggcagag
     7861 ggattgacta tttcctttga tttgaatttt agggctagtc tatggtcctc ctttcaggag
     7921 gctagagatc tcttgtcgcc tcttgttcag ctggctgatg tttgtattgg cattgagccg
     7981 ctgacgctta agggaagcgg cgcgcttgat ttaaaggatc aattaggctt gaatagaccc
     8041 tatgatgatg aagccttgtt gaaggaggtg ctggctaggt tagctgatac ctatggggta
     8101 aaatgctttg cctttaccca gagagagatg gactatacca atgaatacct gttaaaggcc
     8161 tacctgtatc aaaatggcag cctttataaa acccaaaaat ctggtattca ggttctggac
     8221 cgagtaggga cgggcgatgc ttttacggca gggctgattc atggcttatt aagttataaa
     8281 gacgagcagg ctactttaga tgttgcaatg gctagcttta agtttaagca taccattgag
     8341 ggtgatagta atatcatgac acaagatgac attgatcatt tactggccaa ggaatcgcat
     8401 gagattcaac gataatgtga taaaggagaa atcgtatgtt atacccaata ctgacaaaaa
     8461 caagaaagat ttatgattta ggggggctct ggcaatttaa gctaggagac cataacccgc
     8521 aggagctcct agcctctgat gagctgatgg ttgtgccgac ctcctttaat gatgtggttg
     8581 tggataagga caagcgcaat tacatcggtg atttttggta cgagcgcttt gttgatgtgc
     8641 cagatcttgc tgctgatgag gagctggtac ttcgctttgg ctctgtcacg cacaatgcaa
     8701 cagtctatgt taatgggcaa gctttagggc aacacaaggg aggcttcact ccatttgagg
     8761 tgttggtgcc tgagacccat tatcaggata atcaaattaa ggtatctgtt tgtgccaata
     8821 atattttaga ttataccagc cttccagtgg gcaattatag tgaagaaact caagaggatg
     8881 gcagtatcaa aaaaattgtc aaggagaatt ttgacttctt caactatgct ggtattcacc
     8941 gtccagtgaa gcttatggtg cggccaaaat gccatatctc agatatcacg atcacgagtg
     9001 acttgtctga ggatatgaca tcagccttag tcgaggtatc tgttgaaacc tcagcagctg
     9061 ttgatgaggt taaggtgacg atctttgatg aagagcacaa gctcgttgcg caggctattg
     9121 atggcaaggc aagacttgat aaggttcgtt tatgggaagt tttagatgct tatctataca
     9181 ctgcccacgt tgagatcatc gtagatggca atgttgtaga tagttatgat gagccatttg
     9241 gtatcagaag tattgcagtt gaaaaaggac aatttttact aaatggcaag cctgtttatt
     9301 tcaagggctt tggtaagcat gaggatacct ttatcaacgg tcgtggattg aatgaagcag
     9361 ctaatttaat ggatatgaat ctgctcaagg agcttggtgc caattcattt cgtacctcac
     9421 actaccctta ctctgaggag atgatgcgtc tggcagatcg tatgggaatc ttggttattg
     9481 atgaggttcc ggcagtaggg ctcttccaaa actttacagc ctccttggat ctttcgccaa
     9541 aggacaatgg cacttggtct gtcatgaaaa ctaaggaagc gcatgagcaa gcaattcgtg
     9601 agctcgtcaa gcgtgacaaa aatcaccctt ctgttgtcat gtgggtcgtg gccaatgagc
     9661 ctgccagcca tgaagaggga gcacacgaat actttgagcc gctgattgct ctttataagg
     9721 cactagatcc gcagcagcgt ccagtaacat tggttaatct gctattagca acacctgatc
     9781 gagataaggt gatggatctg gttgatgtga tctccttaaa ccgttattat gcttggtatg
     9841 ttgatcatgg agacttgatc aaaggagagg ttgggctgcg tcaggagcta ttagaatggc
     9901 agaagaagtt tcctaacaag cctatcctga tgacagagta cggtgcagat acgcttcctg
     9961 gtcttcattc gatgtgggat attccatata cagaggaatt tcagtgccgc ttctatgaga
    10021 tgagtcaccg cgtttttgat gagattccta atctagttgg agagcaggta tggaattttg
    10081 ctgattttga aactaatctg atgatcttcc gtattcaagg caatcataag gggctttttt
    10141 ctagaaatcg ccagcctaag catgttgttg gtttgtttaa agagcgctgg aataccattc
    10201 cccactacaa ttataaaaag aaatagtgta caatagtagc tagcaataag taggaagaag
    10261 ggattgtatg gctaggcctt tagtcgaaaa aacagcagag cgcttgttaa agctaatttt
    10321 agaacgtggg tatgaggttg gagcaaagct ccccaatgaa tatgagttag cacaggactt
    10381 agaggttgga agaagcacta ttagagaagc tgttagaagc ttagcaacta gaaatgtttt
    10441 agaggttaga caaggatcag gtacttatat tagctcgaaa aaaggtgttt ctgaggatcc
    10501 tttaggcttt tccttagtca aggacacagc caagctgacc gctgatttgt ttgaattgcg
    10561 gctattgctt gagcctagga ttgccgcttt gacagcacag catgcaacgc caaaggaggt
    10621 tgaagcctta gagaagcttg ttgttgatat tgaagaggcc gtagctgctg gtgatcctaa
    10681 gcatttgcag ctggatgtga atttccattc cttgatggca aaatacagtg gcaatattgc
    10741 tatggatagc ttgctaccgg tgatcaatca gtcgattcat ctgatcaatg ccaattacac
    10801 aaatcgtcag atgaaagaag attctctaca agcccacaga gatattctga atgcgattaa
    10861 agcgggagat ccgatcgcgg cacatgacgc tatgctcctg cacatcatga cagttaagcg
    10921 aacggctttt ctatcataag cttaagcttg cttgccggaa acagtctatt gagttttgag
    10981 tgatttgctt cttggctcga ataagagggc ttggttttag agatactaga accaagtcct
    11041 ttttttgctt tttccttgac aaatcatctg atgatttata taataaaact aagacaacgg
    11101 tttcatgaaa aggaggagcc tatgctaaac cgattaaaag agaattattt ttttgctatt
    11161 attcgtggaa aaacagtaga agacgctatt gccattgcta agcatgctat tttaggcggt
    11221 attcgtaata tcgagattac ctattctact ccaaatgctt cagaggttat tagaatattg
    11281 tcagctgagt ttgagcatga tgatgctgtg attattggag ctgggacagt gatgacgcct
    11341 gatctggcaa gagaagctat tgcagcaggt gctagctttt tagttagtcc tcatttttct
    11401 agagaaatag cagaggttgc caatcaggca tcaaatcttt atttcccagg ctgtgcaaca
    11461 gctactgaaa ttgtcacagc aatgaatgcc tcttgtccga ttattaaggt ctttcctgga
    11521 ggtgttgtag gaccaggctt tattaaggat attcatggtc ctattcctga ggttgatttg
    11581 atgccatcag gtggtgtgtc gattgacaat gtcaaggagt ggaaaaatgc aggtgctgtt
    11641 gctgttggga ttggttcagc cttagctagc cgagttgagg ctgagggcta tgatagtgta
    11701 acccgtattg cagcgtcatt tgtatcagcc cttgattaag ggaattggtc ataagaggag
    11761 gacgagatgg cttttaatga cgacaatttt atgctaaaaa atgaggcagc aaagcgcctc
    11821 tatcaacaaa tcaaggatca gcctattttt gattaccatt gtcacttaga tccaaaggaa
    11881 atttttgagg acaaggttta tgacaatatt gttgaccttt ggcttggtgg tgatcattac
    11941 aagtggcgct tgatgcgcgc taatggcatt tcggaagaag aaatcacagg ctcagcctct
    12001 aagctggata aattcaaggc ctttgcccgt acacttcagc gctcctatgg caatcctgtt
    12061 taccactggt cagtgatgga gttgaaaaat gtctttggtg tctgtgagct actgactgag
    12121 gataatgcag aggaaatcta tcatcgtatc aatgcttact tggttgagca ccagattagt
    12181 cctagaaagt tgattgcaga tagccgagtg cggtttattg gtacgacaga tcacccgctt
    12241 gatgacctag cttggcataa gaggttagct gctgatgata cctttgagac ggttgtcgcg
    12301 ccaaccttta gaccagatga ggcttttatt gagcatcagc gctttgcaga ttttgtggct
    12361 cgtcttgctc aagctaccgg aagaactatt acagatttta agagctttat agcggctatg
    12421 gaagagcgta ttgcctattt tgcagaaaat ggttgtaagg ccagtgacat cagctttaca
    12481 gagattgtct ttgaagcagc agagccagag caattagacc gtctcatgac aagggtttta
    12541 gagggctatc agccgcagcc gttagaggtc aagcaatggc agacagcggt gtttgcagag
    12601 ctttgcaggc tttataagca ctatggcttt gttactcagg tgcattttgg tgctcttcgc
    12661 aataatcatt cagctatatt caacaagctg ggggcagatg tgggtgttga ctcactggga
    12721 gaccaaacag gactagcaat caatatgaat cgcctgctgg atcatctggt gcaaagagac
    12781 agcctgccaa agatgatttg gtataaccta aatccgagct ataatatcgc ggttgctaat
    12841 acactagcta atttccaagc caatgaaaac ggtattgcgg gctatctgca attcggtgca
    12901 ggctggtggt ttgctgatac caagcttggt atgattagcc agatgaatgc cttggctgag
    12961 caaggtttgt tagctaattt tgtcggcatg ctaacggatt cacgttcatt tttatcctat
    13021 cagcgtcatg attatttcag acgtattttg tcgacctacc ttggtgagtg gattgaagaa
    13081 ggtgaggtac cagaggatta tcaggcactt ggtaaaatgg ctcaggacat tgcctacaat
    13141 aatgctatcc agtattttaa ctaggctgcc ttggtcgtta actagaagaa gcatagaaat
    13201 atgatgttgc tctatgatta aggtcctagt cttaaaagag gctaggacaa tatcggcctg
    13261 ctagctgctg tcggcgtctt gttgattgac tagattacaa aggctagacc aagtagcagg
    13321 cccaggccct ttagttgcaa gggtattagc cccaaaaaca ataataaata acaattgtgt
    13381 gaatcgaaag gaaaaggagt ttacgagaac tcgaggtatg atactatgaa aatgtcgttt
    13441 cgctggtatg gaaagcatga tccagtaagt ttagaggaaa tcaaggccat tcctggtatg
    13501 cagggaattg taacagctgt gtatgatgta ccagttggtc aggcttggcc actagaaaat
    13561 atccttgaat tgaagaggat agttgaggct gcaggccttg agatttcagt catcgaatca
    13621 attcctgttc acgaggacat caagcaagga aagcccaatc gtgatgagct gattgaaaat
    13681 tataagacct ctatcatcaa tgttggtaag gcaggtattc ctgtggtttg ctataatttt
    13741 atgccagtgt ttgattggac tcgctcagat cttaattacc cattgcctga tggatcaacc
    13801 tcacttgctt ttttaaaggc agacttggca gatgtggatc ctgtggcaga tgatttgaac
    13861 ctaccgggtt gggatttttc ttactcaaaa gaagagatga aggctattat tgagcattat
    13921 cgtcatcata tttccgaaga agacctgtgg gctaatttag attattttat taaggctatt
    13981 atgccaacag cagaggcagc tggcgttaag atggctatcc accctgatga tcctccttat
    14041 ggtatttttg gcttaccacg tatcataaca ggtcaaaagg ctgtagagcg cttcttagac
    14101 ctttatgatt cccctaataa tgggattacc atgtgtgtgg gctcctatgc ttctgatcct
    14161 caaaatgatg tgatcgctat gacggagtac gcgcttaagc gccagcgtat taactttatg
    14221 catacgcgta atgtcactgc tggtgattgg ggcttccaag aaaccgctca cttgtcacag
    14281 gctggtgaca ttgatatgaa tgctattatc aaattattgg ttgattatga ctggcaagga
    14341 ccacttcgtc cagatcatgg tcgtcgtatc tggggagatc aaaccaaaac ccctggctat
    14401 gggctgtatg accgggcact tggtgcgacc tattttaatg ggctttatga ggctaatatg
    14461 cgtgcagctg gaaagatacc agattttggc attactgtaa aaacagttgg agataaatag
    14521 aaaaaggggc atgagatgag tcgagttatt gaatttaagg acaaggttgt tgtgatcaca
    14581 ggagctggcg gtgtcctttg tggcagtatg gcaaaggcat ttgcaaaagc aggggctaag
    14641 gtggcactgt tagaccttaa ccaagaggcg gcacaggcct ttgttgatga tattgaggca
    14701 gagggtggta ttgcaaaggc ctatcaggca aatgtattgt ctaaagaaaa cctagaggcc
    14761 gttcgtcagg cagttttagc agattttggt ccagcagata ttttagtgaa tggcgctggc
    14821 ggaaacagcc ctaaggcaac aaccgataat gagtttcacg acacaagcct gccagaggat
    14881 acaaaaacct tctttgacct tgatgaagca ggtatcagct ttgtctttaa tttaaactat
    14941 ttaggcacct tgttgccgac gcaagtcttt gctcaggata tggttggtcg taagggggca
    15001 aatattatta acatttcttc aatgaatgcc tttacgccat taacaaagat cccagcctat
    15061 tctggggcta aggcagccat ttccaacttt acccagtggt tggctgttca tttttctaag
    15121 gttggcattc gttgtaatgc cattgctcct ggatttttgg taaccaatca aaaccgtagc
    15181 ctccttttca cagaggacgg acagccaacg gctcgtgctg aaaaaatcct taagaataca
    15241 ccaatgggac gctttggtga ggcagaagaa ttaattggag gcctcttttt cttggctgat
    15301 gagcagtctg cttcctttgt gaacggcgtt gttctgccaa ttgatggcgg atttgcagct
    15361 tattcaggcg tctaagctaa aaaataaacc acttgagaac tcaaactgca atgcctcaag
    15421 tggtttttct atcgtgacag cttgctttgt agccaagctg ccattaataa aggtatgatg
    15481 atttgtggct tctattgttc cttatcactc tagccttttt tagcaatcaa caagtaatga
    15541 tagcttttaa aaatgaaacg ctgcttgatt aggatttatg attgacagcg ttttcttact
    15601 gtgttagaat taattcatca gatgatttgg aggttggaat gacagctaaa actgaacaat
    15661 ttgtcttttg tgtggactca gatggctgcg caatggacac catgacttat aagcatcagc
    15721 tcttttttgg tccgcttgcg gcggattatt ttgcggtagc agaccaagcg tctttcttaa
    15781 aagagtggga tcgcattaat ctttattcgc gtacacgcgg tgttaaccgc tttgttgggc
    15841 ttgttatggg gctagaatac gcaggagtta cagggattga cgctttaaag caatgggtac
    15901 aacacactgc ctcattatcc aatcagtctc tggaggcgga gcttcttaag cgtcctagtg
    15961 atgacctgca aaaggccttg gactggtcaa atgaggtaaa ccgtcagatt gaggcctaca
    16021 aaggagaggc attggcattt ctaggagctt tagctgctct taaggccttg caccagcttg
    16081 gccaggtttt tgttgtcagc tcagctaata aagaggccgt tcaaaaggaa tggcaggatc
    16141 aaggcctgat gacacatgtt gatggcttgt attgtcagga tcgtggcaaa aaagaggctg
    16201 tcatagcaca gctcattgat gaaggatatg tgagagagcg catgatgatg ataggagatt
    16261 caccaggtga tctagcagct gctgagcaaa accagatcac tttttttcca atcctcgttg
    16321 gtaaggaggc tagctcgtgg caggatctgt cacatgctgc tgaagctttt acaactggtg
    16381 acttgacaga gcttgatgtc aagagcctta cagaagcctt ctggcgtaat cttgataggt
    16441 aggcaggtag ctgaccagtg gagctgagcc tgttagggct tggtagcagg ttgctgtagc
    16501 gccattcatt aaaacagaaa agcaagcaga gaaggcttta gttgaaagga agtacaatga
    16561 cacatttagt agatttaaga aaaaaaccat atagcctaga cgaagaagct atttgctggg
    16621 tggaggatac cattgcagca atgaccttgg aggagaagat aggtcagcta tttgttaata
    16681 tgggggctag tcgatcagag gattatttaa ctcaggtgct tgaggattat catattgcag
    16741 ctgttcgcta caataaaggc atggcttcag aaatttggga tcaaaattat attttacaaa
    16801 ccaaatccaa gattccaatg ctcattgctg ccaatacaga ggctggtggt gatggtgctg
    16861 tcaatgatgg cactaaggtt ggtgatgaaa tcaaggtagc tgcgacaaac gatcctaaat
    16921 acgcttatga aatgggacgg attgcaggac tggaagcgtc agctgttggc tgtaatgcct
    16981 cctttgcgcc aattgttgat ttgacgcgta attggcgtaa tccaatcatt gctaatcgca
    17041 actggggggt aaatgttgat caaatcattg agctttccaa agagtatatg aaggggatta
    17101 tggaatatgg tatcatgccc tttgccaagc acttccctgg tgatggtatt gatgagcgtg
    17161 accatcattt gtcctttgcc tcaaacccaa tgaccaagga ggagtggcta tctagctttg
    17221 gacgtattta tggcgagctt gcagaggctg gcttacctgg tattatggca ggacatattc
    17281 acctgccaaa tgttgaaaag gccatgcacc ctgagcgtga gctagatgat atgcttccag
    17341 cctcacttaa taaaaccctc ttagatgagc tgctgcgtgg tgagcttggc tataatggtg
    17401 ctattgtgac tgacgcttcg catatggttg cgatgacagc ctcaatgcca cgtcgcttat
    17461 tgttaccaac agcgattgag gcaggctgcg atctcttttt attctttaat gacccagatg
    17521 aagacctaca atggatgaaa gagggctatg aggcaggaat tttaagtgac gaacgccttc
    17581 atgacgccct tcgtcgtacg cttggcttga aagcaaagct tggacttcat cgctttgaag
    17641 gacaccgaga agatattatg ctgcctaagg acaaggcgat ggtcttgatt aacacaccag
    17701 aggctcaagc aattgcagat gaggttgccg acaaggccat tacccttgtg aaaaacaagc
    17761 aggcagggat tttcccggta actccagagc gctacaagcg tgtgctgatt gttaacgtgg
    17821 agggctataa gggtggcttt ggtgctatga ttgcaggaca gaagaaacgg gcctcagaca
    17881 ttgtcaagga attgctagag gcgcgtgggc atgaggtaac tgtctgggaa tcaaccgaag
    17941 agcgaatcat gcagctacca gaggaagagc gtgcagcggc tattgctaat gtttatgcac
    18001 aaaagcagcc gatttcaaac attacagagc attatgattt aattcttaat ttggtggacg
    18061 tcaattctgg aggtacagtt cagcgtatta tctggccagc tgctaaggga acaccggatc
    18121 agccattcta cgtccatgag gtcccaacaa tcgttgtttc agttcagcat gcctttgccc
    18181 ttgctgatat gccacaggtt ggtacttata ttaatgccta cgatggcaag gacaacacta
    18241 tgaaggcttt ggttgcaaaa ttagctggtg aatctgaatt cactggagtg tctcctgttg
    18301 atgccttttg tggcttgatt gatacccagc tatggcatag cttctgaggt tgctacagga
    18361 taagtagagg ctttacgtgt tctgcggtga ttgctctgaa tgatttaaaa agatttcagg
    18421 ataaaacctg ttaatcagcc ccttgtagct gcagaaatag ccccataatc cctgtggtgg
    18481 ggagttttat ccgatatgga gatgatagag cctgttaatc ctaaagaaaa gctagagggt
    18541 cattctagct tttctttttg tgcctaatgc tcaaccttgc ttcagatgat agacaagcta
    18601 taagcttgtt gataagtgaa acaattgaac agataatg
//
LOCUS       DARYVE010000042        18490 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYVE010000042 DARYVE010000000
VERSION     DARYVE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18490
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..650)
                     /locus_tag="TVW25_001351"
     CDS             complement(<1..650)
                     /locus_tag="TVW25_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL1378977.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEA"
     gene            complement(746..1711)
                     /locus_tag="TVW25_001352"
     CDS             complement(746..1711)
                     /locus_tag="TVW25_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1378978.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            complement(1704..2480)
                     /locus_tag="TVW25_001353"
     CDS             complement(1704..2480)
                     /locus_tag="TVW25_001353"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1378979.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(2632..3795)
                     /locus_tag="TVW25_001354"
                     /pseudo
     CDS             complement(2632..3795)
                     /locus_tag="TVW25_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3797..5518)
                     /locus_tag="TVW25_001355"
     CDS             complement(3797..5518)
                     /locus_tag="TVW25_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378980.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            5967..7973
                     /locus_tag="TVW25_001356"
     CDS             5967..7973
                     /locus_tag="TVW25_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1378981.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(8164..8574)
                     /locus_tag="TVW25_001357"
     CDS             complement(8164..8574)
                     /locus_tag="TVW25_001357"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1378982.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(8706..10055)
                     /gene="gdhA"
                     /locus_tag="TVW25_001358"
     CDS             complement(8706..10055)
                     /gene="gdhA"
                     /locus_tag="TVW25_001358"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1378983.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(10196..11972)
                     /locus_tag="TVW25_001359"
                     /pseudo
     CDS             complement(10196..11972)
                     /locus_tag="TVW25_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(11972..13717)
                     /locus_tag="TVW25_001360"
     CDS             complement(11972..13717)
                     /locus_tag="TVW25_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1378984.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISIPKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKSYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(13822..15689)
                     /locus_tag="TVW25_001361"
                     /pseudo
     CDS             complement(13822..15689)
                     /locus_tag="TVW25_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(15682..16893)
                     /locus_tag="TVW25_001362"
     CDS             complement(15682..16893)
                     /locus_tag="TVW25_001362"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1378985.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(16993..17841)
                     /locus_tag="TVW25_001363"
     CDS             complement(16993..17841)
                     /locus_tag="TVW25_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1378986.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSASLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(17841..18221)
                     /locus_tag="TVW25_001364"
     CDS             complement(17841..18221)
                     /locus_tag="TVW25_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1378987.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
BASE COUNT         5394 a         4312 c         3276 g         5508 t
ORIGIN      
        1 gcttctgcaa gcatattaag aactatttca agagtggtca tattatccct tagattttcc
       61 tttttcaaac ccttcagatt tttataacct cttgttgtca ttccggacca tgctttggtg
      121 atttcatcag taagaattgc gtattctttg cctttttgta tcccatggtc atcccaagca
      181 tcagtcagtt cttttcttac ctgaatggct tgaagtcttt gatttatcca ctcacgtgta
      241 tatcccttct ttagataagt ttctaaggct ctgtcaatcg taagttcagg atcgataatt
      301 tcatcaattc gttcttttcc aacctcagca agccataact taaaaggttc tgctttaggg
      361 gatgggatgg actggataat acggaatatt ccttgcatat ctgctacatc agttaaacgc
      421 atttttccat ctgttgcttt cattttcaac tgcttacaaa ttgtaagcag ttcatttcct
      481 tcttctttta atctcttttt tagtacagcc caataggtac tagcacctct tacgttttct
      541 tgttctgtca aaactccaac tacatcgact actgaaaaat accactcttc tttttcttcg
      601 tcccaaatgg agcgtatctc tttattttca tacaatttta tttcgtccat tctgacacct
      661 gcctctttta tatcttatcc tgttaaacag gtcttttccc tttttaatac cttatattat
      721 accttaaatt tataattttg tcttttcact gaccaatata ttccttaaag taaatttcca
      781 atgctttttc tataatttct tctacatctt ctttcctttc atcatgaaaa aactttttat
      841 agacactctg agatagtttg atattctgat acttttttac cttcgttttt ttcaagttca
      901 gcaagtatgt tataaccatc tcttgattca gatcttcttg tctgttcatc agatggagtg
      961 ctttggcatc gcttggtttt aaacttagtt ccaattcttc gcacttctga tacagatatt
     1021 cctgtatttc tttggaaaga taggataaat ctactgccat cgtcaaacct attttatctt
     1081 catccacatc ttttttccaa gacttagata attcatttaa tcttaggtac cttgcaatag
     1141 atgcccctga aagattatat tcttttccaa gtgtttttct gctgtctatt ttatcttcct
     1201 ctttactttc cttttctata attccctgat ctaaattgtt tatctccttt tgcaaatcat
     1261 ttctcttgcc ctgacttgct attttttcat atctcatttt aagaacaagg gctttttccg
     1321 tcggcagtaa atcggagaaa gaacgctgta taaggtttgt ttcaattaca taggtatagg
     1381 cttctttatc cgttagattt tctttaacaa tacaaggaat actttttatt tttgtaattc
     1441 ttgctgcatt tactctattg tgtccggaaa gtatttcata gttgttatct tttttcaaga
     1501 cgataattgg attaagaact ccgttttcct taatgctctc taccatatcg tctaatctct
     1561 tacctgtata taaagtaaac ggatgattat gataattttc aagcaaatca agttctatat
     1621 tctgtatatt tccttgttcc aaggcatttc catcatcaag caaaaaatct acggcatcgg
     1681 tgatttctct ctttagaagt tttttactca tagcagatct cctttgccag attgtcatag
     1741 gcaatgtcta cactactgcc ttttgcatat ttttttatgc tttgcccgct atagatggct
     1801 tccccaactt taactgtttt cggaattttg gtttgaaaga ccttgatttt cttttggaac
     1861 atttcttcta cttgctccat cagtgttttg gacagattgg ttctattctc acacatggtt
     1921 agtaaaatcc cctgcacttt cagtttcgga ttcactctct tttttatttt ttgaacagtt
     1981 tttaaaagtt cattgattcc aacaactgcg aacagctgtg tatccgctac tataaggaca
     2041 ctgtctgagg cacaaagagc atttatagtc aaaacactaa gtgatggtga tgtatctatg
     2101 agaatatagt cataattctc ttttaccctc ctaataattt ccgataatat acgttcactt
     2161 cctgtttctg ctctcatttg tgtttcaacg gcggataaga aaatgcttga ggggataata
     2221 tctatctcat cataagattt ggtatagccc tctaccaaat agctttcttc ttcctccagt
     2281 tctaccatta acaaatgccc tatggttttt atattttctg tatttcccat atcaaaacat
     2341 cttgtaagat tagcttgtgg atcaaggtca atgactaata cttttttccc cagttctttt
     2401 agtgaatagg caaggtttag agttgtagtt gtttttccaa ctccgccttt tcgattggct
     2461 atggttatca cttctgccat aaagtccctc cttcttctct atacagagat ttcattttat
     2521 gctatacttt tatataattt tagatataaa aaaagatgat agcctcaatc catcatcaag
     2581 tttaaaagtt ttgcggaagc ctttaaccat tgattttact tggatttatt gtactatcat
     2641 cattatagca ttgtccccag agccagtatg ccctactagg gcaaccgtct cccctttatc
     2701 agcatgaatg gtaatatcag ataaaactgt cttgccattt tcgtaagcaa aatacacctt
     2761 ggtaaaatcc acagtaccat ctgttagctc aattgctcgt gctttatccg gctctgtctg
     2821 cgcctcaagc agcttcatta ggcgcgttcc tgtcgctgtt gagcgctgaa tattaggtag
     2881 ctgcctaacc agcatactta ataaatcaaa caagcgcagc aaataattga cgtaaataaa
     2941 gagcttacca actgtgatgc ctgatctccc ctgcaagaac tggtaaccaa taacagccaa
     3001 aatagcggca atcatgccat actttaccaa ttccgtcagg gtccatgaag caactgactc
     3061 tgcaaaaata atcctatcat cagctgtttt catctggtgg atctgctctt caaattcctc
     3121 taagatcgta tcctcttgat gataaagctg aataatagaa acaccattca tggtttcgtt
     3181 gacttgtgtg ttgacagcgc tcctagcctg ataaaaatcc ttcattggct ggtcagtcaa
     3241 gcttttatac agccattgca tgccataaaa gagtggcata ataagcagca acagcaagcc
     3301 tgacttcaca tcaaggtaaa tcatcaccac ataaataaaa ataatttgtg aaagactgac
     3361 aataatttga gacaaaaggt tatcataaaa ttgattcttc agggtttcag tatcattaac
     3421 aatcctagtt gcaatctttc ctgcaggctg atgatcaaaa taagctatcg gcagcctctg
     3481 catgacatca aaggctcgat tacgaagatt agcaacgatc ctattagagg aataaaccag
     3541 cattcgataa gagatataac gcaaaactgc tgttatcaca attaacagca aatacagcag
     3601 gagcaagcgc tgaaagcctt caatcggtac ctcttttcct ctagctatcg gagtcaagta
     3661 atgatcaatc gtttgttgca acaataaggg agccatctga cctccagctg ttgccactag
     3721 caaaaagcct attgccaggg aaaaagccaa ggtcacagct ttaatttctt ttattaattt
     3781 tataaatagg gtcatcttaa acctcctgag cctgctgacg ctggtactgt tcataatacc
     3841 agcccttctg agctaaaagt tgttggggct gaccttcctc tactatctgc ccctgatcca
     3901 gaacaataac ccaatcggca tgctgaatcg cagacaagcg atggctaaca ataagtgttg
     3961 tctttccctt tctttcgtct tgaatgtgtc gaataatatc agtctctgtt ctagcatcaa
     4021 ctgccgacag ggaatcatct aaaatcagca aatctggctg ggacaaaaag gctctggcaa
     4081 tcgaaatacg ctgcttttga cctcctgaaa tagacagacc acgctctcca atctcagtat
     4141 ccaagccctt tgccattcct tgaacatcac gcgtaaaggc cgcagtttca atcgcctcca
     4201 agatttcctc agttgtagct gcctttttcc ccatcgcaat gttttgagca accgtttttg
     4261 aaaacaggat atgctcctgt ggcacatagc caatttgacg ctcaagtgat tgacgcttat
     4321 aatccaagac actacgatga ttaatcatca gctgcccctg cccaagaggg tattgtctca
     4381 aaaactgcct gacaagggtt gttttaccag agcctgtttt accaacaatc cctaaggttt
     4441 gtcccttttt cagggttaaa ttgatctttt ctaagctagg cctagaacta ttggcatagg
     4501 taaagctata gtctataaaa gcaatctgat caaagctctc taactcaagc tggccatcag
     4561 gctccatatc atcacttgtt tcgatgagtt cattaatctt accaaaagag gtctttcctg
     4621 tctgataaac caaaataaag tctgacagca tgccaaaggg ctccaccaaa gacaccagat
     4681 aaagctgcag cgcaatgact tgaccaagtg ttacctctga gcttgctatg agctgtaggc
     4741 ctaccattaa aatgattact gtactaatgg caatcatgac gctgtaaaga ggaaagtaca
     4801 aggcacgata cttggccacc tgattccatt tatctgccaa attctgagtc ttttgagcaa
     4861 aatgaagtgc caaataatct tttttactgt aagcacgcat cactctaatg ccctcaacgg
     4921 tttctagtac ctcatcacta aggcttgaaa tcgcctcacg cgcctcttca accaaatgct
     4981 cttgcttttt cgtcacacca tagatcatca ccatcataag caaaatcggt actattccta
     5041 tcaaggtcat tttccaagaa atcaaaaaca tggtcggaat aataaaagca atcataccac
     5101 cagcatatag gataatcatc aagccatagc cgataaggtc cataagtgct tcgacatctg
     5161 ttgaaaaacg cgtgatcatg tcacctgagc gaaatttctc ataaaaaggc gttctcataa
     5221 aaacaagctt tcgaaaggca cgctgctgaa tatcaaactt aaaatgaact gcctcctgaa
     5281 ataaatgaag atgccacaaa taagcaaccc cataagacac tactgccgta gccaaaagaa
     5341 tgataacatg cctcaccaat gcccctgagc ttagctgatg ccttgacatc aaatcaacca
     5401 agtcttgaat aacccttgtt ggtatcacaa gtgaggcatc atatatcact aaagtcattg
     5461 caataaggat ataaatccat ttcttttgct taatatgttg aacaattaag gtcagcatca
     5521 tatcctccat ttctgaacta acctatttca agctgtctta aaataggatt tttgcacaca
     5581 aaaagcccgc aataagatat ccttcctacc gcgggctcta ctatttctat ttagtgaaac
     5641 taaaagaaac taactgtttt ggttagaaag gagactatcg taataatggt taaatagttg
     5701 aatgaaacgg atcattatta atttctcctt tcttttaatc tgcctaacat cttatcatag
     5761 aatactgggc ttgtaaagcc ttttttggat agttcttcta tttttttaca aaaaacgctt
     5821 ccaatgtttg cattttaaac gttttcagtg attagcaaac gctatcgttg aatttttgtt
     5881 agctttttta ttaatttttg ttgaattctc atttaaataa tagtacactt aacttgtgac
     5941 aatactttaa acttttagga gcgtttatga aaaagcattt tgttttaaaa agtagtgttc
     6001 ttggtgtctt tgccggagtt tctatgctag taaccggcgt gcaggccgat caggtagacg
     6061 tgcaatttct tggtgtcaat gactttcatg gtgccttaga cacaaccggc tctgcctaca
     6121 tgccagaagg aaaggtatct aacgctggta ccgcagcaca attagctgct tatctggacg
     6181 atgcagaggc tgactttaag caaacaagcc cagatgggac aagcattcgt gttcaaccag
     6241 gagatatggt cggagctagt cctgctaatt ctggactatt acaggacgag ccaacggtta
     6301 aggtattcaa ccagatgggc tttgaatacg gaacccttgg gaatcacgaa ttcgatgagg
     6361 gcttagctga attcaaccgt atcatgacag gcactgcacc tgctgaagac tcagctatca
     6421 acgacattac taagcaatac gagcatgaag cttcaaatca aacccttgtc attgcaaatg
     6481 tcgttgacaa ggagaccaac acgattcctt ttggctggaa gccttatgct gtcaaagaag
     6541 tcccagttaa tgataagtca gtcaaggtgg gctttatcgg tgttgtgaca acagaaattc
     6601 caaaccttgt cctaaaacaa aattatgaac aatatgatta cctagactct gcagaaacca
     6661 tcgttaaata tgctaaagag ctccaagagc agcaggtcaa tgcgattgtt gtcctagctc
     6721 atatcccagc aacaagtgat aacggggtag ttcatgatga gatggcagca gttatggaaa
     6781 aggttaacca gctttatcct gagcatagtg tggatattgt ctttgctggt cacaaccacc
     6841 aatacaccaa cggtaccatt ggcacaacac gtgtcgttca ggctgtttca caggggaaag
     6901 cctatgcaga tgttcgtgga acactagaca ctgacctcaa tgattttgta gccactcctg
     6961 aagcaaaggt cattgccgtt gctcctggca taaaaacagg caatgccgac attcaagcca
     7021 ttgttgatca agccaatgac attgtcaaaa ccgttaccga gctaaagatc ggtacagcag
     7081 ctacctcttc aacgatttct aaaacagaaa acgaagacaa ggaatctcct gttggcaatt
     7141 tgataacaac tgcccaatta accattggta gaaaaacctt ccctcatgtt gattttgcca
     7201 tgacaaataa tggcggtatt cgcgctgact tggtggtcaa agaggatcaa accattacct
     7261 ggggagctgc acaggctgtt caaccatttg gcaatattct tcaggtcgtt caaatgactg
     7321 gccaacaaat ctatgatgtc ttgaaccaac aatacgatga agaccaaaaa tacttccttc
     7381 aaatgtctgg actcaaatac acttatacag ctaatgaggc taacgatcct tcaacaccgt
     7441 ttaaggtagt aaaggcttat aaagataatg gtgaagaaat tgatccagca gctcaataca
     7501 ccctaatcat caacgacttc ctatatggcg gtggtgatgg cttctccgtc tttaaggacg
     7561 ctaagctact aggagccatt aatcctgata ctgaggtctt tatcgaatac atcaaggacc
     7621 ttgaagcagc tggaaagact gtaagtgctg gtattaacgg tgtgaaaacc tatgtcactg
     7681 ccagtcttga aggctctact caaagtgatc ataccggcaa gcacgagatc atcaaccgcg
     7741 tctttaagaa tcgtgagggc aaggtgcttg ctactgagct tgtctctgac ctatttacgc
     7801 ctgctcaaaa tgctaatcct gccacaagca tcaagcctct agcagctaaa aagcaagcta
     7861 atgctgcctt accagcaaca ggaacaagcc agcattctgc tgctgccatg acaatcctag
     7921 gactactaac cttaactggt actagccttt tcaagaaaaa ggaaggccaa taaaatcgtc
     7981 ctagccataa cagcaataac cgactgtatc ttaagcatac agccggtttt ctgatttatg
     8041 tgacgtttat ttgtttcgca cctgttgagc aagacaaata aaccacccat ctatggactg
     8101 ccctcattcg ttagattttc tgtctaactt ttggggtgca gttcactaac gggtggtcat
     8161 gatttaaatc aatatgccct ccagatgatc cagctcatgc tggcagattt gtgcaggcag
     8221 gcctgtcaat ctcagggatt tcttgtgcca atgtgcatca aggtaatcaa ccttgatctc
     8281 ctgataacgc tttgtcttac gttggccgat tagtgatagg caggattcct ctgcctcaaa
     8341 cgcttcacgc ttagcaatta atacaggatt aaacatcacc aaatccacaa agcccatgct
     8401 aataataata accctcttgt tttcccctat catattagca gccagcccca ggcagctatc
     8461 acgataataa gctaaggtat cctgcaggtc ttgaccaatc caaaggtcct ttttcgttgc
     8521 tggctgtgct ttttgctgca agaaaaaggt gtccttcacg atttttttga tcatcagctt
     8581 ctccttgatt cattgctcta atcggcatgc attgtctaga tgaccgatcg tatatcttaa
     8641 cgtcattgag ctaagattaa tgtgctaacc ctactgatat attcagcata taccagccac
     8701 agctcttaaa cgattccctg tgctgacatg gcctgagcaa ctttgagaaa gcctgcaata
     8761 ttagctccca ccactaggtt gccttcttga ccacattcct tggcggcagc ggctgctttt
     8821 tgataaatag ccttcatgat gtcatacaat cgatgatcca cctcttcaaa ggtccatgcg
     8881 gtacgtccgc tattttgtgc catttccagc gcagaaactg ctacaccgcc agcatttgct
     8941 gctttagcag gtccaaaaag aaccccagcc tgctgaaatt gctcaatagc ctctaaggtt
     9001 gagggcatgt tagccccttc gacaacagct ttaaccccat gctcaatcaa ggctttagca
     9061 tctgcctctt gtagctcatt ttgagtcgca catggaaagg caaggtctgc cttaatagtc
     9121 cagatggatc cctcaccagc cggtgtaaac acagcagccg ggtgactctc tagataggtc
     9181 ttgatacgct cacgcttcac ttccttgatt tgctttaggg tctcaagatc aatgccctta
     9241 tcatcataaa cgtaaccaga ggaatccgac actgctaata ccttaacacc taaggcctgc
     9301 aatttttccg ttgcgtaaat ggcaacattt cctgatccag atacaatagc tgttttacca
     9361 gccaagtcct gccccttagc cgccagcatt tgctgagcaa aataaaccac accatagcct
     9421 gtggcctctg tgcgagccaa agagccacca taagctaagc cttttcctgt caacacacca
     9481 ttcttaaagc cattaagacg cttatattgc ccaaataaat agccaatttc gcgagcccct
     9541 acaccaatat caccagcagg aacatcaagg tcaggtccaa tatgcctttg cagctctgtc
     9601 ataaagcttt gtgtgaagcg catgatttct aggtctgatt tgcctttagg atcaaaattt
     9661 gatcctcctt ttcctcctcc aataggctga ccagtcagag catttttgaa aatctgctca
     9721 aagccaagaa atttaactat agactggtta acagaagggt gaaagcgaag ccctccctta
     9781 tatggaccga tagctgatga aaattgcacg cggtagccac gattaacttg gaccctgccc
     9841 tggtcatcaa cccaaggcac cctaaaggaa atcacacgct caggctcaac caagcgctct
     9901 aatagatttt cctcaatata attagggtat ttttcaaaaa caggaatcaa ggaatcaaat
     9961 acctccttga ccgcctgaag aaattcagtc tcatgcggat tatccctttt gaccttatca
    10021 aaaacactgg ctacatagtc ttttgctgat accattatat atcctctcgc ttcttcattc
    10081 tattttaagt atagtcaata ttataaattt tctgaatttt gatgtcaagc ttttactatg
    10141 atctaaagca aattaaaaga gccttggaac gattcattcc aagaccctaa gctttttaag
    10201 actgactggt cttaaattgg ctatgataaa gctcataata gaagccctta gcagctaata
    10261 ggctgtcatg attcccctgc tcgataatct gaccatcttt tagaactaaa atcttatccg
    10321 cctcttgaat ggttgataag cggtgagcaa taacaaagct agtcctgcca accattaatc
    10381 gcttcatcgc cttttgaatc aaaagctcta aacgtgtatc aacagacgag gtggcctcat
    10441 ctaggattag cagctttgga tctgctaaga gagctcgagc aatggtcagc agctgctttt
    10501 gccccaggga aatattgcta gattcctgat tcatcaccat atgatagcca cctggcaatg
    10561 tcctaatgaa atgatcaaca ttggcagcct tagcagcctc aattatttgt tcatcagtcg
    10621 cctctaaatg accaaagcgc aagttttcct gaatgctgcc ctcaaagagc caagcgtcct
    10681 gcagcaccat accaaactga cgcctatagg cttgacgtga caactgacga atgtcctgac
    10741 catcaactgt gatagagccc tcattcacat cataaaaccg cattaataaa ttaatcaggg
    10801 tggtcttgcc ggctcctgtc ggaccaacga tagctaccat ctcaccaggc ttaacctcta
    10861 aattgaaatt tctaatcaga ggattgtctg ctgtatagct aaaatcaacc tgattaaagg
    10921 acacctgacc tgttaaatca tgttctaaat gctcttgggc aatagtcaat tcatctgcct
    10981 catcaagcac tgcaaagata cgttctaagg atgacttggc actttgcagt ggaccagcca
    11041 gctgtgttat ggtctgaata ggctgactga tttgccaaat gtactgaaca aaggcttgca
    11101 tgtttgttcc cgattgtcag gcggcctgct atcacctgta agccagcgat taaggcaaca
    11161 atcatgtaaa cagaatctga aataaaatgc agaactggca tcatgatccc agaaataaag
    11221 ctggccttaa agcctacttc ttgtaatcgc tcagtgatct ggtgaaattc ctcctttgag
    11281 gcttcttcac gaccatacag ttttaaaata ttaaagccgg tcaaattttc ctgcacaaag
    11341 ccattcattt ctcccaaaat attagcctgc gctttaaaat aaggctgtga tttttttaaa
    11401 acaaatcgag aagcagcata tatcaacggg atagcgataa tcacaacaga ggctaggggg
    11461 gcattaatat acaagaccat gccaaccacc aaaataaggg taaaaaaggc gttaacaatc
    11521 tgtaaaaagg actgctgtaa ggcattagag actgtctcaa catcagaggt aaaccggcct
    11581 agcatatcgc cgaactgatg cttatcaaaa taagacacag ggatacgatt aattttttga
    11641 ctgaggtctc gacgaagatc acaaatgctt gattgcacag cccttgtcat aaaatagttt
    11701 gaaccataag agcctaactc gtaaacaagg gccctaatga tatagagagc taaaagaaag
    11761 gcgatatagg ttttattaat gcctgcacca gagactccct ttgctatgtc taataggttt
    11821 gcagatagct ctgttatcac caagccaaga acaaagggct ctaagacact catcacagca
    11881 ctgactattt ttaaaataat ggcagttatt agtgagagcc tataggcact aaggtaggtc
    11941 caaattcttc taaacacatg cttttcagtc attaatcccc ctcctctttt gtcatgtctt
    12001 ccttgtttag ctgagaattg gcaatttcac gatagatggc attgcttgta agcaattcct
    12061 catgtgtacc tcggccaaca atttctccct gatccaagac aatgatttga tcagcatcca
    12121 taatcgtgcc caccctttga gccacaatta agaccgttgc atcttgtgtc acctctttca
    12181 gccgtctgcg taattcagca tctgtcttgt aatctagggc agaaaaggaa tcgtcaaaga
    12241 tatagatgtc tggctgcttg accactgctc tggcaataga caggcgctgc ttttgccctc
    12301 ctgatagatt actgccggcc tcagctagat gggtttgata gctcttttca cgactggtaa
    12361 taaagtcctt cgcttgggaa acctctgttg cctgctcaag ctcactgtgg ctggcatctg
    12421 acttaccata ttttaggttt tcctcaatgg ttcctgtaaa tagcagggct ttttgaggaa
    12481 taaagccgat tttagaacgc agcgctttta attgataatc cctgacatca atgccatcaa
    12541 ccaagattct ccctaaggtc acgtcataaa atcgtgggat cagattaacc aaagatgatt
    12601 ttcctgaacc tgtcgagccg ataaaagcaa tggtctctcc aggcctagtc ttaaatgaga
    12661 tgttatgtaa aactggactt tccgtttcac ccggataggc aaaggtcacg ttatcaaatt
    12721 ctagataacc acgtgttgtg aacgctgtta taccatcttc atttttagga atcgaaatcg
    12781 gcatatccag cacttccttg atacgcttgc ttgacactgc tgttttaggg tacatggtaa
    12841 agaggttggc aaacattaaa aatgaaaaaa gagcatgaaa gctatattcg ataaaggcca
    12901 ccaaatcacc aatcttaaac tgcccccttg ccaagggatc caaggcaaac cagacgatcc
    12961 ccacaatcat agcaatgata atttgcacaa ataagggctc tgttaagcct gtcaaggtaa
    13021 atagtcgctt tgagattcca gaatagtgat cattgcgctt attgaagcgc tcttcttgaa
    13081 agtcttctct tgcaaaggct cgaataactc tcagacctgt caggttttca cgcaccaatt
    13141 ggttaatacg atcaaggctc tcctgctgct tttctgataa gggtcttgtc tttatcgcaa
    13201 cataaagcac cacaataact aaaaaaggca tggcaacagc cacaatccaa gccaatgatg
    13261 gactggttaa aaagatcatc accactgaaa agatcatcat caaaggagtt acgacaccca
    13321 gcctcaagga catttcagca aattgcatca aaacaaaggc atcatttgtt atccgagtaa
    13381 ccagggaggc tatgccaatt ttttcatatt ccgaatgcga ataatcctgc aagcagctat
    13441 acatgtcatt acgtaaatcc ttgatcatgt tggtggttag cttacccgaa gcataggata
    13501 aaatcacccg tccaatgaca cctaaaagta cgataataaa catcatcaga gcccaaaaat
    13561 aaagagccct ttgatcctgc tgcataacgc cttgatcaat catacgagcc aatattgttg
    13621 gtagccccag attgaccaga acaaataaca agccacccac aatatcgaaa caaatccatt
    13681 taggtcttgt ttttaaatag gaccaaatta aagccattca tttcctccca aataatagtg
    13741 atatgaaaag aagcgcaagc tagcacttct ttttgtctat aactagttta acacaaaaat
    13801 atgaaattga cacataatta attattcttc taattcgctt aggtaatcaa agcgctcata
    13861 ggcttcaagc agctcaagat tccgctgatc cagctccttt tgatattgtg ccaattggtc
    13921 gtaatcactt gccgctctga gcatttgctc ctcaatagta gctatttgtt gctcgatagc
    13981 agctagcttt tcttcaatag ctgcccattc ctttttctca agataggaca ttctcttttt
    14041 agaggtgacc tgatggtcag tgccagcttt ttgctcactg acagcaggct ctatgacctc
    14101 tgcttcaaaa gccttttcat ctaaatagtc gctatagtta ccatagtatt ctctgatagc
    14161 tccatgctca aaagccaata cttttgttgc aaccttatcc aagaaatacc gatcatgact
    14221 cactgtaatg accggaccag caaattgagc taaaaaatgc tccaacactg tcaaggttgc
    14281 aatatccaaa tcattggtcg gctcatccag cagcaggacg ttgggctttt cgatcaagag
    14341 ctttagcaaa tacagtcttt tttctccccg cctgatagct tagcgattaa ggagccatga
    14401 ctagaacgcg gaaaaagaaa ttgctccaaa agctcactga tgctagtggt gccaacactg
    14461 gtcttgacct catctgccac ctcctgcaaa tagctaatca cgcgcttgct gccgtccata
    14521 tccttgattt gctgtgaaaa ataaccaata cggatcgtct cgccaatctc tagctgacca
    14581 gctgttggtt ttaagtcacc agtcatcaag ctaagcaggg tggtctttcc agcaccgtta
    14641 gctccaacaa tgccgatacg gtccttattt tgaatgatca ggttaaaatg ctcaataatg
    14701 gcctgatcac cataagcaaa ggaaacctcc ttgaaattaa tgaccttctt gccaatacga
    14761 ctggcttcaa aggccatatc taattgatct ataggccttt cctgatgaag gtcctttttt
    14821 aactgttcaa agcggttaat tctggcctgc tgcttggtcg cacgcgcctg tggctgtgtc
    14881 ctcatccaag ccagctcctg tttatagagc tgctttttct tatgcaaatg agctgcttcg
    14941 cgctcgtctt gctcagcctt cagacgcaca taatcctggt aattgccctg atattcagtc
    15001 acatgagcct tatccaattc aaagatacgt gtggctatac tatccaaaaa atagcgatca
    15061 tgtgtaataa atagaacagt ccttttagag gtccttaagt aatgacttaa ccaagcgatg
    15121 gtatcaatat ccaaatgatt ggtcggctca tctagcagca acaaatcact ggctccaagc
    15181 aagacctgag ccagctgtac ccgacgtctc ataccaccgg acaggtcacc cactctctga
    15241 tccagattga caataccaag ctttgataag accgtcttaa cctcactttc gatcgaccaa
    15301 acatctaatc gatccatctc agtcatcacc tctgctagct tttcctgatt gctatctgaa
    15361 tagtcagcca tcaacagctc atattggcga atcagctgca tttcctttaa ttctagggac
    15421 agaacagtat ctaaaacaga ctgatcatca tcaaagtccg gctcctgtgt taaataagat
    15481 atacgatagt catttgcctt tgaaaaaggt gagcggtcac catcaaagcc cactttttca
    15541 gaaataacat caagcaaggt tgtttttcct gtcccattga caccaataat gccaatgcga
    15601 tcaccagcat gaataataaa ggaaatatcc tgaaaaacgg tcttatctcc aacagacttc
    15661 gtcagatgtt caacgataaa atcactcatt tagtagttcc cttctaacaa aagcctcaat
    15721 gtgttctctt tgattgacga gacgcccctc tacaatggcc tgctcaatct gatttaaaag
    15781 cattcccagc tgtggtcctg gcttcattcc aagctcacga atcagataag agccattgac
    15841 cacaatatca tgcttatcat ggatcgtcag ctcctgatac aagctctcaa cacgcttggc
    15901 ctcactgacc aagccctgtg cctgtcgtaa atcgtcaacg agtaaagcca agtccttgcc
    15961 aaacgagtaa atatcccatt tttctagctg tctttcttgg cgaatctgat aaagagaggc
    16021 catcatcgta accctacgct gaaaatcatt agaggttttc caagccttta aaaaggcttt
    16081 aggctgatca agctccagca taaccagcaa ataggcccaa gcctgatgat tgtcctgaaa
    16141 cacataatcc gctgctaagg ttttcaggta cttttgcagg gcttcttcct tgcccactaa
    16201 gcctggcaaa tagttaaagg cctgacatgc caccatagct aagatacctt tacgccattt
    16261 tggggccatt aaaagcttat caagctcaat aaaagagcgc tcaatagaaa tcttctccag
    16321 caagggagca tggcttttca ttgcttcaaa ggtctcagcc tcaatatcaa aatctaagct
    16381 ggcagcaaac cgaaagcctc gcataatccg cagggcatcc tcctcaaagc gctcctgagg
    16441 ccttccaaca gctcttagaa gcttatgctt taggtcctct aagccattaa agatatcaat
    16501 aacctgtccg tcctcatcta aggcaagagc attgacagta aaatcccttc gttttaaatc
    16561 ctcttccaag gaccgaacaa aggatacctg actagggcgc ctataatcca cataaacgtc
    16621 ctcagttcga aacgttgtga tctcatattc actgccattt tctaaaacaa gcactgtgcc
    16681 atgctcaatc ccaacatcaa ttgttcttaa gaaaatagcc tttgtctcct ctggatagca
    16741 gctagcagct atatcaacat catgaatagg cctgtttaat aagctatccc tcacacttcc
    16801 accaacaaaa taggcctcaa agccagcctg cttgattttt ttcactattg gtaaagcctt
    16861 ctgaaattca gaaggcattg tcattaatgt tatcatgttt taatctacca cctaaaagct
    16921 cctagagcct tgtcatatgc ttcccgttaa aggctgtcat atcaagctca gattggtcat
    16981 gggcaagcct ctttagacaa gaggcgttat gccaaaggca acagctcctt ctccaagatg
    17041 ggctgcaatc actgcaccaa aatgaacctc ctcaacaggg caggtatagc cattatccaa
    17101 caagagctgc tttaagatat cagccttatc ctgcgctcta gcatggataa ttgatacctc
    17161 gtactgacca ctagctgtca attcctttaa gatatcaacc aagcgcttca tggccttttt
    17221 ttccgttcta accttttcat agacgacaat ctttccttca ctatcaaagc gaagaattgg
    17281 cttgatgctg agcaaatttc ccagcaaagc agaaccgttt gataagcgtc ctcccttgac
    17341 caaatgattc aaatcatcaa ccatgataaa ggctgtggtt ccagcgattt gctcttctag
    17401 cttatccata atctctgcaa agctcaagcc ttgctgagac cactctaaag catttctaac
    17461 catgctgcct aatgatgctg aggtgatttt actatctgga aaagcaatgg tcaactcagg
    17521 gtgctcctcg atgagaaatt gaatattttg ccaaaatcct gaaataccac tagccaagaa
    17581 caagccaatc acatgagtat agtgctcagt tgacagacgc cctagtaaat catctaattc
    17641 agagaggctg ggctgactgg tttttggcag ctcttgagat tctctcatgc tttggtaaaa
    17701 ggcttcaatg gtcaggtttt gtccttcgac atagctttga ccatctatga ttacaggtat
    17761 gtctaataca aaaatatcgg catgctccgc taactgctct ggaaggtgag ctgtattatc
    17821 agttattatt gctaacttca ttaactttta aactccaaat taataccagg acgatccaag
    17881 gcaatttctg tcacttcgta ggtcaagcgc ttcaccatgt ctaataatgg agcagccaag
    17941 gattcgacct cctcttgtgt aaattcacta ggcttatcca ccaagcgtcc taaaatacga
    18001 accatctgtg aaatcacacc actaatcaca aactcttcct tgacaatgac aaattgtaaa
    18061 acagaaacaa tagccgtctc tttattttcc acatctttat taatcaactg aaaggttact
    18121 tcaaagtttg tttccggtgt tccattttct ttttcccatt ctaaatttct ggcgtcataa
    18181 tggtactgat tgacaaattc tttttcacgt actaattgca tgatttcgtt ctccttaatg
    18241 gcgatatgac ccattatagc atagatttga cgaatattaa agtagactta aaccagtatt
    18301 ttggataatt tttttccaga ccttgtcact tcaataaata taaacctgcc ttctatcaac
    18361 caatcaatct cctacaacaa aaaaacaccc caaggtgtac tgcccccaaa aagttgaacg
    18421 aataattatt gaaaggattt agttctgtat tgaacagggc taagtccttt tagtttagtt
    18481 ttgattcgtt
//
LOCUS       DARYVE010000043        18070 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYVE010000043 DARYVE010000000
VERSION     DARYVE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18070
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            182..409
                     /locus_tag="TVW25_001365"
     CDS             182..409
                     /locus_tag="TVW25_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378988.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            413..835
                     /locus_tag="TVW25_001366"
     CDS             413..835
                     /locus_tag="TVW25_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1378989.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            1003..1233
                     /locus_tag="TVW25_001367"
     CDS             1003..1233
                     /locus_tag="TVW25_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378990.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            1610..2044
                     /locus_tag="TVW25_001368"
     CDS             1610..2044
                     /locus_tag="TVW25_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1378991.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            2582..2656
                     /locus_tag="TVW25_001369"
     tRNA            2582..2656
                     /locus_tag="TVW25_001369"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            2815..3306
                     /locus_tag="TVW25_001370"
     CDS             2815..3306
                     /locus_tag="TVW25_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1378992.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            3341..4594
                     /locus_tag="TVW25_001371"
     CDS             3341..4594
                     /locus_tag="TVW25_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1378993.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            4604..6103
                     /locus_tag="TVW25_001372"
     CDS             4604..6103
                     /locus_tag="TVW25_001372"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1378994.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            6103..7713
                     /locus_tag="TVW25_001373"
     CDS             6103..7713
                     /locus_tag="TVW25_001373"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378995.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            7679..7900
                     /locus_tag="TVW25_001374"
     CDS             7679..7900
                     /locus_tag="TVW25_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378996.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            7952..8236
                     /locus_tag="TVW25_001375"
     CDS             7952..8236
                     /locus_tag="TVW25_001375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378997.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            8322..8561
                     /locus_tag="TVW25_001376"
     CDS             8322..8561
                     /locus_tag="TVW25_001376"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378998.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            8546..9148
                     /locus_tag="TVW25_001377"
     CDS             8546..9148
                     /locus_tag="TVW25_001377"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1378999.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            9150..10022
                     /locus_tag="TVW25_001378"
     CDS             9150..10022
                     /locus_tag="TVW25_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379000.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            10033..10281
                     /locus_tag="TVW25_001379"
     CDS             10033..10281
                     /locus_tag="TVW25_001379"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379001.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            10284..10670
                     /locus_tag="TVW25_001380"
     CDS             10284..10670
                     /locus_tag="TVW25_001380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379002.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            10664..11008
                     /locus_tag="TVW25_001381"
     CDS             10664..11008
                     /locus_tag="TVW25_001381"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379003.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            11005..11358
                     /locus_tag="TVW25_001382"
     CDS             11005..11358
                     /locus_tag="TVW25_001382"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379004.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            11361..11729
                     /locus_tag="TVW25_001383"
     CDS             11361..11729
                     /locus_tag="TVW25_001383"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379005.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            11733..12230
                     /locus_tag="TVW25_001384"
     CDS             11733..12230
                     /locus_tag="TVW25_001384"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379006.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            12250..12657
                     /locus_tag="TVW25_001385"
     CDS             12250..12657
                     /locus_tag="TVW25_001385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379007.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            12671..13282
                     /locus_tag="TVW25_001386"
     CDS             12671..13282
                     /locus_tag="TVW25_001386"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379008.1"
                     /translation="MTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVNDYA
                     KIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMHFE
                     KDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPNKD
                     EASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            13283..15730
                     /locus_tag="TVW25_001387"
     CDS             13283..15730
                     /locus_tag="TVW25_001387"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1379009.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            15734..16495
                     /locus_tag="TVW25_001388"
     CDS             15734..16495
                     /locus_tag="TVW25_001388"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1379010.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            16506..>18070
                     /locus_tag="TVW25_001389"
     CDS             16506..>18070
                     /locus_tag="TVW25_001389"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1379011.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDP"
BASE COUNT         5894 a         3143 c         4123 g         4910 t
ORIGIN      
        1 acccacgcag ttactgataa aaatttattt acagagtata catttgcgac gcagcaagat
       61 gccgagaatt atatcagaga cttagagcta aacggatcta agtgtgccct ttgagtatta
      121 tgagaggaga tttgcaaaat gatagacacc gatacacttg cagcagtacg ggaggctgat
      181 catgactaaa aacgactttt taacaggttt tgtacttata cttttagctg cttgcatttt
      241 tgcagcagga tttgtgattg gatctgactg tagtagcgag cactacgagc aacaaatgac
      301 aggcttgcgt atgcagcttg ttaacacgca gcagcagctt aagcgtgcga gtgaggatag
      361 agcaaggcgg actaaaagga ttgcggatct gaccgggaat ggaggatagg gtatgatcga
      421 cgaaatcgaa ctcgacctac aaaaaccaga aatcccacag tttgtcgctg actacataga
      481 tgatatgcac aaaaacgcac gtacattgag atacgctttt aaatacatgg aaagtaacat
      541 aaaaatgcac aaatggtgtg tttttgaaag gcaagaaacg tttgttaatg cttttttata
      601 cggctacaca ataaaaaaag aaaagctgta tattgttgag atccctaatc ctaatagtgg
      661 catagaacac aaacatattg cactagcaag gttagcgaat ggaaaacttg gattttcaga
      721 gatcatagat actgattttt attcaagaga agatgtccga ctcaccgagt cagaaatccg
      781 caaagatttt gattgggcat ggagagaggg gtttgctaaa gaggtgacgg aatgagcaga
      841 gataaaacca gaatcaggaa cattgtgaag tccatgaaac agttaggtgc tagcgaagaa
      901 gagacagacg aatacatgta tctatgcgtg tttaaaaagc ctcacgtcat agctcaaatc
      961 cgtaaaaagg ctaagatttt cagaggcgaa gggtggtaac agatggcata tttacgagaa
     1021 gaaagagaaa cagttattca ttacgacgaa ttggatgact gctggacttt tgaaactaac
     1081 gtccgtaggc atattacgaa aatagaaaaa cgcatcgaac tgtacgagat tctctcagag
     1141 gaattcgatg accgaggaag gcgtatctat atctgtgcga aaatgaagac aggaactgtc
     1201 agtccctttg cgaaaccacc aagaaggaaa tagctataga atcgatttta agcttcaaaa
     1261 acatggcaag aacgcacttc tgggaacgtg aaacacctag ctaatataaa tgtaccctag
     1321 aacaatttaa atcgaaaaaa tgattagcta cataggtttt aatcggctta tgtggcatag
     1381 accgaaatta aacacagaag gatgtgatga caatctcctt acacccaaaa aatctaacgc
     1441 tggttatcgg tcaccagcta ttatccaagg cgctaatact gacatcgtgt gcctgagctg
     1501 gcttataaaa aacgaaagag agggcttttc tccacacaaa aagacgtcca tgcgaacgcc
     1561 tccttggtta tatctgttaa caccattata ccacactgag ggggctttca tgacgttttt
     1621 tcctgagatt gatatccaaa aaacaaaatc caatgccaag cgtaaattga aagagtatcc
     1681 acgctggcgg cggatagcta acgatgtaga tactcaaaaa gttacagcta cttactcatt
     1741 tgagccaagg caacctcatg gagtccatag caagcctgta gagaggttag cacttaatcg
     1801 tgtgtcagcg gagcaggagt tagatgcgat tgagcaagct gtcagcatga tactagagcc
     1861 agagaggcgc aggattttgt acgataaata cttatcacct tataaaaaag cggacaaggt
     1921 tatttataca gaattgtgta tgtcagagag cttttattat gatacgctcg atatcgcttt
     1981 attagctttt gcagagctat atagagaggg gtctctgatt gtcgagcaag gagtttttag
     2041 ctagttttta tacagtaata taatagtttt tgtacaaaat agcgtgttaa tatagtatca
     2101 tagcaaaata acaaaaagag ataaccattt taccaattga ctatttattt agtcgccaac
     2161 tttaactacg atcaaacttg ttattttgaa ggtacatggg acgtgcaggt tcgaatcctg
     2221 ccgtctcaat accagctatt tccaaaatgg aaacagttgg aaaagacaaa ccccccattc
     2281 ctttaaaggc agatacgttc tgatatgggg ctttttatga ttaactgcaa gtaaaacaag
     2341 ggtcgcaacc ttgcttgtgg ttagtagacc tagtggtcgt ttatgcacgt tcgattcgtg
     2401 caaggtctgt tgggttgatt gcaataatcc ttttgtggac gcacaacaaa aatgtgatgt
     2461 aagtcacggc taaggtttgg gcggcgatag aatagatgcg caactatcgt tgggtcacgt
     2521 ctcagagttt gcatagttaa tattaaccga tgggcacacc ctgcgtcagt gggttgttta
     2581 tggatagctt agcaaagggg ttaatgcgac caactgttta gtttggtagg cgtgagttcg
     2641 aatctcacac tattctttca ggaacatgaa ccgtgattgg aaaacggtag aggtagcgcc
     2701 ttgataattg gattgtcgac ggtctgatta tatgtgtcgg ttcaattccg actgttcctg
     2761 ttctagtcac caattgtggt ggctttttat tatgtcacga ggaggtgatg gaaaattgct
     2821 aagttaacta taaaacaaca aaaatttatt gatgagtaca tcatctgtgg aaatgcgaca
     2881 gaagccgctc ttaaggcggg ttatagcaaa aaaacggctg ggcaaatcgg tgagcagaac
     2941 ttgaaaaaac ttgaaataaa atctgccatc aacgaacggc taaaacaact cgaaagcagt
     3001 aaaatagcta gtgcaatcga gatcctacaa gttcttactg ccgttcttcg gcaggatttg
     3061 acggaggagg ttgttaccct taatcctgta acaggtgagt acgttactat gcagaaaaaa
     3121 cctagcatcg cagaagtcat aaaagctgct ggtgagttat tgaaacgtta tcctatccaa
     3181 gaacaaattg aaaaaatcaa gcaagaaaac gagttgttac gccttaaaat tgaaaccgtc
     3241 aaaggcgcca agcctgatac ccatttgatg gaaaaactgc tggaggtaat cgaagatggc
     3301 ggttaggata aaaaagttat ccacaaaaca aaaagacatc attagacgcc cttttaacta
     3361 cgaattagag gtcaatgagg gaacacccag aagtggaaag accaccgctg ggcattttcg
     3421 ttatgctagg tatctgattg agtcagaaga tgaaaatcat cttgtgactg cttataatca
     3481 agaacaagct tatcgtttgt ttattgatgg agacggtaca gggctgatgc acatctttga
     3541 cgggaactgc gaaatcaaac atgatgagcg aggagatcac ctgcttgtaa caacaccaaa
     3601 aggtaataaa agggtttatt acaagggtgg aggtaaagtt aactcagtcg gtgctattac
     3661 aggtatgtct ctaggctcag tggtcttttg tgagattaat ctactgcata tggattttat
     3721 ccaggagtgt tttaggcgta cctgggcggc taaactgcgt tatcacttag cagaccttaa
     3781 ccctcctgcg ccacagcacc ctgttattaa agacgttttt gacgtccaaa ataccagatg
     3841 gacgcattgg accatggacg ataatccaat attaactgcg gagcgcaagc aaaacattat
     3901 caatagcctc aaaaaaaatc cttatcttta taaacgagat gtactcgggc agcgggtgat
     3961 gcctcaaggt gttatttatg gtctttttga catggaaaaa aatgttctag acactttgat
     4021 tggcgagcca gtggagatgt atttctgtgc agatggtggg caatctgatg ccacatctat
     4081 gtcttgcaac atcgtaacaa gagttagaga taatggcaag ataagtttta ggcttaatcg
     4141 gacagcgcac tactatcata gtggagcaga tactggtcag gtcaaagcca tgtcaacata
     4201 cgccagagaa cttaaggctt tcattgactg gtgtgttaaa aaataccaac ttcggtactc
     4261 tgatgtcttt attgaccctg cgtgtaaggc tttgcgcgag gaattacatg ccattggtat
     4321 tctgacgact ggagcgccga acaacgctca cgacgtaaac agtaaggcga aaggtatcga
     4381 agttgggata gaacgtggcc agactttgat ttcagacggt gatttttatc tagtaaatca
     4441 caaagaggaa aaatatgatc attatcattt cctgaaggaa ttagggcttt atagccgcga
     4501 tgataaaggc aaaccaatag acgcaaacaa ccactcaatg gacgaattta ggtactcggt
     4561 caatgttttt gtgggacgat acaaaatgaa ataggaggta gtcatgttta gaaacctctg
     4621 gactaaaata aaaggggtga tgcaaaaaat gggattgata aaaggtttga aagatttgaa
     4681 cctgcaccgc gaaattgaac tgtctgataa gcattatgat agtatccaaa tttggaaaga
     4741 gttgtatcaa ggctatcacg ataaaataca cgattactat gagaaatcta tcttagatgg
     4801 tcgtaaaaag aagaagcgtt tgactttgaa tatgcctaaa gttgtgacct cagagcttgc
     4861 tacattgatt tttaatgaaa aatgtgaaat taacattggt tctgaaaatg agagtttgac
     4921 aaagctcatc actgaaacgt tagagaaaaa taattttact caggagtttc aacgcttctt
     4981 agaatatagt ttcgccttgg gaggtatggc aatcaaagca tatctcaaaa aggacggtac
     5041 tatcggtctt aattttgtac aagcggatag ttttattccc atttcgtggg ataatgctgg
     5101 gattagcgaa gccgtatttg ttgatacgca gcatcgtgga aaatacaagt acacgcattt
     5161 ggagtggcat acttgggaaa gtgagttgta tgtagttgct cacgagttat ttagaactga
     5221 caagtcaaat gatgatgttg gcattcgcgt accgataaca gagatttatc cagatttaaa
     5281 atcacaagta gtcatcgaaa aactatcaag accgctattt gtttacctca aacctaattc
     5341 ggcaaacaac attgatctat caagtccgct agggatttca atctatcaca attcgtttga
     5401 taccttgcga gcgattgata ttgcctacga tagctttgag cgtgagtttc gacttggccg
     5461 taagaggata ttggttccag cgactgccat tcgtactgta gtggatagcg aggggaattt
     5521 ccaccgctat tttgacgcaa cagacgaaac atatgaggct ttccacacag gtgaagacag
     5581 caaaattcaa gatatcaaag atattagtgt tgaattgcga gttgatgaac atattgcagc
     5641 tattaacgca ctgttgaact tacttagtat gcagattggc tttagcccag gttctttcag
     5701 tttcgatgga gtatcgggtg tcaagacagc caccgaggtt atctctgaga attctaagac
     5761 attccgcacg aagcaatctc atgaaacgat ggtagaagca acattgaaaa atcttgttgc
     5821 gattatcgtt gattttgggg atctttatgg tttgatcgag ggtgagagta agtataatgt
     5881 aactgtaacg tttgacgact ctattgcgca ggacagaacc caggacgctc agtattatat
     5941 agggttggtc gcagctgggt taatcagcaa gaaaaaagct atgatgaagc tgtttaatct
     6001 gtcagaagaa gatgcagagt tggaaatcca aactatccac gaggaaagcc ggacaacaaa
     6061 cgatatgtca attgatttat ttggtttgga cggtgatgct tagtggatta tgatactcat
     6121 atccagctgt cttttgactt aatagagctt tattctgatg tcgaacgtga attgttgacg
     6181 tcaataggtc gcaggtttgc aaaacactat gacgaaatgg tagctggcga catcatggat
     6241 tggcaaatta ggcaattact cgaagttgga gagctgagaa aagagcacat cgaaatcatg
     6301 cgaaaaagtg cacgcgtgag tcgtgagcgt atgattgaga tgctgacgga ggcaggttat
     6361 acctccgcag gaaggtatga ggattttttt aaagaggcat acgttaaagg tttaatcaag
     6421 ctcaatccat ctgctgcaga caacagcatg aggttgttgc gagtgttaaa tacttacatc
     6481 aatcaagctg aggacacact taatcttgtc aatacgacca tgttacagtc tggccaagat
     6541 acttttttag atacagtcaa tcaagttgtt gcttatgttt ctacaggtat caagacccca
     6601 caagttgcta tgcgtgacgc tctaaaaaat gctggtcaaa agggccttac agtctttcgt
     6661 gctaaaaatg gcgcccagtg gtcaacggag acttatctca atatgatcac tcggacgatg
     6721 aactctaaca tttctaacgc tatggaagat gagcgtaggc atgagtatgg tgttgattac
     6781 atcgaggtat ctagccatgc tggcgcacgt ccaaggtgtg ctccttatca aggtcggata
     6841 tattacgatg gtgtcggaga tgatccgcta gagaaatacc cgcacttctc agagacttct
     6901 tatggcgaag ctgctggatt gtttggcgtt aattgcggtc atcataaata tccttacgtc
     6961 ccaggtatga gtaaacagac ctttttccct tacagtaaaa gcgaaaacga taaaacctat
     7021 gcagagtcgc aggtacaacg taaattagaa cgggaagtta agcagctgaa acgggaacga
     7081 gcaattctaa ctgctgcgaa ggacaaagag ggggctaaat tagcttctca acgcttggag
     7141 aacaagtggc aggaattgcg tcagtttact gctcaaacag gcagaacgag acgatacgac
     7201 cgcgagaaat cgctaaatac tattttgtct gaggacaaga aaaaagccat tgtcaaagat
     7261 aatttgaaaa tcagagatga gtatcgagcg attaagaaag ctatccctga agtagctcct
     7321 aaaaatcttg aaacctatta tgatatgcgt tataatggtg gcaagatata cgaggattta
     7381 gttagggatt acaaagacta tataagatgg tctaaagctg aatttcctac taaaaaatct
     7441 tttgaagggc atattgatag tcacttaaaa gagtttccag gattgactgg taaacaatat
     7501 cagaaaaagg ctgctgactt attatctaga ccgataactg ataatatttt aggttatgat
     7561 acagattcta gacgtgttag gtatgactta gaaaataaca tttttgcttt agggcgcgtt
     7621 aaacaaggta cgattacgac tatgctgaaa ccaaaggaag gggttgatta ctttgacaat
     7681 gactggaaaa gagagtttga taatcttaaa tgatttagaa tatgtccatt gtcctgtttg
     7741 tggaactttg accgaggttt atgatatttg cgatacttgt aaatggcaga ataccggtga
     7801 gacaaatatt gatggcggtc ctaattatat tacacttgag gaagcacgac gaaggtgggc
     7861 aaatggtgaa cctttgcgca acttttttaa agaccaataa tacaagcact gtaacagtgc
     7921 tttttttgta ctcaaaaaag gagagagtaa aatgaacaaa cgaattgaaa agaagcgtcg
     7981 cacacaaatg atgttagaca gaatcttgcg cattgtagaa ttgatgtcgc aagcaactga
     8041 cgacaacttt gctatcttgg aaaagcgctt agaaaaagct gaaaaacgta acgaagagct
     8101 tatggaaatc atcttagtaa acgttaaaga ggtaaataac cgctttgacg agctagaaat
     8161 ctgccagaag attgttgaag atgatgtcgc agagctcaaa aaagctaaga aaaaaggctg
     8221 gttcagccgg aaataactta atcgtgtcga attcgatgcg gttttatttt gccctgccgc
     8281 atggcgataa actaggtaaa aataaaagaa agaggtctaa aatggctgtt attatcgtac
     8341 aaacacgagg cggagatatt gaagttccca ccccattacc agcaatgcaa gctaataaag
     8401 cgattcaaag tcaattattc gataaggagc tgactttttt atgcgtggat aatcatgctt
     8461 ttgctaaaac tgaggtttta cacgttttgg tcgaaacaga agaagatgaa gaattaccac
     8521 agtcaaaaca taaggaggaa gaaacatgct acatggatta aaacaccgtt tgtttaaact
     8581 agccccagat actggagcag gcggaggcgc tgaagttact agcgagacta acgctgaagc
     8641 tggacgagtt gagcaaacag tatcgcaaca acaagctgat ccggttgata ctgaggcaat
     8701 caaaaatcaa gcaattaatg aggttctaag tcaactaggt gtttcttcgg tagaagatgc
     8761 caaagcaaat ctagcttctt ggaatgaata tcaagaaggt cagaaaacag agtttcaaaa
     8821 aattcaagat agtttgactg tggctaataa ctctttggct gagcgcgaca ctatgattgc
     8881 tagcttacaa gctcagttag ctgctgctca aatgggagtg cctgcggaaa acacctccga
     8941 tgttatcact ttggccaata gtttggtcca cgataaaaca gacatcaatg cagcgattac
     9001 taccgtactt gagaaatatc ctcatttcaa aggaggtgat gccgatgtag ctgataaacc
     9061 taactttgtg actcaaactc agagtcaaac ggaaacgacg gaagacgctt tttttaaagc
     9121 gttaggacta acaattaagg aggactaata tgtcaatcaa ttatattact aaacatgaag
     9181 gaatattcga aaagaaacta atgcaaggcg ctttgacgtc taacttagag acaccaaaag
     9241 tcaactggtt aggtgcaaag tcttttgagc taccaaccat ctcggtgact ggctataagg
     9301 cgcacacacg ctcaaaaggg tataacgcag gtactgtatc taacgataaa aatacttata
     9361 cgctcggctt tgatcgtgac gtagagtttt ttgtggataa ggcagacgtc gatgagacta
     9421 accaagagct gtctatggct aacatctcaa acacttttat cacagagcat gcaacgccag
     9481 aagttgacgc ttatcgcttt tcgaagattg ccacaaatgc gatcgataat agccatttta
     9541 agcaggaaga tgactactct actactaatg tttatgagcg cttaaaagct gctattttgc
     9601 ctattcgcaa gtacggagct ggcaatatca ttatctatgt ctccagtgag attatggact
     9661 ttttggagcg ctcaaaggac tttacacgct caatcgcgac aacatcaccg caagggattg
     9721 atactcgtgt gacatctctt gacggagtgc agctcataga ggtttgggac gatgcccgct
     9781 ttaagactaa atttgatttt acgacaggct ttgtcaaaga tggcagcggt aaagacatta
     9841 actttttgat tgtggccaag cctgcggtta ttgcaaaagc taaatttaac tctatttatc
     9901 tttttgcacc aggtcagcac accgaagggg acgggtatct atatcaaaat cgcttgtatc
     9961 acgacctttt tgtgcttaaa tctaaacaag atggggttta tgtatcccat aaatcagctt
    10021 aggaggttaa cgatgaaaac atacgagaag gacaatcaag tctataaagt acaagaaggc
    10081 agcgagctgg aaattcagct gattgccgac ggctttaaag aaattattga agcaaacgaa
    10141 aaggaaactg atatcactaa aatgaagctt gataagctaa aggcttatgc tgaaaatgaa
    10201 ggcattataa ttcctgaaga tattaagaaa aaagaagatg ttttagcttt tattaaggaa
    10261 cagcagcaga gaggtgagta gtgatgctca cctttgattt ttacaataag ggatattgtg
    10321 gctcacagct gaatgaagaa aagttcgggg agctgtcaaa acgtgctgag cgtaaaattt
    10381 tggcacttat tggcttgaaa aaggagcaag tgaagaattt gccacttgat attttagagg
    10441 cggtaaaaat ggctgtctgc gcccaaattg agtatcttaa cgcaataggc gttgaaagtg
    10501 ctatcggagt aacctctgta acccaagcta aagtcggcaa ttttagttac acagacggaa
    10561 agaaagcgac tgtatcagct agtgttggct ctgttggtgt tagccctgac gtgctagact
    10621 atctgcttcc gagtggattg ttatacaagg gggtgaatac gagatggtaa aagaagtcaa
    10681 acctatccct aaagagttat tagttgacac agttacttat ctagcagttg gcaacaaaga
    10741 cagctgggga gcagaaacgg tagtatctac agaattgtca caggtgttag tacaacctag
    10801 aagcagtatc caacgtgggc aacaaaacga gagtaatagc tacgagttgt tactcttttt
    10861 tgattgtgta aactcgttac cagtagatca tcagtttaag gttgacgaca aaattagtta
    10921 tctaggaaaa gagtatcgta tcgcaagtgt tgaggtacta aaagcttttg accagtcgcc
    10981 acatcactat gaggtgatgc tagaatgata ggttttaagg ttgaagtcat ctttaacgct
    11041 agtaaattga ttgccaagag tgaagcatct gcaaagacag ctcgctttgc tttaagtggt
    11101 caaatcaaaa aggatagtga caagtatatt cctgctcgtg agtggaatct gcgagatagc
    11161 ggaagagtaa ctgaacgctc agtatcttgg catacaccgt acgctagacg actctactac
    11221 aatcctcagt ataactttag caaggataag aatccgaatg cacaaggcaa gtggtttgag
    11281 gttgctaaag caaatcatgc agagcattgg tatgagctaa caaagaaagc ctatggtgct
    11341 gagtttagag gagattaatc atgacattta ttgatttttt gctcagaaaa gttcaagaag
    11401 tgagcggagc ggaaccggtc cttggcatta tggggaatag tgataaggtt gctattatcc
    11461 ctatggctgg aaattttgac aatcgagctc ttgacgaaag taagattagg atttttactt
    11521 tccaagtttt ggccaagagt aaaaaacagc aggaagcttt tttgacaaca gaaaacttgg
    11581 tcaatggtct agacggtcta tcaaatgagc cgtttactgg aggatatctc attaagctgg
    11641 agtgtacgac gaccactaac tttgttgaaa aagatagtga caaaaattat ttatatacag
    11701 ctcttttcag agcagaatta ggaggataag aaatggcagc agataagcca actttttatt
    11761 tacaatccga gcataagctc gaaatttcag aagatggaaa aacttggatg cgactagcag
    11821 gtggtatcag tgaattagaa ccagacggaa atgaagaagt atcacaagat gcttatcttg
    11881 acggctctga atctgatgtt acaggaggtc agctagtact agccttaact ggacatcgtc
    11941 tagtaggaga taaagctcaa gactggatct atgcacgtca attccgatat gggggcaaac
    12001 gtcgtggttt tacgcgttgg acattgccag gaggaaaaac acagtttacc tttgcctcta
    12061 cgtttgcaaa tatcaaaggt ccatcaggag cggctaacgg taaaggtgaa attgaatttg
    12121 aaatccattc gaacgaaaca cttgtaccta ataaagtagt tgtagaagtc actaagacaa
    12181 acaaagaact tgcgtctgaa gcacttggtt tagaacgtca agagcgataa gtagaaagga
    12241 tagtcagcaa tggtgagaca gtttgaattt aagaaaacgg ttgaagaaat tgagattgca
    12301 ggggaaatct acttactgcc tcttgatgat gataacctct tacgtatcca acgtgacttt
    12361 attagttacg gaaaagagat cgaagaactc caaaaagttg aggtagaaaa aggagatcca
    12421 gacgatctgg cggataatca taagcaacag cttttagtaa tgaaaaaggt catcgagtca
    12481 ccatttggag aagggagttt tgagaaactt tacgaagcat cagggcactc tttaatgaat
    12541 atggttgact tattggatta tcttgttgag ttagtcgctg aaaaagttga gcaaaataag
    12601 gctcgtgcca ctaaagcaaa agagaagtat tactcctcga agcgcaagaa aaagtaggta
    12661 gcttatgaag ttgacagaaa catatgaagt tcttgctgat gcttttgaat ttggcggtca
    12721 tatcgtaact gttgacttgg cttttgatgt cgtgttgcga gtcatggagc ttcttgccga
    12781 cgcagaagtc aatgactacg ctaaaattgt ctggactttg gatatgctct tgccatattt
    12841 tgatcgtacg gagttaagtt ttgatgaaga atttgaaatt ttcgaatata tcctaaagac
    12901 gtttatctat gaacaagaag acggagaaga tgacagttta ggaggaatgt cacaaacgaa
    12961 aacaatgcat tttgaaaagg atgcagagtt aatctttgcg tccttttttc aaagttatca
    13021 tcttgaccta tttgaacaac agggaaaatt gcactggcga aaatttatgt cactgctcat
    13081 gaatctgcat aaagacactc cttttaagga agttgtcagc tatcgtgtca tgaaagtgcc
    13141 taataaagat gaagcatcgg aagagtatat caaacacgtc aagaagatga agcgtatcta
    13201 ttcgctagaa gacgaatctg agcatcaagc gctaaatgat gacaagcttt cagcgttagc
    13261 agcaaggttt ggaggtgagt agatggcaga tggtagtgtt attattgata ccctgctaaa
    13321 gactgagaaa tttaaccaag gtgtagggaa actacaaggt aaattagctg gattaggatc
    13381 aaagttgacc agcattggta ccggtctaac tctaggctta actgctccta ttgtaggaat
    13441 cggagcggca tcgctcagca cgtttactac atttgaaagt caaatgaatc gtgttaaggc
    13501 gatttctgga gcaacagcaa gtgagttcag aaaactagaa gaccaggcta tcaaacttgg
    13561 agcttcctct gtttttagtg cgacagaagt agcacaagct caagaaatga tggcttctgc
    13621 aggttttaaa gtcgtcgata tcttaaaagc aatgccgggt gttatgtctc tagctgctgt
    13681 atctggtggg gatatggcat tagcaagcga ggcagccgca acagctgtca atatgtttgg
    13741 acttgaagct aaagacgcag cccatgttgc agatgttttt gcacaagctg ctgcggatac
    13801 taacgcagaa gttggagata tggcagaagc cctaaaatac gccggacctg ttgctggggc
    13861 tttagggatt agcttggaag aaaccgcggc agcaattggt atcatgtcta atgcaggcat
    13921 taaagggtca caagcaggaa caactttgag gacaagcctt tcacgactta cggatccaac
    13981 taaaaagatg cgaggaatca tgtccgaatt aggacttgaa tttttcgatg ttaatggaaa
    14041 aatgaagtcc ttatctggta ttaccaaaga acttcaaacc aaaatgggtg atttaactga
    14101 tagtcaaaag agtgcagcta tctctacttt gtttggtaaa gaagcaatgt ctggaatgct
    14161 tgccctagtt aattctgctc ctggcgcatt agacaagcaa acacaagcac ttatcaattc
    14221 aaatggtgct gctaaagaaa tggcagacac catgaatagt ggtgtcaagg gatcgattga
    14281 ggagcttaaa ggttcgcttg agactgctgg aatctccata ggtaaaatat tggcgccagc
    14341 cctaacgtcg gttatcgggg cgataacaag ccttgtgaat tggttcaata acctaagtcc
    14401 gacaatgcaa aacgtggtag ttgtactcgg aagtttactt gctgccattg gaccggttgt
    14461 ccttattata ggggttgtta ctactcagat agcagctttc cagcaaggcg tcggactagt
    14521 ctttaatgct gtcaaaggat tacaagctgc ttttgccttt ttgacgagtc ctatagggtt
    14581 agtcatcgta gccataggtg cactaattgc cgtatttgtt tatttgtgga atacaaacga
    14641 acaatttaga acgaagatca ttgagatttg gacggctatt tcgaactttt tacagcccat
    14701 catacaattt attggtaatt tcataaggga aacgtggact caattagcta ctttttggaa
    14761 cgaaaatcaa gcaactatta tgacaatagc ccagacaact tggtcattta tccagacgat
    14821 atttacaaca gcaattgaaa tgataaaatt ggccgttagt gtttttttag ggttattgca
    14881 atcaacgtgg tctgtaactt ttaattctct taaggttatc gcacaggtcg catgggcttt
    14941 tatttccaat gttttcaagg gaagtttagg gtccatactt gcggttgcat ctgctatatt
    15001 tgagcaaatt aaatcaacga ttgatcttgc gatgaaaatt attcaaaata tcatcaaaat
    15061 catactatcc gcgatagaag gtgattggga cggtgtatta gaaggtatca aaggaattgt
    15121 ttccgcattt ggagatttta ttcaatcaac tttctcaaat atgatggata ctgctaaacg
    15181 cttagtcgga gctggaatag ataccgtaaa aggaattttc gattctttgt ggaatattga
    15241 cttgttcgga gccggtcaag cgattattaa tggattctta aatggtttgc ggtctatgtg
    15301 gggagctgtc acagatttcg ttggcggtat tgcaagctgg attgcagcaa acaaaggtcc
    15361 catctcatat gatagggtac tattgaagcc gcatggaaaa gctattatgg acggactcgg
    15421 taatagcatg aaaactaact ttaaggacat tcagaaagat gtttctggca tggctgacga
    15481 tttaacaaga agttttcaaa tcaaaaggtt caacggtttt ttgccagaaa agtatactac
    15541 taagcttgat gagcttaaaa aatatgcgca agccacgctt ggcggaatga ttttagcccc
    15601 taacatggca gttcaaccga cagtcgttgt taacatcagc aatgaagcag atagcgatat
    15661 catcaggcaa aaagtcaatg ctaagaatgc acaagatgct attattaatc agttattcaa
    15721 gaaagggtaa aacatgttca gtatagagtt tttagacgga gagcgactaa gcgccgatga
    15781 acgaggatgg aaagttaaag agatgtcctc atcaggactt gaacaaaacg tcgttagcga
    15841 gtctcctaaa atgcgttctg gtcgccttgt ttatggtctt tatcatggca tcaaaactta
    15901 tcaacttgtt tttacaaaaa tcattaaaga tacccttgat tatagccgtt tagtagatga
    15961 agttaattac tattttttac gtgatgaacc atactatctt taccgcgact ttagaaagaa
    16021 agctgatcgg gtggacttgc cgaagaagcg ggcgaaggtg tttactaagt caatcgacca
    16081 tcaaaaaaat gggcttaaag ttgaatttac agctaagctg gaatcttatg aactacccta
    16141 cgaagaagat actgaggttc agcgggtcac ttggacggca acacattcat ggcacaataa
    16201 gggagggcat cgccttgacc ctcgttattg cccaatgaag atgaccataa cagtatcagg
    16261 ttcaggagct gaacttaagg tgctatttaa cggtcagcct tatttttggt ataaaaaatc
    16321 agttaaacaa ggggatatct ttatcattga tgggacggac gttgaaaaaa atagatacaa
    16381 ttgttttgaa gattgccata agcaaacctc ttttttaaaa acaggaaata acagaataga
    16441 tattcaagga gcttcgtgtg aagctctttt tgaatataga ctactgtatt tgtaggaggg
    16501 ttagtatgca ggtaaaaaca aagcaaggtg ttttttatgt taacgcagac tacaccgtcg
    16561 tcgaaaaaca aggtgactat cctaagctaa cttgtactat tcctattaag ggaaatgaga
    16621 cttggatagc agattgccaa gaacttgacc gcttataccc agctggggaa caagatgaat
    16681 ttattattat caatcctatt aaagtcacta aggggagttc gtatgatttg gaaattacag
    16741 cgataggagc ctttcatttt gaatttgtaa aggctcgtct atatgaagaa ctaccagaac
    16801 gaatgtatac tttagattac ttgctcgatc tcctgtttaa agacagccga ttcagttata
    16861 agctacaagg tgattattct actagaaggt tcagtggctt cggagatgat aacaaactga
    16921 ctttattcca tcatttaatg gaacgatttc aaacagaatt taaagttgtt ggcaaggtcg
    16981 ttttagttaa cacaaaagta ggtaaagata caggatttca gttccgctat cttagaaata
    17041 tcaaggatac aaagtactcg gtagacgtaa ctaacctgat gacatacgtt aaaggatatg
    17101 gagcctggtt tgatgaaaat gaccattcaa agggaagatt aattgttgat tatgagagcc
    17161 ccttatccaa agagtatggc aaacttgatg gtaagcccgt tgttgatgaa cgaatgagtt
    17221 taaaagaaag tcttatcaaa aaatgtaagc tagccgtaga tcgctctgta tctgtcagct
    17281 taacaacgac tttagtctct ttaaaacaac aggattatca aggtgcggcg agaataggag
    17341 actctatttg gtttattgac gaacgtatat ctattgaaaa aaagattcgg ttcagcgtag
    17401 taacaactta ctacaatgca tatgatgata ttttaaagca ggacgttact ttaggtgata
    17461 aagataccta ctctcgatat caaagtttag aaaactcttc tcaaacagag acaaatgatt
    17521 ttcaaaaagc gatgagtagc aaacttgcag aagttcaaga tgatgttaaa aagacgcata
    17581 ttttagtatc tggcactact aggattttct tttctacaga gtttcctcag gataatccta
    17641 agggaactat aaaagaagat gacattttgt accgtaatca cgatgggaca acattgatgt
    17701 acaggtggaa tggtgttcaa tgggaattag tcccgttggt aaacgatcca gatcgttggc
    17761 gtgaggaact ggagaaacaa atctctgagg ctgtcgaaaa gctcaaacaa gagcaaaaag
    17821 taatcaacca gagaaccgat aaagagctcg aagagtttag agatacgctc aaaaacctat
    17881 ctttaccaga ggaagccatt aaaaaaatca cagaggctat caaagttgat gatatcccgt
    17941 cgattaaaca gtcatttgat gacttaaaaa ataaagtcag cgagacaagc gagaccgcac
    18001 gattaaacgc tgagattatc gggacagatg gcaagacccg ctacaacaaa aatttgctag
    18061 tcggcgaccc
//
LOCUS       DARYVE010000044        17631 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYVE010000044 DARYVE010000000
VERSION     DARYVE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17631
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            21..632
                     /locus_tag="TVW25_001390"
     CDS             21..632
                     /locus_tag="TVW25_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1379012.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(693..1328)
                     /locus_tag="TVW25_001391"
     CDS             complement(693..1328)
                     /locus_tag="TVW25_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1379013.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(1362..2234)
                     /gene="sdaAA"
                     /locus_tag="TVW25_001392"
     CDS             complement(1362..2234)
                     /gene="sdaAA"
                     /locus_tag="TVW25_001392"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1379014.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            complement(2246..2917)
                     /gene="sdaAB"
                     /locus_tag="TVW25_001393"
     CDS             complement(2246..2917)
                     /gene="sdaAB"
                     /locus_tag="TVW25_001393"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1379015.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            3198..4322
                     /gene="mnmA"
                     /locus_tag="TVW25_001394"
     CDS             3198..4322
                     /gene="mnmA"
                     /locus_tag="TVW25_001394"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1379016.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            4527..4991
                     /locus_tag="TVW25_001395"
     CDS             4527..4991
                     /locus_tag="TVW25_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1379017.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            4994..6892
                     /gene="mnmG"
                     /locus_tag="TVW25_001396"
     CDS             4994..6892
                     /gene="mnmG"
                     /locus_tag="TVW25_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1379018.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            6980..8956
                     /locus_tag="TVW25_001397"
     CDS             6980..8956
                     /locus_tag="TVW25_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1379019.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            8953..9405
                     /gene="rplI"
                     /locus_tag="TVW25_001398"
     CDS             8953..9405
                     /gene="rplI"
                     /locus_tag="TVW25_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1379020.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            9426..10802
                     /gene="dnaB"
                     /locus_tag="TVW25_001399"
     CDS             9426..10802
                     /gene="dnaB"
                     /locus_tag="TVW25_001399"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1379021.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            10819..11091
                     /locus_tag="TVW25_001400"
     CDS             10819..11091
                     /locus_tag="TVW25_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1379022.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            11615..12226
                     /gene="rpsD"
                     /locus_tag="TVW25_001401"
     CDS             11615..12226
                     /gene="rpsD"
                     /locus_tag="TVW25_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1379023.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(12433..12966)
                     /locus_tag="TVW25_001402"
     CDS             complement(12433..12966)
                     /locus_tag="TVW25_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1379024.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            13098..15380
                     /locus_tag="TVW25_001403"
     CDS             13098..15380
                     /locus_tag="TVW25_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1379025.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            complement(15484..16539)
                     /locus_tag="TVW25_001404"
     CDS             complement(15484..16539)
                     /locus_tag="TVW25_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1379026.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(16558..16983)
                     /locus_tag="TVW25_001405"
     CDS             complement(16558..16983)
                     /locus_tag="TVW25_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379027.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            complement(16970..17296)
                     /locus_tag="TVW25_001406"
     CDS             complement(16970..17296)
                     /locus_tag="TVW25_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1379028.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            17498..>17631
                     /locus_tag="TVW25_001407"
     CDS             17498..>17631
                     /locus_tag="TVW25_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1379029.1"
                     /translation="MKSIIEHYQARPLGEERCYAVCLPLIWQEGRWQVLYEIRSQHIS
                     "
BASE COUNT         5124 a         3198 c         3904 g         5405 t
ORIGIN      
        1 aaaagtgagg tatttattta atgtttaaac aagacatttt gaaacaacgt tattttagtt
       61 ttggcattgt agcagctgct attgctttgc tcgcagtagt ttttgctttt tcaagtgaaa
      121 atgtaaacac tgattcctat gctaaagctt ctgatactaa ggttgtgaag aaacatcata
      181 aaacaaaaaa atcaacagta gcaaaggctg caaccaagga gcagccagct gagcaggcag
      241 agccttcctc tgctgatgca gcaccagctc aggaatcagt agcttctgag gtagctagtc
      301 ctgctgtgca agaggctgct cctcaagctc agtatgcagc tacaccagtg gcttatagca
      361 atggagtaat cctttctaac ggcaataccg caggggctat cggtagtgaa gcagcagctc
      421 aaatggcggc agctactggt gttccacaag ctacttggga agccattatc gctcgtgagt
      481 caaatggaaa ccctaacgca gctaatcctt caggtgcttc aggattattc caaaccatgc
      541 caggctgggg atcaactgca accgttcagg atcaggtaaa ttcagcctta aatgcctatc
      601 gtgcacaggg cttatcagct tggggctact aagaacagat aacagcgtta aaaacctatc
      661 atcttgtgtg atgataggtt tttagtatcg ttttacaatg actggataat ctcaatcacc
      721 tcttggggtg tgtgtccaat gtattgtgcg ccatgtgctt gtaaatcctc ttgacaacca
      781 aatccccaag taactccaag tcttgtaatg cctgcttgtt taccaccaat catgtcaaat
      841 ttggtatctc caacaattat agcttctttt ttattaatag caaaatcttg taagcatgcc
      901 ttgacgatat ccaacttgtg acaccgatta gaaatagagc ctaggatagc tttgaaataa
      961 tggctaatcg ttaaatcctg aagcatttgc cttgccatag gttcatattt actagttgtc
     1021 acatagaggt caagaccttc ttgcgagaga ttatctaata gctctgtgat tccagaataa
     1081 agccttgctt ggtaaatgcc taattccctg taaaaatctc taaagtgtgt tatagcaacc
     1141 tcgacatcat gctgattcct aaaaaatgct gaaaaggtcg cttctaaggg tggtccgatg
     1201 taagacgata atatgctatg atcaggacaa gggattttca ttttttgaaa ggtgtattca
     1261 aaggcattta gtattcctat actagaatcc accaaagtac catctaagtc aaataggatt
     1321 gctttcatga cgtctcctca gtctatcgtt acttgattat attagtctcc gaaaatttct
     1381 ttactatacc gtctacctgt tggggttgct gctaatcctc cctcagctgt ctccttaaag
     1441 gctgttggca ttgcggcacc aacctgatac atagcatcaa caacctcatc tacaggaatt
     1501 tgtgactgaa tattcgctaa tgccatatca gcagcaacaa gagcaaagct tgatcctaat
     1561 gcattacgct taacacaggg aacttcgact aagccagcaa caggatcaca aaccaatccc
     1621 aatagatttt tgatcacaaa ggctaccgct tggctagcct gataagcggt accacctgct
     1681 gccttaacaa gggctgcagc actcattgca gaggcagagc ccacctcggc ttgacagcct
     1741 ccttctgctc cggagataga ggcattattt ccaatgacta agccaaaggc acctgctgta
     1801 aagagaaagt ccagctgttc cttttctgat agcttgagct tatcaatagc aacagcaagg
     1861 acagcaggta gacagcctgc acttccagca gtcggggttg cacaaacaag tcccattttt
     1921 gcatttagct cattgacagc catagcattt ctcacagctg ttaaaatggt ttgatctgaa
     1981 agcccctttc cttttttgat gtaatgatcc atcttaagag catcaccgcc agtcaatccg
     2041 ctaatagatt tggttgctgt caatccgctg acaacagaat ccttcattac ctgtaaatgc
     2101 tgtgacatga tggataggat ttctgccctg cttcgaccag tcatttcaac ctctgtagca
     2161 atcatcagct ctgctacatt accatcaaac ctatcatcag cctgcttgac aagctcttca
     2221 attgtgtaaa acataatata cctttctagt caaagaaatt gacattatgc agattaggaa
     2281 tagttgcaat ctgcttgaca gcaacttgac aatcacgaga atcaacctca ataatcataa
     2341 tggctttctc acctgcactt tcacgagtca cagtcatttg agcgatatta atatcactag
     2401 ctgacaatat atctgtaacc ttagcaatca ttccggggat atcttgatgg acaataatca
     2461 aggttggagt attcatagac aaggaaacag aaaaaccatt tagctctgtg acctgaatgt
     2521 ttcctcctcc aattgacaca cctgtaatgc tcattgcttt atcagccttt ttgacactaa
     2581 tctttacagt attggggtgg ggagcattgc tatcctttaa aatatcccaa taaattttaa
     2641 tgcccttttg atgagcaatt tcaagagaat tcttgatgtt tggattatcc gtatccatgc
     2701 ccataatacc agctactagt gccttgtcgg taccatggcc ttgataggtc ttagcaaatg
     2761 aattgtatag atgaaaggtc acctcatcag gaatttctcc aaaaatggag tggacaacct
     2821 ttccgattct aacagcacca gcggtatgac tgctcgatgg tccaatcatc actggtccaa
     2881 tgatgtcaaa aactgattga aatttttgtg tgttcatata tgctccatgc tctttttatc
     2941 ctttttatta taacaaatcg ctaatcaaat gtcgtttgtt atgaaaaaag atattgttgg
     3001 aaataagaga caatactgtt ataatagtca tgcgtctagc ggcgcttcaa atcgaccttc
     3061 aaatcgagct ttgagaaaac acttggacaa agacaaaaaa tatagaaatg aaccatttgc
     3121 tagagtcttg tttaggcaag ttgattcgtt ctattctttt tctcatgtcc ttgtatctta
     3181 tattgatggg agaataaatg atgacagata actcgaaaac acgtgttgtt gttggcatga
     3241 gtggcggtgt tgattcatct gtaactgcct tgctgttaaa ggagcaggga tatgatgtga
     3301 ttggcgtctt tatgaagaat tgggacgata cagatgaatt tggtgtttgt acggcgactg
     3361 aggattataa agatgtggca gccgtagccg atcagattgg tattccttac tattctgtta
     3421 attttgaaaa agagtattgg gatagagtgt ttgagtattt cctagcagaa taccgttcag
     3481 gacgcacccc aaatcctgat gtcatgtgca ataaggagat aaagtttaaa gcctttcttg
     3541 attatgcgat gacattgggt gctgattatg tggcaacagg tcactatgcc caaatcaaac
     3601 gtgatgagaa tggtgtagtc catatgctgc gtggtcttga taagggtaag gatcaaacct
     3661 attttttaag ccaactatca caagagcaac tccaaaaaac catgtttccc ttggggcacc
     3721 tgcaaaaatc agaggtacgt gctattgctg aacaagcagg ccttgcaaca gcaaagaaaa
     3781 aagactcaac agggatttgt tttattagtg agaagaattt taagaccttt cttagccatt
     3841 atttaccagc tcaaaagggg cgtatgatga ctgttgatgg tcgtgatatg ggagagcatg
     3901 caggcttgat gtattatact attggccaac gtgggggact tggcattggt ggtcagcagg
     3961 gtggagataa caagccttgg tttgttgttg gaaaagacct ttcacaaaat atcctttatg
     4021 ttggtcaagg cttttaccac gagtccttaa tgtcaactag tcttgacgct tctgtcattc
     4081 agtttacaag agaagttcct gaagaattca ccttagaatg cacagcaaag ttccgctatc
     4141 gtcagccaga ttctaaggtg acggttcatg tcaagaaaga caaagctaag gttgtttttg
     4201 ctgagcctca gcgtgcgatt acacctggtc aagcagtcgt tttttatgat ggtcatgagt
     4261 gtcttggtgg tggtattatt gatatggcgt ataaagatgg cgagccttgt caatatattt
     4321 agcttgacat gttaattgac agatgtgtca ataaagttga cggttttgtc atctgataag
     4381 tcttgacaag ctggcagatt ttgatagaat aaggttaaca ataacgatga tggtcaaagc
     4441 tcatgggaat tgtaagtctt tttggcttac agctttctca ggttttgact atttttatag
     4501 cttaaaaaca gtgtcaagga gaaaagatgg ttcaggattt tagaacaagg atagcagacc
     4561 atagctttgg tgttagggct tcagcgttaa taattaagga tggctatatt tatcttgcca
     4621 aatcacccaa agaggactat tatcttttag gtggtgctat tcatgttgga gaaagcacag
     4681 aagaagctgt caagcgtgag gttctagagg aggtaggagc tgaggtttca gttgctcagt
     4741 tagcctttgt ggttgaaaat caattttgtc tagaaggagt gaactttcat cagattgagt
     4801 ttcattatat tgtgagtcta ttatctgatt ctagcccttc tgtagttgag ggtgattgta
     4861 ctagggtttg tgagtgggtt gctcttgatg atctagataa gataaggctc aatcctagtt
     4921 gtttaaaaag ggctataaag cattgggaca ggcagcctca gcatataaaa catattgaga
     4981 taaaggagta gatatggtac atgaatttac agaatcctac gatgtcatcg ttgtaggagc
     5041 aggacatgca ggtgttgaag ccagcttagc ggctagccgt atggggtgta aaaccttatt
     5101 agcaacgata aatcttgata tgctggcttt tatgccatgc aatccctcta ttggagggtc
     5161 agctaagggt attgttgttc gcgaaattga tgctcttggt ggagagatgg ggaaaaacat
     5221 tgacaaaacc tatatccaaa tgaaaatgct caatacaggt aagggaccgg cagttcgagc
     5281 attacgagct caagcagata aaagcttgta tgcacgtgag atgaagcata ctgttgaaaa
     5341 gcaagaaaac ctcactcttc gccagtctat gattgatgat attttagtag aaaatggtag
     5401 ggttgttgga gtgctgacag caacagggca aaaatatgca gctcaggcag tgatcataac
     5461 aacaggtaca gctcttcgtg gtgagattat ccttggagaa ttgaaatatt cgtctggccc
     5521 gaataacagc ttggcctcag tgacactagc tgataatttg aaaaagcttg gtcttgaaat
     5581 tggccgcttt aagacaggaa ccccaccacg tgtcaaggct tcttctattg attatgaggt
     5641 gacagagatt cagcctggtg atgtgactcc aaatcatttt tcctttatgt ctaaggacaa
     5701 agattatttg gctaatcaga ttccttgctg gctgacctac actaatcaga ttagtcatga
     5761 tatcatcact aaaaacctat atcgagcacc tatgttttca ggagtcgtca agggagtggg
     5821 cccacgctat tgtccatcaa ttgaggataa gattgtacga tttgctgata aagagcgtca
     5881 tcagctcttt ttagaaccag aaggctttga cactgaggag gtctatgttc aaggtctatc
     5941 cacaagtctt cctgaggacg tccaaaagga attggttcac tctattaagg ggcttgaaaa
     6001 tgctgagatg atgagaacag gctatgctat tgagtatgac attgtattac ctcatcagct
     6061 tcgtgctacc cttgaaacaa agatgatttc agggcttttt acagctgggc aaaccaatgg
     6121 aacctcaggc tatgaggaag ctgctggtca aggccttgtc gctggtatca atgctgcttt
     6181 gaaggttcag ggtaagcctg agctcatttt aaagcgcagc gacgcttata ttggtgtaat
     6241 gattgatgat ttggtaacca aaggaacctt ggagccttac cgtttgctga catcacgcgc
     6301 agaatatcgt cttatccttc gtcatgataa tgcggacatg cgattgactg aaattggtcg
     6361 tcagattggc ttggttgacg atgagcgttg gtctgccttt gaaatcaaga aaaatcaatt
     6421 tgacaatgaa ttaaagaggc tagatagtat caaattaaag ccaatcaaag aaaccaatgc
     6481 tcgtgttcaa aagcttggct ttaagtcctt gacggacgca atgacagcta aggaatttat
     6541 gcgtcgacca gaggttgact atgccactgt agtgtcattt ataggtcctg ctgctgaggg
     6601 attagatgct aagctgattg agctactaga aactgagatc aaatacgaag gctatatcaa
     6661 aaaggccctt gatcaggttg ctaaaatgaa gcgtatggag gaaaagcgga ttcctaagac
     6721 cattgattgg gacgctattg actcaattgc tactgaggca aggcaaaaat ttaagaaaat
     6781 caatccagaa accattggtc aggctagtcg catttcaggt gtaaatccgg cagatattag
     6841 cattttaatg gtttaccttg aaggtaatgg aaaggctcgc cgtaaaacat aatagtcatc
     6901 aaattgtaat ctcaaaacca ctgacagctc tgtatttcag ggctgtttta tggtataata
     6961 cgggattaag aggttaaaga tgaaaagatt tcgttttgaa accattcatt taattatgat
     7021 ggagttgatt ttattcggct tactagcctt atgtgttaga atcatgcaat caaaaatgct
     7081 gattacacta gctatttttt tagtgttgtt gtttgttgcg gccttgcttt ggtatcaaaa
     7141 aaaggtttac gaattgtctg atttagacca cattgagcta ttgaacgaac aaacagaaaa
     7201 taatttaaaa acattactgg ataacatgcc agttggtgtt attcagtttg atcaagaaac
     7261 caatgctatt gaatggtaca atccttacgc agagctgatt ttcactgatg aggccggttt
     7321 tttacaggaa cagatgatcc aacagcttct cactgataag cgtaaaagtg atatttctca
     7381 aacctttgag gtttctggca atcgatacac gtcttatatt gatgtggcat caggtatttt
     7441 ttactttttt gatagctctg ttggtagtag acaatcagca gattctagct tgctaaagcc
     7501 agttattggt attatttctg tggataatta tgacgacatt acagatgact tatctgatgc
     7561 tgatacgtca aagataaatt catttgtggc taatttcata gctgagttta tggagtctaa
     7621 gcaggtattt tatcgacgtg ttaatatgga tcgtttttac ttttttacag actataagat
     7681 cttaaaaggg ctgatggacg ataagttttc tattttagag cagttccgaa aggaagccca
     7741 agaagcgcag ctaccattga ccctaagtat gggcatttcc tttggagagg aaaatcattg
     7801 tcaaattggt caggttgctc ttgagaatct gaatattgct cttgtccgag gcggagatca
     7861 gattgttatt cgtgaaaatg cagaccatac aaatccggtc tattttggtg gcggctctgt
     7921 ttctacggtt aaacgctcta gaactaggac gcgtgccatg atgacagcta tttcagaccg
     7981 tatcaaaatg gttgataatg tgtttatcgt aggtcaccgt aaactggaca tggacgcctt
     8041 aggctcggct gttggcatgc aattttttgc tagtaacatt attgaaaaca gctttgctgt
     8101 ctataatccg gatgagatga gtccagacat tgaaagagct attgagcgct tacaggctga
     8161 tggtaagaca cgtcttatca gtatttctca agcaatgggg cttacgaccc ctagatcact
     8221 gttagtaatg gtggaccact ctaagatttc cttaaccttg tctaaggaat tttacgagca
     8281 atttcaagat gttattgtcg ttgatcatca ccgaagagat gatgattttc cagataatgc
     8341 tatcttgacc tttattgaaa gtggtgcaag cagtgccgca gagctagtga cagaattaat
     8401 ccagtttcaa aatgcgaaga agcgcttaaa caagattcaa gcaagtgttt tgatggctgg
     8461 tattatgctg gatactaaga atttttcaac acgtgtcacc agtagaacct ttgatgttgc
     8521 cagttattta cgaagcagag gtagtgatag cgtcgaaatt caaaatattt cagcaactga
     8581 ttttgatgac tataagcagg ttaatgagat cattctcaga ggtgagcgcc ttagcgactc
     8641 cattatcgtt gcaactgggc ttgctgggca atattatagt aatgtcattg ctagtaaggc
     8701 agcagatacc atactatcaa tggcccatat tgaggctagc tttgttattg tagagacagg
     8761 agctgataag attgctatat cagcaagaag tcgtagtaag atcaatgtcc aaagaatgat
     8821 ggaaaagctt ggcggcggag gacatttcaa cttagcagcg tgtcagatga agcatatcag
     8881 tcttagcgag gctaagcagc tgttactaga aacaattgat aacacaatga aagaaacaag
     8941 agaggtagag tcatgaaagt cattttttta gttgacgtta aaggaaaagg aaaaaaagga
     9001 gaaatcaagg aggttcccac tggttatgct cagaattttc tgattaagaa aaatttagca
     9061 aaggaagcta gcagtcaagc aattggccag ctaagagggc agcaaaaagc tgaggaaaaa
     9121 gcccaggctg aaatcctagc agaggctaag gctgttaaga aaatcttaga tgacgaaaaa
     9181 actcgtgtcc agtttaagga aaaggttgga ccagatgggc gtacctttgg ctcaattaca
     9241 gctaagaaaa tttccgagga attgcaaaag caatttaagg tcaaggttga caagcgtcat
     9301 attgttttag atcaccctat tcgtgctatt ggtcttatcg aagtgccagt taagctgcat
     9361 aaagaagtga cagctgaaat aaaactaaac attgctgagg catagcacat cagcctaaaa
     9421 aagatttgga ggtgctgagt ttgcctgaag ttgctgagtt acgagttcaa ccccaagatt
     9481 tattggcaga gcagtctgta ctaggctcta tctttatttc cccagacaag ttgattaccg
     9541 ttagagaatt tatcggtcca gaggattttt ataagtattc tcataaggtc attttcaggg
     9601 caatgataag gcttagtgat cgaaatgatg ctattgatgc aacaacggta aggacgattc
     9661 ttgatgatca aggggacctt caacatattg gtggcttgtc ttatattgtt gagctggtta
     9721 atagtgtacc taccagtgcc aatgcagaat actatgctaa aatagtagct gaaaaggcta
     9781 tgctacgcga tatcatcaat aggttgacag agactgtaaa cttagcctat gaaggagcat
     9841 ctgactcgga ggatattatt gcaagtgctg agaaggcctt ggttgatatc agtgagcata
     9901 gcaatcgcag tggctttcgt aagatctcag acgttttaaa gattaattat gaaaatcttg
     9961 aggttcgttc taagcagaca tcagacgtta caggtttacc aacgggcttt agggatcttg
    10021 acaagattac aacaggttta cacccagatc aactgattat tttagcagct cgtcctgcag
    10081 tcggtaagac agcctttgtc ttaaacattg ctcaaaatgt tggtacaaag caaaagagag
    10141 cagttgccat tttctcctta gaaatgggag ctgaaagcct tgttgatcgt atgctggccg
    10201 ctgagggaat ggtcaattca catagcttga ggactggtca gttgactgat caggactgga
    10261 ataatgtgac cattgcccaa ggagccttgg cagaagcacc tatctatatt gatgatacac
    10321 ctggcattaa gattactgag atcagagcaa gggcacgtaa attgtctcag gaggttgagg
    10381 gaggcttagg gctaattgtc attgattacc tccaactgat cactggtaca agacctgaaa
    10441 atcgtcagca agaggtttct gatatttcaa ggcagctaaa gattttagct aaggaattaa
    10501 aagtgcctgt tattgctttg agtcagcttt ctcgtggtgt tgagcagagg caggacaagc
    10561 gtccagtttt gtctgatatt cgtgagtctg gctctatcga gcaggatgcg gatattgttg
    10621 catttttgta ccgagatgat tattatcgta aagaaagcga cagcacagaa gaggctcttg
    10681 aggataatac aattgaggtg attcttgaga aaaatagggc aggtgcgcgt gggacagtta
    10741 agctgatgtt tcaaaaggaa tacaataaat tttcgacaat agctcaattt gaggaaagat
    10801 aagaaagagg gaaagagaat gagtgatgca tttacagatg ttgccaaaat gaaaaaaata
    10861 aaggaagaca ttaaggctca tgaaggtcag ttggttgagt taacacttga aaatggtcgt
    10921 aagcgtgaaa aaaataaggt tggcagattg atagaggttt acccttcttt atttatcatt
    10981 gagtatcagg ggaacccaga tgcttcaggg gaagcgaata attcttatgt tgagtcttat
    11041 acctattcag atattttgac ggaaaaaaca ctgattcgtt attttgattg aaaaatcaat
    11101 gcccatttag ggctttttct ttacactttg ttgacagctg tgtaaagata tgaatcaatt
    11161 tgaagccttg aagaacttat tagcaaatga atgaagcccg gactaataat agggactagc
    11221 tttcttgaaa agcagttact ctgagactct cggtattaga tatcaaaaca taatatgcta
    11281 ttttcaaaga atttcctatc ggtattaaaa agccttgttt actcgggaag tgttgtgtaa
    11341 aagcttgttt gccatatgat taacatcatc tttgagctta cagctaacca tttttgatga
    11401 tatgatatta aaaatgtaaa aaaaacttga atcaatacct ttttcatgtt acaattagtt
    11461 ttgtgtgaaa taacagcaga aaaatatgaa gctcgtcaac aggcggttaa ctaaattgag
    11521 taacctttgc tgtttaggcg aaaacctcct gcacgaatca ggatttttca aacagttatt
    11581 tcctcgttat attttttaga ggaggacatg atacatgtca cgttatactg gtccatcatg
    11641 gaaacaatca cgtcgtcttg gcttgtcatt gacaggcaca ggtaaggaat tggcacgtcg
    11701 taactacgta cctggtcagc atggccctaa caaccgtagc aagctttcag aatatggctt
    11761 gcaacttgct gagaagcaaa agcttcgctt ttcatatggt atgggggaaa aacaattccg
    11821 taacctattc gtacaagcta caaaaatcaa agaaggaact cttggtttca acttcatgct
    11881 tcttttagag cgtcgtcttg acaatgtggt ttaccgctta ggtcttgcaa ctactcgtcg
    11941 tcaagcacgt cagtttgtta accatggtca tattcttgtt gatggtaagc gtgttgatat
    12001 cccatcattc cgcgttgaga ttggccaagt catctctgtt cgtgaaaaat caatgaaggt
    12061 tcctgcaatc cttgaggcag ttgaagcaac tcttggacgt ccagcttttg tttcatttga
    12121 cgctgaaaag cttgaaggat cattaactcg cctcccagag cgcgacgaaa ttaacccaga
    12181 aatcaatgaa gcacttgtcg ttgaattcta caacaaaatg ctttaagata agactttata
    12241 ttataagaag cccacaacag tgggcttttt tggttgagcg gttagctgat ttatgtaccg
    12301 accccaaagg ttagaccaaa agtctaacga ttggaggtcg gtattgttag gcataaagat
    12361 cattataaac tcagtaagaa atagtttaca aagttgtttt ttggtactgg atttgacatc
    12421 attagtgcag gactatgttt tagatagcat ttttaagacg aaacgagtca tttcctgagg
    12481 ggattctttt tttcctttag caatccagct ttggcagaca ccgaaaaagg catgtgctag
    12541 gtagatgctt cgatattcct tttcggttgg ggacaagatg tccttactga acttgtcctg
    12601 aagatcggta gtgatcaaca gacgaacctt gttaatgata aagctttgga tttctcgggt
    12661 accattggag gatagcagag cagatagtag ttgctctcgc ttgagaaatt caaatacttc
    12721 taaaaaagca tgctccttgt tttggtattc tttttcaaaa atgtattcta atttgtgaaa
    12781 aaaggtttgt tgatagtaat caatcatctc atatttgtct ttatagtgag tataaaagct
    12841 agaacgacta atgcctgcca ttttagcaag ctgaacggtt gttacatcat cgaagctttc
    12901 ggtttttagt aagctcacca ttgcattaag aatggccttc ttggtttgct gcttgcggct
    12961 atccatcatt atctcctttt gaacacttgt agacattatg tctaaaaaat ttattttttc
    13021 cttgtaaaat gtcactttat ttgtataata tattttatca taatttttga acagtatgtc
    13081 tatttggaga aaaaataatg ctagaaggat taaaagcaat aatcaaaaat cgtaagctag
    13141 tagtgacaat gattggggtt gctctagtac cagctctcta taatttgtcc tttttagggt
    13201 ccatgtggga tccttatggt cgggttgatc agttgcctgt agcagttgtg aatcaggata
    13261 agcctgctta cttgaataac aagagactga ctattggtaa cgatatggta gacaatatgt
    13321 ctaaaaataa ggaattggat tatcattttg tggctgcaga taccgcacaa aagggcttgg
    13381 aaaagggtcg ttattatatg acgattacgt tgccaaagga tttgtcacaa aaggccacta
    13441 cgctattaga tcagcagcca gagaagctga ttgttagcta tcaaactagt aagggccata
    13501 gctttatcgc ttctaaaatg ggtgaatctg ctatgaatca cttgagagag gctgtttcta
    13561 aaaatataag gaagacctat atcacctccg tttttaagag catgcatcag ctccaatctg
    13621 gtctaaagga agcttcaaat ggcggtcagc aattagccgc tggcttagta attgctaggg
    13681 caagtagtca gctaatgtca aggcatttga acaccttgtc tgaatcaagt gctcgcttgt
    13741 ctcaaggagc gggtaatcta tctagtggta tagctgccta tacagccggt gttggtcagc
    13801 ttgataccgc gggcttagga cagctagcag ctgatatgcc agcgtatcta gatggtgttt
    13861 ctcggttatc caagggtgct aatcagttaa atgctggctt gacccaattg gctctaggaa
    13921 gtgatctgtc tcaagacaaa caagctaata ttcaagcttt aatggctagc ctaccaaagc
    13981 ttaatcaggc tatccagcag ctaaagacca atctttcctt gtctttggca ccaaatgtgg
    14041 actcaggagc cattgctaag catttagccg atatgacgcg tttagtgcag gagcttgtgg
    14101 tagatgatac tgctgacaag aacaatcagc tagccgctct acaagctaca gctacctatc
    14161 aaggtctcaa ctctgagcag caggaggagc tgagctcagc tatttccaat acttcaacta
    14221 aagtaacaat atcagcaaag gctatgttga catcactgca agccatgtct gaggagctag
    14281 aggctatgtc aacaagtgct ggtgtagctg atcaactgag ggactttaaa gcacttgtta
    14341 atcagctggc ttatcaagct gatcaaatcc tacctagcac aggcaaggca ttgtcagagc
    14401 tttcaactgg tttaagggct gttcactcag cgacaacagc ccagctctta tcaggtagtc
    14461 aagctcttgc tggcggcttt aatcaattga cagctaagaa tgaagctctt acagcaggcc
    14521 tgtctactct tgctacaggg gcaacagctc ttaaccatca atccagtcaa ttattagcag
    14581 gtggacagca gcttacagta ggcgctaatc agctagcttt tggagccaat cagctctcct
    14641 ctggcagctc tcagttgaca gatggcttga caactctgtc aacaggtctg tcaagcttaa
    14701 cgacctcact atcaaaagct tctgaccagc tttcaatggc ttgggtagag gaccagaatg
    14761 ctgatatggt atctgatcca gtagcgttat cagagaagga caaggataag gttaggacca
    14821 atggtattgg catggctcct tatatgattg ctgtgtctct aatggtagtt gccttgtcta
    14881 caaatattat ttttgcagag gccttatctg gtaagccgat taaagataga tgggattggg
    14941 caaagcaaaa attactgatc aatggcatga tttcgaccgt tggctctgtt attctttacg
    15001 ctgcacttca actgctgggc tttgaagcta atgacggtat caagacctta ggctttatta
    15061 tgctgagtgg atgggccttg atggctttag tgactgcatt ggtcagctgg gatgctcgat
    15121 atggtgcctt tgcttcgtta attatgctgt tgctacaggt tggtgctgcg ggtggttctt
    15181 atcctattga gttgagtggt cagatcttcc agattctcca tccttatctt ccaatgtctt
    15241 atattgtctc tggccttcgt cagacaatat cattaactgc ccagataggt ttagagacga
    15301 gtgtattagt tggctttttg ttaagcttta tggctatagg agtgctgatt tatcgtccaa
    15361 aggacaagca atcgtcctag ataatagctg agataacagg ttatcgttaa acagtagata
    15421 taataaaaaa gcttctagaa attgtggttt aagctctttc tagaagcttt ttttatggtt
    15481 ggtttagctt acggagataa gaccattatt attggaaatg gtaagctgtg ctttaaaggg
    15541 tgtttgacga cctgcttctt gactaatcgt tacaaatcca ttattatttg aagcctttac
    15601 gtcatagtag atgaggtttt ctctaggaca attgatgtca atgattccat tcttattgat
    15661 gatagtgatg tcattggaaa aggacagctg ctgccctatg atattaccgt ttttgttttc
    15721 aatgaaggtt tctgttagct gacttgcttc taatctgatg tttccattgt tattgttcag
    15781 ctggcaattt attagggtgc tattgtcaca gctgaggtta gcatttttgg cttgacattt
    15841 actagactgg atattgcaat gctctaaaat aatgttccca tttttgctgc ttaggttgac
    15901 agtgctatct gataaatgac tgatagaaat cgttccattg taagtgttag agacaatgct
    15961 atcacaatgt atatgcctta tggtgacatc gttgttgtca ctttctccag agattttttt
    16021 caggtggtgg ttgacaggta gtgtcaaggt aatgggttga tattttgcaa gccagcggtc
    16081 taggaaatga aagccatact gtattgtttg tactgctgag tcttcaatga tattgagcat
    16141 gccgtcacta tcttggctta ttgtgatgcg attatcatcg tatgaaatag tagggtaagg
    16201 aatgtcagca gtttcaatgg ttaaatcatg gttaagcaga ctatagcgaa tgtcaactat
    16261 tggctcaagc ttttgtgagc ttgcttctga ctttgttttg ttgtcaactt cccaattcgt
    16321 ccagtcatct tcgtctgttt tttcggggag atctaaggct tttaatagct ccttggcaat
    16381 gtcctctgga tttcccagtt ctttaagaat agcttgttca tggtcaggac cagcctcgtc
    16441 aaaatactct gtaaaatggt caatgatttc ttggtaatcc ttttgaggta aatggttgat
    16501 ctgctgcttt agcttgtcta gaaaatcttg tttagtcatt atgatatcct cccttgatta
    16561 atgaattgat aggtcgcttt gattgacagt attggctatg tcagagtgaa atgaagtagc
    16621 tcctgttgct gcgtctgtgt taagcttggc gtttgaaaaa cgagagctga gcttgatgtt
    16681 gcctcttgtt gtgacatgat aagcaatatc tcttggattt gctaatgtgg tattgatatt
    16741 aatatcgccg ccattaattg tgtttttctc cttgattgtg acatgattta tagcaagctc
    16801 ggaggggtct gtatagtcat agtcgttttc ttcttttgta tcagctacag tgatagaaga
    16861 gtctttgata ctgccgtcgt taagttctag ctgacttgag ttctcagcag cttcataata
    16921 atctgcttta ggtaattttc gtaggtattt gtctagctct gctaggtatt catctcttgt
    16981 catgccttaa tctcccttca ataatgccat ctagggtggc cttgtagctt tgccattctt
    17041 cctttaagaa aatcagctgc ttttcgcctt tggctgtaat ggtgtaatag ttacgcttgc
    17101 gaccttgatg ttcctgacta taggtagtta aatagtctga tttctctagc ttttttaaaa
    17161 tagggtatag ggttgattcc ctgatattag cgacaagctt aatggtttgg ctgatatcat
    17221 aaccatagga atcatgcttg tcgacaatag ataaaatcaa aaattcaatc aaggtagcag
    17281 atactggaaa atacatctgg ttactccctt cctgcctcgt atttatatat aattatttta
    17341 tatattaagt atagagtttc tgttttaata tgtcaatatt ttatatataa aaattttata
    17401 tatcatagag agtaatcgga gccatttctt gaccaaagga ttactatttt atactatgaa
    17461 agtagcttag tgatggatat gataaggaga aggacagatg aagagcatta ttgaacatta
    17521 tcaggctagg cccttgggtg aggagcgatg ttatgcggtt tgcttacctt tgatttggca
    17581 ggaagggcga tggcaggtct tatatgaaat cagaagccaa catatctctc a
//
LOCUS       DARYVE010000045        17428 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYVE010000045 DARYVE010000000
VERSION     DARYVE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17428
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            148..1398
                     /locus_tag="TVW25_001408"
     CDS             148..1398
                     /locus_tag="TVW25_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1379030.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1507..2388
                     /gene="truB"
                     /locus_tag="TVW25_001409"
     CDS             1507..2388
                     /gene="truB"
                     /locus_tag="TVW25_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1379031.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2402..3334
                     /locus_tag="TVW25_001410"
     CDS             2402..3334
                     /locus_tag="TVW25_001410"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1379032.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3377..3781
                     /locus_tag="TVW25_001411"
     CDS             3377..3781
                     /locus_tag="TVW25_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1379033.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3783..4061
                     /locus_tag="TVW25_001412"
     CDS             3783..4061
                     /locus_tag="TVW25_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1379034.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            4051..4827
                     /locus_tag="TVW25_001413"
     CDS             4051..4827
                     /locus_tag="TVW25_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1379035.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4844..6151
                     /locus_tag="TVW25_001414"
     CDS             4844..6151
                     /locus_tag="TVW25_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1379036.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6289..7155
                     /locus_tag="TVW25_001415"
     CDS             6289..7155
                     /locus_tag="TVW25_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1379037.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7166..8101
                     /gene="pstC"
                     /locus_tag="TVW25_001416"
     CDS             7166..8101
                     /gene="pstC"
                     /locus_tag="TVW25_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1379038.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8091..8978
                     /gene="pstA"
                     /locus_tag="TVW25_001417"
     CDS             8091..8978
                     /gene="pstA"
                     /locus_tag="TVW25_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1379039.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8995..9798
                     /gene="pstB"
                     /locus_tag="TVW25_001418"
     CDS             8995..9798
                     /gene="pstB"
                     /locus_tag="TVW25_001418"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1379040.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9812..10570
                     /gene="pstB"
                     /locus_tag="TVW25_001419"
     CDS             9812..10570
                     /gene="pstB"
                     /locus_tag="TVW25_001419"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1379041.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10641..11294
                     /gene="phoU"
                     /locus_tag="TVW25_001420"
     CDS             10641..11294
                     /gene="phoU"
                     /locus_tag="TVW25_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1379042.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11528..14065
                     /locus_tag="TVW25_001421"
     CDS             11528..14065
                     /locus_tag="TVW25_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1379043.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14484..15158
                     /locus_tag="TVW25_001422"
     CDS             14484..15158
                     /locus_tag="TVW25_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1379044.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15151..16461
                     /locus_tag="TVW25_001423"
     CDS             15151..16461
                     /locus_tag="TVW25_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1379045.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVSQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            16846..17265
                     /locus_tag="TVW25_001424"
     CDS             16846..17265
                     /locus_tag="TVW25_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379046.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            17262..>17428
                     /locus_tag="TVW25_001425"
     CDS             17262..>17428
                     /locus_tag="TVW25_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379047.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVV"
BASE COUNT         5236 a         3181 c         3905 g         5106 t
ORIGIN      
        1 tttaaagacc agcaaaatcc cttgggacac aaggggttag ctggtcttta cttgttttta
       61 agtgataaag tcgggagtct ggaaaaatca ttttctaggc tttttttgct ataatggcag
      121 tgagataatt gcaagaatgg agaaatcatg aaagaactaa aatgtcctca ttgccatacc
      181 ttatttacgg tcaatgagtc tgactatagt cagattttag cacaggtacg aggtcaagag
      241 tttgacaagg agttggcaca gcgcttagaa agtgagatga agctgcaaga agcaagggcc
      301 aataaccgct tccaagaggt gcttactaaa aaggagcagg ctattcaaag cctgaccaac
      361 cgcttggagc gtattgagca ggaacaggcc tatttgaggc aacaggagct agcccaaaag
      421 gataaagagc tcctagagct tcacaatcag ctagataagc tagagcttga gcagcaatca
      481 aggctccagt ctgcccttac agttgttgaa aaggaacgtg atcacctaaa aaatcagctc
      541 gtgctgcagg aaaaagaaag cgaactttct ctagcctctg tgcgcagtga ttatgaggtg
      601 cagttaaagg ctgtcaatga gcaggttgag ttttacaaga attttaaagc gcagcagtca
      661 actaaagcta ttggagagag cttagagctg tatgccgaaa ccgagtttaa caaggttcgc
      721 agctatgcct ttccaaatgc cagttttacc aaggacaatc aagtgtctca tcgaggctca
      781 aagggtgatt atatttaccg agagctagac aataatggtg ttgaaattct ctcaatcatg
      841 tttgaaatga aaaatgaggt tgacacgacc aagaccaagc ataaaaatag tgatttcttt
      901 aaggaattag ataaggatcg ccgggaaaag aattgtgaat atgctgttct tgttaccatg
      961 cttgaagcag acaatgatta ttacaatgca ggaattgttg atgtcagtca tgactatgac
     1021 aaaatgtatg tggttcggcc tcagctcttt attcatctca tcggattgct gcgtaacgct
     1081 gctcttaata gcttaaaata taagcaagaa ctggcgcttg tcagggagca gcacattgat
     1141 attacacatt ttgaggagga cctagagcat tttaagcatg cttttgctaa aaactaccag
     1201 tctgcaagca ataactttaa aaaagccgtt gatgaaattg ataagtccat caagcgtatg
     1261 gaggaggtca agcgctttct aacaactagc gaaaatcagc tgcgtttagc caataacaag
     1321 ctagatgatg tctctgtcaa aaaactaacc agaaataatc caaccatgcg cgataagttt
     1381 caagcaatca agccctagga ttatctcagt caggcttatt gatagaggct ttgttgcttg
     1441 tcaaaagcct tgtgaaatgg ttataataga taggctaatg atcaaaacaa taaacgaaag
     1501 taacacatga taaacggaat aatcaattta aaaaaagaag caggcatgac atcacatgac
     1561 gctgttttta agcttagaaa gctattacaa gaaaaaaaga ttgggcatgg agggacgctt
     1621 gatcctgacg tggtcggtgt tttgcctata gcagtgggga aggcaacgcg agttattgaa
     1681 tacatgacag aagcaggtaa aacctatgag ggagaggtta ctcttggcta ttcaacgaca
     1741 acagaggatg ctagtggaga gattgttgac caaacagtag tgcccttgag tttgactgaa
     1801 gcgatggttg atgaggcaat gacacaattt attggtcaaa tgactcagat tccaccgatg
     1861 tattctgcgg ttaaggttaa tgggcgcaag ctttatgatt atgcacgagc tggtgaagca
     1921 gtcgagcgcc ctaaaagaca ggtaacgatt gaccagtttg agcggacaag tcccttgacc
     1981 tttgcaggtg gtctttgccg atttagcttt agggtgagct gtagcaaggg gacttatatt
     2041 aggaccttgg cggttgatct aggaagaatg cttggctatg caagtcatat gtcttggctg
     2101 gttcggacag cttcttcggg tttaagtttg gatcagtcct ataccttgtc agagattgct
     2161 gagctgctgg ataaaaagga catgagcttt ttattgccta ttgaatatgg tgttagtgat
     2221 ttagccagag tagtcgttaa tgactgggag ctgagagagc tttcctttgg tagaaaaatc
     2281 gctctatcat gtgaggaaaa tctgttagcg gctttttatc aggacagctt gatcgctatt
     2341 ttagaaaagc aagaagggct ttacaagcca agaaaggttt ttatttagag aagattgata
     2401 tatggatata caacacatta aaagctatca ggagattgat gaatcagctg ataccgtttt
     2461 agtcttaggc tactttgatg gtctgcaccg aggtcacaag gctctatttg ataaggcaaa
     2521 ggaaatatca cgtcaggaaa gcctaaaaat agtcaccttg accttccatg agtcccctca
     2581 gctggccttt acacgctttt ctcctgattt tttacgacac attacctatc cagaaaaaag
     2641 gtatgaaaaa tttgctgagt atggtgttga taagctttat ttgcttgatt ttaccacgtc
     2701 attttcaaaa ctatcctctg atgatttcat tgaccactat attgggcgtt taagggtaag
     2761 gcatatcgtt gtaggctttg attatcactt tgggtgtgat cacgcagata gtcattactt
     2821 agctaaacgg ataaaaggaa ccgtttatag catttcagag gtcaaagaag accagatcaa
     2881 aatctcatca acacgtatca gaagtctgat tacagcagga gatgtcgcta aggctaatca
     2941 gctgcttggc tatgagcttt caacaagagg aatggttgtg catggtgatg cgcgtgggcg
     3001 aaccattggt tttccgactg ccaatcttgc acctattgat aggacctatc tgccagctga
     3061 tggtgtttac gtgacagatg tgctggttag aggaaagcgc tatcggtcta tgacgagtat
     3121 cggcaagaac attacctttg gtggtaaaga gctgcgatta gaggcaaata tttttgattt
     3181 taatgaggac atttatggag aaactcttga aattatttgg ctagatagga ttcgtgagat
     3241 gaataaattt agtgatgtta gcacctttat cagccaacta aagcaggata aagaagctgc
     3301 cataaattgg aaaaaagata gccaaggcta ttaaattttt gtataataag gtaagcacaa
     3361 ttaacagagg aaaagtatga ttaccttatt tctatcacca agctgtacta gctgccgtaa
     3421 ggccagagcc tggctcacca agcatgacgt tgactttcaa gagcataata ttattaccag
     3481 cccacttagt cgtgaggagc tgttagcgat cctatccttt actgaaaatg gaacagagga
     3541 tattatttca acacgatcaa aggtttttca aaaattggat attgatattg atgagctgtc
     3601 tatcatggat ttgattgatt tgatcgcaaa gaaccctagc cttcttcgta ggccaatcat
     3661 tatggatagt aagcgcatgc aaattggctt taatgaagat gagattaggg catttttgcc
     3721 aagggattat cgtaagcaag agctgcgcca agcaaccata aaggcagaaa tcgagggata
     3781 acatgtcaga tcattatcat tacccacttg atgtaagctg gagcactgaa gagataacat
     3841 cagtgcttca ttttttaaat caggtagagt tagcctatga ggctaaggta ggagcagagg
     3901 agctactcaa aagctatgct gcctacaagg agattgtaag aagcaaatca caggaaaagc
     3961 agattgaccg cgaattccaa caagccagtg gctattcaac ctatcaagct gtcaaaaaag
     4021 ccagagaaat tgagaaagga ttcttttccc ttggaagata aatacgcatt tgctaaaacg
     4081 atcatcaaag aggctggcct tctgattaag gatagaatga aagatagctt agccattgaa
     4141 atcaagacgc agcatgatga tttagtgacc aatgtagatc aagagacgca ggatttctta
     4201 attgctaaaa tcaaacaggc ctatcctagt gaccatatga ttgctgagga gggcggtatc
     4261 tgtcatgcta ttacagatgg caaggtttgg gtgctggatc ctattgatgg tacggtgaat
     4321 tttattgtac agaaagccaa ttttgcgatc atgatggctt attatgagaa tggcgtcgga
     4381 aaatttagtc tcatttatga tgtcatggca gatcagcttt tttcaggtgg aggagatttt
     4441 gctgttactt taaatgatca agtcctagca tcttatcagg ataagccgct tgatcgtagc
     4501 ttaattggct gcaatgcagg tatgctttca aggaacgatt acaacctgca ccagttgatt
     4561 gatcaaaccc taggagtgag ggtttatggc ggtgcaggca tttgcatgac taaggtgtta
     4621 aggcagcagc taatggctta tttctcttat attcaacctt gggattatgc agcggcagcc
     4681 attatgggcg aaagccttgg ctatgtcctg ttgaccttgg agggaaagca gccagacttt
     4741 cagtctagac agaaggtgat gtttgttccc aagtctaaac tagccaccat tcaatctctg
     4801 ctgaaaacaa acgagaatac ccaataagat taaaatgaaa agcatgcaat taccaaacga
     4861 ttttattgaa aaataccaac agctgctagg ttcagaagca aaagcttttt ttgagagctt
     4921 tgatcagcct gccatcagtg cctacaggat aaatccctta aagcaccaat cggtctgcct
     4981 tgatcctcct attcctgata caccatgggg ttactacggc agggtatcag gaaagtctcc
     5041 taaccacgtg tcaggtgtgg tgtattccca agagcctgct gctcaaatgg ttgctcaggt
     5101 ggcctcacct gccaagggaa ctagagtgtt ggatttggca gcagcgccag gtggcaagtc
     5161 aactcagtta cttgcctatc tagagaatac aggactttta gtgagtaatg agatttcgac
     5221 caaacgcagc aaggccttag ttgaaaatat agagcgcttt ggtgctagaa atgttattgt
     5281 gacaaatgag tcagctgaca gactggctgc tgtttttcca gaatattttg acactattgt
     5341 ctttgacggg ccttgctctg gtgagggcat gtttcgcaag gatccaaatg ctgttagcta
     5401 ttggcacaag gattacccag cagcatgtgc tagcctgcaa agatccattt tagcagaggc
     5461 gatacctatg ctaaagccag gtggtcagct gatttattcg acctgcacct ggtcgcctga
     5521 agaaaatgaa gaggttgttc gctggctact agaaagttat gattttcttg agctggagca
     5581 tatccctaag atcaatggta tggcagaggg gatcggtatg ccacaggcag ctagaatgta
     5641 ccctcatcgc tttaaaggag agggacagtt tgttgctaag ttaaaggata ctagatcaac
     5701 gatttcctct tcaagctaca aatctccaag gtctaacctc actcaagagc agctgaggct
     5761 gtggcaggat tttgaaaaaa atcatttgaa cataaccttg tctggcctat tacaggtctt
     5821 tggtgatcgt ttgtacttgt taccagatgg cttaccctgt cttcgatcgc ttaaaatagc
     5881 aagaaatggt ctggaattag gcacttttaa gaaaaaacgc tttgagcctt cctatgctct
     5941 gggcttggca ttaagacctg aagaggtcag cttatctgtt gagattaacg aagaggactt
     6001 tgtcacatac gcctcaggaa ataccattac cttaccagaa tcttatgcta cagattggta
     6061 tcagctggtc attaacggaa atggtctggg ctttgctaaa atagttggtc gcacccttaa
     6121 aaatagcttc cctaagggct tacgttttta aggaatggca taccattaaa tttttataaa
     6181 tttaaataaa acttcttcca aagcattgtt agatatgtta atataaagaa tatgctgaag
     6241 cttaattctt cgctataaac ctttattttt atgaatagga atagaataat gaaatcgaaa
     6301 aagaaattct ttttgttaag tcttttagcc ttgtcggctt tctttttgtc agcctgctca
     6361 agctggattg ataagggaga atccataaca gcggtaggct caacagcatt acagccctta
     6421 gtagaagccg cagctgatga gtttggaagc aataacctcg gaaaatctgt taatgttcaa
     6481 ggaggcggct ctggcactgg cttatcacag gtgcagtcag gtgctgttca ggtaggcaat
     6541 agtgatgtct ttgcagaaga aaaggacggg attgatgctg ctaagcttgt tgatcaccag
     6601 gttgccgtag caggacttgc tgtcattgcc aatcctaagg tcaaggtatc taatctcaca
     6661 agcaagcagc tacaaaagat tttctcaggt gaatatacca actggaagca ggttggtgga
     6721 caggatcttg ctatttcagt gattaatcga gcggcaagct caggctcacg tgctaccttt
     6781 gatagtgtca tcatgaaggg tgttactgct aagcaaagtc aagagcagga ttctaacggt
     6841 atggttaaat caattgtgtc tcagacaccg ggggccattt cttacttatc ctttgcctat
     6901 gtggattcgt ctgtaaaatc attacgattg aatggcttta aggccaatgc caaaaatgta
     6961 gcaaccaatg attggcccat ctggtcctat gagcatatgt ataccaaagg caagccagac
     7021 ggcttaacca aggaattttt ggattatgtg ctatcagatg aggtccaaaa aaccattgtg
     7081 acacatatgg gttatattgc tatcactgat atgaaggtcg tcaaatccta tgatggaaaa
     7141 gttacagata aataatgggg gaattatgaa aaatcaggaa ttagctaagc aattagcctc
     7201 accatcaaaa aattcacgac ttgaagcatt tggtcgtacg attacctttt tttgcctcgc
     7261 cttaattgtt tttatcgttg caatgatttt actttttgtg gctcaaaagg gcttgtctac
     7321 cttttttgta aacaaggtta atctttttga tttcctattt ggtacagagt ggcagcctag
     7381 cgttaaaaat gctgccggtg ttccttatct tggagctctt ccgatgattg ctggatcgtt
     7441 tttagtcacg attttatcag ccttggtggc aacaccattt gccattgggg cagcagtatt
     7501 tatgactgaa atttcaccca agtacggggc aaaactatta cagccagcag ttgaattgct
     7561 tgtaggtatc ccgtcagttg tttatggctt tattggcttg caggttgttg ttccttttat
     7621 tcgttctatt tttggtggaa caggctttgg tatcctatca ggggtctgtg tcttgtttgt
     7681 catgatttta ccgacggtta cctttatgac aacagatagt ctgcgcgctg ttcctcgtca
     7741 ttatcgtgag gcttctatgg ctatgggggc tacacgttgg caaaccattt ggcgagtggt
     7801 tttaaatgcg gctcgtcctg gtatttttac tgctgttatt tttggtatgg ctagagcctt
     7861 tggtgaggcc ttagccattc aaatggttgt gggaaattca gcagtcatgc cggcttcact
     7921 aaccactcca gcggctacat tgacctctgt attgactatg ggaattggta atacagttat
     7981 gggaactgtt caaaataatg tgctatggtc attagccctt gtcttattgc tgatgagtct
     8041 agcttttaat tcccttgtca aattaattac gaaagagaga aagagaaatt atgaacgcta
     8101 aaaaggttga taaagtagca actggtagct tgtatactat tgctggaatt attgtagcta
     8161 ttttagcttc cctaattctg tttattcttg tgcgtggcct acctcacatc agctggtcgt
     8221 ttttaacagg gaaatcatcg tcctatgaag ctggtggagg tattgggatt cagctttata
     8281 attcattttt cttgctggta gtaaccttga ttatttccat tcccctatca acaggtgctg
     8341 gcatttattt ggccgaatac gctaaaaaag gacctgtgac aaatgtgatt agaacctgta
     8401 ttgaaatcct atcctcattg ccatctgttg tggttggatt gtttggctac cttatttttg
     8461 ttgtacagtt tgaatatggc ttttctatta tatcaggtgc ccttgctttg acggtattta
     8521 atcttccgca aatgacaaga aacgttgagg atagcttgct gcatgtgcat catactcaaa
     8581 gagaggcagg gctagccctt gggctttcac gctgggaaac ggtttttcat gtggttattc
     8641 cagaggcctt gccaagtatt gtgacaggta ttgttttggc ttcaggtcgt atctttggtg
     8701 aagcagctgc tcttatctat actgcgggtc agtctgcccc agcgcttgat tggtcaaatt
     8761 ggaacccttt gagcgtgaca agccctattt caattttccg tcaatctgaa accctagctg
     8821 ttcatatttg gaaggtcaat agtgaaggga caatccctga tgcaacactt gtttctgctg
     8881 gtagtgcagc ggtgttgttg atttttatcc ttattttcaa tctatcagct cgctttattg
     8941 gcaagcgtat tcatgctaag atgacagcag caaaataaga cattggagag attcatgaca
     9001 gaatataatt ggaacgaacg tcatatcatt acatttccag aagaaacgat tgccctagct
     9061 actaaggatc tgcatgttta ttatggtagc aaggaggcaa tcaaggggat tgatatgcaa
     9121 ttcgaaaaaa ataaaattac agccctaatt ggaccctcag gctgtggcaa gtcaacctat
     9181 ctgcgcagcc tcaatcgcat gaatgacacc attgatattg ctagagtaac aggtgaaatt
     9241 ttgtatcaag gcattgatgt caatcgaaag gacatgaatg tgtatgaaat ccgtaagcac
     9301 ctaggaatgg tctttcaaag gccaaatcca tttgccaagt ctatttataa aaacatcacc
     9361 tttgctcatg aaagagcagg agtgagagat aaaagggttt tagatgagat tgtcgaaacc
     9421 tccctcaagc aggctgcact atgggatcag gtcaaggacg atcttcataa atcagccttt
     9481 accctttcag gaggtcagca gcagcgcttg tgtattgcta gggctatttc ggttaagccg
     9541 gatatcttgt tgatggacga accagcttca gcccttgatc ctattgcaac catgcagcta
     9601 gaagaaacca tgtttgagtt gaagaaggat tacaccatta ttatcgttac tcataacatg
     9661 cagcaggccg ctagagcaag tgattacact gctttcttct atttgggtga cttaattgaa
     9721 tacgataaaa cgcgtaacat tttccaaaac gctacctgtc agtccacaaa tgattacgtc
     9781 tcagggcact ttggttagaa agaaggatat gatggcagaa cctattttac aaatcagaga
     9841 tctttctgtt tactataata aaaagaaaac cttaaaggac gtgtccttag atttttaccc
     9901 aaatgaaatc acagcactca ttggcccttc agggtctggg aaatcaacac ttttgcgttc
     9961 catcaatcgc atgaatgacc tgaatccaga ggtaaccatt acggggtcaa tcgtttataa
    10021 tggacataac atttacagtc caagaacaga cactgttgat ttgcgaaaag aaattggtat
    10081 ggtctttcag cagcccaatc cctttccaat gtctatctat gaaaacgttg tctatggctt
    10141 gcgcctaaag ggcattagag ataaggctgt tttagatcac gctgttgaat cctctctcaa
    10201 aggagcctcc atctggagtg aggtcaagga taggcttcat gattcagctg ttggactatc
    10261 aggaggtcaa cagcagcgtg tctgcatagc aagggttctg gcaaccagcc ctaaaatcat
    10321 tttgttagat gagccaacat cggctttaga tcccatttca gccggcaaaa tcgaagagac
    10381 cctgttctca ctaaaaaagg attatacgat ggttatcgtt acccgctcca tgcagcaggc
    10441 ctcgcgcttg tcagaccgga caggcttctt cttagaggga gaccttcttg agtttggtcc
    10501 tactaaggca atgtttatga accctaagag gaaggaaaca gaagattata tttcgggtaa
    10561 atttggctaa gggatcttgt ttgtagtcta ggtatccgct ctgtttagga taataaatga
    10621 atcaatagaa agaaaaaatg atgttaagaa ctaaatttga agaagaatta gacaagctac
    10681 acaatcagtt ttactctatg ggaacagaag tcttgtctca aatcaataaa accgttcgtg
    10741 cctttgtcag tcatgaccgc gaattggcca aagaggtgat tgaggaagac gataccatca
    10801 atggatttga aacaaaatta gaaaaaaagt ctcttgaaat tatcgcctta cagcagcctg
    10861 tttcaaacga tttgcgaaca gttattactg ttttgaaggc ctcaagtgat attgagcgta
    10921 tgggagatca cgctgcctct atcgctaaag caaccattcg catgaaagga gaagagcgta
    10981 tcccgattgt tgaggagcat atcaacttga tggggaaggc agtcaagcag atggttgaag
    11041 aggcgctaaa tgcttatatt aatgcagatg atgccaaggc ctatgaaatt gctgcttcag
    11101 acgaaatcat tgataattat ttccgcgaaa tccaatctct agctgtcgaa gaaattcgca
    11161 agacaccaga tgccgtcttt gctggcaagg aatacttcca ggttctcatg tatttagagc
    11221 gtatcggtga ctatgctcgt aatatttgtg aatggattgt ctatttaaaa actggaaaaa
    11281 ttattgaatt ataagaaagt atggtataat gggggctggg tgaacttctc agttcctcgt
    11341 tttattatag cgattaaaag gttttagagg ctggagcttc agctgagctg actatcagct
    11401 gtcaagcttc tagacaaaat gaaagataac aataagctag tcgtctaagg gactagacgg
    11461 caggattgat tatattaaga atgtgacctt gtcccatcac taatttaatg acatattaag
    11521 gagttgtatg aaaaaagtag aacatcttat tgaaaagttt attcctgaaa attataatat
    11581 tttcttagac attaatcgca gcacaaaaac cttcacaggt aatgttgcaa tcaatggtga
    11641 agcattagat aatcaagtgt catttcacca aaaggacttg gcaatcaatg ccattttact
    11701 tgacaatgaa gctgttagct atcatgttga cgatgacaat gagcttgtgc gtgttgagct
    11761 gccagagact ggtatgatga cgcttgtcat tgaattttca ggtaatatta ctgacaatat
    11821 gactggtatt tacccgtcct attacacaaa agatggtgaa aaacaggagg ttatttcaac
    11881 gcagtttgaa agccattttg cgcgtgaggc ctttccatgt attgacgagc ctgaagcaaa
    11941 ggctaccttt gacttaagct tgacatttga ccaagcagag ggcgagattg ctctatcaaa
    12001 tatgcctgag gtcaatgctg agcgccgcaa ggagaccggt ctttggacct ttgagacaac
    12061 tcctagaatg tcttcttatc tgctggcctt tgccttagga gacttgcatg gcaaaacaac
    12121 aaaaagtaaa aacgggacaa cagttggtgt ttatgcaacc aaggctcacc cactgacctc
    12181 gctagatttt tcattggata ttgctgtacg tgtcattgat ttttacgaag actactttgg
    12241 ggttcgctat cctattccgc aatctctaaa tattgctctt cctgattttt catctggagc
    12301 gatggaaaac tggggcttga ttacctatcg tgaaatttac ctgttggttg atggcaattc
    12361 aacagcccgc agcagacaaa atgttgctct tgttgtggca cacgagattg cccatcaatg
    12421 gtttggtaat cttgtaacca tgaaatggtg ggacgatctt tggctaaatg aaagctttgc
    12481 caatatgatg gaatatgtag ccatcaatgc tattgagccg tcatggcgta tttttgagga
    12541 tttccaaaca acaggtgtgc cgctggctct taagcgtgat gcaacagacg gtgttcaatc
    12601 agtccatgtt gctgttaatc acccagatga gattaatacc ctgtttgatc cagctattgt
    12661 ctatgccaaa ggtagccgct taatgcatat gcttcgtcgc tggattggcg ataaggattt
    12721 tgcggcaggt ctgcgccttt actttgaaaa gcatcaatac cgtaatactg taggacgtga
    12781 tttgtggcag gctctttcag aagcttctgg taaagatgtt gctgcgttta tggacgcttg
    12841 gctagagcag ccaggctatc ctgtcttaac ggccagagtt gacaatgatc agttgattct
    12901 cagccaaaag cagttcttta ttggtgaggc aagcgaccaa aagagactat ggccaattcc
    12961 actaaatgcg aactggaaag gtcttcctga cgtactgaca gaggagtcca tcgttatttc
    13021 aggctttagt caattagccg cccaaaataa aggaacactt cgctttaata cagaaaatac
    13081 agcgcattac attacagatt atcagggaca gctctttcat agcttagttg atgatttgaa
    13141 gcatcttgac aacacctctg cccttcaagt gattcaagag cgccgcttgc tggctgatag
    13201 cggtctgatt tcttatgcag agctggttga cttaatcgct cagctagatg acaaaaaatc
    13261 ctatatggtt gctgcagctg ttcagcaggt tattagaggc ttagagcagt tcattgatga
    13321 aggaacctca gcagagcagt ccttcaatcg attgatttct tctattttcc aagaggactt
    13381 caggcagctt ggatttgaaa agagggcaaa tgaatctgat gaagatgaaa tggttcgtca
    13441 aattgcttta catcacctgt tggttggagg caatcgtgat gtgatcaagc aggccaagac
    13501 tatctttgaa gcttatgcaa atcgtatcga agccattcca gcagccattc gccgctcggt
    13561 attggtgagt cagatcaagt attttgaaat agctgacttg gttgatgctt attttgatgc
    13621 ttatgttgca accaaggaca acaatcttcg agctgatttg agcgccgcct tagcaacaac
    13681 agctaatcca tcaactctta agcgcattca gtacagctta aaggataagg atattattaa
    13741 gccacaggac ttagcagctt ggtacagctt tttgcttgat caggcctctg cacaagaaag
    13801 catttggcgt tgggctagag aaaattggaa gtggattaag gcttcactgg gtggtgatat
    13861 gagctttgac aagtttatta tttaccctgc taaccatttt aaaacagcag agcgtttagc
    13921 tgaatataag gccttctttg agccacagct tgatgatatg gcgattagtc gcaatatttc
    13981 gatggggata aatgaaattt cagctcgagt tgccctcatt gatagtgaaa aggaagctat
    14041 cgctaatgct ttaagtcagt actaatgata tcacaaagga gctggggacc atcctcaact
    14101 cctttattgg tgtcaaagct actatcttta agtaacattt agatcaaagg gtaattgctg
    14161 tagcttagtg gcactgcctg tcagcttttg gcaaatgagg aggcttcaat cataagcagt
    14221 ggttaatctt agcgccgtaa attactagtt gatcagagtc agagcttagg acggataggt
    14281 catagagaca attctttgtc tgtcagtttt ataacttaag taggtctcca gactaactgt
    14341 atgcttatga cctgtcatga gcaatagttt agcaaagctt aagctttttg tgttatcgtt
    14401 agattagaga attcatttag taaggtaatc cctaaagact acttgagcga ggctgttagt
    14461 ctttagagaa ttgaggtatc ataatgataa aactattatt agtagaagac gatttaagct
    14521 tgtcaaattc tatctttgat tttttagatg actttgctga tgtgacgcag gtttttgatg
    14581 gtgacgaagg actctatgag gcagaaagcg gtatttatga tttgattctg ttagatttga
    14641 tgctgcctga aaaggatggc tttcaagtgt taaaagcctt acgtgaaaaa gacatcaaaa
    14701 ttcccgtctt gatcatgact gccaaagaaa gcatcgatga caaagggcat ggctttgagc
    14761 ttggtgctga tgactattta accaagccct tttacctaga agaattaaaa atgcggattc
    14821 aggccttgct taagcgcgta ggaaagttta atgacaagag ccttaaattt ggcaacctga
    14881 ctgtagatac tacccgtaaa gaggtacagg tcaatgggca ggccatagag ctattaggca
    14941 aggagcttga tttactaatc tatatccttc aaaatcaaaa tgttattttg ccaaaatcac
    15001 aaatttttga tcgtatctgg ggctttgata gtgataccac tatctctgtt gtagaggtct
    15061 atgtctctaa aattcgtaag aagcttaagg ggacagactt tgttaatcat cttcaaacct
    15121 tgagaagtgt aggatatatc ttaaaagcta atgaataaac taaaaaaagg attattgtcc
    15181 gataattata cgcatttttt tcatttcttt gctattttta caggcatttt tgttgtcatg
    15241 accatcatta ttttacaaat catgaggttt agtgtctatt ccacagtaga cagcagtctc
    15301 atttcggtca gtcaaaatgc cagcaactat gctaatagga ccatggcgag aatatcttcc
    15361 ttttattttg atgcagaaaa taaccttatt caggctcttc ctgaactgga agcgtcaaaa
    15421 tcacttggct cctccaccac taatatggat attattttat ttagtgctaa tgggacgata
    15481 ttgaactcct ttgacgcttt ctctaattac caaagctttc gtttagacaa aagccagctc
    15541 aataacattg tcaccacaca gctgatgaat ttttatgggc aaaaggagaa ataccatacc
    15601 ctaaccgtta aggttcacat taaaaactat ccagcagtgg cttatatgat ggcagtggtt
    15661 aatgttcagc agctggatac tgctaatgag cgctatgaac agattattat catggttatg
    15721 attgtctttt ggttaatttc gattttggcc agtatttatt tggctaagtg gagcagaaag
    15781 ccaattatgg agagctatgc caagcaaaaa atgtttgtag aaaatgccag tcatgagctt
    15841 aggactcctt tagcggtgct gcaaaatcgt ttggaatcgc tgtttagaaa gcctaacgaa
    15901 accattttag acaatagcga gcatattgcg tcaagcctag atgaggttcg taatatgaga
    15961 atattaacaa ctaatctgtt aaatttagcc agaagtgatg atgggatcaa gccgcagcta
    16021 gttgatgttg atgcagcctt ttttgatact gtttttgaaa attatcaatt agttgcagaa
    16081 gagtcaggca agcagtttat ctcagttaat cagatcaata ggcccttaaa gacggataag
    16141 gctttgctca agcagctgat gaccattttg tttgataatg cgatcaaata cactgatcat
    16201 aacggtgtgg ttgaggtcaa ggttagaacg accgataagc atttattgat ttctgttatt
    16261 gataatggcc cagggatcaa ggatgatgat aagaaaaaga tttttgatcg cttttaccga
    16321 gtggataagg caagggcacg ccaaaaagga gggtttggac tcggattggc cttagcgcag
    16381 cagatcgtta cctcattaaa aggaacgatt accgtcagtg ataataagcc taccggcgcc
    16441 atctttgaag taaaattata gcactgagtt cttgctagcc cataatcagt atgaaaataa
    16501 cagtcactag atcaagaagt ctagtgactt tttttattgt cttctttttg ctgttgacca
    16561 agcagttgac aagaaaattc caatagatag tttaaagcca ataaaaccat tattaggctt
    16621 gcattacagg caggtatcaa acaaagatat agaaaaatat accataaaaa atctcataaa
    16681 agtgtcaaaa tggtaaaaaa ttgccaacaa tatgtcgata ttataccatt attatagtat
    16741 aatatttata atcgtatcat aatattaaaa tatctggtgt ctagctgttt ttgtaaaagc
    16801 aaaaaacttg caacacctta tgataaagca taaaggaata caagcatgat agtctaccta
    16861 aagcaacaca aaaattactg gaaattagtc agcatagccg ctttaatcat tattttagga
    16921 ggaatactaa caatgaattg gcttaatggc gaagagctaa aaaagaaaaa gtacagacaa
    16981 gagcaggata gggtagtgaa atacatagga gagcatatag agctatgtaa tggtcagcct
    17041 ataacaaaaa ttgagtttat agaatttcag ttagaaactg caaccaccgg aacttggtca
    17101 ataacaacaa ttgttaatga gaaatatctg attcattttt cagaagatag attaggtgaa
    17161 gaaatacgga cttcctatta ttctccaaaa gaatttaagc aatacagtga aaagatgagg
    17221 aataatatga ctaatgttga aacaatttat tacgaggaga aatgatgatt gatagagatt
    17281 ataaaaatat ttcagaggat gtgtataagg ttgattctgg taaagaaaga gatccgattc
    17341 aagaaggata tccggttgcc aatggaaaat accgcgttct tgaagccgaa gataaccccg
    17401 acaatggtat gcaggctatg gctgttgt
//
LOCUS       DARYVE010000046        17060 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYVE010000046 DARYVE010000000
VERSION     DARYVE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17060
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..971)
                     /locus_tag="TVW25_001426"
     CDS             complement(<1..971)
                     /locus_tag="TVW25_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1379048.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(1284..1724)
                     /locus_tag="TVW25_001427"
     CDS             complement(1284..1724)
                     /locus_tag="TVW25_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1379049.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(1721..2656)
                     /locus_tag="TVW25_001428"
     CDS             complement(1721..2656)
                     /locus_tag="TVW25_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1379050.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(3094..3507)
                     /locus_tag="TVW25_001429"
     CDS             complement(3094..3507)
                     /locus_tag="TVW25_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1379051.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(3605..4360)
                     /locus_tag="TVW25_001430"
     CDS             complement(3605..4360)
                     /locus_tag="TVW25_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1379052.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(4365..6860)
                     /gene="gyrA"
                     /locus_tag="TVW25_001431"
     CDS             complement(4365..6860)
                     /gene="gyrA"
                     /locus_tag="TVW25_001431"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1379053.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            7052..8035
                     /locus_tag="TVW25_001432"
     CDS             7052..8035
                     /locus_tag="TVW25_001432"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1379054.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(8240..9607)
                     /locus_tag="TVW25_001433"
     CDS             complement(8240..9607)
                     /locus_tag="TVW25_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1379055.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYDVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(9857..10459)
                     /locus_tag="TVW25_001434"
     CDS             complement(9857..10459)
                     /locus_tag="TVW25_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1379056.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(10460..11437)
                     /locus_tag="TVW25_001435"
     CDS             complement(10460..11437)
                     /locus_tag="TVW25_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1379057.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(11440..12699)
                     /locus_tag="TVW25_001436"
     CDS             complement(11440..12699)
                     /locus_tag="TVW25_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1379058.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(12711..13142)
                     /locus_tag="TVW25_001437"
     CDS             complement(12711..13142)
                     /locus_tag="TVW25_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1379059.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(13156..13749)
                     /locus_tag="TVW25_001438"
     CDS             complement(13156..13749)
                     /locus_tag="TVW25_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1379060.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(13721..14569)
                     /gene="prmC"
                     /locus_tag="TVW25_001439"
     CDS             complement(13721..14569)
                     /gene="prmC"
                     /locus_tag="TVW25_001439"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1379061.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(14566..15648)
                     /gene="prfA"
                     /locus_tag="TVW25_001440"
     CDS             complement(14566..15648)
                     /gene="prfA"
                     /locus_tag="TVW25_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1379062.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(15690..16259)
                     /locus_tag="TVW25_001441"
     CDS             complement(15690..16259)
                     /locus_tag="TVW25_001441"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1379063.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            16446..16631
                     /locus_tag="TVW25_001442"
     CDS             16446..16631
                     /locus_tag="TVW25_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1379064.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            16686..>17060
                     /locus_tag="TVW25_001443"
     CDS             16686..>17060
                     /locus_tag="TVW25_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1379065.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         4797 a         3748 c         3261 g         5254 t
ORIGIN      
        1 cagttaccca ttaggctgtc aatcaatcct ctaaagaaat caataatttg ctgaaggatt
       61 ccctgtccag tctttaaggc ttcagtagca tcaaagttca cgttgatatt tttaaaggta
      121 gatccggcct tttcaacaat actatccttt aaagcattca gcgttttggt gaagttttca
      181 ttggaaatca cgccactatt tgagaggtta agcgcgaaat tgataataag gttaatctga
      241 tcaggtgtta ctgccttggt taacccataa tgatctaagg tttctgttac aatttggcgc
      301 accttttcct cattaacccc ttctccagcc tttgcgacag cagctttaat atcagtaagc
      361 gcaacattta gcttatctgc atcatagcct gttttacctg cattttcggt attgatatta
      421 gatagggttg atagctcctc ttgtgccagc ttcttgtttt cctctgggac tttggcacca
      481 tttttttcga gtgaataata aataccggct aaagctgatt ctccagtaac tgggattggt
      541 gcagctacag taatattggc atgctcaatg cccaaggtca cagcggcgtt acgatacata
      601 tcttgcgtca ccttagtgat attttcaggt gttacaatag ttaccttaag cgtttcttta
      661 gctcccagct tttgaatcct aactgaggaa taaagctgta ggctcggatc atctgctaca
      721 ttcatgatac tagcataggc agttgtattt agggtgctta atttgttatc agaagcacta
      781 ttgtagtgaa gcaaggccaa ggtttgctct ctttgctcag cagacagtga atagcctaaa
      841 acgtaatcag gctgaacata ggtttcatca attacctgtt gaacattatt agctgcagcg
      901 tgtactgttt gaagcataaa taccgaagcc aaagccatac tggctgctat taatttcttt
      961 tgataagtca tttttctacc tcttttgtgt tataaatttt cctttacgag aatcctccag
     1021 aaaagacgat taaagccaaa gtatctaggt gcctagtaag accgttttac ttagctctgc
     1081 aaagggcaat attcctagtc tttttcaaaa tctaacgcct ctattgtagc atttttacct
     1141 caataagacg attaaaaagc tgaaacaaag catagctaga atggccaagc actattttta
     1201 caacaaaaaa actagtgcat aatggcagct tagatgtagc tactatcact agtccaatga
     1261 ttatcttatg cagcaaccag tctttatgat ctgaggtttt cttgatggtt attgtccttt
     1321 aaatagaaat aataatgatc atcagttttg atgacatagc catttttaac ctcattaatc
     1381 acgtcctttt gatcaaactg gtagtcctta ggcggtaata actctgagga aaaaaggcta
     1441 tcataaggca cctcaccatt gtaaaaatgg taatggtcac catgagaggt aacaaaacca
     1501 tcatccgaga tagacacaat aatttgctct gctgctatcc cctcttcctt gctaacttca
     1561 ttaggacttt tgtcagtctc tttctttaag gctttgcacc ttttttccaa ttgatgagat
     1621 gattttagct tcttgcctgt gctatcttgg gctttaaagt cacaagcgga caaaggaaat
     1681 aatagtaaga tagtgaataa cgataaataa gcttttttgg tcatgtttca ctctccaata
     1741 cacgatatag tgtttctaaa ttcattttta aatgctctag ataagttttt tgatcagctg
     1801 gaaccacctc aagcgggctt aggatatcaa ttgctacacc gttactttga gccaaggttt
     1861 tggctagctt atctgaagca ttttcttcga cgaaaatcgt cttcacatca tattttttga
     1921 taaagcggtc aatttgagct aattggcgag gactaggctc ttgctcagga gatatccctg
     1981 caattcccaa ttgctttaga tcaaatctct tagctaggta ggaaaaggct gtatgctgtg
     2041 tcacaaaggt tttcctacct agagattcaa acttttcctt ataggtcttc actaattttt
     2101 gagccttagc cttaaaacgc ttagcatttt gcaaataaac tgccttgtga gcaggatctt
     2161 tttgactcaa taaagctgca atctgctctg cctcttgact agctaagata ggatcagtcc
     2221 aagtgtgagg atcatacaag gcatcggtat tcattccttt ttttatggtg aagtgctcca
     2281 agccttgaac cttgtctaat gttagatgtg atgtcccctc catgactgct aatccctttt
     2341 tttccagctg tggtgccaaa tccgcagccc aagcttctaa tatcttggaa tggtaaataa
     2401 agacatctcc atcgtaaacc ttagcaacaa ctgtcggact tggctcatac gagtgtatgc
     2461 tagtgttttg ggcaatgacc tgaacatcat ttaaatcccc gcaaatctcc tttgtcatag
     2521 cataaatagg ataaaagctt gtttttatga ccaaaccggc cttcctactg ctagagctct
     2581 gatgacaggc tgatagaccc aaaagtactg ctaatagtcc tactgcgaca attgttttct
     2641 tgaatcctct aatcatatct actctcttaa ctagttaatg acctaaaaag gataccatga
     2701 tttaactgaa atgtcaatat tttatcattt tagcgcacga cgtacacgca tgaagaaaat
     2761 gcatgtaagc cttttttagc cccatgcatt ttttaatcta tttctagcgt tttgacattg
     2821 caatatcatc agtttgtcaa tttcaatgtg atgacttcat cacattttgc taaaaaggcc
     2881 atagtgatga taaaaaaccg ctaccagaaa gcgtaaatgt cttcttgctt ttgtcgtgat
     2941 tttagtgaac cgcctaccaa ctgaactgat gctggcttaa ccatttcctg gccaccatca
     3001 aaagcctgcc tctcaattaa caagcttact caaggaagag gtgactgagc catgcatccg
     3061 tcttagttat gactaacagc ttatcttggc atttcattca tgtaattcca gtggcaggcc
     3121 atcaggatca aaaaagaagg tcatcttctt accagtataa tcatcatacc taagaggctc
     3181 gacagcaatg cccttagcca ttaattgttc aatataagct tcaataggct taacatgaaa
     3241 agctaaatga cgaagcccac aggcctcttt gtcatattcg ggcctaccga tacgcttagg
     3301 cggtgcctga taagctggat cagtcttttt attgccaaaa atctctaatt caatggctcc
     3361 acattttaaa tccaatttgt aatcatgtct atcaggccgg tgattttcac gaataatctc
     3421 aaagccaagc ttattgacat aaaaatcctt agagacctca taatccgaaa caatgatagc
     3481 aatatgatga atagccttaa gctccatatg atttagttcc tttattaaat aaaaaaagtg
     3541 aaacaaagca atgccaagat tactttgttt cacccctcgt agcgacccct cgcctagatt
     3601 aggcttaggt tgacatctga ttgtaagagt gattaaaggc cttcaaaaca tcgtcaggtg
     3661 ctttgttaaa ctcatactcg tttttgattg ctcctttgac aatgattcgc tctgttgcct
     3721 cataatccgt acaggtgacc aaggttacct cctttagccc tggtgtgtca ttgataacat
     3781 ctattctctc aggtgtgacc gtaaagacgg cattgatctc gtactcgtaa atacgctcct
     3841 tatctgtaag gtaaatagac atcccttctt ttgctctttc aagcggtgag aataacattt
     3901 cagaagagcc tgttagtcca aaaatatgat gactggctaa ggagtaattg ttttctcctc
     3961 ccataacctg gtcctctttc atggtaccag caccgtatat aagctctgtg ttgccaagcc
     4021 ctttaaagat tggtaggtta ataccaagct ctggtatggc aatacctcct attactggaa
     4081 gctgctgggc gtccatttga gcctgtaaga cactttcggt gctaactggc tgaactgctt
     4141 gaaaatcaaa gcttgacttt gcttccttat tctttttaat cgtctttttt gaaacctttg
     4201 taacttgata tttattagaa ttccaagcaa tcagggtgtt tctaatgggc ttgttaaata
     4261 acaaggctaa gcctatgatt aacaataaga cgactagaat acctctagca aaggacatct
     4321 ttcttcgttt ttgtcttctc ctgtgggttc tttttgccat tcatttactc cttgctagaa
     4381 tttattggtg cttctgttaa agctgtatca gtctgagcga ttgctgttgg atcgttgtct
     4441 tcagcctgta ccaaggtaaa ggtaacaatc ttagaatctg tatctagcct cataacctta
     4501 acaccaagtg ttgaacggcc agtctgagaa atacttgaaa cattggtacg aataatcaca
     4561 cccttcgttg tgatcaccat aatatcctca ctgccatcaa cagtcatcag gccagccaac
     4621 tggccatttt ttgcggtgat attagctgtt ttgattcctt ttccacctcg acccttagtt
     4681 gggtattcgg ctgcactggt acgcttacca tagccatttt cggtgatgac taagacctct
     4741 tgcttgtcat tgatacgaga agctccgaca acccaatctt cctcacgaag cttgacacca
     4801 cgaacacccg tagcgctacg ccccatgcct cgaatggtag cttcattaaa gcgaacagaa
     4861 taacctgatc ttgttccaat gataatatct tcctgaccat ttgtcaagag aacattaatc
     4921 agctcatctc cttccttgag attaagggct cgtagaccat tctgacgaat attgctaaac
     4981 tctgatacct cagttcgttt gacaatccct tgctttgttg taaagaagaa atatttatca
     5041 agaatgtctt cttttttagc attgataatt gtttgaatgg tttcaccatc atctagcttt
     5101 agtagattga taacaggaag tccttttgca gcacgtccat attctggaat ctcataggcc
     5161 tttaagcgat agacgcgccc aaaattggta aagaaaagca atgtgtcatg tgtacttgtt
     5221 gagacaagct cacgaacaaa gtcatcgtca ttgacacctg ttccctgtac accacgacca
     5281 ccacgctttt gagatcgaaa ctcgtcttga gcaaggcgct taatgtagcc attgtttgat
     5341 agggtgatca aaacatcttc ttcctcgatc aaatcctcat cttctaatga caatacctca
     5401 ccaatcatca attctgtgcg gcgaggatta gcgtacttgc gcttgatctc ctccatttct
     5461 tccttgatga tggcttcgat acgctctggc cttgccaaaa tatctgccaa atctgcaatc
     5521 aaagccagta ggtcatcgta ttctgattga attttatcac gttccaagcc ggtcaaacgg
     5581 cgaagacgca tgtctaaaat agcctgactt tggcgttcag acaagtcaaa acgagacatc
     5641 aattctgctt gtgcgataat atctgtctcg ctattgcgga taatggcaat aacctcatct
     5701 agatggtcaa gagcgataag taagccctct aaaatgtgtg ccctagcttc tgccttgtcc
     5761 ttgtcaaatt gagtcctgcg tgtaatgacg tccttttgat gtagaatata attatcaata
     5821 atctgtctca gtgacaagat tttaggaatc ccgccttcaa tggctagcat attgaagcta
     5881 aagtttgtct ggagacttgt caatttgaat aggttattta aaatcacatt agcagatgca
     5941 tcgcgacgga cttcaatgac aaatcgtacc ccttgtcggc ttgattcgtc acgaacagct
     6001 gtaatgccct caatacgctt ttcttgggct aagcgaacaa tatgctcatg gacctttgtt
     6061 ttattaatgc cataagggaa ttctgtgacg acaatccgct cccgtcctgt actagtggtt
     6121 tcaatctcgg tgcgtgaacg caaaacgatt gatcccttac cagtctcata agccttatga
     6181 attcctgaac gtcccatcac caaggcacct gtaggaaaat ccggccctgg aagaacctcc
     6241 attaaatctc tggtagtgca gtcaggattt tccatgacca tcttaacagc gtctatggcc
     6301 tcagctaaat tatgaggtgg aatattggta gccataccaa ctgcgattcc ggtggcacca
     6361 ttgaccaata aattggggaa gcgagccggt aagactaagg gttctctttc attaccatcg
     6421 tagttatcct gaaagtcaac agtattttta ttaatatcct ttaagagctc tagcgcgatt
     6481 ttgctcatac gagcctcagt ataacgctga gccgcagcac cgtcaccgtc catagaacca
     6541 aagtttccat gaccatcgac aagcatgtga cgatagctcc accactgggc catacggacc
     6601 atcgcttcat agatggacga atccccatgt gggtggtact tacccatgac atcaccggta
     6661 atacgagcag attttttatg tggcttatca ggtgtgacgc ctagctcatt catgccataa
     6721 aggatacgac gatgaacagg ctttaagcca tctcgtacat ctggaagtgc tcttgctaca
     6781 ataacgctca tagcataatc aatgaaactc gttttcatct cacttgtcag attgacgtca
     6841 actaaatgtt tatcttgcat ttaaggaatg ctccttttct agtcaatact cttttaatta
     6901 taccataaaa tccttatttt ttctgattgg aaacgctgtc cgaaaacaat tttcataatt
     6961 tggtcgaata tcatgacaaa gacattaaaa tgtgttaaaa taagatcgta tgagcaattt
     7021 gctctaacta aaatgaagga gatgtttaga aatgactgca actaaacaac ataaaaaagt
     7081 catcttggtt ggcgatggtg ctgtaggctc ttcttatgcc tttgcactag taacccaaaa
     7141 tattgcccaa gagcttggta ttattgatat ttttaaagaa aaaactcaag gagatgctga
     7201 ggatttaagc catgcgcttg cctttacctc ccctaaaaag atctatgctg ctgattatgc
     7261 tgactgtcac gatgctgacc tagttgtttt aacagctggc gctcctcaaa agccaggtga
     7321 gactcgtctt gaccttgttg agaaaaatct acgtattaat aaagaagtgg ttactcaaat
     7381 tgtggcctca ggctttaagg gaattttcct tgttgctgct aatccggtgg atattttgac
     7441 ctattcaacc tggaaattct caggtttccc taaggaacgc gttatcggtt ctggaacatc
     7501 acttgactca gcacgcttcc gtcaggcact tgctgccaaa attggtgtag acgcacgttc
     7561 tgttcatgcc tacatcatgg gtgagcatgg agattcagaa tttgctgttt ggtcacatgc
     7621 taatgttgca ggggttggat tgtacgactg gcttcaagct aatcgtgacg ttgatgaaca
     7681 aggcttggta gacctcttta tctctgtacg tgacgcagct tactctatca tcaataaaaa
     7741 gggtgctacc ttctatggta ttgcagtcgc cctagcacgt attacaaaag ctatccttga
     7801 tgatgaaaat gcagttcttc cactttctgt tttccaagaa ggccaatacg aaggcgttga
     7861 ggattgctat atcggtcagc ctgctattgt tggtgcctat ggtattgttc gtccagtcaa
     7921 tatcccattg aatgacgctg agcttcaaaa aatgcaagct tcagcaaacc aattgaagac
     7981 tattatcgac gaagccttct ctaaagaaga gtttgcgtct gctgctaaaa actaattaaa
     8041 aaatgaatgt gttagatctt gctctaacgt tttggaatca ctacaaaaag cctaatccaa
     8101 tcggataggc ttttttcatg cgtctaacag cgaggtgcaa gacaaagcac gctttcatta
     8161 agcatcgtgt gtgctatgct tatagtctta agtcacaaaa aagacaacca gctttatgag
     8221 ctggctgctt attagcttgt tattcagcac caagtgctgc cattgtaatg tagttatatg
     8281 gcttgttaaa gtgcggtaag aagaaaatat cagtcaaagc taatttctca atggtcactc
     8341 cttcttggat agcaagtgag aacatatgaa ttcccattga aatatcttca tgtgaggcca
     8401 tttgagcacc tagaatacga cgtgattctt tatcgtagac aatcttaatg gttacttgga
     8461 agttaccatg ctcgataaat tctggttttt gattgtcagt gtattctgtt actgctgcat
     8521 caaagccaag gcattttgct ttctcaagag ttaagccagt tgataccatg tgcaagccgt
     8581 agatagagat accatttgat ccctgcacac caataccctc aagagctgtg ccacaagcgt
     8641 tatgagctgc gacaatccct gtacgaacag catttgaagc aagggcaata taattggtat
     8701 cgcgagttgc gttgtcatag atggttgcac aatcaccgat tgcataaatc cctggaatag
     8761 atgtttcttg gtgtttgtta acaaggaagg caccattacg gaaaagctca atcttgccag
     8821 caccaagagc tgtatttgga cggaagccaa ctgcaaggat aaccatatca acatcatatt
     8881 cattcttatc agtgattagc ttttcaacct tgccatcacc agcaacctct ttgacagttt
     8941 ccccaaaggc caactgaata ccatgctctt ctaggttttt agacatgaca tctgtcaaat
     9001 cacgatcata gtagcctgct agacaagtat ccgcaacatc aatcagaata acctctttgc
     9061 ccttacgttg gaaggcttct gcaagctcta caccaatgta gcctgcacca acgactgcaa
     9121 cgcgcttaat gtctttgttt tctaatttcg aaatgacatc tgctgaattt tggtacaatt
     9181 taacgaattg aagattttca agtgttgctt caaactctaa tgagccctct ttgatttctg
     9241 cacctttaat tggtggcaag ataggctgtg aaccagttgc aaaaattaat ttgtcatatg
     9301 actcaacatg ctctttgcca tcaacaaggg ctgtcactgt tttagcatcg tagtcaatag
     9361 attgaactgg tgattccatg taaaccttag caccaaggga ctctagctct tccttatttg
     9421 agtagaataa gccctctggg ccagaaattt gttcgccaat ccaaagtgcc ataccacagc
     9481 ctaagaatga aatatttgag ttttggtcaa atacaacaat ctcattagca tcaccatagt
     9541 ttgttaacat agtcttgata catgccgtac ctgcgtggtt tgcaccgata acaacgattt
     9601 tactcatatg attatgttcc tcatttcaca atttatatta ggtctctatt ataacacagg
     9661 gaaaaagcgc ttccaactaa aatgctcatt tttcttgctt ttttataccg ttttttagtc
     9721 aataaataag acagcctatc atttgttgaa gggtcgtaca aagaccggtt tgcttcagtt
     9781 aagtcaagac gacattctta ttcaactatt ttcccaaatt cattacatga ttaagaccat
     9841 tttttgtcgt taacttctaa aaaagactca taagctcaat caggtaaaga ttgacatgta
     9901 cctcttgagc ataataaata ttgccgccgt tgcaataaag ctttccacca gagaggaggg
     9961 ctaaggggtg gtaataaaaa taggtttttc cagtagtatt tcctaggctg ggtgcaacga
    10021 cagttctaga atagttagtg gctagttcaa ttgtatgctg accgccattt ttagcaacgt
    10081 aatcaatata ggcggttcca aaattgtaag cttgaacagc tgtccaaggg tctacgccgg
    10141 ctttttctgc taaagctaaa ttgtgagata gcaatctgac accatactca atgctagatt
    10201 gactatcggt gatcgaatcc cttatgccag agctgctttc gcttgactgc ataacgtcag
    10261 cttctcctcc cttagtttcc gtgtatatca tggctagtac cagatcgacg tctgctttgt
    10321 taccgttttc tgctaaaata cgctctactg ttggcttgta ttgtaggact ctgtgcacat
    10381 tcttatgaat ggtaactgct tcgtacaggc aaaaaatgag gacggctaat cctaagatac
    10441 gctttaacac tctaaacatt tagttatttt tgatatcctc tatatttttt atcaatatgg
    10501 aataggttcc gttgtcattc aagataaact ctactgactc agcatcttga taaactgcat
    10561 tagggacaag aagctcaatt ccatttgaca gcgacagctt ttgcgtctct agctttttta
    10621 gctgtctaga atgatcaata tcactgacct gaattggttc gggaatcatt tccttgacct
    10681 gatccacaaa ggttaacctt gcagtcaggt tctggtcaaa taattgatct gctagctttt
    10741 ctggagatag agctgtttct tcttctagat ttttagccag tgctactttc atctttgatt
    10801 gaaaagcaaa gtcatcttgg ttaaaattct cggcaacctt ttgagcggtc tgctcaagca
    10861 tttgaataga ttttttgaca gattgctcag gtgttacctt tagcagcttc tcagaaaagt
    10921 aatgagcaaa gcttccattg tgcttcatgc gtttttcgat taagtagtaa tagcctgttt
    10981 gacggttaat gaccaaggct tcatcaggtg cctgagtagg gcttggcaaa ttattttgcg
    11041 tgatcgtaat aggattttca tgatcgtctg atagatgggc aaaatgctct tttagggcaa
    11101 tgcgtaaaaa ggccagataa ggcactcctt ccttatcaaa ctgaataaaa accaaatcgt
    11161 ttgtcttttg atgttcagaa gcgacaaatt cttccttcca aagcttggca attgttactg
    11221 atgtttccaa aagctctgta ccgattgtgg taaaaaaagc atgatcagct tctaattgcc
    11281 cacgtttagc gtcgtcagaa aaaaccttgg ctaatttttt gcgaaaatac tcatcaattc
    11341 ttggtgttat agctactaaa gcatctgata agatcagctc ggtatcgttt ggtgtgaatt
    11401 ggtggatcac aattcctttt atataaatat ctagcattgt tagttcttct tgtataatgg
    11461 gaaggcgtca gtcaatcggc gaacctcata acggacctct tcaaggattt caggctgctg
    11521 gtggttaacc aaggccttga taattaaatg agcaatagtc ctactttcgt ctactcccat
    11581 tccacgactg gtaatggcag cgcagcctat gcgaatgcct gatgttttaa agggagatag
    11641 ggtctcaaaa ggaatagcat ttttgttaag ggtaatatta acctcatcaa gcaaggcttg
    11701 agcaagcttg ccattttcaa tcaccttagt cacatcaaca aggaaaagat ggttatctgt
    11761 accgcctgag atcagacgaa aacgatcatc cttggcaaaa acctctgcca ttgctgctgt
    11821 atttgctata acagcccttg catagtctgt aaaggcagga tcaagcgcct ccttaaacgc
    11881 aacagccttc gctgctatga catgctccaa aggcccaccc tgtagaccag ggaaaatagc
    11941 tgcattcatt ttccttgaaa ttgcttcatc atttgtcaaa agcaggccac cacgaggacc
    12001 acgaagggtt ttatgagtgg ttgaggtcac aatatgagca taaggtactg gattttgatg
    12061 cagacctgct gcaaccaagc ctgcaatgtg tgccatatcc accatcaaat aggatcccac
    12121 ctggtctgca ataaaacgaa attgctcaaa atcaatctgc cgagaatagg ctgaggcacc
    12181 tgcaacaatc aacttaggct gaacagcctt agcttgcttt aggatagctg cgtagtccag
    12241 cttttcagtt tccttatcga cagtgtagcc gacaaattga taggtttttc cagaaaaatt
    12301 gacaggtgag ccatgtgtca agtgacctcc agctgccaaa tccataccaa gcacagtgtc
    12361 accagcatta atcagtgcca tataagcagc agcattggcc tgactaccag aatgaggctg
    12421 aacgttggca taggctgcac caaagagctt tttggcacgc tcaatagcaa ggctttcaac
    12481 aatatcaaca tactctgtgc cgccataata acgcttgctt ggatagccct cagcgtattt
    12541 gttggtcaag acagagcctt gtgcttgcat aacagccttt gagaccatat tttcagaagc
    12601 aattagctca atattatgct cttgcctgtc ctcctcggcc tgaatagcct cccaaagctc
    12661 ctgatcatag tctttgtagt tctcgttgtt aaacatcatt attgtctcct ctataatagc
    12721 ttcataaatc gtaattgtgt cttatcatct acatagctca gcttacggta aaaggcatgt
    12781 gcctcggtcc tgtgactagc agaattaagc cgaataaagc ttactttctc ctgcttagcc
    12841 ttctcctcta aagcagctag taagcgacga ccgatacctc taccttgatg gtccagcctc
    12901 actgctaagg ccaaaatatt aaagcctttt tccgagtaaa gcgactcgta gcattcagca
    12961 tgcagatagc ctaagagcag attggtctta gtatcagcat agcccagcaa ataatgatgc
    13021 ttatcggatc ttagtttttc caattggctt tttgtcaatt caagagaaac cttgtacccc
    13081 aaggattgat cattaatgtc acaaatagct tgacaatctg tttgatctag tggtcttagc
    13141 atagccttac ctcctctaaa atggcagctc tggaacctta gctaataatt gctccttagt
    13201 aatagcacct tgtcgtaaaa tactgacctt aggtgacgat aaatccaaaa tagtagaatc
    13261 cttccctgtc aaataggcat catcagcata accatcaacc tttccatcaa atgccttgac
    13321 aatgtcatta aagcattttc cactctttga gcctgacagg ttagcagatg gcccaatcaa
    13381 gggacccgtt gctctgataa ttttagctgt gagagggtga ctgggtagtc gaaagccaac
    13441 tgtttttagc ccagaattaa tccaataggg tgtctgggca ttggctttta ggataatcgt
    13501 aagtggacca ggtaaaaaag cctcgtacag cttgttaaga taggcaggct gctgcttaga
    13561 aaaagccaaa atactctcaa aatcagccac attaaggttc atagccttgt cgcgaggcct
    13621 ttttttgaga cgataaacag cattaacagc ctcttcattt aaggcctgag caaaaagacc
    13681 ataaactgtc tcagttggta aaataagagc tccaccagcc ttaattgtct ctatcaaatg
    13741 tgttatcatc aacaaccacc attctttctt tacccagcat atccttaagc actctgatac
    13801 gcttttgagg gaaacgcttg gataagagcc tttttaagcc ttctccctgc ttgtagccta
    13861 tttcaaaata gagcttacca cttgtcgtca gataagcact agcttgttcg ataatgcgtc
    13921 ggtaaataga aaagccattt tctgcagcaa ataaggccaa atgcggctca gattgataaa
    13981 cattcaagcc aacctcgtcc ttatcctcat aggcaatata gggagggtta gaaacaatga
    14041 tgtcaaactg ccctgatagc ttgctaaaaa ggtctgactg ctcaaaggct atctctacat
    14101 gatgatctaa agcgtttgag taagcaaggc tcaaggcatc agctgaaata tcagaggctg
    14161 tgacctgcca gttaggtctt gcttttttta aagcaattgc aatagcacca ctgcctgttc
    14221 caatgtctaa aacggatttg cgagtagcgt cattttcctt caagataagc tcaactaatt
    14281 cttccgtctc tggtcttggg attagcacgc gcgaatccac tgcaagcacc agatctctaa
    14341 aataagccct gcctgtgata tattgtggcg atacatgctg gctaagcgct aaaaaaatcc
    14401 gctctaataa ggcttgatcc tctgaagtga cctcttgatt ttgatgaagc aaaaagtcaa
    14461 ggcttgtcca ctgctttaat tctttaaaaa cataggcgag gttttcacga tcctcaccta
    14521 tgttttctag cctgtcttcg taggctctta gttgcttagc atagttcatt ggttatttag
    14581 cgattctaat ttctgagttt gatcatatag cactaaagcg tcaacaatct cgtctaactt
    14641 tccagacaaa atggtgtcta atttttgcag ggttagaccg atacggtgat ctgtcacacg
    14701 attttgtggg aaattatagg tccgaatccg ttcagaacga tcacccgtac cgatagttga
    14761 tttacgctct gcgtcctgct cgtcctgtgc gatctgtgca aaatgatctg ctacacgtgc
    14821 ccgaataatc ttcatagcct tgtcacgatt cttttgctgc gttctttcct cttgcatctc
    14881 aaccttgatg tttgttggga gatggacgat acgaacagcg gttgccacct tgttgacatt
    14941 ttgtccgcca gcaccagaag catggtaaat atcaatacga aggtcctttg gatcaatgtc
    15001 gtactcaact tcttctacct ctggcatgac taagacagtc gcagttgaag tatgcacgcg
    15061 cccttggctt tctgttacag gaacacgctg tacgcgatga gcacctgatt cgtattttag
    15121 cttggaataa acagattgtc ctgaaaccat agcaacaacc tctttaatcc ctccaacacc
    15181 attataggaa gcctccatta cctcaaagcg ccagccttgg ctttcggcaa atttttggta
    15241 catggctaag agatcaccgg caaatagagc agcctcatca ccacctgcgg caccacgaat
    15301 ttccaagata atatttttat catcatttgg atctttggga agcagcaaaa gctttaactt
    15361 gtcctcatag gcttccttgg cagacttggc ctcttttagc tcctccttgg ccatctcttc
    15421 aatgtcagga tcgccgccgg cttccttaat catctcctca gcgtcatcaa tggattggat
    15481 aatagcctta tactgacgat aagctgctac tgtttctcgt gtgctagcct cttcctttga
    15541 cagagccata aaacgtttgg tgtcagaaac aacctccgga tcacttaata attcgcctaa
    15601 ttcttcataa cggtcctcaa cggcctgtaa ttgatcataa atattcatta gggggtattc
    15661 tctcctcttt ttacttgttt tagttgttat tagattggtg ggtgaaaata atgcttgcga
    15721 caaactggaa tataggtctc attgccacca atttgaatct gtgctccctc ataaacgggc
    15781 ttaccatgtt ctgttcgcaa taccatagtt gcttttttgc tgcaatattg acagatggtt
    15841 tttatctcat caatcttatc agctaacagt aacaggtatt tggagccttc aaacaattca
    15901 ttttgaaaat cattttttaa gccaaaggcc atcactggaa catttagctc atcaaccaca
    15961 cgtgctaaat catagacatt ttgcttgctt aaaaattgac attcgtcaat caagacgcaa
    16021 tagggcttct cctgcaattc agcaataaat gcaaaaatat ccatatcatt cgaaattggt
    16081 acagcctcac gacgcatgcc aatccgacta gaaacaatgc caaagccatc acgtgtgtct
    16141 agcgcacttg tcataatcac aacaggcttc ccctgttctt cataattgtg tgctaccttc
    16201 aagatttcaa tggtctttcc tgaattcatt gttccatatt tgtaatataa ttgagccaaa
    16261 atggagattc ctaccttctt cttttgtcct acttattcta tcatatttgt ccctatttgg
    16321 cgattgcctt atctgaaaat cttattttca caacagctaa atcctgtgct gttgagctaa
    16381 ggttaggctt tttgaagctg acatgctaca atagaggtat cattaaaaaa aggagattga
    16441 ctattatgcc atttgtaacg attgacctgt ttgaggggcg tagccaagaa caaaaaattg
    16501 ccctagcgcg tgaggtgaca gaggttgttt ctcgtatcgc acaggctcca aaagaagcga
    16561 ttcatgttgt aatcaatgac atgcctgagg ggacctattt cccgcatggt gagatgaaaa
    16621 ccaaagccta atgcctaagt cccacttatc taggtgggct tttcctattt gaaaaggagg
    16681 gcctgatgat agctactgat cagatcaaga tgatgggaac aatcattgat atttgcattg
    16741 actcatcaaa agcaaagcag caagcagcta ctatccgaga gctactaacc ctttacaatc
    16801 accgtttttc ggccagtgac gacagctctg aattaatggc aatcaaccat atggcaggta
    16861 ttcagccagt gcgtgtgcat tcagatttgt ttgacttaat ctcaatcgga aaagagcata
    16921 gcttggctta tccaagcaac cttaatatca cacttggtcc tttagtgcaa agctggcgca
    16981 tcggcttttc agacgctaag cttccagatg aagcaactat tgatcgcaga ctaagactaa
    17041 ccaatcctaa tcatatcatc
//
LOCUS       DARYVE010000047        16841 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYVE010000047 DARYVE010000000
VERSION     DARYVE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16841
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            29..739
                     /locus_tag="TVW25_001444"
     CDS             29..739
                     /locus_tag="TVW25_001444"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1379066.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            918..4658
                     /locus_tag="TVW25_001445"
     CDS             918..4658
                     /locus_tag="TVW25_001445"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1379067.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAENLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            4777..6234
                     /locus_tag="TVW25_001446"
     CDS             4777..6234
                     /locus_tag="TVW25_001446"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1379068.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            6291..7313
                     /locus_tag="TVW25_001447"
     CDS             6291..7313
                     /locus_tag="TVW25_001447"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1379069.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            7310..7867
                     /gene="purN"
                     /locus_tag="TVW25_001448"
     CDS             7310..7867
                     /gene="purN"
                     /locus_tag="TVW25_001448"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1379070.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            8014..9561
                     /gene="purH"
                     /locus_tag="TVW25_001449"
     CDS             8014..9561
                     /gene="purH"
                     /locus_tag="TVW25_001449"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1379071.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(9939..11093)
                     /locus_tag="TVW25_001450"
     CDS             complement(9939..11093)
                     /locus_tag="TVW25_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1379072.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            11484..12746
                     /gene="purD"
                     /locus_tag="TVW25_001451"
     CDS             11484..12746
                     /gene="purD"
                     /locus_tag="TVW25_001451"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1379073.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            12975..13463
                     /gene="purE"
                     /locus_tag="TVW25_001452"
     CDS             12975..13463
                     /gene="purE"
                     /locus_tag="TVW25_001452"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1379074.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            13450..14523
                     /gene="purK"
                     /locus_tag="TVW25_001453"
     CDS             13450..14523
                     /gene="purK"
                     /locus_tag="TVW25_001453"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1379075.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            14538..14762
                     /locus_tag="TVW25_001454"
     CDS             14538..14762
                     /locus_tag="TVW25_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1379076.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            15359..16651
                     /gene="purB"
                     /locus_tag="TVW25_001455"
     CDS             15359..16651
                     /gene="purB"
                     /locus_tag="TVW25_001455"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1379077.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
BASE COUNT         4656 a         3253 c         4127 g         4805 t
ORIGIN      
        1 ttaaatgcaa agaaaggcga acaaataagt gtctaatcaa ctcatttatt caggtaaggc
       61 aaaggatatc tatgaaacag ccgatgacgg gattgtctta atctcctaca aggatcaggt
      121 cactatgcta aatggagcac ataaggaaat gattgaagga aaagggagcc ttaataatca
      181 gatttctgcc ttaatctttg ataggctaaa tagggttggc gtatcaactc attttattaa
      241 gcaattatcc gagacagaac agttaaataa aagggttgcg attattcctt tggaggttgt
      301 tttacgaaac gtggccgctg gctcattttc aaagcgcttt ggtgttaaag aaggtcaggc
      361 tttggacgag ccaattattg agctttatta caagaatgac gctttagatg atcctttcat
      421 taatgatgag catgtcagct ttttaaagct tgcgactgat gagcagatag cctacatcaa
      481 acaagagacg catcgtatta atgcttattt gaaggagtgg tttgctagtg ttgggttgac
      541 actggttgat tttaagctag aatttggctt tgataaggag gggatgctta tccttgctga
      601 tgagttttct ccggataatt gccgcttgtg ggataatgcg ggccgtcaca tggataagga
      661 cgtttttcgt cgtcagcttg gcagtttgac gcaagcctat gagactgttt tagaaaggct
      721 aagagcattg gatcaataaa gaccagctta tttgttgtca gttaagaaag ggagctcttt
      781 tttgtccgtc atgtaagaaa ataaatcagt tcagactatt tgagctgctg tctaagaaag
      841 gctgtctgct attggagaaa agagtcaggc tagttcttat tttgggctgg tttctgattg
      901 gacttggtat attaactatg aataaacgta tttttgttga aaagaaggct gattttcaga
      961 ttaaggcaca ggtcctgtta aaggaattga aacatcagct gcagttaaag acactggttg
     1021 atttgcgtat tgtgcaggtt tatgatgtgt ttcatttgga tcaggagctg cttttaacag
     1081 ctataaagca tgttttctct gagcaggtca ctgatcaggt attgtcagaa gaagctttac
     1141 aagcagattt aaaaaggtat gccttttttg cgattgaagc tctgcctgga cagtttgatc
     1201 agcgtgcggc aagctctcag gaagccttat tgttgttagg agcctcaact gatgtgactg
     1261 ttttgacctc acagctttat ttggtcaatc aagacattgc tgctgaagaa ttagaagcct
     1321 taaagcagta cttgttaaat ccagtggatt ctaggtttaa ggacatatta gccggtcttg
     1381 atgatcagga tttttcagta gcagataaag tgattccaac gcttgatgtt tttaatgatt
     1441 atacagcgga aaatcttgct cgttacaggt ctgagcaggg cctagcaatg gaagtggagg
     1501 atctgctgtt tattcaggat tatttcaaga caaaggggcg agtgccaaca gagactgaac
     1561 taagggtttt ggatacgtat tggtctgatc attgtcgtca cacaaccttt gaaacagagc
     1621 taaaaacgct tgatttttca gcttctcatt ttgaaaagca gctccaagct acctatgaga
     1681 cctaccttgc tatgcgtgat gagctaggtc gatctgaaag gcctcaaacg cttatggata
     1741 tggctaccat ttttggacgt tatgaaagag ctaatggtcg tttagaggat ttggaggttt
     1801 cagatgaaat caatgcttac tcagtggaaa ttgaggtaga tgttgatggt gtcaaggagc
     1861 cttggctgct catgtttaaa aatgaaacac ataatcaccc aacggaaatt gaaccctttg
     1921 ggggtgctgc aacctgtatt ggtggagcta ttcgtgatcc tctgtcaggc cgttcctatg
     1981 tttatcaagc catgcggctt tctggtgcag gggacattac aagcccgctg tcagagactc
     2041 gtaagggcaa attaccacag caggttattt cgaggcaagc agcacatggt tactcgtcat
     2101 atggcaatca aattgggcta gcgactactt atgttcgtga gtattttcac ccaggctttg
     2161 ttgccaaacg tatggagctt ggtgcggtag ttggtgctgc acccaaggaa aatgtggttc
     2221 gtgaaaagcc aaggacaggt gacgtggtgg ttttgcttgg tgggaaaaca ggacgtgatg
     2281 gtattggtgg tgcgacagga tcatctaagg ttcagacagt tgagtctgta gaaacagctg
     2341 gtgcagaggt ccaaaaagga aatgccattg aggagcgtaa aatccaacgt ctttttcgtc
     2401 gtggcgatgt gacacgcctc atcaagaagt caaatgattt tggtgctggt ggtgtttgtg
     2461 tagccattgg cgagcttgct gctggtctta acattaactt agataagatt cctttaaaat
     2521 atgctgggct aaatggaaca gaaattgcca tttcagaatc ccaagagcgt atggctgtcg
     2581 tgatttgtcc aaaggattta gaggccttta tgagcgcctg ccataaggaa aatatccatg
     2641 ctgctgttgt ggcagctgtg acagaaaaac cgaatcttgt tatgacctgg aatgggcaga
     2701 cgattgttga tattgaacgc tcatttttag agacaaatgg tgtgcgcgtg tctgttgctg
     2761 ctaaggttgt tgacagtggt gcgccaatac cagaagctcg tcaaactact gctgagacac
     2821 ttgaagcaga taccattgct gtcttatcag acctgaacca tgctagtcaa aagggtttgc
     2881 aaaccctgtt tgatagctca gtgggtcgct ctacagtaat acatccgctt ggtgggcgct
     2941 atcaaatgac acctgttgaa ggctctgttc agaaattacc agttcaacat ggagtgacaa
     3001 agacagtctc tgttatcgct caaggctatc acccttatat agccgaatgg tcaccttatc
     3061 atggtgctgc ttatgctgta attgaggcaa ctgctcgtct ggtcgcaacg ggtagccatt
     3121 ggcataaggc acgcttttca tatcaggaat atttccaaag aatggataag caggcagagc
     3181 gctttggtca accggtggca gccttgcttg gagcaattga agcacaggtg cagcttggct
     3241 tgccttctat tggaggtaag gattcaatgt ctggtagctt tgaggaattg acagtgccgc
     3301 cgaccttggt tgcctttggt gtgacgactg ctcatgtaga tcatatcctt tcaccagaat
     3361 ttaaagctgc tggcgagaat atttactata ttccaggaca ggctatttcg gaagtgattg
     3421 attttgagtt gataaaatct aattttatga cttttgaggc tattcagaaa aagcataata
     3481 ttagctcagc ttcggctgtt aaatatggtg gtgttgttga agcactggct cttgctgcct
     3541 ttggtaatcg gttaggggct tgtgtgacat taccagagct tgacaggagc ttaacagctc
     3601 agcttggtgg ctttatcttt acatcaaaag aggaaatcac aggtgttatc aagcttggtc
     3661 aaactaccag tgactttaca ttggttgtca atgatgtcaa gctatctgga gctcgtctct
     3721 taaaggcttt tgaagggagc ctggagcagg tttacccgac ggtatttcag caggcaggtg
     3781 aattgaagcc tgttcctgta gtgacaacag cacttgctgc tcagtttaag gaaaaaatag
     3841 ctcagccagt tgtctatatt ccagtttttc caggaactaa ctcagaatat gattcggcta
     3901 aggcctttga aagagagggt gcaagggtga acttggtgcc ttttgttacc ttgaatgagg
     3961 cagctattga cgcttcagtt gacacgatgg ttgaccatat tcatcaagct catattatct
     4021 tccttgcagg tggtttttca gcggcagatg agccagatgg ttcagctaaa tttattgtta
     4081 atatcctgct gaatgagaag gttcgaatgg cgattgatgc ctttattgaa aagggtggtc
     4141 tgattatcgg tatttgtaat ggctttcaag ctctggtcaa atcagggctg ctgccatatg
     4201 gacgttttga ggcggtacat gaggctagtc caactctgtt ttataatgat gccaatcagc
     4261 atgtggctaa aatggtagaa acgcgtattg ccaataccaa ttctccttgg ctggcaggtg
     4321 tcagggtggg ggatattcat gctgttgcag tgtcacatgg agagggcaag cttgtggtaa
     4381 cagaaagaga attagcagag ctttgtaaaa atggtcagat ttttagccag tatgttgacc
     4441 ttgatggtaa tccaagcatg gatagcaggt ataatccaaa tggctctgtc aacgctattg
     4501 aaggtcttac cagcaaaaat ggtcagatta tcggtaagat gggacattca gagcgctttg
     4561 aagagggact tttccaaaat attccgggta ataaggatca atggttattc cgaagtgcgg
     4621 tgcattattt tagaggagac catgtgggta ttgactgaac tgggatatag ccttgtaata
     4681 gctaagatag ctgctattat tgctcagcct agctgttagt tctagcttag ttaatgacac
     4741 aatcataatt aaaagggcat tagcccagag gtaaagatga catatgacgt aaaatctctt
     4801 aatgaggaat gtggtgtttt tgggatttgg ggacacccac atgccgctca agtgacttat
     4861 tttgggcttc atagcctaca gcaccgcggc caagagggag caggtattat ttcaaatgat
     4921 aatggggagc ttcatcagca tcgtgatgta ggtctcttgt cagaggtgtt taaggattca
     4981 tctgatctgg acaagctaaa gggacatgct gccattggtc atgtgcggta tgcgactgct
     5041 gggacggctt ccattaataa tattcagccc tttttatatc gttttacaga cgctcaattt
     5101 ggcttgtgcc acaatggtaa tttgaccaat gctatgtcat tgaaaaaagc gttagagagt
     5161 gagggagcta tttttaatgc ctcttctgat acagaaattc taatgcattt gattcgtcgt
     5221 agtcatcacc cagaattttt aggaaaggta aaagaggcac tcaacactgt taaagggggc
     5281 tttgcttacc tgctgatgac agagaaccag ctgatagcag cgcttgatcc aaacggcttt
     5341 aggccgttgt ctataggccg tatgaaaaat ggggcttggg tcgtctcaag tgagacctgt
     5401 gcctttgaag tggttggtgc tgagtgggtt cgcgatgtga tgccaggtga ggtcattatc
     5461 attgatgatc aggggatcac ttatgactgc tatacgacta ctacgcagct ggctatctgc
     5521 tctatggaat atatttactt tgcgcgtcct gattcaacca ttgctggagt caatgttcac
     5581 accgctcgca agcgaatggg aaagagactg gctcaggaat ttcagcatga ggctgatatt
     5641 gtggttggtg tgccaaattc ctcattatca gcagcgatgg gctttgcaga agcatcaggc
     5701 ctgccaaatg aaatgggatt ggtcaagaat caatataccc aacgaacctt tatccaacca
     5761 actcaggagc ttcgtgagca gggagttcga atgaaacttt cagctgtttc aggtgttgtc
     5821 aagggcaaaa gggttgtgat ggtagatgat tctattgtca gagggacaac ctcacgacgc
     5881 attgttaatt tgctgcgtga agcaggagct acagaggttc atgtagcaat tggtagccct
     5941 gagctcaaat acccttgctt ttatgggatt gatattcaga caagacggga gctgatttca
     6001 gctaatcata ctgctgctga ggtctgtgat attatcggtg ctgatagcct gacttatttg
     6061 tcacttgatg ggcttatcga ggctattgga cttgatacaa aagcaccaaa tggtgggctt
     6121 tgtgtggctt attttgacgg tcagtatcca acgccgcttt atgattatga ggaggcttat
     6181 ctcaagagct tagaagaaaa ggtaagcttt cacattgatc aggtgacgaa gtagcgcttt
     6241 atggctaaca tagaataaat gatctaggca gctaaaataa ggaggagaaa atgtctaaaa
     6301 atgcttatgc tcaatcaggt gtcgatgttg aagcaggcta tgagcttgtt gagcgaataa
     6361 aaaagcatgc cgagcgtagc aaacgattgg gtgttatggg tggtctagga ggctttggtg
     6421 gtctgtttga cctgtcaaag actggtgtta aggagcctgt tttggtttca gggacagatg
     6481 gcgtcggaac aaagctaatg cttgcaatcc agtacgataa gcatgacacg attgggcagg
     6541 attgtgtggc aatgtgtgtc aatgatatta ttgcagcagg tgccgaaccc ctgtattttc
     6601 ttgattacct tgcagcagga aaaaatgagc ctgccaaatt agagcaggtg attgcaggta
     6661 ttgctgaggg ctgtgttcaa gcaggtgctg ctcttatcgg tggagaaact gctgagatgc
     6721 ctggtatgta tggtcaagat gactatgatc ttgccggttt tgcggttggt attgctgaga
     6781 aatctcagct gattgatggt tcaagagtag ctgagggaga tcatctccta ggtttggcat
     6841 caagtggagt tcattcaaat ggttattcct tggttcgtcg tatttttgcc ggttatactg
     6901 gtgaggagct gcttccagag cttgatggaa aaaagcttaa ggaggtactt cttgagccaa
     6961 ctcgtattta tgtcaaggct gtgttaccac tcattaaaag cggcttagtg gcaggaatcg
     7021 ctcatattac gggtggcggc tttattgaaa acctacctcg tatgttttcc aaagaactag
     7081 ccgctgaaat tgaagaagcc agcttacctg tgctgcccat ttttaaagtc cttgagacat
     7141 atggtaagat caatcatgaa gaaatgtttg agatttttaa tatgggtatt ggcatggtgc
     7201 ttgctgtcaa gcctgagcac gttgagcagg tgaaggcctg tcttgatgag cctgtgtatg
     7261 acattggtcg cgttgtgacc agaacagttg ctagtgtggt gatgaagcca tgacaagaat
     7321 tgccgttttt gcttctggta atggctccaa ttttcaaacg attgcagaac agtttccggt
     7381 tgcctttgtt ttttctgatc attgcgatgc tcatgtttta agtagagcct gtgctttggg
     7441 tgttctgtcc tacagctttg aactaaagga ctttgagaat aagcaagcct atgagcagac
     7501 tcttgtggca ttgctgcagc ggcatcagat tgatctcatc gtccttgccg gctatatgaa
     7561 aattgtgagt acaaccttac ttgatgctta cgaaggaaaa atcatcaaca ttcacccagc
     7621 ttatttgcca gaatttccag gagcacatgg tattttagat gcttggcaag caggtgttag
     7681 tcagtcagga gtgactgttc attgggttga tagtggtatt gatacaggaa aaatcatcaa
     7741 acaggtacga gtaccacgtt tgagtgatga tactcttgaa agctttgaag ccagaattca
     7801 tgaagcagaa taccaattgt atccagaggt actggatagt cttggagtag agcggcttaa
     7861 ccgctgattg tgtaagatta ataactattt tccctattgt ggcatttcgt ttatcatagc
     7921 agctgcgcta atggtggcta acaaaggcta gaagacttgt ttgatgatgg cactgctatt
     7981 gaggaaaata gacttttcta aggagaactt aaaatgacta aacgcgcctt aattagcgta
     8041 tcagataaaa gagggattgt ggaccttgct agggagctta agcatcttgg ctgggatatt
     8101 atatcaacag gaggaacaag gcttgctctt gaagaggctg gtgtagttac tgttgctatt
     8161 gacgatgtga caggctttcc tgaaatgatg gacggacggg taaaaacgct gcaccctctc
     8221 attcatggtg gcttacttgc tcgtcgtgac attgagcacc acttacaggc agcaaagcaa
     8281 aacaggattg aattaataga ccttgttgtt gttaaccttt atcccttcaa agaaaccatt
     8341 tgccgtccag atgtcactta tgatgtcgct gttgatatgg ttgatattgg tggtccttca
     8401 ctgctgcgtt cagcggctaa aaatcatgct agtgttacgg tagtggttga tccgacagat
     8461 tatccgctcg ttttaggaga gttggctagc actggcagta caagttacca aacccgtcaa
     8521 agcttagcag ctaaagcttt tcgccatact gcagcctatg atgcagtgat tgcagattat
     8581 tttacaagac aagcaggtga gacaaagcct gaaaagctca cgcttaccta tgatttgaag
     8641 caaagcatgc gttacggtga aaatcctcaa caggctgcag atttttacca aagagcgctc
     8701 ccaacaacct attcaattgc ttcagccaag cagctaaatg gaaaagagct atcattcaac
     8761 aatattcgtg atgcagatgc tgcgattcgt attattcgtg attttaagga gcgtccaacc
     8821 gttgtagcac tcaagcatat gaatccatgt ggtattggtc aggcagatga tattgagaca
     8881 gcttgggatt ttgcttatgc agctgatccg gtgtctatct ttggtggtat tgttgtccta
     8941 aatcgtgagg tggatctagc gacagcggag aagcttcatg ctatttttct tgaattgatc
     9001 attgcaccag gctattccaa agaagcgcta gctgttctca cccataaaaa gaagcacttg
     9061 cgaattcttg aattgccatt tgctgctcag gaggctagtg aaatagaagc agaatataca
     9121 ggagttcttg gtggtctact agtgcaaaat caagatgttg tcacagagtc tccagcggat
     9181 tggatagtgg tgacaaagcg tcagccaaat gaacaggaaa tggctgctct agcatttgct
     9241 tggaaaacca tcaaatatgt caagtctaat gcgattgtca ttgctaatga tcatatgact
     9301 ttgggcgttg gtccagggca aacaaaccga atagcctcta ttcgtattgc tattgcgcaa
     9361 gcaacggggc agcttgaggg agcagttctt gctagcgatg ccttcttccc atttgcagac
     9421 agcattgaag aaattgctgc cgctggtatc aaggctatta tccagcctgg aggctctatt
     9481 cgtgattcag aatctattgc agctgccaat cagcatggta taaccatgat tttcacaggt
     9541 gtgaggcatt ttagacatta ataaagtaaa aagagactgg agccaaaaga gttgcacttt
     9601 agaaattctt ggttaatata ctttattacc tagttggatt cattaaaaag cgaacaagtc
     9661 tagttttcat aatctcagaa aactagactt gtttgcttgt tttatttggt ggtcatacta
     9721 ttgtttcagc ctctttttac tatgactaat acaagaattt atgaaggaac aaggctttat
     9781 tttttgttgt ggtaacagtg accagatccg ttatcaatca gtatttgagt attttgagct
     9841 ctagatgcat cacttagata ggatattgca aaggatacag ctgctgcatg tattaggaaa
     9901 gcattatcat aaaaggcttt ttcgttagcc taaaggtttt agaccttctt tgccttatct
     9961 attgttaacc atgttccacg tgaacccatt tgcacgtaaa tccccttgct aggctgatca
    10021 acctttagaa ccttataggt tcctgaaacg acaaaataat cacccacctg caaaatctga
    10081 tttccagcaa tacgtccttt atggtccgtt tcgtggagtg gagctgagtc tatccagttt
    10141 aaggaggttg gctctccacc ggctaattca ctgcttgcaa tcatgttctg agcgacctga
    10201 tcgacccgaa aaacaccagg aaaggctaca gtatctccaa ccttgatagg agtggtcgcc
    10261 acaggctttg gtttatctat agaggcttga ctatgttgct gaggctgaac cggcaatttg
    10321 tgaattggaa tgtagcgatg atttcctgaa tgaccgatat agctgagcca ttcatagcca
    10381 tcagcgacaa gggtttgatc atagtgcact aactgtccag tatgatagta agctaaatca
    10441 ggacttgcta atgtagcttc agcctttata ggactttggc ttgaaaaata ataggtacca
    10501 cttttagcta gacgagttga tcctgcttga gaagcatgta acatttgtgt gtggctggta
    10561 gagttgtgat ccagatcctt gaagtgaatg taaccactta cctgatgctt atgaatctgt
    10621 cgtttatgat acttttcagg tccctgtccg gcattatagt tgtattcctc aataataaca
    10681 gtgtcaccat tgacctctgc tacccaggcg acgtgtccat atagggcatg tgactggtta
    10741 aagcccttat cccaccaagc aacagcacca actctaggtg tatgatcaac atgatagcct
    10801 tggtgtttag ctatacgtcc ccagctttca acattaccat agcctctagg caggctgaat
    10861 ccatttgagg aatgcagtcg gaatgctaca aaagaagtgc attgacgtaa gtacatgttc
    10921 caaggatcag ctccgaagcc ctgtttccac ttacttggat agttatcccc taaaacagca
    10981 gcgtgtacga tacctgactg accttgtgaa atcgttgttg tggcagagga tattgcacca
    11041 ttaccaccta aaaggattgc tcctgaagct aacaattgat agactttttt cattaattac
    11101 ctcctgtaac ttactattcg caagaaagag gacaaaaatg tccttgattt aaaaaaatgt
    11161 aaggaaaaat attttagcct caaaatactg ttggtgctcc ctagcttcca agagccaata
    11221 ggcaagccca tctccagctt gcctgctccc tgtagctaaa agcaatttat agtaacacta
    11281 gcacctcatc tgaagaggca ggctgtggta attaatgcca ataatctgta aaaagagaca
    11341 gcaggtatgg ttatatgagc tatgatggtt atattctata aagcttattt tttagcttcg
    11401 ggctttcttt ggtgattagt tatttatata aacgaacaat tatgctaaaa tatgtttata
    11461 aaattcgtgt tatgaggtgt gtgatgaagc ttttagttat cggttcaggt ggtcgtgaac
    11521 atgcgattgc taagaaattg ttagagtcaa aaggcgttga acaggttttt gtggcacctg
    11581 gcaatgatgg catgaccctt gatggcatag aacgggtaga tattgatatt tccgaacatt
    11641 ctgctttgat tgcttttgca aagaccaatc atatagcctg gacctttgtg ggaccagatg
    11701 acgcattagc ggctggtatc gttgatgagt ttaaccagtc tggcttgaaa gcctttgggc
    11761 cctctcgttt agcagcggag ctggagtggt caaaggactt tgctaagcaa atcatggtca
    11821 aatacggtat tccaacagca gcctatggca cattttctga ttttgcaaaa gccaaggcct
    11881 acatcgagga aaagggcgcg ccaattgtgg ttaaagcaga tggtttggcg ctaggaaagg
    11941 gtgttgtcgt agcagagact gtagagcagg cagttgaggc ggcgcgtgac atgctcttgg
    12001 ataataaatt tggtgattca ggtgcgcgcg tggtgattga ggaattttta gctggtgaag
    12061 agttctctct ctttgccttt gtgaatggcg atcagtttta cctcatgccg acagcgcagg
    12121 accacaagcg ggctcttgat ggtgacaagg ggccaaatac aggtggtatg ggggcttatg
    12181 caccagtgcc tcatctttct caaagtgtgg tggatacagc agttgagacc attgtcaagc
    12241 ctgttctaaa agggatgatg acagaggggc gtccctatct tggaatcctt tactgtggct
    12301 tgattttgac agaagatgga ccaaaagtga ttgaattcaa tgctcgcttt ggtgatcctg
    12361 agactcaggt tatccttcct cgcctgacct ctgattttgc acagaacatt accgatatat
    12421 tagagggcaa cacagctaat atcacatggt cagacgaggg agtgacgctc ggcgttgtcc
    12481 ttgcttcaaa cggttatccg cttgcttaca agaaaggtgt gcttctgcca gcaaagacca
    12541 ctggcgacat cattacctac tacgcagggg ttaagcttgc ggaaaatggc aaagcactgc
    12601 tgtcaaatgg tggacgtgtc tatatgctgg tcaccacagc agttaccgtc ccagctgcgc
    12661 aagaaaaaat ctataccgaa cttgctcagc aaaataccga aggattattc taccgaaacg
    12721 atattggaag aaaagcagta aaataaatta gcgctagctc aagctaccga aggtcgctat
    12781 gatgacaatg acttattatc ggtgagcaaa agcgagccta acacgatact tttcgccgta
    12841 gcgcaaagag tgacaaggtc actcggggga acttgaaaga ccttgggctt tcaagttagt
    12901 catgagacac ctatggtggc tgttgacgcc cccccccact taagaaaagt atcaaaaacc
    12961 tttaaggaga aagtatgaaa ccaattatct ctatcatcat gggctccaaa tctgactgga
    13021 ccaccatgca aaaaaccgcc gaaatcctcg accagtttgg ccttgcctac gaaaaaaaag
    13081 tggtctctgc ccaccgcacg ccggatctca tgttcacata cgctgagaaa gcacgcgaac
    13141 gtggcattaa aatcatcatc gctggtgctg gcggagcagc ccatctccct ggaatggtcg
    13201 ctgcaaagac gacacttcct gttatcggcg tacctgtcaa atcgcgtgct cttagtggtc
    13261 ttgattcgct gtattcaatt gtgcagatgc caggtggtgt gcctgtggca actatggcca
    13321 ttggagaggc aggagcaacc aatgcagcac tgactgctct tcggatcctt tcaattgagg
    13381 atgaaacaat cgcagagcag ctcagccatt tccacaaaga gcaaggacgg atcgcagagg
    13441 agtcaaccca tgaactcaac taaaacaatt ggaattatcg gaggtggtca gctgggacag
    13501 atgatggcga tttctgccat ttatatgggg cataaggtca ttacactgga tccagcagcg
    13561 gattgcccag cctcgcgcgt gagtgaggtt atcgtggcgc cttatagtga tgtggaggcg
    13621 ctgcgtcaat tgaccgagcg ctgtgatatt ttgacctatg aatttgaaaa tgtggacgct
    13681 gacgcccttg atacagtggt aaaggaggag cagctgcctc aaggaacaga gttacttcgg
    13741 atctcgcaga atcgtatttt tgaaaaagat tttttagcca ataaagcaag cgcggcagtg
    13801 gcaccctaca aggttgtaac ctctagcctc gacttggaaa accttgactt ttcgaaaaaa
    13861 tacgtcctca agacagcgac aggtggctat gatggacacg gtcaagtcgt tattcgctcc
    13921 gaagcagacc ttgaagaggc taataagttg gctaacactg ccgagtgcgt cttggaagaa
    13981 tttgtcagct ttgaccgaga gatttccgtt attgtatctg gcaatggcac agatgtcact
    14041 gtctttcctg ttcaggaaaa tatccatcgg aacaatatcc tgtcaaaaac cattgtccca
    14101 gctcgcattt cagaagcagt tagcgctaaa tcgcaggcta tggcggtgaa aatagcagag
    14161 cagcttaacc tatctggcac cctctgtgta gaaatgtttg tggcaggcga cgagattttg
    14221 gtcaatgaaa tcgccccacg tccccacaac tcaggacatt actccatcga agcctgtgat
    14281 ttctcccagt ttgacaccca cattttaggt gtattaggcc agccattacc agctgtcaaa
    14341 ctccatgccc cagccattat gctcaacgtc ctcggccagc acatggaaca agcccaacgc
    14401 tacgccacag aaaaccctag cgcccacctc cacctctatg gtaaaataga agccaagcac
    14461 aaccgcaaaa tgggacacgt gacggtgttt aacagtcaat cagatgaggt tgaagaattt
    14521 taggaggaat taatcctatg ataaaaatca ttgttcacgc ttttattgaa aatggtgaaa
    14581 caggtgttgt tgaagttgtc tttgcttcgg aaaaccaaga atccatttct gaaaaaatga
    14641 cggagctaca aaagcaatat ccaaacgatt accttgctat ctatgattta ccactagata
    14701 cagacctatc gcaattggcc cactatccgt caatagcgat aggcaaaggg gagtttgagt
    14761 agttaaggaa gattagtatt tcggattgag tgttattggg acaatttatg gctatgcctt
    14821 tcaaaagatt ggtcatgatg ttgagcatgt tgtgagaatt gagaatcgta atcagatttc
    14881 agaagttggt aaatgactta atggataatt ctagatactg atctcgagca atcataagag
    14941 aaatgttgaa attgtagctt ctggaggtgt agaactcaaa aattatcgtg gtgagatatt
    15001 tccatataaa acttctaagc gtatttcgtc tagattgata acatatagat aggtttgtac
    15061 ataatgaact tactagatgc atcatgacaa agcagatctt ttatatacat gcaaagaggt
    15121 ttacaatatt ggtatagtca actattgatg ccctaacttt taatcacaat atagaaatta
    15181 ttgcgaatag actttaaaag cattactatt aactatgtag aaaggaaatg agcgctagaa
    15241 ttttcaaact gaacctgagc ggaaagctcg gaatttagat aaatttcctc ggacgtaaat
    15301 gtccgtcttt agctttctaa aattcagttg ctttctggct gttcttggta tcttaattat
    15361 gctaaaccgt tattcacgcc ctgagatggc gaagatttgg agtgaagaga acaagtaccg
    15421 tgcttggttg gaggtggaaa tcctcgctga tgaggcatgg gctgagttgg gtgagattcc
    15481 caaggaagat gtggcgaaga ttcgcgccaa tgcgagtttt gacatcaatc gtattttgga
    15541 gattgaagaa gagacccgtc acgatgtggt ggcctttact cgtgcggtgt ctgaaacgct
    15601 cggtgaggag cgcaagtggg tccactatgg cttgacatcg actgacgtgg tggatacggc
    15661 ctatggctat ctctacaagc aggctaatga cattatccgt cgtgaccttg aaaactttac
    15721 caacattgtg gctgagaagg ctaaggagca caaaatgact atcatgatgg ggcgtactca
    15781 tggtgtgcac gcggagccaa cgaccttcgg tctcaaattg gcgacctggt acagtgaaat
    15841 gaagcgtaat caagagcgtt ttgagcatgc ggctgctggt gttgaggccg gtaaaatctc
    15901 aggtgctgtt ggaaactttg ccaatatccc accatttgtt gaggagtatg tctgtggcaa
    15961 gctaggcatt cgcccgcagg aaatctcaac tcaggtcttg ccacgagacc ttcatgccga
    16021 gtacttcgca gtgcttgcta gtatcgcgac atcaattgaa cgcatggcaa ctgaaattcg
    16081 aggcctgcaa aaatctgagc aacgtgaggt agaagagttc tttgccaaag gacaaaaggg
    16141 aagctctgcc atgcctcata agcgtaaccc gatcggctct gaaaacatga cggggcttgc
    16201 gcgtgtcatt cgtgggcaca tggtgacagc ctatgagaac gtggcgcttt ggcatgagcg
    16261 tgatatttcg cactcgtcag cagagcggat tatcacacca gacacgacta tcctcatcaa
    16321 ctacatgctc aaccgttttg gcaatatcgt caaaaatttg acagtctttc cagaaaacat
    16381 gactcgtaac atgaactcta cctttggctt gatttacagc caacgtgtga tgcttaagct
    16441 gatcgaaaaa ggcatgacgc gtgaggaggc gtatgacttg gtacagccaa agacagccta
    16501 ttcatgggac aaccaagtgg acttcaagcc gatccttgag gcagacgaaa atatcactgc
    16561 aaaattaagg caagatgagc ttgatgagct cttcaatcca gcttattata ccaagcgtgt
    16621 cgatgctatt ttcgaccgat taggattata ggaagaaaac agcgcgtctt tttagactgt
    16681 agctaagccc agatttgttt aaaaagtctt gaaaatgaat tcctcggagc taattctcaa
    16741 aatgaagaat agtatttcaa gagaggctgt cactagctat atcgcttaag aaaatgctct
    16801 aaaatagaca ttttttcaat ctgagaaggc aataggcctt c
//
LOCUS       DARYVE010000048        16701 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYVE010000048 DARYVE010000000
VERSION     DARYVE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16701
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..902)
                     /locus_tag="TVW25_001456"
     CDS             complement(<1..902)
                     /locus_tag="TVW25_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1379078.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..2391)
                     /locus_tag="TVW25_001457"
     CDS             complement(895..2391)
                     /locus_tag="TVW25_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1379079.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILELLNANLS
                     WISKNTSLKIEYKVIKDNYITSQTLEYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANE
                     ALSMPDICYGSPNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVV
                     LKHIHLFVSRDKVFDKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTVFEAS
                     YDMVVSGEHKYVFLITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEALRND
                     AEEKAVPLFYSQHIKDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKEEKRR
                     LQCGIYLAKKFPTYKAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYRILNG
                     STQVNATEINSMPIPPLTCIEDMGKELIKLKDMSEENCDEILGRFIYV"
     gene            complement(2375..2590)
                     /locus_tag="TVW25_001458"
     CDS             complement(2375..2590)
                     /locus_tag="TVW25_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1379080.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            complement(2740..3399)
                     /locus_tag="TVW25_001459"
     CDS             complement(2740..3399)
                     /locus_tag="TVW25_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1379081.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            complement(3443..5353)
                     /locus_tag="TVW25_001460"
                     /pseudo
     CDS             complement(3443..5353)
                     /locus_tag="TVW25_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(5461..7226)
                     /locus_tag="TVW25_001461"
                     /pseudo
     CDS             complement(5461..7226)
                     /locus_tag="TVW25_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            complement(7736..14566)
                     /locus_tag="TVW25_001462"
                     /pseudo
     CDS             complement(7736..14566)
                     /locus_tag="TVW25_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(14738..16165)
                     /locus_tag="TVW25_001463"
     CDS             complement(14738..16165)
                     /locus_tag="TVW25_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1379082.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            complement(16184..16363)
                     /locus_tag="TVW25_001464"
     CDS             complement(16184..16363)
                     /locus_tag="TVW25_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1379083.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            complement(16447..>16701)
                     /locus_tag="TVW25_001465"
     CDS             complement(16447..>16701)
                     /locus_tag="TVW25_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1379084.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
BASE COUNT         4514 a         3677 c         2353 g         6157 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgtagttat
     1621 agtaatgttt tttaacttat ttaattcttt cttggcttta ataatcatag tttcttgcaa
     1681 aacagactct ttatcaaaga ctttgtctct gcttacaaat aaatgaatgt gcttcaaaac
     1741 cacttcattt aaaaacttct cacgaaactt tttaaagtac gctccagaag tccatgatct
     1801 tggaacgata aacaccaatt cgccattatc aaccaaattg aaacttgcca tctccataaa
     1861 aagaaaatat aaattcggtg atccataaca aatatcaggc atggataaag cttcattagc
     1921 catttttcca acctttaaat aaggtggatt tcctataatt acatcgtatt tttcaggttt
     1981 agtactcacc cccaacatat tgttatattc aagtgtttga cttgttatat agttatcttt
     2041 aatcactttg tattcaattt ttagtgatgt attcttactt atccacgata aatttgcatt
     2101 taacagctct aaaatatcat cattggtttc ataacaagta atttttatgg cttcaatctt
     2161 atcagtatca ataattcttt gaataagagc tgccgtaagt attcctgaac ccgctcccgg
     2221 atcgagtata gaaatttctt ttgaaaatga tgataaatca aataatgatg ccatgaaaag
     2281 agctgtttct ttacttgtga aaaattgccc atttttcttg cgaatttctt ttggcatctg
     2341 tttaatatat ttatttgtag attcaattac ataatcaatt attttcatca tccaccaact
     2401 ccataatttc atttacacca cagttcaaac tatcacatat tctgacaatc acatcagtag
     2461 taatattctc actgttcttc attttataaa aagtactccg gctaacttct gctttttcca
     2521 ttagctcaga atttttcata tctaaatcta tcattttttt aaatagcttt ttataactta
     2581 ttttcgacac gattgtcctc ccatgcatat gattttgttt ttatcattat atcatattta
     2641 ttcacttttt tcactacaaa cttcctttta cacaaacaca cgacatttag atagacaaaa
     2701 aagagtcggt gcagtcctaa gaccacaccg accatatatt tatctctcag cttctttgct
     2761 tgcgtctctc ttttcttttg gtttttcctt atcttcagac tgatatttct tgatagctcc
     2821 aagaacagat tctttctttt cttcttgtcc tttcatttgt tcctttgcct ttaagagctt
     2881 tgaagaaagt atccttacat tgctatgctc cttgccatta tcatcaatgg aagttctgat
     2941 ttgtccaaag agctttacaa aatctccctg cttaaagtct tttggaatat cactcttttc
     3001 tccataagcg gagcaattat gataaacctt atttccctca tcatctttag atacaacaga
     3061 gaaatttgcc accttaaagg cttctccatt cttgttttct ctttcagcta catcaacctt
     3121 tcctacaata tttccaacga tattgataag attatctttc tcttcctgaa catagggcag
     3181 gtcttttatt tgcccctgtt ctcgtaaatc ttcaatcatg tagtcaaatt cctcatgcag
     3241 taaattcaga ctgtcattgt ccatataagc gtcatagagc ttgtccaaag cactttcatc
     3301 attgatacct ttctccacgc ttataatcgc ttttacaaag tccttgtggt tatcatttgc
     3361 catatcttct atttgatttc tcattgtttt gtaatccatg ttttttatct cctttcatag
     3421 taaaagggag gttaccctcc ccttatctta aaaattcctg ttcttttgta gtttgttttt
     3481 cttctgtttt actttcttcc tgataggctc ttatctgtcc taaaatagat ggcttatcct
     3541 ctgatttttg tgaactttct tctttgctat gaaaattatc ctccacatca tatgttgatt
     3601 caaaatagtc gctgtcctta aagtcattat cgtaacggtc agtaattccg tcattatcaa
     3661 ggtctttaga aagcggatca tagaagttac cttcgtcatc aatatcaagt cccgttgctg
     3721 ctttcaaatc ttctgaatcc acataaacca gatcttcaaa agaggatagc tcaatctcat
     3781 ttttcatatt tcttagagtt tcattctctc ctttgttctc atagtcaaag ctctcagttt
     3841 ttatagatat atcatcaata tactgtgtcc atatcttatc ctctaaatta agctcatatt
     3901 gaatgctgtg tctttcatcc ggcgtgttgg tataggcaat tcctatatgc tttaagtcag
     3961 gatatagagc atcaaactca tcgtagctat gattttcttc atattctctg ttacagaaat
     4021 caataattgc ccttttaaca tcttctacaa ggggattatc atttctcttt tcttccacat
     4081 cacccatatc aagtagctta tttagttcag ccaagcgaag caccttactc tttaattcat
     4141 cagctttttc aaacggcttt tttaattcct ctttggcatt ttcaagctgc tctttggtgc
     4201 ttatgagctt ttcttcaagc ctctttaatt tctcaggcat tttctcaaga gcgttatcaa
     4261 gtcttgtaat attaccgtca gcacttgtgc caagctctcc tgaatgcttt gcaacaccgt
     4321 ttaagctgaa attatgagaa ttagtaaaga agttataact tgcttccaag tccatatttc
     4381 tgtacttacc gattacctta ctttcattga ttttaacctt tgaaatagct tcaagcaatc
     4441 tttctcctgc taatttctta tcggtaatct ttgctcctgc gatagtaata gaagtaaact
     4501 tttcctctcc gtccgcttta ggctctacat cagatatatc tttcttgaca gcttctatga
     4561 gcttttcagt tcttgcgatt tcttcaggat agtttttcgc cactttatcc tctaatctgt
     4621 aacggttgga cttatagttt gcttcaagca ttttaagttt cgtaacctca ttatccaaat
     4681 ccatcttttc tttaatcttc ggatcacctg tggcaagggc tttaatttct gcatagttaa
     4741 gtgaactttc atccacatct tctgccactc tgacaggtgt tttacttgtc ataatctgag
     4801 aaatgaactt ctgcttattc tctattgtct gccacaaata cgcatcaaag gtgttctccg
     4861 taacataacg atagatattt acttccttgt tttcattgcc ctgtcttaca attctgcccg
     4921 cacgctgctc taaatcggca ggacgccaag gaacatccaa atcatgaagg gcaatcagtt
     4981 tgttttgtac attcgtgccg gctcccattt tctgagtaga accaagtaat atcctcacat
     5041 ctcctttacg cacctttgca aagagttcgt ccttttgttt atcggaattc gcttcgtgga
     5101 taaaggcgat ttcttctttt ggtattccca ttgctacaag tttttctcta atatcatcat
     5161 agatgttaaa ttctccatcg ccttttggtg tagacatatc agaaaatagt agctgtgttg
     5221 acttatcttc ttttgtctta tcccatatac taaagacatt tttcacacag acattgacct
     5281 tactgtcagg attgtcaggt agcagaggat taattaaacg ctgatctaag gcaagttttt
     5341 taccatcatt agtgtagggt aggatactag cgaggtagtc attgcgaccc cttttccatt
     5401 atccccccac cgaaccggac atgatacttt cgcatcatcc ggctctccag taatttcatt
     5461 tcataaacgt gtatttattg aaccattatg tattgcatgg tgacaatccc gacaagtcac
     5521 tagcattttt cgacgtcttg ctgacatgat ttctttccac tttggaacta atttcccatt
     5581 gtgtttgttc aagtctgcta attttctgat atgatgtacc tctatgttct cctcacttcc
     5641 acatagctca cacttatttg cgagtaatcg cttgataagc tctgttcgac caccataaac
     5701 ttgatacgga gcatcttcta ttacagcttt ctttttatgc caccccacgt tgcaactaga
     5761 ggaggtttat cttctcgaga cacaactacc tgtaaacacg gcaccgttcg gccattcgtg
     5821 ctagttgtgg tagtcttata tttagctaac attttattaa tggatgactc atgtttaaat
     5881 gctaatgttt taaggagtga tgtttccata taccaataga cttttgagaa ccatgacaaa
     5941 ttttgtgcca atatataata ttgaactagc cctctatatt cttgttggta agtttgaacg
     6001 atactaaagt catcatcatg caataagtta ttacgatgaa tagctttacc atttttcatg
     6061 tattggcggc atttgctttc aataactgat gcaggtacaa ataatgcgat aacaccattg
     6121 gcactctgtc tccctttgtt atcaatataa tcattgacac gttgtgcttt tatctcatat
     6181 cccagaaatt tagctgattc tccagtcgca tgggtaatca aagtcttttc ttgagaaagt
     6241 tccaaagata acttagtatt taaaaagtct ccaatttgct tctttatagc ctttgcctca
     6301 gcttttgaac ctgtaaagcc tagaataaag tcatccgcat accgaacata tcttaatctc
     6361 cgatagctgg tatcataagt atcaactgaa gggagatttc ttctctcaac aattaactga
     6421 tgagcttttt tataatctcc tttatcctga tagcatttaa ttcttctact caaacgatta
     6481 taggctgagt ttgctttctg ctttttacct cttgtatatt gaggtatcag ctcttcaccg
     6541 acccacttat caaattgatg taaatagata ttagctaata aaggactaat aactccacct
     6601 tgcggtgttc cactaatagt cttgtgaaac ttccaatcat caagatatcc tgcctcaagc
     6661 atatttttga taagcctaat aaaccgacca tcctgaattt gtctagacaa catagtgatt
     6721 aatacatcgt ggtcaatcgt gtcaaaataa ctagagatat ctccttctat gaaccaacgt
     6781 gtccctttcc aagtctgaat ttcttgtaaa gctgtatgac accctctttt tggtctaaaa
     6841 ccatgagaat gttcactaaa ttgtggctca taataggctt ctaatatcat gcgaatcact
     6901 tcctgaagaa gtttatcact ccatactggt attcccaaag gacggtgttt tccattcttt
     6961 ttaggaatgt actctctcct agctggtctc cagtaatagg tttcttgtct taattgttca
     7021 ataatcatat ctattttttg aatagacatt ccatcaatcg tttcctctgt aacacccttt
     7081 gtcattgctc cattattcgg gtataacttt gcataggcta tcagatagag ttcacgatta
     7141 aatagtaact tataaaccct ttcgagtggt ttatcttgtt ttccacgttc atgaatgacc
     7201 gttaaaatag ttttggctgt acgcatccca cgcacctaat cctttctaac taatcgaaat
     7261 tacctgtcac ccttcgccat gtacaaggat ttcccttgct cggactacta cggtgactcc
     7321 gttaccataa gggtcccccc tcttaggcaa tcctgctatt cgttaaaaat gtacgttcta
     7381 gtaaccctta ggttcctcac tcattccttt attcatactt atcgtatgct cttttactgt
     7441 agaaagttat tcgtccaaaa tcacaacaac gaatatacag taacatcggt ctcagttact
     7501 ttccgatggg cgatgctttg cacctagtca gaattgaggt tcaagcagtt tagccttaac
     7561 cataggttac ggaacttgcg gcacatcaaa gcgttgtaac tcactcctta tccgctttac
     7621 taacatgcta ttgtcccctt tgggtttccc cgctaggtta gttagttgtt cctattattt
     7681 actttcaata atatccctct gtgagggaga tacattttta cgcttaacag cgcacaattt
     7741 ttagcatatt atctttgtca ggctctacca ccctatttct cacatcatct gctctttcag
     7801 aaaggctctt tagaatttcc ttttgctcct cacttggcaa ggtcttaatt acttcataat
     7861 gtgcctcagg tgttggaaga tttaacatat ccgctgtttg aatgtcagcg acttccttaa
     7921 acatagacat tagttcaggc aagttataga acttggaaaa tcttgtcttt actctgtatc
     7981 ctgttccctc cggagaaagc tcaaaagcag actgcgtttc cccaaaagta gaagcccagc
     8041 tatcaaaatg ctccagatta tttttcttta agctctcata ctgaagataa cgctgcatag
     8101 tgtaaagctc agtcatggag tttgatacag gcgttcccgt tgcaaagaca atgccttttc
     8161 cgtttgtcat ttcatccata tagcgacact tcataaacat atcggaggac ttaaaggctt
     8221 cactttgacc gattcctgca acattacgca tttttgtata aagatagaga tttttgtagt
     8281 tgtgtgcttc atcaacaaag agcttatcaa ctcctaattc ctcaaaggta atgacatcat
     8341 ctttcttaaa atcgtcattt aatttctcaa gccttgtttc cagttttttc tttgtctttt
     8401 caagctgttt tactgtaaag ttctgatttc tgtcatgctt gtattcttct acatagttta
     8461 cgatttcatc aatctgatct tggatatgct tctcctgata ttccttagac ataggaattt
     8521 tttcaaactg cgtatgcccg ataacaacgg catcgtattc tcctgtggca attcgaccga
     8581 taaaacgctt acggttcttc ggctcaaaat ctttcttatc tgccaccatg atatttgccg
     8641 acggatatag ctgcataaac tcacgaccga tttgtcctgt taagtgattg ggtacaacaa
     8701 acaaggactt actacacatt ccaagtcttt tactttccat tgcggaagcc accatttcaa
     8761 aggtctttcc actgcccacc acatgagcaa gcagggtgtt gcctccataa agacttcttg
     8821 ctatggcatt tctctgatga ggtcttaaat ctattttagt attcattccc tcaaaggaaa
     8881 gattacttcc gtcatattct ctgtttcgga tagagttaaa acgctcatta tacagtttta
     8941 caagacggtt tcttctctcc tgatcattaa atatccagtt cttaaattct tcttttagta
     9001 gttcctgctt ttgccctgca agcatggttt cttttttatt tagtacagaa gttttagagc
     9061 cgtccggatt tacaatctgg tcaaatacct ttgtttcttt caggtttaag gcatcttcaa
     9121 tcagcttata ggcatttacc cttgatgtac cgtaagtcat ttcagcgagg tcatttcctc
     9181 tatccctact tttaccttct atattccact cacttgtcag gtttgaaaac ttaaccttaa
     9241 tatcccatct tgcatatccc ggagttttca gcgtttcaaa aataaatttt tcaatatctt
     9301 taatcggtat ccaagtcgca ccaagacgaa cacttatctc acttgcttca agctcctttg
     9361 gtagaacttt tgtaagctca gccttttggt attccaaacg attcatctca tagctaatca
     9421 gctctttttc tttaccatct tctgcatagc caagatgagg taactctctt tccgtctgtc
     9481 tgagctttga tagatagcta tctactatgg caatcttgtc cctgatattc ccacttaaat
     9541 attcatcctt tgttacatag ccgtatttgt aggaattact gccattggca caggcaaaag
     9601 gcaaatctcc atcttcgggg ttaaaggata gaggtctata aaagttttgt tcttccctaa
     9661 tatttaagta gatttcccct cgaagctcct caatcaaagt cggtctgtct tttcctgtaa
     9721 gaccttccat atagtcaaag tccacatatc ctttttcaga taccgataag acaagggctt
     9781 ctaaagaagt atccacatga tctatgactt tagcctttgt aatagttctt ttggagaaaa
     9841 tatctccctt tgccttaaag ttttcttcat caaggatttc aatggaggaa acaagcggga
     9901 agttgctatc ctcttttaaa gctcttgtat tgcttaaatt atttacaaag ccatgcttat
     9961 tagaaaaacg gtcatagact tcatttagtt tttcctgtga agccttgatt tcttcctcac
    10021 taaaaccttc tttctgcttg taaatcacat tttttaaggc agcattcagc tcaagataat
    10081 ccttgatttt ttctttgttt ttatcggtta cttccttttt gataaacagt gagttttctc
    10141 tgtaatagac ttcatcatca ataatggtat aggaaaagtt cttaacatca tccgttgcag
    10201 ggattgaagt gatttcatca tctaaaagct ctatttcttc atacttggca tcttttgaaa
    10261 ttctttctcc tgcaatctcg atacgatcct ttaatgaagc catatttagc tctgtgccta
    10321 aataagatat cggttcacaa gttagagttt ttccaaatct tccgcttact tcacgcattg
    10381 agccaagtac ctgttcagga tgatcaacaa agtatttgtt atatacaaga ccgttttcat
    10441 cttccgcaag gtgtatccaa tcttcatcac gctctaatac gctatctctt ttctttaaga
    10501 agataatatc tgaggttact tctgtgccgg cagtaccctt aaaggtgtca ttaggaagtc
    10561 tgatagctcc taaaaactct gctcttgctg caagatagcg tcttacactt tcatcctttt
    10621 tatccattgt tccacttgat gtaataaagg cgataacccc gccgtttcta accttatcaa
    10681 tggacttggc aaagaaatag tcatgaataa ggaagttatt acgattgtat tccctgtcat
    10741 ttactttgta ttctccaaag ggaacattgc cgattgcaac atcaaaaaag ttattggaaa
    10801 aagaagtttc ttcaagtcct ttaatctgta tatcactttc agggtataaa agttttccaa
    10861 tcctaccgct tatactgtca agctctacac cataaaactt tgacttgttc atttcatcag
    10921 gaagatttcc tataaagttt ccgatgccca ttgatggctc aaggatattt ccgctcttaa
    10981 atcccatatc ggaaagtgtc ttatatacgc cgtcaataac agttttcggt gtgtaaaagc
    11041 tcgttagggt agattctctt gcagcttcat attctgcctg agataagttt tcctttagaa
    11101 agctcctcgc ttctttccac tgtccgcctt tttcttcatc gaatacatca gcaagtccac
    11161 cccagcctac ataccttgct aaaacttcct gagctgtact gtcaaactct ctttgtccac
    11221 tttcgatgcg actcagcata gagatggctt caaggttatt atttagcctt tcacttggag
    11281 ataacttgtc aggtaatgtt tcttccgtaa tcttgaagtt atgagcttct gctttcttta
    11341 tttcactttc tttagcaata gtttcaggct ttttatatgt cagattttca aataccctct
    11401 caagatcgct ttcaagacga taaggaatta catctgagcc tgttatcata ccgccaagat
    11461 attcggtatt atccttaacc gttaccgtct ttagattatt tcccatatcg tcaaagcgtg
    11521 tgatggtata gtctttatcc ttgtatttaa tttcatctcc aacgataaac gcaggtcttt
    11581 cagggcttac ttgtcttaat aaatcttcat tatctgtaaa ggctacaata gggatttgat
    11641 ggtttccact tcttcccgga tcaagccata agtcatatct ttctgtgatt ttattttcag
    11701 caatttccct tacagtatat tcttcatgat taaaatagac ggtatcgccc tctttaactg
    11761 caaattcatc tgaaatactt ttcttttctt cgttaagctc tacttcttcc ttctccttca
    11821 gataatcaaa tagtgtttcc tgaacaggtg ttgcagctac tctttcttcc acttcttcag
    11881 atatttcaag ttcttcttta tcttcaaagc taagttctcc gttaaagact gattgaagtt
    11941 cctgttcatc catctgcttt gcaagttctg tatctttaag ctctctaaaa gtctttggaa
    12001 aatcctctaa aataagcctt tgagcattta attctttcaa ttcttcaaga ttgaaatatc
    12061 cccattcagg ttcaaatcct aacacaagtc caaaggcatc accgctttcc ctatcatatt
    12121 ccgtcatata ccaagtccag ttagaacgga aaggaataat atatgctgca tgaacctctt
    12181 tatccgctaa agctacatct tcctgtgcgt aaagctcagg cactctttca agcatttcat
    12241 cagtcattaa gttttcagga ttatctttag aataatattg tagctctttt gattcttcta
    12301 cctctgactt actttctatt ttcttttctt catacagatt tttagaaagc agctcctcta
    12361 tacgctttgc cacacttgac caagtaagaa aaacatcatt acaattattc ttctgtaatt
    12421 taagcccctt tgcatcatgc cattcatcac ttcccattgc ccccgatact gcatgacttc
    12481 taccacctat gccatattcg tcttttagga aattagcttt ttcctgcaag gtatgatttt
    12541 ctttgaaaaa ctttgtaatt cgctcttttc ctctatcgac gccacttcct cttgaaagac
    12601 tttcaaggac ttcatcttct gtaatgaagg actttacctt cggaagctct gttagattgg
    12661 tactatattc ctttcgtgac agctcaagtt cctgtaacct ctgacaaagg ctatctacct
    12721 tgtgatagtg aaaccttaat acatttctgt tttctttgta tccttctaaa aacctgctgt
    12781 attctttgat cgtttccttt aggtagtcgg gattttttaa tgcttcagac aatctttttg
    12841 tttcttccgg aaagcctctt ccacttgttt tcaatagttc aaaatatcct tgtccttctt
    12901 cgcttaaatc atgcattaga taccataagg actctgaaat cttatctctt tcataatcag
    12961 gagcctcaga aatctctaca tttgtagcaa actcaccatt atcaagaagc tcatttatcc
    13021 tctttgcagc atcgctccag cttaaaattt gcgtagtatc ttctcttgca gatgtcccgt
    13081 aggctaaatg aatgccttta tccgaatacc aggaagatac ttctctttca tcaatgtaaa
    13141 atccattacc gcctctaaat atatctttta ggtattctcc taattcttca ttactttttc
    13201 ctttagaaaa ctcagcgata acaggaagtc tacttccatc gtgatttcct ccgttaataa
    13261 ggacagtatc tatatccctc tgagttaatg gaatggtaag tctcatctgt ccatatgaat
    13321 tttcgggtaa agaaaaagaa gccttttcag cttctcttat ctctacctca gtattatctt
    13381 ttaaattttt aatacttcct tgattgtcat ttccttcaga gctgaaatca tcgccccata
    13441 ctgcggatcg ttctcgtcct ctatcttcca agctaccatc aatttcggct tctctgtcct
    13501 cataaagtct atcgcctgtt tctgaatatc catcaggtgt cctgttagct tcctctcctt
    13561 gtatagatcc actaacatct cgaagtggct ctgctcctcg ctctctgaaa ggtaatccag
    13621 cctcattact gcgtaggtcg gattcggata ctcccttatg aagtccgtct gttcctccaa
    13681 gctgtttagt gtattctccc tgattttctc tattatctcg tccgtactct ccatttcgga
    13741 gaactcgctc attttcattt ctttcctgat catctcgtcg aagtacatca ttatctcctt
    13801 tctcaatttt ttctttaatc ctattatatc ctgcttcttt tcctcttaaa acttcttttt
    13861 gaagctcaag ctctttgctt ttttgaatgg tttcatcaat aatctttcca ctaatatccg
    13921 atacgatttc accaagactc ataagggaaa tgctatcaag cattgcaaag ttttccttta
    13981 gaagctcatt atccatagga tagtctacat taaatcttga agctactgca taactcactg
    14041 agtccctcac aaacttggta aaagatattc tatcctcatc agctattcta agctcattca
    14101 taaggctgtc tatcttttca tcaccgtaga gtctacttaa agaaaagata ttttctaagg
    14161 tgctttcact ttcctcatag ccctcgtttt ttatcatttc ctttaagaca tccctatgag
    14221 cttctttatc aaatctccaa agattgacct cattgacatc cctatttctt gaaaccgtct
    14281 gacttatatc aaagatatat gccacttttt tgtatgtgcc gtagtcctct aaaatgggga
    14341 tacctttttg tcctctcata acagtacggt taaagcgttc cctccaatag tcgaacttgg
    14401 cacaggctgt cgcttcagaa tttctatcat aaatacttaa ctgacttcta aagtcatatc
    14461 tttgattgtt tccgacaacc tttaggagct tcaggtattc tgcttcactt tgcaaaatat
    14521 tttgttttac aagctccaaa atgttatgaa aatcatttat tcgcattttt acctccttct
    14581 ttttccaaac aaaaaaggcg gttagatttt actctaatca ccttttgatt ctgtgtattg
    14641 caacttgctg caacttaaat ttcctactac aaatcctcat tttatggtat tcatagcacc
    14701 ctcttattta taaaaatctt tgttttgcaa cttaatttta ttcattcagt tcccagtgtc
    14761 cgctattacc acttcctaca tacttcagat tatctatttc ctttatagct ctttcgatag
    14821 tctttacgct aactccagct tcatctgcaa tagcctttct tgtaatccta tcattgcttc
    14881 tcactttttc tttaataaac tctgcgagag ctatcttatc gtgagcgaca tcgtgagcga
    14941 caccctgagc gacatcgtga gcgacattgt cgcctccaac cttttgtgtc gctatcttct
    15001 ttagaggaat aatcgttctg aatatatctc cctcctcaaa tagcgggttt tgtcctgaat
    15061 aaagctgtgt gtatttgtag gtatttcgca ttcctgaacc aagttcatcc gcaagaccta
    15121 tttctctaaa aactttagat atagcaggat ttttaggaaa tggctcaaac ttctgtaaat
    15181 ctaaagctcc catcccatga gccaagttgc tgttttcaac tgtaatcctc tcatcgtcaa
    15241 taatcatctt tgcaggaaaa ccacttgaat aatctctatg agccagcgta ttggaaacta
    15301 tttctctgag tatcctgtct cttgcattga cattgacaat tccgtccaag acaaataaat
    15361 cattcaagtg cttttgtcca aattctatca gtctgtcata gctgtcaatc agatttgtta
    15421 tgacaacatc tctatcatca tatctatcct tattttcaac cctgaatata gcatcagttt
    15481 tgtgttgcgg aagaacggac ataatagagt tatcttttcc aaataacaaa atagcagcta
    15541 atgtgattcc ttcacgcttt gtttccggat ctgtcagtat caaattggca cttctaagaa
    15601 gctcctcatt actcatattt tcccaaacat gatttttatt tcggaaaaca gccattttct
    15661 tagctttatc aatgacagaa gcatcaagaa aatcaatatc aagattcgga tataccttat
    15721 taacaaaata gcttccttgt tttcttgcat atagcttata tacaagctct gaatgatctg
    15781 tgatattgat gtccccttca taagacctat cccaaattct tccgttatgt ctgcatacct
    15841 gataaccttc aggaactctt atataaataa cttgtttccc ctcaatttca aaagtttccg
    15901 gcagcaaata aagtggtgga tacatctttt gcggattgtt gattgccgta gtaaattcct
    15961 taatcacttt atctacttta tcttcactaa caccaacgat ctctctttta tcatttgcac
    16021 caagtaaaat atgtccgcca tttctattgt tgaaagagca tactgtatca aagacatctt
    16081 tggttaaagc gttcttggat tctttaaatt cgacatctat tttttctccg gcttgaatta
    16141 acttcttaat ttcatctatc gtcatctgtt tatttcacca cctttatttc ttaatgtttt
    16201 cttcgataaa aacattggaa ttttgaattt caactctatc tttattaact acaaaagtaa
    16261 catagtctcc attttctaaa ttcaaaagtt ccctaatcct ctttggaata gtaacctgtc
    16321 cttttgacat aactttagca gtatctataa atgtatcttt catgactaat ccctttcgcc
    16381 ctacttttcc tacaaaagat tatagcactt ttaagatatt ttttctactc tgaaattagt
    16441 gtcatcttac ttactataag ttgaaaccgc ttcttttatc tcattttcaa tcgcttctaa
    16501 aaattcttcc tttgaagatt tcccttgagc aatatcggat aattccattt cccattttgc
    16561 ggtagtttct gccgacttaa agttatcagc tacaatcgct acaaggctta ttcctttatg
    16621 tgtggctata aggtttttct tatctctttc tacaaatccc ttaaagatta agttttcaat
    16681 aatccctgcc cttgtgaact g
//
LOCUS       DARYVE010000049        15737 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYVE010000049 DARYVE010000000
VERSION     DARYVE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15737
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(419..2830)
                     /locus_tag="TVW25_001466"
     CDS             complement(419..2830)
                     /locus_tag="TVW25_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1379085.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVEEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2845..3768)
                     /locus_tag="TVW25_001467"
     CDS             complement(2845..3768)
                     /locus_tag="TVW25_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1379086.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4095..5642)
                     /locus_tag="TVW25_001468"
     CDS             complement(4095..5642)
                     /locus_tag="TVW25_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1379087.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6267..7148)
                     /locus_tag="TVW25_001469"
     CDS             complement(6267..7148)
                     /locus_tag="TVW25_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1379088.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7313..8314)
                     /locus_tag="TVW25_001470"
     CDS             complement(7313..8314)
                     /locus_tag="TVW25_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1379089.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8455..9627
                     /locus_tag="TVW25_001471"
     CDS             8455..9627
                     /locus_tag="TVW25_001471"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1379090.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9631..11115
                     /gene="galT"
                     /locus_tag="TVW25_001472"
     CDS             9631..11115
                     /gene="galT"
                     /locus_tag="TVW25_001472"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1379091.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11125..12135
                     /gene="galE"
                     /locus_tag="TVW25_001473"
     CDS             11125..12135
                     /gene="galE"
                     /locus_tag="TVW25_001473"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1379092.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12212..13255
                     /locus_tag="TVW25_001474"
     CDS             12212..13255
                     /locus_tag="TVW25_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1379093.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13556..13699
                     /locus_tag="TVW25_001475"
     CDS             13556..13699
                     /locus_tag="TVW25_001475"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1379094.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14313..14474
                     /locus_tag="TVW25_001476"
     CDS             14313..14474
                     /locus_tag="TVW25_001476"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1379095.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
     gene            complement(15066..15404)
                     /locus_tag="TVW25_001477"
     CDS             complement(15066..15404)
                     /locus_tag="TVW25_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1379096.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(15394..15681)
                     /locus_tag="TVW25_001478"
     CDS             complement(15394..15681)
                     /locus_tag="TVW25_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1379097.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
BASE COUNT         4568 a         3520 c         3097 g         4552 t
ORIGIN      
        1 aattgtacgg ctgctaacct ttttcctaac ccttttagac accaaaaaac tccccttatc
       61 gtttttagtg attgtttttc actgtccact ttaaagggga ggtctagcta ttaaaggcta
      121 ggcggttttg actggaggac tattaggtgt gaggttaatt ggtaaaaact ctttctgtgc
      181 tgccctcctt aggtcatata gactttcttg gaaccaaaac ccacatatag cctacagaga
      241 tccaatgctt taaaagctat gaggtgctaa gctgctgatc aagtcagctt ctctgactgt
      301 tgctgcaagc aaaagcctac taagcgatct taggctgtga ggcgtaagaa caggtcatca
      361 taccaatagc tttttgggga taagctgtga tttgtatgcc ttagctattt tatagtgttt
      421 atttgatttg ttgcaatgtt gtcacatcat aaagcattag gtgtcctttt tggtcataga
      481 atttgacacc ctctggcacg aaaataagat actccggttt aatgcctgct atttcagcta
      541 actgattgat ctgacgttca agagttgccc gatctaaacc ataattagga atatcgtcaa
      601 ataaagactt ggtctgctct atgccatctg cggcagtatc ttgcgctgac ggttcctggt
      661 ctttggttgg cttaatagtg ctttcagctg cgtctgaggt cttattgcct aataattctt
      721 gaaccttttg ccattcatca tgagataact catctttagt aatggttctt aaagagcgtc
      781 caccaactct aggaatgcta aaggaatcat tacgccaaac aaaggttcct tcagcaagaa
      841 cgtccttagg atcaaaaata tagccatctg gagctgcgta ccgacctgcc ttgatagctg
      901 cttggacctc ttcggcagag tgaataattt gccagttttc cattgaagta cgttgatcag
      961 ctggtgtgac attagcaatg actcctccag cttcatcatg atttgggtta gaccaaacat
     1021 caggacgagt attagggtgc tgcatgacat atttgatggt cgcaatctga tccttagtta
     1081 gccatgaata aggtacaaca tggatatgat cgatgtgagg aatgacaaaa gatgtccatg
     1141 tatcataggt tgcattacca gcatgcatcg gtaggctgga tacctctaca gctagctttg
     1201 gctgaacgcc tgtatcaaca atgtcataaa tatagtgttg cttatcctta agcatgagct
     1261 cttgctctgc aaaggcaatt tgtgttaggt ctaaatgctc acgatcatag aaatactctt
     1321 tgccatcttt tgtcatcatg taaccaacct taccgccatt ggttaccttg cgactgacat
     1381 gcttagcgtc aaaggacatg tctttaccgt ctgattgaac taatgccctt gcaatctcat
     1441 ctgcttgacc atgctcctgc agccattgtg caacctggtc aagctcctct tgctctagct
     1501 caccaaagcc catgtaatgg aaatgctcct catgcttagc tgtgatgcct gccttatcaa
     1561 cagaggaaat agatgcctta ctaaagacat aatgatcact cgtgtcataa ggcttgccat
     1621 ctaagccttt accataagcc ttaatctgat ggccaaggaa ttgatgtgta acctcttttg
     1681 cagtctggtc ttgagtagct ggctttggct tagctattgg actgccctgc gtttgacctg
     1741 ctaggtaacg atcagccaag gttatttcaa gggctgacaa ttgctcacga ggaataatat
     1801 ggtagtgatc tccatgagga ataacatagc caaaggcatt ggcaagggtc acctgagttg
     1861 gctcaaaaat gagaccatct tcctcgacgt gcctgtattt cttatccaag ccatgcaatt
     1921 gatccaacaa ttctccaaag gttttatctg caaatgatag gcttggatct cctactgacg
     1981 gcaaattccc agctgggtgg tgaatcgggt taacaggaat atcatatggt ctaggctgat
     2041 ctccttgacc tggtaaaggc tgaccgccaa taacacttgg ttttccgcct tgcttgttat
     2101 tccaataggc ctgcgctgct actagctcac ttggggataa gtccttttta ggaatatagt
     2161 ggaagtgact gccatggggc actaaaaagg catctcccat gtctccaata acatctgtcg
     2221 ggctaaagat atagccatca tcagttgtat agcgtccttg acttcttgct tcgttaacag
     2281 ctgccacctc tgccttactc aagtgggcaa ccttagccaa gcctttttcc ttagcttcct
     2341 ttgttccctt ttcaacctgc tcagcaattt gctgcttggt acgaatattt ttacgcttgc
     2401 ttcctggctt tagataaaca taatacttgc catcaacctt gataatatag ccatctagaa
     2461 tctcgttaac aacatcagac tgtttaaact gataattggg gtccgtcatt aatagctctt
     2521 cactaagaat agcatcatag ggaaccttac cattgtagaa atggaaatga tcaccatgtg
     2581 aggttacata gccttgatct gtgattttaa caacgatttg ctctgcagag atcccctctt
     2641 ctgcgctgat ttgatccatt gttttttctt tggggagggc ttttttgcca tcctttgaat
     2701 caatataggc aatgctatta tctttagatg aggaatttag agccttatgc attccaaact
     2761 gatatgaagc agcattagta gccaataaaa tggccacagc tgatcctaaa acaatatgct
     2821 tctttttcac gttttcatct ccctttattt taagctttgg taaagagctt ccaaattagc
     2881 tctcaaattg tctagatagg acttgttgtt tttgggcgct gcctctagtg gactgagcag
     2941 cttgaccttt gctcctgctg ttttagctat cgccttagca attttaggat taacattatc
     3001 ctctgcaaaa atcgttttta ccttatattc tttaacaaag tcttgaattt cagttagttg
     3061 gcgaggagta ggctcttgct ctggcgaaat accagaaata cctaactgct ttaagccaaa
     3121 gcgttttgct agataagaaa aggctgtgtg ctgtgtgaca aaggttttag atgatgtctt
     3181 tttaaacttt ttagtgtact catcagccag ctcttttgct tccttttgga atgcttgagc
     3241 attctcagtg taaatggcct catgcttagg atctaaacga ctgagctcct tagcaatagc
     3301 gagtgcttct tcacctgcta aaataggatc tgtccaggta tgaggatcat acagggtagc
     3361 agggtcaatg ccatctgtca cctcaatatc ctccaaacca gtaacacgat ctaaggttaa
     3421 agatttggaa gcttcaaaaa cagcaacctt tgatttcttc aaattaggat ccaaatcatc
     3481 agcccaggcc tctagggtgt gagagtgata aacaaataaa tcagcatcgt aaatggcagc
     3541 aacgtcattt acagatggct caaaggaatg aatacctgcc cctgactgaa tcatccgaac
     3601 atcgtttagc tcaccagata ccgcctttgt catggcgtaa ataggataaa agctagtgac
     3661 gatcgtcatg cctcttgact gcttgctttg ctccttgggc ttgctacagg caacaagacc
     3721 tgaaaaaaga gcaagcaaca gtgttaaatg tatccatttt cttttcatat aatctccttt
     3781 gctcattaac cagttatgaa ccggttaatt ttaacagctt tagatgtatt tgtcaaattt
     3841 tttaataaaa aataaaagcc attaaaacga tggcttaatc agcccctaac ctgcttaacc
     3901 tttataagaa gccatagctc tatgataaac tgtggtctgt gacgcatgac ctcactgtct
     3961 gttatcttac tgttgcatga tacgtttaaa aaagatttag ccttcttttt ttagattgta
     4021 gaacggcgct gaacaatcac ttaaccgtca aaaaaacgcc ttgatagctg caagacgttt
     4081 ttacttattt ggttttagct agagcgacgt tttgtcacaa gaccgatgac agctgcaagg
     4141 cctattaata gaactcccat gaacgctacc atcggcgctg ctgattcacc agatcttggc
     4201 aaagccttag tctctttttt accttcttta ggggctacat tacggtttga cgaggacttg
     4261 gtttctggct tagcgacatt cttatccttt tcaggatcct ttggctcctt gcctaagggc
     4321 tttgtgtctt tagaatggcg ctcagactcg ctgagtttat tatcggttct gatttgagct
     4381 ttggttaaaa agccgctgac atcactaccg gtagaggctt ttttaggtat cttgaccccg
     4441 ttgataacaa tctcataaaa cataccgtcc atgagctgat tcacaaaggt tgccttacct
     4501 gattgatcag ttttgcctat tgccctgata gctccgtatc gatttttcag cacaacctct
     4561 tgccctgcca acttatttcc attggcatca taaacagtta ctatggctgg tgtcttagag
     4621 taaacaacag gctttgttcc tttaccgtcg acataaaaag cagcagcctt atgctcatta
     4681 gactcactcg tgcgaacagt atagccctgt agcttaccat caattgagac actgatatta
     4741 cgtgatagtg gtagtttggt aaagactgct tgaccatcag catttgtctt tgctgaagca
     4801 attgtcgtct tagcaccgtc tatcagagca gtcaagctta cctccttgcc tgcaacaacc
     4861 ctatcctctt tatctagggc agtgacaaca aaatgaaagc cttcctctag cggacttgac
     4921 tttccatcct cctgcttagg agtgtccttg gactgaggtg acgtacctga tgacgagctt
     4981 gatgaggtat caaggtaagc attaacagac atttttgtca tgacctgccc tatatactta
     5041 ccattaagct cataatgata aaaggttccg tccaacaaac gatccttgaa ggttaccttt
     5101 ccatttttat ctgagacaag acttcccacc agttgaccct gacgtatttt tagggtgact
     5161 gtttgccctt ctaagggctc actatcttga tttcggaccg taatatcaat gacattttta
     5221 ctataaagag gctcctttgt ccctgctccc ttagcgacaa agcttgctgc ctctttagat
     5281 ccagcaagac tggttctcac tgtatagccc ttggtttccc cgtcaacaga aacactcaaa
     5341 ttaatgttta agggtaattg agtaaaaata gcctgaccat tgctgttaga gacagcagaa
     5401 gctacctgct tagcgggatt agctgtcgtg tctaacaaga caactgtttt tccttcaaga
     5461 gcacgaccgt tgctatcaag tatcgtggca acaaaatcaa aaccctcagc cgcttgcgac
     5521 gtcgcagtga caacgttgtc tctggcataa gtcgtatagg tattggcatt ggctgccaag
     5581 gccaagctag atataacagt aaccgttaaa agactgactt ttttcaatga ctgtttcttc
     5641 ataaaaaagc tcctttattt tgattaacta gcctagtttt aatgggaaat atccccttga
     5701 taccctttct gaggtgatag gaacagcagc aatctctctt agcctatgat gcctaagctt
     5761 taaagctaag ttttcaaagt ccacctaagg ggctacatgc cacaacaaaa agcatcagat
     5821 gaacagacat ctagaggcaa cagccgatct aagataatag ttagtagcca ttttagctac
     5881 tctcaaggct gtcgccgcag tgatgatgtg attgtctatg ctttttaata aaacttaact
     5941 agttaagatt tttgtgctgc tatcctatca aataaccccc gccaagtcaa caacaatgct
     6001 cataccacag caagcaaagc attttgatga tgactgaaca gccaaatcag ccaagcccca
     6061 ggcagcaaaa aagaggattc aaaccaaatc ctctctctac taagcctgct gctgttaacg
     6121 tatcatgcta aaggcaaatg gtatagccac gctgatatga aggtctgatt aacagctacg
     6181 acggacacgc ttgttaaggc taccattgct aatcacacta ggtcatatcc tccaccgtat
     6241 aagaatgact aacttcatta ttcagattaa cgatatacct gcaggtgctg aggaagtacc
     6301 ttgacagtga ttggtaaggc ctcaccctca tcaccgtcca cattgataga tagctgtcct
     6361 tccttcatgg caatagtggc ctccttgaag gtttgatagc caagtgtttg atctgaagcc
     6421 tcaactccct tcaataggct aggaagggcc ttcaccgttt ctaatagatt gctatccttc
     6481 agatagataa ggtgcagcaa accatcgtcc acacgtgcct ctggcaaaat ccgctcaaag
     6541 cccccgattg aattggtcaa gccaatcaag agtgttgtgc tgttgatttc ttttgttttg
     6601 ccatcaatat ctagctggaa ggtatagctt ttatttttga tcagctgctt aaagcctgac
     6661 ataaaataag ccattttccc aaaggtcgtc ttctcctcag gggcaacatc attgatcgcc
     6721 tctgggagcg tccctatggc aacaacattc ataaagtaag catcgttgac cttaccaata
     6781 tccagaggac tggttgtctc aaagcttatc tgattaatcg cttcctctgg gtctaacgac
     6841 atgcccaagg cacgtgccaa atcattgact gttcctagag gaaaaaagcc aaacttaggg
     6901 cgatagtcct gctctgcaag cccgctgatc ccttcattga ctgttccatc acctcccatg
     6961 acaaagacac tgtccagccg ctgctgggct gcctcatgag caaaccgttt ggcatctcct
     7021 cctttttcag tgtgcttaac gtcaacatca tcaaaatacg aagctagttt atcataggct
     7081 aaggcttcat attccttggc tttctcacca cctgagctag ggttaacaat caatagggct
     7141 tttttcattt atgatatcct acattttcta ttatatttca cgactattat aatcattatt
     7201 caaaacatcg tcaaataata ctcactatgt cattagtcag tcttaaagct tctaatatgg
     7261 ttgccgtcta gtgtttcatt ttactgaact ctttacccag ctagctcaat gcctaaccaa
     7321 tcgtgctgtc tcttaaggtc aactctgtcg ccaatatcgt catggtcttg acacgttctg
     7381 ggttaaggat attcctatta agcacatcaa cagccatacg tcccatatcc tctgtaaata
     7441 cagtcacact agaaagcgca ggaaagacct gtcttgttaa aggagtatcg ttaaaggaga
     7501 taagctcaac acgctcaggc accgcaagcc ctctttcttg gagagctctt agagcaccta
     7561 ttgcaagggt atcattagca ataaaaaatg ctttaggcaa atcatcacct agctcctcaa
     7621 ttgcctgtgt cataagctca tagccagatt gtgctgaaaa aggaccgata tagacatacc
     7681 tcggctgata aatcccatgc tcagaggcat aatttttata ggtgcgaaag cgctggtcca
     7741 ctaaagcttc tctaccgtca gttgtctttt cctcaccagc aatcatgcca atgctataaa
     7801 tccctttgct cataaaataa tcaagaactt tcagcactgc attgtcaaag tcagttgtga
     7861 cacaggggtg gcccaattca agcgtgtcac tatcaacaaa caccaaatgc tgggataagg
     7921 cttcaagctc cttgatttga caagcgctaa actttccaat agcaataatc ccggcatggt
     7981 catctgaaac cctcaaaatg tcattgttga aataacgaac aatatcataa tccaattcat
     8041 aagctctttt ttcaatgcca atgcggatcg cataatagta gaggtcattg agctcctctt
     8101 cttgagaata ccattgaaca atagctattt ttagctttga tttagggcta ttcgtcgctt
     8161 ttaaatgctt ttggtagccc agctcatcag caattgtgag aatgcggtgc tttgtctctt
     8221 gaccaacaga caagctttgg tccttattta aaactctaga aacagttgca ggagaaacct
     8281 ttgccagagc tgcaatatcc ttaagcgtta ccatatcaaa ccttctttct gatttcttct
     8341 agtatatcac aagcattttc aaaagcaata tttagtaaaa ttttagtaaa aatgttgacg
     8401 agcagcttag cgaagcgtaa aatcaagcta tcaacatcgt taaaggagcc gctaatggat
     8461 atcgcgcaac ttaagcaaag ctttactgac gtttttggca aggagccaga tgctgtcttt
     8521 ttctcaccgg gtcgcatcaa cctcattggt gagcacactg attacaatgg tggacatgtc
     8581 tttccagctg ctatcagtct gggaacctat gggctggccc gcaagcgtga ggatcagcag
     8641 ctgcgctttt tctcagcaaa ttttgaagag gctgggatta ttgaggttga cttaaatcag
     8701 ctgacctttg atcaggctga cctttgggct aattacccta agggagttct ctcctttttg
     8761 caaaaagctg ggcaccttat tgatacgggc tttgagcttt acgtttttgg caacattcca
     8821 aatgggtctg gtctgtcctc ctcggcatca ctggagcttt tgacaggtat tgtggcacaa
     8881 gagctgtttg ggcttgatgt ggaacggtta gatctgatta aaatcggtca gcaagctgaa
     8941 aatcacttta tcggggtgaa ttcaggtatc atggaccaat ttgccatagg catgggagct
     9001 gataagcagg ctctatacct tgataccaac accttagcct atgaggctgt tccgcttgac
     9061 cttggtgatc acgtgattgt catcatgaat accaacaagc gccgagagct agccgattca
     9121 aagtataatg aacgccgagc agagtgtgaa caagcccttg aggaattaaa tgcccttctg
     9181 gatattaaag cactggggga attagacgct cagcgctttg atgagtacag ctaccttatc
     9241 aaagatggta aacgtctcaa acgcgctcgc cacgctgttt tggaaaatca acgaacactc
     9301 caagcaagac aggcccttga agcaggagca ttggagcaat ttggtcgtct gatgaatgct
     9361 tctcatgtat ccttggagca tgattatgag gtcacaggcc ctgagctgga cacactggtc
     9421 cacaccgctt gggagcaaga aggggtccta ggggctcgca tgacaggagc aggctttgga
     9481 ggctgtggca ttgctatcgt ggctaaggat aaggtagata gctttatcga aacagttggc
     9541 aaggcctata ctaaggtcat tggctatgct ccagcctttt atctggctga gattgctcag
     9601 ggagcacgac tactttcaag gaaataagat atggcaagct taatagacac ctttgtaagg
     9661 aaggtgattg aacacagcga ctacacatca gaggacgcta tttatatccg caatcgggtt
     9721 ttagcattgg ttggtgagaa ccatgtctgg caagaaacct ccttaacagc cttaatagct
     9781 ctcaaagaag cattggttga gctagctgct gaaaatggca aaataggcag gcttcctgaa
     9841 gaaaaggact gcttaggagc tgaattaatg aacatgataa cccctattcc aagtgtggtt
     9901 aatcgtcgct tctgggatac ctatgcacaa tctcctcaac aggctatctc agatttttac
     9961 cagcttagtc agctaaatga ctacatcaaa acagcagcaa ttgccaaaaa catctccttt
    10021 acagtgcctt ctcaatatgg tgatatggct attaccatta acctatcaaa gcctgaaaag
    10081 gaccctaagg ccattgcagc cgctaagaag gctaaggcat cctcttatcc aaaatgccag
    10141 ctttgtatgg aaaacgaagg ttatcaagga cggattaacc acccagcccg agctaatcat
    10201 cgcattatcc gtatgagctt aggcaatgag gcttggggat tccagtattc accctacgct
    10261 tattttaatg agcacagtat tatttttaat actgagcatg tgccaatgac aatcagtaca
    10321 agcaccttta gacagctcct tgatattgtt gatatcctgc cagactattt tgtcggctct
    10381 aatgctgatc tgcctattgt tggcggctct attttgaccc acaaccatta tcaggccggt
    10441 cggcacgttt ttccgatgga aatcgcaaaa caagacaaac gctttacctt taaaggattt
    10501 ccagacatac aggctgccac tctcaactgg cctatgtcag ttatccgact gcgcagcagc
    10561 aacaaagatc agctagttca attagcagac acgattcgac tggcttggcg tcattattct
    10621 gacgacagtg ttgatatcgt cgcttatacc aaccaagagc ctcaccatac catcacacct
    10681 attgccagaa aaaaagaagg gcagtttgaa ttagacttgg ttctacgtga taaccatacc
    10741 tctgagcaat ttccagacgg tgtttaccac ccacatgccg atgtgcaaca cattaagaaa
    10801 gaaaacatcg gccttattga ggttatgggg ctagctattt taccaccgcg cctcaaagag
    10861 gaattggttg aggtcaaaaa atatatcctc aatcaagcca atcaaatcgc agactaccac
    10921 aaggactggg ctgatcagat cacattacga ccagatctct cagcgataac tgttgatgac
    10981 attatccaag aagaggtcgg ctctgtcttt gttcgtgtcc ttgaggacgc tggcgtctac
    11041 aaacgtgatc aagaaggtca agcagccttt atgcgttttc ttaagagcat tggcattgaa
    11101 gcaattgaag aataggagga aaaaatgact gttctagttt taggcggtgc aggctacatt
    11161 ggatcacata cagtggactg gctaatatca cagagagaag aaaaagtcat tgttgttgat
    11221 agcttggtga cagggcaccg taaagccgtt cacccagagg ctctgtttta caaaggagac
    11281 ttagcagaca aagcctttat gcgtcaagtc tttagggaca atccagacat agacactgtg
    11341 attcactttg ctgcctcttc cttggtcgca gaatcaatgg cagaccctct gaaatacttt
    11401 gacaataaca cagcaggtat gattaagctg cttgaggtca tgagagaagc caaggttaag
    11461 cgcattgtct tttcatcaac agcagccgtc tatggcattc caaaaacagt ccccatctta
    11521 gagtcagcgc ctaaatgccc aatcaatcct tatggccaaa gcaagcttat gatggaaacg
    11581 ataatgacct gggccgacaa agcctatggc atcacatttg tggcccttcg ctacttcaat
    11641 gttgccggag caaagccaga tggctccatc ggtgaagacc acgagccaga aacacattta
    11701 ttacccatta tcctacagac tgcacaggga gtgcgtgagc aggtgatgat ttttggtgat
    11761 gattatgaca caccagatgg tactaacgtt cgagattacg tccatcctat cgatttagct
    11821 gatgcacaca ttttagcgat ggcatacctg cgtcagggca aaccatcaca ggtctttaat
    11881 ctagggtctc aaacaggctt ttccaatcgt caactgcttg aagccgctcg tcgggtaaca
    11941 ggacaagcca taccagccaa aaaagctgca agacgtcccg gtgatccaga caccttaatt
    12001 gcgtcatcag aaaaagcacg caaggttctc aattggaagc caagctatga cgatattgac
    12061 aagataatcg catcagcctg ggcctggcat accaagcatc caaaaggata tgacgataaa
    12121 gcaagtggca gctagtccct caagacagct accacagcaa gtagtcagcc tcccttaatt
    12181 catacaccta tactaatagg agaaacaaac tgtgaacatt tatcaagaca tcattgaata
    12241 catcgatcaa gtgccagtca cccagctaag actgattaat actaacggtg ttgaggctca
    12301 cctattgaca ctaggagcca ctctacaggc ctttctagtg tcaaatgaaa agcagccaaa
    12361 aaatatcatt ttgggacatg accgaccaag tgactaccta aaaaatcctc tttgtgcagg
    12421 gcaaaccatt ggccgagtag caggtcgcat aaagagagga agctttcagc tagagcagca
    12481 aagggtttgt gttgacacca atgaaaatgg gcattgcctg catggaggct tcaagggctt
    12541 tcataagctt cattggcctt atgatacccg ccaaacagtt gattaccttg aagtaacctt
    12601 taaaagggat attttagaag cagatgacca tttcccaggt gacctgaccg taagcattac
    12661 ctaccgtcta gacaaccata atcgtttaag cattcacttt aaggctcata gcatgagagg
    12721 cactagccta ttcaatccaa ccaaccatgt ttattttaat ttagggcaaa cacaagactt
    12781 aaccaatcac aacctataca tcgcagcatc acataggatt gaaacagata atgagctaat
    12841 cccaacaggt caaaagctag cagttgacca gacggtctat gattttagat caataaagtc
    12901 cctctatcct gctattgtcg aaaataatgg ctttgatact gcctttgaaa ttgatcagca
    12961 ggctattgga acaaccaaac ctattgctgt cttacaagac agcgtcagcc atgaccaaat
    13021 cagcatctac tctgaccgaa acgcactcgt catttatacc atggacagta tccaagatgg
    13081 cttgtatttt ggaagagatc agggcaagga gggactggct cgtgagggga tcgctatgga
    13141 agcacaaacc ctgcctgatg ctattcacca caaccagttt ggtgacatta tcctcaaaga
    13201 aggaggcacc aaaagctaca ctatctgcct agcctatgag catctgccag attaacataa
    13261 gtacagccaa gctttaatga aataacaaga ccttgatttt tttgaattgc accccaaccg
    13321 ttagccaaaa actctaacaa gcgaggatca gttcattcat caaggtcttt tcctcttttt
    13381 atctataggc gttacaaagt agatatagga acatcatacc aaatatgtgg aatgctaaga
    13441 gcttatcatc acaaagcgaa tacatgttcc gactacatct atgcattagt aagtcttttt
    13501 cctaaacgaa gtgttgccag ctttatgaga tacttaaaag tataagagca gcctaatcat
    13561 ttttgacaaa gacaccaacc ttaagcataa acataggcat cagaaatttt ggtatatggg
    13621 ctattatgga gacacagctg gtaaaaatct aaaaacgata gccaaatata tttcaaatca
    13681 ctataggaag atagggtagc aaaccaactg acatcatttg agaccattga tccatttaca
    13741 ggccaaccaa ataagaaaaa gtaacctttt gattgaactc ccgctcggaa aagtggagcg
    13801 cgagtattca atgacctcgt tatcctcgac cgatgagagc agcttatagt cacagtataa
    13861 agaggctgga acagacaacc tcttttgatt gacaataagt gtttgatagc attgtatggg
    13921 attactttca catcattcag cacctgggtc gagctttgat gaccgccaga attgatagcc
    13981 attatgaagg gctttgagca gccatttctg ctttatcgaa ccataaaata tcattgatga
    14041 ctgctccaaa aggacagtca taaactgtct gatcagcgct tctagtcacg aacctttaag
    14101 caaaccttaa tactcaaaaa aggtaagtca gaaaatactt gatttctcag atgagctgtg
    14161 gaattaccac gacctttacc agctcttgct ctttcatttt caaaaagtgg gtaaccgagt
    14221 ttttcgggct gattgaagag ctttaagctt ggtcaatcat cacgttttaa ccgtcctcaa
    14281 aatctttttg aaatacaaac cctacatcac aaatgcctta ttccaatgct aaattggagc
    14341 ccactaacaa gactattaag gacatgaaag agcaagcctt tggatttagg aactttaaga
    14401 acttcaaagt caagattccc aatgctttaa acatcacaaa agaagagaca aaatttatct
    14461 cttctcgtgc ttagctatca gtcacccact gcagttgaca ttgagccaaa ttatagagcc
    14521 attttcgtag aaagcacaga aaaaacaccc atgaggtaaa ctcttgagtg ctttgaaacg
    14581 ttgatataat gcgatatatt aacgttttga ggcacggaga ctgcgtctcc tttgcagccg
    14641 tattcgtaag cgactaaagc cgcaacgact acgtcaattg cgtcgccagt tctttcaaaa
    14701 aagaaaatac cccatggtaa cccatgaagt attgttctgc tgtattgtag ctggttctta
    14761 acgttttgag aactgactag ctttacgagc tttcttaaga cctggttttg ggtgacaaaa
    14821 accaaatatc tgtaaaagct tatcaaatca agctttcaaa actcattttc attaaatata
    14881 agcactttta acccaatcct acaaataata gattaccatt agattaccaa aactcagttt
    14941 tcggagctta tgtagttgag aaaatctcgt atttactttg cttttatata tccactttat
    15001 actatcatcc cgtcataaca gagcatgatt aaatagttac ataaaaaaca atacttactc
    15061 tatcattaaa ggatattgtt aaaaagattc tctaaatcat ttaaataatc agttttagta
    15121 cttctaatac gaagaatatc tacccttgac tgacgaatta aataaaatac tatgaaatgc
    15181 ttactaggaa tcatccttag ctggccttca ggaaatagtt tacgtcctac acgatcgtca
    15241 aaatcaacat aaccttcagg ggatatctca agaatagaaa tagctgactg caaagattca
    15301 ataacttttt gagcgcttga gtgcgaaaat tctgttaaat agtagttata gatttcatct
    15361 aaatcttgtt ctgccttatt tgaaatatag atatcataag ccatattttg aaaatacctc
    15421 attagctggc ttcgtacgtc ctgctaaaat atcttgatac ccttcatcaa gctctgatat
    15481 cagttcattt aaaaatgatt cagctctaat ttgttctgca gttttaatag gtaaatcttt
    15541 ttcttccacc acccgttcaa caaatagatt aagagcatct ggaacactaa tatttttagc
    15601 ttctaaaata cgctttgctt cttccatcat ttccgtattt actctaaaat tatactgtct
    15661 atctcttatt aatgtagcca ttatagtctc cttaattgcg ttatccttat gtataacaag
    15721 attataacaa atcaata
//
LOCUS       DARYVE010000050        15637 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYVE010000050 DARYVE010000000
VERSION     DARYVE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15637
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..1031)
                     /locus_tag="TVW25_001479"
     CDS             complement(<1..1031)
                     /locus_tag="TVW25_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379098.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1037..1891)
                     /locus_tag="TVW25_001480"
     CDS             complement(1037..1891)
                     /locus_tag="TVW25_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379099.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1958..2158)
                     /locus_tag="TVW25_001481"
     CDS             complement(1958..2158)
                     /locus_tag="TVW25_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1379100.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            complement(2531..3268)
                     /locus_tag="TVW25_001482"
     CDS             complement(2531..3268)
                     /locus_tag="TVW25_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1379101.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            complement(4019..4324)
                     /locus_tag="TVW25_001483"
     CDS             complement(4019..4324)
                     /locus_tag="TVW25_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1379102.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            complement(4326..4664)
                     /locus_tag="TVW25_001484"
     CDS             complement(4326..4664)
                     /locus_tag="TVW25_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1379103.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSPGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(4692..5447)
                     /locus_tag="TVW25_001485"
     CDS             complement(4692..5447)
                     /locus_tag="TVW25_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1379104.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            5708..6163
                     /locus_tag="TVW25_001486"
     CDS             5708..6163
                     /locus_tag="TVW25_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1379105.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            6147..6797
                     /locus_tag="TVW25_001487"
     CDS             6147..6797
                     /locus_tag="TVW25_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1379106.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            6907..7811
                     /locus_tag="TVW25_001488"
                     /pseudo
     CDS             6907..7811
                     /locus_tag="TVW25_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(8164..8439)
                     /locus_tag="TVW25_001489"
     CDS             complement(8164..8439)
                     /locus_tag="TVW25_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379107.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(8862..10412)
                     /locus_tag="TVW25_001490"
     CDS             complement(8862..10412)
                     /locus_tag="TVW25_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1379108.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(11083..11643)
                     /locus_tag="TVW25_001491"
     CDS             complement(11083..11643)
                     /locus_tag="TVW25_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1379109.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(11621..12490)
                     /locus_tag="TVW25_001492"
     CDS             complement(11621..12490)
                     /locus_tag="TVW25_001492"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1379110.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            12582..13853
                     /locus_tag="TVW25_001493"
     CDS             12582..13853
                     /locus_tag="TVW25_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1379111.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(13889..14227)
                     /locus_tag="TVW25_001494"
     CDS             complement(13889..14227)
                     /locus_tag="TVW25_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379112.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(14327..15415)
                     /locus_tag="TVW25_001495"
     CDS             complement(14327..15415)
                     /locus_tag="TVW25_001495"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1379113.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         4830 a         3442 c         2720 g         4645 t
ORIGIN      
        1 gccaatttta ataataattc ttgtgtacca aaggtttgta cggatacaaa tgttaacagt
       61 ttgttcatca aaccttctgg aaaaattccc attagaaaga ccggtgcata tacaataaga
      121 gcagatatac caaaagtggt tagaggagac ttagttagag atgaaactag tgcatgaatg
      181 cctgtcataa atatcaggcc aatatactga aacaccaata aatagacaaa cgcaatgcct
      241 aaggtcatct tttccgggaa agccataatg tttatcactg gatcaatcca atacaaattg
      301 agttgtaagc tagtgtccca gccgctaaaa ccaaaatagg tcgcaaagac agcaaagacc
      361 agaccactag caattgcaaa taccaaagta ctgacagcta tgctaactgc taatttagca
      421 agagtcaatt taccacgtcc aaaaacagtc gtcaataaga tagagttcat ctttttagat
      481 gattcccctg aaaataaagg agccgttata taaagacaaa gcataacaac aagaagataa
      541 gtactattgg ttacatcaaa caactgattc caaggagcaa aattacctaa cttcaactct
      601 ttcaaaggca gagcggaccc caactcttca cgtgatttga gatgaacatt gtcaaatgtc
      661 agagacttat cagtgctatt aatagcgata agcttatcag tagacttagg cactaaatga
      721 gagatagcat aatgtgatac cacactatat acacccttct tttttaggtc tgattgattt
      781 ttagcataat cattgaggat acgactaatc agatcgtcag ataaataacc tgtatgcttc
      841 tcagcaattt gttggttaat tgctacagct gcacgtccat gaacctgatc tgcagaagag
      901 ccactgatct gaccgttaaa aaaatgctgg taaaaaagac cacctacagc caataagacc
      961 actacaatcg caccaaatac cgactgtcgt cttaataatt ttttaaactc aaagggtatg
     1021 agagatgcca tagaattcac tcctttctaa aatgataaat gtagagatcc tctaatgttg
     1081 gtgacacagg atttgcctga taacaaggac tctcatcgct cacaacacgt aagatacgat
     1141 tattttttac aattttttca ttgacaacgg catagtcagt caaaaatgct ggtgcactct
     1201 ctgtagcaac aggaatctcc cataccttgc cgatcattgt ttgaactaac tgatcaacac
     1261 ttcctttttc tataaactga ccatgcttta gaaggattac ctcctttgca accgcttcta
     1321 catcagatac aatatgtgtt gataggataa taattttttg ctctgataaa tcactgataa
     1381 tatttctaaa ttttacacgt tcctttggat caagtccgac tgttggttca tctaaaatta
     1441 acagtaaagg atcgttgata agtgcctgag caatacccaa tcgctgcttc ataccgccag
     1501 aataagaagc aattttcttt tttctaacat cataaagacc taccagcttt aataaccgat
     1561 cagcttctac taaagccttt ttacgtttaa cattcttcaa agcagccata taaagaagga
     1621 attctaaacc ggaaaactgc tgataataat taaactgttg aggtaaaaag ccaatattct
     1681 ggtaaaagtt ttttggttgt tgttgatgat ttaaactaat ttctccacta tcaggaactg
     1741 taaactgact aatgatgttt aataaagtcg ttttaccggt cccatttgct cccaataacc
     1801 catacaagcc tggtgtaaat tgtgcagaaa tacgactcaa caccttttta cttccataag
     1861 atttagaaat attatctagt attaacaaca ttgtcattcc tcctaagtaa aaacccaggg
     1921 aacagcacca cttcgctgct ccccagatga ttaaccatta agcattatat actcgacaaa
     1981 cggtaccagg ataaagaatc atgtggttat cagcattttc ttgtgctgta tctcttaata
     2041 gatgccatgc acttgtataa ccatcagtgc atctccacct ataaccccaa ccaccttcaa
     2101 cgcctgcaag catatcagca gtcattgtac taaattgttc aattgttttt gtattcatat
     2161 cgaatacctc cttataatga ttttatctag ctacagtctc gacaaactta gtgtagcgct
     2221 ttttaaagca acgacactca aaaatcttga atggttctta ttttgtcgtg aatggtcaat
     2281 ttttcttctg aaattaccag ttaagatcat atggatacct ttcacgagct atatcttttt
     2341 ctctcttttc ttatgatata attgattttt gcatgtacat catatctctg agcatcatta
     2401 gaaaccaact gttacccctt tttcttagtt ttgactaaat atatttataa taaatatccc
     2461 ttaaggtaaa tggtatcaac gaggttgatt aaaaaacaaa tgatggcttc cacatggcat
     2521 tcttttactg tcaatgcaaa gccttaatag acgcctcaag tgctttcatt tttagtcttg
     2581 aaaccatgca agactgccca ttcttgaaat agagtaaacg cttatcacga tcaagaaacg
     2641 aaacattgta aggattgata acataagaac gatgacattg gactagtctg gaatcttgct
     2701 taagaacctc tgaaagaaag ccataaaatt ctattcgctc gttttgagaa tgcaaaatca
     2761 acttgtgagg agtactagag gtctcaatga acaataggct tgaaaaagga acctgcacct
     2821 gagccttagc cgttgcaaaa ataaataagc cctctgaggt tacattttct tgctcttcat
     2881 aagcatatat aatggctctt tcaatcctat ctgagaaatg tttcattgac aattccttat
     2941 cgataaaatc tagagcagac acctgataac gaaaagaaac tggcataagc tcagaatgtg
     3001 tggtgacaaa aacaatgagg gcataagggt cacgctttct gatctcacga gcaacagcta
     3061 agcccttttt ctcatcattt cgaatttgaa tatcgagaaa gaaaagctga tgcctgcctc
     3121 tctctgtaac atttgccaga agctggtagg gctttccata aacttcaaaa cgatcacaag
     3181 tccagtgatg cttatccaat atctcttgaa tcttcatctc aagcctaaac tgttggccta
     3241 gatcatcttc gagaataaaa atattcattt agaacctcct tattgcttta gcttatcgtt
     3301 tttttaggag actaaagcag ctttttgaac aagtgatagc tagaacgctc tccttcatga
     3361 acagtatctt tttagcatca ccattaaaac catgaccgtt aagcttatta actaaaggtt
     3421 gtcaatgact tctaaccaac ttgtcattgc agcgttttca ataggcctta gcgaatcacg
     3481 cgcctcaaac aattttttta ccacagataa tatactagca cgagccgcaa gtcatacctc
     3541 tttgagagag agctcttaac gactatcact tttgtttgac aagtcatcag ctatcaatcc
     3601 acacactgat ctccttgcac agacattcta acacaaagct agggagcagg gagttaaaat
     3661 cttaaatggt actgattatg tcttaaatgg taaataagga aaactaacaa tggctagtca
     3721 ggttactgag gctatctgat gattagctgc ttgtagctat accttctcca agcaataagt
     3781 ttctagaatt attggtaaca aatacattag gtatccggga tattctgtca tttattttat
     3841 cataaaaaca atctttttat catcaaaaca ggtaattgtt attattatta atcactttga
     3901 gtgatttgaa gtaagctaga tcttcagcta aaccttatga cactaaacac aaaaagcccc
     3961 ctaaggcagc taaaacacca gcctaggggg caagattcaa gagagtcact ctatactttt
     4021 agaccatttc aatttgcagg tatttacaat ttgttgcagc ctctaaatga taaaactgat
     4081 gagcagagat actgatcaat ccgcctgctt tcatgtcatg agcctgatcc gtaagactaa
     4141 ccagcaacct tccttctaag acaagcagga gcttaccttc agggcttgat tcgttactaa
     4201 tcgtctctcc ctgatacatg gcatataaaa caacagattg cttaaagcct aggctttgat
     4261 gaagcgaacg actagctatt tggtcatcat gataccttac taattctaat aaatcagcca
     4321 acatgctaag cctccggctt tacaacaact aaaagcatct ggaaggcttc cttagcaaat
     4381 aagctatgag gaatattagc aggcatgatg atcgtctcgc cagcagctac ctcataacag
     4441 gcttctccaa tagtaatgtc aactactcca cttaacacgt taaccattgc atctcccggt
     4501 gatgaatgac gaccgatttc ttgtccttta tctaatgaaa acagggttat gcccaaatct
     4561 tttctttgaa ctagtgttcg acttaatatt tgatcctctt caattggcac ttctgccttt
     4621 aaatcaatga ctgtgcttgt tggaatttta cgaatcaatg acatgtcact tctcctttac
     4681 cattattcta gttatttttg acttacagcg gcaatataac acagctttct tccagttttg
     4741 ttgaagaaat gacgcatctt taaaaactgc tttcgatttt cttttttcat gccgcgcagc
     4801 ataatacgaa tcgcagcgac aaccccttca tctttaatca tgccaagcgg ggacatgagc
     4861 gtcatattac cataggagta attgactgct gtgaagccac tctttaccag caattgtctc
     4921 caggcatcta actgcaatgg cgatacgttc acattaatcg tatctcttag ttgctctata
     4981 atagcctttg tttcatcagc ttcataggaa acatcatgcg ttagtaggcg accacccggc
     5041 tttaaaacac gccaatattc cttaagtgct ttttcctttg cagcatcatt caacatggtt
     5101 agcatagctt cgttaataac gatatcaaag ctattatctg caaaaggcag cttcaaggca
     5161 ttagcttggg taaggtgaat atagtcttgc atttgtgctg cctcaatagc ctttcttgcc
     5221 tccgccagta ccttggtatc caaatctact gctgtaatat gacactgata agtctgcgcc
     5281 agctcaatgg aggtcgtgca acggttgcag gccacttcca agaccttgca atcactcgaa
     5341 aactctcctt gctgaaccag ccaattcgtc gcctcaacac cgccaggccg tagtcgtttc
     5401 tttcccagtc gagctaaaaa ctggtgacca acttcttttt gagacatcac atgccctcct
     5461 atttgctctg ctatatatca tcacttagaa taaactaact gttaacaaat tgatcaataa
     5521 atgattacta caactatatc acacttaaag catatcctca atgaagctta agcatttctg
     5581 atgattgttt ttatgataaa tcatagaatt ggctcatatt tcttgtgcta tacgaccttt
     5641 tgacttgcta ttatttttta aataatatat aatctagtta tcaaaactag ataaagaggt
     5701 tttagtaatg gaatatgata agctgcccag ctggaaggat ttacctgatt tggagttata
     5761 cttagatcaa gtgttactct atgtcaatca ggtcacacaa ttgagtcaag ccacagacca
     5821 taagctactg actgcttcaa tgatcaataa ctatgtcaaa catggctata ttgataaacc
     5881 tattaagaaa aaatatcaaa aaaagcaggt tgcccgctta attgctatta gcattttgaa
     5941 aaatgtattt cctattcaag atattagtca ggtcttgacg agcctacaag cagcctccag
     6001 ctcagaggtc ttgtacgata cctttgtcaa ctattggaat aatggcctta cccaatcaac
     6061 gcctgaaatt attagctatg cttgtcaaac cgtcaaggac tatcagcaca caatgaagct
     6121 ttcaagagaa atggaggata ccaagcatga accaaacctt taaacaaagt ctcccactat
     6181 cagttaatga agaggtcgca aatagtgtga cacacgctat tggagcagct gctatgctga
     6241 tactgctacc catcactgct atttactctt accagactta tgatctcaag gctgccgttg
     6301 gagcatctat ttttatcatc agcttatttc tcatgttttt atcatcaacg atttaccatt
     6361 ccatgtccta tggaacaact cacaaataca ttttacgtat cattgatcat agcatgattt
     6421 atattgctat tgctggtagc tatacacctg ttgccttatc cttggttgag ggcttgttgg
     6481 gctatgtgat tatcatactc cagtggggaa tcacactttt tgggattttg tataaaattt
     6541 ttgctaaaac gattaatgaa aagttcagtc ttgcgcttta cattattatg ggctggttgg
     6601 tcgtttttat cctgccggtg attatccaaa aggccagtct gccatttgga atcttgatgc
     6661 tactaggtgg cttatcctat actgtcggcg caggctttta tgctaaaaag aagccctatt
     6721 atcacatgat ctggcacctt tttatccttt tagcctctgc tttacaggtt attgccatta
     6781 ttttctatat gctgtaaaaa gtagctgttg ctacttttta aacgcgagcg cttgcttacc
     6841 cccagacacc tggcttgatt catgctataa taaagggcag taaatagttg aagggatcaa
     6901 agcaatatga aaacggtaca tattttttac aatcctaatt caggaaaacc agaaaatgac
     6961 ctggctgaaa aggtcaagca ttatctgatt caaaatggtt tttctgaaga caaggttcag
     7021 attattaccc ccaaaaatgc tgatcaagcc tttcaattag ccaaaaaatc ctcacaggat
     7081 catattgatc tagtcattcc tctaggcgga gatgggacac ttaataaaat tattggaggt
     7141 gtttatgaag gtggtgctca ttctgttatt ggactcgtac cgtcgggcac tgtcaataac
     7201 tttgcaaagg ccttaaacat tccactccag ctaactgagg cacttgagac gattttatct
     7261 ggcacgatta aaaaagtaga tatttgcaag gtaaacaagg gctatatgat ttctagccta
     7321 accttgggtc tgcttgctga tattgcggct aatgtgacta cagaagaaaa acgaaaattt
     7381 ggcccttggc ctttttaaag gatagtatta agatactaaa acgaaaccgc acatatgcaa
     7441 ttagcttaat tagccatcat catgttcttc acttgaaaac caaattctta ttgattacca
     7501 caaccaatac tatagcaggt cttccatcgt tttcaccagg tgcacaagct gacgatggct
     7561 tgtgtcaagt ttacacgatg agccagctat catttctgaa atgcttgcgc catattagag
     7621 actttagacg gggggatttt tccaaggtaa aggagattag ccattttcaa gctgattctc
     7681 taaagctatt gccacaatat cagcgtcaat cagccattcc tagaactcgc attgatggcg
     7741 ataaggctga tgatctccct gttgaattga aggttattcc aaaagcgatt tccattattg
     7801 ttagccagta aaaaagtgcc ctagggcact ttttgatata gattcatctc caagctgagt
     7861 tttagaaaac taagctatag ctataacgtt agctgtggct tcttcttgct ggcttgcagt
     7921 actcttttct tgtcttaaca gctagctctt tcataatatc ggctttaaca aagaagctat
     7981 ctgactagtc cgatcttcta ttctcaggac aaacagcgag aaaggggatt ttctttgaat
     8041 cctagagaac cttagctatc tctgtgtctc attgtaagtg cagctctatt gactgatgcc
     8101 agctatagca ataagcccag tcgcatatta taaaggatta tcaggcgatt tagcttgaca
     8161 ctcttatatc tttattgctt cttctaaggt tcctttaata gctttagctg ctgaatgacc
     8221 acaggcatta gcagcaacct tagaggcttc taccttatca gaggctgtct caataagttg
     8281 tccacccttt tcttggatat aatggttcaa ctcctcaata gtttcagagc cttcctttaa
     8341 gagctctttc tttttggctg aggataagct taaatatgtc acagcaattg ctgctgaacc
     8401 aagaagtaat cctaagccga ttccatagct ttttttcatc atcaacccta ctttctatga
     8461 ccttccttaa tcatcttttt agctaatttt acagctggta ctactaaaag caccaattgt
     8521 aaaagatcca tatacttgat ttttcgtcgt tttttcacca tgtgctattt cctttttctt
     8581 gtttgcacca tacaatcgtc ttttattgcg cagtgccaga gactgcctga ttaggcagcg
     8641 taagctaaga actatcagcg tgtcagacta gtctagatac agctaagcac tagcttgatt
     8701 acgataatac ttaccgctag gccataagct cagctatcat caaatctaaa gtgacaacgc
     8761 tttttattta ttatattgtc attttactaa aatacacaat tatcgtcaat gcttttgctt
     8821 taggcagcaa aaatgcccaa gataaagacc ttggacatct gctacaatga cgttaattga
     8881 ttgaaatccc aaatatcagt tacccagccc tcataaaact ccggctcatg gcaaaccatc
     8941 aaaatagagc ctttatagac ttgcaaggcg cgttttaact cctccttagc atctacatct
     9001 aaatgattgg ttggctcatc taggattaaa acattgtgct cacgattcat taagagacaa
     9061 aaacgaacct tggcttgctc accacccgag agcccctgaa tctggctttc aatatgctta
     9121 gaggttagac cgcaacgagc taaggctgcc cgaacctctg cttgatttaa agcaggaaaa
     9181 gcgtcccata ctgcttctag tggcgtttga cgcttaacac ctgcagtttc ttgctcaaaa
     9241 taaccaagct ccacgaaatc tcctgtttcc acctctcctg acagtggctg aataatgcca
     9301 agcaggctct ttaggagggt tgacttacca ataccattag caccgataat tgcaactttt
     9361 tgatgacgct caaatgttaa gttcaaggga tcttttgtta ggggtctgtc atagccgatg
     9421 acaagctccc ttgtttggaa aataaagcgg cttggtgttc ttgcttcctt aaactcaaag
     9481 cttggctttg gtttttctgc ctgaagctca atgatttcca ttttatcaag cttcttttga
     9541 cgggacatag ccatattgcg agtagctact ctggccttat tacgattgac aaaatcctgt
     9601 agctctgcaa tctctttttg ctgacgctca taggctgcct ctagctgagc ttttttcatc
     9661 tcatagactt ccttaaactg atcgtaattt ccagaatacc taaccaaatt ccgattatca
     9721 acatgataaa caatattaat gacatcattt aaaaaaggaa tatcatgtga aatgagcaca
     9781 aaggcattgt cataatgctg taaatagcgc tttaaccact caatatgctc agcatcaaga
     9841 taattggtcg gctcgtccag cagcaaaata tctggcttct ccagtaacag cttggccagc
     9901 agaatcttgg ttctttgccc tccagataag gaggtcactt ctgtttccat cccaaaatcc
     9961 ataactccta aggcacgcgc aacctcatca atcttagcat ctagggtata aaagtccctg
    10021 ctttcaagac ggtcctgtag ctctccgacc tcctccatta aggcgtcgac atcagctgtc
    10081 tcctctgcca tagacatgta aatggcattg atacgctcct ctgttttgaa tagctcatca
    10141 aaggctgtcc taagaacatc acgcacagtt tgaccaggtt ctaaaacggt atgctgatcc
    10201 aaatagcctg ctgtaacata ctttgaccat tcaatcttac cagcatcagg ctgcaagtga
    10261 ccagtaacaa tactcataaa ggtggacttg ccttctccat ttgctcctac taatccaata
    10321 tgctcgccct ttaaaagacg aaaggaaaca tcttcaaaaa tggcacgatc accaaatcca
    10381 tgacttaact gcttaacttc taatatgctc atgattactt tcctttattg tcatcaaaaa
    10441 agccgttaaa acggcttaca ctctctcaat tatggcaaaa atgcagcctt ttgtcaatga
    10501 aggctgaaaa agcctacgtc atacgcatga aagattttta gcaagaacag aaggtttttt
    10561 gcattttaat gttcagctat ttcaaatatg tcttattatt ttataaattt tactataggg
    10621 aaagccttga aagtgcctgc tttaatttat actatcattc ggaaagaact gtttcgctcg
    10681 tttgttgtgg aaagccgctc acaacaaaga catagagagt ctatgacaac aagagctaca
    10741 ctttagcaag tcttgaccga catgctttat tgcccagtct aattcattaa aaagcgaaca
    10801 ggtctagctt tcggaatttc agaaaactag gcctgttcat ttgttctatt ttgaggcagc
    10861 cttttgtttc ggcctcgtct gtttcaaggt tttcagatcg aacttaagga caaaaaacac
    10921 tctcctgtat cagctaacct tatcattcat tataaaggaa aatgatttct aatacaagga
    10981 aataccgtta tttcattaaa aataactaaa aatagtttgt caaatcatta gttattaata
    11041 ggcttagata acaaaaatga tgatactgct agcaaggtta gctcaaccaa gcctattact
    11101 cgcttcttgc ttttttactg cctgccttaa ttgcttaaaa acagggtata agagaggcac
    11161 agcaataacg gtcacaaggg cagtaccaag actgccacca attttgccaa gtgctgccca
    11221 caaagcaaca gacaggggta actgggcgcc aaaataagca atcaagctat atttcacaag
    11281 attcatgact aattttgctg ctgctgctaa taagccaatt gctacaataa tcatcggttt
    11341 atcaactgat ttcagaagtt tctcataaat cacatgaagc aggtaacaaa ccactaaggc
    11401 ttcaagcact gttatccaga ccacagccgc atagccatta atcatatcaa acagtcctag
    11461 accaatggct gccaccaaag ctgcccttct agcaccatac aataaaacag ccaccaccac
    11521 taaggcattc cctaggtgaa taaattgggc tccaactgga atacgcagca gctcaaccga
    11581 tataaaaata agagcagcaa ataggctaag ctcgatctga tcagtcaatc gttttgatgt
    11641 catctttttc ctccaataat cctctaaacg cggctcccaa gctgcccaat tctacttcgt
    11701 aggcaattcc aagtgaaagc tctcgattta gcgcaacagt agccgctaat gacttgtcta
    11761 agaagctaat aaccatatcc aacaactcat caatagcaag cctgtgaaaa tacccagcgc
    11821 taacaatagc agagacaaga tcacctgtcc catagaaatg ataagggtac cgttttccaa
    11881 aatgatagct aaccgtctct gttgcctttt gataataagc aaagccgatg tgctgatcat
    11941 caaaggatat accagtaagg acaatctctc taggtcctag tgtagctagc ttagacaata
    12001 gcctctccaa atcctctctg ctataggtct ccccaaaata aggaacatca gctaacaaac
    12061 aagcttccgt cacatttggc aatatcagct gtgcagcttg agcgagcaat ctcattgccg
    12121 ataagtgctg cgaggttaac tgcgcataca tgcttccctt gtcagccata ataggatcta
    12181 gcacaaaggg aagctgttgc tttttgatgt aatcaagaat aatcaaagca tcatcaggac
    12241 ggtacaaata accggaaaaa aagccatcaa aggcaagacc cgcttgagac caagtcgtca
    12301 aaaatggctt tagtccctct gacgtgctct gaatataagg cgtcttagca attgcagtgt
    12361 ggcttgataa caaacaggtt ggaagaatgg cctgttcaat ctggcaagcc gccataatgg
    12421 gaatactagc agacagagca accttgccaa ctccgacaat atcatttgca acaataacac
    12481 gttttaacaa ccaataagct ccttcatttc tttttttact attgtaagaa aatccttgat
    12541 gagatacaat aaggatagat ttcatctgta tggggacact tatgacaagt aaatatcaac
    12601 aaatcattgc agacctagag ttggccatgc aatcaaacca attcaaaaag ggagagaaac
    12661 tcccttctat tagacaatta agtcaacagt atcactgcag caaggataca gtgcaaagag
    12721 cacttttagc cttacaatac aagcgcctca tttatgctat tccaaaaagt ggctattatg
    12781 tgcttggtaa aattgaggaa aagcagcatt cctttgagct aagccttgag gattataatc
    12841 agttggccta tgaggacttt cggctctgtc taaatgaagc cctagacggt aaagattctg
    12901 atttatttaa ctactatcat aaggctgagg gacttgagga gctgcgagag gctttgctgc
    12961 cttatttggc tgataatggg atttacgcta acaaaaatca gctgctaatt acctcgggta
    13021 cacaacaggc cctttacatt ttagctcaaa tgagatttcc caatggccgc catcacattc
    13081 tccttgagac accgacctat caccgaatgg agcagctagc gacttcctta ggcttaccct
    13141 atcaaaccat tgaacgtgat gtcaacggta tcaatcttca tcagcttgaa agcatcttta
    13201 aaaccggaca aatcgctttt ttctatacta tttctcgatt ttcaaaccct cttggcctct
    13261 cctacagcaa aaaagaaaag gaaagcattg ttcggctggc agagcaatac caggtttaca
    13321 tcgtagagga cgattatcta ggggactttg catcgcatag tgagcttccg ctacactact
    13381 acgacactca acaccgggtc atttatctga aatcattttc aatgagcgtc tttcctgccc
    13441 tgcgcattgg agccttgctt ttacctgatg atctcaagga aggctttttg ttacaaaagt
    13501 caatgattga ccttgatacc aacctgatca tgcaaaaggc actagcatta tatttagcaa
    13561 atggtatgtt tcaaaaaaac ctaaagcaaa tgaggcaatt tttcaacaat agagcgcata
    13621 acttactaga ttttctacaa aaacaccttc ctaacctagc ttatcagctc actcctcaag
    13681 cactgattat tcaattagat aaagcattca atcgcaaaaa gcttcttaaa ccacaccaca
    13741 cccaaatcat ctcaacaaga aaagcaaggt atatgcttct aacaatcagt cctgatatgc
    13801 catctaagct gctcgacttg ttttcagtga cacatgaaaa gacccaagaa tagctcattg
    13861 ggtctcagtg tcacaaaaat gtcaatagct atttgatttg ctcgaatcgt aaatgaacac
    13921 taatgctatc gccgtaaccg tttctctcca aatctctttg gagccggtaa gcaatataat
    13981 gctctgcaat agtcatgtag cctgcgtcaa tcagacgatt ttcaacaagt gattgaatca
    14041 tattaatcgt cggacgctcc gcctgcacct cttctagatc aataacaacc tttttagtta
    14101 cctgagctag atgctgtctc cagctgtcat caatcacata aactgttctt gctgccttga
    14161 tcaaagcctg ataaatctta tccggatcaa agtctgccag ctgaccgtca cgcttaataa
    14221 tttgcataag agcgcctctt ttcatttagt ttcattgctt acattcatta tgcaaatgtt
    14281 ttcatcattt gtcaagctat taggctccta tgcctcttag ggattatcag tcaaaagaaa
    14341 cactaggatc aaataaattg tcctgtgctg gtcggacaag cccacgctcg tgcaaggtct
    14401 ctgcaatctg aacagaattc caggctgcgc ccttgagcag attgtcagat accacccaca
    14461 tgtgaatgcc cttttcaaca tctaaatcct tacgaagcct tcctacaaag gtctcacgac
    14521 tgccaacagc attaacggcc tgtgggtatc gttgcactcc ggtatcgtcc tctaaaacag
    14581 cacccggaaa ttgtgcaatc gcctccttaa cagcttcgat agtagctact gccttggttt
    14641 caatgtagat agattctgaa tgggctgata aaacgggtat acgaacacag gtcgcagaca
    14701 ccttaatcgt atcgtcctcc atgatttttt tcgtttcatt tgtcattttc atctcttcat
    14761 aggtgtagtc attttcagtg aaacgatcaa tctgtggtaa agcattaaaa gcaattggat
    14821 aatgtctctt gtcaccagct gacggtaaaa cacttgcctc cacctcctta ggagacaagc
    14881 cctggttaat aacctggtca tactgagcta gggtctcacg aatcgctgat tgaccagcac
    14941 ctgaaacagc ctgataggtg gaaacaataa tacgctcaag accccacctt tgacgaatag
    15001 gctccagcgc tatcatcatt tgaatcgtag agcaattagg gcaagcaaca aggccttgat
    15061 gtgtatcaag agcgtgagca tttacctcag gaacaacaag tggaacagct gggtgctgac
    15121 gaaaataaga ggtattgtca accacaacag cacctgccgc aacagcataa ggggcatatt
    15181 ttgcagaaac attgcctcct gctgaaaaaa gggctagatc aatgccttgg aaggctgctt
    15241 ttgttagctc ctcaacaaca aaatcctctc ccttaaatga gaggattttt cctgctgaac
    15301 gtgcagacgc taataattta atagctgaaa taggcagact tgactcctcc agcatcttaa
    15361 tcatttgctg accgacagcg cctgtcgctc caaccactgc tactgtatac cccatagatc
    15421 gacctcactt taactgatga tattgcaaaa aatgatattg gacctattat agcctatttc
    15481 atcacaaaag aaaagcaagc tagaagccag aacaaacgca tgaagaaaat catttattga
    15541 aaaagttgtg aaaatagcaa aatatccatt ttagagtatt ttgacagagt gtttcctgaa
    15601 tttttatatt tttcctctat aaacttttct tgaaaaa
//
LOCUS       DARYVE010000051        14963 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYVE010000051 DARYVE010000000
VERSION     DARYVE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14963
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            6..596
                     /locus_tag="TVW25_001496"
     CDS             6..596
                     /locus_tag="TVW25_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1379114.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TVW25_001497"
     CDS             606..2168
                     /locus_tag="TVW25_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379115.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHHID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TVW25_001498"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TVW25_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1379116.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TVW25_001499"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TVW25_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1379117.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TVW25_001500"
     CDS             4388..5317
                     /locus_tag="TVW25_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379118.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TVW25_001501"
     CDS             complement(5707..6348)
                     /locus_tag="TVW25_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1379119.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TVW25_001502"
     CDS             6685..9156
                     /locus_tag="TVW25_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1379120.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..10496)
                     /locus_tag="TVW25_001503"
     CDS             complement(9330..10496)
                     /locus_tag="TVW25_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1379121.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
     gene            complement(10672..10938)
                     /locus_tag="TVW25_001504"
     CDS             complement(10672..10938)
                     /locus_tag="TVW25_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379122.1"
                     /translation="MSQEIYSKSEIDLKFENLETKIDSKFDLLMQKMDDGFEKQRLNT
                     EKMLSDFKLNLVTDQQKNKKEFMYWAIGIIIALAGIAFPIWFGK"
     gene            complement(11040..11465)
                     /locus_tag="TVW25_001505"
     CDS             complement(11040..11465)
                     /locus_tag="TVW25_001505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379123.1"
                     /translation="METEKINNVNILRSNNSRLSGYATSASYPLILPIIVEFELYNIK
                     QSKTYLFQITATKINDRRQNNHIKDLLSLSSNQTTVTISAERHNTFFPYEGYGTVATK
                     LDFSFNIDSPGDYCIALTLLDSEGSLLDKHSNYYIFGEE"
     gene            complement(11531..11857)
                     /locus_tag="TVW25_001506"
     CDS             complement(11531..11857)
                     /locus_tag="TVW25_001506"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379124.1"
                     /translation="MYFDEFKEYVENNSRAHDYFFERALDYQNAKNARRTPAHRRWKE
                     QKVLKEVETMWTNVVKQLYDNIKLNGKFRKRFMHQEEIDEWVSFMNEHEILESFADSM
                     AEIEFE"
     gene            complement(11870..12157)
                     /locus_tag="TVW25_001507"
     CDS             complement(11870..12157)
                     /locus_tag="TVW25_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1379125.1"
                     /translation="MYKIEFDPKVKKQLKKLDKTASSKIIRWLYANVDGTSLPRLHGK
                     ALTGDLAGLWRYRIGDYRVICDIQDDKLVILAVHIAHRKQVYKLKLPNNKR"
     gene            complement(12157..12387)
                     /locus_tag="TVW25_001508"
     CDS             complement(12157..12387)
                     /locus_tag="TVW25_001508"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379126.1"
                     /translation="MTTFTLTIDEKNKYIADYFKRNNIDDSQLTFEQLLTVLEDAEDY
                     AAGMAVLMEQKDNPDYKTYTLQEVADELGITL"
     gene            complement(12401..13168)
                     /locus_tag="TVW25_001509"
     CDS             complement(12401..13168)
                     /locus_tag="TVW25_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1379127.1"
                     /translation="MSERNLRQVDILEKSKPFQKQLGVKMGRSTLSQYVSGKSVPAQR
                     QLYLLSKTLNVSEAWLMGYDVAIERIPDEKRRATTEISNQPEIVSIYNQLEQPRQEKV
                     LSFANEQLEEQNKVVSTHEELFSVQGVTYAAAASGFGRGFEADEYDTYTVYTDEEPPR
                     YDYAIGIRGDSMLPKYEQGDMLYIVDRGMSTYNGQLCIVVHNGQTYFKKVYTEEDGLR
                     LVSLNKKYNDIFIDYPPAEDTYIKIYDVVGSFTPVEM"
     gene            13376..13609
                     /locus_tag="TVW25_001510"
     CDS             13376..13609
                     /locus_tag="TVW25_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL1379128.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
     gene            13628..13783
                     /locus_tag="TVW25_001511"
     CDS             13628..13783
                     /locus_tag="TVW25_001511"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379129.1"
                     /translation="MVTKFSEEIKIVRTKSSVYVNSVLDVADKKDPASVVAVAELLKA
                     YKSLTEL"
     gene            complement(13784..13987)
                     /locus_tag="TVW25_001512"
     CDS             complement(13784..13987)
                     /locus_tag="TVW25_001512"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379130.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            14047..14508
                     /locus_tag="TVW25_001513"
     CDS             14047..14508
                     /locus_tag="TVW25_001513"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379131.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGNRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            14650..>14963
                     /locus_tag="TVW25_001514"
     CDS             14650..>14963
                     /locus_tag="TVW25_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HEL1379132.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKEVRKYFIQVEKDFNSP
                     EK"
BASE COUNT         4309 a         2869 c         3127 g         4658 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat catattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatca
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatattcc agtactgatc aactgtcaaa tttttgttat aagcaaaatc attgttttct
    10321 attttttgct caatttcagt aagtgcagct ctggcttcct gtagcgtttt taagttgctt
    10381 tttgtagcct ctttcttttt accttttaag taataacccc tacggacgta gtagcgttta
    10441 cctttctttg tatcgtaggt aaagatattt gggtattttg ttttgttgta tttcattctt
    10501 aaatcctttc gttttttgac ttttggacga ggtcgtttga aaggatattg gcatcaccac
    10561 ctttgtgtga tataatttta ggtacaagaa aacgaccttt ttaatggttg tttcttatac
    10621 ggtttcgcct cacgctcaga gtcgccaaac tttgagagcg tggggctttt tttatttccc
    10681 gaaccaaatc ggaaaagcaa tacctgctaa ggcaataata ataccgatag cccaatacat
    10741 aaattctttt ttatttttct gttgatcagt cactagattt agcttgaaat ctgacaacat
    10801 tttttctgta tttaatcgtt gtttttcaaa accatcatcc attttctgca tcaataaatc
    10861 gaatttgcta tcaattttcg tttcaagatt ttcaaacttc aaatctattt ctgatttgct
    10921 ataaatttct tgtgacataa tagattcctc ctgactcttt tctaagtcta ttataccatt
    10981 atttttggca tcaatgttgg aggtttcggg tttatatagt gtaagatatt cactcataat
    11041 tactcttctc caaaaatgta ataatttgag tgcttatcta ataaagatcc ctcgctatcc
    11101 aaaagtgtaa gcgcaatgca atagtcaccc ggactgtcta tgttaaacga gaaatcaagt
    11161 tttgttgcca ctgttccgta tccttcatac ggaaaaaatg tattatgtct ctctgcggag
    11221 atggtgacag tagtctgatt gctggatagt gatagtaagt ctttgatatg attattttgt
    11281 cttctatcgt ttattttagt tgctgttatt tgaaatagat aggttttgct ttgcttaata
    11341 ttatacaatt caaactcaac tataatgggc aatataaggg gataactcgc acttgttgcg
    11401 tatcccgaaa gtcttgagtt attacttcgt aaaatattta cattatttat tttttcagtt
    11461 tccatgctta tctccttaac taattaaaaa ctctaattct tctttgatca acgctccgtt
    11521 agcgacgttc ctactcaaac tctatttcag ccatgctatc tgcgaatgat tccaaaattt
    11581 catgttcgtt catgaaggaa acccactcat caatttcttc ttggtgcatg aaccgtttcc
    11641 tgaacttccc gtttaacttg atgttgtcat aaagttgctt gacaacattg gtccacatag
    11701 tctcaacttc tttgagtacc ttttgctctt tccatcgcct atgagcgggt gttcgcctag
    11761 catttttagc attttgataa tcaagtgccc tttcaaagaa ataatcatga gcacggctat
    11821 tgttttctac atactcttta aattcgtcaa aatacattac tttaaacctc tatcgtttat
    11881 tgtttggcaa tttgagtttg taaacttgct ttctatgggc tatgtgaaca gctaggataa
    11941 caagtttatc atcttgtata tcacagatga ccctataatc tcctatacgg tagcgccata
    12001 atccagctag gtcaccagtt aacgcttttc cgtgcagtct aggtagagaa gtaccgtcca
    12061 cattagcata aagccaacgg ataatttttg aagatgccgt tttatctaat ttttttagct
    12121 gctttttgac tttagggtcg aattctattt tgtacatcat agagtaatac ccaattcgtc
    12181 agctacttct tgaagtgtgt aggttttata gtcgggattg tctttttgtt ccatcaacac
    12241 tgccatacct gccgcatagt cttctgcatc ttctaggaca gtaaggagct gctcgaacgt
    12301 gagctgacta tcatcaatat tatttctctt gaagtagtca gctatgtatt tatttttttc
    12361 atcaatcgta agtgtaaatg ttgtcacaat atctcctcct ttacatttct acgggtgtaa
    12421 aactgccgac aacgtcatag attttgatat aagtatcttc tgctggtggg tagtcaataa
    12481 aaatatcgtt atatttcttg ttgagagata ctaatctaag tccgtcttct tctgtatata
    12541 ctttcttaaa ataggtttgt ccgttgtgaa caacgataca cagttgaccg ttatatgttg
    12601 acatacctct atctacaata tagagcatat ccccttgctc atattttggt agcatgctgt
    12661 ctcctcgaat tccaatagcg tagtcgtagc gaggaggttc ttcgtcagtg tagacagtat
    12721 atgtgtcata ttcatctgct tcaaatccac gaccaaagcc acttgcggct gccgcgtaag
    12781 ttacgccttg aaccgaaaat aattcttcat gcgtagaaac aactttattt tgttcttcca
    12841 attgttcgtt agcgaagctg aggacttttt cttgtctagg ttgttctagt tggttgtaga
    12901 tggacactat ttcaggttga ttagatattt ctgtcgtagc tctacgtttt tcatcaggta
    12961 tgcgctctat ggctacatca tatcccatca gccatgcctc gcttacgtta agggttttag
    13021 ataaaagata gagttgtcgt tgagctggaa cagatttgcc actaacgtat tgcgaaagag
    13081 tacttctgcc catctttacc cccaattgtt tctgaaaagg ttttgatttt tctaaaatat
    13141 caacctgcct taaatttctt tctgacatca gttgttttaa tctatttgaa gtagaactac
    13201 attgcataaa agtagattcc tttcgatgtt tataggttaa ttataaaaca tcttgaacaa
    13261 aagttcaata aaaaaattca aaaaaatgaa ctttgtgtat tgacaaagtt caaaacaaag
    13321 tgtaacataa aagcataaag ttcatgaaca tgaacaaaaa agaaaggagg ttcctatggt
    13381 ttttgattat tcaaaactca gcggaaggat cgttgagaag ttcggcacac agtacaactt
    13441 tgccttggct ttagggctat ctgagcgctc gctatcttta aaacttaata ataaagtaga
    13501 ctggagaagc aaagaaattg cgcaagcttg tcaagagtta gatatcaacg aaaacgatgt
    13561 aggagaatat ttttttaagc aaaatgttca tattcatgaa caaaactaag gaaaggagaa
    13621 aatcaatatg gtgacaaaat tttcagaaga aataaaaata gtaaggacga agtcttctgt
    13681 ttatgtaaac agcgtcttag acgttgcaga taaaaaagac cccgcgtctg ttgtagcagt
    13741 cgcagagctt ttaaaggcgt ataagtcgtt aacagaattg taatcaacta tggtgactta
    13801 tatacgtgac ttgatcgaga ttgaccaaaa cgatgtattg agcgtctgat agtttcagtt
    13861 caataatatt tggattatca gggcactcat ttgcaacttg gcagaatgtg tgttgcttac
    13921 catttgtgaa catgattgta atggtatcag tttcattcgc tagttgttcg ataatatatc
    13981 gtttcataca atcacctcct ttctgctcat attatagcag ttaaggacaa ctagagaaag
    14041 gacactatgc aagcaaatcg aattttttac ggaaaagaaa aaccaacaaa cgcagtagcg
    14101 ggcgattgct ggtttagaga taacgaatta atgatactca aggacaattg ggaagctagc
    14161 gtaaacaact taaagagccc taaagttatc ggagagatag aaatagacct agagcagcat
    14221 gatgtactgc tgacagccag agggaaccgt cctccactat taatgattga tgggataatg
    14281 ttgggcggag tatctaaggt aataattata aatgagttat ccgagtcttg cgcaattgtc
    14341 tctcttaatg agtatatcaa ggagaatttg ttcccttttg acgattttga atcacttcaa
    14401 aggttatttc aaaagggcca tcagaaatta tccgtacggg aactttgctt agaaaaacgt
    14461 ttaggtgagc attcttatca agaccatcga aaaagctgcg atgaatagta aaagttttct
    14521 taccgctcgc aagagctttc tcgtaatcct gagtcagtag tttaacagag agatctaatt
    14581 gatagtcgta cacttttgtt tatcctcctt ccactaggat aactacatta tacaacagaa
    14641 aggaacaaca tgaatcaact aataaacatc accctaaacg aaaatcaaga accagttgtc
    14701 agtggtcgtg atttacataa agtacttgaa atcaaaacag cttataaaga ttggtttcca
    14761 agaatggctg aatatggttt tgaagaaggt caggacttta gctcattttt gagcaaaagt
    14821 acaggaggtc gtcctagtca agaccacgtt ctaaaactag acatggcaaa agagattgct
    14881 atgttacagc gtaacgagaa atctaaagaa gtccgtaaat acttcatcca ggtcgagaaa
    14941 gacttcaaca gcccagagaa aat
//
LOCUS       DARYVE010000052        13551 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYVE010000052 DARYVE010000000
VERSION     DARYVE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13551
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(81..1361)
                     /locus_tag="TVW25_001515"
     CDS             complement(81..1361)
                     /locus_tag="TVW25_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1379133.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVW25_001516"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVW25_001516"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1379134.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTRIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TVW25_001517"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TVW25_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1379135.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TVW25_001518"
     CDS             6342..6845
                     /locus_tag="TVW25_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1379136.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TVW25_001519"
     CDS             7344..8537
                     /locus_tag="TVW25_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1379137.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TVW25_001520"
     CDS             complement(8736..9200)
                     /locus_tag="TVW25_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379138.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TVW25_001521"
     CDS             9468..10316
                     /locus_tag="TVW25_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1379139.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TVW25_001522"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TVW25_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1379140.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TVW25_001523"
     CDS             11592..12071
                     /locus_tag="TVW25_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1379141.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..12433
                     /locus_tag="TVW25_001524"
     CDS             12068..12433
                     /locus_tag="TVW25_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEL1379142.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GALGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLLCLTIVGIPFARQ
                     SLKLAKISLFPFGAIIYDI"
     gene            12452..13096
                     /locus_tag="TVW25_001525"
     CDS             12452..13096
                     /locus_tag="TVW25_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1379143.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
BASE COUNT         4065 a         2973 c         2620 g         3893 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcag cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat tcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcgctttggg tctttttcct tttggaaaag ccatcgaaat
    12241 tggccaagga gcaggcagcc tgctgctcaa tatcatctgg attgtctgct gtggctggag
    12301 cttagcgatc atgcatttga cttctgccct tctcttgtgc ctcacgattg ttggcattcc
    12361 atttgcccgg caatctctaa aattggccaa gattagcctc tttccttttg gagccatcat
    12421 ttatgacatt taattaggaa gcaaaagact tatgaaattg tattttgtca gacatggtaa
    12481 aaccttgtgg aacctagagg gccgttttca gggagctaac ggagattcgc ccttgcttga
    12541 aagctctaag gacgatttgc gccagctagc aagagagctg tgggacattt cttttgatgc
    12601 gatctactcc agcgacctaa aaagagctgt tgatactgct cgcattattg tggacgaagc
    12661 taactgcaag actgatatta gttataccaa gcagctgaga gaatggaacc taggcaccct
    12721 ggaaggaacc aaaatagcaa ctgtatccgc catctacccc agtcagatgt cagcctttta
    12781 tcacaattta gccaaattca agcccagtca atttaaggct gaatcccttt atgaaagcac
    12841 acaaaggctt tatcagctca ttaaaagttt ggaagataag gcctatcagc aggttttaat
    12901 ggtaggacat ggcgcccatt tgacagcttc tattcgtgct cttttaggct ttgagccagg
    12961 tatgcttcgg gcacagggag gactggataa tgccagccta accgttatag aaaccttgga
    13021 tttcaaacac tttcattgtc taaggtggaa tgatacatca tttttacaaa aaaagactac
    13081 tagattaaca ccctagtagc tcttaagcac aaagctccaa gacagctaaa ctgtactcca
    13141 ttggttagag aacacatctc attttttgag ggacgcttta ttagctgtag gaagttatga
    13201 aaagctaaat acacgagagg actaaattgg acaagctcaa aagtttgaca atgtatttca
    13261 aaaaaggatt gaattctgta tcgaacagga ctcagtcctt tttatcattt atcaagccga
    13321 ccaaggcttt caaccacgac aaacgcgcaa aacagttatt tcctgatgat agtagagact
    13381 acagcagata ttttcaatga ttttcttgta gtaacatcta tacaaaacaa tacagctcat
    13441 tgaaatatag gaacattaaa attcagaaag atttcttttc ttgctaaaaa tctttcatcc
    13501 atttcaaact ggttttcatt tgtcctctcc tttttcagtt ctgctttttc t
//
LOCUS       DARYVE010000053        13258 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYVE010000053 DARYVE010000000
VERSION     DARYVE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13258
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(241..489)
                     /locus_tag="TVW25_001526"
     CDS             complement(241..489)
                     /locus_tag="TVW25_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1379144.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(543..1463)
                     /locus_tag="TVW25_001527"
     CDS             complement(543..1463)
                     /locus_tag="TVW25_001527"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1379145.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            1697..2326
                     /locus_tag="TVW25_001528"
     CDS             1697..2326
                     /locus_tag="TVW25_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1379146.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            2425..3702
                     /locus_tag="TVW25_001529"
     CDS             2425..3702
                     /locus_tag="TVW25_001529"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1379147.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            3716..4378
                     /gene="deoC"
                     /locus_tag="TVW25_001530"
     CDS             3716..4378
                     /gene="deoC"
                     /locus_tag="TVW25_001530"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1379148.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            4365..4754
                     /locus_tag="TVW25_001531"
     CDS             4365..4754
                     /locus_tag="TVW25_001531"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1379149.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            4845..5897
                     /locus_tag="TVW25_001532"
     CDS             4845..5897
                     /locus_tag="TVW25_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1379150.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6024..7556
                     /locus_tag="TVW25_001533"
     CDS             6024..7556
                     /locus_tag="TVW25_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379151.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            7549..8613
                     /locus_tag="TVW25_001534"
     CDS             7549..8613
                     /locus_tag="TVW25_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379152.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            8615..9571
                     /locus_tag="TVW25_001535"
     CDS             8615..9571
                     /locus_tag="TVW25_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379153.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(9609..10865)
                     /locus_tag="TVW25_001536"
     CDS             complement(9609..10865)
                     /locus_tag="TVW25_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL1379154.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(11385..13100)
                     /locus_tag="TVW25_001537"
     CDS             complement(11385..13100)
                     /locus_tag="TVW25_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1379155.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         3790 a         2346 c         3065 g         4057 t
ORIGIN      
        1 gcgatcaaga cgcagaacag gggctatagc agcctgatgt gagacaggaa ggacttactg
       61 tcctaccagc tacagtcact acactgctag agcttgcggt gtgagcagca gtaagaggca
      121 aaggcgttac cccagaggga ttgatggatc accatcacta gtttggagcc attagctgtg
      181 ccaaaggttt tctaaagcca aaaagaaaaa actccgattg gagttttcat tggttatgta
      241 ttagctaagc tttgcagcaa gacgtgcttt atcgcggctt gctttatttt tatgaatcaa
      301 accttttgat tgggctttat caatgcttga agaagcagcg cggaaaagct cttcagatgg
      361 gttagcttca aatgccttga tagcagtacg catagctgat ttttgtgctg aatttttttc
      421 gtttgcttta acgttaagct cagcgcgttt aatagctgat ttaatatttg ccaatgtttt
      481 cacctccaaa ttaatctaac tacaccatta tatagaaaat ataggtgttt ggcaagcact
      541 tatcactttt tgagataaat ttcatcaatt ttatggtctg cagctttatg aagaatgagc
      601 tcagctcgat tgcgtgtagg ctcaataaac ttttccagat tttctaggtt aattgttttc
      661 cagacttttt ttgcaaaggc aatggcttca ttttgtggca atgaggtata tctagtgtaa
      721 tagttagccg gatcatgctt agccagctct aaaaggctta agaaccgttc caaataccat
      781 tgctcaatat gatggctatc tgcgtcaata taaattgaaa aatcaaaata atcactcata
      841 tacaatcgat tattctgttg attttgaaaa acattaatcc cttcgatgat gaggaagtca
      901 ggattggtaa aggtttgctg ctgatcagga acgatatcat aaatctcatg cgagtaaaca
      961 ggggctgatg cggtttgtcc tcccttgaca gtatccagaa agtttaacaa tagctccata
     1021 ttataggatt ctgggaagcc ctttcgattc agcatattgt ttttgatcag tgtgctatta
     1081 gggtacaaaa aaccatctgt tgtgaccaac tcaacagtgc tggtcttgtg tgtgcgcgcc
     1141 aaaagaagct gcaataacct gctagttgtg gacttaccga cggcaactga gccagaaatc
     1201 ccaataataa agggtctttg ctgaatatct ttttttagaa agaggctttt agaaaaagac
     1261 aggttttctt gagcgatttt atagacttga atgagatgaa tcaagggaag gtaaacctca
     1321 acaacgtcgt tgatatcaat attatcattc aaactggtga tgctagtaag ctcctcttga
     1381 gtcaataagg gcttgctttt ttgatgtaat tgcttccagg attttctgga aattttttca
     1441 aaagtaataa attcgtttga catagttact cctactaatt ggcagtgctt acattataac
     1501 atgtcaataa aaaaattgaa aaatgtttcg tctgaaattc ttaaaaaaac actgaaaaac
     1561 cctataaaaa tcgaacaatt ttagcctaac aattggctaa tataaagtta atcggtcaat
     1621 gttcggaata tatggttcga taaacgaaaa accaagaaaa acaaacgtct tgtaaaccat
     1681 ttcaaagtgt gatagaatga aaaagcatcg aaaaaagata ggaaaacaca tgacaaaaat
     1741 gtattatgat gaaaatccag atagtgctca tgatatccat caattgacgg tcaatttgtt
     1801 aggacagtcc tttacttttt tgacagattc tggtgttttc tcaaaaagaa tggttgattt
     1861 tggaagtcag gtcctgctca acacattaga ttttcaagaa ggtgatcgtc tgcttgactt
     1921 gggctgcggc tatgggccgc taggacttag cttggcaaag gctcaaggtg ttgaggcgac
     1981 tctagtagat attaatcatc gcgctgttgg cttagctaag cagaatgctg agagtaatca
     2041 ggttgaggcg accatttttc aatcaaacct ctatgacggt gtgacaggga catttgagca
     2101 catcattagt aacccaccta ttagggcagg gaaaaaagtg gttcatgaga ttattgaaaa
     2161 gagtattgat tttttaacta aaggcggtga tttgacagtc gttatccaaa agaagcaggg
     2221 agcaccaagt gctaaagaca aaatggaggc cgtttttggg aatgtgacta ttctcaaaag
     2281 agaaaagggt tactacattt taagaagtat taaggaaagg aattgagctc aagtgtaaaa
     2341 agtggtatta aaaagcatag cggtatttta gtaagagttg ccttctaata tcactatttt
     2401 ctcagagctt ttggtatctt gttgatgaga gcagttgatt taatccaaaa aaagcgtgat
     2461 ggtaaagagc tatctaccga agagatccag tggctgatta atggttatgc caatggtact
     2521 gtgccagatt atcaaatgtc ggcttttgca atggcgatct atttcaaggg aatgtctaca
     2581 cgagaaactc gcgatttgac catgagtatg gttgagacag gtgagcagat tgatttgtca
     2641 gctatagctg gtatcaagac ggacaagcac tcaacaggtg gtgttggtga taaggtgaca
     2701 ctcatcttag ctcctctagt tgctagcttt ggcgttcctg tagcgaaaat gagtggacgc
     2761 ggcttaggcc acaccggtgg aacgcttgat aagctagaat ctatcaaggg ctttcagatt
     2821 ggtcggaccc aagaggaatt tatcaagcag gtacaagaga tcggactttc agttattgga
     2881 caatcagata agcttgtgaa ggcagataag ctgctttatg ctcttcgtga tgtgacggca
     2941 accgttgata ttgttccttt gattgcaagc tctgttatga gtaagaaaat tgctgctggc
     3001 gctgatagta ttttgctaga tgttaccgtt ggtgacggtg cctttatgaa gactattgaa
     3061 gatgctgaga agctgtctag actgatggtt gaccttggta aggaggttgg gcgtcagaca
     3121 gtggctgtca ttacagatat gagtcagcct cttggtcgtg ctatcggtaa tcgcttagag
     3181 gtgctagagg caattgatat catgaaaggc aagggacgca aggatattac tcactttatt
     3241 tgtgagctag ctcagattat gctggagctt gctggtgctc aacactctct tgaggatatt
     3301 caccatcatt tggttggcgg agcagcctta aaaaaattag aagagatggt tgtttatcaa
     3361 ggaggtgatc ttgaggacct ttatcgtcca tcacaggcgg ctgttcaaac agaggttttt
     3421 gcgtcagaag atggttacat cacagcattg cctgctcttg agtttggatt gtttgcaatg
     3481 aggctgggtg ctggtagagc agtcaaaaca gatagtctgg attatgaaac agggattgtc
     3541 tttgacaaga aggttggtga cgctgtcgct aagggagagc gcattgcagt tgtcttttca
     3601 caggaagccc tagacgaaaa aatgcttaca gaatttgaaa aaaatgttaa aataggggcg
     3661 gaacacctag aggctaacga aattatcaaa atcatttcct aaggaggagt ataacatgaa
     3721 tattaacaag tatattgacc acacactact aaaagctgac agcgttcaat cgcagcttga
     3781 ccaattaatt gaggaggcta aagcctatga ctttgctagc gtttgcgtca acccttgctg
     3841 ggtagcctat gctgcaaagg ctttaaaggg aacagatgtt aaggtttgta cagttgttgg
     3901 ttttccttta ggtgcaacta cctcagcaac aaaggccttt gaaacaaagg acgctattga
     3961 aaatggtgct gatgagattg atatggttat caatattggt ctgttaaagc agggtgacta
     4021 ccaagctgtt gaagatgata tgcgtgcagt ggtagaggct agcggagaca aattagtcaa
     4081 ggtgattatc gaggcttgcc tcttgactga tgatgaaaag gttaaggctt gtcagttggc
     4141 ggtaaatgca ggtgttgact ttgtgaagac ctctactggt ttttcaactg gcggtgcaac
     4201 cgtttctgat gtcaagctaa tgcgtcaaac agttggtcca gacattggcg taaaggcagc
     4261 tggtggtgct cgttctctag aggacgcttt agcttttgtc gaagcaggag ctacacgtat
     4321 tggaacttct gcaggggtaa ctattatgaa aggtgaagtt gccaatggag gctactgatt
     4381 tagtttcgtt agccattgaa gctagtaaaa gggcttatgt gccttactca catttcccga
     4441 tcggagctgc tttaaagaca aaggacggaa caatctatac tggcaataat atcgagaatg
     4501 ccagctttgg cttgaccaat tgtggggagc gaacagctat ttttaaggct gtttctgagg
     4561 gacatcagca gcttttagaa attgccattt atggagagac tgatgagcca atctctcctt
     4621 gtggagcctg tcgtcaggtc atggcagaat tttttgaagc cactgctcca gtaacgctaa
     4681 ttgctaagga cggtcgtacc atgcgcacaa ctgttggcga gttacttcct tattcgttta
     4741 cagatttatc gtaatctggc ttaattttgt tatctagcca ttaggcttta tatttacttt
     4801 cggcaattgg tttgctagaa atatttttag gagggttcat attcatgaac aagaaattta
     4861 ttggtgttgg tttagcttct gtagctttat taggtttagt tggttgtggt aatcgtaacg
     4921 cttcaaaggg atctggtgat gctaaaacag atttgaaggt agcagtggtt actgacactg
     4981 gtggtgttga tgataagtca tttaaccaat cagcttggga aggcttgcag gcttggggta
     5041 aggacaatgg actaacaaag ggttcaggct ttgattactt ccaatctaca aacgagtctg
     5101 aatatgcaac taacattgat acagcagttt ctagtggtta tgaggttgtt tatggtatcg
     5161 gatttgcctt gaaggatgca atcagtaagg ctgctgatga caacaacaaa gtacaatttg
     5221 ttatcattga tgatgttatc gaaggcaaag acaatgttgc tagcgtaaca tttgctgata
     5281 acgaagctgc ttaccttgca ggtattgcgg cagctatgac tacaaaaaca aaaacagttg
     5341 gttttgtagg tggtatggaa ggaacagttg ttacacgctt tgaaaaaggc tttgaggcag
     5401 gcgttaagtc tgttgatgac tcaatcaaga tcaaggtgga ctacgctgga tcatttggag
     5461 atgccgctaa gggtaagaca attgcagcag cgcaatacgc agcaggtgct gatgttatct
     5521 atcaggtagc tggtggaaca ggtgcgggtg tcttcaacga agcaagaaca attaacgaaa
     5581 aacgtgacga agctgataag gtttgggtaa ttggtgttga ccgcgaccaa aacgaagaag
     5641 gtaaatatac atctaaggat ggcaaatcat ctaactttgt acttgcatct actataaaag
     5701 gtgttggtaa ggctgttcaa ttgatcaata agcaggcagc agataagaaa ttccctgcag
     5761 gtaaaacaac tgtttatggt ctgaaggacg gtggtgttga gattgccaca acaaatcttt
     5821 ctaaagacgt tatcaaagcc atcgaagaag cgaaagaaaa aattaaatct ggtgacgtaa
     5881 aagttcctga aaagtagtta ctggaaaaga gcgaccttcg tcggtcgccc tttttagagt
     5941 ggaacacctt ttgcttcagt aaaggttgtg acaaatggct ggctttactg aaacaaaaga
     6001 ttaaattgaa aggaaataat cctatggcac agcatgtcat tgaaatgaaa gagattacaa
     6061 aaaaatttgg tgattttgtt gcgaatgacc atattaattt gaatgtcaga aaaggcgaaa
     6121 ttcatgcatt gttaggagag aatggtgcag gtaaatcaac gttaatgaat atgttagctg
     6181 ggcttttaga gccaactagt ggaaacattg tcattaacgg tcagcctgtt gttattgact
     6241 ctccttccaa atctgctaga ttgggtattg gaatggtaca ccagcacttt atgctagtag
     6301 aagcttttac agttgctgag aatatcattt taggaaatga agttgtcaaa aacggttgtc
     6361 ttgatttaaa aaaggccagc aaggacatta aagagctttc tgagaaatat ggtttagctg
     6421 ttgatcctac tgccaagatt gctgatattt ctgtaggggc acagcagcgt gttgaaatct
     6481 taaagacctt atatcgtggt gcagatattc ttatttttga tgagccaaca gctgttttaa
     6541 cgcctgctga aatacaagag ctcatggaaa tcatgcgtaa ccttgttaag gaaggcaaat
     6601 ccattatttt gattactcat aagctggacg aaattagagc agttgctgat agagtcactg
     6661 ttattcgacg tgggaaaagt attcaaacag tagatgtagc aggtgcaacc tctcaggact
     6721 tggctgaaat gatggttggg cgttcagttt cctttacaac agctaaaaag gcagcagagc
     6781 caaaaggggt ggtgctgtcg atcaagaatt tagaggtcga tgaaaatcgt ggaatcccag
     6841 cagtaaaggg gctttctctt gacgttagag ctggtgaaat tgtggggatt gcagggattg
     6901 atggtaatgg tcagtcaggg ctgattcagg ccattacagg cttgagaaag actagatctg
     6961 gtagcattac aatcaaaggt caggaggttg ttcatttaag ctcccgtaaa atcacagagc
     7021 tatcagtggg gcatgtgcct gaggaccgtc atagagatgg cttagtgctg gacctttcct
     7081 tggctgaaaa tactgccctt cagacctatt ataaagagcc actaagtaag aacggtattt
     7141 taaattacaa tacaatcaat gattatgctc gtagactgat gaaggaattt gacgttcgtg
     7201 gtgccaatga attggttcca gctcgtggat tttctggcgg taaccaacaa aaggctatca
     7261 ttgcacgtga ggttgaccgt aaccctgatt tattgattgt cagtcagcca actcgcggct
     7321 tggacgttgg tgctattgag tacattcata agcgtttgat tgaagagcgt gacaaaggca
     7381 aggccatcct cgttgttagc tttgagcttg acgaaatctt gaatttatct gaccgtattg
     7441 cagttattca tgacggtaaa attcaaggca ttgtgttgcc tcaagatacc aataagcaag
     7501 aattgggaat tttgatggct ggtggttcca ttgataagga ggagagtcat gtctaaaaat
     7561 gcacaaaaga ttgctgtgcc aatgatttct atcttgttag gattcttact tggcgctatt
     7621 gtcatgttta tctttggcta tgatccaatt tggggctatg agggcctatt tcaggtagcc
     7681 tttggtagta tcaaaaatat tggtgaaatc ttcagagcga tgggaccact aatcctgatt
     7741 gcacttggtt ttaccgttgc tagccgtgcc ggcttcttta atgtcgggct gtcaggtcaa
     7801 gctttggctg gttggattgc tgcgggctgg tttgctcttg tcaatcctaa tatgcctcgt
     7861 ccgcttttaa ttctgatgac tgtcttgatt ggtatggttg ccggcggaat tgctggcgct
     7921 attccaggta ttttgcgagc ttatcttggt acgagtgaag ttattgttac cattatgatg
     7981 aattatatta ttctgtatgt cggtaacgct atcattcaaa gaggctaccc tgaaagtgtt
     8041 aagcaaagta ttgattcaac catacaggtc agtgataatg ccagctatca aagtcaatgg
     8101 ctgtcagatt taaccaataa ttctcgtatt aatatcggta tcttttttgc gcttattgca
     8161 attgcagtta tttggttctt actaaacaaa acaaccctcg gatttgaaat tcgttcagta
     8221 ggtcttaatc cacatgcttc agaatatgca ggtatgtcct taaagcgtac gattatccta
     8281 tcaatgatca tttcaggtgc tttagcaggc ttgggaggag ttgttgaagg cttgggaacc
     8341 tttgagaatg tttttgtaca gggaagctct ctagcaattg gttttgacgg tatggctgtt
     8401 agcttgcttg ctgccaattc accgattggt atcttcttct catcattcct atttggggtg
     8461 ttgagcatag gtgctcctgg tatgaatatc gcaggaattc caccagaatt ggtaaaagta
     8521 gtgactgcct caattatctt ctttgtaggt gctcactacc ttatcgaacg ctatattatc
     8581 aggcctaaaa aactagtaaa gggaggtaaa taagatgagt ttagttacta tttttgcttt
     8641 attggtttca tcaatgctta tctatgctac acctcttatt tttacaagta ttggtggtac
     8701 cttctcagaa cgagctggtg ttgtcaatgt cggccttgaa ggcattatgg tcatgggggg
     8761 gggttcaggc attgtcttta atcttgaatt tgctcatatc tttggtaaag ctactccctg
     8821 gcttgcagtt ttggtgggag gagttgttgg attgatcttt tcattgatcc atgcgcttgc
     8881 aacgattaac tttagggcag atcacattgt cagtggtaca gtgctaaatc tgctggcacc
     8941 atcgcttgcc attttcttag ttaaggtgat gtacggtaag gggcaaactg ataatatcca
     9001 gcaatcattc ggtaagtttg attttccgat tctctcaaaa attccagttc ttggagatat
     9061 attctttaga aatactagct tagttgggta tttagctgtt gccttttctt tcctagcttg
     9121 gtttgtgctt tacaaaacaa gatttgggtt gcgtttgcgc tctgtaggtg aacaccctca
     9181 agcagctgat acacttggta ttaacgttta cctcatgaaa tattatgggg ttatgatctc
     9241 tggttttctt gggggtattg gtggagctgt ctatgcacaa tccatctctg ttaacttcgc
     9301 agtgacaacc attttaggac ctggatttat tgcccttgcc gctatgattt ttggtaagtg
     9361 gaatccggta ggtgctatgc tatctagctt gttctttgga ttatcacaaa gcttagcagt
     9421 tattggggca caattaccag tattggaaaa aatcccaacg gtttaccttc aaattgcgcc
     9481 atacctattg accatcatca ttttggctgc tttctttgga caagcagtgg ctccaaaggc
     9541 agacggtgtt aattacatca aatcaaaata aaaaaagctc aatgtcaact gtagtgggtg
     9601 actgatagct aagcacgaga gaagacgaat gtcgtcttct cttttgtgat attcaaagcg
     9661 aggtagatac gttttttaaa gttgtcaaag ttccgaaatc cgaaagcatt gcgcttgata
     9721 tctttgataa gtttgttagt ggcttctaac ttagcgttag aataaggcag ttgaatggca
     9781 ttggtgatgt aatcttggta gcgactaaag gtatttagag ctgttttaaa agtctgatta
     9841 agatgtggta gtgtgtcatg aattaaacca aagaaatgct tggcattctt ttcttgcagg
     9901 tgaaaaagga gcagctggta caggtcataa taagagttta actcaggcac tagtgagaag
     9961 atcttattga gacattctct aggagttaag gtttgtctga aggtgcggga atagaaaggc
    10021 ttaagagacc gttttctgct atccttttga ataagcttcc agtagtactt aagagctcta
    10081 tatttaagag acttcttgtc aaatggtttc atgatgtcac tacgtatttg cttgagagct
    10141 ctattgatgt gctggacaat gtgaaaacga tcgagaacga ttttagcctt aggaaataga
    10201 attttaatga gaggaatata acttccagac atatcgacag tgacgacttt caccttgttt
    10261 ctagcctctt tagagtactt aaagaaatga tttcggatgg ttgtttgacg tctattatca
    10321 agaatggtaa tgattttctt agtgttaaaa tcctgagcaa tgaaggctaa tttacctttc
    10381 tgataagaga actcatccca agagagaact tctggcaaat tggcgtaatc ctctcggaaa
    10441 tgatactgct taagcttgcg atagacggta gaagtggaga tagcgagctt agaagcgata
    10501 tgggtgagag cctttctgtt gagtaaaagc tgagcgattt tctgtctcac tatctcagaa
    10561 atttggcaat ttttcttaac cagggtagtt tcagatacag tgacttttcg acaggatttg
    10621 cattgaaacc ttcttttttt caaacgaatg agactaggaa agcctccaat ttcgataaag
    10681 ggaattttag agggcttctg gaagtcgtat ttgatttgtt ttcccgcaca cagtttacat
    10741 ttaggagggt tatagtctag tgtagcgatg acttcaatat gagtatcatg ctggatagct
    10801 ttagtcaagg tgatatgttt gtctttgatt ccaatgagtt gtgtggtatt attgaggtgt
    10861 tccataagat accttctaaa tgatagttta gtcgcttttc atgataagtc ttatgggact
    10921 tttttgatac tcaaaaagcc ctataatctc cacagtagcc ttacccacta cagaaattat
    10981 agagccatct tagaacactg gacttgttcg ctttttaatg aattaaattt agtagatcct
    11041 ttaaaggcat gctatcaagc tttttatcct tgacttttgt ttagcaagtg aagtgttcac
    11101 aaaagctagc taaaacactg agctgacaat gtagagaatg gctcgttttg acaaggttag
    11161 agtgcttttt gctgtatggt ttttaatcca cgcacctgaa aaagaaagga caggacctgt
    11221 gcgagcttac ttgtggttag taggtttcaa ttcatgctcc caaaaaggaa gcaacgcaac
    11281 tctgagaaag gtcttagacc actttcccag tttgcctcac agctaatggt gtaaaacaaa
    11341 tagaccaccc tgtaacaggt ggtcatggtt agatatcagc tcatttaaga gacaaaggcg
    11401 ttgatttcag attcaatatt ggcaattttt tcttcggcaa gcgcaagggt gtcaccaaca
    11461 gttgcgatat aaaatttaat ttttggctct gttcctgatg gtcttacagc aaaccatgaa
    11521 tcatcagcta gggtatattt taagacattg cttggaggag tggttagctg ggtttgacca
    11581 gctttatgag ttgccgtctg actgaggaaa tcctctgtta acacaatatc agtgtgatta
    11641 aactgcgcag gggcatgctt gcggaattta tccataatct gtttgatttc agctgcgcca
    11701 tcaacaccag acagtgtaac agaaatggtt ttttctgcaa agtagccgta ttctttgtaa
    11761 atgtcatcaa taccatcagc aagggttagt ccacgagagc ggtagtaggc agcaatctca
    11821 gccaccaata gcaccgcttg aatagcgtcc ttatcacgta caaatggttt aatgagataa
    11881 ccaaagctct cctcaaagcc aaacatatag gtgtaattgt gcttttcttc aaattcttga
    11941 attttttcag caatgaactt gaagcctgtt aagacattaa acatggttgc cccgtagctc
    12001 tctgcaattt tagtcactaa ttcagtagag acaatggatt tggcaagagc ggcattgtta
    12061 ggtagggttc cagcctgctg atgtgcttct aaaatatact tagcaattaa agcaccaatt
    12121 tggttgcctg ataggttgcg atagctgcca tctgcctgcc gaatttcaac cccaagacgg
    12181 tcagcatctg gatcagtagc aacaagaaca tcagcatcaa cctgacgtcc aagctcctca
    12241 gcaagagtaa atgcctcttg actttcagga ttaggagatt tgacggtaga aaaatctgga
    12301 tctggcttag cctgcacctc aaccacctga acggacttaa agcctgcttg tgccaaggca
    12361 cgacgtgcta gcatttcacc tgttccatga agaggtgtat agacaatttt catgtcacga
    12421 ccatagtcat tgatgaggtc ttggttgata ttgacctttt tgacctcttc taaataagca
    12481 aggtcaacag cttcaccaat aacctcgatg agcccattag ctttggcttt ctctaaatca
    12541 gcaagcctaa tggcaaaggg gttatcaatc gcacgaatgt aatctgttag agcgtcggcg
    12601 tcagctggag gcatttgacc gccgtcagac ccataaacct tatagccgtt gaatggtgca
    12661 gggttgtgac tggcagtaac catgataccg gcaaaagcac ccaaatgtcg cacagcaaag
    12721 gaaagctcag gtgttggccg aaggctttca aaaacgtatg atttaatgcc atgagctgct
    12781 agtacctgtg cagattcaaa ggcaaattct ggagaaaaat gacgagaatc ataggcgata
    12841 gcgacaccgg ccttcttagc agcttctccc tttgactcaa ctaatgctgc caagccctca
    12901 gttgcttggc gaacaacaaa aatattgata cgattcgttc cagcgccaat atagccacgc
    12961 ataccagctg ttccaaattc aagattggtg tagaaggcat cttcctttgt tttttcgtcc
    13021 atgctaagta attcatctct taaataggct ggtagatctg gaatatcaag ccatttttga
    13081 tagttttctg tgtaagtcat agtattctcc tttatatttt taaccgcttt cattatatca
    13141 tgttgaaaag gaaaaatcac ttattttctg taatagcttc caatcatttt ttcacataag
    13201 gatcaatttc cttgcttccc gactttatca cttgttttag tccacacctt actcaacc
//
LOCUS       DARYVE010000054        13162 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYVE010000054 DARYVE010000000
VERSION     DARYVE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13162
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            124..684
                     /gene="ahpC"
                     /locus_tag="TVW25_001538"
     CDS             124..684
                     /gene="ahpC"
                     /locus_tag="TVW25_001538"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1379156.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            705..2237
                     /gene="ahpF"
                     /locus_tag="TVW25_001539"
     CDS             705..2237
                     /gene="ahpF"
                     /locus_tag="TVW25_001539"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1379157.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            2698..3468
                     /gene="rpsB"
                     /locus_tag="TVW25_001540"
     CDS             2698..3468
                     /gene="rpsB"
                     /locus_tag="TVW25_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1379158.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            3636..4676
                     /locus_tag="TVW25_001541"
     CDS             3636..4676
                     /locus_tag="TVW25_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1379159.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(4876..6771)
                     /locus_tag="TVW25_001542"
     CDS             complement(4876..6771)
                     /locus_tag="TVW25_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1379160.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(7323..8255)
                     /locus_tag="TVW25_001543"
     CDS             complement(7323..8255)
                     /locus_tag="TVW25_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1379161.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(8252..9109)
                     /locus_tag="TVW25_001544"
     CDS             complement(8252..9109)
                     /locus_tag="TVW25_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1379162.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(9112..10455)
                     /locus_tag="TVW25_001545"
     CDS             complement(9112..10455)
                     /locus_tag="TVW25_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1379163.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(10468..10755)
                     /locus_tag="TVW25_001546"
     CDS             complement(10468..10755)
                     /locus_tag="TVW25_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1379164.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(10757..12799)
                     /locus_tag="TVW25_001547"
     CDS             complement(10757..12799)
                     /locus_tag="TVW25_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1379165.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
BASE COUNT         4030 a         3023 c         2612 g         3497 t
ORIGIN      
        1 ttcacatatg aaattgttag aaaagaacat caaaaacctt gataaatcta gggtttacaa
       61 gtggacagat aagatttctt agcttataat acaggtatca aatgtaaaaa aggaggacat
      121 gacatgtctt tagtaggaaa ggaaattgct gaattttcag cccaagcttt tcacaatgga
      181 aaatttatca ctgtaactaa tgaggatctt aaagggaaat gggcagttgt ttgcttctac
      241 ccagcagact tttcttttgt ttgcccaaca gagctaggtg accttcaaga gcaatatgaa
      301 atactaaaat ctttaggtgt tgaggtttat tctgtatcta ctgatacaca ctttgttcat
      361 aaggcatggc acgatgattc agatgttgtc ggaacaatca cttacccaat gattggtgac
      421 ccatcacatg ctatttcaca agcctttgat gttcttggtg aggatggact tgctcaacgc
      481 ggtactttca ttattgatcc agatggtgtt atccaaatga tggaaatcaa tgctgatggt
      541 atcggacgtg atgcaagcag cttgattgat aagattcgtg ctgctcagta cgttcgtaag
      601 cacccaggtg aagtatgccc agccaaatgg aaagaagggg ctgaaacact aacacctagc
      661 cttgaccttg tcggcaaaat ttaagcaggc aaaggagaaa agctatggca ttaagtcctg
      721 atattaaaga gcagcttgct caatacctta atcttttgga atctgactta gtcctacaag
      781 cttatcttgg tagtgacgat agctcacaaa aggtcaagga cttcattgaa gaaattgctg
      841 ccatgtcaga ccgtatcact gttgaggaga ctaccctaac acgtcaacca agctttaaga
      901 ttacccaaaa aggtcaagac agcggagtga tctttgctgg actgcctcta ggtcacgagt
      961 ttgcctcctt tatccttgct ctattacagg tttcaggacg tgcaccaaag attgagcagg
     1021 atattattga ccgcatcagg gctattgacc gtcctttaag ctttgaaacc tatgtcagct
     1081 taacgtgtca taattgccca gatgtggtcc aagccttgaa cattatggct gttcttaata
     1141 agaacatttc acatactatg gttgagggtg gtatgttcca agaggaagtc aaggcaaagg
     1201 gcatcatgtc tgtgccaact gtctttttga atggagaaga attcacctct ggtcgcgcca
     1261 ctattgagca gctgcttgag caaatcgcag gacctctatc taaggaggcc tttgctgata
     1321 aaggagtcta tgacgtcctt gtcattggtg gaggacctgc aggaaatagt gctgccatct
     1381 atgctgctcg taaaggctta aatacaggtc ttttggctga gacctttggt ggtcaagtca
     1441 tggaaactgt aggtatcgaa aacatgatag gaaccctgta tacagaggga ccaaagctta
     1501 tggcccaggt tgaggagcat actaaatcct atgatgttga catcatcaaa gcccagctgg
     1561 ctacttcgat tgagaaaaaa gaccttgttg aggttactct tgctaatggc gctgtcttga
     1621 aggctaaaac agctattcta gcgcttggtg caaaatggcg cagtatcaat gttcctggcg
     1681 aaaatgagtt taaaaataaa ggagtaacct actgcccaca ctgtgacggt cctctctttg
     1741 aagataaaaa cgttgctgtt atcggtggtg gtaactctgg acttgaggct gcacttgatt
     1801 tagctggctt agctaagcat gtctatgttc ttgagttctt acctgagctt aaggccgaca
     1861 aggtgctaca ggatcgcgct gctaaaacag acaatatgac tattctaaaa aatgttgcta
     1921 caaaggatat tgttggggac gatcatgtca cagggcttaa ctatatcgag cgtgacagca
     1981 atcaagaaaa gcatcttgac cttgaaggag tctttgtaca gattggcttg gtgccaaata
     2041 cagcttggct caaagacagc ggtatcagct taaccgatcg tggcgagatt attgttgata
     2101 aatatggttc aaccaatatt ccaggtatct ttgccgcagg cgactgtaca gattcagcct
     2161 acaaacaaat tattatttct atggggtcag gtgctactgc tgctattgga gcatttgatt
     2221 acctgattcg tcagtaagtt agcaaaaaac caaggtaact gtttaccctg gtttttgctt
     2281 tttagaggcc taataaacag caaggctgat agatcaagca tttggggtac gccaaatgct
     2341 tgaagaaact tatgttctct gatatctttt catgattcat gtgttctttt tcagaaagat
     2401 tgatagtaaa actaagctgc gcttgaaaaa tggatcgtgt caaaacgtca acatatcaaa
     2461 aatgcattga aaacatgcat atggttagaa aataatggca tgcattttcc tcatgcgtac
     2521 gacgtgggtt ttagtgtatt taggcttgct atgactagct ttttttggta tactgttgta
     2581 gttgtgcaga caacaaatac tcatcttaga tcgattgtga ttctgttgcc atcaggtgga
     2641 gttgcaagcc gacgtctaag agaggaaaaa aacatttcta taaaggagaa actactcatg
     2701 gcagtaattt caatgaaaca acttcttgag gctggtgttc actttggtca ccaaactcgt
     2761 cgctggaacc ctaagatggc taaatacatc ttcacagagc gtaacggtat ccacgttatc
     2821 gacttgcaac aaactgtaaa attagctgat caagcttacg agtttgttcg tgatgcagca
     2881 gctaatgacg ctgttatctt gtttgttggt actaaaaagc aagctgctga agcagttgct
     2941 gacgaagcta ctcgtgcagg tcaatacttc atcaaccacc gctggttggg tggaactctt
     3001 acaaactggg gaactatcca aaagcgtatc gctcgtttga aagaaatcaa acgcatggaa
     3061 gaagaaggaa cctttgaggt tcttcctaag aaagaggttg cacttcttaa caagcaacgc
     3121 gcacgtcttg aaaaattctt aggtggtatt gaggatatgc ctcgtatccc agatgtgatg
     3181 tacgttgttg acccacacaa agaacaaatc gctgttaaag aagctaagaa gcttggtatt
     3241 ccagttgtgg caatggttga tacaaatgct gacccagatg acattgatgt gatcattcca
     3301 gctaacgacg acgctatccg cgctgtcaaa ttaatcactg ctaaattggc tgatgctgtt
     3361 atcgaaggcc gtcaaggtga agacgcagag gttgcatttg aagctgatac tcaagcagag
     3421 tcaatcgaag aaatcgttga ggttgttgaa ggttcaaacg aagcttaagt caggcttatt
     3481 gaactaggat agcttcttgc tattcataac atggtctaac ggggcaaagc attccgctct
     3541 atctcgttat tttttaagta agaaaaccca gcaggtcaaa ggctctgcta aagcgagctt
     3601 taagaggacc gattctaatt ttggaggaaa taaaaatggc agaaattaca gctaagcttg
     3661 taaaagaatt gcgtgaaaaa tctggtgccg gcgttatgga cgctaaaaaa gcacttgttg
     3721 aaacagatgg cgacatggaa aaggctattg agcttcttcg tgaaaagggt atggcaaagg
     3781 ccgctaaaaa agctgaccgc gttgctgctg aaggcttgac aggtgtttat gttaatggta
     3841 acgttgctgc tgttgttgag gtcaatgctg aaactgactt cgttgccaaa aacgctcaat
     3901 tcgttgaatt ggtaaacgca actgcaaagg ctatcgcaga aggtaagcca gctaataacg
     3961 acgaagcact tgctcttatc atgccttctg gtgaaacact tgctgatgct tatgtcaatg
     4021 caacagctac aatcggtgaa aaaatctcat tccgtcgctt tgccctagtt gaaaaaactg
     4081 atgaccaaca ctttggcgct taccaacaca atggcggccg tattggcgtt atcactgttg
     4141 ttgaaggcgg agacgaagca cttgccaagc aagtatcaat gcacgtcgca gctatgaagc
     4201 caactgtttt atcatacact gagcttgacc cacaatttat caaggacgag ttggcacaat
     4261 tgaaccacgc tattgagctt gacaatgaat cacgtgcaat ggttaacaag ccagcacttc
     4321 cattcttgaa atatggttca aaggctcaat tatcagctga cgtgattgcg caagctgaag
     4381 aagacatcaa ggctgagctt gctgctgaag gtaagcctga aaagatctgg gacaaaatta
     4441 tcccaggtaa gatggatcgc ttcatgcttg ataacactaa ggttgaccaa gcctatactc
     4501 ttcttgctca ggtttacatc atggacgaca gcaaaacggt tgaagcatac cttgactcag
     4561 tcaatgctaa agcgattagc tttgctcgct ttgaagtcgg tgaaggtatt gagaaaaaag
     4621 ctaacgactt tgaatcagag gttgctgcta caatggcagc tgcgcttaac aactagtcta
     4681 atcataagtc ataagattga ggacagcttt taagagctat cttcaatctt tttttacgcc
     4741 taaaaaaaga gcttttcgag cctatccaac acaaaaagac taagagaagc atgccttcct
     4801 ccacaagcta gactatacgt tctaacgata ggagggccgt acaaagcctc ttagtctttt
     4861 tttaatgagc aatgattacc aaataatcac acgatcctct ggagcacgcc acattggatc
     4921 accttcttta atgttaaatt cttggtggaa ttcatcaaag tttgtcaagg tcacattagt
     4981 acgccattga ccaggtgcgt ggacgtcaat acttgccatc atttgcatga attcctcacg
     5041 cgccttcata cgccagatgg tggcaaagtt gataaagaaa tctctggcag aaaaatctgg
     5101 ctctgactga gctgcctcta aggcacaggc aacaccacct aggtcagcaa cattttcaga
     5161 cactgttaat ttaccattga ctttagcacc ataggagtca aggccatcaa attgctctac
     5221 aattttatcg gtacgctcct tgaaggcggc ataatcctcg tctgtccacc aattctttag
     5281 gctaccatgc tcatcaaagg aagcaccgtt ggtatcaaag gcatgcgaaa tttcatgagc
     5341 aataacagca ccgataccac cataattagc tgatgagctt tgactcaacg aataaaacgg
     5401 cgcctgcaga atagctgctg ggaacacaat ttggttttgc tgtgggtcat aataagcatt
     5461 aaccatgttg gcaggcatgt gccattcact acgatccaca ggcttattcc acttgctcca
     5521 tgaatgagca attgaaattt tggctaaatt ctgagcattt tcaacaagtg atagcttatc
     5581 atcgatgacc tttttagcat aggtttctgg taatttttcc ggatagccaa tgtgtggggt
     5641 gataacattt agctttgtaa tggctttctc acgtgttgct ggtgcaagcc aatccgcagt
     5701 ttcaagacga gatttataaa cctcaatcat cttagctacc ttgtgttcaa catcagcctt
     5761 agcctctggt gaaaattttt caccagcata ccaaagccca agagcttgat taaatggtcc
     5821 ttgtgctaag taataggctg cttttttctt gtccatagcc tgtggagttc ctgacaaggc
     5881 acgactgtaa actcctgata gcacacgaat ctcgtcagtc aaataagcat gataagcacc
     5941 tgctgctgta agcactagcc aggcttttag cagctcccaa ttcttctcag aataatagtc
     6001 agctgcaaat tctgtccaga accgctcctc tggcacaaca accttgtctg gtacttcacc
     6061 taaaatcaca gtaaatatat tatctaaagg caattctggc actagcttgg taaactcggc
     6121 ccagtcataa gggtggtaaa gcttggcata ctctgaatat tcctcacgag aaaggacata
     6181 atctgccagc tgtttatcaa gcgtgataac cttatccagc aagtccttaa cctcttcatg
     6241 tgaaaagcca aatttaggca atagctcctc ttgcatgcca cgccagatag caagcagctc
     6301 tttgcctttg tcattgtctt tggcatagta agtggtatct ggcaggataa gacctggtgc
     6361 ctctgcccaa aggacattta actgagcatt cataaagtct ggtgctacac taaatggaaa
     6421 ctgatttggt tttccattta gctcataatc agccaccttg ctagcaaact cggcaaaaga
     6481 tcctaaggcc ttgtattctt caattaagtc caaggctggc gctacgccca cctgatcacg
     6541 cttgtcataa tctgcaacca agcggtgaaa cttgacaaag ttttctaata tagcgtcatt
     6601 gggaacatgc tcaccagcca accaagcatc tgttgtggtc agcattaagt cctcaatctc
     6661 atctgctagg tctgaaaagc cccctgtacg aggcttatcg tctgggataa cagctgtttc
     6721 tgcccattga ccattgacgg cttgataaaa atcttcttga tatgttgtca tgaattgctc
     6781 cttttttaaa ttaaaccatt atgttaggac tagcttttac tcctcataat gtaatctctt
     6841 acattttacc aaaaaatcgt tcaaaatact cgttttatat taactttctg ttcaaaaata
     6901 agctcattct tcgtatcgca tggcatagat agtaaacgct tagctgcttt ggtcctttta
     6961 tcagtaagat taatcataaa aactgaacaa tcactaagaa atcaaacgat tcttctccag
     7021 cttcatgaaa acagccctca caatatgcca aaaactcagc agtaatagca aaaggcccta
     7081 tcagtcctga caaaagaatt gcaccccaaa ggtgaagata aaacctaaag cttaagaact
     7141 ttttctatga cattaaaatt agaaggtgaa atcaagagtt atcaatcatt atttcacgcc
     7201 tacagagtga aagggactga aagcgcataa ctaaaaggac tgaaccctgt ttcatacaaa
     7261 gctcaatcct aatctataag gtccagcttt ttgggtgtgg tacacctgat aggctttttt
     7321 agctaatctg ccgctaaaat cctcaaaacc tgctgctcaa tagctgctgg cgtcagctgg
     7381 tattcctcta atagataatc catctgtccg acctgaccga aacgttcgtc cacccccata
     7441 cggtaaactg gagtattact ttcctgagcc agtagctcac agatagcact cccaagccca
     7501 ccgatacgat tatgattttc aacggttaga acaggactgc ctgtaagtag accctttagc
     7561 tcatcggcca gtggctttac cctgaaaaca tcaatcacac cgatagagta gccctgctct
     7621 gccattttat cggctacctc taagcacctt ttgaccatga tccctgagca agccagcaca
     7681 aggtcttttc cttgacgcaa taggcaatag ccattagaaa agtcctcatg cccttgataa
     7741 atagcctctg gctttttacg aatggttcga atgtatttta ggccatcgag tgatagggtt
     7801 tcctttaaaa cagctttaaa ttgaacgtca tcactgacct cataaacaat agcccttgga
     7861 atcaggcgca gcagtcccag atcctcaaag ggcatatggg tgccgccatt catttccgca
     7921 ctaactccgg catcagagcc aataaccgtt gcgcctagct gggcataggc taatgaaaga
     7981 aacagctgat caaacacacg acgtgaggca aagggaccaa aggtgtgtag gtaaggctta
     8041 tagcctttaa tcgccaggcc tgctgccaga ccgaccattt ctgcttccat aatgcctaca
     8101 ttaatatagc gcttgccaaa cacctgatcc aaatggttgg tggccattga gcttgataaa
     8161 tctgcctcta agacgactac ctcagggtgc tcttggttgg ctgcaatgag gaaatctcgg
     8221 taaacatgac gcatttcttg acttgctcga gtcatcttgt cacctccaaa ctagctcgta
     8281 gctttctgac agcggcagca agcatctcct tttcggctgc tgttggtctt agatggtggt
     8341 tagctgccat tgactctagc tggctaacac cctgaccctt gacggtatct aagacgatac
     8401 acttgggctt atgacttgat gacgcctgca aagccctgat ggcttcaaaa atagcctgaa
     8461 catccctacc atctacacgt aagctttcaa agccaaatgc cgtaaacttt tcaacaaaat
     8521 cacctggacg acagattgcc tcggttgttc catctaattg cttcttattg tcatcaacaa
     8581 agacaatgaa atgacttagc tgctggtgtg ccgcaagctg gatagcctcc cagcattggc
     8641 cctcgtttaa ttccccatca ccaacgattg cataggtata atgtggtgac tgctcaagcg
     8701 cttgagcata ggcaatgccc gttgctacgc taattccctg accaagagag cctgtcgtca
     8761 tgtcaatacc aggcgttaac agacgatctg ggtgcgaggg cagacttgtt ccattggtat
     8821 taagagactg taaaaaggcc ttatcaaaaa acccctttaa gtagagagtg ctatagaggg
     8881 caggacccgc atgtcccttt gataacacca gataatctct atctgactgg acaaagagct
     8941 ctggtgtcat gggcatgatt tctccataaa gcacagccag caattctaca atagacaagc
     9001 taccgccata atgaccaaag ccaagatgat taagagtctc caaggtattt agacgaatct
     9061 ctgctgcgaa tcgcttcaca tctgttagag gctcatcact caaaaccatg cttattcctc
     9121 cttagctact gattttccaa caacagaaag cccaacaagt ccagctaata tcacaaaaat
     9181 accaatcaca atagctgtca caccacctat gctgttaagt gttcctagta aaatacctga
     9241 taagccaaaa tcggcatctg agaaggttga gccctcaaag cccaagccgc ctaaaacagg
     9301 catcaagaaa atcggaagat agctaataag aacaccctgt aaaaaggctc ccacagttgc
     9361 accgcgcaca cctccagaag cattcccaat aacaccagct gtggcaccac agaagaaatg
     9421 aggcacaacg ccaggtaaaa tcactgtcgt tccacttacg atcatcacag ccatgctcac
     9481 aaggccacca acaaagctag aaacaaagcc aatcagcact gcattggggg cataaggata
     9541 ggcaatcggg caatccaagg ccggcttaga atgtggcact aatttttcag aaatgccctt
     9601 gaaggctgga acaatttcac ccagaatcaa acgaacacca gctaaaatca caaagacgcc
     9661 tgcagcaaac tgtcctgcca actgcaaggc aaagaccaag ccatgtgtgc cagaggataa
     9721 ttccttacta atccaagtag gaccagcaaa aatagctaca atcaaataaa tgattgccat
     9781 tgataaggta atgcttactg tactatcacg caaaaaagca aggctctttg gaaaatcaat
     9841 gtcctctgtt gacttggttt tgtctccaac aagacctcct acaaaaccgc ttaaccaata
     9901 accaagagag ctaaaatgcc ccaaagcgac cttatcgtta ccagtcagct ggatcatata
     9961 ccgttgcaca agagccggtg aaacactcat gataatccct aaggccagcc caccaaacac
    10021 aatcaaggac actgacgtca agcctgcaac agacataatc acagcaatca tacaggccat
    10081 gtaaagtgtg tgatgccctg tcaagaagat atacttaaat cgggtaaagc gagcaatcaa
    10141 aatattaaag atcattcctg taaacataat cagagctgtc gctgacccat aggtcgtcaa
    10201 agcaactgca acaatagcct cattatttgg cacaacacca gacagatgaa aggcatgctc
    10261 aaacatcgtt ccaaaagggt tgagtgagcc ttgcacgata cctgcaccac ctgaaaccac
    10321 taaaaaccca acaaaggtct taatgcctcc cttaacaatg tcaggagcag gctttttttg
    10381 aagtaagaga ccaacaatag caatcaaggc aaccaaaata gctggtgtgc taacaatatc
    10441 aagtaaaaat gtcatcttat cctccttcta aacaagcccc ttttcctggc aaatagcctt
    10501 taccagacta gtcaattcgt ccatatcaat gatactattt aaaatcctca catctcccag
    10561 atgctctgcc gagtctgcca aatcacgccc aacaatccac acatctgccg ctgtgggatc
    10621 cgcgccacca agatcataat gctccacctc aacaccggtt actcccaagt cctttaatac
    10681 ggattcgata ttcatctgaa ccataaagct agaccctaag cctgaaccac aggctgtacc
    10741 aattcttaat gccattttat gcctcctctg caataatagt tttaatatcc tcaaatgatt
    10801 tagacgcaag taaagccttg acctgctcat tgtctcttaa aatggtcgtc agccgagaca
    10861 gggcctttag atgtgtttca ttatcaatag cagcaataca aattaacaaa cgaatctcct
    10921 gcttaggatc atctaacaaa taaatcgggt gctctaaaac aagcatcgac atacctacct
    10981 gattcacacc atcctctggc ctcgcatgtg ggatagcaat ccccttacct agattaataa
    11041 aagtaccaaa ctcctcaacc ttagcaatca tagcctccgg gtagctcgct tgaatctgcc
    11101 cactctctaa caagggctga gccgccaaat aaatagcctc tctccacccc aattgctctg
    11161 aggttgattg ataggttttc ttggtaatta agtcttgtaa cactggtcga atatcctttc
    11221 ttttcacacc ttgtcttaaa tattgctgca aagcaaagcg cagcttttct ttttgatgaa
    11281 tgaccgcata tgagctgata agatggagca gctcttcaac ctctagccga tagccaatat
    11341 ctggaaaatc acgattaacc aagctgacca gctgaaaagc ctgctcatca gtcattatca
    11401 tagggactaa ataaaagggc ttatcagtct ctaatcgtat cgttgaaaaa accaaatcat
    11461 agccgctctt atctaattgc ccaagctgat caagccttga aagcccccga aaagcaatat
    11521 caggaaataa aagctttaaa tgctccttga tcattaaaga agaactaaca ccattaggac
    11581 agacaatcac agcctgatag gcttgacgat gaaaatctct tccctgctgc tttaaatagc
    11641 ctccaaaatg aagaacaaaa taagcaattt cactatctgg tataggacta cccagctcct
    11701 tggctaaagg ctccagagac tgctttacca agtcaaaaag ctcagaataa ctatccttaa
    11761 tccgcaaggt ataatcatta tcacttggca aaccatagcg caaacggtaa taggctggaa
    11821 tcaaatgcct tttcaaattc tccttgagct gatctgcctg actaaagctt agtaaagcaa
    11881 ccccctgcat ttgatcaaca atcgcaacgg ttagtgattc aaagaaatca tcaccaacag
    11941 taccctcacc ctcaaagcag cccgctaaca gcaattgaaa ataggcctca tcagcttcaa
    12001 atagctgata cttaagagac aattgctgca ttatttctgc caccaaaagg gccgttagct
    12061 gatccagctg ctcagaaacc actacctgtc tttgcttgac cctatcaacc cgtctttggt
    12121 aacgacataa aataaagatg acagcgtaca aacagacctg cagacgatca aggatcggag
    12181 acatctgaaa ggtctgataa aaatggctca cacgtttttc aagcgcttca aacgacacct
    12241 gatagtgcca agaagccaaa atatagtcca aggcccacaa gccaatagga gatttaagca
    12301 aagtagcaat cattactaaa gccaaccggt gcttattaat ctcatcacca actaagatat
    12361 agccgcttgc tctggtatac tttaattcca agtcaacatc tgccagcttc tgccgcaagg
    12421 ccttaatatc tgtcaaggct gtgttcttgc tgacctttaa aaagtcctga taatgactat
    12481 ttgaaacaaa atccctgcgg caaaaggtat acagatagat aagattgatc cgctctgcct
    12541 gagaaagata aacctgctca gcattaatca acgtaaacaa atgatctgac tcagccttaa
    12601 gctgctgact gatccgatag ccagaccttg ttgcatctag ctctgagagc tcatgctgag
    12661 ccaaaaactc attcagctca tcaatacggt ccttaatctc tctaatggtg aattttgtct
    12721 taacactcag ctcgtaaagt gataagtctt gataagtcat caacgtcatc aaaatgacaa
    12781 ctgctttgct atcaaccatt tgatttcctt tctaaattca ttctatcgaa aacggttaca
    12841 ataaactagt ccccattggg cacaatttct tatccaacat catcaacagc ccttgggctc
    12901 aagatgccaa tctaaacagg ctaccagctc ctcctaacta tcaataaaga gcaaacaagc
    12961 ccatctctgc cgctaagcaa ttgtccccat gatttcctaa gtccaagcca aagctaaagc
    13021 tctttggagt aataaccgtc aaaaatgttc caaataatca aaaaaactga ttgacctcat
    13081 cagcatgtga taactctaga tataagccta aaacaagatt acagacttaa tagttaactg
    13141 gtaatctttt attataccac ga
//
LOCUS       DARYVE010000055        12984 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYVE010000055 DARYVE010000000
VERSION     DARYVE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12984
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVW25_001548"
     CDS             complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVW25_001548"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1379166.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1338..2401
                     /locus_tag="TVW25_001549"
                     /pseudo
     CDS             1338..2401
                     /locus_tag="TVW25_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVW25_001550"
     CDS             complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVW25_001550"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1379167.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3364..4059)
                     /locus_tag="TVW25_001551"
     CDS             complement(3364..4059)
                     /locus_tag="TVW25_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1379168.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4212..5615)
                     /locus_tag="TVW25_001552"
     CDS             complement(4212..5615)
                     /locus_tag="TVW25_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1379169.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5997..6341
                     /locus_tag="TVW25_001553"
     CDS             5997..6341
                     /locus_tag="TVW25_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379170.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6359..6754
                     /locus_tag="TVW25_001554"
     CDS             6359..6754
                     /locus_tag="TVW25_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1379171.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6804..7925
                     /locus_tag="TVW25_001555"
     CDS             6804..7925
                     /locus_tag="TVW25_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1379172.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8107..8415
                     /gene="citD"
                     /locus_tag="TVW25_001556"
     CDS             8107..8415
                     /gene="citD"
                     /locus_tag="TVW25_001556"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1379173.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8403..9290
                     /gene="citE"
                     /locus_tag="TVW25_001557"
     CDS             8403..9290
                     /gene="citE"
                     /locus_tag="TVW25_001557"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1379174.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9292..10824
                     /gene="citF"
                     /locus_tag="TVW25_001558"
     CDS             9292..10824
                     /gene="citF"
                     /locus_tag="TVW25_001558"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1379175.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10817..11377
                     /gene="citX"
                     /locus_tag="TVW25_001559"
     CDS             10817..11377
                     /gene="citX"
                     /locus_tag="TVW25_001559"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1379176.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11408..12799
                     /locus_tag="TVW25_001560"
     CDS             11408..12799
                     /locus_tag="TVW25_001560"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1379177.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3802 a         2590 c         2874 g         3718 t
ORIGIN      
        1 tagagagggg gtagttgttg gttaataatg cttaaggtct gttgctgctt tgatcttagt
       61 tatcgtgggc tgagcagcct cgctcctaaa aaagtcaagt gaggtcttag gaaggagtag
      121 ctctaagaga gcataatcat cgtccttgat ggcctgtctg gcaagagagg cgctgatgat
      181 tttgccttct gcaaaggttt ttctagggat aacctgcaca tcaatgctat agcaaggcag
      241 ctgcttgagc atgacagtgt tgtaatgctg tgtgaccatg ctagtaggct cttcgccaac
      301 ataacgactc ttgatttgga gtttttctgc aatgtgacgg aaaatgacaa tatccaattt
      361 agcttgacta tcaataactg ctagctcatc tttttgaaaa taagcaggaa aggttgcctg
      421 actaatcatg taaggtccac tatcgtggta tatgatattt gctaggtgtg cagttccttt
      481 gatgattaat tcctttcgga tatggtaggg gatcaggcta ctgtcttgac tgaccataaa
      541 gagatgaacg agctcgttgt cagcgcaggc cttttcaatc agatgcagat gaccaagggt
      601 aaatggatta gcatttaaaa cgattgctgc ggtcttttga ggactgatct ggggcttttc
      661 tagctgtgac aggtagtgct caaagcccct ttttttattt tctaaaaaac aaagagtatc
      721 atcaaccatt gcaatgacat gaaagccaag acttagcaat agaggggcag ctgctatttt
      781 agtgtagata aacagatgat gatgcccacg tgagtaggcc tcctcaatca gatgtgagac
      841 aatgtgatta agtaagcctt ctccttggta ggcttgatca acagctaagc agcgcaggct
      901 attgccgtac aaagagccag tagcaatagg ctcgccttgc tcgtcaataa tagcacaggt
      961 ataatctaaa tgagggtctc ttctaatgtg ctgtctttgt aacaaacgat caatttttgc
     1021 tttttgctgc ttgtcaaagg gaaaaatatg ctgtatcaag tgctgcgtca tatgctcacc
     1081 tcttattacg aaattatcct cttgccttta ttatagcacg ctatagggct tattcttaag
     1141 catcttagct ggtttatgaa aagaatgcac aaaaaagaca tcaatgacct attgtctctg
     1201 atgtcattat gatatgatta ggacttttag ataaatgatt aaggtatgga ggatttaagc
     1261 ctgcaaaagg tggcaataat aattctgact tatgctataa tagagctatt gatattaagg
     1321 gggataaagg ggctggtatg ctttcgattc taatgacttt atttgttggg acgctgggag
     1381 ggcttgttgc taagcggctg agtattcctg ccccttttat gattggcagt atggtagctg
     1441 ttgccctagc ttctatcctg acaaagcagg tagaggctat taaccccatg aagatttttg
     1501 ctcagattat tagtggtgcc tatattggcc aaagcgtcag caaatctgac ctgcttaatc
     1561 tgcccaagct agccaagtct attattagtc tcatgtcctt gttcacgctg aatatgtttc
     1621 ttcttggtgg ggtatttgtt tactgctttg atcttgatcc tgtaacagcc ttgttgagct
     1681 gtttacctgg tggcattatg gacgtttctc ttatggcagt tgatatggga gcaaaggctg
     1741 atatagttgc gacattacag tcggctcgac tggtcggtat gctcttgttt cttcctgttt
     1801 gggtgacgtt ttgggtcaat cgctttgacc caaaagcaaa agctactaaa aaaaaaagat
     1861 agtcaaaagc gctagctccc aagatacaag accttctagg aaagagcagc tatggaataa
     1921 tgtccaggtt ttaagcattg ctaccattgg aggtttgatc ggtttagggc taaagatacc
     1981 tgtaggcgct ctgattgttt ctttgctttt ttcaacagca ctgaaggtgc ttcggcaaac
     2041 aagtcaaatg ccaagtacac ttcgttatat agcgcaggtt tttgctggct ctattattgg
     2101 aacaagcttt actcaggata gtttgcttca aatgggacgt ctgattgttc ctattctttt
     2161 acttttgagt agctatctga tcatcaatct cttttttggc tatatcatgt ataaaaaagg
     2221 tatcttggat ttgcaatcgg cactctttgc ctcatcgcct gctggtgcga cagacatttc
     2281 actattggct ggtgagcttg gcggagatat gcctaaaatc gctggtattc aaatcagtcg
     2341 aaccctctat actgttgtca tcatgccctt gttggttaaa tggctcatta gtatatggta
     2401 aacagaaaag cccctcagag cataaaccag agatacctag tcattaccaa ataacatatc
     2461 aaggatcttg ttcaggcttg gagctgctat aattgatttt ctaaaaaagc aaagtagagg
     2521 cttagcacta gcagatcagc agtccctcca ggactgagat gcttttggat cagcttgtcg
     2581 ttgtaggctg acaaggcagc ctttaagtca gcagtgctca aagagctgtt gtgcaatagc
     2641 agcatgtcct gtttgacttg ccgccaagct ttgatgcctc ctcggtgaat caggttgcca
     2701 tcttccacaa tagacatgag gtaaaccagc agttgcagtt gagcggtctc ctgatcagtg
     2761 ctgcgaaggc tcttgcgcaa aaaaggcagc gccttgtgag caattgtagg atagccctcg
     2821 ctggcttctc ctctagggcc ctttataccg taatctagaa agagcttctc accataggtg
     2881 agctcttttt ttaggtctaa gctaccaaaa tcagtctcaa ggagatgagc tgttagaggc
     2941 ttgacaagct gacaaatagc cagactatcc tcctcagtaa aggctgttac atggtccaag
     3001 agctgtggtt gatcggcaag atacattccc gttgccccaa gcagaagtgc taaggaaaaa
     3061 ttgactccct tatgggtatt gactccctta gttgcgctga acatggcttg ctcagcctca
     3121 atgcctgagg cacgcaagcg ctcaaagatc agaccaggat cttccttagc atggtaaaaa
     3181 ccaatgtcta aataaatctt aaaaaagggg gctaaggcca gagcgctatc aacaaaggtt
     3241 aagaagctca tgtcatcatg agccccgtta tcaagctgat ccacaagccc aggcttagga
     3301 gataaggaca cttcgtaaag taaagccttt agagcaagcc tgctaatatc atcaaatacc
     3361 ttcttagtca tcctgacgcc tgctcatttc ctgtaggata aattctagtg agctgttgag
     3421 gtgctcatgc gtaataaggg tgatttgctc gtggtcacga tttttcatgc cacgataaat
     3481 catccaatgc tcagataaag cgcgttttcg tctttctagg gaagagatcg aaatttttct
     3541 aaagtaaaca aggtaggtct gcaattcagt gacaatttct tttaatctga ccatctgact
     3601 atagctgtaa atcagattat taaagctgtt gaaattatct agaattctgt tgagatcgtc
     3661 atcttctata aaggtttcac aatcagccaa caaatcatgc atgacctgaa aatcttcctc
     3721 tgtcatcaaa tacatagcgg tgcttgttgc cagtgtttca agcgcttttc tgatttcaaa
     3781 gatttcacaa gcatcttgaa tactaacacc cttgacaata atgccttttt taggaatatg
     3841 ctctaccaaa tgctcctctg ataacaatcc tagagcgtac ctgattggtg ttctgctaat
     3901 atttagggca atggaaaatt ctttttcgtt gatacgactg ccagcaggaa tttgtcttaa
     3961 aataatagtt ttctttaggg cgttataaaa agctattttc aaagggatat tgcgggatag
     4021 gtcaagatta ttctttactg cttcgataat aggattcata taatctcctt aatgttcata
     4081 tcatgatatt attatactga aaatcattac taatgaaaat aataattagc ctcctaaaag
     4141 gcgaaagcca tgctcgtgaa agaacatggc tttcattagc ccacactaca gtcctaataa
     4201 tagctcgtga cctattgtgg aatgtaaagc ggcatttgtc ccattgcaat aatggttaca
     4261 acaaagataa taaagataat aatcgcgtat ttagcagctt ctttttgcca ttctcccata
     4321 tcaagcccag taagacgaag aagcaggtaa ataaaggcca ccaatggact gagcaaatgg
     4381 aaggcttgtc ccatcagaga agcaagagcc atcgccatgt tgctaaagcc atattcagct
     4441 ccagcctccg ctaagactgg caaaatacca tagtagaagc catcatttga gataaagaaa
     4501 gtaccaggag ctgaaatcag ggcaataaca agtccccaga agccagccaa ttgctttgga
     4561 ataatcgttg caaagctttg agcaagagca ctagccatac cagagccttg gaaaagtccc
     4621 atgaagatac cagcagcaaa aaccagaata acaacctgaa cagcatcacc ggcattatca
     4681 ccaatacgct ttgtttggtc ctttaggaca ggatagttaa caataagggc aatacaggtt
     4741 cccactgcaa ataaaagaag tggtgccata gcaatagcct tatagaaaga gccagcaacc
     4801 agccaagtga ttaagccgat ggttaagata gcattaaagg caaagttttt aggacgacgg
     4861 atagaaagcg tatctggatc tgtaatgtct gttagcttac gcatttcctc ttcggtcaaa
     4921 tcaacaacac caagtcttgc acgctccttg cgtcccatgc ttggcgcaac ccaacaaatg
     4981 acataaagaa gagacaaaac cataccaggt gcaaggtatc caaggatttc aggtcccaca
     5041 ctaagcacag acatggcacg cgcagttgga ccaccccaag gaagcaggtt catgatagtg
     5101 ttttgcagga taatcaagac accaagattc atgatgcgca tgtttaattt cttatagatt
     5161 ggtaaaaaag cagagcagca aatcaaggtt gttgttgtac catcaccatt aagtgaaaca
     5221 gctgctgcaa caattgcagt tgccatcaag accttcatcg ggtctccctt agcaaagcga
     5281 atcatttttt cagtaatcgg gtcaaacaag ccagcatcta gcataatgga aaagaacagg
     5341 atcgcaaaaa gcagcataat acctgtctta gcagtgttat taataccgta catgatcata
     5401 ggaccaatag ctgtcagatt tttagcaagc ccatcctcac caacaaaggc aacaaatttg
     5461 gcgtctgatg taaaatcagc agagcctgtt aatataacag caattgtcat tatcaacgga
     5521 atcatgacca gagctgtaaa aggggtcatt tttttcttca tgacgacata catgaagata
     5581 ataatcatag cataagctag aactgttaat aacatattgt tatctccttt ttgattttat
     5641 gacttcagta taaatgaaag cgttcgcaaa agaaatacct ccatgtacgg aaaaacacaa
     5701 aaaaaacatt ttgaaagcag atcctgaaaa aataaatggt tacattaatg tttttcaaca
     5761 gcagttagtt gctcttatct tcagtaatcg cagtgtgttt cagcattttt taaaatcagt
     5821 catatttatt ttagttaact gtttttataa aaatggttaa ctaaaataag aaaatccttg
     5881 aaaatgtgaa agcgctctta gaaagaacac aaaaaagcca ttccaaaagg atgaggtggt
     5941 atataataag catagaagct tcccatttgt gggcaaacta agaaaggagg tagcttatgc
     6001 agttttttca aaacatgttt agacgctcta aaaaagaggc agccacaagc catcaagaca
     6061 gagaaaataa gcctgaattt ccgttagatg actgggagcc agtgcctagc tacattgctg
     6121 cagataaaaa ggattatcag acagttagtc tgattgccag tgccattgca gctggcgagc
     6181 aagctagcag tcagtttaag gtaaaacgaa tcctacagcg caatcctgag gccttaaccg
     6241 tatccttaat agcatcaagc attgcagctg gtgtttatcc agagagtcaa tttctggtta
     6301 ggtccattta tagtaagaaa gtaaacgtta gccacaaata gtaaaaggag aaaagattat
     6361 gttgcgtaag tttaaaatta ccattgacgg aaaagagtac ctagttgaaa tggaagaaat
     6421 cggtgctccc tcccaagccc cagtagtacc tcctgttcaa ccagcagtag ctccagcccc
     6481 tgtagccgaa aaaaaggcag cagaagctcc gcaagctcca gcagcacctg tatcagcagg
     6541 ggcagatgca atgccctcac ctatgcctgg tattatctta aaggttttag ttaatgttgg
     6601 tgatgtcgta catgaaaatc agcctctatt gattttagag gctatgaaaa tggaaaatga
     6661 gattgtcgcc tcaacagctg gtacagtcac agggattcat gttactgcag gtcaggtggt
     6721 caaccctggt gaaggcttaa tcaccattag ctaatcctaa gtcgtgtctt gatttaaaat
     6781 gttgtagaaa aggaagtaca tttgtggaaa cattaattgc aggagtaacc tccatcacta
     6841 ttcctcaaat cattatgatg cttatcggtg ctgtcttaat gtatctagga ataaaaaaag
     6901 aatacgaacc aaccttacta gttcccatgg gactgggtac tattttagtc aactttcccg
     6961 gcacaggagt cttaacacag gttgttaatg gtgttgagca agaaggggtc tttgatgcct
     7021 tattcaattt tggaatcggt acagagctgt ttccattact tatttttatc ggtattggtg
     7081 ccatgattga ctttggtcct ttacttcaaa atcctttcat gctattattc ggtgcggcag
     7141 ctcaatttgg gattttcttt gttgtcgttg tagccgtatt agctggcttt gatattaagg
     7201 aagcagcttc aattggtatc attggtgctg ctgacggtcc aacatcaatt tttgtagcaa
     7261 accaattggc aaaggatttg ctagggccta tcacagtggc agcttattct tacatggctt
     7321 tggttccgat cattcagccc tttgcgatca agctagttac taccaaaaaa gagcgtcgta
     7381 ttcgtatgac ctataaggct gagaatgtgt cacaattaac gaagatcctc tttcctattg
     7441 tgatcacact tgtagccggc tttattgctc caatttcgtt accattggtt ggttttttga
     7501 tgtttgggaa cctgcttcgt gaatgtggtg tcttggaccg attgtcacag accgctcaaa
     7561 acgaattggt caatatcatc agtattttac taggactaac catctctatc aaaatgcagg
     7621 ccgagctttt cttgaatgtg caaaccctgc ttattatcat ttttggtctg ttggccttta
     7681 tcatggattc gattggtggt gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa
     7741 aaatcaaccc aatgatcgga gctgctggaa tttcagcctt tccaatgtca agtcgtgtga
     7801 ttcaaaaaat ggccactgat gaggatccgc agaatttcat cttgatgtat gctgtgggtg
     7861 ctaatgtatc tggtcaaatc gcctcagtta ttgcaggtgg cttgctgctt gcttacttta
     7921 gctaagaaag gacgtgctta tgacaatcaa tatagaccat ttgatccaat cctttgagct
     7981 aatggcactt ggaatggcag gagtatttgt tgtattagga attctctata ttgtagcaga
     8041 ggctctgatt aagctatttc cagtagaaaa ataatagaat atgatctaaa caaggaggtc
     8101 aatcaaatgg agatcaaaca aattgctgtt gctggttcgc ttgaatctag cgacatgatg
     8161 ataacaatat cacctaatga tggtcaggga atcgttttgg aattggattc aagcgttgaa
     8221 aaacaatttg gcaatcatat cagagcatta atcaagacaa cacttgccag gctgggcgtt
     8281 gagtcagcaa cgatcgaagc tgttgataag ggagccttgg attgtaccat tcaggcaaga
     8341 acaattgcag cagtccatcg tgctgctgga gttgagcatt acaactggaa ggagatcgac
     8401 tcatggaacg cttaagaaga acgatgatgt ttgttccggg cgctaatgcg gctatgctaa
     8461 gagatgcacc cttgtttgga gcggactcta tcatgtttga tttagaggat tcagtttcct
     8521 taaaagaaaa agacacctct cgcgcccttg ttcattttgc cctaaaaacc tttgattatt
     8581 caaatgttga gacagttgtg cgcgttaata gcctagactc ttgtggtgct ctggatattg
     8641 aggcagttgt gttagcaggt gttgatgtta ttcgcttgcc aaagacagaa actgcccagg
     8701 atattattga tgttgaggca gtcattgagc gtgttgagcg tgacaatggg attgctgttg
     8761 gtcgtacacg catgatggca gctatcgagt ctgcagaagg ggtcttaaaa gctcgtgaga
     8821 ttgcaaaggc ctcaaatcgt ctcattggta ttgccctcgg cgcagaggat tatgtgacta
     8881 atatgaaaac acgtcgctac ccagatggac aagaattatt ctttgcccgc agcatgattc
     8941 ttcacgcagc acgtgctgct gggattgcag caattgatac cgtttattca gatgtcaaca
     9001 atacagaagg cttccaagct gaggtgcgtc atatcaagca attaggcttt gatggtaaat
     9061 ctgtcatcaa ccctcgtcag attccattgg taaatgagat ttatacacca accgaaaaag
     9121 agattagtca cgccaagcaa gtgatctggg ccattcgtga ggctgaaagt aagggatcag
     9181 gtgtcatttc attaaatgga aaaatggtag ataagccaat cgtagagcgt gcacagcgtg
     9241 ttatcgcttt ggcaacagct gctggggtat taacagagga ggacatttag catggttaaa
     9301 aataaacttg gtcgtgatat tcctcaggag tatgctgatc actatggagt atttgaagga
     9361 gagctagcac gtatcactag ctacaatgaa tcaagccgcc gcattaagcc tgtaaagcca
     9421 ggtgacagta aattgcttgg ctctattcgt gaagctattg aaaagacagg cctaaaagat
     9481 ggcatgacca tttcatttca ccatcatttt cgtgaggggg acttcgtcat gaatatggtt
     9541 cttgatgaga tagccagcat gggaatcaaa gatttagcta ttgctccaag ctctattgcc
     9601 aatgtgcatg agccattaat tgagcacatt aaaaacggag tggttacaag cattacctca
     9661 tcaggtttac gtgataaggt tggggcagct atttcatcag ggattatgga aaagcctgtt
     9721 gtgattcgtt ctcatggagg acgtgctcgt gcgattgcta gtggtgatat tcatattgac
     9781 gttgcctttt taggagcacc aagctcagat gaatatggta atgtcaacgg tacgattggt
     9841 aaggctacct gcggctcact tggctatgct atgatcgatg ccaagtacgc agatcaggtg
     9901 gtggtgctga cagatcacct agttgattat cctaacaccc caattagcat tccgcaaact
     9961 gatgttgatt atgtcgtgac agttgatgct attggtgatc cacaaggaat cgctaaggga
    10021 gcaacgcggt tcaccaaaaa tcctaaggag ctcctaattg ccgaatatgc cgctaaggtt
    10081 atcacacagt cgccttactt taaaaatggc ttttccttcc aaacaggtac aggaggagct
    10141 tccttagcag tgactaggtt catgcgtgag gccatgcttc aagaaaatat caaggcaagc
    10201 tttgcccttg gaggcattac aaacgctatg gtagaattgc tcgaagaagg attagttgag
    10261 aaaatcctag atgtacagga ttttgattac ccttcagcag tttcgcttgg taaaaatgct
    10321 cagcattacg aaattgatgc taacatgtat gcctcaccac taagcaaggg atcggttatc
    10381 aatcaattag acacctgtat tttatcagcg cttgaggttg acactaattt caatgttaat
    10441 gtcatgacag gttctgacgg tgttattcgt ggggcttccg gagggcattg tgacacagcc
    10501 tttgctgcca aaatgagtct ggtgatttca ccccttatcc gcggacgcat tccaaccttt
    10561 gtagatgagg taaatacagt aattacacct ggaacaagcg ttgatgtggt tgtcacagaa
    10621 ataggtattg ctatcaatcc aaaccgtcca gatttgatag agcatttcaa ggacttgaag
    10681 gttcctcaat ttagtatcga agaattaaaa gaaaaggctt actcgattgt tggaacacct
    10741 gatcgtatcc aatacggtga taaggttgta gctcttattg agtatcgtga tggcagcctg
    10801 attgacgttg tctacaatgt ctaaggaatt gattttcaag gggaaagctg ttaccctagc
    10861 tgatatgcta agggcacgcg aggacagaag ccttcgtcaa ggaaagcttt taacagaatt
    10921 ctcaaacgaa agcctgcttt ctgtgaccat gaatattcca ggccccatta aaacgtcacc
    10981 tgctttactt gaggtatttg atagtgttat caaggcaatc ctagaaaagc tgtctggcaa
    11041 tcagatcagc tatcagcttc gtttgctgcc aaaaacgggt tatgaatatt accttgtgac
    11101 agccttagat agtcaggcat taaagctcaa aatgattgag cttgagactg atttaccgat
    11161 tggcaggcta atggatttgg acgttttagt gctgacaaat cagctgccaa cccctatcag
    11221 tcgaacagcc ttaggctttc ctcctcgcag ctgctatctt tgctcaaaag aggctaaggc
    11281 ttgtagtaga aatcgcagtc actcggtagc agacatgcag acagcccttg tacacttact
    11341 ccaatcattt tttgacggag gcaatcagct cagttagact caacggtatt cttataagga
    11401 gaatgatatg acaaaaatcc gtataacaga aacagttttg cgtgatggtc agcaaagtca
    11461 aattgctacc cgcatgacta caaaggaaat gattccgatt ttagaaacac tagataatgc
    11521 tggctatcat gccctagaaa tgtggggagg agctaccttt gattcttgcc tacgtttctt
    11581 aaatgaagac ccttgggagc gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt
    11641 acaaatgctc ctgcgtgggc aaaatctttt gggctatcgt aattatgctg acgatgtcgt
    11701 ccgcagcttt atccaaaaat caattgaaaa cggtattgat attgtgcgca tttttgatgc
    11761 cctaaatgat ccacgtaatc tagagacagc tgtttcagca acaaaagaat tcggtggcca
    11821 tgcacaggtt gctatttctt acacaacaag tccagttcat actatcgatt attttgtagc
    11881 cttagcaaaa gcctatcagg ctattggtgc agattcgatt tgtatcaagg atatggctgg
    11941 tgtgttaacc ccggagaccg gttatcaatt agtgaagcgt atcaaggaaa gcattgctct
    12001 accacttgag gttcacacgc atgctaccag tggtatttct gaaatgacct atctcaaggt
    12061 cgtagaggct ggtgcagata ttattgatac tgccatatcc tcatttgccg gcgggacaag
    12121 ccagccagca acagaatcga tggttattgc tttagaggac ttggggattg ataccggagt
    12181 agacatgaca aggctgacaa aaattgccga gtattttaat actatccgag atcactacag
    12241 ggcagagggc attttaaatc ccaaggttaa agacactgag cctaagacct tgctttatca
    12301 ggttcctggc ggcatgctgt ccaatttgct aagtcagctt aaggaacagg gactctctga
    12361 caaatatgaa gaggttctgg ctgaggttcc aaaggttaga gctgatttag gctacccccc
    12421 actggtgact ccgctatcgc aaatggttgg cacacaggcc ttaatgaatg ttatttcagg
    12481 tgaacgctac aaggttgtcc caaacgaaat caaagactat gtcagaggac tttatggcca
    12541 acctcctgcg ccactaggtg aaggtattaa agagaaaatc attggtgatg aagctgttat
    12601 cacttgtcgt ccagcagatt tgattgagcc acaattgccc ttgcttcgtc aagaaattgc
    12661 aggctatgcc tgctgtgagg aggatgtgct gagctatgcc tctttccctc agcaggcaaa
    12721 ggatttccta ggacgcagag aggatccctt ttatgatatc ccagttcagt acgtcaccgt
    12781 tgatatagca atggattaat caaaagaata aaaagcaaga taactaataa aatcaatctc
    12841 ctaattatta gtcaaagcta cctaccaata aactccttaa tcagaaccac ccgtctaatg
    12901 aggtgccccc aaaaggttag tccaaaactt taggctccat gtcaactgta gtgggtagtt
    12961 gacaagctaa catctggaga ggac
//
LOCUS       DARYVE010000056        12358 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYVE010000056 DARYVE010000000
VERSION     DARYVE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12358
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TVW25_001561"
     CDS             complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TVW25_001561"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1379178.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2577..3230)
                     /locus_tag="TVW25_001562"
     CDS             complement(2577..3230)
                     /locus_tag="TVW25_001562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379179.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3270..3899)
                     /locus_tag="TVW25_001563"
     CDS             complement(3270..3899)
                     /locus_tag="TVW25_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1379180.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3901..4902)
                     /locus_tag="TVW25_001564"
     CDS             complement(3901..4902)
                     /locus_tag="TVW25_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1379181.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4935..5576)
                     /locus_tag="TVW25_001565"
     CDS             complement(4935..5576)
                     /locus_tag="TVW25_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1379182.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5611..6405)
                     /locus_tag="TVW25_001566"
     CDS             complement(5611..6405)
                     /locus_tag="TVW25_001566"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1379183.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6714..7148
                     /locus_tag="TVW25_001567"
     CDS             6714..7148
                     /locus_tag="TVW25_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1379184.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            7148..8347
                     /locus_tag="TVW25_001568"
     CDS             7148..8347
                     /locus_tag="TVW25_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1379185.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8393..8881
                     /locus_tag="TVW25_001569"
     CDS             8393..8881
                     /locus_tag="TVW25_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1379186.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8896..9675
                     /locus_tag="TVW25_001570"
     CDS             8896..9675
                     /locus_tag="TVW25_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1379187.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9662..10483
                     /locus_tag="TVW25_001571"
     CDS             9662..10483
                     /locus_tag="TVW25_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1379188.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10883..11884
                     /locus_tag="TVW25_001572"
     CDS             10883..11884
                     /locus_tag="TVW25_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1379189.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3477 a         2845 c         2448 g         3588 t
ORIGIN      
        1 gctcaggggg gattttaact tattactaat gtgcttgaat ggctatgata aggccttaaa
       61 agatagctgc ttaaagtcat ttcccacctt ttgatagagg tataagcctg atttttcaag
      121 actcaattga ccattaacca cctccttagc ctgattgtat ttgaccaccg ccaacaggcc
      181 ttgtttctta tcatggatca gctgaagctt actgtcattt cgaagcacct caatacgtgc
      241 ttcgctgcac accttgtcaa agtctgcttt gctgatattt ggaagtaggg tgtaggcata
      301 gctatcacta gcctgagaat gagtttgact gattgtgata aagctttggg agatgaggtc
      361 tttattgtta ctatttgtat taatctcaga ccaacagcct gactgcacct ttcgcgatag
      421 cgctaatgcg gttggcttgg caaaaaggta accaatatta gcttgaccgt ctttagaaag
      481 tagtaaaaga ctggtcacat catctcgata caggatctcc tctgttagcg ctgtctcctg
      541 cccattgata aaaagagtgt agctgttgtc tgggttttct ttgcgttgat caatggtagt
      601 agtcactgcc tgatgtgtct gactagtgat ggcggtgcca agaaaaacaa tttggtcatc
      661 taagatcgtc caagacttct tggcactcac tgtcctatcc caattttgaa aatccataac
      721 agctaaagct gttttgtctc ccgccttgat cgctccaaca aaggacgatg gcagggtaga
      781 catgcctgct ttttctttgg ccttttcttt ataatcattg gttagctttt ttaaataggc
      841 tactgtcacg tcctctcgcc tgacctctgc ttccgttgtt ccagccatct ttaaaggatt
      901 aacagtcggc caaaagtggt ctgagtaatg acccaaatca ctgttataaa ggtaaaacat
      961 gccatctcct gtataccaac cacgtgtatt ttcatcgttc atggcttcaa aattcagagt
     1021 tttgttggaa tgcatggata aagcaaaggc aaaatccttt tccgcattgt agtaggccaa
     1081 tttatccatc tggttaaaaa gagataggta gctcttaact ggactggctt ggattgtggt
     1141 atcctccaag agctctttga atagcttcat gtcatagtag cttgataggc tctctaaaat
     1201 agtctcctga ttatggaagg ccaaaacagc cttgatctta cccttgatcc tgattttagc
     1261 ttgctctggc aatgcctcag ccagtcttag cattcctctt agtgcttcta aggctgcctg
     1321 ccttgaggag gcattttcac gactgatgga gcgcccacga ctcatatcca tgagctcccc
     1381 atgaaccatc aagggcaaga aggcttgctc aatccaatga gtcatgacct ctagcttttg
     1441 ctggtctagg ctagtagcta atagctgaag taatggtacc agctgagaca agccatcaat
     1501 aaggacattg ccataggctc cagtgtaggc gacattggta tggtcaatat aagagccatc
     1561 ttcataaaag ccctcacccc ttgatccctt tggctgaaaa gcaaataagg tatctagggc
     1621 tgctatactg tcttgaagcg ctttcttatc atgctttaac agagcttcaa taatcttcac
     1681 tcgtcccata tcaacaaggt tacccccaat ggccttaaaa ggattcacaa gggttaagcg
     1741 aaattgtcta ggattaggaa caaagtgaga aattccttta gtatagcgct tgatctcctc
     1801 ttgagtgaca taagggtaaa tgaaggctag ggtattgaca atagctcttg gggtaccaat
     1861 ttcaaaatcc caccaattag ccttgccttc aatatccttt tgcggatgat agtaattaag
     1921 tgtcagccag gctaatttat ccttgatcag tcttatcagc tccttatcct gataatacct
     1981 agaggctagg ctactcacct gcttggccat ttcctctaaa cgcctacagg tagctgtcat
     2041 atgagacgat tgatgaagat ccgccaaatc actccaaagg tatgtgcttt tctgatcctt
     2101 ggtcagatca gctagattct tggtcacgct gtcgtccagt ttttggttta atgccaccat
     2161 ggctggactt gatcggtcaa agttttctgc tcccaaaatc acctcacacc actttgtgat
     2221 caaggaggtt gtttgagggg cttctgctgc taaaatctca actggtaccg ttgctactct
     2281 ttgcccctct tgatccaaca cctctaaaag cgttttcccc tgcgccaaag gaattaaaag
     2341 accattttcc acgcgcacaa tgttgctgga ctccgctgca atctgataat gatagtcagc
     2401 catttccatg aggtagtgct tatttaaagg caggacgatt tgctcctcta agtaatgtga
     2461 agcaatcttg atgtcatcac ttggcttatc accagcctct ctcaaagaaa ggttatcaaa
     2521 gaccacctgt ccatgaccgg cctcataaaa gagctctagc ttgatttgat taacctttag
     2581 cttagggata taaagctttt cttggtgttt tttctcagtt cctgttgcca tcgaagccac
     2641 aagcgttgct cttttgcagc accagaacct tgctttattt cttcaatgat acgcgcaaaa
     2701 gcctgacctg ttttatcctt tgtctcaatg tcaaaggtca gcaaatactg cttgtctgga
     2761 ttgatggcaa cggtttggtg cacacagcct ctaaatctct gattgccatc gctagtcatt
     2821 gtcagcttgt tatcagagac agcaatttta ggacagccct gactcttact agcgtcctta
     2881 taatccttcc aatcatttgc agactccttg ctccaaaggc ttgtactttg atgctcttga
     2941 gcaggactgg tctgatcaaa ttgaggattt ttaagcaggt tatcacctgt gagaatgagc
     3001 tgctccccaa gactggattc cgtagctact gacgacgcgt cttgagtgtc tggggagctt
     3061 tcttgagaag cctcctcagt ttttagtggt gctttcttta ccctctgaag ctccttggaa
     3121 atggcttttg ctgctgtttt ttcttctgct aagactgttg gtgcccgaaa taaacaagct
     3181 agtatgatac tagagcaaac agaagatgat agtttttttc tttgcttcat ctgatacctc
     3241 cttgcttttt taatgtttta tgaccgactt taacagctac tcatgtaatc tgcagccctt
     3301 gctgtgattg cctgaaattg accctgagct gccaattgat taaattctcc tccaactccc
     3361 agcacctgag cacctgcggc aaaccagtct gacacatttg tgacagttac gccacctgtt
     3421 accatgacat caacctgcgg caaaggagat ttgattgcct taataaagga catgccaact
     3481 gtggcacctg gaaagacctt gaccatctct gcacctgatt ccaaggcagt cacgacctcc
     3541 tcaatagtca tacagcccgg aatataagca atagcatatc gatgacatag gcggcttgtc
     3601 tgcctgctaa agctaggaga cacaataaat tgagcacccg ctaaaatagc tagccttgct
     3661 gtgacatcat caagaaccgt cccagccccg atcaggatct ctggatcatt gccaactgct
     3721 tcacgcaggc ctgcaataac ctgactggca aagggattag tataggccac ctcaatggtt
     3781 ttgatcccac cttcaatacc tgctaggctg caagccattg cttctttttt agaagctccc
     3841 cgaacgacta aggctaattt attggctttt agccttaaca tgatttctga ttttctcata
     3901 ttaccttctt acctctcggt ttcccttcat caccctatca acctgactaa caggaacaaa
     3961 gagctgatca tcagcaactg tacacttaag actagctgtc gcagcagcaa aatcaagcgc
     4021 agcagcaata gcctgtcctc tcatcaattg atataagcag cctgcaacaa aggcatcacc
     4081 actgccaact cgttgcaaaa caggcgttga tagctcaatg gagcgatgta actgcccatc
     4141 ataggcatag gctaggtaat gattgattcc ttggtcatcg atgtgacgtt ccgtgtgaaa
     4201 aatggctttt aagtgatatg cctcatataa ggcagccaag cgctccttga cagcaccttg
     4261 acctgcctta gctctatcaa acatggcatg atcagcttga ttacacatta agggctccat
     4321 accaaagatc aggtctgcat actgtgcaaa atgagagaac aatgtctttg cctccctgac
     4381 tgaaatcatc gagctgcgaa aattcaaatc aaaggaaaca cagacctgcc gcttcattgc
     4441 ctcaatagcc agctgctcaa caaggtcctg actgactttt cctaaagcca aggtaatgcc
     4501 actaaaatga aaatgagtaa cttcctcaaa tagtttacca taatccagat cttttgggcc
     4561 caataaacta aagctagagg cagagcgatc ataagcgacc tgactaggac ggcagccaaa
     4621 gccattttcc aaataataaa taccaacccg atcaccacac cattgcacat gctctgtggc
     4681 aacaccgctt tgcttcaaaa aggcctcaac gcttcgtcca acctgattat caggaagggc
     4741 agtcagcagg ctactctctg ctctaaagcc actaagcgtt cttgcaatat taacctctga
     4801 gccaccataa tacagctgtg cttgacaggc atgtcctaac gtctgaaaat gactgggact
     4861 gatgcgaatc agcggctctc ccaccaataa taccttggtc ataggggtat cctttctata
     4921 gctgcagata agacttattg ctgaaggact tctcttaggt agtcgacaag gtctgatggc
     4981 tcggcattag caaagaaata atgctggaag tgctctccag aaatggtttc cttcaagaaa
     5041 tcttgatcaa tctcctttaa cacctccaac aaagaacgat aagtcacagc cttcaattcg
     5101 ctcaaaattc tagcgttacg ttgctctggg atggcccgct ctttgggata gccgcccccc
     5161 atcggctcag caaataagcg ctcaaacatc agggtcaggt taagctctgc cccccaacca
     5221 aagccctttg caaatggaat agacaaggca ttgccaccat taatctgagc aaaaaggtag
     5281 gcttctgttg gctcactagc aaagccacag gtcacacctg gaaagctatt taaggccagc
     5341 atagcaccca caccagtccc acagcccgtt acaacaaaat cagctgcctt acttgtcaat
     5401 aaaatagaag ctagtagccc gttttgcaca taggtcagct gactttcgcc ctccttgcca
     5461 tacataccat agttaaagac ctcatagcca tgcttattag taacagagac taaggtctcg
     5521 taaataatac tgtttttagc tgcttgactg ttttcattaa ttaatgcaat tttcatcttc
     5581 tgtaatctcc tttgatgctt ttttgtttct ttacggttgt ttgccaatgt aagctaaaat
     5641 gcctccatca acataaagga tatgcccatt gacaaagtta ctcgcctcac tagccaaaaa
     5701 tatagctgga ccagccagat ctgctggtgt tccccaacgc gctgccggag tcttagcaat
     5761 aataaactga tcaaaggggt gacggctgcc atcagcctga cgctctctta aaggtgctgt
     5821 ctgaggcgtt gcaatatagc caggcccaat gccattgcac tggatattgg cttctccaaa
     5881 ttctgaagcg atgtttttgg ttaacatctt aagaccaccc ttagctgccg cataagcact
     5941 aaccgtttca cgaccaagct cactcatcat cgaacagata ttgatgattt tcccatgccc
     6001 ttttttaatc attgatggca gaactgcctt tgaaacaata aatggcgcat tcaggtctat
     6061 atctaccacc tgacgaaaat ccttagccgt catctcaagc atcggtgtcc gtttaatgat
     6121 acctgcatta ttcacaagaa tatcaataat accaacctct ttttcaatct gagccaccat
     6181 ctcttgaatc cctacttcat cagtgacatc acaaacatag ccatgagctt taatgccaaa
     6241 ctctcgataa gctgctaatc cttgatccac taaatcctgc ttgatgtcat taaagacgat
     6301 ctttgctcca gccatggcat aggccttagc aatctcaaag ccaatcccat acgaggctcc
     6361 cgttatcaag gcaattttgc cctctaaaga aaagaaatgt tccattgttt tacctctcaa
     6421 tctcaatatt taagtaaacc tgtttatcaa aactatagca agactaatcc attttgtcaa
     6481 tcattttagt aaaaacacaa aaaagagcta aagtttttct tattgtcatt atcgaggaag
     6541 gcttcttagc tatatttttc ttgctcttac tcgctttact tcctataagg atcccaaaaa
     6601 ttaggccata ttgatcgctt attttgataa aataacaaaa aagtgttgac aaacattttt
     6661 gaaagcgcta taatttttct gagtaaaccg gtaaactaaa aaggagctta ttcatgattt
     6721 ctattattgt tattggtcat gggcattttg ccagtggtat tgtctcgtct ttagagttaa
     6781 ttgcaggcaa gcaagagggc ataactgcta ttgattttac tgctgagatg accgctgctg
     6841 atgtgcatga gcgcctatca gtagtcttac agtcaaagac tcaggcactt atgctttgtg
     6901 acttattagg cggcacccca tttaaggtag cagctacctt gatggaggag ctttctgaga
     6961 gcacacttga tgtcctgtct ggactcaatc tagccatgct aatagaagca gtctttgcta
     7021 ggcaagagca gcttgatcta gaacaaattg tcgctaagct attaaccaca gccaaggaag
     7081 ggatcagtaa ttggaaatcc ctctctggtg aggctgatga agcagacctt gatgaaggag
     7141 ggatttaatg actagacaga tcaaagaggt tacccttgag cctctcatac aagcagaggt
     7201 ctatagccag cagccatatc taacaaaagc tgatattgag gcagctattt tattagccct
     7261 taagcaaatc cgattaaaca tggattattt tggtactgat ttccctaggc cagccactaa
     7321 ggacaattgc tacccaatta tggataatac cgagtggacc aatggctttt ggaccggctg
     7381 cctatggctg gcctacgaat acactggtaa tgacactatc aagtcactag cacaggcaaa
     7441 tgacctgtcc ttcttagaac gcgtcaccaa agacattgag cttgaccatc atgatttagg
     7501 atttctttat tcaccctctt gcatggctga gtggaagctt ttaaaaacac ctgaagccag
     7561 acaggcagcc ttaaaggcag cagataaatt gattgagcgc tatcaggaaa aaggcggctt
     7621 tattcaagcc tggggacaac tcgggaaagc agaagattac cgcttaatta ttgattgtct
     7681 tttaaatatc cagctactct tttttgccag tcaagaaaca ggagatgaca ggtatcgtca
     7741 aatggctatc aatcactttt atgcctcagc caacaatgtg attcgtgatg acgcctctgc
     7801 ttatcatacc ttctactttg accctgaaac aggtgatcca atcaaaggag ttacacgcca
     7861 aggctacagt gatgactccg cctgggccag aggacaagct tggggaatct atggaattcc
     7921 cttgacctat cgcttcttga aggatccaca gctaattgcc ttatttaaag gaatgacgca
     7981 ctatttcctc aatcgcttgc ccaaggatca ggtatcctat tgggatttga tctttgaaga
     8041 tggcagtggt cagtctaagg acagctccgc aactgctatt gctgtttgtg gtattcacga
     8101 gatgttaaaa catttaccag agaatgatcc tgacaagaaa gcttatcaag ctgccatgca
     8161 ctgtatgctc agatcattaa ttgatagcta tgccaacaag gacatcaagc ctggtgctcc
     8221 acttttacgt catggcgttt actcttggca ctctggcaag ggcgttgatg agggaaatat
     8281 ctggggagat tactactatt tagaagccct gctgcgcttt tacaaggact ggacccctta
     8341 ttggtaggct gatagcattt agcctacaaa gactattgtt aaaggagata ttatgacacc
     8401 accaaacatt atcatgacca gagttgatga gcgtttgatt catggtcaag gccagctatg
     8461 gatcaaattt ttaaattgca acactgtcat tgtggctaat gatgccgttg ctgaagacaa
     8521 aatccaacag tctctgatga aacctgtcgt tccatcaagc attgccatgc gctttttttc
     8581 cattcaaaag gtgattgacg tgattcacaa agcaagccct gctcagacaa tctttattgt
     8641 tgttaaggat ttagaagaca tcaagcgctt ggttgaagga ggggtgccca ttaaagaggt
     8701 caatcttgga aacattcata aaacagacga taaaatcgcc attacccaat tcatttcgct
     8761 aggcgacaag gacaaggcta ttattcggac attgactcac gatcatcata ttgtctttaa
     8821 cactaaaaca actccagctg gcaatggtgc ctctgaggtt aatattttag attatattta
     8881 agaaaggaaa ttgatatgga tatcaatttg ttacaagcac ttttaatcgg tctttggaca
     8941 gccttttgtt tcagcggaat gttacttggt atctacacca atcgctgtat cattctgtct
     9001 tttggtgtcg gcattatctt gggggacttg ccaacagcac ttagcatggg agctatatct
     9061 gaattagctt atatgggatt tggtgtcggt gctggtggta ctgtgccacc caacccaatc
     9121 ggacctggta tctttggtac cttgatggct attaccagtg ctggtaaagt tactccggaa
     9181 gctgccttag ctctttcgac accaattgcc gttgctattc aatttcttca aacctttacc
     9241 tatacagctt ttgctggtgc tcctgaaaca gctaaaaaac agcttcaaaa agggaatatt
     9301 aaaggcttta catttgccgc caatggtacc atctgggctt ttgctgtgat tggcttagga
     9361 cttggtttat taggcgcctt gtcaatggat actttacttc atttggttga ttatatccca
     9421 cctgtcctcc taaatggatt aaccgttgct ggtaaaatgc ttcctgctat cggttttgct
     9481 atgattctat ctgttatggc taaaaaagag ctgattcctt ttgtcttaat tggttatgtc
     9541 tgtgcagctt acctgcaaat tccaaccatc ggtattgcca tcataggcat tatcttcgcc
     9601 ctaaatgaat actacaacaa accaaagcat gcaacaacag ctgaacaagg aggtcaacaa
     9661 gatgactgga tctaataagc tcacaaagcg tgattatctg aaaactgctc ttagagcctt
     9721 tttcctgcaa aatggcttta actatagcaa ttatcaagga ataggctatg ccaatgtcgt
     9781 ttacccagcc ctaaaaaagc attttggcaa tgacaaaaca ggcctttaca aagcactaga
     9841 gaacaattgt gcattttaca atacaaaccc tcatttccta ccttttatca ccagcctaca
     9901 cctggtcatg ctagaaaata atcggcctga agaagaaacc cgcaatatca agatggcact
     9961 catgggacct ctagcaggca tcggggatac ccttacgcaa ttttgtttag caccactctt
    10021 ttcgaccatt gctgcttcct tagcaagtga cggcctgatt ttggggccaa ttctcttttt
    10081 cctagccatg aatattattc taacagctat taaaattggc tctggactct atggctacaa
    10141 ggtggggaca agctttattg ataaattaag cgaacaaatg gcaattgtat ctcgcatggc
    10201 aaatattgtc ggagttacag tgattgctgg tctagctgct acttctgtta agatatctgt
    10261 tcccatcaca tttgcagcag gcaaggtcga cgctgcaaat gcagcccaaa aatttgtgac
    10321 cattcaggga atgctggata agattgcacc agctcttctg ccagccctct tcactctctt
    10381 gatgtattac ctcattaaaa cgaaaaaatg gacaacctat aaattagtta ttctaacagt
    10441 tattattggt attgttggca gctggttagg ggtgttagcc tagcagtctt agagattctg
    10501 ttaatcagta ttggagggtc tccattagcg atgagcaggt ctcttttcta ttgggcaaag
    10561 ctaagcattg acaccatcaa ctctcgtagc ctcagtcagg tcttttgccc tgtagagcct
    10621 ttaagcacaa gcctttactg ctagctgtga tgaaggcgtc ctccttctac tggcttctgg
    10681 cacaattaat cctttatatc tctacaagca catgatttag cggctgattg cgcgccaatc
    10741 ttacagaagg tcgcaactta agaaagagta ggatcatttt tgacctcttc aaaggtcata
    10801 ttcttggact gaaatattaa aacaattacc attccatatg ttataataaa actactaatg
    10861 atgacaaaaa ggggtctatg caatgcagcg caaagtaacc atcaatgata ttgctgactt
    10921 agctaaaact tcaaaaacaa ctgtttcttt ctacctcaac ggtcgatttg ataaaatgtc
    10981 tcaggagaca aaaagccgga tcaaggaggc tattgaagcc accaactaca agcctagcat
    11041 tgcagctcgc agtctcaatg ccaaggctac caaattgatc ggtgtggtta tcggtgacat
    11101 caccaatagc ttttccaacc agattgtcaa aggtattgaa agcaaggcgc aagaatttgg
    11161 ttatcagatt atcatcggca acagcaacta tgatccttca cgtgaggacg aattgattga
    11221 aaaaatgctt aacctaggtg tagatggttt tatcattcaa ccaacctcta actttagaaa
    11281 gtattcacgc atcatcgaag tgaaaaaaaa gcgcatggtt ttctttgaca gtcagctcta
    11341 tgagcatcgt acaaactggg tcaagaccaa caattatgac gctgtttatg acaccattca
    11401 gcaatgcatc accaaaggct atcaaagctt tatcatggtt actggcaatc ctaatttgct
    11461 gagcacacgc atcgagcgtg cctctggttt tattgatgtt ttagaggcta accagctcca
    11521 gtatcgtcaa atgatcatcg atgaaaacca aaccagctct caagaaattg ctcagtttct
    11581 acaaggcgca tttgataagg aacgtcacaa tctggtattt gtcccaaact gctgggctct
    11641 gcctaaggtt tttactgcca tgaaggcact aaaggtatca ttgcccgaaa ctggtctagt
    11701 tggctttgat aacatcgaat ggactcgctt gtcatcacca agtattacca ctattatcca
    11761 gcctgcttac gaagaagggg agcaagcaac cagcattttg attgatgata tcgaagggca
    11821 tagcaaggaa gccaagcaac aaatttttga ttgtcaggtt aattggcaag aatcaacctt
    11881 ctaacaggat tttttcgcct tctagacctt aaaaaatcag ccattctaat aacgatgaca
    11941 aagtaacacg aggcttaacg cttgtttgct agcatcagaa aaaacacata aatcagcctg
    12001 aactacccgg ttgatgaaac aataaaccat taagcaacgg tcttattcct cataccaaga
    12061 ggagcaaggc cgttttgacg tttttgacaa tggtcgttat tgtaaacgta acggtagtgt
    12121 attactgaca ggctcttcaa aaaagctgtc gtccttaggt catacgaggc cttcttttac
    12181 aagcgactgc tacttcttca ctactagtgt gatcttttag ccaatttctg agaacatcat
    12241 cagtaaaatc tcgcacctgc caataatggc aagcaagctt ttttgaccag caagttaatc
    12301 atgtatcact tgtgacttca actcttaact gtttgtcctt tcaagtctac tataagag
//
LOCUS       DARYVE010000057        12350 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYVE010000057 DARYVE010000000
VERSION     DARYVE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12350
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(171..980)
                     /locus_tag="TVW25_001573"
     CDS             complement(171..980)
                     /locus_tag="TVW25_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1379190.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(973..1815)
                     /locus_tag="TVW25_001574"
     CDS             complement(973..1815)
                     /locus_tag="TVW25_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1379191.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(1791..2630)
                     /locus_tag="TVW25_001575"
     CDS             complement(1791..2630)
                     /locus_tag="TVW25_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1379192.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(2633..3175)
                     /gene="pgsA"
                     /locus_tag="TVW25_001576"
     CDS             complement(2633..3175)
                     /gene="pgsA"
                     /locus_tag="TVW25_001576"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1379193.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(3188..4192)
                     /locus_tag="TVW25_001577"
     CDS             complement(3188..4192)
                     /locus_tag="TVW25_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1379194.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(4242..5525)
                     /locus_tag="TVW25_001578"
     CDS             complement(4242..5525)
                     /locus_tag="TVW25_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1379195.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(5527..6771)
                     /locus_tag="TVW25_001579"
     CDS             complement(5527..6771)
                     /locus_tag="TVW25_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1379196.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            6986..7399
                     /gene="yaaA"
                     /locus_tag="TVW25_001580"
     CDS             6986..7399
                     /gene="yaaA"
                     /locus_tag="TVW25_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1379197.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            7401..8510
                     /gene="recF"
                     /locus_tag="TVW25_001581"
     CDS             7401..8510
                     /gene="recF"
                     /locus_tag="TVW25_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1379198.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(8575..9438)
                     /locus_tag="TVW25_001582"
     CDS             complement(8575..9438)
                     /locus_tag="TVW25_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1379199.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(9609..12038)
                     /locus_tag="TVW25_001583"
     CDS             complement(9609..12038)
                     /locus_tag="TVW25_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1379200.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
BASE COUNT         3812 a         2645 c         2307 g         3586 t
ORIGIN      
        1 caatattgat attccaagtt ttctagcctg atatcagtgt tttttgagct taagaagctc
       61 aaaataaaaa caatgcctaa gttcagacct gtgtaacaga tgatttaagc attgttatta
      121 ttaataaatt ctagttgcta cagcctaaca aaggggctgc tgtaatatag ctaggtgagc
      181 cttgagggac tttttagaca gaaaaggaaa atccccaaaa tgactaccaa aataatggct
      241 agagtgtctt ttaattgcca gcttagcagg cggtattttg ttcgactgtc accgccttga
      301 tagcctctag cctccatagc gatcgctaaa gcgtcagctc ttttaaagct tgaagcaaaa
      361 agaggaatca aaatagggat aatcgacttt accttttgaa taagattgcc ttctccaaaa
      421 tcaacacctc gcgctttttg cgcattcata atacgagttg tatcgtccat caaggttgga
      481 acaaaccgta agctcaaaga taacatcaaa ccgatctcat gggcaggtac cttaaaccta
      541 actaaaggct tcaacagcgc ttcaacagca tcagataagc ttagtggggt ggtggttagg
      601 gttaacagcg tggaaaagaa aataatcaaa acaaatcgca tgaaaatcaa aatggcttga
      661 cttaatccca agcttgttat cttaattatt ccaagctgaa aaagaactga tcctccctgt
      721 gtaaaaaaaa cttgaaaaag cgttgtaaat aggataatac caatcatagg cttaacacca
      781 ttgaaaaaga aagaccattt tatctgtgac aagaaaatca gcagcaaggt aaatgctaac
      841 agcaaaagat tagttaccac attattggcc caaaaaataa tgataatata gataatcata
      901 gcaagcagct tgcttcttgg atcaagccga tgaataattg aattcccagg aatatagcga
      961 ccaagaatga gtttatccat gctttaatac ctctcttaat tcctccaaag taatgggtaa
     1021 atagggtaaa tcaaagcctt gcttagccag gcgttgggca aaggctgtca ccttagggac
     1081 acctaattgt ttttctttta gcaaatcaat gtgttgaaaa atagcctttg gctgacctga
     1141 taagatgatt ttaccagctt caaggacata aacaaaatca gcataattag caacatcgtc
     1201 catcagatgt gtcaccagta caatggtcat gcctgattga tggagcgatt taaaaagact
     1261 cattaattcc tttcgccctt tgggatcaag cccagcagta ggctcatcta acaccaaaat
     1321 atccggctgc atcgcaagaa tacccgcaat agcaaccctg cgcatctgcc caccagaaag
     1381 ctcaaatgga tttttaccaa atagttcctc tgaaatccct actagggtta atttttcacg
     1441 cgctaaagct tccgcctctt tctgagaaac accaaaattt tgtggtccaa aggcaacatc
     1501 cttcaaaacc gtttcctcaa aaagctggct ctcaggaaat tgaaagacta gaccaacctg
     1561 cttacgaata ggcttaatat ctttattttt tgactgacta gttatctcct tgcctgctac
     1621 cgtaaccttg ccggtggtcg gcagatgcaa gccatttaag agctgcataa tcgttgactt
     1681 gcctgagcca gtatgaccaa taaaagccgt ataagagccg tctacaatat caagattaac
     1741 gtcaaaaagg gcacgcccct caaagggtgt ccctgcttga tacgtgtagc ttacattttg
     1801 gaaatgaatt gacatagctg ttcctctaat tccttttctg tgagatagat tccctgtata
     1861 gggtagccgt ctttttttag catattaaca acagaggttg taaaaggaat atctaaacct
     1921 agattgatca attgattgcc cctagcaaat agctcctgtg gagtcgagac agactcaaca
     1981 cgcccattgt tcatcaccaa agctcgatca ctaagagcca cctcatcaag atcatgtgta
     2041 atagatataa cagttagttg gtattcttgt ctaatagatt gaattgtccg aatcaactcc
     2101 agacgcccct ttggatccag catactggtt gcttcatcta aaatgatgat cattggccgc
     2161 atggcaacag cacctgcaat agcaacccgc tgcttttgac cacctgataa tctggaaggc
     2221 tccttatcct taaaagcctc cataccgacc agctgcaacg cctgatgaac acgctctatc
     2281 atctcctgat gggaaacacc tttgttttca agaccaaaag caacgtcatc ttcgacagtt
     2341 gcaccaacaa attggttatc aggattttga aataccatgc caattttatg acgaatgtcc
     2401 cagacattgt cctctgtaag aagatcacca tcaacaaaaa tctggccggc ttctgctttc
     2461 aatagcccat caattaacct aacaacggtt gacttgcctg agccattatg cccaatgata
     2521 gacaaccact cgccttgttt cacatgaaac gtcacatcat ctagggtata tcgctcctgg
     2581 tcctgcttat acttaaatgt aagattctta acttcaataa tatttgacat tgttatttaa
     2641 aggtatcctt aaaaagaaag cttgctcctt tgaaataatc gtaacctgaa taaatcgtaa
     2701 acaatagagc aatatacagc aaaacagtgc ctaaaacagt ccaatgacac agtaaaaaga
     2761 tgatggaaag catctgtgct actgttttga tcttaccagg catagcagct gctaggacct
     2821 tatctccagt ctcaaccaat agcaaacgaa gtcctgtaac agctagctca cgacagataa
     2881 taaccgctga cacccaagcc ggtaccagct ctaagcccac taacataata aaagcactca
     2941 tgacaagcat cttgtctgcc aatggatcag caaatttacc aaaattagta acaacctgcc
     3001 acttacgtgc aaggtaacca tctaaataat cggtcaggct tgccactgca aaaataatcg
     3061 ctgcaaaggt atgccaaccg actgtctttg aaaaagaggt gatcaacaaa aacaatggaa
     3121 tcatgacgat acgggcgaga gttaacaaat tgggaatatt ttcttttttg atcatgctta
     3181 taccttatta ttgtatcttc agtgtgatat agctgatatc agtacttgtc attgctgata
     3241 aatctagggg ctgaccatca attgctactg aaacaccctt tgttacgcct agtgtcaaca
     3301 aggattctgt tgtctcagca ggcaaggtag tagaataagt cggattgtcc tttgttaggg
     3361 tcataccagc ctcaccaatt tccgaattag tgagggaaat ccaactgctc tcagcatcag
     3421 tcagtgacac tgtaacatca acagcttctt ttgatttagt aatattagca atcaagtaat
     3481 tctctgcgcc ctctgttgtg atcaccgtct taggctcaga tgagctggac gctgttgagt
     3541 gactgctttg tgatgactta agaaaagaca tctcagcctc ttttgctttt tgacctttat
     3601 caaattgctt ccaaacagca aaaccaataa caccaacaat agccacagca ataagaccta
     3661 gtaaggctga tggaaaggct gattttttcg ttttagcact atttccataa cgacttagcc
     3721 ttgaagcact ggtctctcta gtccgtctat ggtcagtagc cttaaagtga ctagctgtag
     3781 gagctgattt gcttgaggat agtgacgtct tgacaggaat cactagggtt tctggttgag
     3841 tccttgaagg ctctggttga gctatttttt cagaatagct attctcttgt agcctttttt
     3901 tgctgagctt ttcttcaacg atttgtgtga ctgatggtgt acctgtttcc tttttaaagc
     3961 tcacctgcag ctgatacaag cgttttaagc tatcaaagtc taagccaaca atatcagcat
     4021 attgctttag aaaatgacca aacttttctt ctggaatgat tttgaactgg tcaagctcca
     4081 ttgccaatag ataatgcgag gaaatgccag ttttagcttc aatttcgtct aatgttatgt
     4141 tttttccgac acgtgtttct cttaataatt caccgagact tgtttctctc atacgagtac
     4201 ctcaaaaata ttgtaataag accattataa cagattttaa gctatttggg aaagactgta
     4261 aaatctgaag tagctgcatg ctcaaaaaac aagcttccta tttcgataat atcctttaaa
     4321 gctagggtct caataatcct aggaatatca aaataggtct cttgctctga taaatgaagg
     4381 ctaaattggc ttgccagctg atcaatagcg tctaagcttt gcataaaatc cccatacatt
     4441 tcctttttca ctagctctaa gtgctcctca ttaacgtctc ttgagcatct aaaatcggaa
     4501 atcttttttc taatgctgtt agacattgca ataggctgac tagtatctga agaaatcaat
     4561 acaaattgga aatccctttg aatgtcaacc tctatatcaa aggagtcgtc tatcttgccc
     4621 ttttcatacc aatcctgata ggtttttgac gtccagccaa ggagcaccgc taggagcagt
     4681 ctaagagcta cctgataggt gagtagagaa tactcgcttg acattagctg accgcgaaag
     4741 ccgactgcta atttggcagt cgcaacgtcc atatcaatag atctagactt gatcacaggg
     4801 tagtaggtca atggagctat ctgtacatca tactgcgtct gacttggttg actatcttga
     4861 aaggcttcaa tagctgtaaa ggcttcttca atgtcaatat cgccaataat cgttaagacc
     4921 atgttagaag ggtgataaaa ataagcatgg ctgtcagcca ataaagagcc tgtaatgtcc
     4981 ctgatagact ccttggtccc agcaatatca acagctaagc tggtattggg aaagaggttc
     5041 tgtaagatac cactgtaagc ctgataatca ggatcgtcct gatacatctc aatttcttga
     5101 gtgataatat gtttttcacg attaaccgac tcctctgtaa agctaggagc tgctacaaat
     5161 tcctgcaaaa gtctcagact ttcttgccat tcattgacag ttgaaaagaa atagctcgtt
     5221 ttatcaaagg ttgtaaaggc atttgtttct gatcctaact gtgtaaatgt aagagcaata
     5281 tcattaccat ctttatcctc aaatagcttg tgctctaaga aatgagcaac acctgacggc
     5341 aagtcaaacc tttgacaatt gactgtaaag cttgtgtcaa gagaaccaaa acgagcagtc
     5401 agcatagctg ttttctcaga atagccctct ttctttatca aataaaccct taaaccattt
     5461 gccaattgac cgtagtgtaa ggtctcttta atgctgggat agtctttttt cagtagtgac
     5521 gtcatcttat tttccctcta aaaaatatac agcttgcagc ttgagtagat tagctgtcct
     5581 gacaatatct agcttgctaa ccttgtcaat ctcgtcaagc caacttgaca aagtatagga
     5641 aggatctata taagatctca tgtattccag ctcaatcaag gctttactat tatcctcaga
     5701 tagcaaggcg ttatttttta gcattagctt tgttttcttg acaaggctgc ttgaaaagcg
     5761 ccccatcttg atgtcattga gctctttaac cattagctgc agggctcttg tccggtgctg
     5821 tctatctatg ccagcataag cctcaaataa gcctgtgtaa acatcaaatc gactaccaat
     5881 actataggcc agcccctcct tctcacgaat ttgggtaaag aagcgagagt gtgtaaaggc
     5941 tcctaataga ccatttaaca caactaaggc ataatactct gcttgcccat aaaccagcgg
     6001 aaaatgatag gctagctcta aaacagactg attaagctgc ttttgctcga ccaattcgtt
     6061 gacaacattg acaggctgct gtaaataaaa gaaatctagc tttttcctgc gtccctcaaa
     6121 gggaaattgg tgtaacaatt gtaccatacg ataatcatca aaatcaccaa gaataaaaat
     6181 atcaatctga tcctcattca acattttatg aaattcttga tagcttgtgt aggctgtttc
     6241 tttagcaatt aactcagtat taccatattt tgacagcttc aggctatcat tagcataaaa
     6301 taattgcttg gcttttaggg cactataata aaaggaatcc tccttatctg cctcgacata
     6361 ggtcatcaaa tgtctttttt cgatgtcaaa tagtttgggc tggtactgag ccactgataa
     6421 caaaggagaa aaaaggatat cctttagaaa ttgaatcatt tcgtctagaa gcttctctcc
     6481 ataaaaagca tactgatcct gaataaaggt aatgtcaata tccacaatat gaaccaaacc
     6541 cttggttgac acatgagttg acaggcttgc tccatacatt tgtgctaatt tttctctaaa
     6601 ttgcttggca gtaggatagg tatcgttagc cgttgctaac atttgagcta ctaagactcg
     6661 ctttgctacc gttttttgat tcaaatcacc tgaaaagcga aacgttatct gattcgtttt
     6721 aaatgttttg ttttttatca gatgaagctg aactccctga ataagtttca taatatttcc
     6781 ttattaataa atgtgtgatc tctagaatta taccattttt atcgctattc gttgagtgtt
     6841 aacatcagtc tggtagccta ttttgactct ttatcaaaat gctatcctgt ggctatagtc
     6901 tagactttag aaggtcagca tttcagcatt attatttagt ggctttttat gctataatga
     6961 cttgaatgac aaattggaga tgactatgac atacacacta tttactgact ttattaccct
     7021 acaagcttta ttaaaggagc aaggtattat ccaaagtggt ggtgccatta aaggtttttt
     7081 agctcaaaca gaggtttttt taaatggtca agaggaacaa cgacgtggca agaagctaag
     7141 agtcggtgac gtcatcacca ttccatcaca gcacatcaag attgagcttg tagcgcctag
     7201 tcaggccgaa aaaacagcct atgaagctga aaaggcagaa aaagagcgag ttgctaagat
     7261 ggttaaacaa atgaatcaac aggctaaaaa agcacagacc aagcaagcag ctactaccaa
     7321 aagcaagcgt ggtcaagcta cctcagctgt aaaagctaag tctaatcacc aaaagcctat
     7381 tcgcttccca ggattgtagc atgtggatca aagaactaaa cctcacccat taccgtaatt
     7441 atcaacaagc ctcagcagcc ttttcaccgg gcttgaatgt tttcattggt gacaatgcgc
     7501 agggcaagac aaattttctt gaagctattt attttttgtc agtaacaaga agtcatcgca
     7561 ccaaatctga taaggactta atctactttg acgaaaggga ttgctctata tctggaactc
     7621 ttgagcgcct tagtggtcgt gttcagctag aaatactgct gtctgataag ggacggatca
     7681 ccaagattaa caccctaaag caagcaaagc tttctgatta tatcggagca atgatggtgg
     7741 tcctctttgc tcctgaggat ctacagctgg tcaaaggctc tcctaatctt agacgaaaat
     7801 ttatggacat tgacttaggt cagataaagc ctgtttactt atcagatttg tcacattaca
     7861 atcatgtcct aaagcagcga aatgcctatc tcaaaagtgt tcatcagctt gataatgact
     7921 ttttatctgt gttagatgag cagctggtta cctacgggag tcgtgtaatg gcgcatcggt
     7981 tggcgtttgt tcaatcacta gcaaaagagg caaacaagca tcatcaagct atctctaatg
     8041 gcctagagaa gctttcgatc tcctatcaag cctctgtgag ctttgagcac cagcaagaga
     8101 tttatcagca attcatgaac cagctcaaaa ccactcatca aagagatttc ttgagaaaaa
     8161 atactggtgt tggcccccac cgcgatgatc tggtttttta tattaatgac atgaacgcta
     8221 attttgctag tcaaggccag catcgtagcc tgattttatc actgaaaatg gcagaggtta
     8281 gtctgatgaa gcaattaaca ggtgacaacc ctattcttct acttgatgat gttatgagtg
     8341 agttagacaa taccagacaa acaaagcttc tgggagctgt caagaaagaa aatgttcaaa
     8401 cctttatcac aacaactagc ttagagcatt tgtctcagct acctaaggac attagtctct
     8461 ttaaggttaa taaaggaaca atagaacgag attctatcat gattgattaa ctgagcaaac
     8521 taaaaaaagg gcaccttaat agtgaccctt tttacggtta aattagttga tactctatga
     8581 tttgacgata cctaagagga tagcgccaac aataaagcaa aggatacctg taatgaccca
     8641 gcgcatctct tttttggttt ttgtctcacc taagaataaa atacctccga caatagagat
     8701 aatagcgccc aattgtgaaa agctaaaagc aatcgccaga ccagcctttg aggctgctag
     8761 cagcatgaag atatttccaa ctccccaaag caagccaaca acactatttt tgataacata
     8821 ctggtcaaac gataccttaa acgacataaa catggctgca ccaagcacca ttcccactgc
     8881 catcggtaaa ataaccgaca acacatcaaa tttcataatg ttattgaaca gcacagcata
     8941 catcacatag ccggttgtcg agtaggttaa ggctctaaag ccctttgaaa aatcatgcaa
     9001 ttgattactt gctgcattcg tctcgtcctg cttgcttgaa aaataaaaac caacaatcaa
     9061 aagaagtaag gcaatcgtac caacgacaaa ttgaataggc ttggtccact catgaaagac
     9121 cagcacacca atcaggctac ctaaaactag ctgagaacca ctagacaagg gatttgctac
     9181 tgaaacaccc atatactgca tggcatgaaa ttgcccagtc tgaccaacag accagataat
     9241 accacctaaa atcccaaaaa tccagagctt catagacatc tcaggtctga ctactaacca
     9301 aacaactaga gcaaatagta aagctcctat ggtcattcca aaggtctgct gtgagggttt
     9361 accgccaatt ttattactaa caaagccaat acttccccat gcaaacattg ggacaagtgc
     9421 aaataaaata ccttccaaat ttacatctcc tttacaataa gttgacacat gatgttaacg
     9481 ataaaagtgc tttcatacgg agaattatta tagcctattt ccttagaaaa tacaataaca
     9541 tgatgtaaaa aatcatctgc tcacacgctt ctccctaaaa aggtgtcaaa gtagctgaca
     9601 gagcttattt actgcaatgc tagaggatta tttaatgaaa accgtttgac cttatggctg
     9661 gctctagctg gagctttgtt agggactttt gtgacctgag ttccaaagca atcagcaact
     9721 agctgactga aatagcctaa gcgtttgagg agtagagcaa gatgattaac catagcacta
     9781 gctgcttgac cggacatgct tgcttctatg gtagctttga caaaggatag ctcaacgatg
     9841 attttatcca gcagtctgcc aaccatcttt tgactagtga tgatgtcatc taaatcaaga
     9901 gcgctgtaaa ctcctttttc gatcaatcga ctgagatctc catgcaagtt ttgaagccga
     9961 tgccttgcgg tattgactcg ctgtatcgta tcagtcaatg ccggtactag aggacatacc
    10021 tcagctctgg cagaagcaat accggatctt atgcggcaag gatataaagc acccagattt
    10081 ccccaatagc tccttgtcgt tgtagaggtt tcatctttga tttctgttcg ttcaacataa
    10141 accctatctg aaaaacgtct ctctaatact gtcacgatat tcttaaagat attcacctca
    10201 gtagtccaat aatcaagtgt atcaaatagc cttgaaaagg ttgacgcata aacagaggca
    10261 acctttctgg aatagtcccg actcttttgt tccacctgct catcaaaggc ttggagaata
    10321 tctctgacat catctaaaag acctgttctt tctaggtaag catcatagct gcttgggaca
    10381 cagacgacat cagcacttcc ttgaaattga ccatttttta ggctgttgcc tagccagtta
    10441 tctgtagctg tgacattttg tgatacccct aggatcagct cactggtatt gattatcatt
    10501 ttttccagct ctatgatatc ctgtaattcc acgctaaata cctcttttaa ggaatcgcta
    10561 ataccgtcaa ctttactttc acgtaaaccc gttccttcaa aggtcttatc actctccttc
    10621 aatagctgac gactggcctc atcaataatc tgccaagatt tcaaaagtgt cgagcgaccg
    10681 ataatactat caatccagcc tgacttttca tgctgagcag atgaggcaag ctgaagcgat
    10741 tttgtgttta agctcgctaa ttctgaatca tacatggcca gattgaggcg attattattc
    10801 acatatggga tctcatcata ggaaaaggga tagtctaggc tagccgaatg agacagcata
    10861 tcaaacaagt cctgctgacc aactaatctc tccaaagaac tttgcaggct attaaaagta
    10921 tcggttaggc catttgtagc aagcagggct ttgatgtttt ctgaaactcg ctttttcctc
    10981 tcttcaaagg agtcttttat ggcatcattt tttgcctgac atttttcagt aatgtggcga
    11041 atcgtttgca ggtcgcctga tatagaggat tgaaggtttt gtgcaaggtt agtcaggaca
    11101 ccagcattga tgacaatcgt ttgcttatca gaaagcacac cgtaccgagc cgatgttgac
    11161 gaatcaaagt aatttctaaa gcctaagtac agctcctcta ccttagtgtc taatcggtta
    11221 tcgctgtcaa tatcaatagg caacaggaca ttagcatgaa caaaccggcc atttacgtct
    11281 gtcatgttgc catattgatc atactgatag ccatgccaca tatgctgtaa gactatatca
    11341 ttgacctttt ttgtattgac aacaaagacc tgaccgactg ctccctcctt ttggtcaaag
    11401 cccataccaa tgatgtcatg cggatccaca tagttgtaaa tgcggtcatg caagagcttt
    11461 gcacgttttc tttgatactc attaagcaca cgataggtgt tggggccatt gtagatatag
    11521 actccagaga tacgagataa gtttttatca ctaacagagg taacaccgta ctgaactgtc
    11581 atggagccta gcgaatgacc ataaaactca aatgttgcgt tagggtattg ctttaatgtc
    11641 ttattggtaa aggttgctgc ctttcggagc tgagctgtcc ctttagttgg tgtctggtcc
    11701 ggtaaaagaa tgcgcatagc cataggcaaa tcattgccta cccaatctgc aaccacatct
    11761 actgggtgtt tctgccactg gtctgggcca gtagagcccc ggtacagcat ggtgacatgc
    11821 ttgacctgag catagtctgc cttggtagga tgagggggaa gcttgacatc tgtcacgaca
    11881 taggcttgaa aacctgatat cgaatcctct atctgagaca cataaccgat ggaaaactca
    11941 gaattatcat catcaattaa aactggtgaa cctactgtat gtttttcata ctcttcctca
    12001 gcaatccgtt gtctctgttc gtctgtcagg atcatcattt tcactctcct tttagtagtt
    12061 tttctaactt ttctgagcga taattactag cgatctctaa atttctttct aaatcatatc
    12121 tactaaggcg aacccttaaa taagtatctg gatcatcatt gataatcagg tgaatagaaa
    12181 aacctcccct ggcttgaatg aactgtgaac tgccccccaa aagttagaca taaaatctaa
    12241 caattggggg gctattttta tgacattgag ttatgaagac aaggttcaaa tctatgagct
    12301 acggcacatt ggaaagtcca ttaaatgctt atcagaaaag tttagtattg
//
LOCUS       DARYVE010000058        12296 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYVE010000058 DARYVE010000000
VERSION     DARYVE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12296
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(262..465)
                     /locus_tag="TVW25_001584"
     CDS             complement(262..465)
                     /locus_tag="TVW25_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1379201.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TVW25_001585"
     CDS             complement(482..736)
                     /locus_tag="TVW25_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1379202.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TVW25_001586"
     CDS             complement(1478..1774)
                     /locus_tag="TVW25_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1379203.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TVW25_001587"
     CDS             complement(1781..2029)
                     /locus_tag="TVW25_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1379204.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TVW25_001588"
     CDS             2289..4445
                     /locus_tag="TVW25_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1379205.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TVW25_001589"
     CDS             4456..5814
                     /locus_tag="TVW25_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1379206.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TVW25_001590"
     CDS             5914..6045
                     /locus_tag="TVW25_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1379207.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TVW25_001591"
     CDS             complement(6167..7501)
                     /locus_tag="TVW25_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1379208.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TVW25_001592"
     CDS             complement(7501..8250)
                     /locus_tag="TVW25_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1379209.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8877..9080)
                     /locus_tag="TVW25_001593"
     CDS             complement(8877..9080)
                     /locus_tag="TVW25_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1379210.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(9097..9354)
                     /locus_tag="TVW25_001594"
     CDS             complement(9097..9354)
                     /locus_tag="TVW25_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1379211.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TVW25_001595"
     CDS             complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TVW25_001595"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1379212.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(11039..12007)
                     /locus_tag="TVW25_001596"
     CDS             complement(11039..12007)
                     /locus_tag="TVW25_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1379213.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            complement(12147..>12296)
                     /locus_tag="TVW25_001597"
     CDS             complement(12147..>12296)
                     /locus_tag="TVW25_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1379214.1"
                     /translation="DCDYITGDTVMIVRKNGRIFDYVLPNEEIRDWEVVIEERVEEVM
                     RELDK"
BASE COUNT         4008 a         2785 c         1892 g         3611 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaaat aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctaaca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag
     8641 atgaacaatt tgttacactt gatttgatca tcggggttta gaaaaaatag tgaaaagaat
     8701 cctcataatt cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta
     8761 taagaagtag catgattaaa gttatagaaa ttcttatcaa cgcttcttct tttttaacaa
     8821 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
     8881 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
     8941 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
     9001 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
     9061 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
     9121 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
     9181 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
     9241 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
     9301 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
     9361 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
     9421 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
     9481 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
     9541 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
     9601 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
     9661 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
     9721 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
     9781 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     9841 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     9901 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     9961 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
    10021 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
    10081 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
    10141 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
    10201 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
    10261 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
    10321 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
    10381 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
    10441 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
    10501 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
    10561 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
    10621 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
    10681 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
    10741 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
    10801 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
    10861 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
    10921 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
    10981 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
    11041 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
    11101 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
    11161 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
    11221 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
    11281 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
    11341 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
    11401 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
    11461 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
    11521 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
    11581 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
    11641 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
    11701 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
    11761 caagccaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
    11821 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
    11881 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
    11941 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
    12001 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
    12061 taatgagggt atagataaaa ctcctaaaat tgtggcttta caatgtcgtt ccccgacaat
    12121 tccccgactt ctggacgagg tcttttttat ttgtctaatt ctctcatcac ctcttccact
    12181 ctttcctcta tcacaacctc ccaatctctt atctcctcat tcggcaacac ataatcaaaa
    12241 atccgtccgt ttttgcgcac aatcataact gtgtctcctg tgatatagtc acagtc
//
LOCUS       DARYVE010000059        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYVE010000059 DARYVE010000000
VERSION     DARYVE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(152..433)
                     /locus_tag="TVW25_001598"
     CDS             complement(152..433)
                     /locus_tag="TVW25_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1379215.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TVW25_001599"
     CDS             complement(466..1233)
                     /locus_tag="TVW25_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1379216.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TVW25_001600"
     CDS             1352..2092
                     /locus_tag="TVW25_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1379217.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TVW25_001601"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TVW25_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TVW25_001602"
     CDS             3072..5315
                     /locus_tag="TVW25_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1379218.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TVW25_001603"
     CDS             5428..6489
                     /locus_tag="TVW25_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1379219.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TVW25_001604"
     CDS             6567..7172
                     /locus_tag="TVW25_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1379220.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TVW25_001605"
     CDS             complement(7423..8637)
                     /locus_tag="TVW25_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1379221.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVW25_001606"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVW25_001606"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1379222.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TVW25_001607"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TVW25_001607"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1379223.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     GNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TVW25_001608"
     CDS             10819..11535
                     /locus_tag="TVW25_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1379224.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TVW25_001609"
     CDS             11627..>12157
                     /locus_tag="TVW25_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1379225.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3303 a         2348 c         2832 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacggta atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYVE010000060        11883 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYVE010000060 DARYVE010000000
VERSION     DARYVE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11883
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..397
                     /locus_tag="TVW25_001610"
     CDS             <1..397
                     /locus_tag="TVW25_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379226.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TVW25_001611"
     CDS             441..1106
                     /locus_tag="TVW25_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1379227.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDCIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TVW25_001612"
     CDS             1103..2080
                     /locus_tag="TVW25_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1379228.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TVW25_001613"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TVW25_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1379229.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TVW25_001614"
     CDS             complement(3407..3844)
                     /locus_tag="TVW25_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1379230.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            4045..4737
                     /locus_tag="TVW25_001615"
     CDS             4045..4737
                     /locus_tag="TVW25_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1379231.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(5113..5589)
                     /locus_tag="TVW25_001616"
                     /pseudo
     CDS             complement(5113..5589)
                     /locus_tag="TVW25_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TVW25_001617"
     CDS             complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TVW25_001617"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1379232.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7651..8349
                     /locus_tag="TVW25_001618"
     CDS             7651..8349
                     /locus_tag="TVW25_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1379233.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            8561..8893
                     /locus_tag="TVW25_001619"
     CDS             8561..8893
                     /locus_tag="TVW25_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1379234.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8908..10479
                     /gene="ffh"
                     /locus_tag="TVW25_001620"
     CDS             8908..10479
                     /gene="ffh"
                     /locus_tag="TVW25_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1379235.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(10632..11855)
                     /locus_tag="TVW25_001621"
     CDS             complement(10632..11855)
                     /locus_tag="TVW25_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1379236.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
BASE COUNT         3749 a         2259 c         2211 g         3664 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgactgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tataacatgt ttggcattaa acctaagaca gcttactgtc ttttcgatat aaacataaaa
     3961 agcttgaata ttcttataag ctatgttata ctctggtaaa gttaatactt tactagagta
     4021 tactgacaaa ggagatttat gctgatgttt tctggtattc aattaaaaac agcacgttta
     4081 tcaaggcata ttagccaaga acagctagga cagcttttag gagttaataa aatgactatt
     4141 tccaattggg aaaaggagaa aaatagacca aatcaaaagc attttgaaga gcttgtgagc
     4201 atttttcaat tacctgctga gtacttttat caagaaaatc gtcttttact tccctatagt
     4261 cagttaagcg cctctaataa agaaaaagtt atcagctatt ctgagagctt acttgaacaa
     4321 aaagaaaaaa taattgcttt accagctaag aaaaagacac tttaccctta tcgtgtttat
     4381 gaaaggttgt ctgcagggac tggctattct tactttggtg atggtaattt tgatgttgtc
     4441 ttttacgatg agcagttaga ttatgatttt gcttcatggg tttttggtga ctccatggag
     4501 ccaacctatt tgaatggcga ggttgttctc atcaaacagg atagctttga ttatgacggt
     4561 gctatctatg ctgttgagtg ggaagaacaa acctatatca aaaaagtata tcgtgaagaa
     4621 aatggtctgc gtttggtttc attgaacaaa aaataccctg ataaattcgc ttcctttgat
     4681 gacaatccgc gtattattgg aaaaatcatt gccaacttta tgcccttaga tgtataagcc
     4741 tttgtattag cttaaaagca tgactgttgt acaaccaaac tcattgcatg acattggtgc
     4801 attatttttg aagtggcttc tacttctttg atttactttt ctgcattaaa aagcccatta
     4861 aaggtttttg aaacttatta cttagacaaa ggctctatta aaaatcataa ccaaccggtg
     4921 gtggtttatt tgtcatgtac cttgcatttt gtgacagact tcataaaacg aacaaaacac
     4981 atcgctaaaa gattttacca tcttaaagtt atgtgttttt tgtataaaaa cttatctata
     5041 tgcttgatta accaactgag ataaatagat tattatttca tagagaagtt tgttatctaa
     5101 tccaaataat cgtattatcc tcttaagttc ctcaacatta taaccatcac aatctgttgg
     5161 cagtttattt ttttcaagcc acttatcaac cactgctatt cccaaagaaa ttgaaaaatc
     5221 tttttcttta tcaaacttac acaattccac tgccaaagtc aatacaaaat tcctgtgaat
     5281 attatcgtaa ttttcatcaa ataattgcct ttccaaaccc acaatagata gccgactaaa
     5341 tatgtatctc cctatttctt cgtcaatacc ttcagtagcc ttaatagctt cttggacaac
     5401 attattccag aaagcatttt tattacgctc ttctataaaa gttttaagtt tcattttgaa
     5461 aatatcagta atttgaccaa ctgctttatc aataacctat gaaacaatat tcttcatcat
     5521 tatgattttc tcctcgtata cataaataat tgtatctttg ctatataatt gtggtatctc
     5581 ttcaatcaac caatattgtt cttaaactat tccctcaaaa gccttccacc aaaacgatgg
     5641 aaggctttta aaccattcac ctaaattcaa caactccctt ttgaacttgc tattttagct
     5701 ttttagtatc aaagcagtat cactcaagag ttttttgttt ccacaaaccg caaaaaccca
     5761 ctgttttcaa cactttcatg gcagtaatat atttgcttct gtcactccca ctcaacggtt
     5821 gctggtggtt tgctggtgat gtcgtagaca atgcgattaa cgtggtcgac ttcattgaca
     5881 attcgaactg agattttctt tagaacttcc caaggcaatt gggcaaagtc tgctgtcata
     5941 ccatcaattg aggtgatagc acgaatagcg atggtatagt cataggtgcg accatctccc
     6001 ataactccga cggaacgaac acctgtgtta actgtaaaat attgccacac atcacgctca
     6061 agtcctgctt tagcaatttc ttctcgaagg atagcatctg actcgcgaac tgtttcaagc
     6121 ttttctgctg tgatctctcc catgacgcga atggcaaggc ctgggcctgg gaaaggctga
     6181 cgccagacga cttcatctgg cataccaagg gccgtaccaa gagcacgaac ctcatcctta
     6241 aagagtgtat tgaggggttc gattaattca aactgcatat cctctggcag accaccaaca
     6301 ttgtggtgag attttatcgt ttgagcagtt tctgttccag attcaatgat gtctgtgtaa
     6361 agcgttcctt gtgcaaggaa gtcaacgccc ttaagcttgc tagcctcgtc atcaaagacg
     6421 taaacaaact cattaccgat aattttacgt tttttctcag gatcctcaac gcctgcaaga
     6481 agatctaaaa agcgctttga ggcatcaaca cgaataatat tgagaccaaa tcttccacca
     6541 agcatttcca taacttggtc accttcattt ttacgaagaa gtccatggtc aacaaagata
     6601 caggttaatt gatctccgat agctttttgt aaaaggacac caacaactga agaatcaaca
     6661 ccaccagaca aacctagcaa aaccttacga tctccgactg tttcgcgaat tttagcaatt
     6721 tgcatgtcaa taaaattatc cattgaccaa tcaccacgtc caccacagat agagatagca
     6781 aagttcttca aaatatcatt accatagaca gagtgtctta cctctgggtg gaattggata
     6841 ccgtagagcc tcttttttgt attttccata gcagcgtaag ggcaatcgtt agaatctcct
     6901 acaagatgaa agccctctgg gatttctgta acagcatcac catgactcat caaaacaagc
     6961 tgctcatctg gagtgcccgc aaataatgct gatgcagaac gtaaacgtaa tgatgattga
     7021 ccatattctc ggtgacctgc ttgaccagct gggactacct tacctcctaa ggtatgtgtg
     7081 attagctgca tgccatagca aatccctaaa attggaatcc ctaattcaaa gatttcagga
     7141 tcaataccaa aggcatcagt tgcataaaca gaatttggcc caccagacag gacaatcccg
     7201 attggattga tgtcacgaag ctcttgcgca gtgatgtgat ggcttttgag ctcagaaaaa
     7261 acaccaaact cccgaatacg tcttgcaatc agttgattgt actgactacc ataatcaaga
     7321 acgataattt tttgaatatc attcaacatt gaaatttcag tcattataac cctttcatta
     7381 tataccagaa ccttgttagc tgatagtttt caattaattg tagcatattt tcactaaaaa
     7441 ggcattagct tttcaggtga tgtgatgaaa aaataagctt tttgcagaga tattaaaatg
     7501 aatgacctca actatcttat gtatgactac tattgtcagt cttagcatga aaaagctgat
     7561 tgatgatgag tgtttttggt aataattggg ctgctattta ggctgaaaat atgataaaat
     7621 aaaaccatca tcaccctcaa ggagtaaagc atgctgccag cttatataaa aattcatgac
     7681 gctattaaaa aagacatcga aaaagaagtt tggactattg gtagtcgcct gccaagcgaa
     7741 cgagatttag cagaacattt tgaggtcagt cgcatgacgt tgcgtcaggc aataacactg
     7801 cttgtagagg agggaattct agaaaggcgt gttggtagtg gtacttatgt tgccagccat
     7861 cgcgtacaag agagaatgcg tgggaccact agctttacag agatcgtgaa ttctcaggga
     7921 cgtaagccat cttcaaaact gatttcctat caacgtcagc tagcaagtga tacagaaata
     7981 aatcaattgc acttagaaga atcagattac gttattcgaa tggagcgcat tcgttatgca
     8041 gataaggttc ccttagttta cgaggtagca tctattcctg agaaatttat taaaaatgtc
     8101 aaaaaaactg atattacaga gcactttttc caaaccctaa cctcaaacgg ttatgaaatc
     8161 ggcaaaagtc aacaaaccat ttacgcgaaa atagccagtg agcgtgtcgc ctcttatcta
     8221 gaggtcgcta aggggcatgc tattttagca ttgactcagg tttccttttt tacagacggt
     8281 aggccctttg aatatgtgcg tagccaatat gtaggtgatc gctttgaatt ttatttagaa
     8341 aataattaat cataagcaat gatgtttaaa taacattgat aggaagtggc tcaccacttc
     8401 tttttttcaa cacttgtcaa gtatatcaat atttcaagaa cagttattaa aacaagctac
     8461 tattatcctc atttttgctc taagaaagct tcctgataaa aggctgatcg ctatcattta
     8521 ccactgttaa aaatgctcat gatgtgataa aatgaagatt atggaaattg aaaaaacaaa
     8581 ccgaatgaat gctctttttg aattttatgc tgccttattg actgataaac agatgaacta
     8641 tatcgagctc tattacgctg atgattatag tctggctgaa attgctgaag aattcggtgt
     8701 cagccgccaa gcagtttatg ataatattaa gcgcactgaa aaaattctgg aagcctatga
     8761 aatgaagctt catatgtatt cagattatat tgtacgtagt gaaatatttg atgatattct
     8821 tgcaaaatat cccagtgacc actatttacg tgacaaaatt tccattttaa ctagtattga
     8881 caacagagat taagaggagt tatagctatg gcatttgaaa gcctaaccca acgtttacag
     8941 gacgttttta agcacattcg tggtaaaaaa accttatctg aagccgatgt tcaggaagtg
     9001 accaaggaga ttcgtctagc cttattagag gcagatgttg cacttccagt tgttaagacc
     9061 tttatcaagc gtatacgtga gcgagctgtt ggccacgaaa ttattgatac ccttgatcca
     9121 acgcaacaaa tacttaaaat tgttaatgag gaattaactg gtatcttagg atcagaaacc
     9181 gcggagcttg ataaatcacc taaaatccct actgtcatca tgatggtggg cttgcaggga
     9241 gctggtaaaa cgacctttgc aggaaaatta gccaataagc tcatcaagga agaaaatgct
     9301 cgtccattga tgattgcagc agacatctat cgtccggctg ctattgacca gttgaaaacc
     9361 ttgggacagc aaataaatgt tcctgttttt gatatgggga caaatcattc agcagttgat
     9421 attgttgcca atggtttggc acaggcaaaa gagaaccgtc atgactatgt tttgattgat
     9481 acggcaggac ggttacaaat tgatgagaaa ctaatgggcg agcttcgtga ggttaaagca
     9541 ctagctaaac caaacgaaat ccttcttgtt gttgacagca tgatcggaca agaagctgcc
     9601 aacgttgcct atgaatttaa caatcagctc gatatcactg gagtagtgtt aacaaagatt
     9661 gacggtgata ctcgtggtgg tgcggccctt tctatacgtg aaataactgg taagccaatc
     9721 aaatttaccg gaactggtga aaaaatcacc gatattgaaa ccttccatcc agaccgtatg
     9781 tcaagtcgta tcttgggaat gggagacctt cttaccttga tcgaaaaagc aagtcaggaa
     9841 tatgatgaga aaaaatcatt agagcttgcc gcaaaaatgc gtgagaatac ctttgatttt
     9901 aatgacttta tcgagcaatt agaccaagtg caaaacatgg ggccaatgga agatctgtta
     9961 aaaatgattc caggtatggc aactaatcct gctctagcca atattaaggt tgacgacaag
    10021 caaattgctc gcaagcgtgc tatcgtttct tctatgacac ctgaggagcg tgagcagcca
    10081 gagcttttaa caccaagtcg ccgccgtcgc attgcagctg gatcaggtaa tagtttcgtt
    10141 gaagtcaaca aatttattaa agattttaac caagccaaag ccatgatgca gggtgtcatg
    10201 tcaggtgata tgactaaaat gatgaaacaa atgggaatca accctaataa cctccctaaa
    10261 aacatgccaa atatgccagg aggcatgcct gatatgtctg cccttgaagg aatgatgggg
    10321 caaggtggtt tacctgacat gtctgcattg ggtggtgata tggatatgag ccagctcttt
    10381 ggaggtggtc taaagggtaa gattggtcaa tttgccatga agcaggccat gaagcgtcaa
    10441 gctaataaga ttaaaaaggc caagaaaaaa cgaaaataga ctaaaagaat ggttgccttg
    10501 tattctgcct ctaatcgtta gatgctattc taatttggag tgcaggtcag tagcgaccat
    10561 cttttttata aatacaatca ctagatcttt ggttctaacc attaaacatg atatcatttc
    10621 actattagct gttagtgcct gtgctttaat tgctttctga tcttatatag caaattagcc
    10681 aagtgataaa aaggactgat tgctaggttg aattctccaa taaactcttc gatagttgga
    10741 ctgaaattgg acttaaatgc tgtcaatccg tccttgaagg agccatcaat gccgcccata
    10801 ttcgcccaag ctatatcatc atgataggca tccataaaga ctttaggata aagcaggtac
    10861 tgaggataaa actttttaaa gtcatcattc atgccagcat agagcatttc catcgtgttg
    10921 ccatatgaaa tcgataaaat gcccgcaatg acaacctcat ctggatattt atccaagaag
    10981 tccttgaatt ctgatagata acgctgaagc gattgctttt gatctgttag tctagccagt
    11041 cgcttttttt gatgcgcttg cgtttgagca agctcttgtt caacagcttt cagctgaagc
    11101 tcgtaattct tgagtttttc tggaagatta acctttgcta aatgcaaata agcattgtcg
    11161 ccataagtcg tcatcagctg tctaaaataa gcttcgtttc ttagagcaac tccttttctc
    11221 ttttcagtta aagagataag gtcagcaaat gtatggagat cagactgatt acctcgataa
    11281 gctatcacgc cacgttgcct agcatccttc atcaatcgct tggtatgctt aggaaaggac
    11341 gcttcaatat cagcattagt gtaacaattt gcttgaaaac gcggctgaat agtatcagat
    11401 agcttggttg ttgggcctgt ccaatgggca ccaaatcgct ttaaatgctt aataatggtc
    11461 agagccttgg aattatcagg tgctttctca ccaagctgat gctgctttag cagaatcata
    11521 ggatcaaatt taatcaaaag agctcttttt ttcttaccat atgccttcaa ggttttaatc
    11581 gtaaatgcca ctagatcagc attggtatag tccatcactg gacctcttgg aatataaatc
    11641 atcgtcatac caaacggcaa aggcttaatc agcaaggaca tagaagccac ctgattatct
    11701 ccctgaaaaa taccgatgcg ttcattttgc cactgatttt taacagctgc ccatgagctg
    11761 ctctgcaaga ggttaacctg ctggtgctgt ttgacaaatt ggtcatgctc ttgagctgaa
    11821 ataccgattt ttgaattaaa agctacattt atcatcatat ttcctcatct ttaagtatct
    11881 aaa
//
LOCUS       DARYVE010000061        11600 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYVE010000061 DARYVE010000000
VERSION     DARYVE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11600
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(728..1744)
                     /gene="adhP"
                     /locus_tag="TVW25_001622"
     CDS             complement(728..1744)
                     /gene="adhP"
                     /locus_tag="TVW25_001622"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1379237.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            complement(1947..2999)
                     /locus_tag="TVW25_001623"
     CDS             complement(1947..2999)
                     /locus_tag="TVW25_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1379238.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            complement(3494..6136)
                     /gene="adhE"
                     /locus_tag="TVW25_001624"
                     /gene_synonym="adhC"
     CDS             complement(3494..6136)
                     /gene="adhE"
                     /locus_tag="TVW25_001624"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1379239.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            complement(6556..8337)
                     /locus_tag="TVW25_001625"
     CDS             complement(6556..8337)
                     /locus_tag="TVW25_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1379240.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            complement(8334..8735)
                     /locus_tag="TVW25_001626"
     CDS             complement(8334..8735)
                     /locus_tag="TVW25_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379241.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            complement(8741..9199)
                     /locus_tag="TVW25_001627"
     CDS             complement(8741..9199)
                     /locus_tag="TVW25_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1379242.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            complement(9440..10447)
                     /gene="ruvB"
                     /locus_tag="TVW25_001628"
     CDS             complement(9440..10447)
                     /gene="ruvB"
                     /locus_tag="TVW25_001628"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1379243.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            complement(10481..10579)
                     /locus_tag="TVW25_001629"
     CDS             complement(10481..10579)
                     /locus_tag="TVW25_001629"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1379244.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            complement(10662..11575)
                     /locus_tag="TVW25_001630"
                     /pseudo
     CDS             complement(10662..11575)
                     /locus_tag="TVW25_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         3529 a         2587 c         2000 g         3484 t
ORIGIN      
        1 aatttctttc ataaatccac ctaaaagatt ttataaataa attataatgt acaagtatcg
       61 tatcctaaaa aacttccctt attcgggaca caacattttt catctatatt ttaaatcata
      121 ctaccttgtt actaaaaacg tagataataa tttagcttat aacccatgtt tttagcaata
      181 tgttatgtca ttattctttt ttcctacagt gcttcctaaa atttgtgaag acgaattgtc
      241 aaattaagtg caacgctttt ccataaaaga gtttataagg tagtttccag ttaggacatc
      301 ttctagaacg atcatttcat ttatcttccc actcttatat gatagagctc tcaatatcag
      361 tcaagtcagt tcctttagga aactactctt tgattaaccc attggtattt tcatttgtcc
      421 tacgttatca aggggtgtga ggagcagaga aataaacttc tagattgagt tcctgtgtta
      481 atctctaata ttgttcaaac ccagtatctc tatcagaggt tacaatatgt ccaactttct
      541 ctggtactgt ctttcaaggg gcaatcatgg tattaataac tagctggctc ttttacatct
      601 ttagatacca agcttttttt accagttagt ttcaccaaaa aagcccttag aaaattaatt
      661 ctaaggactt tattcatcat ttgggacaat cagcttgtct ggctgctgac tttttctgaa
      721 atcagcctta aagcgtgaaa tccaatacct ttcttccttg aatgagacca cgttccattt
      781 cgtcaaagac ttctggagca gtctcaactg gaaccttttc tacaactggc acaaccagac
      841 cttctgcacc aaaggcaaag gcttcttcca agtctttacg agttcccaca agtgatccga
      901 ctaccttgat tccgtctagg acagtcttta cgatagataa ttccatgtat tctgatggaa
      961 gtcctacagc aacaacagtt cctcctgcac gcacactatc aatagcttgg ttaaaggcta
     1021 ctttagaaac agcggttacc acaacgccat gagcaccacc tgttttttct tggatatagc
     1081 cggcaacatc ttcgatttct ttaccattga caacgatatc tgctccaacc tccttggcca
     1141 gctctagctt atcattgtta atgtccactg ctacgacatg agcattgaaa acctttttag
     1201 catactgaac agctaggtta ccaagtccac cggcaccaaa gataacaatc cattgtcctg
     1261 gagcggcacc tgcttctttg atagccttat aggttgtaac gcctgcacag gtaattgatg
     1321 atgcttgagc tgggtcaaga ccatctggca ctttcacagc atagtcagct gtaacaactg
     1381 catactcact catcccacca tcaactgaat agccagcatt tttgactgaa cggcatagag
     1441 tctcgcgacc tgttgtacaa tattcacaat gaccgcagcc ttcaaagaac caagcaattg
     1501 atacacgatc accaaccttt aaggaggtaa cgccttcacc tagcttttcg acaataccga
     1561 taccttcatg accgaggata cgccctggaa cctgaccaaa atcaccatgc gcaacatgca
     1621 agtcagtatg acatacgcca caatattcta ctttaacaag agcttctcca tgaccgattg
     1681 atggtacatc atgctctaca acctctacac cactgctggt ttggttaaca actacagcct
     1741 tcataggatg cctccaattt ctaagtctcg gtttatctat ttttgcaacc gtttacaatt
     1801 tgtattgtat actttttcac aaggtttgtc aaccaatttc ttgaaagttt tctgaaaata
     1861 aacttaacca gttaagttgg ctaaaaaaca gcatctagac cattccaaat gctgttgtca
     1921 cttttatcta tttatacctt attcctttag gctgtaatgt cattttcaat aatcacttta
     1981 agggcgttat tactgccggc atttttaaag acctcatagg ctttttcaac ctctgacagc
     2041 ttaaagtgat gtgttaccat cttagttgca tcaatcttac cagatttcaa cacattcaat
     2101 agcatttctg ttgtattagc gtttactagg ccagttgaca ttgtaatgtt tttgatccat
     2161 aggtcctgta ggtccaaact aactggtttt ccatggacac caacgttaga aacatgcccg
     2221 ccaatagcaa taatcttttg gcaaatatca aaggtagcag gatagcctac acactcaatg
     2281 gcaacatcaa cacctcgacc atcagttaat tcatggactt ttttgacaat atcatcaagg
     2341 tcaccagagc aaatcgtatc tgttgctcca aagcgcttag ctgcttctaa acgtgattct
     2401 gacaagtcaa ccatgatcag cttagctggt gaataaaatt gtgctgttaa aagagctgct
     2461 agtccgatag gacctgctcc aacgatacac actgtatcac ccggctttac ctttgcagac
     2521 tgaacgccta tttcatagga agttgggaaa atgtctgaca gcataaccaa ggcatcatcc
     2581 tcaacggttt taggagcatg ataaagactg ccatctgctt gaggaatatg aacatactct
     2641 gcttgtgtcc cattaatcaa atgccctaga atccagccac cgctttcaca atgagcagga
     2701 attccttttt tacaataata gcaggtatta caggctgtga tacaggaaat aataacctta
     2761 tcacctacct taaagttgtt cactgcagag ccgactgact cgacaatacc aataccttca
     2821 tgacctaaaa tggtaccatg agtagtctct gggacatctc cacctaaaat atgtaagtct
     2881 gttccacaga ttgttgtttt caataaacga accacagcat ctgtcggagc aagaatctct
     2941 ggttttggtt gatcaataag ctccagctga cctggagcaa catatgtagc tgctttcata
     3001 aaacgtctcc aaatttagtc tagaaaatgt aatcgattac atttttagta taatttttta
     3061 caccctcttt gtcaattaat aaagggtaat tttagaaaaa gtctgacaat accattattt
     3121 tggtttttgt ttgatatata aaggttttta acgctattaa catcattaaa aaagcaatca
     3181 ctccttgttt tattagaaaa taaagctcat cagatagacg caacatgtta ttttcttcag
     3241 ctaattgcta agtgcagcta agtcgtaact atcagccact ttatgaatat ggcaaatgaa
     3301 gcttccccct ctgatggaat gctctgtaaa accattgtct taaaagcttt atatgatatc
     3361 tgagaaacta cccctgagtt aagctatctc aacacaaggc actgccgact ttttcatcta
     3421 acacagccct tttcatagct agataaaaaa atagaagcca agcagctcct atttttacta
     3481 ttaatgattg atattatttc cgacgtcctg gacgctctgc gtaaccataa taagcatcat
     3541 tcatgatttc ttccatgtgc tcaaccattg gcaagcgtgg gttagcaggt gagcattgat
     3601 cctcgtaggc aagataagca agctcacgag tgtgtgcctt ccattcttcc tcatcaattc
     3661 cttgatctct gaaattcatc ttaatgccta agcgacagcc aagatcataa acagctttag
     3721 cataagattc aacaccttct tctggagtag atgccggaag tcctagcaac ttagcaatgt
     3781 cttgatattt ttcatcggcg cgatagtaat tgtacttagg ccatgttgct gttttagcag
     3841 gacgggtacc attgtaacga ataacgtatg gaagcaagat agcattggta cgtccatgaa
     3901 cagtatggaa ttgtgcacca atcttatgag ccattgagtg agaaataccc aggaaggcat
     3961 tagcaaaggc catacctgcc attgttgagg cattatgcat tttttcacgt gactcaaagt
     4021 cagcttcctt aacagatttt tcaaggtttt caaagacaat cttaatggct tgaagggcca
     4081 aaccatctgt aaagtcatta gccatttgtg atacgtaagc ctcggttgcg tgggtcaaca
     4141 cgtccatacc tgtatcagct gcaatgaagc ctggtactgt aagcaccaac gccgggtcaa
     4201 caatggctac cgttggtgtc aatgaatagt cagcaattgg gtacttgcgg ttgttggcct
     4261 tatctgagat aacagcaaac ggtgtaacct ctgatcctgt acctgaggtt gttggaatag
     4321 ccacaaattt tgttttctta ccaagctcag ggaacttgaa ggcacgttta cgaatatcca
     4381 tgaatttttg aacaagatca tggaagtcaa cctctggttg ctcatagaat aaccacatta
     4441 cctttgcagc gtccattgga gaaccaccgc caagagcgat aatcgtatct ggcttgaagg
     4501 tacgcatcag ctcagtacct ttcataaccg ttgtgatatc aggatctggc tcaacatctg
     4561 caaaaatttg ataaacaacc ttattacgac gaaggtcaag ctgctcgatg atacgatcta
     4621 agaagccaag ctcaaccata gcgtggtcgg taacaatcat cacacgctca acgtcacgac
     4681 atttttgaag gtattgaatt gaatcacgct cgaagtatgt ttttgaagga actttaaacc
     4741 attgcatatt atttctacgt cttcctactt ttttgatgtt caagagattt acagcactaa
     4801 cattatcacc aactgagtta cgtccataag aaccacagcc caatgttaat gacggtagga
     4861 aggcattata aacatcaccg ataccaccaa atgtagaagg tgaattccaa atcacacgaa
     4921 tagcacgaat ttttgttcca aattccttag ctaagtctgc atcagcagta tgaatagcgg
     4981 ctgagtgacc aagtccgtta aattcaacca tttgacgagc cttttcaaca ccatctgtgc
     5041 gagattcagc cttcaaaaca gcgataactg gtgacaattt ttcacgtgtt aatggctcat
     5101 tttcagaaac ttccttacat tctgctgcaa ggatattcgt tccttctggt actgtaaagc
     5161 ctgcctgctc agcaatccaa gctgctggct taccaacaat attagggttc agcttagcac
     5221 ctgcacagtt tttactgtta gccttagcac caaagcagaa ttcctctaac agagcctttt
     5281 cctttttgtt gacaaagtaa gtgtggtaag acttaaattc actaacaaac tcgtcataaa
     5341 tctccttgtc gataataaca gcctgctcag aagcacaaac cataccattg tcaaatgatt
     5401 tagacatgac aatatcgtgt gctgcctgac gaatgttagc ggatttttca acataggcag
     5461 gcacgttacc agcaccaacc ccaagagctg gcttaccaca tgagtaggct gccttaacca
     5521 tagcattacc accagttgca aggattgttg caataccatc atgattcatc agagcgttag
     5581 ttgcttctag tgatggggtt tcaatccatt gaacacagtc ctcaggagct cctgctgcaa
     5641 tggctgcatc acgaacaatg cgtgctgcat gagctgatga ttcttgagct gatgggtgga
     5701 aggcaaaaat aatagggtta cgtgttttta aggagattaa agatttaaaa atagctgttg
     5761 acgttgggtt agttgttggg gtaatcccac aaataacacc tactggctca gcaattaagg
     5821 tcaaacctgt tacatcgtct tcttcaatga tacctactgt tttttggtga cgcatgttat
     5881 taacaacgtg ctcacatgcg aaaaggtttt tggtagcctt atcttcaaaa actccgcgac
     5941 cagtttcttc ataggcatgc ttagctaact caccatgtgc gtccaaagca gcaacagagg
     6001 ccttcgctac aatgtagtca acctgttctt gagttaactg acgcatttta tcaagcgcta
     6061 ctaaaccttt ttgaacaaga gcgtcaattg ttgcggcaac agatgttgtt tcaacagtac
     6121 tatttttttc agtcatttga gactccttta ccttgttaaa agtttcacaa ttttgtttac
     6181 aaaaatatta tatcattttt tggcattttg taaatcattt cacaataaaa ttgtgatgtt
     6241 ttttcaatca atttccgaaa ctctttgata acaaggggtt tggcttggtg gattttttct
     6301 gaaataatgg ctgacgcatt cactttgttc cgaaagcgct ttctttttta gatcaggcta
     6361 aattatttaa tgatccgttt ttaaaagcac gtcaccgtca gcaataacag ccaataatga
     6421 cactgtctaa caggtggagc tttatctcgc gctaaagggc gcaagacgat ctaaaaatca
     6481 catcatgaaa aggcttgatc tgtttgtaag accaagcctt cgttattaat tcttaacaaa
     6541 ttgttgttag caccactatt tagcatcttt ttttgctgct cgctcaacag ccgcctgaat
     6601 cgttgagaca tataagtcag caccttttaa tttggcgtcg ttattgtagt ggaccccatc
     6661 actaccatac cagatattgg gattttcgac tgccgccttg taccagtcag caactgttac
     6721 atagctatat tttttagcta gctgcaacaa atgctctcta gcctctgcta cctgtgctgc
     6781 attcttagca tcatagggcg acacaatcac caagcgatgc ccctttggta gtgcataaat
     6841 aaagccttga atatcctgcg cataattata aagagaatta acaccaacag ctaaaaccgt
     6901 tgtttttgat aagctcttgg attggatatg attttcaaaa agctcaaagg cttcactgaa
     6961 attgcggctg acagcagcgt ctagttgagc agtcggcatt aattttgaaa aagcgtcact
     7021 agacctcaag gcaactgagt caccaataat gctaacatca ctaagagcat gcgcatctcc
     7081 tgctgccaaa gtatgtgtct tattgagatt actttgagat tgctgcaagg aatctactaa
     7141 aagctgggtc tcaaaattac cgacccttgg tgctgtcaaa caggtaccaa ccatcaacaa
     7201 aaagagtcct aaagcaagcc ctgataacca tttcttatag ggattacaat caattgctaa
     7261 accaaaaagc tgtggtgtct tgccttgaat caaaggctca ataatgtaat aagaaagcgt
     7321 tgaaaacact actgaaaaga aaaccgttaa gatcactgcc agccagttag acatcagctg
     7381 tgtaaaaata atgtaaaatg gccaatggaa taaataaatc ccatagctaa tatccgcaag
     7441 ataggtcaca agcagtggtt cctgccaggt tggtgtttga tcgctcaaaa cacgcgcagc
     7501 ataaatcatt accgaagcaa aaagactggc taagacaaaa ccgaaaagat aggtaaagat
     7561 atggttaaaa tctaacacaa gcgttagaaa caacaacaga gcaaaagcgc cagccatcac
     7621 tccaataaca tgtagccttg gccacagctt aacattcttt tgaaagcgaa cagtcgtgtc
     7681 cttaattccc gtcatggttg caaacatcgc tcctaaaaag aaaggaaagc tgtgtgaaag
     7741 cgttgaaaag taaacagaag aaaaatctga tacaaagaag gctctgataa acatgctgaa
     7801 gtagctaagc gtgaacactg cggaagaaat taaaaacaga atgcctctaa atttcttctg
     7861 actgtagcct tttttagcta ataaccaaac caacagcccc caaagcaaat aaaaatgcac
     7921 ctcaatggcc aagctccagg tatgcacaaa cagatgcgga atgaattgac tttcatagct
     7981 actgcctgtc agtagctcat aactatttgt tgtaaaccct agggcagctg ctatttgctg
     8041 accgatacca gcaatgaagt cacttttgac taaaaaagta aagggaattg tcaagagaat
     8101 taacaagaca agcggcggta caatacgata aaaacgcctt ctaaaaaaag caaccacatc
     8161 aatggtttgt tttgagacat attcatcaat caacaaggct gtaatcaaat agcctgaaaa
     8221 agtaaagaag atgtcaacgc caacaaagcc tcctgaaaaa gtatgcttaa aaaagtgata
     8281 gagcaacacc agcaaaagac ctgttaccct aataaacgaa aaccatttta tcctcatttt
     8341 tgaaatatcc cctgcttaaa ggttcctttg taaacctttg aatccttcgc cttcaaagta
     8401 cccttgccat cagcctgacc ttttttaaat tgtccgctgt aagaccaccc tgtactagct
     8461 gtaaacgttc cttctccatc aaagacacct ttattaaaat ccccaacata ggtatcgcca
     8521 ttagggtaaa ccaatttccc tttaccattc attctatgat taaggacata gccggtgtac
     8581 ttgatttgcc cattgtcata ggtcaagctt gcttttgagg atatggtcaa ggtaaaaacc
     8641 gacaatccac agacaataat cacaaggact gaaataatct ctagctttgt ccgagtgatc
     8701 tgccattttt gaatgttatt tattattgct ttcattacta ttactcatct atttccacat
     8761 gtgattcatg ttcagcgctg atttgactca accaatgctg acagcccgct ttaaccaagc
     8821 ggtaggtttc ttcaaaatct cctgtatacc aaggatccgg aacgcctcct tcaataaaaa
     8881 gatggatctt ggaatcccac tgatgcttgg acatttgctt caaatctctg atattatggc
     8941 tatccattcc gataatatag tcaaaggctt caaagtcaaa gctggtgatt tgctgagagg
     9001 ttttcttggt atcatagcta atctgatatt gctgtaatag cgattgtgtc ccatgatgaa
     9061 ttggattgcc atgctcccag ccagaggttg cacgactctc cacctgtagc tcatcaggac
     9121 tggccatact tttcatgaca aattcggcca taggactacg acaaatattt ccaagacaaa
     9181 caaagcatac ttttttcatg aaaaactcct tttacctatt atagcaaaat tatagggcca
     9241 aaaggagaaa tcgctcttat aattttcgtt caattgatct aaaaatgttt tttaatgctt
     9301 tgtctagtga aagcacctct gcttccctga ccaatcaccc ctcacctcac atcgttttac
     9361 ttttttactc agtaagctat tgacaataca aaagacttga caccggtaaa aacaaaggaa
     9421 tcaagtctta catagctatt tatgtcttaa tggttttttc atagggatag cctaagtgct
     9481 gataggcttt ttcggtgaca actcggcctg ttctggtacg catgataaaa cccttttgaa
     9541 ttaaataagg ctcgtacatg tcttctactg tatctcgctc ctctgctata ttgacagata
     9601 gagtcccaag accaaccggc cctccttggt acacctcaat catggtacga agaatctttt
     9661 ggtccacata atctaaacct tcttgatcca catctaacat cgttagagcc ttatctgtga
     9721 tttgagtcgt aatcattcca tcacccataa tttgagcata atcacgcacc ctttttaaca
     9781 gccgattagc aatacgaggg gttccacgac tcctgcgtgc cagttcataa gcggcctcat
     9841 gcttgattgt catgtcaaaa atatcagctg tacgctccac aatctctgtt aaatcagctg
     9901 tctgataata ttccatatgc ccagtaatcc caaaacgagc cctcaaagga tttgacagca
     9961 tgcctgcacg agtcgttgct ccaattaatg taaagggagg cagctccaaa tgcacactcc
    10021 ggctagtgtc tccagcgcca atcatgatat caatgtaaaa atcctccatg gcactgtaca
    10081 agatttcctc aacagccatc ggcatacgat gaatttcatc aataaagagg acatctcctg
    10141 gctctaaatc attcaaaatt gccaccaaat caccagcttt ttcaatggct gggccagagg
    10201 tctgcttgag atgaactccc aattcattgg caatgacaaa ggccatcgtt gttttaccca
    10261 agcctgggga accaaataac aggacatgat ccaaggattc ctcacgcctc ttggctgcct
    10321 caataaaaat catcagctgg tctttaaccc tatcctgacc aatatactca cgtaaatact
    10381 gtggacgtag tgtcctctca acagatcctt catcgcctat cagatcatta tctaaaattc
    10441 ttgtcataga gctattatag cataaataga tgatttagct ttaaccaaca cgccaccagt
    10501 caatatcact aagtaattgg gcagaatgaa gtagaaataa agcagctaaa aacagatagt
    10561 attggtattt tttaaacata taaatggaac tcctttaatc aattatttgt tatataaaga
    10621 ttatatatta ttccattttt gataaaaatg acatttttgt cctattgata tcgttttata
    10681 tctttacccc attcttctct caatttcttt tccaaatact gatctcctgt taattgagca
    10741 aacaggcatg ccttagcata gcattttttg gccatttcta tgtctttttt cttcattaga
    10801 gcatatttcc actctatcaa atttaagata ggcattctat taaaatcctg agtcttgagg
    10861 ataatttttt gactaagtac aataaccttc tcaagaatct ccggcttatt gtttttgatg
    10921 ctcaacgagg aaattcctat agctatttta ttgacaataa ataattcctc taattcaaaa
    10981 tgttcaaact gatttaacaa aatgtctaac aaagaatcat agaatccttt atctgaatac
    11041 tctccattca ttcctgcaat gtcgaggtac gctaaataca gctcaataag aatgagatca
    11101 ttctctctaa attgagtctt actttttgtt tgttcaaagt attcctgtaa taacccaact
    11161 ccaaaattga tattctcggt taataacgta tccattatgg actgcaagca atccaccaca
    11221 agcttttctt cctctggcaa ctggtcataa taatcttcaa aaatttcgtc aaattgctct
    11281 tctcgcagct ttaatttgtc atcgtccata taggtcggtg ttcttaaaat caaatattta
    11341 agctcctata gcgcttcggt agctccaaat cctctccgtc tgtcaaaaag ccgacactaa
    11401 cgtccaaagc cttagcaata aaaaccacct ttgataggct gggaatcgat tggcccagtt
    11461 ctattcgtgc caattgacga atggataatt ctgactcatc tccacataaa tcctctctgg
    11521 taattttttt ctgataccga aggtctctca ccttttcacc aaaattgtct aacatgtttc
    11581 cctcttcaag acactatttc
//
LOCUS       DARYVE010000062        11438 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYVE010000062 DARYVE010000000
VERSION     DARYVE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11438
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(72..2753)
                     /locus_tag="TVW25_001631"
     CDS             complement(72..2753)
                     /locus_tag="TVW25_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1379245.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TVW25_001632"
     CDS             complement(3101..3487)
                     /locus_tag="TVW25_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1379246.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TVW25_001633"
     CDS             3568..4869
                     /locus_tag="TVW25_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1379247.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TVW25_001634"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TVW25_001634"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1379248.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TVW25_001635"
     CDS             5903..7117
                     /locus_tag="TVW25_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1379249.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TVW25_001636"
     CDS             7117..8352
                     /locus_tag="TVW25_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1379250.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TVW25_001637"
     CDS             complement(8561..9319)
                     /locus_tag="TVW25_001637"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1379251.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVW25_001638"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVW25_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1379252.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3437 a         2588 c         2264 g         3149 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc tatcgtggtc gatgatcgca gagttagctt gttaatattt
    11341 tctatctttt ttattatatt ttgttaattt tataatctat ttaactattt taaaaattta
    11401 cttatttaaa tcacaaaaca ctgttataat aacgtttt
//
LOCUS       DARYVE010000063        10997 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYVE010000063 DARYVE010000000
VERSION     DARYVE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10997
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(32..1213)
                     /locus_tag="TVW25_001639"
     CDS             complement(32..1213)
                     /locus_tag="TVW25_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1379253.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TVW25_001640"
     CDS             complement(1297..2532)
                     /locus_tag="TVW25_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1379254.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TVW25_001641"
     CDS             complement(2854..4092)
                     /locus_tag="TVW25_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1379255.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TVW25_001642"
     CDS             4400..6376
                     /locus_tag="TVW25_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1379256.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TVW25_001643"
     CDS             6440..7939
                     /locus_tag="TVW25_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379257.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TVW25_001644"
     CDS             7939..8865
                     /locus_tag="TVW25_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379258.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TVW25_001645"
     CDS             8874..9944
                     /locus_tag="TVW25_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379259.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TVW25_001646"
     CDS             9937..10860
                     /locus_tag="TVW25_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379260.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3259 a         2144 c         2282 g         3312 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagtat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctatttacaa
    10981 aaaacctgtc aaaacct
//
LOCUS       DARYVE010000064        10981 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYVE010000064 DARYVE010000000
VERSION     DARYVE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10981
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            159..515
                     /locus_tag="TVW25_001647"
     CDS             159..515
                     /locus_tag="TVW25_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379261.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            1039..2088
                     /locus_tag="TVW25_001648"
     CDS             1039..2088
                     /locus_tag="TVW25_001648"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1379262.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            2419..2661
                     /locus_tag="TVW25_001649"
     CDS             2419..2661
                     /locus_tag="TVW25_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379263.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(2783..3997)
                     /gene="thiI"
                     /locus_tag="TVW25_001650"
     CDS             complement(2783..3997)
                     /gene="thiI"
                     /locus_tag="TVW25_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1379264.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(3999..5141)
                     /locus_tag="TVW25_001651"
     CDS             complement(3999..5141)
                     /locus_tag="TVW25_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1379265.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKSAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            5381..5821
                     /locus_tag="TVW25_001652"
     CDS             5381..5821
                     /locus_tag="TVW25_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379266.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(5891..7243)
                     /gene="gorA"
                     /locus_tag="TVW25_001653"
     CDS             complement(5891..7243)
                     /gene="gorA"
                     /locus_tag="TVW25_001653"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1379267.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(7437..7778)
                     /locus_tag="TVW25_001654"
     CDS             complement(7437..7778)
                     /locus_tag="TVW25_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1379268.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(7839..9005)
                     /gene="aroC"
                     /locus_tag="TVW25_001655"
     CDS             complement(7839..9005)
                     /gene="aroC"
                     /locus_tag="TVW25_001655"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1379269.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(9118..9798)
                     /locus_tag="TVW25_001656"
     CDS             complement(9118..9798)
                     /locus_tag="TVW25_001656"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1379270.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(9795..10958)
                     /locus_tag="TVW25_001657"
     CDS             complement(9795..10958)
                     /locus_tag="TVW25_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1379271.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         3319 a         2511 c         2013 g         3138 t
ORIGIN      
        1 aatttaatta ttccaaaagc tacatttatt taatttttta aaaacacttt attaatttaa
       61 ttacaaaaac atttgacttt tgacagattt tgagttaaac taacattgtg ataaggaaaa
      121 tatcacaaaa ataacgacgg acaaaggaac cgttggaaat ggaggacact tatatgacac
      181 aagcttgtaa gaaatttatg gtttctacaa tggctgccct agctttggca ggagtctgcc
      241 taacagcttc aacccacatc agcaaagctg atgactatgt ttatggtgac gtggaatatc
      301 ttttgacgcc taagcaagaa ggatacgatg atttggtgtc attcttggag agtctaggcc
      361 ttaaccattt tgatgccact ctttattcgg actctatggc tgatcaagat tacaaaaagc
      421 tactagctga ctttaagggt aaaactcgta gtgaagttat ttctgcagtt ctatctgaat
      481 tagctaaatt ttataacgac tattcccctt tttaatgaaa taacccaata agttatcata
      541 gatcaaaact gctcagacaa ccttccgagc ggttttaact tgatagagct atgcttctct
      601 ttgtcaatct gcttagtaac cagaccatct cctaaatcgt ccgcctagct aatcaagtaa
      661 taactgcacc attgtcctta ctatcctagc taatgccctg atttgctgac taagcttggc
      721 taagattgtg caagaatccc aataacatca aagcctacac tagctcttat tagtggtctc
      781 aataataaca gctcatgtct aaggcatgac accaacaata ccaaacggta tcatcattgg
      841 taaaataggt aacgctaaca taaaccaagc tgaaatatcc attatagaga tccagtctgc
      901 cagcatctct actatctcat cactatttac taataaataa agcttatcaa aagcattgtc
      961 tcaacaaaat attgtgataa tatataaatg tcattaacat tatttaatga taatatcacc
     1021 ataacaagaa agggttatat gaaaacaata gcttatccaa ataaacctca ctccttatca
     1081 gctggtctct taactgctat agctattttt agcctggcga gttcaaacat tacttatgct
     1141 gacgattacc aaaggaatgc tacggaagct tatgccaaag aagtaccaca tcagatcact
     1201 tctgtatgga ccaaaggtgt tacaccacta acacccgagc agtttcgata taataacgaa
     1261 gatgtgatcc atgcgccata tcttgctcat caaggctggt acgatatcac caaggccttc
     1321 gatgggaagg ataatctctt gtgtggcgca gcaacggcag gtaatatgct gcattggtgg
     1381 tttgatcaaa ataaaacaga gattgaagcc tatttaagta aacaccctga aaagcaaaaa
     1441 atcattttta acaaccaaga gctatttgat ttgaaagctg ctatcgatac caaggacagt
     1501 caaaccaata gtcagctttt taattatttt agagataaag cctttccaaa tctatcagca
     1561 cgtcaactcg gggttatgcc tgatcttgtt ctagacatgt ttatcaatgg ttactactta
     1621 aatgtgttta aaacacagtc tactgatgtc aatcgacctt atcaggacaa ggacaaacga
     1681 ggtggtattt tcgatgctgt tttcaccaga ggagatcaga caacgctctt gacagctcgt
     1741 catgatttaa aaaataaagg actaaatgac atcagcacca ttatcaagca agaactgact
     1801 gaaggaagag cccttgcttt atcacatacc tacgccaatg ttagcattag ccatgtgatt
     1861 aacttgtggg gagctgattt taatgctgaa ggaaaccttg aggccatcta tgtcacagac
     1921 tcagatgcta atgcgtctat tggtatgaaa aaatattttg tcggcattaa tgctcataga
     1981 catgtcgcca tttctgccaa gaaaatagaa ggagaaaaca ttggcgctca agtattaggc
     2041 ttatttacgc tttccagtgg caaggacata tggcagaaac tgagctaacc agtcatcatt
     2101 aggaacagac caagtgctta ttggtctgtt ttttcgtcta acaatagccc tattagctca
     2161 ctgtcattgg ttaaagcttg tcatgaactc tttaagctct tgttttgtta aacattaatg
     2221 tgcctgttgt tcttttctaa gataagtaaa ctagatacct gacataaaaa acaaacgtta
     2281 ttatttatct taataaaaaa atcatttttt gaacataaaa tacgaatatt atactaaaaa
     2341 taaatccaaa tagtttacaa tttatggttg ttttcatata attttcatga aaggagggaa
     2401 atatatgaaa aatctatatt gataagttgt acactattag ccagtctctt attaactggc
     2461 tgtcactcat tgtctttgca gctagctgag gctgttcagg aaaagcctat tcaagcggtt
     2521 acggtagagg atttgaccag acatggcatt gccgaatcct tgaaagccta cctacagacg
     2581 atgggcttaa ccaatgaaga ggctatgaaa caatacgagg aggtcctttc tgatgagatt
     2641 atccagtatt ttagcagcta aataagagaa tttgagcaaa atcagctaaa aacaaaagcc
     2701 agagccttta ataactaata ggtctggctt tttttgactg tttagataga ctgcttatgt
     2761 tgtagggcta ggtgcgcacc tcctacaaca attcctcaat aagcgttgat aagctgtcag
     2821 tttcgatttc aggagtgatc tcagttactc tgatccctgc cactgctcgc tcgaccaatc
     2881 cgtcgacatc aaagcgagac tcatatcgtt caacatttgc tagcttggga ttggttttgg
     2941 gacgatcagg agcaaaaata gtacagcagt cttcaaaggg ctgaatggaa atatcaaagg
     3001 tgtcaatttg ctgagcgata tcaatgattt ctagcttatc cattgccaca actggtctga
     3061 taatcggagt tgaagtgact gcattaatag cctgcatgct ctctaaggtc tggcttgcaa
     3121 cctgtcctaa gctttcaccg ttaataatca ctaaagcctt tcgcttctca cgaatagcat
     3181 ctgtgatccg cagcatgaag cgtctagtaa gtgtcatcaa ataggcttcg ggtgccttat
     3241 gcttgatctc ctcttgaatc tcggtaaatg gaacctcgat aaactgtata ttacctccaa
     3301 aacgtgttaa gcgctgcgtt agatccttgg cttttcttag cgcaccagga ctggtatagg
     3361 gtgggcttgc aaaatgcact gcctcaatct caacacctcg tttcagggat agatagcccg
     3421 caaccggtga atcaatacca cctgatagca tcagcattcc ctttcctgaa gctccaaccg
     3481 gcagccctcc agctcccttt atatcttcgt gagacagata agcagcctca tcacgaattt
     3541 cgacctttag ggtaacatca ggatttttca tctgtgcctt gatatgcggc aaagcctcaa
     3601 agacggctgc tcctaaggtg tggttgaggt cgcggctatc tagctcaaac tgatggtcac
     3661 tacgcttgct ggatatttta aaggttagcc cttcgcgata caaggagctc ataatctcct
     3721 gaactgctgc tatcagtaca gggacacttt tttcaacttt atagacagga gataagccct
     3781 gaataccaaa caccggcttt aaggcttcaa tcacagacct atcatctgca ccattaagta
     3841 aaacatgggt cctgtctcga gttgatctga ctgtcacctc agaataggca gaaagaacat
     3901 cttgaatatt agcttttagc cgattaataa accgcatacg gttttttccc ttggtcgata
     3961 actccccatg acgaaccatt atttctgaat atttcatatt atctaacctt ttgtgttttt
     4021 tcataaatct gtttaaaaat cgttaaaaat tgctcaacct gtcccatatc attatcatca
     4081 tctaggctga tacggactgc tgtttgagcc aatgctgctg gaattcccat tgagactaag
     4141 gttcctgccg actttccaac ctttgatgag caggcactcg ttgttgatat ataaatctca
     4201 tgcttttcaa atgcgtgcac aataacctct ccacgaacgc cctttatacc aaaggtcaga
     4261 atatgaggag caaaatcatc tatctcagaa aagagaatgg tatcctcata ggcctgcaag
     4321 gcttgataaa taaccttttt catggctgct atccttgctt gagatctatc ctgtctttct
     4381 gtgatgatcc ttaaagcctt ggccatactt gcaatagctg ccacgttttc agttgtcgaa
     4441 cgtagctcat cttcttgacc gccaccgacc aataagggag tgattcgctt tcctgatttt
     4501 ttataaagaa agccaacacc acgaacagca tgaaatttat gaccagaaaa agaagctaag
     4561 tcaacacgcg cggttaagta agcctcaaca ggaagcttcc caatagcctg aacagcatcg
     4621 acatgaaagg taatggtggg cttatcagcc aaaagctctg atatggctgc aatcggctga
     4681 attgacccaa tctcattgtt aaccgccata atggaaacta atatggtatc ttttcggatt
     4741 aaggcagcta gctttttgac atcaacaact cccttatctg tgacaggagc ataagacagc
     4801 tcaaagcctt gactttctag ccatttggcg ctttctctga cagctgggtg ctcaatggct
     4861 gagacaatga tgtgcttacc aaagtgagat ttttcaaagg caatcccctt gatagcccaa
     4921 ttgtcgcttt ccgttccgcc agaggtaaag aaaatctctt tggcctctac atcaagtaag
     4981 gccgctattt gcctgcgcga agcctccaat atacgactgg cattggctcc tagctgatgg
     5041 agactagagg gattgccgta aatcttactg gccacttcct gatacgtttt aagtgcctct
     5101 tcgtaaggct tggtagtggc tgcattatca aaataaatca tgtgtcacct tcatttttat
     5161 tcaatacttt attgtatcac aaatttgatg aaatgaaaaa atagatcttt ttgcaggata
     5221 ggacaactct atcctagaca ataaggtaaa ccgttgactt gatttttgtt ctagattata
     5281 ctggtagatg atagagctaa gtctgaaatg cctgttagcc attaaagacc taaagcattt
     5341 gactttagct agcctatgac tcgttaaagg agatattctc atgtcatcac attattcacg
     5401 tcaacaaaag cctaaaaaat cagcaagtat tcccacaaag catattaaaa ctggctttac
     5461 cgcccttcaa aaaaccattg ccttagttgg tagtgttctg agtattgttg tagcgacaat
     5521 cactattaat cgagctctac aaccatcaaa tgagcaaccc aaaagcgatt cctctccgtc
     5581 atcaacatca acgattgtga aaattattga aaaggagtcg tcacactcaa ataaggaaga
     5641 gactgacaag acagaaacta attctgattc tagcggtact caggcgacac atactactcc
     5701 tagctcagct gatcctgcta ctaaggatac agaaaaacaa cagaataccg aaacggaagc
     5761 accggctgct aatcaaccca cagctaatga gccagctcct aacagtacaa gcaatccata
     5821 acacaaaaca cgataacagg caattcagat aagctctgaa ttgtctgcta tcgtgtttta
     5881 tcatgtgctg ttatctcatg gtaacaaact cttcagcacc tgtagggtga atggcaacag
     5941 tattgtcaaa atcagcctta gtagccccca ttttaatggc aacagcaaag ccttgaatca
     6001 tctcatcaac accataacca ataccatgca gaccaacgat ggtctcttct tctcctgcaa
     6061 cgatcaattt cattaggcag ggctggcgat gactagtaat agctgtatac atggacgtaa
     6121 attgtgattg atagacacga acagccgctt gcccataggc ttgaatagct gcctcttctg
     6181 ttaagccgat cgagccaatt ggcggatggc taaagacaac tgtcgcaacc ttgttataat
     6241 caagcttttc attgggctta ttatgaaaca agcgctctgc caagcgacga cctgctgcga
     6301 cagcgactgg ggtcaaagca agctttccat taacatcacc aacagcatag atgccatcaa
     6361 cagatgtgtt ttcataagcg tcaacagcaa tatagccctt cttatccagc tcaactcctg
     6421 tatgctccaa gccaaagcct gtcacatttg gcttgcggcc aattgcccaa atcacttggt
     6481 ccacttcaag cctacgacca tcggacaaat gcacttgaag agagccatca ttagccttgg
     6541 taaccttagt aacatcggca ttggtatgca gccttggtcc agataccttc atctcatcga
     6601 ccagaacctg gataatatcc tgatcaaagg tcctcagtgg cctgtcatag cgaaccagca
     6661 aatccgtctg agaacctagg gcattgagca ctcctgcaat ctcaacagca atatagccag
     6721 caccgacaac tgctgttcgt tttggaatat catctaaagc aaagaaacca tctgagctaa
     6781 tccccagctc agctccttca atgtcaggaa aaataggctg accaccagta gcgattaaaa
     6841 tatggggggc tgtataggtc ttacctgcaa tgtcaaccgt atgctgatca ataaatcgtg
     6901 cataatcata aatacgatca accccgttat gctcaaagcc cttctcataa gaggcatgaa
     6961 tacgatcaat ataggcctga cgattgcttt ttaaggtttt aaaatcaaac ctatcctcta
     7021 acaccgtaaa cccgtaatcc ttcgcatagg tatgaatcgt ttctgctacc tgtgcgccat
     7081 accacatgac ctttttaggc acgcagccca aattaacaca ggtccctcca atagccttgc
     7141 cctcagctaa taggacctta gcaccgtaca ttgctgcacg attcgccgag gcaatcccag
     7201 cgctcccacc accaatcaca atataatcat actgaattgc cattaattta ccacctttac
     7261 tcttaatgct tgcctcaata gatttgttat taagctatca ttattgcttt attttaatct
     7321 actgtcattt gactataaca taaaataact tgtgtctcaa atccctgcta cgacaaaaaa
     7381 agattgtgat aagcatcaac aatcctttct tctcttaatc ctaagccagc ttagctctac
     7441 ttggccaaat ccttcaatgg tgcaaataca atccgttcaa tatcattaac atagacggaa
     7501 agagcctgct gagcgttaaa ataccctttt aataggtcat tggcctcaat tttttggctg
     7561 agagcctgaa tatctgcctg ctctgtctct gttggcagct gaccggtctg catgagtcct
     7621 tgcaattttt cttgcacagc aacaaactca tcaaatagct gactggcagc ctcatctgcc
     7681 ttaatctctt ctctggcttc caaggccttg cgatactctg ggagcgcacg aacagctcgc
     7741 tcaagcttat tggcataatc ataaatatct tgggacatct ggatctcctt ttatcattta
     7801 ttatccttat catatcacaa tatcaagcca tttgtcgctt aaaaatgatg aacatagtca
     7861 cgataggcaa aaaaagcctg ctttaaatcg gtcatattgt ctgatggaaa ttgttccaaa
     7921 atctcttttg tgatgacagt tgctacaaca ttttccatca cgacaccggc agccggcaga
     7981 gccgtaggat cagaacgctc aacagtagcc ttgtaaggct cgtgcgtctc agtatccaca
     8041 gacattaggg gcttgtagag ggtgggaatc ggcttcatca cccctttgac aacaataggc
     8101 tgaccagtag tcatacctgc ctcaaagcca cctagtcggt ttgttcgacg actgtagccg
     8161 cttgtctcat gccaaatgat gtcgtccatg acctgcgagc ctttttggta gcccatgtca
     8221 aagcccatac caaattcgac ccctttaaag gcgttgatag acaggacagc ctgcgcgatt
     8281 ttggcgtcta atttacgatc ccactgaaca tatgaaccta agcctgctgg taagccatga
     8341 atgagtgttt caataatacc accaagcgta tctccttctt ttttgacttg atcaatatgg
     8401 gccttgatag tcgcctcttg cttgggattg acaatagata aatcagaaga ctctgctact
     8461 tttttgatat ctgcaaagga catcgcctca ggcacagcta cctcgatacc accaaaaact
     8521 aggacatgat tagcagtttc gatcccaagc tcagtaagga ttgccttagc aattgcacca
     8581 acggccacac gcatcgctgt ttctctggca gaggagcgct caagcgcatt tcttaaatca
     8641 tcaaaacgat atttgatccc cccaaccaag tcagcatgac cagggcgtgg acgagtgatt
     8701 ttacgcttga acttgatttg ctcttcaaca gcctcaacag ccataatgtc tagccatttt
     8761 tgatggtcct tgttttgaat ggttaaagta attggtgctc ctgttgtttt gccatgacga
     8821 acacctgaag agatatgcac acgatctgat tcaatgcgca tgcgtgcgcc acgaccatat
     8881 cccccctgcc gacgcttcag ttccttgtta ataagctcag ctgataatgc taagcctgca
     8941 ggaattccct ctataatggc cgtcaaagct tgtccatgtg actcacctgc tgttaaatac
     9001 ctcattattc ctccatttat caatcataga cataaaaagc aaacctgccc tcctctagac
     9061 aactaaaaga cattattcta agctatccaa gagaataatg tctgttaccg tatcttatca
     9121 atcctcagat tccaaaacat gaagaatcct tttcatatca gccaaggaaa cctgccctgg
     9181 tgcactggct tgatctaagg acacaaaagt ccacgaggac cctacaacat cacctgccaa
     9241 gcgtgatagt ctgcctagct ttcccattga catggttgca aattcctgct ctgggttaag
     9301 tgttttaaag cctctggtat aattcatcaa atccaaaacg tcctgctcgc tctgtggcat
     9361 gacagcaatc ttgacaacgc gaggagctag cttagtcatc tccgaaaaag cctccatcag
     9421 attttcaggc gtctcatcaa aattgtgata agacaagaca agattcggaa agtcaagcat
     9481 ttcatgaaag acagccttgt gactaaagta ttcaaagtca atatagtcag gattataaat
     9541 cgcattgatc tccttgatca aatcaacgta ttcctgatca gaaagtgtaa tatgccctcc
     9601 ttcttgactt gtacgaaggg taaaaataat ctctctacct gcaaattttt caaaaatagc
     9661 tggcgctaca gaaacaatat cctccttagg aagaaagtct gctcgccact cgattaaatt
     9721 aacatcttga tatttagaaa cgtcgataga ttgagcctct tcaacatttc ttggcatgac
     9781 tggtgctaca attttcattc tcgtaccctt atagtaaata cctttaaata attacttctt
     9841 tcatctgctt tattgatagt aaaatcactt ggaagctgct caagtgtcat ctgagctaat
     9901 ggcctgcctc ccaatccttt gataatttgc tttttaaact ggttaacagt catattggca
     9961 gcatttgttg aagcgataat tgttcccttg ggggccaata ggtctagagc ctcagcgatt
    10021 aattgatggt aatccttact cactgaaaac gtctgctttt tgtttctggc aaagcttggt
    10081 ggatcaataa taataagatc aaaagaaagt tgctttcgct tagcatactt aaaatagtca
    10141 aaaacgtcca taaccacaag ctgatgactg gataggtcca actgattttg aacaaaatga
    10201 gcctttgata actctctgga gcgctttgcc aaatcaacag aggttgtctc aactgcaccg
    10261 cccattgctg cagctacaga aaaagctgct gtatatgaga acaggtttaa aacagtcttt
    10321 ccaagcgcca agccgtccac cagacctcgt ctaacctcat gctgatcaag aaaaatccct
    10381 gtcatcaagc catcatttaa aaatacctga taggctacgc cattttctaa aatggtaaag
    10441 gtatcaggag caaacgcgcc atacaaatga gccgtctcct tatctggtcc cttaaagcga
    10501 atcttttcat aagctcccct gacctcagga aaaacctctc gaaaagcctg aataataagc
    10561 tccttttctt gataaacaaa gacattatac caagaaaata aagcaaagtc cttatagagg
    10621 tctatggtta gtcctccaaa atcatcaccg tcttggttaa aaagacggta agcatttgtc
    10681 cattcagacg cggcaaaatg ctctcttttc ttcttagctg tcttaaataa ggtcacaaaa
    10741 taagaaaccg acaatttctt aacagacctt cctagatacc agcctactcc cttatgttgc
    10801 tttgaaaggt aagctgtgcc gatgagctga tgagatgaat tcacaagctg cactaactgg
    10861 tagtcccaaa tggtgccatc aaaatccttt tcatctagta attgtatccc tgctgctatc
    10921 ttgcgttcaa caaggggatt aatacagacc ttattcatag tttctattat aacaaaaact
    10981 a
//
LOCUS       DARYVE010000065        10698 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYVE010000065 DARYVE010000000
VERSION     DARYVE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10698
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..309
                     /locus_tag="TVW25_001658"
     CDS             <1..309
                     /locus_tag="TVW25_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379272.1"
                     /translation="QEGNIIAAEQLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIF
                     NDVQILTDLSSLRAYIVLFNYTKKLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN
                     "
     gene            745..1164
                     /locus_tag="TVW25_001659"
     CDS             745..1164
                     /locus_tag="TVW25_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1379273.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            1165..1488
                     /locus_tag="TVW25_001660"
     CDS             1165..1488
                     /locus_tag="TVW25_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379274.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            1747..2376
                     /locus_tag="TVW25_001661"
     CDS             1747..2376
                     /locus_tag="TVW25_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379275.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            2358..2780
                     /locus_tag="TVW25_001662"
     CDS             2358..2780
                     /locus_tag="TVW25_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379276.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            3039..3443
                     /locus_tag="TVW25_001663"
     CDS             3039..3443
                     /locus_tag="TVW25_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379277.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            3440..3868
                     /locus_tag="TVW25_001664"
     CDS             3440..3868
                     /locus_tag="TVW25_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379278.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            3861..4274
                     /locus_tag="TVW25_001665"
     CDS             3861..4274
                     /locus_tag="TVW25_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379279.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            4537..4929
                     /locus_tag="TVW25_001666"
     CDS             4537..4929
                     /locus_tag="TVW25_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1379280.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            4930..5253
                     /locus_tag="TVW25_001667"
     CDS             4930..5253
                     /locus_tag="TVW25_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379281.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            5566..6036
                     /locus_tag="TVW25_001668"
     CDS             5566..6036
                     /locus_tag="TVW25_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1379282.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            6020..7113
                     /locus_tag="TVW25_001669"
                     /pseudo
     CDS             6020..7113
                     /locus_tag="TVW25_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(7407..10553)
                     /locus_tag="TVW25_001670"
     CDS             complement(7407..10553)
                     /locus_tag="TVW25_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379283.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         3353 a         1826 c         2326 g         3193 t
ORIGIN      
        1 caggaaggaa atattatagc agctgagcag ttgctctcag aaaaattgga tcctactctt
       61 ttttcattag ggtctgtgga aaaagataaa ttaacccttg taaaagaaaa taatgcctat
      121 agtttaatat ttaatgatgt gcaaattcta actgatttaa gttcattacg tgcttacatt
      181 gttttattta attacactaa aaaacttgag agagcaaaag aattatatgc tagagcacta
      241 catgacttgc ctgattgtaa gttagaattt aatcagtttg tagaatatta tttgatagga
      301 aggaattaat aaaagaacta ttgaaatacc atatggcatt ttgagttcag atgcccagtc
      361 atggcaggag gcagcgaaca agatgctcag cgagctacat tagtaggcaa tatcctagga
      421 ggattcgccg cctcaagcgt cgccagacgg ttcagcttga atgagccaat agcagctagg
      481 gtgacgaaac cgacctacag ccgccggcag cttttgaaga accttgagaa cagcaggctg
      541 gcaagagaaa gctcgaggtt tgatgattat cttcgaagag aataccggtt aaagggaagg
      601 tattttgcag aaagaaccac tatttcaaat ggaaagatag gttatctttc atctgactat
      661 tttgaaggca agcaaattcc ggttcgctct agagcttttg ttgacgaagc aggccatatt
      721 aaatggccaa atgccgatgg ctttatggtg gataatttag gtaatcctat aacggagcag
      781 gtcactctca aagcaggtca aatcattgat cgatatggat caagtagtgg tcgatttacc
      841 agtccgatag aaaatggggt gacattacca tttaataaac gtggattacc ctacccagaa
      901 ggatatcaag actattataa gtacgaatta gtaatggatt tgacgaagaa aaatattgtt
      961 aatgcgtatt atcaatctga agagattata agaaaacaaa tatctgtaga aatgaaaaaa
     1021 tggaatcttt cctttgatga tttagctaat attcagaagg gtgagattac caaagtattt
     1081 gggcaaggtg gaggaattca gattaaattt ccgacaggtg ttggtattta caagaaaatg
     1141 ggtttattaa aggagattaa ctagatggat aatacaaata tattgaattg gaaaaaagat
     1201 attgaagaag caattaaaaa tcgaggtttt gagagtttac attatgtttt atttgatgaa
     1261 gaaaagcgac ttccttgggc atttcatctt tatcaaaaaa atggaaaatt ctatgttgaa
     1321 ggaagagatg agcgatcata tatcattggt catagcaggg aatatcgtaa atttgatgat
     1381 gccaagcatg aattgcttaa aaaattagaa ttagttatag aatctaatcg gttaaaaaag
     1441 cagttaggtg aacctacaga atatccctca ccactatgga atgaatgagt ttcatgtatt
     1501 gtatgccatg gcaccaagct tttaggaggc agcgagcaag acgcccaaag agcaacatta
     1561 gttgggaata tcctaggagg acttgccgcc tcaagcgccg ctagaaggtt cagcttgaat
     1621 gagccaatag caactagggt gacgaaaccg acccacaacc gccagcagct tttgaagaac
     1681 cttgagaaca gcagactggc aagagaaagc tcaaggttta agaattatgt agcaagagaa
     1741 aaattcatga caacccttgc aggcatgagt cctgaggata gtcagcgcta tattcaatgg
     1801 cacaaatacg caaaggctgg acttagtccg tcagatcgag taaggattct agaaatatct
     1861 gagaaggcac cgaagataga gtatcttccg ggaaaaacat cagatagtat attggcaata
     1921 tccaagggtg atcgtccaaa tgtggagaaa gtctacagtc cagattatat tggatttcat
     1981 agaaaacaat ttgataacgg tgcaactaga tttcagaaat ttaagcccaa tgtagattac
     2041 caagacggtt tagttggtga cgatttaggc aatagttttt ggttaagtac caaggacgcg
     2101 gatattatcc aggagatagg aaagggaaat aaccgtcttt atgagacact cttaggcttt
     2161 gatgaagggt atttagaaga tggtcccctc tatcgcttag atgtttcacc agaagttgtt
     2221 tcacaaaaag gtgtttcaat accaagtggt aatgaaaaag gggcaaatag ctggtggcgt
     2281 cctggaggtc gtacttatcc ggggaatata ccagagggag ttatgcaagg tatcagtaca
     2341 aagaaaggag atcacacatg gcacgcagtc aattagagtg ggaagatgtt agtcaatatg
     2401 aggaggtaaa gggctatggt caaagggtgt ggaagcatca agggaaatat tactttgttg
     2461 ccgaagaagg tggcattgct gttcaacgag tagtatatga gttaccgtat gacttatttg
     2521 aattgttgga aagtggagaa cgtagtcttg gagatgttca ttcaaagcta caagatggta
     2581 attggccacc aacagaagag gaaaagaagc aaagtcatag aaaatttgtt attgacacac
     2641 caactgcgct gattgcagac cctactagtg tgtctctgtt ctcagaagaa gaattatcaa
     2701 aattagtgcc aatcgctgaa caacagtgga tagattggaa gggaaagctg ccagatgatt
     2761 atgtcagtcc tttgaaataa tgtttaagat agcggagccg agattagctc tgctatttta
     2821 aagcatgttc ttaataatta gcctgcgaca gcttatcagg gagtagctcg tcaccttgaa
     2881 gccaatgcca agcgtctcca agcgccgcca gaaggttcag cttgaatgag ccgatagcag
     2941 ctaaagtgac gaaatcagcg aaaataaccc tttctgaaaa ggtactagac acaaaggttc
     3001 ggtttgatga gtctcgcatt gtggcttacg cagaaagtat gagtaagaac tatacagaag
     3061 ctgacgtggc caaattaacc gagctgacca cccacaatgc aaaaaccaaa acagctttgc
     3121 tgggatatta cgaagcaaac agcgttactt cgtatgaaca aattgcacat caaaataagt
     3181 taacttactt tgatgccgga agtgatggtt ggaatgcgat gtcgagagtg gattctaagc
     3241 tagctcaaag ggttaatcgt gaatttttga taaaacaaat tgagaaaaga aaaacattta
     3301 tattaacgtc taatccatat actgctcaat caatcgcaga tgttagtggt atcgggaagt
     3361 cttatgctaa agaaattcag attttagcag aaaatggata taatattgaa aaatttgaaa
     3421 ggttttggag ggcatataaa tgagtgaaga acagtattta ccagtaaagg aaagcttagg
     3481 atatcgtaac ttaaaaatag ctttaatgaa tgttttttca atagatttgg ataagtttac
     3541 aattattgaa ggagaatttg aaaattttgg ttttcattta aattataaca ataaagaaat
     3601 cataatctgg attacatcaa ctggtaagaa tagacaattt gaatatggag aaggaggaca
     3661 attgatgatt tcacttccta atccaaagta tcctgataga tcctttcttg atagggtaac
     3721 cttagaaagt cttttaacag acaccgaaaa aatagaagca gttgactatg cttttggaag
     3781 atacgagcat cgtctcgaaa tagcgttggc cattctaaaa gattatttag attcagacga
     3841 agcaaaggtt ttattgaaaa atgagtgagc aatatttatc aataaaagaa agcttaggtt
     3901 ataagaacgt taaacaggct ttatggacta ttttttcagc caaccttgat gaaatttcta
     3961 tacatgaagg agaagatgag aattttaact ttgtctttac atataaaaat tgtgaaatga
     4021 tgatgggaat ttatgatact ggtaagaata ttcaattcca agctggagaa ggtggtttat
     4081 tcagtgtaag tttacctaat cctaaatatc cggagcagtc atttcaaaaa attgtatcac
     4141 tttcttattt aatttctgat aaaaatgtaa gtgaaaatat aagatggtgc ttaggactgg
     4201 atctgaaatc tgttgaatat gttatgcgtg ttttgaagga ttatctggat caaaaatgtg
     4261 aagaggaaca ataattctaa tcacttctgg agggcatata gatgagtgaa gaacagtatt
     4321 taccaatacc ttcgaagaga ataccagtta aagggaaggt attttgcaga aagaatcacc
     4381 atgccagatg gaaaatatgc ttatctgtcc aatgacattg ataaagctac cggaacacca
     4441 attcctgtcc gatatagaaa ttaccttaag gctgatggtt ctattaattg gccaaactat
     4501 aatggcttta gtcttgatgt aaagggaagg cctatcatga ctccagcttt cctaaaaaca
     4561 ggtgatttac ttgatagata tggagaatct ggaggaacat tcacaagtcc aatcgttgac
     4621 cgtaaggtta taccatttaa caagcgaggc ttaccatacc cagaggacta tcaaaattat
     4681 catcaatata aggttcttaa ggatattaat atggaaaatg ttgaaaaggg ttaccataat
     4741 ttatctgata gtagaaaaaa agagttaaat ctattaatga atagatttga tttttcactg
     4801 gtagacatag caactccaca aaaaggaatg attgatcttg tctttggctc tggtggaggt
     4861 atccaaataa agttaggaac ttctgtaagt tggtatgaaa aattgggttt aattaaggag
     4921 ataaagtaga tgaaaaattt agatcatcaa aaggcagaac tattagaagc agtccatcaa
     4981 ttaggttatg atagtctaag gtattccatt ttttctaaag agagaccagg agaatgggaa
     5041 actgtcattg aatatgataa tagtcaaggc ttatatgttg tgtatgcaac tatggataga
     5101 gctagttata ataagaaatt aacatttgaa acatttcaag aggctaaaga aaaatttctt
     5161 gaaaaacttc ggttagatat ccaaatcaac aggtactatg tggaagaggg catgcctgta
     5221 aattacgatt ctcctttgtg gtcaaaaaat taatacaagt aaaggagaat atacatggca
     5281 tgtagtcaat tagagtggga agataaatga aataatggtc ctaggaaatg tcccgactgg
     5341 aaactatctt atgaactctt ttatggaaaa gtgttgcact taatttgaat tttgtcatat
     5401 aaaaaagccc tataatctcc atggtggact tacccactac agaaatgata gagctaaaaa
     5461 tctccatttg gggatttttt tgtaaccaaa tgaagcagtc gttcgttata taggtgaaga
     5521 agggagggga gaattatcag gctagatgct tatgaaagag agctagtggc ttattctaag
     5581 gaaattattg cctacctagt gagatcaggt gttgctaagg agctagcgcg tgatattagt
     5641 caagacgttt tgttaaaaat gcttgagagt gaccttgctc tgcctcctga aaaaatacgt
     5701 gcctggatgt atcgggttgc tgttagaaaa tacattgacc gatataggcg ggataaggct
     5761 tacttggata ttctccaaag ggattttttt catcaagaaa gggttgttga atttgaccac
     5821 cccaattatg agccgcttta tacagcagtc aatgaattgc cagaaaaata ccgctgggtc
     5881 ttgtcgtttt attactttca ggacctatca gtcaaggaaa tggcgtctct gctccattgg
     5941 tcagttagca gcgtcaaggt caacttgatg cggggaagac gatgccttaa agaaaaacta
     6001 aagaaagcag gttataccta tgacgatttc aactgatttt gaagccattg ctaagcgcca
     6061 taaaaggagg ctgaccctta aatatgtagt gctgagtgct ggcttagcct tagtagctct
     6121 tgtactgggc tatatgggat taaatcgatt gacaagcatg aacggtcagt atttaatggc
     6181 ttattacaac aatcgtatac aaattgctta tcccaatatt gatgttaata gcttctttta
     6241 caatgccaat tcgcagttta ctggtgagct tcattctgag cggaccaagg atattgctgg
     6301 gatttcggta ccgtttgagc cctatagagc tccttattcc ttgcctttac ccagagagag
     6361 atggactata ccaatgaata ccttgtttca ggtgatgatg gacggtcaac ctacacaaga
     6421 ggtacacatt ataaaatgcc tcgcttcttc aacactaagg ccaagatcac agaaagcaac
     6481 tatgacaagc caacgcagga cctagacttt attgctgaca tgtcaggaca ggcgattgag
     6541 gtagccatta cctttgataa gccttattta ttatcggaca tagtcaagct ggttccagac
     6601 cagctaaagc tgaattggat ctggattggc acagaaagca gctatgacac ctcagggctt
     6661 ttccctgcta atttatatgg ctttaagcca aactggaagg ctaatatgac gtacaaggag
     6721 caaaagcagt tagataaaaa aataaacgat atcctaaaaa aggacagcga ggctgatttg
     6781 tctaagctta atgctgctta cgataagcca gtcagtccaa cggtggctct gcaaaattcc
     6841 tatgatacct tcaggcacta tctacaagag gcagctgaca atcattggat taatagtacc
     6901 tatggcggcg ctaatggatc tcatttaagt gagcaggagg atgtggcctt atttctaaaa
     6961 aacaatcgca atgtcaaaac agctaagttt gctggcatta ttttaaccgg caaggctgag
     7021 cagtttgcct ccttaaaaac agctgattgg atttatgcct caaatattgg tcagtctgtt
     7081 gccattcagc cctatcatca gctaaccaag taaataaaaa gcttgtgctg ctaatcaagc
     7141 gcatcaggca aaggataaaa agcctaaaag agattagatt aagtaaatcg atgcttaaaa
     7201 aagctccagc ttaggtcaaa agacgtcaaa aggctcttgg aggtcagtgt ttgatcactg
     7261 cttctggggc tttttgcttt gctgcaatca aaaaagcttg aagcagctct ctcaattgag
     7321 catgtccttc aagctgagac tcttatattt tatagtattt gtaagtatag ttttagctag
     7381 ccttctttta agcccaaggg cttagcttac tgtttagtat ctttttctaa attattgata
     7441 ataactggat aatccttcaa tgcagacttc atgtcattta gagtgctttg atatgctgtt
     7501 tggtctgagg ctaccaatgc tagcttgtca ttccatgctt tatagtttaa tggctctgcc
     7561 tttagagcag catctaaatg attaagctta gtctccttgt cagtagctgc ttcagcctta
     7621 tatcgttcat attctgaggc attataagcg tctatattaa gagagtagac gttatgaatt
     7681 tggacataag gaagtgttgt gttgtagtta ccacagcctg tccagcctga gacatcatag
     7741 ccgagctgat aggtatggtc agcatttaag tagatataag cacagtgacc tggttgtcca
     7801 ataggaaagg ctggtacacc ataagcctgt gctagcacac tacttaattt agacatagca
     7861 ccgcagacac caccatattt gatgacttcc ttgatggttg gatttggtcc gtaaaagcca
     7921 gagctttgga cgctcacacc tgtttctggg ttggtcatga catagctgat cagtgaatag
     7981 cccttagtaa tatcattacg gttaatcata gcaggcttat tggtttcaac gtattgtctt
     8041 aaccatttca tgtcctcatc agtaatttta gcattgacga catttcggat ttgctcaaca
     8101 gttaagctgt aaaaatcttc aaataggata ttgccctgct cagcctctgc aaaggttgca
     8161 aatctttcaa gtggatcaat cttgcggctt tcattgtacc aagcacctac aggcttgtta
     8221 aattccaagg caaccgcaat ggccattttg agctgaatac cttgatgtga ggtttcgtat
     8281 ttatcccaaa tcttaaacca caattccaat gcttctagct cattggtgag gttataggtg
     8341 tttttgaatt ggtatgatga catgccaccc tgtgctgcag aatgggcata gcctgcacca
     8401 agatataatt gcattgcttc attatctttg agcaaccaat caataaaggc tttatgcttg
     8461 tcgtcttgct tcttgaagtc ctcgattttt tccttggtta gtcttttttc aacggcttgt
     8521 acgagtgtat tagtagcttt agcctctagt gcaaatacag aagccaaacc acccttggtg
     8581 attcgaatct ctgccttatt tttagggagg ctaagagaaa cagccttgtt ttcttcatca
     8641 taggctttga ctctagtatg gtgctcacta ccagttaggc ggatcttgta gcccaccttg
     8701 aagggaatag tctctgtttt ggctgttaga gcttggtttc caataaagtc ttgtgtgtag
     8761 acaaccttgt cttttaggtc taagacctca agcttttcgt aagtcccact gaagtaaaca
     8821 tgtggcttag cctttttggt tttgagagtt aaggtagagg cattgtagtc aacctttaag
     8881 gttgcgtatt ctgcattgcc taagccaagg aagcgcagcg ttctattact atcatcaata
     8941 cgctcaagct gcccgtttct caccacataa gtgtaagggt tggtattgtt ttgctttaga
     9001 gcgtcattgt ggttagtgta gaagcggtta ggctcctgct tagtgatgac taggtaatag
     9061 ccttccttga gagtaaggct ttctgtttta gctgtttggg aaacattacc cacgtattcc
     9121 ttagcataaa cggtttcttt tttctcattg agaatggtta gggtagcgta attgttagcg
     9181 atgtaagagt gaggctgtcc ttttttagtg actaagcttg cagtgtaact gccgtcagca
     9241 tagaagtaga gctgagcaaa tataccattt cctagccctt gtagagtaaa ttgctgtagc
     9301 aggctagctg ccttatcaag taaacttagg atttgctctt tttcaggctc tgttgagtca
     9361 gtcgcctttt tcctaagagc atctattttt tcttgtgtga caccacttgc tagcttactt
     9421 gtagactcat ctgtaaatag agtcagtacc tcagactcaa gctctgagcc tgttttagac
     9481 ctcattagct ctagtgagtg gtcaagaagc tttaaggttg cttgattttt agagagtgtt
     9541 aatggcgctt ctaccgcata atcatcgtag aatttcactc tggtatggtg ctcactacct
     9601 gtcaagcgga tcttgtagcc tactttaaaa ggaatagtct ctgttttagc ttcgaggact
     9661 tgagttccaa taaagtcctt tgtgtagatt acttgatttt ctgtatccag cacctcaagc
     9721 ttttcataag atccactgaa gtaaacatgt ggcttggtct gcttggtttt gagggttagg
     9781 gtagaggcat tgtaatcaac ccttaaggtt gcatactctg cattgcctaa gccaaggaag
     9841 cgcagcgttc tattactatc atcaatacgc tcaagctgcc catctctcac cacataagta
     9901 taagggttgg tattgttttg ctttagagcg tcattatggt tagtgtagaa gcggttaggc
     9961 tcctgtttat tgatgatgag gtaatagcct tcttttagct caagctcttc tgtttgtgct
    10021 acctgagaaa cattgccggc gtattctttt gaatagacgg tttccttctt gttattaaga
    10081 atggttatcg tagcgtaatt agtagagaaa taagagtgag gctggcccct tttagtgacc
    10141 aaacttgcag tgtagctgcc atcagcatag aagtaaagtt gagcaaagac accattgcct
    10201 aacccttgta gggtaaactg ctgtaatagg ctagctgcct tatctagtag acctaggatt
    10261 tgctcttttt caggctctgt tgagtcagtc gccttttgct ttaaggtatc tattttttct
    10321 tgtgtgacac cacttgccag cttactgcag gagttatctg taaataaggc ttgggtatca
    10381 gtcatcagtt gtgatagctt agcctcggca gaaggagcag ctgtatcacc tgcattaact
    10441 gtagcggcta ttccatcaga agtatcagta gttgcataaa caattgctgg agagagctga
    10501 tgtaatgtta atattccaac acatgctagt gctattattt tctttagttt catcgttata
    10561 aagtcctttt acaataaaat aaagtgattc aaaactctgg gaaaagaata gctagcctta
    10621 aaactatact cgcaaatact ataaaataga aagactattt accctcctta gctcttgatg
    10681 ctgtggtgat gatattgt
//
LOCUS       DARYVE010000066        10564 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYVE010000066 DARYVE010000000
VERSION     DARYVE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10564
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TVW25_001671"
     CDS             complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TVW25_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1379284.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1719..2432)
                     /locus_tag="TVW25_001672"
     CDS             complement(1719..2432)
                     /locus_tag="TVW25_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1379285.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2453..3100)
                     /locus_tag="TVW25_001673"
     CDS             complement(2453..3100)
                     /locus_tag="TVW25_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1379286.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TVW25_001674"
     CDS             complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TVW25_001674"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1379287.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TVW25_001675"
     CDS             complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TVW25_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1379288.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6539..7321)
                     /locus_tag="TVW25_001676"
     CDS             complement(6539..7321)
                     /locus_tag="TVW25_001676"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1379289.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TVW25_001677"
     CDS             complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TVW25_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1379290.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8749..9381)
                     /locus_tag="TVW25_001678"
                     /pseudo
     CDS             complement(8749..9381)
                     /locus_tag="TVW25_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9383..10150)
                     /locus_tag="TVW25_001679"
     CDS             complement(9383..10150)
                     /locus_tag="TVW25_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1379291.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQDIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10432..10564)
                     /locus_tag="TVW25_001680"
                     /pseudo
     CDS             complement(10432..10564)
                     /locus_tag="TVW25_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3119 a         2382 c         1936 g         3127 t
ORIGIN      
        1 gattataccg ttaaataagc tgccagatca gctaaggcac gtttagcgat agcttcatag
       61 cgttcctttt tatctctgat acgaggtccg tcaagctctt taataatacc aaaattgaca
      121 ttcattggtt gaaaatgctt gctgtccgcg tgtgtaatat aataaggcag gctgccaatt
      181 gctgttgtat ttggaaaaac aagtggctct tcttccttga atagccgagc agcattaatg
      241 ccagccacaa gtccagaagc tgctgactcg acatagccct ccacaccggt catctgacct
      301 gcaaagaaaa gcctgtgatt agcgcgtgat tggaagcctt gtgtcagaag ctttggtgaa
      361 tccatatagg aattacggtg catcacaccg taacgcacaa actcagcatg ctcaaggcct
      421 ggaatcattt ggaaaacccg cttttgctct ccccatttta aatgtgtctg aaagcccacg
      481 atattataaa ggctgcctgc agcattatcc tgacgcagct gcacaacagc atagggcgtc
      541 ttgaaatcac cgtcacgtgg tcccttgtaa tcatctggat attccaagcc aaccggcttc
      601 attggaccat aaagcatagt cttaatccca cgctttgcca taacctcaat tggcatacag
      661 ccttcaaaat acttttcctt ttcaaaagca tttaaaggag cttcctctgc tgttgtcaaa
      721 gcctcgtgaa aggccataaa ctcttccttg gtcattggac agttcagata agcagcttct
      781 cccttatcat atcgcgattt taaataaacc ctatccatgt taatggttga cttatcgaca
      841 attggagctg ctgcgtcgta aaaataaaag ccagcaccac catttaaggc atgtattttt
      901 tcagcaaggc tgtcactggt caaggggcca gttgcaatta ctgtaatagc atcgctagga
      961 atgtcaataa cctcctcacg aatgatttca atcagagggt gattttcaag ctcagctgta
     1021 acagccttgg catagccttc gcgatctaca gccattgctc ctccggcagg gacacgatgg
     1081 gcttcgccag cacgcataat aatcgaatcc agacgacgca gctcttcctt taaaagccct
     1141 actgcgttgg ttaagctgtc accacgaaaa gagttggagc aaaccaattc tgcaaaatgg
     1201 gtggttttgt gttgcggtgt tgccttgaca ccacgcatct catatagctt aacaggaata
     1261 ccacgcttag caatttgata agctgcctct gatccagcta gaccagcacc aataacatta
     1321 atataagatt gagacaatag accaatacct ctttggggac ttatccatca ctgattgccc
     1381 cgcaactctt tctttcaagt aattaccctg cctattataa cagaaataag agcaaagcaa
     1441 aagaaggagc tgaacagcct cagtctttta tataaaggag ataagcccgt acctgcacgc
     1501 tctccacaaa gctagctgct tcaagcattt tagctttcgc ccaataccag ctatccacat
     1561 atcttgttca ctgcagtagt tactggaagg ctttttaagg cttatttttc aaaatctagc
     1621 caaaaatatt tcaccggacc tcatcatctt gctggtagca gctaaacaag ccttttccag
     1681 taaaaaaaaa gcaagcgaaa gcctgccctt gttcttgttt agaaaaaaca catccatgct
     1741 gcgataaaga cacttaagac actaaacagc gatccaatca aataatattc agcaaaggct
     1801 gggctttcag agattttatt gtagcgagca atagacttag cggtaagcac cagtccgatt
     1861 gaagcaaatt gtcccaacac catacaaacg cccataacaa tacgctctaa attaccaata
     1921 gccgcacccg cccctacaat ggtatccatt ggtttatcac tagctggctg gaatttattg
     1981 aagcagagct taaagataat attgacaggc ttggtgatca aaaccataaa aagcactaac
     2041 aataactgcc gagcatgtaa ccaatcaggg atctcagcct gattaacacg agcgactaaa
     2101 gccagaataa tgaaaagatg caagagctgg tccaacacaa agacccacga ccgatcaagc
     2161 ttaatgatac gagcccattt tggcttaaaa taatcaataa ccgcatggct actaaaaata
     2221 aggatcgctg ttagccaaag cttaggtata cacatcacca ctagaaacaa tggagcagct
     2281 acccctaata agtgcagccc cagataagca agctgctcct ccttcttatc agcaataacc
     2341 tgactctgaa ggtgataatc tgataaaaaa tgacaaatca ctagcagcac taaaatagga
     2401 tgctgataaa ggtaatcaga taagccctgc ataggtggct cctttcctct ttttattctt
     2461 gtaggtaggt caaagctgca tggcgacttc taagataaac ctttacactg ctgcttttta
     2521 agcgctttga caaggcactt gattggaggt ccaatgtatc gccaatgagc tgttggtcaa
     2581 attgttcttc atagatccct aagtctaaaa gcgcatgaaa cacctctaat tgactagcac
     2641 gccagctagc ttttatcgcc tcaccagctg ctaaaaggct attgagcacc agatccttgt
     2701 gctccttatc agtccgtata gctacctggg tattgccata atcatttttt tgatgaatgt
     2761 aatgaatagc ctctctggca cgccaatagg ctggaccgtc agcaccaata ctaatatcag
     2821 ggttaatatc agtcaaaata gtcccctgtc caataccaaa cctaacaggg tagcctgtca
     2881 tggcttgatt aattaaatca atgagttgaa aaacaggcgc atcattagtc aacaagcctt
     2941 gaaattcatc acccagagtc acagataagt tagagacgat ataggaagaa aaatcatggt
     3001 tgagctgatc cagacaggcc tttaaggact cttgcaccaa agaacgcgac tgaatttgct
     3061 tagaatggac caaatcccca ataacagcga tatatagcat gattttccct ccttttatga
     3121 cttccattat aacagacaaa aaccaaaaag tccattataa tggaaaatca tctatatttc
     3181 cgttataatg gacctctgct aaaatagttc aaacctactt tacaatctct tctttatagt
     3241 cacagacttc attgctacac acaacctgct tacctccacg aatttttttc tcaacaaggt
     3301 aatcgcctga cttcggacaa gaccgtccta ccggcaaatc ccacgaggta aagtcacact
     3361 cagggtagcg gtcgcagcca tagaaaatac ggttacgctt tgttttgcgc tcaatgactt
     3421 ggccttgctg acaagctgga caagaaactc caatttcctt tgtgatggcc tttgtatgat
     3481 ggcactcagg aaagttacta caagcataaa acttgccaaa tctacccagc ttaacaacca
     3541 tcgggtggcc gcacagctca caatcaaaac cagccggctc gtccttgatt tgaatttttt
     3601 cgatctccgt ttcagccttg gttaactcct taacaaatgg cttgtagaat tggtcaatca
     3661 cattctgcca ggcttctttg ccgatctcta tctgatcaag cttatcttcc atatcagctg
     3721 taaatttgac atcaacaata tcagggaaga attccacaat caattgatta acaatttcgc
     3781 ctaattccgt cggctcaaag cgtttagcag ccagcttaac ataataacga cgctgaatca
     3841 catcgagtgt tggagcatag gttgatggcc ttccaacacc gttttcttcc agtgttttaa
     3901 tcaggcttgc ttctgaataa cgagctggcg gttgagtaaa gtgctgttca ggtgttaagg
     3961 taaccttttt aaccacttct ccttctgtca tttcaggaag catcttgctt ttatcagaat
     4021 cattgtaaac agccatataa ccgtcaaatt tcatctgact gccattggca acaaaaagga
     4081 cactattttg ctctaggtta accttaacag tatcaaacac agcagctgtc atctgactag
     4141 cgacaaagcg gttccaaatc aaggtataga gctttagctg atccttatct aaaaatttag
     4201 caatagcctc tggcgtatgg ttcacattag atggtcgaat agcctcatga gcgtcttgag
     4261 caccagtagc atttttaact cgattgccat gcttagagta ctgactaccg aaacgttcaa
     4321 caataaagcc tgcggcatca ttttgagcaa ctgggctgat acgagtagag tccgtacgca
     4381 tgtaagtaat taacccttgt gttccattag gaccaagact aatcccctca taaagctgct
     4441 gagcaaccat cattgtttta cgagtccgaa agttaatctt attggctgcg tcctgctgca
     4501 atgaggaggt tgtataaggt aaaggagcat gacgcctgcg ttcttttttc tcaaccttac
     4561 taaccataaa atcatcgcta cttaatcgag acaaaacaag cttaacatca tcattggtat
     4621 tgagcttcat ctttttgcca ttgaggccgt aaaagcttgc ttggaatttt tttgtccctt
     4681 ttttaaagag accatcaatt gaccaatatt cttcaggaac aaaggcctta atctcatgct
     4741 ctctgtcaat gattagcttt agagcaaccg attgcacgcg ccctgctgaa agcccctttt
     4801 taaccttttt ccagagaatt ggcgaaatgg aataaccaac aatacgatcc agtacacgac
     4861 gtgcctgctg tgagtcaacc aaatccatat caatttttct tgggccttca aaagcttctt
     4921 tgacggcatc ctttgtgatt tcattgaaaa cgacacgatt gttatcatca ggatcaagtc
     4981 ccaaaatatg tgataaatgc catgaaatgg cctctccctc acgatccggg tcacttgcta
     5041 gataaacctt tttagcattc tttgcttctt tttttaaggc attaatcagc ggacccttac
     5101 cacgaatatt aatatactgt ggctcataat gattgtcaaa atcaatagac attgatgatt
     5161 ttttcaaatc acgaatatga ccaaccgagg caacgacctt atactgacgt cccaaatatt
     5221 tttcgatggt tttagcctta gcaggtgatt caacaatgac tagatttttt ttagcagctg
     5281 ctgatttttt ctttgtagca gatcttttcg tctcttgttt tgacttagtt gctgtttttg
     5341 ttaccaattg acacacttcc tataacagtt atggttaaag cttctagcat aatatcccat
     5401 tttttaagaa ctgtcaacaa aaaattttct ataaatagga agaaaagtta agaatagtgg
     5461 tattctgaaa gaatgtctct gccatgagtg acacagctgg caccatcttt gatcagcttc
     5521 aaacagcccg ccgatgtccc attaagaata ttgtcaggta cgacaaaaat atcacgtccc
     5581 tcttccatag ctagctgaca ggtaatcaaa gagccagagc gctgcttagc ctcaacaaca
     5641 aggacacctc gactaagacc tgcgataata cggtttcttt cagggaaatg ataagacaag
     5701 gcggcctctc cagccccata ttcactgagc acgagatgac gctgagataa aaactcctgt
     5761 agctggtgat tttcctttgg atagtagcga tctaggccag tcccgataac agctatggtt
     5821 tgcccacctg ctttcaagca agcgagatga gcactggtat caatacctct agcaagcccg
     5881 ctgacaatga caaagtgatt cttaagctct ttgatgattt tgtaaacaga ccgcgtccca
     5941 atttcactgg attctctaga gccaacgact gccagcttag gcttttctaa caggcttaaa
     6001 tcaccttgat aaaagagtaa aacaggagga ttatagattt ccctcagggc caatgggtat
     6061 tgcttatcta ggatagataa gctcggaaac tggttgaatt ccttttttaa caaggcgaca
     6121 tttaattgct tgtaggtctc aataaataaa actggatttt tgcagcaaga aaccactgcc
     6181 atatctctaa gggatagaga cttgttatta cgctgctggt agtcaatcag gttaagaata
     6241 tttaaattag ttagcccagc cttttttaat ttataaagtt caaaattatt catcactgta
     6301 cctctctaat gatttattcg taaaaaaatt aaaaaagctc tgactaaaca aagctttttg
     6361 caaactcttg aggagctgta caggattcca gcaaaaaaat cgaggcctcc tagcctttgt
     6421 atgagcattg tagggcagct catcacatag cattccattg aaaaatacca gaattgtaga
     6481 tccacctagt ggctatcgtt tttgctttcg gcagctacct tttctcaaaa tgagattttt
     6541 agcgtaagat cattgatttt atcggctcaa agctttgccg atgaattggt gtgacaccat
     6601 actggtgcaa tccctgcagg tgctccttgg tcccatagcc ggcattttta gcaaagccat
     6661 agcctggaaa ggccttatcg taatcaagca tcaatcgatc tctggtaacc ttagccacaa
     6721 tagaggctgc agcgattgac atagagctcg catcgccttt tataatagcc tgttgaggaa
     6781 tagaaacctc tagtgtcatg gcatcaatga gcaggtaatc aggcttactc acagagccct
     6841 ccagctgatt aatggcagct gtcattgcta attttgttgc ttcatagata ttaacccggt
     6901 caatggtatg gttgtcaata attccaagac cgattcccaa cgctttcttt tgaatggctt
     6961 ggtaaattgc ttcatgctta gctttaggaa tttttttaga atcatttagc cccttaatgg
     7021 tgcagccctt tggcagtata acacaggctg ctacaactgg tccagccaga ggacctcgac
     7081 caacctcatc tataccagca atcgcttgaa agcctttttg gtaaagcgcc tgttcatacg
     7141 tcaacatcgc ctcaagccgg gcttcctctt ttaagatagc ctctaaagcc ctttttctgc
     7201 tagatacagc cttttgaacg ccaagccgct tatccgcctt tagctcttca aaaaatggat
     7261 cagaaagact agaaacagct tctagacgag ctttaatgtc tttaatagtc attgctgtca
     7321 tcatcaccaa cctgatctaa ggtgtactga ccaagtcttc catcacgaat atccttgatg
     7381 aataagctgt aaaaacgatc atagtcttcc ttaaagccaa gctgacgtgt caaggacatg
     7441 atgatttctg gagcgtcagc ctctagatca atagccttaa aacgctttaa taggcgatta
     7501 ggataatact tcttaaaata attcaatcca aaaatcgtga cctcgtccat tggcaacagc
     7561 tgatccttaa tagcccctgt cagggctaat tttaacccaa ccaattcgtc ttcaaacttt
     7621 ggccataaga tacccggagt atccaatatc tctagttctt tattggattt tagccattgc
     7681 tgtcccttgg tcactcctgg cttattgcct actgtggcaa ttttttttcc cgccaagcga
     7741 ttcatcaggg ttgatttgcc agcatttgga atgccaataa tcatggttcg tagcgtttct
     7801 ttttgaatgc ctcgttctct taagcgacgt agtttatctg ccatcaattc cttagcagcc
     7861 tcggtgaccc ttttgaccgt agcctgttcc ttagcattga tagctaatgt cttaatccct
     7921 tgcttctcat aatattgttg ccatttctta gtatgcgtgt tatctgctag atcagcctta
     7981 ttaagaagca ttagcttggg cttatctcca acaattttgg tcagcatagg attttgactt
     8041 gataaaggta gcctagcgtc tactaaaatc gtcacaaaat caacatgctt aatattttcc
     8101 tgtacctgtc tccttgcctt ggacatgtgt ccaggaaacc attgaatcgt agccatgtgt
     8161 gtaaaatcct ttcgtatcaa gggtttttag cccctcgtct tttaaaaatc atgcgagtca
     8221 ccaaaaaatc accaaatatt aagcattatc tccagaccaa gcgatataat tgcaacttgt
     8281 tttggttatt tttaatgcca acaatatcaa atgatttcta atggtatctg gcttatagct
     8341 attctctgct gaatagattg cctcttcaat tttaccctgt aatctcgctc agcctgtctc
     8401 ctgaccttgc ttttacatat gaaactgtaa tattttccat tttaccagtt atatgataaa
     8461 gaaaatcaaa atagtcgtag tagaataaat tactttaaac tattatagca cgatttccct
     8521 tattttactg ctaaattatc ctttgtaaaa gaagatatta atcgttataa agaccaaaaa
     8581 agagaagacc aaaatgatcc cctctagtct tcttttcggc atattttacc gttatttggc
     8641 caactttcca ctaatgtgag taaaattgta ttctaagcaa gctttaccta ttaacttagg
     8701 agaaaacata atctctatag ctaaaaatac caaaaaaatt atgaatcatt atcgcaaact
     8761 atccatagtg atcacttcat cagccatttc ccatattgct ggattatgag ttgctacgat
     8821 gattaatctg ttagcgtcac gaagagacag tacaatctcc ataatcaact tggacgtggt
     8881 tggatctatt gaagccgttg gttcatctgc caaaataaat ggcggatttt ttaagatgat
     8941 ctttgctaag gcaactcgtt gtgactaacc cccagatagc tcaaaaatgc gtttatctag
     9001 gttcagatag gataaaccta cacgttctaa ggcctgtttc tgtctcatcg tttgctcaga
     9061 tttattcaat ttttgaccaa tgagaccaag tttgaggttt tcttcaatcg tttgattttc
     9121 aatcaaacca aaattttgga ataggtaacc caattcatga cggaaaaaat cactagattt
     9181 atagctggct aagtctttgt ctcggtaaaa aatagtccca tgataaggtt ctaatttccc
     9241 catcatgttc atcaaggttg ttttcccgct accgcttgaa ccaatcaaag catagacttt
     9301 tccaacctca aatgtcattg aaagattaga aaatagctct cgttctccaa aagatttact
     9361 cacttgttta agttcaatca tgttaacctc ctttcaaaac aagcatggac atcttgtttt
     9421 ctttctgcat ttgaacatgt aattgtaaaa gagataggcc agtgaagagc aacaatacta
     9481 agaaagcaat cactatctct acttgaagga atacactcgc aacaaatccg agtaaaaaga
     9541 cacccaattg agccaggagg taattccgat ggatttctaa aaatcttagt ccagcaatac
     9601 gtttgatgac aatggcacgt ctaaattctt caaagtagag cctattcatg gtgttaaaca
     9661 acaagattga ggttgctatc ccaagcacag ctcccgcaag cattatccaa cgttccctct
     9721 ggatattatt caacaatgtg atgtagttct ggtatcctga ttgcatttct gagacccaat
     9781 tttcaatgtc ctgtctctgg ataagctcct gggcatcgga caactgatta aagaggacat
     9841 aattctgtac cgcgtcaaac caaaacatga cggactgagg tccagttgac tggggtgtta
     9901 cgacaatgat aatcggatct ttcagaaact gttgatagga aataggtgtc gtattataca
     9961 caaaacggtc ttggcctgat tccaaataag ccaccgtcgc aatcatttgc tgtcgaccat
    10021 cttgactaga catgcgacta gttaagtcgt cttcaaaaac agatttgtaa tgttcttcct
    10081 ctgaacggag atgctcaggc aagagcaaga caaattcccc tactgcgagg tgattcagtt
    10141 tttgttcaat agccgtatct acagggatgt tttgacgctc caagtattgc ggtgtgacaa
    10201 taaggacatt gccatttggg ctgtaatctt gccattctgt agaagttgtc aagtttttgg
    10261 aaaagtctta gcctttgtta tcaatacttg agtagcacct atgtttttca gattagcttg
    10321 ctcttgtaac tgttctgagc tattaaatgc tgtcatttca acggtgatat tttcagttga
    10381 ttctgcctgc ttgttatctt cttttgttgg agattctgga cgtttctcaa aataaaaata
    10441 attataaagc tgttgagccg ttactcctcc accagcccag ccagcaacag gttgaccatt
    10501 cttcagatat agtattgttg gtgttcctgg gattccaact gttttaaata aaaactcctg
    10561 agct
//
LOCUS       DARYVE010000067         9798 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYVE010000067 DARYVE010000000
VERSION     DARYVE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9798
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVW25_001681"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVW25_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1379292.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TVW25_001682"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TVW25_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            complement(5931..7601)
                     /locus_tag="TVW25_001683"
     CDS             complement(5931..7601)
                     /locus_tag="TVW25_001683"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1379293.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            7799..8491
                     /locus_tag="TVW25_001684"
     CDS             7799..8491
                     /locus_tag="TVW25_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1379294.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            8484..9029
                     /gene="coaC"
                     /locus_tag="TVW25_001685"
     CDS             8484..9029
                     /gene="coaC"
                     /locus_tag="TVW25_001685"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1379295.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            9086..9658
                     /locus_tag="TVW25_001686"
     CDS             9086..9658
                     /locus_tag="TVW25_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1379296.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         2864 a         2184 c         1842 g         2908 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt gctctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctttat taacaataga tttgtgaaaa attaatttta
     5701 tcatttaata ttaaaagtca gattattaaa aaatatccct accaaagcag aattaaagca
     5761 ttaatgattg tcaatatgac acctatactg gtaaaaaaag attgtgaata acgattaaaa
     5821 tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag attgaagaaa
     5881 ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa tcaaaacaat
     5941 cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat ctttggcaag
     6001 cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc ggtcttaggc
     6061 actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga tggatcgtct
     6121 gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc aaactgggca
     6181 aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc accataaatt
     6241 tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata tagacgctta
     6301 taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc aataccgcca
     6361 tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc tgcacacaat
     6421 tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat agctacaaca
     6481 atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc aaagccagac
     6541 cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc atgcatcttc
     6601 aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag attcggtgtt
     6661 ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc tgtaacagta
     6721 taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc atgagcaata
     6781 ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg aacaaggtta
     6841 ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa atcacgcaca
     6901 tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg agccttcaag
     6961 tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac tgtaatatca
     7021 aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat gacctgccta
     7081 agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg gtcaatacca
     7141 agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt atgagctgtg
     7201 gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg aagaacctga
     7261 gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa agagggctca
     7321 cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa accaatagac
     7381 atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa aatgagctta
     7441 ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc tttgtagtta
     7501 ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc tgtaatcggc
     7561 tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc ttgactctta
     7621 cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt tctatataca
     7681 aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt cagcattgtc
     7741 agtaaaaata attttaatta gtgattttat ttactattct tgctttttct gataaaatat
     7801 ggctatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg ccgttagagg
     7861 gattaccaat cattccactg gccagctagg aaagatagta gctgagacct ttctagcaaa
     7921 gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac agcagcctca
     7981 tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa aagaggaggt
     8041 tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc cagtgtacat
     8101 gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa cagcaagcaa
     8161 taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta aaaaaacacc
     8221 taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg gctttaagct
     8281 attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc tgcataaaaa
     8341 caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc agcacaaggc
     8401 ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc ttgcacaatt
     8461 aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc tcaggtagta
     8521 tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc tatgaggtta
     8581 ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta caggtcttat
     8641 cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt gtcaatcata
     8701 ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc aataccattg
     8761 ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta gccctgcctg
     8821 aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt aacccaatta
     8881 ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca cctaagacag
     8941 cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat gatatggtta
     9001 cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg ctgtattata
     9061 atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa tctctcgtat
     9121 tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt ttttttatat
     9181 ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg cttctatcat
     9241 gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca gtgtgatcac
     9301 aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca caaatggtaa
     9361 tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca ctccttatta
     9421 ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg ttggctcgct
     9481 gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag cctctggtga
     9541 caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg aaatgattgt
     9601 ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa aatcataata
     9661 ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg atatgtgaca
     9721 agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga aaataagtga
     9781 tttttccttt tcaacatg
//
LOCUS       DARYVE010000068         9459 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYVE010000068 DARYVE010000000
VERSION     DARYVE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9459
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            62..298
                     /locus_tag="TVW25_001687"
     CDS             62..298
                     /locus_tag="TVW25_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1379297.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TVW25_001688"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TVW25_001688"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1379298.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TVW25_001689"
     CDS             1637..1825
                     /locus_tag="TVW25_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1379299.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TVW25_001690"
     CDS             1857..2735
                     /locus_tag="TVW25_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1379300.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TVW25_001691"
     CDS             2749..2907
                     /locus_tag="TVW25_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379301.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TVW25_001692"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TVW25_001692"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1379302.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4880..7285
                     /locus_tag="TVW25_001693"
     CDS             4880..7285
                     /locus_tag="TVW25_001693"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1379303.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVENVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TVW25_001694"
     CDS             7520..8596
                     /locus_tag="TVW25_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379304.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TVW25_001695"
     CDS             8606..9310
                     /locus_tag="TVW25_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379305.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
BASE COUNT         2690 a         1976 c         2231 g         2562 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaaatgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaattat ctcaaaagtt ccttttactg atatttaata ttttctgtat ttttaattta
     9421 tagaaaaata aagaaacatg ctgagagttg atcaaaaca
//
LOCUS       DARYVE010000069         9331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYVE010000069 DARYVE010000000
VERSION     DARYVE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(7..369)
                     /locus_tag="TVW25_001696"
     CDS             complement(7..369)
                     /locus_tag="TVW25_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1379306.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TVW25_001697"
     CDS             complement(347..781)
                     /locus_tag="TVW25_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1379307.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TVW25_001698"
     CDS             complement(768..1058)
                     /locus_tag="TVW25_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1379308.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TVW25_001699"
     CDS             complement(1015..1440)
                     /locus_tag="TVW25_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1379309.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TVW25_001700"
     CDS             complement(1418..1741)
                     /locus_tag="TVW25_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1379310.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TVW25_001701"
     CDS             complement(1742..2728)
                     /locus_tag="TVW25_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1379311.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TVW25_001702"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TVW25_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1379312.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TVW25_001703"
     CDS             complement(3829..4476)
                     /locus_tag="TVW25_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379313.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TVW25_001704"
     CDS             complement(4478..6481)
                     /locus_tag="TVW25_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1379314.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TVW25_001705"
     CDS             complement(7018..7383)
                     /locus_tag="TVW25_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1379315.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TVW25_001706"
     CDS             complement(7444..8490)
                     /locus_tag="TVW25_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1379316.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(9054..>9331)
                     /locus_tag="TVW25_001707"
     CDS             complement(9054..>9331)
                     /locus_tag="TVW25_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379317.1"
                     /translation="RSFTGVNKIVFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPD
                     PIVSKVLAAALGVVSASISYANAAGRGVIVAFVGTFPRGVIHWVASQ"
BASE COUNT         2947 a         2118 c         1705 g         2561 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agcaataatg acataattca ataaaagaca taattaatca caacttgatt gtctttctaa
     8881 caaatccatt ccctgcctgg atcattagta tacgaaaaaa atgataggta aaactatacc
     8941 caataggcag aaaaaaactt tccaaaaaat agtattattt ttaaataatt tatcaacaaa
     9001 caccaataat atcaaattaa ttgctaaaca cagtattttt aaatataatg ctatcattgt
     9061 gaagccaccc aatgtatcac acctcttgga aaagttccta caaaggcaac aattactcct
     9121 cttcctgcag cattagcata agatattgat gcagacacaa ctcctaaagc ggctgcaagt
     9181 accttagata ctatagggtc tggaataaga cctgacaaag cagttgatcc ccagcctagt
     9241 gcagataatc tattcgcatt ggtactatct aaataaagat catagccttt ccaagtaaaa
     9301 acaattttat ttaccccagt aaatgatcta g
//
LOCUS       DARYVE010000070         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYVE010000070 DARYVE010000000
VERSION     DARYVE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            101..1027
                     /locus_tag="TVW25_001708"
     CDS             101..1027
                     /locus_tag="TVW25_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1379318.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TVW25_001709"
     CDS             1135..2421
                     /locus_tag="TVW25_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1379319.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TVW25_001710"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TVW25_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TVW25_001711"
     CDS             2977..3189
                     /locus_tag="TVW25_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1379320.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TVW25_001712"
     CDS             complement(4085..4225)
                     /locus_tag="TVW25_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379321.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVW25_001713"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVW25_001713"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1379322.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TVW25_001714"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TVW25_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TVW25_001715"
     CDS             8213..9118
                     /locus_tag="TVW25_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1379323.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYVE010000071         8516 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYVE010000071 DARYVE010000000
VERSION     DARYVE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8516
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..1203)
                     /locus_tag="TVW25_001716"
     CDS             complement(<1..1203)
                     /locus_tag="TVW25_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379324.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNG"
     gene            complement(1270..1575)
                     /locus_tag="TVW25_001717"
     CDS             complement(1270..1575)
                     /locus_tag="TVW25_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379325.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            complement(1742..2059)
                     /locus_tag="TVW25_001718"
     CDS             complement(1742..2059)
                     /locus_tag="TVW25_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379326.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(2041..3330)
                     /locus_tag="TVW25_001719"
     CDS             complement(2041..3330)
                     /locus_tag="TVW25_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379327.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(3332..3775)
                     /locus_tag="TVW25_001720"
     CDS             complement(3332..3775)
                     /locus_tag="TVW25_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379328.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(4140..7691)
                     /gene="smc"
                     /locus_tag="TVW25_001721"
     CDS             complement(4140..7691)
                     /gene="smc"
                     /locus_tag="TVW25_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1379329.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGVSKVVSVKLKDTQDLTYLS"
     gene            complement(7692..8384)
                     /locus_tag="TVW25_001722"
     CDS             complement(7692..8384)
                     /locus_tag="TVW25_001722"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1379330.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
BASE COUNT         2384 a         2000 c         1510 g         2622 t
ORIGIN      
        1 tccattaact ttattttgta ccttagcacc tgtttgatta atataaacca gttccttatt
       61 aacttctgga tgcgttattc catcactttt taattgctta gaaaaatctt ctgtaacatc
      121 agaagctgcc atatattctg gaacataggc tgaagatgat ttgatatata taaaatccag
      181 tttttttaag gctttagcaa tctctacgta cttagctcct gagtcatttg cttcttctcc
      241 attagtaaca gattcatttt caatacccaa aaactctggt cttttccaat cttttactgc
      301 actccatggt tttaaatgct ttatctgcat gtttatcttt gattgactag cctttgtttc
      361 ccgtaaaaag actcctgaaa caactattat gatagaaata accgcaagcc atacgataaa
      421 aatgaggcta tttttggcct tattttttat aatttcaata ggtttttcaa ccttaatagt
      481 tagccaaaat agaacaaagg tgatgatgtc aatgatttga aatatgatca aattagttaa
      541 aagcatagaa aaaaataact tggaactgta ggtgaaaaaa ccactaccca aaaaagaact
      601 ataagaaatc atcaataaag cggccataac cagttcaaaa gtaaatgaca tgaaataatc
      661 tcttcttagg tcgtgtacag gtaatcctaa agaacgtctt atcactcctt ctttaatctg
      721 tctcgctcta acaacaaata gaacaactaa taaggttaag taaattgaaa tcattagcaa
      781 taatctcaac ggaccagtaa attgtatcat tccccctatc tgccaagggt aagccagata
      841 tatgacttga agacctgtag atgtgagcgg ttttaaacta tttgaatcta atttccctag
      901 ggtataatac atccctgtga ttggtgcaga ctttaattgt tcatgattag tattatcaaa
      961 cttgatataa gtcaactgcc ccgaattttg aactaccggt ttgtaaatgg taactttttt
     1021 ctcttttgat aggtcactaa tcgtttgata cacttcttca ttagaaagat tgcttttccc
     1081 ttgaatggag aaggcaccat caattggtaa aggtattggt ttttgagtat cattaatact
     1141 aaccagacca atggcagcaa ttaaacaaaa gaagaatcca acaatgcata attttaattt
     1201 cataagcacc tacctatatc ataaaaggcc ctatagcatt attgggcctt tagctttcat
     1261 aaaccatttt taaaatgtaa agtaattcca atgtgtattt aatcgaacat cattccagct
     1321 ttttgttgcg cttgagtttg cccatccata tttttgagaa tctctatcct taactgttcc
     1381 ccatagatta gttactgaag attttgaacc aatattattt ggagacttaa catagtcatt
     1441 agaataacca tagttatcac ttacaccata attccattca tcaataattg gatatggagc
     1501 tggatgcgct gttgctgcac taacaactct agctgtagca gcagatccaa aacttaaagt
     1561 gcttacagca agcaaaacta atgttttgtc accaattttt catattagtt ctcattggat
     1621 agattgttaa aaatatttga acaatctaaa taatatatta ttatttatta gcataatatc
     1681 atattattat ttgaattaca agatgctaaa ttgcaagtaa aagttagtca tcctatagaa
     1741 attatccgag tgacttgttg ttcaaaattt tccccaattt taaaaagaga tgaaactctg
     1801 cgttggattg atcctttaag cgacccaatt cattgaaaaa atctgatgca gcattggcag
     1861 ataggtctaa acgcttcaaa aaaacactca tcttctggta ctcagagttg atcaaatcat
     1921 ttaagacatg tcttctttca gataagctgt cttcacgctt ctgataggct cttttctggc
     1981 gtagaaagtc ctgctcggca tcatccatct cccgaagctt acgataaata gccacttcct
     2041 ctacaattct gtctgccatg ctctaaactc tcctgctaac tgacgatccg tttcaagctt
     2101 gctatcaata accgtctgaa tatctctatt caagttttca aagtctgtgg ccaaggctga
     2161 cagcttgctg accttggatt gagtatagtc ctgaaagtct tggacaaagc ggtcatatgt
     2221 gataccataa gaagcaaata aggcctgcac ctcatagtag ggcagctcat gaaaagagtt
     2281 gaagtcaatc gccgaccaca cttccataag ctttgcgtct gcaaccgttt tatgatccag
     2341 agcttcatca gccccctctc gagcagcctt agccatggac gagcctagga tcattccctg
     2401 tgccgcatct aaaaagagct cctcagaact actgatcccc ttgccggtag actgccagtg
     2461 ttttttgagc tgattgtagc ttgacatgct cttttttgag gcaaggacag ttaaataggc
     2521 ccgactcaca aggtattgtg ttccaatgag cttaccgtct ctatctacaa tctgaccctt
     2581 ttgattaaaa cgataagctc ctaaatcgtg ataatacaag gggttggctg ataagagcat
     2641 agcatcgaca ttccgagaaa tagctaaatc atcagttcca aaataggcac caaaattgcc
     2701 aatgccatca aaattaatgc ggaaattatt gtacatattg ctattagcct taacccatgt
     2761 gatagcttca gctgacatgc cgcgaacagg gtctggacca ttaaaggttg ttgctgggat
     2821 cttatgttct gcggcaacta ttagtgctag ataagctccg agagagtgac ctgtggttgt
     2881 taaggcagaa tgagggtact ttcttttgac ctgttgataa aacttttgag cagatcgtaa
     2941 ttggttttcg gcaataacaa aattgccacc atcaatattg ccgctgacta aatcatcttg
     3001 attgccccga atgagcagct gccaatccgt atcaagatct ctggaatccg cagcatttgt
     3061 ccctgcatag gcaatcacaa cctgagaggt atcgatatca cctttaacaa taggggctac
     3121 agccattgcc tgcataccgt tgtcattggt tttatgggca tcgttgttat tgtcctgaac
     3181 taagaggact cggtattgtc gtttagtgat aggatctttt acagttttac cagcaacaat
     3241 aacaaggtct ccatttgatt tagctttgct aggttcgaca ttataaacct gtttagccaa
     3301 ctcattataa ctactatccg atatcgccat attaatcctc ctgattgtcc tttgaataaa
     3361 tgacagtaac acctacaaga gatgttttat taatcttgtc aatcctatcc ataattcttg
     3421 gtttggtatc agtttcaggc ttttccatct tttctgtatc atcatcagta acaattcctc
     3481 gtattttctc aagactagac aagccatcaa acgaaaagcc tatttcattt tctccattta
     3541 taatcactat cgttccccac gaacctgttt cccgagaatg tccccagcct gtaaacttaa
     3601 cttctttaac cccttcatag tcatgaacca gcagcttagc aatactggtt tccaagtccc
     3661 ttttttgttg ttcctctgtt cttttgccat tcaaacgaaa aaccattatg atcgctccta
     3721 ttactattat taagcctagc catagccttt gcttattggt cttaactgtc atcatgtcct
     3781 cctttcactc ttttgctatg cgtccgtcac tctaaggaag gcagcatgac taattagggt
     3841 gaaatcaacg ccaaatctta tttatattat tctcattttg taattaaatt ataatataca
     3901 gacatctact tgtcaatata ttatgtcctt agttactttt ttggtatatt ttaatcaaaa
     3961 caagccgtac taagttccag gagcatgtca aaaacagcag cttactgcta gccaatcctt
     4021 gtgctttgtc ctttggaaag ccaaaaaacc taccatgacg ataggttttt ttatagctta
     4081 ttcttggtta tcatctgcta catgtagaaa tacagctaaa actaagctct gtcctagagt
     4141 tatgacaagt aagtcagatc ctgcgtatcc ttgagcttaa cagatactac cttagaaaca
     4201 ccagattctt gcatggtaat cccataaata ctgtctgctg ctgccattgt ccccttgcgg
     4261 tgggtaacca cgataaactg actatccttg tcaaaacgat tgagataatc tccaaaacgc
     4321 ttgacattgg cctcatcaag ggccgcctca acctcatcta aaatcacaaa gggaatggtc
     4381 ttaatgcgga taatagcaaa taaaagggct agcgctgata aggctttttc tccgccagac
     4441 atcacattca aagattgaag ctttttacca ggcggttgca ctgaaatatc tactccagca
     4501 gaaagcagat cagtctctgt caacatcaag tccgctgagc ccccgccaaa catctgccta
     4561 aaggtctcct taaagctatc acgaatagcc tcaaaggtaa ccctaaagcg tgccttaacc
     4621 tcatggtcca tattgccaat cgtatctacc aagagattct tggccttgat aaggtcagcc
     4681 ctttgaccat ttaagaaggc caaacgctca ctaacctcat caaattgagc aatagcatca
     4741 ctattgattg ggcctagggc acgaatgctt tgctgaacct gctgcaattt ctgtcttgct
     4801 gctgccatgt cagtgtcatt gattgggctt gcctgctcct tggcctcctc taagcttagc
     4861 tgaagctcct ctgataggct tctagcgtgc tgccgcaaac gaccaataac ctgctctaag
     4921 tcagcctcca gtcttgcctg ctgacgaatg aacgcttcat ttttcttggc ttccttaagc
     4981 aattgagcct ctagctcctc cagtctggcg tcatagtcct caccttcaaa gcgcagctga
     5041 atgaagcgct cctgagtctt gatcttgtct tgattagcct ctgtcagctg attttctagg
     5101 tgaggcaatt ggtcaatggc ctcctgacta acctgatgtg ataaaacagt ctccaaatta
     5161 gctaattcct tctgaccctg agcaatcatc gtctccaagc gacgctggtt agctgcttca
     5221 aactttttct cgttgagcaa atctcgctct ttaagacgag cctgagataa ttcctggcta
     5281 agctggtcct tcttttgctt aatcgtatct ttattttcct taatttgctc aatttctgac
     5341 gttaaggctg atttttcatc agctaggagc tgcaatgcct cctccagcct cgctttttct
     5401 gataataagc gctcactaga ctgaccagtc tgacggttgc tgagaagctc tagcagctct
     5461 tttgagtcag ccagcttttc tgctagctgc tgataggcca attgtgtttt ttgctcgacc
     5521 agtcttgctt gctcaccagc cagcttagta tcagcctgcg cagccttttt agccttcaaa
     5581 tcagcctgta cagcagctac tgctttttca gattccttga tctgctcaga aagcaaggct
     5641 aattccttct caatctgctc tagctctggc ttgataaagg ttgtgctatt gtgacgatta
     5701 gtcccccctg aaaaggcacc accgggacgc agctcggtac catcaagcgt tacaatcctg
     5761 accttataat gcagctgctt agctgcctga ttagcatgat caatggtatc aaaaatagcc
     5821 gtcacaccta acaggctttg tacaatagcg accaaagagg gctcataggt caccaaagaa
     5881 tcagctgtgc ctaaatagcc ctgacaagcc ctgagctgct tgagagtcac ctcagaaagc
     5941 tgacgggcct taatcgttgt cagaggtaaa aaggtcgcac gcccctgacg attagccttt
     6001 aaaaaggcta tcgctcgctt ggctgctgcc tcatctgcca cgataatatg ctgactacta
     6061 gctcccaaag caatctcaag tgccgtttga tactgactat caaaggtcaa atgctcacta
     6121 actgctccta aaataccatc tagcttacca gcagcctgaa gcactgccct aacacctgcg
     6181 taaaattgac tatgattttt ttggatagaa accaaactag ccctacgagc ctccttggct
     6241 tttttctgat ccaacaaatc aaaaagcctt gtctgtccct gatgataatc ctgctccaag
     6301 gcctcaactg tctttgctag ctcttgataa tcagctagga gctgctcaag tcttgattga
     6361 ctagcttgat aagccaaaag agcagtctgg gtgtcctgac tgagctgatt gaccttctct
     6421 tgtaggactt ggtattcctg cgcctgactg gctttcgcct gactttcctt atccagctgc
     6481 gctacaatag cggttaattg gtttgacaca tcagcctctt gctggagcag accaacaaaa
     6541 tcctcacgaa gagcctcaag cagctgatct ggatcgctag aaaatcgctc aagctcctga
     6601 gaaagctcgc tgaccttggt attaaactca gctaaggctt gatggatttc atctagctga
     6661 cgactctttt gctgatgctc ctgttgaaag gcaagcaatt gctcctgagc ctgctgcctg
     6721 cgctgactgg cttctgtttt cttttcctgc ttttgactaa ggtccagctt gatgaggtca
     6781 atctgtcgct ccagatctga tatgaccttt gtcaattcta gcaaatcagc ctgcgtctgc
     6841 tcagctacag cagagagctt ttgccgcttg gtttttagac ggtgattttc cgcctctaga
     6901 ctctgacgct tcctatgata ggccgctaga tcctcacgaa gagctactaa ggccttttct
     6961 tgagcctcct gctccatgcg gtcttgctct atatccttga ccaaaatatc cagctgcagc
     7021 tgcttacgat cagcatctaa ggctaaaaat tgcctagcag ttttcgcctg tctttctaga
     7081 ggaccagctt gatgctcaag ctcatagata atatcgtcta agcggtcaag attatcttga
     7141 gtttggttta gcttagtttg cgtctccttc ttgcgggtct tgtatttcaa aactccagct
     7201 gcctcttcaa agatggcccg tctttcctct ggcttactat tgaaaatctc ctcaacacga
     7261 ccttgagaaa taatagagaa cgaatcgcgc cctagtcctg tatccataaa cagctcgtga
     7321 atatctctta gcctaacttt tttgccatca atcagataat cactgtcgcc attgcgatag
     7381 atatgcctct ccacacgaat ctctttctga gcattcttaa taaaggcatc tgaattatcc
     7441 aagacaacag ccacctctgc ataattcaag ggactccgat gctcagttcc agcaaagatc
     7501 acatctggca tcttgccacc gcgcaggctt ttggcactgg cctcaccaag tgcccaacga
     7561 aggctttctg tcacattact ttttccagag ccatttggcc ctacaacagc tgtgaccccc
     7621 ttatcaaaga taatcttggt cttatctgca aaagacttaa agccctgcat ttgtatttct
     7681 tttaaaaaca tttagacctc actaagttgg gccagggcat ttttagcagc gtcctgctct
     7741 gccagttttt tagatctacc tgtccccttg ctaagatgat cctcaccaac caatacagct
     7801 acctcaaatt gcttagcatg agctggtcca gtctcgctaa tcacctgata atcaatcaca
     7861 acatcaccct tagcctgtaa caactcctgc aagcaggttt tataatcctt gaccttctca
     7921 aaagttccct gctcaacctg tggaatcata acctgattta aaaagcgacg aacctcttca
     7981 atgcctttat ccaaaagaag agcacccaaa aaagcctcga acaaatcgcc taaaatcgta
     8041 tcacgatgac ggcctcctga tttttcctcg cccctgccaa gcttaatata agcatcaaac
     8101 gaacaatagc gtgaaaagcc tgctaagctt tcctctctga caatcgttga tctgagtttt
     8161 gacatatcac cctcagtctg cttaggatac ttggcaaaga ggtattctga aataattaac
     8221 tgtagaacgg cgtctcctaa aaattccaaa cgctcattat gtgaaatgtt taggaggcga
     8281 tgctcattag cataagaggt atgtgtaaag gcagtctcta gtaatctttt atcatcaaaa
     8341 cggatattaa aagagttttc cagcagggcc tcaagctttt tcatcatgac aaatctcctt
     8401 ttctaatgtc cttataaacc attctattat aacaaaaatc cacttgaaag gcttatcaca
     8461 agtggatttt tcagaaatat tgtaccaaat aggcacgagc tattgactgc tgctat
//
LOCUS       DARYVE010000072         8260 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYVE010000072 DARYVE010000000
VERSION     DARYVE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8260
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(85..2385)
                     /locus_tag="TVW25_001723"
     CDS             complement(85..2385)
                     /locus_tag="TVW25_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1379331.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            2490..3746
                     /locus_tag="TVW25_001724"
     CDS             2490..3746
                     /locus_tag="TVW25_001724"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1379332.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAHEDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(3781..4590)
                     /locus_tag="TVW25_001725"
     CDS             complement(3781..4590)
                     /locus_tag="TVW25_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1379333.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(4583..5302)
                     /locus_tag="TVW25_001726"
     CDS             complement(4583..5302)
                     /locus_tag="TVW25_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1379334.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKPRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(5305..5748)
                     /locus_tag="TVW25_001727"
     CDS             complement(5305..5748)
                     /locus_tag="TVW25_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1379335.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(5818..6669)
                     /locus_tag="TVW25_001728"
     CDS             complement(5818..6669)
                     /locus_tag="TVW25_001728"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1379336.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(6884..7408)
                     /locus_tag="TVW25_001729"
     CDS             complement(6884..7408)
                     /locus_tag="TVW25_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1379337.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(7902..8003)
                     /locus_tag="TVW25_001730"
                     /pseudo
     CDS             complement(7902..8003)
                     /locus_tag="TVW25_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         2460 a         2030 c         1565 g         2205 t
ORIGIN      
        1 gttctttcta gctggacaat atttcagcta gattagacga caaatagtta tagatattat
       61 acactatttg tctggaaaat acaactaatt tcttctacca ctaaaacctc cccaggcttt
      121 ttgatagtct gcgtctgttc caccaatggc aaacctatag gtagttgctc cgggtccctt
      181 ttgagcccaa aggctggttg ttagctctcc accgatggag atggtttggc cattgatcgt
      241 cactgtaccc ggctttagac cagtggcctt caagacagaa gccttgataa caccaggatc
      301 cagtgaaaac cgctgaccaa ggccaaaaag attgggatca gcctgactga tggcattaac
      361 caaataagcc atataatttg aattattatt gtatcccgtc agtggtgcaa gcgaggtatt
      421 gtcatcatgg cctgcccaac cacccaaagt aacccttgga gtagctaaga ccagccagac
      481 atcggtataa ttttcggttg ttcctgtttt acctatccag tcagcacctg caaggcttgg
      541 gttgatccct gctaatcggc ttttaaaagt ggttgttgcc ccagatgaaa tcggccctct
      601 caagagctcc tgtaaaatcg ttgctgtcgg agctgagaaa atacgaaccg gcttggcctc
      661 atgctgataa acaacggatc catcactagc tgtgatacta gccaccatat attgcttttg
      721 ataaagacca ttattagcaa tcatctgata agcattggtc tgctgggcta ccgaggtctc
      781 aatcccacca ccaagtggca gactttcaat ggaataatca gcaatccgat atcccatttt
      841 actcatatag ttttcaacat caacgccctt atcacgcagc agcttttgag tccaaaaggc
      901 tggaatattc catgaggtat taagcgcctc ctgcaggggc atcattgctg ttccttcact
      961 atcgacgtgc atgatttttt gaccgctgga ataggtcgtc ggatagttgg ataggacact
     1021 agcacttccc attaatccct gatcaatggc aggtccataa gcaataatcg gcttaatgct
     1081 agagcctgga gagcgaacag tattaaaggc atgattgttt tgattttgag catagtctct
     1141 cccaccaata aagcccaaaa cagcacctgt agcattgtcc gttaggacat tgcccatctg
     1201 cactgtccca gtgccatcat ctaacaagcc accaaactga gctgccgctt tttgcatcac
     1261 ctgatggatt ggcttattga ttgttgtttt gacagtgtag ccgccatgct gcagctcagt
     1321 taaggctcgc tcctcatagg cagccttagt ctcatcattt tttaaatctt tagcaggcac
     1381 cttatctcgc ttaatcagat agctatacat ggccttttgt gcctctgcca agacagaata
     1441 gtagaggtaa tcatgagtat tggcagtgac tgtttcaggt ttgataaaat cattgctaat
     1501 aggatatgcc ttataatcac gatattcttt ttctgtcagc acacctgttc gatacatatt
     1561 gtagaggaca ttttgctggc gcttaatccc ataggccata tcatcggctg attttaactg
     1621 ccctgtcggc aaatacggcg aataaacaat cgggctttgc ggaagccctg ccaaaaaggc
     1681 cgcctgcgga accgtcaaat ccttggcaga gactccaaaa atgccacgcg cagcctcctc
     1741 cacacctgca atgttttgtc ccttattatt acgaccaaaa ggcgacacgt ttaaataatg
     1801 tgataaaata tcgtcctttg acatgtaacg ctctaaggcc agtgcataga taatttcctt
     1861 tgattttcgc ctaaaggtcg gatcatcgcc caagacttgc tgcttaatca actgctgtgt
     1921 cagcgtagag ccaccacttg actccccaaa gcccaaaaca gaggccagag tcgcacgaaa
     1981 aatcgccttt ggcacaatgc cattatggcg ctgaaagttg tcgtcctcag ttgagacaat
     2041 agcctttttg atattgtctg aaatcgcatc attagcaacc ggtgtcctaa gcagatccgt
     2101 atcaatgcct gaaatcaagc tattatctga ataggtaatc tgtgacatca tggtcaatga
     2161 ttcaacctgc ttgacaagac tttccttact tggaattttt accgagtcaa tttgactggc
     2221 taaatagcca aaggccatac cagcacccag catgccaaat aaaaagacag ctacataaaa
     2281 aaagctcgac atgaatttta atgtgcgcaa aaagaccgtt ccaaaatcaa ctaattctaa
     2341 tcgctgatga tttttgcttg tttgattctt tttccatttc accataacgt acctcaatct
     2401 tcattatacc aaactttgat taagcttgca cagccacagt catttttgat ataatgattc
     2461 ggaaatcata aagaaaatgg agaaagccta tgaatatttt tgaagaactc aaagctcgtg
     2521 gcttggtctt tcagacgacc gatgaagaag cccttgtcaa agcattaaca gaagggcaag
     2581 tatcctatta cactggctat gatccaacag ctgatagcct gcatcttggt catctcgttg
     2641 ccattttgac atcacgtcgc ttgcagctag caggacacaa gccctacgct cttgtcggtg
     2701 gggcaactgg gctgattggt gatccgtcct ttaaagacgc tgagcgtatc ctacaaacca
     2761 aggaaaccgt tcttgattgg agccaaaaga ttaaagaaca actctcttgc tttcttgact
     2821 ttgacaacgg tgaaaacaag gctgagcttg tcaacaacta tgactggttc tcacagatta
     2881 gctttattga cttccttcgt gatgtcggca agcacttcac tatcaattac atgatgagca
     2941 aggattcagt gaaaaaacgt atcgaaaccg gaatttccta caccgaattt gcatatcagg
     3001 tcatgcaagg ctacgatttt tacgagctaa atgctaagca caatgtgaca ctgcaaatcg
     3061 gcggctctga ccagtggggt aatatgacag caggtaccga attgctccgc aaaaaagctg
     3121 acaagactgg acatgtgatg acagtgccat tgattacaga tgcaacaggt aaaaaattcg
     3181 gcaagtcaga gggtaatgcg atttggcttg acgctaaaaa aacatctcct tacgagatgt
     3241 accagttctg gttaaatgtt atggacgatg atgcggtacg cttcctgaag atcttcacct
     3301 tcttatcact tgatgagatt gctgctattg aggagcagtt caacgcagca cgccatgagc
     3361 gccttgctca aaagacactt gcgcgtgagg tggtgacact ggttcatgga gaggcagcct
     3421 accagcaagc cctcaatatt accgaacagc tttttgcagg agctatcaaa aacctttcag
     3481 cagctgagct taagcaaggc ttaagcaatg tccctaacta tcaggttcaa gcagaagaca
     3541 gcctaaatat cgtggatatg ttagtcacag caggcatttc accatcaaaa cgtcaggcgc
     3601 atgaggattt acaaaatggc gcgatctacc tcaatggaga acgacttcag gatctggatt
     3661 acagcttatc tacagcagat cgcattgaca atcagttgac cgtcattcgc cgcggcaaga
     3721 aaaaatacgc tgtactaacc tactaatcac agacagctag gaaaatcttg ctttggatga
     3781 ttatttttga cgtataaagg acagcaggtt aaccacaagg aagatcgcaa taaaaatcat
     3841 cgtaatggtc gcacttgccg gcgtttccca aaaataggac aagaaaatac cagacagcat
     3901 gcctgtaaag ccaatcataa tcccaagaaa aataactgat ttaaagtttt tcccaagccg
     3961 catagcaata cttgctggca aaaccataat cgttgatacc aaaagggccc ctgccgctgg
     4021 gatcgttaga gcaatagcaa cacctgtcac aatattaaac aagacagaca tgacacgcac
     4081 cggcaagcca tcgacgtagg ctgtgtcctc atcgaaggtc aagatataca ttggacgaat
     4141 aaataatatc gtcaaggcta aaataatcaa agcaatgaca aataaggcag caacctgctc
     4201 cgtactaata gtaatgatag agccaaaaag gtattgctcc aagctcatac tagaagagct
     4261 agttgactta ctcatgataa tcaaggaaat agccagcccc aaggacatta ggatagctgt
     4321 cgaaatctcc atatagtgct tataaaccac cctaagatat tctagcaaga tggcagctag
     4381 caccaccaca ataatcgttg tgaaggttgg cgaaacacca agaacaacac caaaggccac
     4441 accagccaga gaaacgtggc taagcgtatc actcaacaag ctttgacgac gcaaaatcaa
     4501 aaagataccc aaaatcggag caaagatact gatcgccaca acagccataa cagcacgctg
     4561 cataaaatca taagataaaa tctcaagcat ggaatgaccc tcctttgctc tcatcagcct
     4621 cagcatcatg aatgttgaag caacgccaag gaagccgttg atttctaatc aaatgaatat
     4681 tgcgatcagc ataagccttg acctcctctg ggtcatgtgt aatcatcaaa acagccttac
     4741 catgtctatg agcgctgtgg tgcatcaact cataaaaagt atctgttgtt ccactatcca
     4801 ttcctgtggt cggctcatca agcacaaaaa tatcggggtc agaagcaaac atacgcgcaa
     4861 taaccacacg ctgcttttga ccacctgata gactccctat tctcttatgc cgactatccc
     4921 acatgccaac agactccaag cttgtccgaa catgctcctc atcgtgctta cttagtctgg
     4981 taaaccaacc acttctagga tatctgcctg atttaacaaa ttcataaaca gtcgacggaa
     5041 agcctgcatt aaagctggca acctgctgtg gcaagtaagc aattctcagc tttttcccat
     5101 gaatgttctg tttagctata gtcacctgcc cagcccttgg ctttaaaatc cccaaggtcg
     5161 ccttgatcag ggttgacttg gcagcaccat tttcaccagt caatgtgaca aattctccac
     5221 tatccaaatg atagctgatt ccctctaaaa caggctcact gtcatactgg aacgagagat
     5281 tttccaccga tatgtatctc attattaccc ttctaactcc tccgcaaaag cagtgataaa
     5341 tttttcaaca atcacctgct cctccgcaga aaaatgtgcc aacaaacgat gataaacagc
     5401 tagtgtttta tcgtgatgat gtgtatgctc cttagcgatt ggccttgcta gatcagtcag
     5461 ttcaaaatag gttactcgag catcaacggt atcctttgtt cctgctagca tttcttgctt
     5521 gatcaagcct ttaatcgctt tagttactgc tgcttgactg atatttagcc tttttgccaa
     5581 atctgtattg gttagctttt cctgtgacaa aagcatcaaa atatgctcct gagtatttgt
     5641 taatttgaca tcactctgac aagccccaaa gagcagctca tgctgatttt cagcctttaa
     5701 caaaatacga ttaaccaaat tatcaagctt tttttctaaa attgtcatga tttccctctc
     5761 ctcattaacc agttaattat aacatgacgc cccaaaagac gcaacttcaa ggctgatcta
     5821 cagcgttcta accttgtaga cttccttaca aaagcctttc aggctattca ccacacgatt
     5881 ggcctgcttt tctgtttgac atagggcaaa taccgttgga ccacttcctg tcatcagggc
     5941 aatgtctgct cctgactgca gcattttatc cttaaccttt tgaataaacg gccgtttagc
     6001 aatggaaata tcctctaagg aatttcccat cgttgcaagc aagcgctgat aatcacctgc
     6061 ctcaatggct gaaaccagat cctcaatcgg cactcgagat atcgtctcac aatcaatatc
     6121 ccaaaaaatc gttctagtag aaatgccaaa ttctggcttc actagaacca cccaagagga
     6181 caagcggcca ttgattggct taaccacctc gcctttgcca gtcacttggg cgcagcctgc
     6241 aaaaagacaa taaggcacat cgctaccaat ctgcatgcca atgtcaatca tctgacgggg
     6301 actaagcttt agctgccaca gctgattcaa tgctctgatt gctgcagccg catcacttga
     6361 gccacctccc ataccagcac aaacaggtac cctcttatcc aagaaaatag agacacctgt
     6421 tgagatttga aatcgctctt tcagcaaata agccgccttg taaacgtcat tgtgctcatt
     6481 aataggcaat ctagggcaat tagaggtcaa taaaatccta tcctcctcta aatgatccac
     6541 tgtaatataa tcacaaagat ctacactaac tagaaccata gataggtcat gatagccatc
     6601 tggtcgcttg ccttgaatat ctaagcctag atttattttt gcaggagctc tctcaatgat
     6661 tgcagtcata atactccttt atttgatgtc attatagtat caaatataca caatcttcat
     6721 gaaaaattca aataaataca gttagtatct aatgatgcat agacagcgtg tttgtatcaa
     6781 aacagccaac catttgtccc tactagcgtg aggcttcacc agatcagcag ccaaaaaacg
     6841 acaactacta gcatagcaag caaagctaag acagcagcag tctctatgac cacttgatcg
     6901 ctccatattg ccccactaac tcaaagcaca tatcaatctt gctcttaaag tagggaataa
     6961 aaataccagc atcaatcatg gctaaaatct catcacgact agcccatcga acagcctgta
     7021 cctcctctgt ctgaagaact agcttcctta catcaacagc ctgcaaaatc aaaaaagtat
     7081 cgtcaaagcc attatcaaag gtaattgaaa aatgaggcct tacaccagct aaatcaagag
     7141 taagtcctag ctcctccttc agttctctca tcactgcctc ttgtgacgtc tcacctgcaa
     7201 gagcgctgcc gcctaccgtt atatcccaat agctgggcca accctcttta tccttttgcc
     7261 gctgctgaat cagcatttct cccttgtcat taaagacaca ggcgtgaacc actaaatgat
     7321 aagcaccctc tacaaaagca gctccacgct ccatgagtct accagtctta agacgattca
     7381 tcgtataaat gtcccaatac tcaaccatac aaacacacct cctgatacag ctattaccag
     7441 atccagtata ttaatcatat cacaataagc atatccaaaa caaccaggtc cagacaaaac
     7501 aacaattacc aacctagctt aattcttttt tctacaattc cctaccttaa aatgcctcgc
     7561 atagaaaatg gacaaaaaga tctgttttcc cgagacgtat caaaaagctc accacgctaa
     7621 caaactggta gttaagatcc ccaagcgtct tactcagtta acgatatggt gatacacaca
     7681 gctgacttgc ctcatcatat tagttacaaa aaaccttaaa ggctcaaccc aaaagcacac
     7741 caactacatc accccatgaa agaggaagac aaaacatcta ctgctgcaag caaaaagaga
     7801 ccccattagg gcctctctag tgctcatatc agcttttaaa ctaatcaatc gccttcaagc
     7861 taaaggctat catttagtag gagaaagttg caaaagctaa tttagttgtt ttttcttttt
     7921 agagttagca ggcctgcgct ggcaatgacg ccgagagctg caagggtgaa gaatgggtga
     7981 tttgtctctc ctgtagctgg taatataccc ttttgagctg ctggagccgc tgatttgctt
     8041 ggtgctgact taggcgctgg taccttagga ctagctgact gctgctctga agtctttggt
     8101 acctgtggag caggagattg ctccggggcc tttggagctg atggtttggt atcctttcct
     8161 tgctcgccct tttcaccgcg ttggctttgt tcaccttttt caccgcgttg gccttgttca
     8221 cctttttcgc cacgttggcc ttgctcgcct ttttcgccac
//
LOCUS       DARYVE010000073         8115 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYVE010000073 DARYVE010000000
VERSION     DARYVE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8115
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(2..2005)
                     /locus_tag="TVW25_001731"
     CDS             complement(2..2005)
                     /locus_tag="TVW25_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEL1379338.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKD
                     SGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKIT
                     YPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYL
                     IKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTM
                     IVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKR
                     PKRAQVYWFVNVRVTDEPYTATYKVDMLETDYIVCVELYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQAQDYTITPGREVGDFRFVIIEERVSHARQLSTLERFVMQTKASIKHVT
                     ASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA"
     gene            complement(2132..3748)
                     /locus_tag="TVW25_001732"
     CDS             complement(2132..3748)
                     /locus_tag="TVW25_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1379339.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(4164..5708)
                     /locus_tag="TVW25_001733"
     CDS             complement(4164..5708)
                     /locus_tag="TVW25_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1379340.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDFEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(5877..6572)
                     /locus_tag="TVW25_001734"
     CDS             complement(5877..6572)
                     /locus_tag="TVW25_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1379341.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(6656..8041)
                     /locus_tag="TVW25_001735"
     CDS             complement(6656..8041)
                     /locus_tag="TVW25_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1379342.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2468 a         1932 c         1519 g         2196 t
ORIGIN      
        1 cctaggcctt ttcatctttt gtacacgctt tgatttcctt gattggaagc tttaagacat
       61 ctgataagag taaaggaaca acctcaactg ttgcctcaga atattgcagg ccaaaccaac
      121 gcatagggct tgctgtcaca tgcttgatac tagcctttgt ctgcatgaca aaacgttcca
      181 gagtactcag ctgccttgca tgcgacacgc gctcctcaat gatcacaaac ctaaagtcac
      241 caacctctcg acctggtgta atcgtgtaat cctgagcttg cttaggcaga cgaccactct
      301 ccatcaaatc ctgaacaatc gttctaaggt aacgtggaac agtctgtggc attctaaagc
      361 caaggtagag ctctacacaa acgatatagt ctgtttctaa catatccacc ttgtaggtcg
      421 ccgtataagg ctcatctgtc acacgaacat taacaaacca ataaacctgt gcgcgcttag
      481 gacgcttatc taaaatagaa tacaggattg agcgatcaat cagatctttt ttcatgcgat
      541 tggtcaagta aacaacattg gtctgataca aatcaaagcg aagatcatct ctgaggagct
      601 tgatttgatg cttgtaatca tttaggctca aggacttaac atatttagca acaatcatgg
      661 ttccagcatg ccaaatcacc ataacaaaga caatggcaag agctaaaaca acaacaacat
      721 agcccccatg cataaactta actgcagacg ctaaaaagaa aataaactca ataaaggcaa
      781 aaaaagccat gagcagacta gccaggagcg gctttacccc ctccttaata aggtaatagg
      841 ctaagagaat cgttgtcatc agcatggtaa tcgtgatggc aaggccatag gcagcctcca
      901 tatgcgctga tgttctaaaa tacagcaccg tacaagacgt taccgcaaac aagctccagt
      961 taatgacagg gatgtatagt tggcctaggt tggcacctgg ataggtaatc ttaaacaacg
     1021 gaaaaatctt caagcgcata gcctcagaaa ccaaggtaaa ggaacctgag attaaagcct
     1081 gcgaagcaat aatggctgct agagttgcta gaataacaag ataaacccgt aatccctctg
     1141 gaacactagc aaagaaggga ttaagcgcaa tgcctgagtc cttatgcgct aaaatccaag
     1201 ctgcctgacc acaataggat aagatgatac aaaccttaac aaagggccag ctagcataaa
     1261 tatttcctcg accgacatga cctaaatcag aataaagagc ttcagcacca gttgtcgcta
     1321 aaaaaataga gcctaaaatg aaaatacccc gatgattttc cggactaacc aataagtgca
     1381 gcgcataata gggattgata gcctttagga tttccaaatg ctgtaagcta ttcaagagac
     1441 cactgatccc caaaacgcta aaccaaacca gcatgactgg cccaaataat ttaccaataa
     1501 cacccgttcc aaagcgctgc aggccaaaca agaccatcaa tatcagcaag gtcgttagga
     1561 tcacattggt ctgattctgg taaatactgc tgagctcagg aacagccttt aagccttcaa
     1621 tggctgatgt gaccgtaaca gctggtgtca aggcaccatc tgataagagc gttgctcccc
     1681 caagcatagc tggaatgatt aaccaccttg acatccttct aactaaggta aagagtgaaa
     1741 aaatccctcc ctcatgatga ttatcagcct ttaaagcaat caaaacatac ttgattgtcg
     1801 ttaccaaggt tagagtccaa ataatcaagg atactgagcc taaaataaaa gcttcagaca
     1861 cctgtgaaag gccgccttga ttgtcaacca acgactgcat ggtatacagt ggacttgtgc
     1921 caatatcacc atagacaatt cctagtgcaa taataaaacc tgcctttgtt gctttatcaa
     1981 aggcatcatg atgggcatta gacatcccaa tgttcctcct aagacttaat catgccaaat
     2041 ggactgagac cattatagca aaatctataa caaaatcaat attttcagaa aattaaaaag
     2101 agagctgaca atcatcagct ctcttgaaac tttagttccc tttatgacgg ataataaatc
     2161 cagacgtctt agcttcgaca gccttgccct tcttgtgcag gtccttgtta gagcgttttt
     2221 gctttcgctt aaagtcatag ctaccactgc tatcatgact gtcacgttta tcacgccttg
     2281 gacggcggtc accatcataa acatttcttt tctcatgacg atagccacct cgacggttat
     2341 cacgaccgct acgactacga ttgccacgac ctgtcttgcc atttttattg ccatgaccac
     2401 caccaacata cttaaacggt aatggctttt cacgcgctat ctcaacctct ggtaaggtat
     2461 ctggatcttg gacggtcaag ctaaggatat agagcgctag ctcctctggg gtaaactctg
     2521 ctgccaattt catcgcatcg cccttaaatt tctcaaagtt tgagcgaata gcatcatctg
     2581 caaaatcacg ctcaattttt ttgagggcaa cctttttctt agcctgaaag gcttcctctg
     2641 ccgtagctgg cttgagtggc ttcatgcgct tcttagtcag gtgctcaatc atggtcagat
     2701 agcccatctc atttggtgag acaaaggtaa tggattcccc tgacttacct gcacgaccgg
     2761 tccggccaat acggtgcaca tagctttctg gatcctgtgt aatatcgtaa ttgtacacat
     2821 gagtaacgcc tgaaatatca agcccacgcg cagcaacatc ggttgccact aaaatatcaa
     2881 gttgatcatt tttaaagtcg cgtatgacac gaaggcgctt attttggtca aggtcaccat
     2941 gtatcccttc tgcgcgaaaa ccacgcaatt ttaagccgcg cgtgatttca tcaacacgac
     3001 gctttgtgcg accaaataca attgatagct ctggctgctg aacgtccatc agacgtgtca
     3061 tggtatcaaa tttttcttgc tccttaacac gcacatagta ttgatcaaca ttcacatttg
     3121 ttaattcctt gtttttaacc tgaacatgct caggatcctt cataaacttg acaccaattt
     3181 ccttgattgg agctggcatt gttgctgaaa ataacagggt ttgacgatcg tcagggacac
     3241 gactaataat cgcttcaatg tcctctaaaa atcccatatt caagcattca tcagcttcat
     3301 ctaaaatgag tgtctcaaca tggtctagcc tcaaggcctt acgcttaatc aaatctaaca
     3361 gacgtcctgg cgttccaaca acgacatgcg ccccagactt tagggcctta atttgcttct
     3421 caatgcttga gccaccatat actgagcgaa ccttgacgcc tttatcacga ccaaaacgga
     3481 acagctcttc ctgactttgg acagccagct cacgcgtcgg agcaatcacc aatgcctgaa
     3541 tggtgttatc ggctgtacga atcttattca gagttggtag accaaaggct gctgtttttc
     3601 ctgttcctgt ctgagcctgt ccgataacat ctcgtccctc caaggctaac ggaatggtca
     3661 gctcctgaat aggagaggct ttttcaaagc ctgctgtaac aacagctgac tgaatatctt
     3721 ctgataagtt aaatgctgta aatttcaatt gtttctcttt tctaaaaagg cagtgcgaag
     3781 ctgccttata aaccttttaa tattgtcgtt cgattaacaa cctatttagt gtaacataat
     3841 taatattaaa aagataggaa ataagccatg aaagtgtttt tatctcaaaa tgattaacac
     3901 tatcaggcag ctaaattgat aaaagcgtca ctccttattg ctgattggct aacagcctca
     3961 aaaaggcctc gtcggacttg cttacctatg ctttttatct actctgctaa aaagactcgg
     4021 cacagagacg agccttcgcg attccatcac caatcttcaa agacagcaat taggattcct
     4081 gaaagctcct tatgccaata gcctgccttt tcttagcagc agaagtgcaa aaacggacta
     4141 ggttccccta atccgcttag ctgctacatt tttgcttcta gcttaacatc tgggtattta
     4201 tctgcaaacc aacgaagcgc aaagtcattt tcaaagagaa aaacaggctg atcaaagcga
     4261 tcccttgcca aaatgtttcg gcttgaggac atgcgttggt ccaaatcctc ctctgagatc
     4321 caacgaacag tctttttgcc cattggtgtc atgatgacct ctgcattgta ctcaccctcc
     4381 atacggtgct tgaaaacctc aaactgcagc tgaccaactg cgcccagcat gtattcacct
     4441 gtctgataat tcttataaag ctgaacagcc ccctcctgta caagctgctc aatacctttg
     4501 tggaaagatt tttgcttcat gacattctta ggtgcaacct tcataaaaat ctctggggta
     4561 aaggtcggca atggctcaaa ttcaaacagg tttttactaa cgctcaaggt atctccaacc
     4621 tgataagtcc ctgtatcgta gaccccaata atatcaccgg caactgcatt ttggacattt
     4681 tcacgagact cagccataaa ctgagtaaca tttgatagct taacgctttt acctgtacga
     4741 gacagcttta cagccattcc cttttgaaac tctccagaga caatacgcac aaaggcaatg
     4801 cggtcacgat gcttagggtc catgttagcc tgaatcttaa agacaaagcc tgaaaaatcc
     4861 tgattgaggg gatcaatcat ctggtccgtt gtcgtcttat gcccatgagg ctctggtgca
     4921 aaggctaaaa aggtatctaa aaaggtttgt accccaaaat ttgttaaggc agagccaaag
     4981 aataccggag tcagctgacc atctaaaata gcctgctctg aaaagtcatt acctgcctcc
     5041 tccaagagct caatatcttc aagcacctgc tcataaaaag ggttgctggc aaaaatcctt
     5101 gccccctcct ctaaatcagc aaacctctgc tcccccttat aaagctccaa gcgtttgttg
     5161 tgcaaatcat acagaccttc aaaggctcgt cccataccaa ttggccagtt catggggtaa
     5221 gaagcaatcc caagaacctc ttctagctcc tccaacaact ccaaaggctc acgtccatca
     5281 cgatctaatt tattaataaa cgtaaaaaca ggtatgttac gatgcttaac aacctcaaag
     5341 agctttttcg tctgtgcttc gatcccttta gccgaatcaa caaccatcac agcagcatca
     5401 actgccatta aggtacgata agtatcctct gaaaagtcct cgtgaccagg tgtatctaaa
     5461 atattgatac gcttaccagc ataatcaaac tgcatgactg atgatgtgac tgaaatccca
     5521 cgttgctttt caaaatccat ccaatctgac ttagcaaatt gaccagattt ttttccttta
     5581 acggtcccag cctcacgaat ctcaccacca aaataaagta actgttctgt aatagttgtt
     5641 ttaccagcat ctgggtgact gataatcgca aaggttcgac gctttttaat ttcttctgta
     5701 attgacattc ttttttcctt atttgttcac attgcagagc aagactctga ttaatagctt
     5761 caagtcacac gtcacagtta tgtctacatg atctcactcc taaatactga tatgataaaa
     5821 agagctgcta gagcagctcc tttattatag ctgattcgaa gcgctttttc aacgccctat
     5881 ctttctttag agagcttcag ctctaactga ttggcctcac taaatctcac atagataagt
     5941 tcaatcagct taattaaacc agtcaacccc attgtcacaa tgacaaaatt cataagcagg
     6001 tgatgcgtat gaataatcgg aatatccatc acaaagccgt aatttccctt tgttgccaaa
     6061 ttgatcaata ctaaaacaaa attaatggtt gccaagtaac ggcaaacaag gactggcttt
     6121 agctgacttg gattgtaaaa ccgcagcagg taaaccaagc cattgaccaa aagagcataa
     6181 tgccccaggt aaaaagaaat attagccaca tgccatagct gataagggta taaatcaggt
     6241 gataacaggg ccaaaaaggt cccaccaatc cctaaaacca taaaaagctg ctttaagcta
     6301 ctgcgatccg gtaagaaaaa gatagctagc atggccattc ggcaatggta aagcggcaaa
     6361 gcctctgtca acggaaagcc tcgcaaggca taccagctat acaaaccaac caattggacc
     6421 aactgaagcc ctaagaagat atagcgatac gactttagct gatagagctg cagggtcata
     6481 aaaaccaaaa acggcgctat catcaccgac aatagataaa atagcaagga cacatgcggt
     6541 agcccaatag gttcaattgc aaaaaaattc ataaacatcc ctttctacat tttttcatta
     6601 taccttaatc ttaatgagag gacaagatgt ttcatgtgtt ttttctgaaa aagtgttagg
     6661 aggacttccc agcatgagga gctgtcaggc gatcaaccac atttgctagc agcatggagt
     6721 ggctgccctt tagcagcatc tggtcattag gctcaagaat agtcaacagg tactggcaca
     6781 tgtcctcgta ttgatcctct cgattattct ttttaaagaa gctaactctg ccacttggat
     6841 aatcttgact agctagcttg gccaaggctt gaatatcatc accgtaaaag accaattgat
     6901 caatacgctt gggatctaag ctggtaatca gctgagaatg caaagcaact gagtcagcac
     6961 ctaattcctt catatcagct aaaacagcta tttttttgcc attagggttg gccggaatgg
     7021 cagcaaaggt ttccaaaatt aaccgcatag cagttggatt ggcattgtac acatctgcca
     7081 aaaggtcggc gccattagcc gccttgaccc actcggttcg gtggcgtgtc agcttgacgg
     7141 tttctaaagc ttctataata tcctcatcag gcacagccaa gagtttacca acataagctg
     7201 ctatcatagc attggttgca ttgtattttc cagttaaggg aagagtgacc ggtcttggta
     7261 agacattagt cctaaaggtc aaggagtcct tgcactcttt gatatcctca accaccagct
     7321 cttgatgatc gccaaagcga atgaccatct gactatccgg caaatatgga tcaaggatag
     7381 gatcaccagg agcaattaaa atcccgttag agtccatccc atcaacgatt tgcattttcc
     7441 cttcggcaat cttctcgcga gagccaaagt aggctaagtg agcctcacca ataagggtta
     7501 gcaatgcaat atgaggtctg gcaattctag agagcagctg aatgtctccc atatgatcct
     7561 gccccatctc taaaacaatc ttctcagtat cctctggcat gtgaagcacc gtataaggca
     7621 agccaatgtc attattataa ttgccctggg ttttgtaggt cttataagct tttgccagga
     7681 ccgcttcaat catatccttg gttgatgttt taccgtttga gcctgttaca gcaatgacat
     7741 cgacacgtag cttatcaata taatactggg ctaatttttg aaaggcagcc aagcaattct
     7801 caactagtat atagggtctg ccactgattg ctctttctga aaaggtagct acggccccat
     7861 tttcaaaggc taagtcaata aaatcatggc catctcgctc accctgtagc ggtaaaaaaa
     7921 gatcaccttt tgtgatgttt ctactgtcaa attcaatctg attcagagga acgtcgtcta
     7981 aatcagaaag actattttga gcatcaacaa ctcttgccac ttcatgtaat gttaatttca
     8041 tcttattttt cctcttaaaa cactggtttt taaagctttg cttatattat agcataacat
     8101 attaggaata ttctt
//
LOCUS       DARYVE010000074         7872 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYVE010000074 DARYVE010000000
VERSION     DARYVE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7872
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            60..2597
                     /locus_tag="TVW25_001736"
     CDS             60..2597
                     /locus_tag="TVW25_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1379343.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            complement(2795..3223)
                     /locus_tag="TVW25_001737"
     CDS             complement(2795..3223)
                     /locus_tag="TVW25_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1379344.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(3240..3584)
                     /locus_tag="TVW25_001738"
     CDS             complement(3240..3584)
                     /locus_tag="TVW25_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1379345.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            complement(3586..4056)
                     /locus_tag="TVW25_001739"
     CDS             complement(3586..4056)
                     /locus_tag="TVW25_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1379346.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4205..5941
                     /gene="pabB"
                     /locus_tag="TVW25_001740"
     CDS             4205..5941
                     /gene="pabB"
                     /locus_tag="TVW25_001740"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1379347.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            5982..6590
                     /locus_tag="TVW25_001741"
     CDS             5982..6590
                     /locus_tag="TVW25_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1379348.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            6583..7854
                     /locus_tag="TVW25_001742"
     CDS             6583..7854
                     /locus_tag="TVW25_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1379349.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
BASE COUNT         2342 a         1865 c         1637 g         2028 t
ORIGIN      
        1 ttaaccagta ataatattaa ctggttaagt taattgttgg aaggagttga taactaacca
       61 tgaaacaaca tcaacgattt ttatccctcg ttggactgct gttagcctgc aaccttgcct
      121 taacagcctg ccaaacgcat tcgcaaaagg gacattctca ggagcctaaa aagcaccaaa
      181 aggctacgaa aaagaaaaaa caaaaaagca gtaagactgc gaaaaaaaga gaacgtcacc
      241 aagtccctgg gattgatgtc ccaactgatg atggcttttt attgaccagc gaatcgcaaa
      301 ttgaacgcaa aacagataca ggtatcattg tgaagcatgg cgatcacaag catttcttct
      361 tttactcaga tttgaagggg acaaaatggg cttacctgat tcctaaggat tacaaggaag
      421 cacagcctgc ttctaaccaa gcggcaaggt ctggatcagt agtctcaact ggtcatgctg
      481 gagacggcta tgtctttaat ccagctgaca ttgttgctga ggacgcctat ggctacactg
      541 ttcgtcatgg agatcattac cactatatcc tcaaatcaag cctgccatca gcaaccatca
      601 accacatcgc atcaaccaca cctcacttcc catcaacacc acctagcatt catcagcagg
      661 ggggtatccc aggaattgac ttcaaaacta gtgatggctt cttatttgat ggcaccaaca
      721 ttagcggtgt cactgacact ggaatcctgg tgaagcatgg gaaccatttg caccctatta
      781 gctttgagga cttaaagcgt agcaaatggg cttatttagt ggagcaatat aagaaaaagg
      841 accacaccaa gcctcaggaa ggagactatc gcgcctatat agcttatctc gccaaggagc
      901 taaaggtaga tcaagcacgc attaagcagg tgaatgtaga cggtcaggtc ggctttgaat
      961 accctcatga ggaccacacg cacgtcatct ggctaaagga tattgatctt tctaagccat
     1021 ttaaaactcc agaagaacag atcctcaaaa agatagacgg agaaaccttt gaacagcgca
     1081 aagaaagact catcaaagaa tttatggatc gcttcaaggt tcgtcgtgag gacatctcaa
     1141 ttgagggcaa ctacatgacc attagtcatg gggaccatgc tcacatctat aagattgacc
     1201 cagaattgcc agatgatcct gagcgcaatg tcaagacaga atcaaccaat ctagaggtcg
     1261 aaactcagct cgtttatggt cctttctata cggaaaattc atctgaaaat ctaacacgtg
     1321 atggggtcta taaaaaatat cacccagagg gcatcaaaaa catcaaaaac tttatccatg
     1381 tgttgtttag tacaaatagt gaatacggcg acattgaggt taatggcatt aaaactaaac
     1441 gtgtgcacta tttggttcgt aaggatttgg actggaagga tttgaacatt cagcgtccag
     1501 aggcaatcaa gcatgagggg cgtatcttta agggctggag tgctgagttg ccaacagctg
     1561 gcaagatgga cagagaacat caacgcttct atgtagattt tgataaggtt agaaagcagc
     1621 ctaccaaggc tgtctacggg ccaggtgatg atgtttcaga ccttgactta gaaaattatg
     1681 ttcctgtctg gttcaccaca atctttaatg ggcgattgaa gcttaacggc gtgactcaag
     1741 gaggcttctt ctacaatgtt cgtagtggtc ttacctggaa ggaagctaag gagcaaggac
     1801 ttgttatccc tgagcccgtc ccagatccag gctatgaatt tattgaatac cgcagtggag
     1861 tgaaccttgc caataacttt aatctaactg attttgctaa gagattttct atcacacaaa
     1921 atgaaaacga taaggtagcc tttactggcc tattctcagc agcctttgga actactgctc
     1981 cttatattgg accttacatc gctgttaatc ctgacaagcc aactgatcta gaggatccta
     2041 gcagacaccc taattattac ttccacgatc cgagacacta tgtagccgtt gcctttaagg
     2101 caggagaggg cggacagctg attagccgag ctggtaaggg taagactgcc gtttaccttg
     2161 ttcgtaaggg acactcatta catacagctg gtatcctacc accatcagta cagccagatg
     2221 ccggctacaa gcgtgattac aataagccta ttatttcaac tgaggaatat gataaggaag
     2281 tcactgagga tattgtttat aacgtcaact ttgataaaat aaccaacaac gatgttacag
     2341 gtaatagtaa tcactcaggg aatacctggc taccaggtga tccactacct aaggagcctc
     2401 aaactcctaa tcacactggc agcactggaa gctggctaga agaatttgta gcgcccgttt
     2461 ctgactccga cgaggacgac ctattagcac ctgaccctga gcttgttggt aagacgccag
     2521 taagtgataa gccagccagc tattttttag gtgagtcaga gacagctagc agcacatcag
     2581 tagctagcaa cagctaagcc atagcaggac tgattgataa tatcaactac tcagctgatc
     2641 tggcctacca gattaaagac ttagccaccc caaaaacaaa gacgattgat cctagccaca
     2701 tgtgggcaga ggtcaatcgt ctttttgatt ctggtcgtag ctatcacata gtagtggtgt
     2761 ttgctgatct gtttagtgta ccagctaagt ctgcctattt ccttaaataa tcagctaagc
     2821 gagcctttag ctgaggaatg acccgatcgt ctgctaaaaa gtcatcaata gccatcagct
     2881 gataaccctg cccctcatca ccaaaagcaa tatgatctat catgtcctga ttcataagag
     2941 ccaccagaaa gacagattgg ctgtcaggat taacaagccc tggataaacc ctttcccaaa
     3001 cgacagcgtc cttagtcagt gccagaccta actcctcata gcactcacgt gacgcacaat
     3061 caaagggagc ttcagcattt tcacgaccac ctcctggtaa atcccacata ttagggtaag
     3121 gaatcgttgg tatcgcgtca cgcaagatgg tcaaaatctt accgttactg atcaaggcta
     3181 actttgcacc agaaaaatgg actgttttat ctaaaagctt catgactaga tctcaccaat
     3241 caacatagcc ttagctcaat accaacaacg ccatattggg cttgctgctc tttgctgtag
     3301 tactgttcca tatcctccgg ccgagccagt gccaattctt cattacgata accacatttt
     3361 tctaaaggca atgcttggta aagcttagca aagtcatcaa aataatgcaa ccctacgacc
     3421 tctgcttgca gaatatggct atgatcctct gtacaataaa agcaaatcca atcccctacc
     3481 ttaatagcct gccttttctc atcatttaac cgtagttcaa tagtcttcac acccgcctca
     3541 atcatagcaa atggtcttgg tgtcagcatc atctcatgta gcatcttaat acctcggata
     3601 gctataaagc tctgtttcct ctagtcctac ctgcccttcc tcaaaggcct cctcgttcca
     3661 ctctagacta aaatcaagct tgctatcatc tgctaagaaa tccatcaaat cgctatgccc
     3721 ttcaatggca acatcattga gaaactgggc aaaataggct aaaaattcac gagaaaagcc
     3781 cttttttggc tcaaatggaa tagccaccag atagtctgct gcttgaaact gtgatttctc
     3841 cggattgtaa aataagacat aatcctcaaa gacaatgtct tccttgctga gctgtccttg
     3901 gtcatcaatg gtttcaactg ctgactgatt ttgagcctct aaaacaaggg tgatttcaac
     3961 cgcatgattt ttcttgtccc aatccatagc atagtcataa tgaaaatgct tgtccatctc
     4021 ttcttctaat actgataaaa agccatattt agccatgctc ttgttccttt ttctaaataa
     4081 tatccgctac tattgtagca taaatcaaga agccctgctc tcttgtattg ttgatggttg
     4141 ctaacaggct tcttttcaac cctcctaatc agtctgaaaa gcgcatttat gatataatca
     4201 agctatgcat ataaagacga ttattgattt taaggagctg ggacaacgct atatatttca
     4261 agctcctatc gtggaattag tagctaagca gattgatcag gtgggacagg tccttgagca
     4321 ggtcaaccaa tttcaagatc tgggctacta tgttgtgggc tacctcagct atgaagcagc
     4381 agcctgtttt gacaaaaagc taacaacaca caataaaaga cttggtcagg aatattttgc
     4441 ttattttaca gtgcatgaca gctgtcagct cgaggacttt ccgctctacc acgacagcat
     4501 gacgattcca aacagctgga caagtgctac acaagaggaa gcctatcaag aggctattgc
     4561 acagattcat caggagatga ggcagggcaa tacctatcag gtcaactata ccattcagct
     4621 cagccaaagg ctaaacgcta aggacagctt ggccatttat catcaattgg tcattgaaca
     4681 ggcagctgga tacaatgcct acattgctca cgatgacttt gctgtcattt cagccagtcc
     4741 tgagttattt ttcaagcaag agaaaaacca gatcaccaca cgccccatga aaggcacaac
     4801 caagcgtggt tacaatttag aactagatca acaagagcat gactggctac aggccgatcc
     4861 taagaaccgt tcagaaaaca tgatgatcgt tgatttatta cgcaatgata tgaataagat
     4921 ctgtcaaact gggagtgtca cagtcacaca gctctgccaa ttggagcaat attccaccgt
     4981 ttggcagatg acctctacca ttgtcggcat gctgcaggat cagtgtcgtc tttatgatat
     5041 tttacaggca ctctttccct gtggctccat cacaggagct cctaaggtgt ctacaatggc
     5101 tattattaac cgattagagc ctaagccaag gggcgtttac tgtggcagca ttggtatttg
     5161 cctgcctgat ggcagacgtg tcttcaatgt cgctattcga acgattcagc tcagctacga
     5221 tcaggccatc tacggggtag gcggtgggat tacctgggaa agctgctggc aggacgaatt
     5281 tgaagaaatc aagcaaaaat cttcctttct gaaccgtcaa agcattgatt tcaccatcaa
     5341 aaccactgcc aaggtcgaac aacaaagcct aatatatcta gaccagcacc tcaacagact
     5401 aagggaggcg gcgcgttatt ttgcctaccc ctatgacgaa gagcttctga cagatcgttt
     5461 gcaagcctat ctcaagggaa aggacagcag cccctatcgt ctcactattg ctattgctaa
     5521 ggacgggcag attagcctta cagaccaaag cttagagccg cttcaaaaag actttttaaa
     5581 ggcacgatta gttcgccaat caagcgatgt caaaaagctt ccctttactt attttaaaac
     5641 cagtcatcga ccacatctga gcgtcaagcc ttatgagcaa gtctttgttg ctgctgatgg
     5701 gaccttgctt gaaacctcta ttggtaatct ttttgtgcaa atcgagcaga ccctttatac
     5761 accgcctgta tcagccggta ttctaccagg cattttccgt caagaattac taaggcaggg
     5821 actggctcag gaaaaagagc taaagctttc agatttagac aaggccgaag ccatttttgg
     5881 tggcaatgct gtccgaggac tctactcact aacaattgag gacaccactc tgcctcaata
     5941 gtaccaggct gatccctcag cactactaga tgaaggacct tatgatactt ttaattgata
     6001 actacgattc atttacctat aatctggccc aatacctcag tgcctttgat caaacgattg
     6061 tattgaccaa tcaggatcca aaactatttg accttgcgaa gcaggctgac gccatagtcc
     6121 tctcacctgg acccggctgg cccaaagccg ccaatcagat gcctagcttg attagggcct
     6181 tttatgacca aaagcctatg cttggcgttt gccttggcca ccaagctatc gctgaggctc
     6241 taggtggcag gctacgcctt gctaagcgcg tcatgcatgg caagcaaagt atacttgaaa
     6301 gacaagcacc agctaagctc tttcaacagc tgccaaagca attaaccgtc atgcgttacc
     6361 attctattgt tgttgatgac ctgccagctg actttgtaat taccgcaaga gactttgagg
     6421 acaatgagat tatggccttt gaacacagac agctgccact gtttggcctt caatttcacc
     6481 cagaaagcat cggaacagct gacggtagga caatgatcgc aaactttatg gctgttgtta
     6541 aaaagcacca cagccaacaa aagcaaggaa gggaggaata caatgcctga taatctagcc
     6601 atcagaatgc gccctagaac cattacagag gtcatcggcc agcagcatct ggtcggggag
     6661 ggaaaaatca ttgaccgcat ggtcaaggcc aatagattag cctcaatgat tctttacgga
     6721 cctcccggta ttggaaagac atcaattgct agtgctattg ctggaacaac caagtacgcc
     6781 tttagaacct tcaatgctac catagacaat aaaaaacgcc tccaagaaat cgctgaggaa
     6841 gctaagtttt caggtggact tgtgcttttg cttgatgaaa ttcaccgatt ggataagagt
     6901 aagcaggact ttttactacc acttttagag catgggcaca ttattatgat tggtgctacc
     6961 acagggaatc cttttttctc ggttactcca gccatcagaa gtcgagtcca gatttttgag
     7021 ctggagcccc tatcacctga ggagatcaag caggcgctta agcttgccat cactgataag
     7081 gagagaggct ttgcctttga tgtgacccta gatgaggctg cttttgactt tattgcgaca
     7141 gcgacaaatg gagatctccg agccgcctac caatcccttg atctagctgt catgtcaacc
     7201 cagccagata ccgagggtat ccgtcatatc agcttgaata ctgttgaaaa ttctttgcag
     7261 cgcagctaca tcacaatgga caaagatggc gacggacatt atgacatact atctgccttg
     7321 caaaaatcaa tccgaggatc tgatgttaat gctagcttgc actatgctgc aaggcttatt
     7381 gaggcaggcg atcttccgag tcttgctaga cgcttgacca ttatcgccta tgaggacata
     7441 ggtcttgcca atccagaagc tcaaatccat accgtcactg cacttgaggc cgcccagaaa
     7501 attggcttcc cagaggcgcg tatcctcatt gccaatgttg tgattgatct agcactgtca
     7561 ccaaagtcca attccgccta tatggctatg gacgctgctc tcgctgattt acgtcaacat
     7621 ggccatcttc ccattcctag acacctgcgt gatgggcatt atgccggcag caaggagcta
     7681 ggcaatgctc agcactacct ttaccctcat gcatatccag aaaaatgggt caagcagcaa
     7741 tatctccctg atcacttggt taagaaaaat tacttcaacc caaatgaaac aggaaaatat
     7801 gaaagagcct tagccgccaa taaagcgcga attgataagc tttctagcag ctagcctaaa
     7861 gaaaaaaaca ag
//
LOCUS       DARYVE010000075         7716 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYVE010000075 DARYVE010000000
VERSION     DARYVE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7716
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..405
                     /locus_tag="TVW25_001743"
     CDS             <1..405
                     /locus_tag="TVW25_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1379350.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TVW25_001744"
     CDS             414..1085
                     /locus_tag="TVW25_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379351.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TVW25_001745"
     CDS             1102..3375
                     /locus_tag="TVW25_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379352.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3849..5870
                     /locus_tag="TVW25_001746"
     CDS             3849..5870
                     /locus_tag="TVW25_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1379353.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKE
                     EAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAK
                     NKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEA
                     NKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKA
                     RITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEK
                     TALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQGMQSHQG
                     QEKPKDPKTPETPKDPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSPQ
                     TGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLNLSPRRKKNQNNR"
     gene            6287..7129
                     /locus_tag="TVW25_001747"
     CDS             6287..7129
                     /locus_tag="TVW25_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1379354.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(7232..>7716)
                     /locus_tag="TVW25_001748"
     CDS             complement(7232..>7716)
                     /locus_tag="TVW25_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1379355.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         2552 a         1595 c         1541 g         2028 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa cgaaactacg gagagaaaga tgagctttgt cgtttctcac ttccaaccgc
     3781 catgttaaaa tcttctctga gaaagaatgt tataaaaaat aatcattcta tcaccaaagg
     3841 agagaaaaat gataactaaa aaacagagaa aactaaaaag acacacaaca atcagacgcc
     3901 tgtgtcatca agccctagca gctaccctca tcacaggaag cctgatggga acaggactac
     3961 ttggaaataa agtcgtgtat ggggatatga aaagcgatgc caaaaaggta ttagcaacat
     4021 tgcaaaaagg taatcataaa caagagttaa aaaaagttct tagaactatt ggtgatgata
     4081 gtttgctatt attatggtta cttgtatcgg gtgattccaa tttagatgaa agtaataaaa
     4141 gttttgatta tttatcaatt tggaatactg gatctagagt tggtaaagtg atatctccta
     4201 ctgaatactt taaacaagaa tcaaaaaaca ctgaaaatag gcaagctgtt tatagtgaat
     4261 ttaaacaacg cgtagaagaa cgatctaaaa aagccaagga agccactgaa gcactaaacc
     4321 aaaaagctca attggaggct acagttaaaa atataaacga agaacttgaa aaaactagag
     4381 aaggttttaa agttgtgagt gaaaactcaa acaaattaga aaaacaatta atggctgaga
     4441 aaataaaaac acgtacagct gaagaaactg ccaaacaagc taaaaccgat aaagaaaaag
     4501 cagaggctga agctaaaaaa gcgaaagagg aagctaagac tgcggaagga aaagttaaac
     4561 aagcagaaac tgagaaaagg aatgcggaag ctaaggctag aaccgctgaa gaagaagcta
     4621 aacaagctac ggctgataaa gaaaaggcag agactgaagc taaaaaagcg aaagaagaag
     4681 ctaagaccgc taaagaagct gctcatcaag aacaagaaaa agctaaacaa ttagaacaag
     4741 ctaatcaaca ggctaaccaa agagctaatc tggcagaaaa atctaaaaaa gatttagaaa
     4801 ctcaaaaaga aaaacttgaa caagagatta aagaagctac agaagctaaa aacaaagccg
     4861 agcaaaaatt aaaagaccta caagattcag ctagtcaagg cagtgaattg tctaaacagc
     4921 tgttaaaaga aaaagaagaa ttaacaacaa aacttcaaga gcttcaaaaa caagctgagg
     4981 aaaaaacaac tgaaattgaa aagctaaaac aagagcttga agctaataaa caaaacagtg
     5041 gtcagctagg tcaacaggaa caaaagcttc aagagcaatt gaataaggtt caaaaagagc
     5101 tgaaacaaaa ggaaatggag ttaaaacaag ctcaagaaca gctgaaacaa gaacaaaaac
     5161 ctcacgaagg tggcggagat tctgacgctt ccaaagcaag aatcactgag ctagaaaaac
     5221 aagttcaaac actaaccaag gaaaaggcag atctgtcatc aacccttgag tcaacaaaag
     5281 ctcaattgtc agagactcaa gcaagactat cagaagctca aaaacaattg actgctgctc
     5341 aagaaaagtt aacaacactt gaagccgaga aaacagcgct tcaacatcaa gttgagacca
     5401 tttcaaaaca gctatcagaa acacgtgacc ttagcgaaaa ggaaaaagca gcactccaag
     5461 agcaaatcaa taagctaaag gctgagattg agcaaaagac caaggaaatt gaagccttaa
     5521 agcaaggcat gcaatcacat caaggtcaag aaaaaccaaa ggatccaaaa actccggaaa
     5581 caccaaagga tccaaagact cctgagaaaa acgatcagcc acaagcgcct gaaaaacgta
     5641 gtgtcccttg gactgctctt acaccagcta agccaattga cactaccaaa gctcctaaga
     5701 gctcagcacc aagcccacag actggggcag caacacctaa aaaacaatta ccagcaactg
     5761 gtgatacagc gacacctagc ttctttaccg ctgctgctat ggcagtattg gctagcgtcg
     5821 gtgtcctaaa tctctcacct agacgcaaaa agaatcaaaa caaccgttaa tgtagagact
     5881 ctcatatctg gattgaataa cagcaaaccc gacatgagca aaaacaaatg tctaaccaaa
     5941 aatcactgac attagtactt taaccaaagc ctttgagtca agctaaacag gctgtcctgc
     6001 ctattggctt gactcgtttt gtgattgtga aacacaccaa ggtcaaacct accttgtcct
     6061 ccattttaaa cctactcttt tctcccatac ccactttagc ttacgcaaga aggtgcctaa
     6121 tcatcacttt tggtagcttc gatgctctat ataaatggat caacaaagat aaatcataca
     6181 aaactgcgag ttgttcctat agtcacgata gctcttacag atatgaaaag taaatacagc
     6241 tattaaaaat atggtacaat aggggtacga tttttaggag gcatgtatgg tttcagttct
     6301 ttcacgagtg attaagggaa taattattgc gcttggcttt attttaccgg gagtatctgg
     6361 aggagtatta gccgctatcc ttgggatcta tgagcgtatc attgcctttt tagctcatat
     6421 acgtgagcat tttgttgaga atgttctctt tttcctgcct gttggggttg gtggtatttt
     6481 agggattgcc ctcttttctt accctgttga ctatctgctc aagcactatc aggtaccagt
     6541 cttatggggc ttcgctgggg ccatcatagg aaccgtacct agcctgataa agacttcgac
     6601 aaaaacatct cagcgtgacc aagttgattg gctctggcta gtattaacct ttgtcctatc
     6661 aggactggga ctttatttct taaatgatct cgttgggaca atacctgcaa gctttaccgc
     6721 ctttgtccta gctggtgcct tgattgcttt aggtattttg gtacctggtc ttagcccgtc
     6781 taatctttta ttaattttag gactttactc acccatgctg attggcttta aatcacttga
     6841 tttggtagga acctttttac ccattgctat tggtggctta ttaaccatgc tagctttttc
     6901 caagattatg gattttgctc tcaagcacta ccattcacgc gtttaccact ttattatcgg
     6961 tatcgtccta tccagcaccc tgcttatttt aattccaaat agcagtaata aggaagctat
     7021 ctcttacgcc ggtgcaggtc ttggcacctg gctaatggct ctgctattat ttggccttgg
     7081 tgtctggctt ggtctatgga tgagccagct tgaggagaaa tacaaataac actcgataca
     7141 ccagcaagta cctctaacag cagcattaag atcaaaaaaa cgaatgacta gctctcagcc
     7201 ttatcaccag ctgtgactag cattcgtttt tttatatgtc atcatgctgt cttgcctctg
     7261 tcacgatttc tataaaacgg ttcgtcaatt gagcagttat accccagata ggcttttcta
     7321 aatgctcata gagtaatacc tgatcttgca tgtacctcaa cctgtactgc tctccattag
     7381 ggatacgatc caacggaaag tctgacgaga ttatcgattg catttgtaaa ggataagcaa
     7441 caggagcttg cgccatgagc tcctccaaag gcaccgtaaa caagctatca acctcttcat
     7501 tgaccctaag ccttctccaa tcatcaatag ccagttccgc aacaaagcaa tgaatgctac
     7561 gagtcggctg aactaaatag tcaatctccc cccaaacatg aacctgctca ggctctatat
     7621 tgagctcctc taccgtctca cgaatagccg cctgctgata agtctcaccc tcctccacgc
     7681 gcccactagg aaaagaaacc tcccctggct tgaatg
//
LOCUS       DARYVE010000076         7672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYVE010000076 DARYVE010000000
VERSION     DARYVE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(171..461)
                     /locus_tag="TVW25_001749"
     CDS             complement(171..461)
                     /locus_tag="TVW25_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379356.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TVW25_001750"
     CDS             complement(442..834)
                     /locus_tag="TVW25_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379357.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TVW25_001751"
     CDS             complement(816..2105)
                     /locus_tag="TVW25_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379358.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..2538)
                     /locus_tag="TVW25_001752"
     CDS             complement(2107..2538)
                     /locus_tag="TVW25_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379359.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            complement(2759..3193)
                     /locus_tag="TVW25_001753"
     CDS             complement(2759..3193)
                     /locus_tag="TVW25_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379360.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKITEEQQKKDLETSIAKL
                     LVHDYEGVKTIKFQGWGHSRETGSWGTTVIINESNQMSFSFSSIKTLEDIGSTRYNPN
                     TFKLVEKPETDSKPRIMDRMNEINATSLAGVTVIYSNNNQED"
     gene            3532..3618
                     /locus_tag="TVW25_001754"
     CDS             3532..3618
                     /locus_tag="TVW25_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1379361.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(3966..6407)
                     /locus_tag="TVW25_001755"
     CDS             complement(3966..6407)
                     /locus_tag="TVW25_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1379362.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(6407..6868)
                     /locus_tag="TVW25_001756"
     CDS             complement(6407..6868)
                     /locus_tag="TVW25_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1379363.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(7038..7241)
                     /locus_tag="TVW25_001757"
     CDS             complement(7038..7241)
                     /locus_tag="TVW25_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1379364.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
BASE COUNT         2173 a         1801 c         1348 g         2350 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctattaga atcattaaag caataaaagc
     2521 tttggtcgac tttttcatga aagttctcct ttcaatttct aataatagta tacaataaaa
     2581 atgagtaaaa aataaagcta aacagttttt ctataatgtt atctgttata agttaaattc
     2641 tcctgctaat aatctttcca ttaaaacaat agggacatca ttaaatttag ctttccttag
     2701 ttcgatatta taggtctgtc ttgctaactc attatagcta ctatcggata tcgccatatt
     2761 aatcctcctg attgttattt gaatagataa cagtaacacc tgcaagagag gtcgcattaa
     2821 tctcgttcat cctatccata attcttggtt tagaatcagt ttcaggtttt tctaccaatt
     2881 taaaagtatt gggattatat cttgtgcttc ctatatcttc taaagttttt atactagaaa
     2941 aagaaaaact catttgatta ctctcattaa taatcaccgt cgttccccac gaacccgttt
     3001 cacgagaatg tccccatcct tgaaatttaa tggttttaac cccttcatag tcatgaacaa
     3061 gcagcttagc aatgctggtt tccaaatcct ttttttgttg ttcttctgtg attttaccat
     3121 tcaaactaaa taccataagc aaccctccta tgagaatcat taaagcaata aaagctttgg
     3181 tcgacttttt catgaaagtt ctcctttcaa tttctaataa tagtatacaa taaatcagaa
     3241 gtcatagaat aaccatattc aatttttatg tcgtattcga taaaaaatat accatctcaa
     3301 caaacaatcg cttaaaaacg attttagggt atatttcttc cctgcaagca aaggacacaa
     3361 aaaagccatc tgaattttca acatcagaca gctatttcgt atgactatgg tataatggtt
     3421 tctgcagaaa agttaaggcg gtggctctaa tttctgaaag gtggtggtgc ttatgactgt
     3481 aagtgctaaa atccaaagag aaaggagcga atattgtccg tttacgaggc aatgcaactc
     3541 atgcttgggt tcggtagttt tctactttca ctcattggct tagttgttat tatcgtaaaa
     3601 atgagcaata aaaaataacc gtctaacttt agcgagtaac ggttattttt taactaaaaa
     3661 caagctaccg tcttaaacgg ttctgcattg ggtagttgtt ttgagcaact gtcctttttc
     3721 tattttcatt atatctcagc taagaaaaat agtcaaatga gatactattt tggcagctaa
     3781 attggtagct aaatcttcaa aatacctatt tttcgctaaa ttcgattaaa attaaatcct
     3841 atctgtctgc tacgctttaa actctcactc tagtacttca tcaccatacg acaaaaagag
     3901 cctgagaaac tttttgtctc agactctctc aaagctctta gcttaatatc aagcaaagtc
     3961 atgcattaag cgatatcaaa agctagtttt ccacgtgata caccaatctt gaggctttga
     4021 ccgcttgata actctcctga cagcattaat tctgctaacc tgtcctcaac ctctgtttgc
     4081 aaggtgcgac gaagtgggcg agcgcccatt tcaacatcgt aaccagcttc agacaagtac
     4141 ttgagagctg atggctggaa cttaaggcta atatgctttt ctgccaaggc tgcaatcagc
     4201 ggcttaacca taattttcac cacatcacgc atgttttcct gtgttaggct atggaagacc
     4261 accttttcat caattctgtt gataaattca ggccgataag cctttttcaa ttcctctaaa
     4321 atacgctttt ccattgcttg atggtcatga ccgatcgctt tagcgccaaa tccaaccgtc
     4381 ttatcatctc ttagagcagt tgctcctagg ttgctcgtca tgataataat cgtgtttgaa
     4441 aaatcaacct tacatccacg actatctgtt aacataccat catcaaggac ctgcagcagg
     4501 atattaaaga tgtctgggtg agccttttca acctcatcaa aaagaagaac ggcataaggc
     4561 ttatttctaa ccttttcggt tagctctcct ccctcatcat agccaacata gccaggagga
     4621 gccccattaa gacgggaggc tgcaaatttt tccatgtact cagacatatc aaaacgaata
     4681 agggctgact catcatcaaa gagtaattcg gccaaggcct ttgctagctc tgtttttccg
     4741 acaccagttg gaccaagaaa cataaaggag ccaatcggac gcctgcctgt gcgaatgcct
     4801 gactggttac gacgaatggc tcgtgcaata gcagaaacag ccatttcctg accaacaaca
     4861 cgcttatgca attccttttc cagattcagg tattttttac tatccgcctg agttagtttt
     4921 tctaggggaa tacctgatag cttgcttaag gtgtgtaaca tatcatcttc agtaactgct
     4981 gttggtttta gctttggttg cttatcctct ttgactaaaa gggctgacac cttgctcata
     5041 tcaccatcaa gcagggcttg atcaagcggt gttataaagt caggctgcgt ctttttaacc
     5101 atactttgca ccatcgcact ggcttcatca agcagatcaa tcgctgagtc tggaagctgc
     5161 ttacttgtca aatagcgccg agccagcttc acagcagtat ggacagctgt atcagagatt
     5221 gttacattat ggtactgttc ataggaaggc ttcaagccaa gcaaaatctg ataagcgtcc
     5281 tcaacactag gctcctcaat caatatcttg gcaaagcgac gagaaagggc tgcgtccttt
     5341 tcaatgtgct tttgatattc ctcttgagtt gtagcgccaa ccatatgcag ggtaccgcga
     5401 gaaagggctg gctttagaat attagcggca tcaagtgtgc tgtcaatacc acttcctgat
     5461 cccataatgg tatgtagctc atcgacaaac aaaatgatct taccatctgc ttcaatatcg
     5521 tcaatgagtt gattcatgcg ctcttcaaaa tccccacgaa aacgggtacc tgcaaccaca
     5581 ctcatcatgt caagctccaa gacacgcatg tcttgtaatt cataaggaat ggctccatta
     5641 gcaattcgct gcgctaagcc ataagctaga gcagtttttc cgacacccgc atcaccaaca
     5701 agaacaggat tatttttcgt cttacgacaa agcacctgaa ccatacgtga cacctctttt
     5761 tctcgtccga tgactggctc taataagccc tgtcttgcca tctctgtcag gtctcttgta
     5821 aagtctgata gctcaccagc tgtactctgt ggcttcatca tttcagaaaa ggtgcctact
     5881 gatttactct ttttaggctt acgcaactca tgaatcgcct taatagtttc cttgctatag
     5941 ccggcattta gctcaatagc cttacgtaaa tccgcaaacc taggctctcc cttgccagaa
     6001 tccttgagcc tgtagcctgc caattctaac agacgactgg ccataatatc cggattgagc
     6061 aaaatagcaa agagtacatg ctctgagcca acctcatgct cattgataac ctgacagata
     6121 gcatgagcaa atgctagtat ttctgataag gccttggatt gtggcttgaa ttggacagaa
     6181 gtcacctctt tgggactttt tcccatggct aaaatagcag cagcctcata ctcttcagcc
     6241 ctaatctttc gttcaaattc gcttaacacc atggccgcta aggaatggtc aacagctacc
     6301 atagctaata aaatatgcca ggtctcaagg taaggactat caaagcgctc tgcttgaaat
     6361 tgagcctgat taaaaatgtc ttgcatcttt aatgaataaa tcatcactaa ttgcttccct
     6421 ttctatcaat tcgttgcaat aggcgataaa gcatacgagc acgaatttct ggtgcttgat
     6481 gtcccaaaac atcattagaa gctacagcta agataatgtt tccttcgcgc tctgttaaca
     6541 gttgctcatc aaaaagcagc tgaatcgaat ctgtaaaggc ctgctcgctt aaacaatcat
     6601 caatagaagc gatcaacgta ccaatcaggt ggtgcttatc cgaaaaatga accttagcaa
     6661 tacgaatgta gccaccacca ccacgcttac tttctacctc atagcctctg ctttctgtaa
     6721 aacgggtctt gatcacataa ttaatctggc ttggtactac ttgaaaggaa tccgccagca
     6781 tggagcgctt gatctctgcg attcctgatt gggctaacaa ttctttgata tattcttcga
     6841 tactatcgga agtatttttt gttggcatgc cgtcactcct ttgctaaaac gattcatttg
     6901 ctgctttaag cctttatttg actaaaactg actaacatta tatcaaatag cagtcactaa
     6961 aagcaaatgg aaatcactag aatgtaaaag gacaggtgct atcaacaaca cccatcccct
     7021 attatctgct cactagatta agacaattta gtgatattta ctgcctgagg accgcgctgt
     7081 ccgtcttcaa catcaaacgt caccctttgt ccctcgtcta acgatctaaa gccgtcagac
     7141 tggattgctg aaaaatgtgc aaaaacatct tgaccatttt cagttgaaat aaagccaaag
     7201 cccttttcag cattaaacca cttgactgta ccttgtgcca tagtcatcca cttcctttct
     7261 ataacgcatt tgtaaacata gagagaaata aagatgccaa aacacaacta ctaattcaaa
     7321 aactaattta ctcgctcagt gtaacacgaa tggcagccac tgtcaacaca tacccctcac
     7381 aatgacagct tttctactcc acctgctaaa atgtaaaaaa gcaaagtcat gctgaccttg
     7441 ctttaacaat ctaaggcggt agacggattt tagatgcatt gatatcagtg ctttagagta
     7501 actttgaccg acttttgacc gaccgccaat ctaactccct cagcacattt tctacttttt
     7561 cctcggtcac cacttcccaa ggctgcactt tctcccctgg caacacataa tcaaatatct
     7621 gtccgttttt acgcacaatc gctactgtgt ctcctgttat atatccgtca tc
//
LOCUS       DARYVE010000077         7596 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYVE010000077 DARYVE010000000
VERSION     DARYVE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            56..3622
                     /gene="rpoB"
                     /locus_tag="TVW25_001758"
     CDS             56..3622
                     /gene="rpoB"
                     /locus_tag="TVW25_001758"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1379365.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            3713..7348
                     /gene="rpoC"
                     /locus_tag="TVW25_001759"
     CDS             3713..7348
                     /gene="rpoC"
                     /locus_tag="TVW25_001759"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1379366.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(7440..7596)
                     /locus_tag="TVW25_001760"
                     /pseudo
     CDS             complement(7440..7596)
                     /locus_tag="TVW25_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2044 a         1518 c         1907 g         2127 t
ORIGIN      
        1 atgttgcaat tgtttgcttg atagcaaagc ttaaaaagaa aaaggagcta aaaacttggc
       61 aggacatgac gttcaatacg ggaaacatcg tacccgtcgt agtttttcaa gaatcaaaga
      121 ggttcttgat ttaccaaatt tgattgaaat tcaaactgat tcattccaag atttcttaga
      181 ttcaggcttg aaggaagtat ttgaagatgt gcttccaatc tcaaacttta cagacacgat
      241 ggagcttgag tttgttggtt acgaatttaa ggagcctaaa tatacccttg aagaggctcg
      301 tatccatgat gcaagctatt ctgcaccaat ctttgtgacc ttccgcctga ttaataagga
      361 aactggcgaa atcaaaacac aagaggtctt ttttggtgat tttccgatta tgactgaaat
      421 gggaaccttt atcatcaacg gtggagagcg tattattgtt tctcagctgg ttcggtctcc
      481 tggtgtttat ttcaatgaca aggttgataa aaatggtaag gttggttatg gctcaacagt
      541 tatccctaat cgtggtgctt ggctagagct agaaactgac tcaaaggata ttgcttatac
      601 tcgtattgac cgtacgcgta aaatcccatt tacaacgcta gtgcgtgcac ttggtttttc
      661 tggtgatgac gaaattattg atatttttgg tgatagtgag cttgttcgca ataccattga
      721 aaaggatatt cataaaaacc aaagcgattc acgtacagat gaggctctta aggaaattta
      781 tgaacgctta agaccaggtg agccaaagac agctgatagc tcacgcagcc ttttgacagc
      841 tcgtttcttt gatgctcgcc gttatgactt ggcagcagtt ggccgttata agattaataa
      901 aaagctgaac atcaagacac gtcttttgaa tcaaattatt gctgaaaatc taatagatag
      961 tgagactgga gagattctgg ttgaggctgg aacagagatg actcgtagtg tgattgagtc
     1021 aatcgaagag cagcttgatg gggatttgaa caagtttgtc tacacaccaa acgattatgc
     1081 ggtggtgaca gagcctgtga tcctacaaaa attcaaggtg gtttcaccag ttgatcctga
     1141 tcgtgtggtg acgatcgttg gtaatgctaa cccagatgat aaggttcgtg cccttactcc
     1201 ggctgatatt ttggctgaga tgtcttattt ccttaacctt gctgaaggtc ttggaaaggt
     1261 cgatgacatt gaccacttag gtaatcgtcg tatccgtgca gttggtgaat tgcttgctaa
     1321 ccaattccgt attggtcttg ctcgtatgga gcgcaatgtc cgcgagcgta tgtctgtaca
     1381 ggataacgat gtgttgactc cacaacagat tattaacatt cgtcctgtaa cggcggctgt
     1441 caaagaattc tttggttctt cacagctatc acagttcatg gatcagcaca acccattgtc
     1501 tgagttgtcg cacaaacgtc gtttgtctgc cttaggacct ggtggtttga cacgtgatcg
     1561 tgctggctat gaggtgcgtg acgtgcacta cactcactat ggtcgtatgt gtccgattga
     1621 aacacctgaa gggccaaata tcggtttgat taataacctg tcttcatttg gacatctgaa
     1681 caaatacggc tttattcaaa ccccttaccg taaggttgat cgtgtgattg gccgagtgac
     1741 taatgagatt gtttggctaa ctgctgatga agaggatgag tttacagtgg ctcaggctaa
     1801 ttctaagctc aatccagacg gtacctttgc tgaagagatt gtcatgggac gtcaccaagg
     1861 taataaccaa gagtttcctg ctagtcaggt tgactttgtt gacgtgtctc ctaagcaggt
     1921 agtcgctgtt gcgacagcat gtattccttt ccttgaaaac gatgactcca accgcgccct
     1981 aatgggagct aacatgcagc gtcaggctgt gccattgatt gatccaaagg ctccttatgt
     2041 tggtacgggt atggaatatc aagcagctca tgattcaggt gctgcggtaa ttgcccagca
     2101 taatggtaag gttgtctttt cagatgctga aagagtagag gtgcgtcgtg aggacggttc
     2161 acttgatgtt taccacatca caaaattccg ccgttcaaac tctggtactg cctacaacca
     2221 acgaaccctt gttaaaatag gtgatattgt tgaaaagggt gactttatcg ctgatggccc
     2281 ttctatggaa aaaggtgaga tggctcttgg tcaaaatcca atcgttgctt acatgacctg
     2341 ggaagggtac aactttgagg acgcggttat catgagtgag cgtcttgtga aggaggacgt
     2401 ttatacctct gttcacttgg aggagtttga atcagaaaca cgcgacacaa agcttggacc
     2461 tgaggaaatc acacgtgaag tgccaaacgt tggtgaagaa gccctcaagg accttgatga
     2521 aatgggtatt atccgtatcg gtgcagaggt caaggaaggc gatattcttg ttggtaaggt
     2581 aactcctaag ggtgaaaaag acctttctgc tgaagaacgt ctcctgcatg ctatctttgg
     2641 tgataaatca cgtgaggttc gtgatacctc gttacgtgtt cctcatggtg gtgacgggat
     2701 tgtacgtgat gtgaagatct ttacacgcgc aaatggtgat gagcttcaat caggtgttaa
     2761 tatgctggtg cgtgtttaca ttgctcaaaa gcgtaaaatc aaggtcggag ataaaatggc
     2821 cgggcgtcat ggtaacaagg gtgtcgtctc acgtattgta ccggttgagg atatgccata
     2881 tctgccagac ggaacccctg ttgacatcat gctgaaccct cttggggtgc cgtctcgtat
     2941 gaacattgga caggttatgg agcttcacct aggtatggct gctcgtaatt tgggtatcca
     3001 tatcgcaaca ccggtctttg acggagctac gtctgaggac ctttgggaaa ctgttcgtga
     3061 agcaggtatg gatagcgatg ctaagactgt tctttatgat ggccgtactg gtgagccgtt
     3121 tgataatcgt gtgtcagttg gtgtcatgta tatgattaag cttcaccaca tggttgatga
     3181 taagcttcac gcgcgttctg taggaccata ctcactggtt acccaacagc cgcttggagg
     3241 taaagctcag tttggtggcc aacgttttgg tgagatggag gtatgggctc ttgaggctta
     3301 tggtgcttca aacgttcttc aggaaatctt gacctataag tcagacgatg tgaatggtcg
     3361 cttgaaagct tatgaggcga ttaccaaagg taagccaatt ccaaagcctg gtgtaccaga
     3421 atctttccgc gttcttgtga aagaattgca atcacttggt cttgatatgc gtgtccttga
     3481 tgaagacgat aatgaagttg agcttcgtga tcttgatgaa ggcgaagacg atgacgtgat
     3541 gcacgttgac gatcttgaaa aagcgcgtga aaagcaggct caggaaactc aagatattgc
     3601 tgaatcaact gaagacaact aaatcataaa catttgtaac agaaataatg actagactag
     3661 ggctatttgc cctagctgct agtaagtcat caaaggcaga aaggtaaaac tagtggttga
     3721 cgtaaatcgt tttaaaagta tgcaaatcac attagcttca ccaagtaagg tccgttcatg
     3781 gtcctatggt gaagttaaaa aacctgaaac aatcaactac cgtacattaa aaccagaacg
     3841 tgagggtctt tttgacgaag tcatttttgg accaaccaag gattgggagt gtgcgtgtgg
     3901 caaatataaa cgtattcgct ataagggcat tgtctgtgac cgttgtgggg tcgaggtaac
     3961 gcgtgcaaag gttcgtcgtg aacgcatggg acacattgag ctgaaggcac ctgtctcaca
     4021 tatctggtat tttaagggaa tcccatctcg tatgggcttg actcttgata tgagtcctcg
     4081 tgctcttgag gaggtaatct attttgcggc ttatgtggtt attgatccaa aggacacacc
     4141 gcttgagcca aaatcactat tgacagagcg tgaatatcgt gaaaaaatcc aagaatatgg
     4201 acatggctca ttcattgcta aaatgggggc agaggctatt caagacctcc taaagcgtgt
     4261 tgatttggtc acagaaattg ctgagctaaa ggaagaatta aaaacagcaa caggccaaaa
     4321 gcgtatcaag gctgttcgtc ggttagatgt gcttgatgcc tttcataaat caggcaataa
     4381 gccagaatgg atgatcctga acatcttgcc ggtcattcca ccagatcttc gtcctatggt
     4441 gcaattggac ggtggccgct ttgcagcctc agacttgaat gacctttacc gtcgtgtcat
     4501 taaccgtaat aatcgtttag cacgtttgtt ggagcttaat gcgcctggta tcattgtgca
     4561 aaatgaaaag cgtatgctgc aagaggcggt tgatgctttg attgataatg gtcgtcgtgg
     4621 tcgtcctatt acaggacctg gtagtcgtcc gcttaaatcc ttgagccaca tgcttaaagg
     4681 aaaacaaggg cgttttcgtc aaaacctgct tgggaagcgt gttgacttct caggtcgttc
     4741 agttattgct gtgggtccaa cgctaaaaat gtaccaatgt ggtgtaccac gtgagatggc
     4801 tattgagctt ttcaagccat ttgtgatacg tgagattgtt gcccgcgaat ttgccggcaa
     4861 cgtcaaagca gctaagcgta tggttgagcg tggcgatgag cgtatctggg atattctaga
     4921 agaggttatc aaggagcatc cagtcctgct taaccgcgca cctacccttc acagattagg
     4981 gattcaggcc tttgagccgg tgcttattga tggtaaggct cttcgtcttc acccgcttgt
     5041 gtgtgaggcc tacaatgccg actttgacgg agaccaaatg gctattcacg tgccgctttc
     5101 agaggaagca caggcagagg ctcgtttgtt gatgcttgct gctgagcata ttcttaaccc
     5161 taaggacggt aagccagttg taacaccttc tcaggatatg gtgctaggaa actactacct
     5221 aacaatggaa gatgctggtc gtgaaggcga aggtatggtc tttaaggaca aggacgaagc
     5281 ggtaatggct taccgtaatg gctatgttca ccttcatagt cgtgttggta ttgctgttga
     5341 cagtatgcca agcaagcttt ggaaggatag tcaaagacac aaaatcatgg tgacaacggt
     5401 cggtaagatc ttgtttaatg acatcatgcc agaggacctt ccttacctcc aagagccaaa
     5461 taatgctaac ttgacagagg gcactccaga taaatatttc ttgaagccag gtcagaatat
     5521 tcaggaggtt attgatagct taccgatcaa tgtgcccttc aagaagaaaa atcttggtaa
     5581 catcattgcg gaaaccttca agcgtttccg tacaacagaa acatcggcct ttcttgaccg
     5641 cttgaaggac cttggctact atcattcaac ccttgcgggc ttgacggttg ggatcgctga
     5701 tattccggtt attgacaaca aggctgagat catcgaggct gctcaccatc gtgttgagga
     5761 aattaataag gccttccgtc gaggcttgat gactgatgat gatcgctatg ttgcagtcac
     5821 aacaacatgg cgcgaggcaa aagaagccct tgagaagcgt ctgattgaaa cacaggatcc
     5881 taagaaccca atcgttatga tgatggactc aggagcgcgt ggtaacatct ctaacttctc
     5941 gcagcttgcc ggtatgcgtg gcttgatggc tgctcctaat ggccgtatta tggagcttcc
     6001 tatcctgtct aacttccgcg aaggcttgtc tgttttggaa atgttcttct caactcatgg
     6061 tgctcgtaag ggtatgactg atacggctct taagacagct gactcaggct atctgacacg
     6121 tcgtttagtt gatgttgcgc aagatgtcat cattcgtgag gacgattgtg gtacagaccg
     6181 aggccttctt attcgagcta tcacagatgg caaggaagtc actgaaacac ttgaggagcg
     6241 cttgcagggt cgatacactc gtaaatcagt caagcaccct gaaactggtg aggtattgat
     6301 tggtgctgac caattaatca ctgaggacat ggctcgcaag attgttgatg ctggtgttga
     6361 agaggttacc attcgctcag tatttacctg tgctactcgt catggagtgt gtcgtcactg
     6421 ttacggtatc aacctagcga caggtgatgc ggttgaggtt ggtgaggctg ttggtactat
     6481 cgctgcccaa tctattggtg agcctggtac tcagctgacc atgcgtacct tccacacagg
     6541 aggggttgcc tctaataccg atatcacaca gggtcttcct cgtatccaag aaatctttga
     6601 agcgcgcaac cctaaagggg aagcagttat cacagaggtt aaggggactg ttattgagat
     6661 tgaagaggac gcatcaactc gtactaagaa ggtctacgtt caaggtaaaa caggcatggg
     6721 tgaatatgtt gtgccattta cagcgcgtat gaaggttgag gttggtgatg aggtcaatcg
     6781 tggagctgcc cttacagaag ggtcaatcca gcctaagcac ctccttgagg ttcgtgatac
     6841 cttgtcagtt gagacctact tgcttgctga ggttcaaaag gtttaccgca gccaaggggt
     6901 agaaatcgga gacaagcacg ttgaggttat ggttcgtcaa atgcttcgca aggtacgtgt
     6961 catggatcca ggtgatacag atcttctgcc aggaacctta atggatattg cagactttac
     7021 agatgccaat aaggagattg ttatctctgg aggtattcct gcgacctctc gtccagtgct
     7081 tatgggaatc acaaaagcct cacttgagac taactcattc ctatcagcag cttccttcca
     7141 ggaaaccact cgcgtgctga cagacgctgc tatccgaggc aaaaaagacc atctattggg
     7201 gcttaaggaa aatgttatca ttggtaagat cattccagca ggtactggta tggttcgtta
     7261 ccgtaacatt gaaccgcaag ctatcaatga ggttgaggtt atcgaagaag ctgaagctac
     7321 agaagagcca gcaattatta aggaataaga aataaaagga gctagcctta gctcctttta
     7381 tcatgctaaa atcattagat taattgggct ccatgtcaac tatagtaggt gactgataac
     7441 taagcacgag aggagacgaa ggtcgtcttc tcttttgtca tgttcaaagc aagcatagat
     7501 aagtttcttg aaattgtcaa cgtttctgaa tccaaatgca ttgcgcttga tgtctttgat
     7561 cagtttgcta gtcgcttcaa acttggcgtt agaata
//
LOCUS       DARYVE010000078         7527 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYVE010000078 DARYVE010000000
VERSION     DARYVE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7527
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(209..424)
                     /locus_tag="TVW25_001761"
     CDS             complement(209..424)
                     /locus_tag="TVW25_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379367.1"
                     /translation="MVDKYIPGRYIQREIDEIIELVRDRSKFEPVRVREVQEHIQKIL
                     IQHEAEILARLEENQDQKASENSNDIF"
     gene            613..903
                     /locus_tag="TVW25_001762"
     CDS             613..903
                     /locus_tag="TVW25_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379368.1"
                     /translation="MAIEVFGPDFRKELLADLISLNREALKIAQFENSKSIEWVTMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGA"
     gene            905..1099
                     /locus_tag="TVW25_001763"
     CDS             905..1099
                     /locus_tag="TVW25_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379369.1"
                     /translation="MNKLELFLLAATVILAIIARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKRWSEKRSRGEVEKCLL"
     gene            1234..1413
                     /locus_tag="TVW25_001764"
     CDS             1234..1413
                     /locus_tag="TVW25_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379370.1"
                     /translation="MTTTKKLGRPTSNPKSHSKRLRMTDEEVQKLEYCTKQTGKTQTD
                     VLMLGLDKVYQELKK"
     gene            1586..1858
                     /locus_tag="TVW25_001765"
     CDS             1586..1858
                     /locus_tag="TVW25_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379371.1"
                     /translation="MDNSKLANHQKVTVVCTDFNVYLNGIRLTGARPETAKLAERCGE
                     KLITLSLVVTDFDDHRTPKMADMAKEAEMANKTLDWEKKHFYKSNK"
     gene            complement(1848..2228)
                     /locus_tag="TVW25_001766"
     CDS             complement(1848..2228)
                     /locus_tag="TVW25_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379372.1"
                     /translation="MIDYYSLYKNSLEAIGYHKLDTGVDLLQYLIATEEGKRIYSQYP
                     YREVEEIIFYTLDCLIQQDLVTATEMPRLDRRIYTIDGLTPKGMYFLGYIGQVETEVI
                     EWLNEFGVSQNPESIYNALRYIIY"
     gene            2284..2727
                     /locus_tag="TVW25_001767"
     CDS             2284..2727
                     /locus_tag="TVW25_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379373.1"
                     /translation="MAKTYTLTEEELNELVAERMKQAKEKRTPQGLFKDVSFDDELIP
                     INEKYPKVLKKLNRERAYKPEKHVFNQTPKVFGVDNDISYSKITTHDVHNHIRLLVLN
                     VFGKSQNKEVLPEEYDQAIELYKELKEWFVSSYDKRLEGLVLEDD"
     gene            2844..3656
                     /locus_tag="TVW25_001768"
     CDS             2844..3656
                     /locus_tag="TVW25_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1379374.1"
                     /translation="MGKEKTKIYFWLKFDKKFFENIFIKRLKKMAGGDTMTVLYIRLM
                     LESLETDCILYYEGYFENLVEELAIKLEVSEDDINMTLAYFTKCGLIQIDGSGNAQMP
                     QAKAMLESETNWAKYKRETRKIGQIPTNVQPMSNQCPTEIEIEKDKKKDINIDIKSEV
                     EEEIKEISTADENSLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVKSAITRA
                     ADNSKRSFGYVNSILRNWRQNGITTMVKVKEESRNFKARKAKQEEVSEYDTW"
     gene            3643..4425
                     /locus_tag="TVW25_001769"
     CDS             3643..4425
                     /locus_tag="TVW25_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1379375.1"
                     /translation="MTLGDNNALAKIAVAYQKNVKKESTVCQKHGCIYITILKTGLTV
                     CPMCHKEDLESQNELHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRVITPKQ
                     QEVLSWAKSMANYWYTGGKGNIIMTGKAGRGKSHLAYSIIRGLSDETKKLGLLVNITD
                     LLSEIKRDFSQEAFWLDKLKNVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPVEIRKNYGERIASRIRKGCAKSHIMDFAGLEDERIKLWN"
     gene            4562..4768
                     /locus_tag="TVW25_001770"
     CDS             4562..4768
                     /locus_tag="TVW25_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379376.1"
                     /translation="MTPEEAEKAKIRAKQEIEVFSIYLEQAIDTFGSMLSPQEVFLAA
                     GFAYLGAGQTDIHAAVEGLYEQVR"
     gene            4930..5856
                     /locus_tag="TVW25_001771"
     CDS             4930..5856
                     /locus_tag="TVW25_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEL1379377.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SKSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIDEDNQDST
                     ISIPKDITPPETNSLDDLIGHQNEKKDAPGNLKDVTDDLHSEPEKTLTDENKTVLEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLI"
     gene            5853..6053
                     /locus_tag="TVW25_001772"
     CDS             5853..6053
                     /locus_tag="TVW25_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379378.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREECVFYDTPIDEVIKRLLDD"
     gene            6046..6843
                     /locus_tag="TVW25_001773"
     CDS             6046..6843
                     /locus_tag="TVW25_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1379379.1"
                     /translation="MTSLDLLGKDYYSKESAIRYWSISQYKRFRECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFEGEEAHEEFKVQNSSEMISTRGTTKGQLKKDYLVAEQMI
                     DALKSDNNFMAIYQGEKEVAITGFLGEVEFKGKIDCLNAERGYFVDIKTTKGPIDDKI
                     WNGQERVYWFEAYSYILQMAAYKNMLEAKHKKPFEPIIYAVTKETPPDTRAIRIQNLD
                     AMQNELDNLAQNIKRLDDVKKGIEKSKPCGHCEYCRANQLTQRVMIF"
     gene            7022..7363
                     /locus_tag="TVW25_001774"
     CDS             7022..7363
                     /locus_tag="TVW25_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379380.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGGLTMQWDFISDFKKIDDE
                     PSLDEDGELFEVAYDLVLEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
BASE COUNT         2773 a         1244 c         1521 g         1989 t
ORIGIN      
        1 gggcagcagt attttatcaa caaatttctt aaccaggaat atctgccagt ttagaaagga
       61 aaccacatga gaccaaaacg atatccgtat acaccaaaaa gaccctttcc gagtcaagaa
      121 agagtcgcaa gttatagatt ggctattgaa gagttaaatt ctttagcacc aacagcatcc
      181 gaaacactaa agaaaaaaat agaagaagct aaaaaatatc atttgagttt tctgaagcct
      241 tttgatcttg attttcttct aaacgagcaa gaatctcagc ttcatgttga ataagaattt
      301 tttgaatatg ttcctggact tcacgaactc taactggttc gaacttactt ctatcacgaa
      361 ccaattcaat aatttcgtcg atttctcttt gaatataacg accaggaata tatttatcaa
      421 ccatgtaatt tatcctcctt tatagcatat ttgactaacg acttcataag gaatagatgg
      481 tttgtcataa atcaattata gcagaaagag ggggcataga agaatttata tacaacaaaa
      541 aagtccgacg ggaatcggac tcaaaacaaa aactatttac ttagattata acacaagaga
      601 gaggaaggtt ccatggcaat tgaggtattt ggaccagatt tcagaaagga actacttgca
      661 gacttgattt ctctaaacag agaagcgcta aaaattgctc aattcgagaa ctctaagtca
      721 attgagtggg ttaccatgaa gcggttggaa aaagaaactg gatgggggcg aactaaattg
      781 acccagtgga gagaacaagg gaaatttaac tttaaaaggt catcagaaaa cgggaaagta
      841 ctatatgacc tagcagatgt taatagattt ttgcgaacaa gtggatatga aaaaggagca
      901 taacatgaac aaactagaat tatttttatt agcagcaacc gtcatcttag caatcattgc
      961 aagaattcag tatgaagtca taaaaaaaca taattcgccc gaaaataagc gaaaaatttt
     1021 tagggaagta gctttagaaa acagcaaaag atggagcgag aagcgctcta gaggagaggt
     1081 agaaaaatgc cttttgtaaa acggtagaaa ccacatagtc ctttgacaac tgaatagggt
     1141 accttgaaaa aatattaaaa aagtttgatt ttggggttga cttatgtatc cacataatga
     1201 tattatatat ttgtggatac gaaaggagga aatatgacca ctaccaaaaa acttggtcgt
     1261 ccaacttcta atcctaagtc tcatagcaaa agactgagaa tgacagacga agaagtacaa
     1321 aaattagaat attgtactaa acaaactgga aaaactcaga cagatgtttt gatgctaggc
     1381 ttagataagg tctatcaaga gctaaaaaaa tagcgtataa tccgccatcg ccaaactttg
     1441 gattacacgc tatcgaccga cctgaaaaca ggtacacaaa tatattatca tgtgtaccct
     1501 tttcagtcaa cctgacaagg gtattttttg cgcccttgtt gtttagataa gggtttttat
     1561 tgtacccaaa aataggagga acacaatgga taattcaaaa ctagcaaatc atcaaaaagt
     1621 aacggtagtc tgtacagatt ttaatgtcta tttgaatgga atacgactta ctggagctag
     1681 accagaaacc gctaaattag ctgagagatg cggagagaaa ctcattacac taagtctagt
     1741 agttacagat tttgatgacc atagaacacc taagatggcg gatatggcaa aggaggctga
     1801 gatggctaat aaaacattgg actgggagaa aaagcatttc tataaatcta ataaataatg
     1861 tatctcagag cgttatagat tgattctgga ttttgcgaaa ctccaaattc attaagccat
     1921 tcgataacct cggtttctac ctgcccgata tatccaagaa aatacatgcc ttttggtgtc
     1981 agaccgtcaa ttgtatatat tcgtctatct aatctcggca tttctgtggc agtaactaaa
     2041 tcttgttgga tcaaacaatc tagggtgtaa aaaataattt cttcaacttc tcgataaggg
     2101 tattgagaat atatcctttt tccttcttct gttgcaataa ggtattgaag taaatctaca
     2161 cccgtatcca acttatgata tccgatggct tcaagtgaat ttttgtataa agaatagtaa
     2221 tcaatcatac acttctccaa gtattttatt ttaaatataa caaaatagta agaggaaaac
     2281 aatatggcta aaacttacac attaaccgaa gaagaattga atgaattagt agctgagcgc
     2341 atgaaacaag cgaaagaaaa acgcacacca caaggactat tcaaagatgt cagctttgat
     2401 gatgagttga ttccaatcaa tgaaaaatat ccaaaagtac tcaagaaatt aaatcgtgaa
     2461 cgtgcttata aaccagaaaa acacgtcttc aatcagacac caaaagtttt tggtgtggac
     2521 aacgatatta gttatagcaa aattacaaca catgacgtac acaaccatat tcgtttgctt
     2581 gtcctaaatg tctttggtaa aagtcaaaat aaggaagtat tgcccgagga atatgaccaa
     2641 gcaatagagc tttacaagga attgaaagaa tggtttgtgt ctagctatga taagcgatta
     2701 gagggattgg tgctagaaga tgattaaaaa attctgcgtt aactacttac taagacagat
     2761 taacaaaagc aaactagaaa caagagataa agcgaagtta aaccacttta tcacactagt
     2821 ggactacaag ttaggaggat aaattgggta aagaaaaaac taaaatatac ttttggctaa
     2881 agttcgacaa gaagtttttt gaaaatattt ttatcaaacg tttaaaaaag atggctggcg
     2941 gagacactat gacagtcttg tatattcgtt tgatgctaga aagtttagaa acagactgca
     3001 ttttatatta cgaaggatac tttgaaaatt tggtagaaga gcttgccatc aagttagagg
     3061 tgtctgaaga cgatatcaat atgacattag cttacttcac aaaatgtggt ctaatccaga
     3121 tagacggtag cggtaacgca caaatgcccc aagctaaagc tatgctggaa agtgagacga
     3181 actgggcaaa atataaacga gaaactagaa aaattggaca aattccaacc aatgtccaac
     3241 caatgtccaa ccaatgtcca acagagatag agatagagaa agataaaaag aaagatataa
     3301 atatagatat aaagtcagaa gtagaagaag agataaaaga gatttctact gctgacgaaa
     3361 acagtctcaa aattatatct gattatttcc aacaagaaat cggtattttg tctccaaatc
     3421 agtttgagca gctgtcagac tatattacca ttacaaaaat ggaggtagat gttgttaagt
     3481 ctgctattac aagagctgct gacaattcta aacgttcttt tggttatgtt aactctatac
     3541 tgcgcaattg gcgacaaaat ggaatcacca caatggtaaa agtgaaagaa gaaagtagga
     3601 attttaaagc cagaaaagct aagcaagaag aggtctcaga atatgacact tggtgacaac
     3661 aacgcacttg ctaaaatcgc tgtagcttat caaaaaaatg tcaaaaaaga aagcactgtt
     3721 tgtcaaaaac atggttgcat ctatatcaca atccttaaaa ctggattgac agtatgtccg
     3781 atgtgtcaca aagaggactt agaaagccaa aatgagttac acgtccaaaa gcaatatgag
     3841 agagagcttg aaaacaagcg actgtactat ctcaaaaaat tatcaattat ggacgacgag
     3901 ttggaaaatg cctcatttga taatttcagg gtgatcacac ctaagcagca agaggtcctt
     3961 tcgtgggcaa aatccatggc taattactgg tatacaggag gcaaaggcaa tatcatcatg
     4021 actggtaaag ctggccgcgg gaaaagccat ctagcataca gcatcatcag aggtttgtct
     4081 gacgagacta aaaagttagg gctgcttgta aacattactg acttgctatc agagataaag
     4141 cgagacttta gccaagaggc attttggcta gataagctaa aaaatgttga ttatttggtt
     4201 ttagatgact taggcgccga aaaggtcagc gactggtcca caagtattat ttacagctta
     4261 ctaaataagc gtacaaatac aatcattact acaaacttaa cacctgttga aataaggaaa
     4321 aattatggag aacgtatcgc atcaagaatt agaaaaggct gcgctaagag ccatattatg
     4381 gattttgcag gactggaaga tgagaggatc aagctatgga actaatatta ataacttttt
     4441 ttggcctatc tgaagaacat gcagccaaaa tcatggcgct agacgaagat agccgaataa
     4501 ataaaatcga ggaattgaga gcatggagag aatgctcaaa aataacattt taggaggaaa
     4561 tatgacacca gaagaagcag aaaaagcaaa aatcagagct aaacaagaaa ttgaagtttt
     4621 tagcatatac cttgaacagg cgattgatac ttttggcagc atgctaagcc cacaagaagt
     4681 cttcttggca gcagggtttg cctaccttgg cgctggtcaa acagacatac atgcggccgt
     4741 cgaggggttg tatgagcaag ttcgatgact ttaaatttag cgaagactgg gagagtaact
     4801 actttgaggt ccaagctttg ctaggacaag agatagacaa gctacaaaat agagttgtcc
     4861 agttagcaaa cgaaaataat agattaaagg ccgaaaattg gcagttaaga cacagaaaga
     4921 ggaaatgaaa tggcgaatca attatcaaca tacacacaca aacaattttt taatgcacca
     4981 acaattcaaa aggcttttga tgacgtttgg aaaggcgccg ggacacagtt cgcagtaagc
     5041 atcttgtcag tactacaagg tagtaaaagt ttgaaatcgg catctaatga atctatttat
     5101 gcagcagcta tgaaagcagc cgtgttaaat ctgcctattg agccaagctt aggaagggcc
     5161 tatttagttc cgtacaaagg tcaagcacaa ttccaattag gctataaagg gttgattgag
     5221 ttagcgcagc gcagcggaca atacaaaaat attaatgcag gtatcgtcta taaatcacaa
     5281 ttaatttctt acaacccttt gtttgaggaa ttgatccttg actttagtaa gccacaagat
     5341 gaaattgtag ggtattttgc cgcttttaaa cttttaaatg gattcgagaa agtttctttt
     5401 tggacagtag aaaaagtaac tgcacatgga aagaaatttt caaaatcgtt tgctagcggc
     5461 ccttggaaaa cagactttga tgcaatggct caaaaaacta ttttaaaaga tattttgagt
     5521 aaatatggtc cgttatcagt tgagatgcag aaagctatcg atgaagacaa tcaagattca
     5581 acaatttcta ttccgaaaga cattacacca ccagaaacaa acagccttga cgacctaatt
     5641 ggtcaccaga acgaaaaaaa ggacgctcct ggcaatttaa aagacgtaac tgatgattta
     5701 cattccgagc cagaaaaaac gctcacagac gaaaataaga cggttttaga agacacctct
     5761 tatccagctg atgaaatccc tgattttgac caagaaacag gcgaaattaa agctagcgaa
     5821 ggcaacctct ttgataatct tggagactta atatgattaa acttgtaaaa attgaaggat
     5881 attatattaa tccagaatat gttgttggcg tttgggaaag atctgcttta aattttgacg
     5941 atttagatga aaaagtagtg gttattcaat tcgttggaga tagggaaagg gaagagtgtg
     6001 tcttttacga tacacctatt gatgaagtaa ttaagaggtt gctagatgac tagtttagac
     6061 ttacttggaa aggactatta tagcaaggaa tcagctataa gatactggtc cattagtcag
     6121 tacaagcgct ttagagaatg cgaggcaagg gcacttgctg aattacgagg ggattggaca
     6181 gataccagag ataacactgc gttgctcgtc gggaattacg tccactctta ctttgagggt
     6241 gaggaggctc acgaagaatt taaagtccaa aacagttctg aaatgatttc gaccagagga
     6301 acgacaaaag gccaattaaa aaaggattac ttagtcgctg agcagatgat tgacgctctt
     6361 aaaagcgata acaacttcat ggcaatctac caaggagaaa aggaagttgc catcacagga
     6421 tttcttggtg aggttgagtt taaaggtaag attgactgtc tgaatgctga acgtggctat
     6481 tttgtagaca ttaaaacaac aaaaggacct attgatgaca aaatttggaa tggtcaagag
     6541 cgagtttact ggtttgaggc ttacagctat attttgcaga tggctgccta caaaaacatg
     6601 ctagaggcaa aacacaaaaa gccgtttgag cctatcattt acgcagtaac aaaggaaaca
     6661 ccgccagata ccagagcaat caggattcaa aatttagatg ctatgcaaaa tgagttagac
     6721 aacctagctc aaaacatcaa gcgtttagat gatgttaaaa aaggcataga aaaatctaag
     6781 ccttgtggtc attgcgagta ttgcagggca aatcaattaa cacaaagggt aatgattttt
     6841 taactaacta ttgcaaagtg aagctcggcc tttgcaataa tcatattttc cgagcgagaa
     6901 aggaaaattg caatatcgtc aagttaacag tattgatgat ataaagagtt gctacactcg
     6961 tccttgccaa tgctcacaca caattttagg gcgagtgtgg attttaaaaa aggtgaaaaa
     7021 tatggaacaa attaaaatta caggaacagg aacagcacta attttagata gagtaaaccg
     7081 aatctttgcc atctctggcg gtttgactat gcaatgggat tttattagtg attttaaaaa
     7141 gattgacgac gaaccgtcac ttgatgaaga tggagaacta ttcgaagtag cttacgacct
     7201 tgtgcttgaa gctaaaccca aaactaaaat caatctaaca tcatcatatt ttgctaaaga
     7261 gcataagaaa gacacagacg aaattataaa agtattctcg tttatcgaag ataataagag
     7321 aaatatcttt gaaacccttg gcattcgtgg ggtgcttgaa tgagcaatct agtattatcg
     7381 ctagacatct caacttctgg tacaggttgg gccttattta aaggctcaga ccttatccag
     7441 agtggtgtct taaaacataa gagcgactct tatttcgaac gtggacgata tatggctagc
     7501 caattaagag ctatccagtc acgagca
//
LOCUS       DARYVE010000079         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYVE010000079 DARYVE010000000
VERSION     DARYVE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            436..975
                     /locus_tag="TVW25_001775"
     CDS             436..975
                     /locus_tag="TVW25_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379381.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TVW25_001776"
     CDS             972..2087
                     /locus_tag="TVW25_001776"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1379382.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGKYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TVW25_001777"
     CDS             2077..3339
                     /locus_tag="TVW25_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1379383.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TVW25_001778"
     CDS             3385..4404
                     /locus_tag="TVW25_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1379384.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TVW25_001779"
     CDS             4603..5313
                     /locus_tag="TVW25_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1379385.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TVW25_001780"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TVW25_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1379386.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TVW25_001781"
     CDS             6662..7471
                     /locus_tag="TVW25_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1379387.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2020 a         1599 c         1798 g         2078 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaaag tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt acaggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYVE010000080         7414 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYVE010000080 DARYVE010000000
VERSION     DARYVE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7414
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            134..1258
                     /locus_tag="TVW25_001782"
     CDS             134..1258
                     /locus_tag="TVW25_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1379388.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(1420..2013)
                     /locus_tag="TVW25_001783"
                     /pseudo
     CDS             complement(1420..2013)
                     /locus_tag="TVW25_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            2082..4055
                     /locus_tag="TVW25_001784"
     CDS             2082..4055
                     /locus_tag="TVW25_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1379389.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            4079..5521
                     /locus_tag="TVW25_001785"
     CDS             4079..5521
                     /locus_tag="TVW25_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1379390.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            5602..6411
                     /locus_tag="TVW25_001786"
     CDS             5602..6411
                     /locus_tag="TVW25_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1379391.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            6726..>7414
                     /locus_tag="TVW25_001787"
     CDS             6726..>7414
                     /locus_tag="TVW25_001787"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679404.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1379392.1"
                     /translation="MKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVVE
                     VWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHEF
                     RKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINRF
                     LSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKLL
                     DAYINGYGYIH"
BASE COUNT         2483 a         1450 c         1600 g         1881 t
ORIGIN      
        1 taaaaaaaca gaaataaaaa aaaaacggtt taatattgac ctaattggca ataacgttta
       61 caataaaggt ataattatct gccgttgata attaggagac atcatgtcta gataaaaaca
      121 aaaggggaat aaaatggcaa aaaaagaaat gaagttttac cttcgtaaat cagcctttgg
      181 gctagcttca gtatcagcag ccctcttggt tggtgcggca gctgtatcag cagattctgt
      241 tgagtcagct gggcctgtag cagttgctgt tacagatagt ttagatagtg aagccgcagc
      301 tacaaaggca gaagctgatc tagttgctgc aaaagcagac ctagcagcag cagaagtagc
      361 aatcacagct gcaaaagctg aatttgacac cgctcaagca gacctagcta ccgctgaagc
      421 tactatcgca gagcttgagc aaaaaattcc tgagttagag aaaaaaattc aagaagctca
      481 ggaaaaacta aactatgaaa atcgaccatc acctaaacgt gtgggcagtg atgatgaaga
      541 tgacacagta gctagaaagc ttatgtcaga aaaggaagct cttaaggctg agcttcaaaa
      601 gactaaagaa gcgctagata cagctaaaag agcttatgct ggcatcgaag aaagaaaaca
      661 agtagcagca actaagctag atgcagctaa caaggctttt gctggagttg aagaaaagca
      721 tgctcaagca atggctgcat ttggagcagc attcgcagca tacaaggaag ctgttaaggc
      781 tgaattgaag gcagcaggtg ctagcgactt ctacaccaag aagattgact ctgccgacac
      841 agttgacggt gttaagacac tcagagaaat gatcttagac tcaattgcta agccagaggt
      901 tgaaccagag gctaagcctg aacctaagcc agaaccaaaa cctgagccaa aacctgagcc
      961 aaaaccagaa cctaagccag aaccaaaacc tgagcctaag ccagagccaa aaccagaacc
     1021 taagcctgag cctaagccag aaccaaaacc agaacctaag ccaaaacctc aacctaaacc
     1081 agctccagct ccaaaacctg aagctaagaa ggaagagaag aaagcagcgc ctaagcaaga
     1141 caccaacaaa ttgccatcaa caggtgaagc tacaaatcca ttcttcaccg cggcagctct
     1201 tgcagttatg gcaggtgcag gcgtggctgc agtgtcaaca agacgcaaag aaaactaagc
     1261 cttatacccc agtggtaaag cttgagcgag aacaatttgt tctcgctttt ttagtgtctt
     1321 aaaagcacct acagcaatca taggtgctta acaagatatg tctaacgatt gctatcagct
     1381 gtagagaata aaaaggagag actaagcctt gctcacaagc tacttagacc gaaggagctt
     1441 taggatttct atgatttgct gaggggagtc cttacagccg cagctgatcc acttaatgat
     1501 gatgacctca atagaggcaa tgtatagctc aaaaacatat ttttgggtaa cttcaggata
     1561 atcttgtgat tctgcacaat tcatgaggtt ggaataggaa ataatatccc taatataatg
     1621 attaaaaatt ttataaatat taggataata aaggattaag ctttgcatga cctcctgatt
     1681 gtcagagagg tagtttagga tttttaaggt aatagttgta tcaagtgatg gggattggta
     1741 aatgatagag gtgatatcat ctaggtaaac gccgatcatt tccctatcta agtccttctt
     1801 agagttgaaa taatgttaaa aggttgttcg actgatatta gaagccttgc taatatctga
     1861 tacagtaata ctgtccttat ccttgtattg tagtagtcgg cagtagcttt taattatttt
     1921 tttacaagtt tgtttatttt tatccattgt atcattaact ccttaaaatt gaacattaat
     1981 gttaattttg tacataatat tttttgctaa cattatacaa tgatgaacgt gatttgtaaa
     2041 attaaatttt gcaaatcaat aatgtaaaag gaggattttg tttgaaacaa ctgacaaaga
     2101 tcgttagtgt ggtcttgttg ctggtcttta cccttagtgc tagcctgcac aaggttcggg
     2161 caactaatct tagtgacaac atcacatcat tgacggttgc ttcttcatca ctccgagatg
     2221 gagagagaac gacggtaaag gttgcgtttg atgacaaaaa acagaaaatc aaggcagggg
     2281 atacgataga ggtcacctgg cctacaagtg gtaatgtcta cattcagggc tttaataaaa
     2341 ccataccgct taatattaga ggggtagatg ttggtacctt ggaggtcacg ctagacaagg
     2401 ctgttttcac attcaatcaa aatattgaaa caatgcatga tgtctctggt tggggagagt
     2461 ttgatattac tgttagaaat gtgacacaaa ccaccgctga aacatcagga acgaccacag
     2521 taaaggtagg caatcgcact gctactatca ctgttactaa gcctgaggca ggcactggta
     2581 ccagctcatt ttattataag actggtgata tgcagcccaa tgatactgag cgtgtgagat
     2641 ggttcctgct gattaacaac aacaaggaat gggtggccaa tactgttaca gtcgaagacg
     2701 atattcaagg tggtcaaacc ttggatatga gcagctttga catcaccgta tctggttatc
     2761 gtaacgagcg cttcgttggg gaaaacgctc tgacagagtt tcatacaaca tttccaaatt
     2821 ctgtcattac ggcaacagat aatcacatta gtgtgcggtt agatcaatat gatgcctcac
     2881 aaaacactgt caacattgct tataagacaa agataacgga ctttgaccaa aaagaatttg
     2941 ccaacaacag taaaatctgg taccagattt tatacaagga tcaggtatcg ggtcaagagt
     3001 caaaccacca agtagccaat atcaatgcta acggcggggt tgatggcagt cgctatacca
     3061 gctttactgt caagaaaatt tggaatgaca aggaaaatca agacggtaag cgtccaaaga
     3121 ctattactgt tcagctttac gccaatgatc agaaagttaa tgataagacc attgaattga
     3181 gtgatactaa tagctggcaa gcaagttttg gtaagctgga taagtatgac agtcagaacc
     3241 aaaaaattac ctacagtgtc aaggaagtga tggttcctgt tggctaccaa tcgcaggttg
     3301 agggggatag tggagtagga tttaccatta ccaacaccta tacaccagag gtcattagca
     3361 ttaccggtca aaaaacttgg gacgacaggg aaaaccaaga cggtaaacgt cctaaggaga
     3421 ttacggttcg tttattggca aatgacgctg caactgacaa ggtagcaact gcttcagagc
     3481 aaaccggctg gaagtataca tttaccaatc taccgaaata caaagatggt aaacagatca
     3541 cctacacgat ccaagaggac cctgtggcag attacaccac aaccattcag ggatttgata
     3601 ttaccaatca tcatgaggta gccttgacca gcctaaaggt catcaaggtt tggaatgata
     3661 aggacgatta ttaccataaa cgtcccaagg agattaccat tttgctaaag gcagatggca
     3721 aggtgattcg tgaacatcag atgacaccgg atcagcaagg aaaatgggaa tacacctttg
     3781 accagctgcc ggtctatcag gcaggcaaga aaatcagcta cagcattgag gaaaaacagg
     3841 ttgctggcta tcaagcccct gtctatgagg ttgatgaagg cttgaagcag gtcactgtaa
     3901 ccaacaccct taacccaagc tacaagctgc ctgacaccgg aggacaagga gtgaaatggt
     3961 acctgttaat cggtggcggt tttatcatcg tcgcaatcct tgtactgatc agcctttatc
     4021 aaaaacacaa gcgccataac atgtcaaaac cataacatgt aatagaggag agagagctat
     4081 gaaaacaatc aaattaatct tgacgagctt gcttgtcacc ttcctaacaa tgctgtcagg
     4141 aaaggcattt gctgatacag caagctatac catcactgtt gagggagcta cagcaggtca
     4201 cacctatgag gcttatcaga ttttcaaggg tgacttgttt gacagtaccc tatcaaacat
     4261 cacatgggga ggtggtgtta caccttttga atttgatggt tcaaaagacg ctgctaagat
     4321 tgcagaggga ttgaaggaag caaatgcagc tgcctttgcc aaggaagcag gtaagcactt
     4381 gacagcaacc attgcaggaa caggaacaca tgcaatcacc gttaacgagg ctggctacta
     4441 cctcatcaag gacaaaaatg attctcaaac aggcaagcat gacgcctaca cctcatttgt
     4501 cctgaaggtt gttaaaaata ccagcttcaa accaaaatct gctatcccaa cagtccttaa
     4561 aaaggtcaag gaccgtaatg acaagacagg tcttgagaca ggctggcaag attcagctga
     4621 ctatgacaaa aatgacaagg tgccattcca gctaaccgca accctaccgt caaattacga
     4681 tgcctttcaa gaatactacc ttgaatttgt agatacctta tcaaaagggc taagctacaa
     4741 caaagacgcc aaggtctatg tggttaatgg agatactcgt caagatatta ctaattcatt
     4801 tacagttagt gaagatggtt catcttttaa aatcaataac ctaaaggctg ttcagggagt
     4861 aacaataaca gctaccagta agatcgttgt cgaatacact gctaccctca atgaccaagc
     4921 ggccatcggc aaaaaaggaa atccaaacga agttgctttg aaatactcaa acgatccaaa
     4981 cgctcttgga aaaggagagg agtctccaaa aggggagaca ccaaaagaca aggttatcgt
     5041 tttcacctat aaaactatca tcaataaggt tgatcaagat caaaaagccc taaaaggtgc
     5101 aggctttacc ctttataagc tggtcaaagg tgataatggc gaggaaaaat atcaaatagt
     5161 ccaagaaatt aaagcagggg atacaactag ctttgagttt gttggacttg acgctggtga
     5221 ttacaagctc agcgaaacaa caacacctgg cggttacaac actattgcag atgtcatgtt
     5281 cagcattgta gcgcagcatg aaaccgagtc agacgatcct cagttgacta gcctaaccgt
     5341 tgacaaagca actggcttca ctgctgatac agaagctggt accgtatccg caactattgt
     5401 taataaaaaa gggtctatcc tcccttcgac aggaagtatc ggaacaacca tgctctatgt
     5461 gtttggagta atgctaatga caatatcaac gctgtttatc tttcgtcaga aacagcaata
     5521 agatcgtgtg agtaggtaaa aagaagtgga tagacgtctt accaagacct attcacctct
     5581 ttttttgata gaggctatag aatgaagaaa agtgtcattt tttggagtgt gattttggtg
     5641 gcaggctgtc tgattgtcct ttaccccacc cttagtaact attggaatgc acagcaccaa
     5701 tcacagctca tcgctgacta tgtctcaagc acgcaagctt tgagacataa ggatagtcag
     5761 ctcatgctag aagcagccaa tcagtacaat cagcagctaa aagctaacca tgatcctgat
     5821 ttaaccttga ccgatagtga ggcagaagcc tatcagcagc agctggatct gacaaataca
     5881 ggtatcatgg cctacataga tattccaaag gtgcatgagc ggctgccgat ttatcatggc
     5941 accgatgagg agatcctaca ggtggctatc ggtcatcttg caggcacctc tttgcctgta
     6001 ggtggcaagg gaacacatgc tgtcatctca ggacatcgag ggttaccctc tgccaagcta
     6061 tttaccaata ttgataagct gaggattaac gataccttta ccatcaccag tcttaatagg
     6121 actatgacct atcaggtgga taagattgct accgttttgc ctgatgatgt cagcctctta
     6181 aggatagagg aggggaagga tctggtaacc ttggtcacct gtacccccta cggtgtcaac
     6241 acgcatcggc tcttggtcag agggcatcgt atcaaaacag cgacaccaac cgctgcaaga
     6301 ggatctcaaa agcctagtag gctaatcctc tggctcttgc taatcagtgc attagggcta
     6361 tctctcgtac taataggcac ttggcgctgg cgtaggaggt ctaaagcatg agcaggcttt
     6421 ccagaagcaa ctaagtcaaa tcatcaaccc ttgataggtt actgaggacc tatcagggga
     6481 ttttttagtg ctaaattgcg actatgatta aaaacacaga aatcgttttt ttttcttagt
     6541 gaccgaaaac gctttaaaag agcgagcatt tggagccttc aaaagtgaca tctgagcata
     6601 acatgataaa attgacttat aaaacctaat aaaatgataa aaggaggaga gttaacgaca
     6661 aaatattaga tatttattta atttgttgtt tttgaaaacg ttttataata agaaaggata
     6721 gcatgatgaa aaaacaatca ttcacacact cacgtaaacc taaattcggt atgagaaaat
     6781 tatctattgg ccttgcctca tgtatgctag gaatgatgtt cctaacaaca ggacatgttt
     6841 ctggtgaggt agttgaagtt tggcctaatg ggcaaaatcc taatggtaaa atagaaattc
     6901 taagtcaaac tgagcactct gagcatttac agaaattacg cgatattgaa gatttccaag
     6961 ctcaaaagca agctgatcat gttcgttaca ctaaatggtt agatggggta actgttgatg
     7021 agcatgaatt cagaaaaatc aaggaatatg acacagaata ttatgtaaca cctcttttaa
     7081 gtggtaaagg ttactatgat atcaataaag atttcaatca agatagtgat aaatgtgctg
     7141 ccgctgtagc ggctaatatg ttccattatt ggtttgatag aaatagagac agtattaatc
     7201 gtttcttaag tcaaagtcca ggtgaaaatg gtgttattaa acttgaaaat gaaaaaacaa
     7261 tagaagtatc aaaattttta gaaacttacc gtagtgatgg tgattatctt gataaaagtc
     7321 cgttttttga ccttatcagt aacagcttta aaggtcctgt ttgggcaaat aagctattgg
     7381 atgcttacat taacggctat ggttatatcc ataa
//
LOCUS       DARYVE010000081         7221 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYVE010000081 DARYVE010000000
VERSION     DARYVE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7221
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..606
                     /locus_tag="TVW25_001788"
     CDS             <1..606
                     /locus_tag="TVW25_001788"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379393.1"
                     /translation="NMISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNN
                     TDDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEET
                     LFRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGL
                     GKMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
     gene            complement(1022..1402)
                     /locus_tag="TVW25_001789"
     CDS             complement(1022..1402)
                     /locus_tag="TVW25_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1379394.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(1436..2428)
                     /locus_tag="TVW25_001790"
     CDS             complement(1436..2428)
                     /locus_tag="TVW25_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1379395.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(2444..2989)
                     /gene="srlA"
                     /locus_tag="TVW25_001791"
     CDS             complement(2444..2989)
                     /gene="srlA"
                     /locus_tag="TVW25_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1379396.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(3125..3586)
                     /locus_tag="TVW25_001792"
     CDS             complement(3125..3586)
                     /locus_tag="TVW25_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1379397.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(3586..5358)
                     /locus_tag="TVW25_001793"
     CDS             complement(3586..5358)
                     /locus_tag="TVW25_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1379398.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(5652..7001)
                     /locus_tag="TVW25_001794"
     CDS             complement(5652..7001)
                     /locus_tag="TVW25_001794"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1379399.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         2134 a         1644 c         1443 g         2000 t
ORIGIN      
        1 aatatgattt ctgtaaagaa aaatttatgt cgcttaggtg ttttgtctag tagtttatta
       61 cttttaacag ctgcaacgac tccatctgtc attgcttttg cggatattca aacaagtgcc
      121 ataaaaaata atacagatga cgcagatggt atgtattttg ttcaaagtta tgaaatgtct
      181 gtagaagata aagaattgct tgttcgaaat gttaaagcaa atcatcctac agtttctgaa
      241 gattttatca gagaagttat tgaaagacaa ttagtaggtg attatacatt acctgaagaa
      301 gagactcttt tccgctcagc atggcaaggg gttacagtag atcaattggg agcagctcta
      361 gatgtggcta ttggtatggc attaacaggt ggagctggat caattgctgc tggtgttttg
      421 agagtcggaa aaagagaagc tgttggtcgg gtaaaatcaa ttctaattaa atatgggcta
      481 ggtaaaatga tagctgaaat tccagtcgat tacatgttaa atttattatc gccaggatat
      541 catatagcta gatatattga tagtattgat acagttccta ataataatag aattaacctt
      601 tggtaagtta ggaaatttag tactgtgaaa aaaatttata ttttatattt tgtgctttat
      661 tgcttattat accttgtcat atcattatta attagctatg gtatgtccca ttttcttaac
      721 atggaattta aatggtggaa taaattagct atatctctaa catctttata tattatttat
      781 caaatgctga aaaaggataa attaattaaa taatcaacta atgtacaagt tgtctttaag
      841 ctgaaaagag gctatcaaca gcctcttttt ttgatgatat agataagccc aatgcttcct
      901 tagaagagct cttctgtgag atgaccttat cacctgacat tagctgcttg gctcatgcct
      961 acagctaaag gaaatgccct gcaaggatag cagcacttag cctgctggtc tacggcgtgt
     1021 ctcagctgca cctaagccaa gcaaagattt gtactaggct gccctgcctg acctgtggca
     1081 gccctttgcc cttgacatgc agagtaccgg gaagagagct ggctgtggag ccatcaaaag
     1141 aaatggttat atgccctagc tgagcaagat ttttttcaac aacagcacct actgctgtga
     1201 tgtcatatgc catttgatca atgactagct gaccaccagc agagatagac ccagacactt
     1261 gcttgttgtc aatcgtatag caaaagtctg ccaagtctgc cggtgctccc tgatcaaaaa
     1321 gaataagcat attggcagca ctaatcatgt ctgccgcctc cgatccaata gcggtaactc
     1381 ttgtttcaaa tacttttatc atacattctc tctcttccta tcatacgata gctccttact
     1441 gatacaaacc aatacttgca atccaagcaa caacaacccg aggaacacca tttaaaaagc
     1501 gtgaataaag cacagatggc accccaacct ctactgtctc agcattagcc tctgataaac
     1561 caagcgctac tggaatgaaa tcacagccat tttgcgtatt aatagcaaaa agtgcaggaa
     1621 gagccatttg tggtggaata gtgccttttc caatctcaac accaatgagc gttccgatga
     1681 tttgactaat aaccgcacca ggtcctaaca gcggtgataa aaatggcaac gaacagataa
     1741 agccaatgat aatcaagccc caaatattac cagccagcgg taccatgagc ttggctagcc
     1801 aattaccaac accagagcct tggataaaac caattaaaag agagacaaat gccatgaatg
     1861 gcaaaatcgt attgattaag gtctggatag cctcacgcgc cgcttggttg aagatagcaa
     1921 ctaccttacc tgctcccata ccaatgcggg caacaaagct gctttctgcg cgctgctcag
     1981 taatcttttt gctagtatca tagctgctag cctttggaac tgatgactcc ttagcactag
     2041 caacatgagc ctgagcgtca ctggctgtga tttgctcaag acctacagca gacacgtaaa
     2101 tgtcctcggt aatgtactgt gccaagggac cgcttttacc tgtcgccacg atattaatgg
     2161 ttggaatgcc ttttttaggg taaataccgc agcgtagggt gccgccacaa tccacaatag
     2221 ctagggctat ctcatcatca gggattgagg tcacaaagcc attgaccgcc tccatacctg
     2281 ttagggcagc aattttatcg acaatgtcag gcttttttcc accgccagta atatagataa
     2341 atttgtgctt agcttctgtt ggtgtaatgg ttagcggccc accatagcca ccgctcccct
     2401 taacaactgt aatactgtga taagtcatca tgctacctct cttctataat tcaatcatct
     2461 tacttaatgt cacaccctgc tgcttggcca cgtaggctgt cgtaaagtca gttacccagc
     2521 caccaacaaa gttcatgatt aacccaacca agaggtaacg aatcgccaag tccatttggc
     2581 tcaagcctag cgtcttgata cctgaggcaa tacctaacca gacaaacaat tctcccggat
     2641 taatgtgtgg aaagacaccg tttgacgtat gacaaaattg catttgagcg gcaacatagc
     2701 ttggcttgta atactcgggc ataaagcgtc ccatgctgat tgccatcgga ttacccagca
     2761 taaaagctga aataaaaggc aataccatgt agcgactgat agggttttta gcagagattt
     2821 ttgccaattg attgaccctt tgatctccta aaataccaat taaggcattc attgcaacca
     2881 gcagcatcaa gaccaccggc acaatgccag tcatccagct gacaaaggtt tcaccaccaa
     2941 gctggaagag cttcataaag ccttccgcaa atcttgttat catttccata aataaactcc
     3001 tcatatgatg tacttacaag caagacaata caaatgtact gcctgcttga taatagctgc
     3061 ttgagctgga ctcaaaacag cttttatgtt gacaaggcaa gcaatcaatc ctgcttttgg
     3121 caccttactt gaagcgtgcc agcagctgct tggcctgtag ggtccaatca aaggctgagg
     3181 catattttgg tgcgtcctca tagacccctg cctcaaccct caagaagacc tctcttgcgt
     3241 cctcaatagc caagcgcagc aatttatttt ctcgtctaat caagggattg tagcgatcaa
     3301 aataatgaat atcctgaccg atataagctg gcattggctt aaacctggct gccactgtca
     3361 caccctgcat ttgcctagca tctaatacct tacctgactg atccaaggca aacatgacaa
     3421 tggttccggc cctgattttc ccggctctac ggccaatagc aacgcgcccc tgtcgtctaa
     3481 gactggcata aacagcattg aagtgcttaa gctgtctcag acctagcaat aattgaaaaa
     3541 ggtaagcaac tatgacaaat agtccaaaaa taaccataaa actcattaaa aaactccttt
     3601 ttccttggta aatgcaataa actcagcttg actttttagg ctccttagct ccgcctgaag
     3661 cttatcatcg cttgctattt tgaaaatatc atcataaatt ttcaagagat cagcctccat
     3721 ctgcgcttca accctcttgg aaatagccac tagaaaaata aactccacca gacagtcatg
     3781 ctcacgataa ggctcgtcta atagacccag cagcaggaca gtctttgttt ccttgtcatt
     3841 aatcgtatgt ggaaaggcaa tgcgattgcc aaataaggtt gattgcaggg cctcacgctc
     3901 tagcaggcgt tgaccaaact gcctgtcaac cagctgcttt tcctcaagca gctccgccat
     3961 ttcagtcagg tagtcagtgt aggccttccc ctttgacaga cgagcaaagt gtagggtgat
     4021 ggtcgccagg tttttctggt gataatgatg taccctgcgc cattcatttt gcagccactg
     4081 gtcatcaaac agatttgtga tttggagaac aggagatttt agctgaccaa acttcagcgg
     4141 cacagtggtg aatatggcaa aatagtgatc attgtcatca ggattgaatt gctcctcaga
     4201 gaattgtgag atcaacaaat caggacctag caccttgctc aagcgacgac aaatcatatt
     4261 ggcagtgcca cgacctgtcg tgcagacaac ggcaattttt ttcactgttg gctctgtcac
     4321 atgctcagcg tctttcatca tcatttcgaa ataaagggcc aaatagctac actcagacaa
     4381 ttctatggcg cagtcaaact cctctgctaa gacctgagct gcgacaatgg ccatatcaaa
     4441 ggccaagggg tatttgtatc taatttctcc atgaaaaata tcattggcct gaacatgaaa
     4501 aatcaaacga ttcaccaaga gcttcaaatg cgtatgcaaa gcaacaaaaa gcttgtcttg
     4561 gtcaatagtc accaagagac tggtcttgat gtgctcaatc atttttgaat aaagcctgac
     4621 aatgctctgt tgcagaggct tttcttgata ggctagatcc tcgatgtatt ggatattcaa
     4681 gggaaagcta ataaactggc gctcgtattg actcagtgac agctgatagg ctagctcaat
     4741 gtgatagacc agctcctcca taaaggcact ggaatcaacc tcattgctat agtaaggaat
     4801 aggatctgtc agatacctgc cctgacgcat tcgctcaatg gttatcgcaa agctcttggt
     4861 caaaagctct tggattttgc gaggaagctg gtaggtctga tacagctcat ctagaaaaaa
     4921 caagctatca ccacacaagc cctgcggctc aaagtatttg taaacctcat gaacataaag
     4981 cagccgaagg ttcaactcag tgccaacagc ctgtatgcca tgattgggct tgccctgaat
     5041 catgaccgaa taggtcctag caagagcctt ggctgccttt aggtctttat tgatcgtgct
     5101 gcgactgacg ccaatctcat cagccaaatc atcaatgact aaagctgagg agctttgcag
     5161 tagccttttt agaagataag ctacccgctt gctagcggaa ttaaagtcac tagccttacg
     5221 taaactacca gctaatatcg tctctaatct agcataatca tagacctgca gctgcaaaaa
     5281 ggcgccttgt tgggtgatgg tcgcatctcc atctaaaatg tcattgagct gaccaatgct
     5341 acttgcagcg tttgacatcg tcttttcaca aagtcacagc ttagaaagct agcagaggag
     5401 acaaaagcaa gaccttatca gctaacagca gcatattaaa cgaacagcta gtgatactga
     5461 tcctactaag catagagctc caaaagcctg gcttaaatag tattcaaaat agaacaagag
     5521 ctctcaagaa caataaccta gcgcactact tgccttgata agcctaaccg accttgaaaa
     5581 gaagcaaaaa aaagagcctc tcacgagact ctttgttatg ttttagcaga ctagtctagc
     5641 tagctctgtc attacaagcg tgcgttgagc gctgctccta gctcttcaaa gcctggctta
     5701 ccaagaaggg caaacatgtt tttcttgtaa gcctcaacac ctggctgatc aaatggattt
     5761 accccattga ggtagcctga aagggcaata gcaagctcaa agaagtagat cgtatagcct
     5821 agtgtaaatt cgtcttgctc tggaagcgtg ataaacatat ttggcacacc accgtctgta
     5881 tgggcaagaa ggacaccatc tgttgctttt ttgttgacaa agtcaacgtc tttgccttgt
     5941 aggtagccaa ggccatcaag atcctcagcc atttctggga taatcacatt ttgacgtggc
     6001 ttatccacac gaatcactgt ctcaaagagg ttacggtagc cttcttggat aaattgacca
     6061 agagaatgca ggtctgtcga gaaattagct gaagttgggt aaataccctt ttggtccttt
     6121 ccttcagact caccagccag ttgcttccac cattcgctaa aatactgcaa tgatggctca
     6181 tagtttgcca aaatttcagt tacatagcct ttgcgataga ggatattgcg aactacagca
     6241 tattggtaag cgatgttttc tgagatttta tctgatgaca ggtccttacg agctgcattt
     6301 gccccctcca tcagcgcggt aatatcagca cccgatgctg caattggcaa caagcccaca
     6361 gctgtcagca ctgaaaaacg accaccaaca ttatctggca caacaaaggt ttcccaatga
     6421 tttgcatcag cctcaacctt aacagcaccc ttgaccttat cagtcgttgc atagatacgc
     6481 ttgttggcct cttcttgacc gtacttttta acaagtaatt ctttaaagac acgaaaggcg
     6541 attgcaggct ctgttgttgt accagactta gaaatcacgt taacagagaa atctttatct
     6601 tgaacatagt ccacaagatc agcaagatag cttgatgaga tggagttccc agcataaaga
     6661 atttgtggtg ctttgcgctc ttttgctgtt tgtaggttgg caaaatggct gttcaaaaag
     6721 tcaatcgcag ccttagcacc aaggtaagag ccaccaatac caatcacaac aagaacgtca
     6781 ctgtcagcct taatcttctc agctgcttta aggatacgag caaattcttc tttgtcatag
     6841 ttttcaggta actcaagcca gcccaagaaa tctgatccag gtccagtgcc ctgacgtagt
     6901 gcctgatcag cctctgttac ctgaccttgt aaaaagtcaa tttcatgctg tccggcaaat
     6961 tgctcaagaa cctttgaata atcaaatgta atatgtgaca ttattttact cccttaactt
     7021 ttaaagtttc attagtatca taaccttttc tattcaatat ttcaatgttt tttatttttg
     7081 gggagggtgg cctgacttta acgacatgag gatcatttct gtctaaaagc agctttgtga
     7141 tgagcctagc gcttccctat ctgcttctac tatagcttac tggggctgat ccgggtgatg
     7201 tggtagcctc ttggcatagc c
//
LOCUS       DARYVE010000082         7218 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYVE010000082 DARYVE010000000
VERSION     DARYVE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7218
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..7152
                     /locus_tag="TVW25_001795"
     CDS             <1..7152
                     /locus_tag="TVW25_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1379400.1"
                     /translation="AKVLEIRDKKEVLSTLIFKDVKEVGEYQFHPQSEEFILNELSIS
                     EEKLKAPEHITDKIDKKEGYEAELVLDMKNKELRQHLRYNGYMLSSNVAVSYDSYKAI
                     LKNLSYLLDDNHRNIMLTGYVNEQIEKDKAKEERKEPVYQEGMNVRYQGKEYIISEIQ
                     DYKTYKTIKLDDSEGYLNGFITGSEIIPFRNERELDLEIISTTEKLQEQSINGEDLIL
                     LDIEEYNKKGLSVIFQNKEYEITGNNFNPVGMSRLQLVSNTEKLMTEISYTPQRPVAN
                     LYAKKDLLERFNLNEKNSEKSIEAKQMSLTDIFEEQDTTKGKEEISSEKERVPVNIGA
                     KVIYQGEEYTVSAFEYNNILEKNDIWLNPVSKNNHQIPIVSFSDREELNEKLIVIDTN
                     LNLGEDKSELLHHSLDVINDKGSVIANQFIVKVDNQNRELTVYSEQNPNSHREFELSF
                     DYLNGLGQIDGDGNNLKLTKHKKETIDKKLKSYHSWKEDGEKRGIPGIAGSSITSPIT
                     DEMFWQMKEYEEKLKEEERYAPDDKYLGGIPPINYKITKEDEILPPSERLKNNIEAIK
                     VLKEIEERHSHATKEEQDILSRYVGWGGLSDVFDEEKGGQWKDAREFLKENLSPSEYD
                     AARESTLTAFYTPKIVIDSIYQAVLNMGFESGNILEPSMGTGRFIGNLPDSMKGSKFY
                     GVELDSISGRIASRLYPNAKIQIKGFEETTFSNNLFDVAVGNVPFGEYKIVDREYEKN
                     NFLIHDFFFAKTLDKVRSGGVVAFISSSGTMDKKSEDIRRYISERAEFLGAIRLPNNT
                     FKGEAGTEVTSDIIFLKKRDRLVKLDEEWVKLGTDERGLTYNKYFVDNPDMVLGNMEE
                     ISSRFGTSLACVADENSTLKEQLDTAIKNIKGSYEKIELNNEFEVETIPADDSVKNYS
                     YAVIDDKVYFRENSVMQKLNLNKNDEEKVRAYLGIEKALRQVIAYQKEDYSDTEIKEK
                     QGELNRIYDEFSKKYGILNSKANKKLFREDANYSLLSTLEKLDKEGNFIEKSDIFTKR
                     TIKKAVAIEHTDNLTEALILSISQKGKVNFEYMEKLTEKTRGEIIEGLKGEIFLNLDG
                     FDPSDTTPFSSAIDLGDFSRSYVTADEYLSGNIRDKIEVIDSYIKNVEHEFEQNEQLE
                     NIDADVLKQGSETLKKELSSLNYQRQKLLEVMPKELEASEITVRMGATWIPEKDYKSF
                     MFHLLKTSASNRWNIDIKYTNFTGEYRVEGKSIDKGNDLANFTYGTSRVSAYKLIEDT
                     LNLRDTNVYDQVIDENGKKSSVLNQKETMLARSKQEIIKEEFKNWIFDDIDRRTRLVK
                     EYNEKFNSIRLREYDGSNLTFDGMNPEIELRPHQRDAIARGLFGGNTLLAHEVGAGKT
                     FEMIGIAMESKRLGMSNKSMFVVPNHIVEQFGREFNELYPAANILCATEKDFTPDKRK
                     RFCSRIATGDYDAVIIGHSQFEKIPISKQRQEYELQSQIDEIIDFIEEYKRNRDQKFT
                     VKQLEKTKKGLEAKLKKLNDDYRKDDVVTFEELGIDKLFVDEVHAFKNLYVFTKMRNV
                     AGITTTDSQKSSDMLMKCRYMDEITGNKGIVFATGTPVSNSMAELYTMQRYLQYDELK
                     KMHLQHFDSWASTFGETVTAIELNPEGNGYRSKTRFAKFYNLPELMNMVKQFMDIKTA
                     DVLNLPVPNAHYETIKTKPTEEQKQILETFSERADKVRGKQVDSSVDNMLLITNDGKK
                     MALDQRLINPLLPDDPNSKVNTCVNNIFSIWDKYRDEKSTQLVFCDMSTPSSEFNIYD
                     DIKEKLTKMGIPKNETEFIHNAKNNKEKDKIFDKVRKGEIRVLLGSTQKMGAGTNAQN
                     KLIATHDLDVPWRPADLEQRKGRIVRQGNENDDVHIFRYITENTFDAYLFQTLETKQT
                     YISQIMNSKTPVRVAEDIDEATLNYAEIKALATGNPLIREKMDLDVEVSKLKMLESNF
                     KSNLYKMEDKVVKVYPKEIKSLKEKIENLKKDIEKVEPYREEKLEKYDQTTLENMGEN
                     EKQVGIKADKEAISKFTSLTLNGKKYTDKKQAGEFLINKIKGIKKLDDFRSEEVKIGE
                     YRNFDLFAYYDRFSNQYKFNLKGEENHYGEFGTDEIGNITRMDNVLDRMPERLEQTLG
                     KLKDTENQLETAKLEIKKKFPQAELLKEKTLRLAEVNNLLDMGQKGDLKEEKNPLLEE
                     VKEELIHFLNKEYDEAHSIEDFDTMFPDLTDIGLAYTTTPDEKHEIQTSLDLINYKMN
                     TYVDNTLIDSFQYTYDPLNASDTKELIQIKTNIGFWDFNELVYVDEEKLKASLGLEID
                     DDGNFYDPLSKDMDLDGVMDRYDADFRDSKVQSFGDLDKKEKASVMDRLGYFKEKIKK
                     GGLQNENIDRKIECKEEVR"
BASE COUNT         2891 a          917 c         1499 g         1911 t
ORIGIN      
        1 gcaaaggtgc ttgaaattag agataagaaa gaagtcttat caactcttat ttttaaagat
       61 gtaaaggagg tcggcgaata tcagtttcat ccacaaagcg aagaatttat cttaaatgaa
      121 ttgagtatat ctgaagaaaa attaaaagca ccggaacata taacagataa gattgataag
      181 aaagaaggct atgaggctga acttgttttg gatatgaaaa acaaggagtt aaggcagcat
      241 ttaagatata acggatatat gttaagtagc aatgtggcgg tttcctatga tagttataaa
      301 gcaatactta aaaatctttc ttatctgctt gatgataatc atagaaatat tatgcttacc
      361 ggctatgtca acgaacagat tgaaaaggat aaagcaaagg aagaaagaaa agaacctgta
      421 tatcaagagg gaatgaatgt aaggtatcaa ggcaaagaat atatcatttc agaaattcaa
      481 gactataaaa catataaaac aataaagcta gatgattcag aaggatattt aaacggcttt
      541 ataacgggca gtgaaattat tccttttaga aatgaaagag aacttgattt ggaaatcata
      601 tctacaacag agaagttaca agaacaaagt ataaatggtg aagatcttat tctgttagat
      661 attgaagaat ataacaaaaa aggactttcc gttatctttc aaaataaaga gtatgaaatt
      721 acaggaaata attttaatcc tgtaggaatg agcaggttac aacttgtctc gaatacagaa
      781 aaactgatga cagaaatttc atatacacct caaagaccgg tcgcaaatct ttatgcaaaa
      841 aaagatctcc ttgaaaggtt taatttaaat gagaaaaata gtgaaaaaag tattgaagca
      901 aagcaaatgt ctttaacaga tatatttgag gaacaggata caacaaaggg aaaagaagaa
      961 atttcaagtg agaaagaacg tgtacctgtc aatatagggg caaaggtaat ctatcaggga
     1021 gaagaatata cagtaagtgc ctttgagtat aataatattt tagagaaaaa tgatatatgg
     1081 ctaaatcctg tatcaaaaaa taatcatcaa attccgattg taagtttttc tgacagagaa
     1141 gagctaaatg aaaagctcat tgttatagat accaatctta acttaggaga agacaagtcg
     1201 gaactgttac atcatagttt agatgtaata aatgataaag gttctgtgat tgccaatcag
     1261 tttattgtaa aagtcgataa tcaaaacagg gaacttacag tatatagtga acaaaatcct
     1321 aatagtcata gagaatttga actttctttt gattatctaa acgggcttgg gcaaattgac
     1381 ggagatggaa ataatctaaa acttacaaag cataaaaaag aaaccattga taaaaaattg
     1441 aaaagttatc attcttggaa agaagatggg gaaaaaagag gaattccggg aatagcaggt
     1501 tcttctatta cttcacctat tactgatgaa atgttttggc agatgaaaga atatgaagaa
     1561 aaattaaaag aggaggaaag atacgcccct gatgataagt atttgggagg tattcctcca
     1621 atcaattaca aaatcacaaa agaagatgaa atcttgccgc cgtccgaaag gcttaaaaat
     1681 aacatagaag ccatcaaggt attaaaagaa attgaggaaa gacatagtca tgcaacaaag
     1741 gaagaacagg atattttgag tagatatgtc ggctggggtg gactttctga tgtctttgat
     1801 gaagaaaagg gaggacaatg gaaagatgca agagaattct taaaagaaaa tctatcaccg
     1861 tctgagtacg atgcagcaag ggaaagtacc cttacagcct tttatacacc gaagattgta
     1921 atagacagta tctatcaagc cgtattaaat atgggatttg aaagtgggaa tatcttggaa
     1981 ccaagtatgg gaactggcag atttataggc aatcttccag acagcatgaa aggcagtaaa
     2041 ttttatggtg tagaacttga cagtataagt ggtaggatag caagtaggct atatcctaat
     2101 gctaaaatac agatcaaagg ttttgaagaa acgacttttt caaataatct gtttgatgta
     2161 gcggtgggaa atgtaccgtt tggagaatat aagatagttg atcgtgagta tgagaaaaac
     2221 aattttctta ttcacgattt tttctttgcc aaaaccttgg ataaagtacg ttccggtgga
     2281 gtagtagcct ttataagttc aagtggaact atggataaaa agagtgaaga tatcagaaga
     2341 tatatttcag aaagagcaga gtttttagga gcaattagac tacctaataa tacttttaaa
     2401 ggcgaggcgg gtacggaagt aacaagtgat attatttttc ttaaaaagag agatcgactg
     2461 gtaaaacttg atgaagaatg ggtaaaactt ggcactgacg aaagaggact gacatataac
     2521 aaatactttg tagataaccc tgatatggta cttggaaata tggaagaaat atcaagcaga
     2581 tttggaacaa gtcttgcctg tgttgcagat gaaaatagta ctctgaaaga acagctggat
     2641 accgccatta aaaacattaa aggaagttat gagaagatag aattaaataa tgaatttgaa
     2701 gtggaaacca ttccggctga tgacagtgtg aaaaattatt cttatgcagt aattgatgat
     2761 aaggtatatt ttagagaaaa ttccgttatg caaaaattga atttaaataa aaatgatgag
     2821 gaaaaagtaa gggcatatct tggaatagaa aaagcattaa gacaggtaat tgcttatcaa
     2881 aaagaagatt attccgatac ggaaattaag gagaagcaag gggagttaaa tcgtatttat
     2941 gatgagtttt ccaagaaata cggaatttta aacagtaagg cgaataaaaa actgtttcgt
     3001 gaagacgcta attattcttt actgtccact ttggaaaagc tggataaaga aggaaacttt
     3061 atagaaaaat ccgatatctt tacaaaaaga acaataaaaa aagcagtagc catagagcat
     3121 accgacaatc tgacagaagc acttatccta tctatttctc aaaaagggaa agtcaatttc
     3181 gagtatatgg aaaagctcac tgaaaaaaca agaggagaaa tcattgaagg attaaaggga
     3241 gaaatattct taaatttaga tggatttgat ccaagtgata cgactccttt ttcttcagcc
     3301 atagacttgg gagatttttc aagatcttac gtaactgctg atgaatattt atctggaaat
     3361 atcagagata aaatagaagt aatagattcg tatataaaga atgtagaaca tgaatttgaa
     3421 caaaatgaac agcttgaaaa tattgatgca gatgtactga aacagggtag tgagacttta
     3481 aaaaaagaac tgtccagttt aaattaccaa agacaaaagc tgctagaagt aatgccaaag
     3541 gagcttgagg caagtgaaat aaccgttaga atgggagcaa cttggatacc tgagaaagat
     3601 tataagagct ttatgttcca tcttctaaaa acatcggcat ctaatagatg gaatattgat
     3661 attaaatata ccaattttac aggggagtac agagttgaag gtaaaagtat agataaagga
     3721 aacgaccttg ccaatttcac atacggaaca agcagagtaa gtgcatataa actgattgaa
     3781 gatacattaa accttagaga taccaatgta tatgatcaag tcattgatga aaacggaaag
     3841 aaaagttctg tactaaatca aaaagaaacg atgcttgcaa gaagtaaaca ggaaattatc
     3901 aaagaagagt ttaaaaattg gattttcgat gatatagaca gaagaacaag gcttgtaaaa
     3961 gaatacaatg agaaattcaa ttcgataagg cttagagaat atgatggaag taatttaact
     4021 tttgacggaa tgaatcctga aatagagctt agacctcatc aaagagatgc gattgctaga
     4081 ggacttttcg gtggaaacac cctacttgca catgaagttg gagctggaaa gacttttgag
     4141 atgataggaa ttgctatgga gtctaaaagg cttggaatga gtaacaagtc aatgtttgta
     4201 gttccaaacc atattgtaga acagtttggt agagagttta atgaactgta tccggcagca
     4261 aatattcttt gtgcaacaga aaaagacttt acaccagata aaagaaaaag attttgctca
     4321 aggattgcaa ccggtgatta tgatgcggta attatagggc attcgcagtt tgaaaagatt
     4381 ccaatttcaa agcagcgaca ggagtatgaa cttcaaagtc agattgatga aattatagat
     4441 tttatcgaag aatataaaag gaatagagat cagaaattca ccgttaagca gcttgaaaaa
     4501 acgaaaaaag gactggaggc aaaactaaag aaattaaatg atgattatag aaaagatgat
     4561 gtcgtaacct ttgaagaatt ggggatagac aagctatttg tagacgaagt tcatgctttt
     4621 aaaaatttgt acgtttttac aaaaatgcgt aatgtagcag gaattacaac cacagattct
     4681 caaaaatcaa gtgatatgct gatgaagtgc agatatatgg atgaaattac cggtaataag
     4741 ggtattgtat ttgcgacagg aacccctgtg agcaattcta tggcagagct ttataccatg
     4801 cagcgttatc tccaatatga cgaacttaaa aaaatgcact tgcaacactt tgattcttgg
     4861 gcatctactt ttggagaaac tgttacagca attgaactta atcctgaagg gaacggatat
     4921 cgaagcaaga caagatttgc aaaattttat aaccttccgg aactgatgaa tatggtcaag
     4981 cagtttatgg atataaagac tgctgatgta ttaaatcttc ccgttccaaa tgctcattat
     5041 gaaacgataa aaaccaaacc gacagaagaa caaaaacaaa tccttgaaac tttttctgag
     5101 agagctgata aggttagagg aaaacaggtg gattcctctg tcgataatat gcttctgatt
     5161 actaatgacg gaaagaaaat ggcacttgac caaaggttaa ttaatccatt acttcctgat
     5221 gatccgaaca gtaaagtaaa tacctgtgta aataatatat tcagtatttg ggataaatat
     5281 agggatgaga agtccacaca attagttttt tgtgatatgt caacaccatc aagtgaattt
     5341 aatatttatg atgatataaa ggagaagctg acaaaaatgg ggattcctaa aaatgaaaca
     5401 gagtttattc ataacgcaaa gaacaacaaa gaaaaagata agattttcga taaggtacga
     5461 aagggtgaaa ttcgtgtgct tctcggttca acgcagaaaa tgggagcagg gacaaatgct
     5521 caaaataaat tgattgctac ccatgatctc gatgtaccct ggaggcctgc ggatttggag
     5581 cagagaaaag gaagaattgt aaggcaaggt aatgaaaatg atgatgttca tatctttcgt
     5641 tatattacgg aaaatacctt tgatgcgtat cttttccaaa cacttgaaac caagcaaact
     5701 tatatatctc aaataatgaa ttcaaagaca cctgtaagag tagcggagga tattgatgaa
     5761 gctacattaa attatgcgga gattaaagca cttgcaacag gaaatccgct tattcgtgaa
     5821 aaaatggacc ttgatgttga ggtaagtaaa cttaaaatgc tggagtccaa ttttaaatcc
     5881 aacctatata aaatggaaga taaggttgta aaagtatatc caaaagaaat taaaagtcta
     5941 aaagaaaaaa tagaaaattt gaaaaaggat atagaaaaag tggaaccgta tagggaggaa
     6001 aaactagaaa aatatgatca gactacttta gaaaatatgg gtgaaaatga aaaacaagtg
     6061 gggataaaag cagataaaga agcaatatca aaattcacat ctttaacttt aaatgggaaa
     6121 aaatataccg ataaaaagca agccggagag ttcttaataa acaagataaa aggaataaaa
     6181 aaattagatg attttcgttc tgaggaagta aaaatcggag aatatagaaa tttcgatttg
     6241 ttcgcatatt atgacaggtt ctccaatcag tataaattca atctgaaggg agaagaaaat
     6301 cattatgggg agtttggaac ggatgaaatc ggaaatatca cccgaatgga taatgtactt
     6361 gataggatgc ctgagagatt ggagcagaca cttggaaaac ttaaagatac cgagaatcaa
     6421 cttgaaacgg cgaagcttga aataaaaaag aaatttccac aggcagagct tttaaaagaa
     6481 aagacgttaa gacttgctga ggtaaataat ttgcttgata tgggacaaaa aggagattta
     6541 aaagaggaga aaaatccact tttggaagaa gtgaaggaag aactgattca ttttctaaat
     6601 aaagaatatg atgaagcaca cagtatagaa gatttcgata caatgtttcc tgacttgaca
     6661 gatataggtt tggcatatac gactacaccg gatgaaaagc atgagataca gacaagtctt
     6721 gatttaatca attacaagat gaacacttat gtagacaata ctttaattga cagttttcag
     6781 tatacttacg atccacttaa tgcaagtgat acgaaggaac ttatacaaat caaaacgaac
     6841 ataggttttt gggattttaa tgagctggta tatgtggatg aagaaaagtt aaaagcatca
     6901 cttggacttg aaattgatga cgatggtaat ttctatgatc cgctttcaaa ggatatggat
     6961 ttagatggag taatggacag gtatgatgca gactttagag atagtaaagt acaaagtttt
     7021 ggagatttgg ataaaaaaga aaaagcatcc gtaatggata ggcttggata cttcaaagaa
     7081 aagataaaga aaggaggcct acaaaatgaa aatattgata gaaagataga gtgtaaggag
     7141 gaggttagat agttggaata tcacaaaaat attagagcaa cggatagaga aatgcagaaa
     7201 ctttttgaaa atgaggag
//
LOCUS       DARYVE010000083         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYVE010000083 DARYVE010000000
VERSION     DARYVE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(25..486)
                     /locus_tag="TVW25_001796"
     CDS             complement(25..486)
                     /locus_tag="TVW25_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1379401.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TVW25_001797"
     CDS             complement(530..1606)
                     /locus_tag="TVW25_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1379402.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TVW25_001798"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TVW25_001798"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1379403.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TVW25_001799"
     CDS             4915..5859
                     /locus_tag="TVW25_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1379404.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            complement(5884..6021)
                     /locus_tag="TVW25_001800"
     CDS             complement(5884..6021)
                     /locus_tag="TVW25_001800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379405.1"
                     /translation="MAADMLRLIIRSSSSSYRYLLGRLFALAVVVPALADELSTGRAQ
                     E"
     gene            6118..6768
                     /locus_tag="TVW25_001801"
     CDS             6118..6768
                     /locus_tag="TVW25_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1379406.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1998 a         1792 c         1334 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attaccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYVE010000084         6781 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYVE010000084 DARYVE010000000
VERSION     DARYVE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6781
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            82..155
                     /locus_tag="TVW25_001802"
     tRNA            82..155
                     /locus_tag="TVW25_001802"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:116..118,aa:Met,seq:cat)
     gene            180..252
                     /locus_tag="TVW25_001803"
     tRNA            180..252
                     /locus_tag="TVW25_001803"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:213..215,aa:Phe,seq:gaa)
     gene            258..328
                     /locus_tag="TVW25_001804"
     tRNA            258..328
                     /locus_tag="TVW25_001804"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:290..292,aa:Gly,seq:tcc)
     gene            358..431
                     /locus_tag="TVW25_001805"
     tRNA            358..431
                     /locus_tag="TVW25_001805"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Ile,seq:gat)
     gene            441..528
                     /locus_tag="TVW25_001806"
     tRNA            441..528
                     /locus_tag="TVW25_001806"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:475..477,aa:Ser,seq:gct)
     gene            587..1402
                     /locus_tag="TVW25_001807"
     CDS             587..1402
                     /locus_tag="TVW25_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1379407.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            1405..1908
                     /gene="mreD"
                     /locus_tag="TVW25_001808"
     CDS             1405..1908
                     /gene="mreD"
                     /locus_tag="TVW25_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1379408.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            2004..3182
                     /locus_tag="TVW25_001809"
     CDS             2004..3182
                     /locus_tag="TVW25_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1379409.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            3287..4249
                     /locus_tag="TVW25_001810"
     CDS             3287..4249
                     /locus_tag="TVW25_001810"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1379410.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            4609..5379
                     /gene="recO"
                     /locus_tag="TVW25_001811"
     CDS             4609..5379
                     /gene="recO"
                     /locus_tag="TVW25_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1379411.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5495..6502
                     /gene="plsX"
                     /locus_tag="TVW25_001812"
     CDS             5495..6502
                     /gene="plsX"
                     /locus_tag="TVW25_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1379412.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6495..6743
                     /locus_tag="TVW25_001813"
     CDS             6495..6743
                     /locus_tag="TVW25_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1379413.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
BASE COUNT         1897 a         1085 c         1583 g         2216 t
ORIGIN      
        1 ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaacag cgtgcgtggg ttcgaatccc
       61 acatcctcct ttaaagatta tcgcgggatg gagcagttag gtagctcgtc gggctcataa
      121 cccgaaggtc gtaggttcaa atcctgctcc cgcaattata taaaagatat atgctggttg
      181 gctcggtagc tcagttggta gagcaatgga ttgaagctcc atgtgtcggc ggttcgattc
      241 cgtctcgcgc cattttagcg ggtgtagttt agtggtaaaa ctacagcctt ccaagctgtt
      301 gtcgcgagtt cgattctcgt cacccgcttt atagttttcc caagctatag tgtgcttggg
      361 cgcgtagctc aggtggttag agcgcacgcc tgataagcgt gaggtcggtg gttcgagtcc
      421 actcgtgccc atcattattt ggagaattac tcaagaggct gaagaggacg gtttgctaaa
      481 tcgttaggtc gggtaactgg cgcaagggtt cgaatccctt attctccgta ttgtaaaggt
      541 gattatcata ctgataatcg tttttttatt tttagaggtg attttattga aaaagcttaa
      601 cctatctcgt ctcttttttt ggttaacatc attagcttta ctggctttga ccttggttct
      661 tctttttaga gtagctattt ctccatattt atcaatgatt atccgaaatc ccgttacaaa
      721 aattgatgct ataatgtcta agccttttgc tgttataaag gagggtgcaa aggaattaga
      781 tagcttgatg tctgcttttt ctgaaaataa gcatttaaaa aaggaactta ggtcctataa
      841 attggatcag ttacaggttg acaagctaaa atctgaaaat cgagagctca aggaactgtt
      901 agggttggat tatggtactg ataatcaatt tgctgccaga atgatatcaa gaaatcctta
      961 tagctggaat aaatcgctgg tcattgatag cggcaaaagg gaaattaagg agaagtcttt
     1021 ggttacttca gagcttggac ttattggtcg tgttacagct gttagccagt catctgctca
     1081 tgttgaattg ttaacatctg ggaagaatat tgagttgccg attaaaattg tagataagga
     1141 taaggtgatt tatggcaatt taaaggcatt taaatcagaa agtaaaacaa tggttgccag
     1201 cgaatttaat tctaatgact caatatcatt agatgctaag gtttatacaa gtggattaga
     1261 tggtgagact gtggcagata ttcctgttgg aaaggttacg ggctttaaaa atgctgctga
     1321 taagctaaag cgtcgtattt ttataaaatt gtatgctgat actgataatc ttgactatgt
     1381 tcttgttgtt ggaaaagagt gaatatgaaa aaatcttcag agctattagt ccttttgcct
     1441 tttcttttat tttttgttga tgcacacgtg tcagacctga tcagctcaat gttacctgag
     1501 ggttactcgg tagtatcaca cctcttttta ctgtttttcc tgatccttat ggtagcgttt
     1561 agatctaagg gagttatttg tttcttctct cttcttttag gattattgtt tgattattat
     1621 tattttgatc atatagggat tttgtctctt gccttgcctt ttggaacaat gatcgttcta
     1681 gggctattaa ggttcttttc tggttccatt agtcagctac aatttttcct tttctttact
     1741 ctttatatgt ttcttgtaga tgtatcaagc tttattttgg caaacagcta tcagttaact
     1801 gatatgactt ttccttatgt aatgacgttt cagcttgctc cgactttaat cgtcaatctc
     1861 cttattttgt tttgctttag aaaattaata ttaagtcaat tttattgatt attacataca
     1921 actgtaacag atgcgtaaca ttaaacgctt gattttttga tagaatataa tgtgtcttat
     1981 cgaaaaggag taattttttt agtatgaaaa aaagaattct atcagcggtt cttgtaagcg
     2041 gtgtgaccct tggaacagca actacagtgg gagcggatga tttagattcc aaaatagcgt
     2101 tgcaaaattc agttatttct aatttaaata aagaacaaaa agctgcgcag gatagaatga
     2161 agactttgca aagtcaggtt agctcattac aatctgaaca agaaaggtta gtcgctaaaa
     2221 atggtgagct tgaagcgcga tctgctcagt ttgagcagga gattcaagtg cttgccagtc
     2281 aaattattgc tcgtaatgaa aagttaaaag gacaggctcg tagtgctcaa aagggaaata
     2341 cgttaggtta cctcaatgca cttttgaatt ctaagtcaat ttctgacgtt attactcgtt
     2401 tggttgctat taatagagct gtgtcagcca atgcacagat gttggaaaag caaaaggctg
     2461 ataagctttc tcttgaagaa aagcaacagg aaaatcaaga agcgattaat acaattgctt
     2521 caaatattac agcaattgaa tcaaaccaag tagctttaaa gactcaacaa gcagatttag
     2581 aggttgccaa ggtagatttg gcgcttcaat tagcaactgc tgaggacgag aaggctagct
     2641 tgattacccg taaagaggct gcagagcagg cagcagctca agccaaggct caggcagagc
     2701 aggaagcagc agccagagca gcacaggctc aagctcaagc acagtctgta gcggcagctc
     2761 aagcagcagt gactcaagcc gtaccaacac cagctccagc gcaggcacag cctgttgtgg
     2821 cgccagcagc tatggtttca acaccagcgg tgtcgtatgc ctatgatcct tctaatccgt
     2881 accctgtcgg ccaatgtact tggggagtta aggctttagc tccttgggtt ggcaattatt
     2941 ggggaaatgg tggtcaatgg gcatcaagtg cagcggcagc aggtttccgt gtaggtgcaa
     3001 caccaatggt tggctctgtt gttgtatgga atgatggtgg ctatggtcac gttgcctacg
     3061 taacaggtgt tcagggtgga cagattcaag ttatggaagc caactatgct ggaaatcaat
     3121 ctattggcaa ttatcgtggt tggtttagcc caggtgctgt atcgtatatt tatccaaatt
     3181 agaaaataag taaaggtaag aatcaggatt cttacctttt tatttccatt gaaaaattga
     3241 ttgaaaaggg ttaaaatggt ataggatcaa aactttggag gaaaaaatgt cttattctga
     3301 tttaaagctg tttgcattat cgtcaaacaa ggaattagca gaaaaagttg ctgctgcgat
     3361 gggaattcaa cttgggaagt ctacggttcg ccagttttca gatggtgaga ttcaggtcaa
     3421 tattgaggaa tcaatacgtg gacaccatgt ttttattttg cagtcaacaa gctcgcctgt
     3481 taatgataac ctaatggaaa ttttaattat ggttgatgct ttaaagcgtg ccagtgctga
     3541 gaaaatttct gtggtaatgc cttattatgg ctatgctcgt caggatcgta aggctcgttc
     3601 gcgtgagcct attacctcta aattagtcgc taatatgcta gaggtggcag gtgttgatcg
     3661 tttattgact gttgatttac atgctgcgca gattcaaggc ttctttgata ttcctgttga
     3721 tcatctcatg ggagcacctt taattgctga ttattttgat cgtcatggtc tagtaggtga
     3781 tgacgttgtt gttgttagcc cagatcatgg tggtgtgacg cgtgctcgta agctggcaca
     3841 attcctccaa acgccaattg ctattattga taagcgtcgt agtgttgata aaatgaatac
     3901 cagtgaggtg atgaatatca ttggtagtgt tgaaggtaaa aaatgtattc tgattgatga
     3961 tatgattgat actgctggta ccatctgtca tgccgctgat gcgcttgctg aagcaggagc
     4021 aacagcagtt tacgcatcat gtactcaccc agtgctgtca ggaccagctc ttgataatat
     4081 tcaaaaatca gcgattgaaa aattgattgt tttggatacg atctatttac cagaagaaag
     4141 actgattgat aagattgaac aaatctctat tgcagatttg attgcggaag ctatcattcg
     4201 tatccatgaa aaacgtccat tgtcacccct atttgaatta gggaaatgat aaggttagcc
     4261 tgaggtagta agccttaggc ttttttatgt tttaaaaggc tatttgatta ccaaagcagt
     4321 gtttgattta acgccataga taggcttcac tgtcttatgg taggtgttga gctattatag
     4381 caaaaagtca tgtgtaggtg ctgtgtttaa acagctagcc tatgattcat atagttatgg
     4441 ctagtgactg ttgagcttct tattctcaga gttgttacga gccttaagta cagtgttagt
     4501 catgcaattt tcctggattt tgggtataat atagctgtat ttaaggtgtt ttaaaggtct
     4561 agtaagaaag gcattattac tagctgagaa gcttggttat ggagatatat gcgtattcag
     4621 aggtcacttg gtattgtctt gtacaataaa aactatcgtg aagatgataa gctcgtaaaa
     4681 atatttacag aagcggcggg caagcgtatg tttttcgtga aacatattgg tcgttctaaa
     4741 ctagctcctg tggtccagcc tttaacggct gctgattttc tattgaaaat caatgattcg
     4801 agcctttctt atatagagga ttataatcag gtggaggctt atcggcacat caatgaagat
     4861 ttttttaggc tatcctatgc tagttatgtc ttggctctgg ctgatgcggc tattccagat
     4921 aatgagcctg atcctcagtt gtttgctttt ttgaaaaaga ctcttgatct gatggaagaa
     4981 gggctagatt atgacatttt aacgaatatc tttgaagtcc agattttgga tcgttttggg
     5041 gtgagaatga attttcatga ttgtgttttt tgtcacagaa ccaatctgcc ttttgatttt
     5101 tctcataagt attcaggtgt cctttgtccg cagcattacc atgaggatga gaggcgatat
     5161 ggcttggatc ccaatgtgat ttatttgctt aatcgttttc aaacgcttaa tattgatgag
     5221 ctaaagacta tttctgtgaa tactggtatg aaaaaaaagc ttcgtctttt tattgatgcc
     5281 ttgtatgagg attatgtcgg tattcgtcta aaaagtaagg tttttattga tgatttggct
     5341 aagtggggag atattatgaa aaacaagcag ggcttgtgag ctattcaggt gtggatttgt
     5401 ccttttatgg gaattgtctg gggaatatgc tataatagtt acgttattct ctaggatatt
     5461 tttcgttaag aaaaatagga ttaaaggagc aaaaatgaag aaaattgcaa tagacgctat
     5521 gggtggtgat tatgccccta aagctattgt tgagggtgtt aatcaggcga tagaatcctt
     5581 ttcagatatt gaaattcagc tttatggcga tcaatcaagg attgagtctt acctagttaa
     5641 atcagatcgt gtgtccattg ttcatacaga tgaaaaaatt aattctgatg atgagccagc
     5701 aaaggctatt cgtcgtaaga agaatgcttc tatggtttta gctgcaaggg cagttaagga
     5761 tggtcgggct gatgcagttc tttcggcagg taatacaggc gccttgttag ctgctggttt
     5821 gtttattatt ggtcgtatca agggagtgga tcgtcctggt ttgctgtcaa ctctgccaac
     5881 ggttgatggt tcaggctttg acatgttaga tttgggtgcc aatgctgaaa acacagcaga
     5941 gcatttacac caatatgcta ttttaggctc tttttatgca aaacatgtgc gtggtattgc
     6001 caagcctcgg attggcttgc ttaataatgg tactgaggca actaagggtg attctcttcg
     6061 caaggaggtc tataattttt tagcttcaga cagcagccta cagtttattg ggaatgttga
     6121 ggcaagagat ttgatgtctg gcgtggcaga tgttgtggta gcagatggct ttacaggaaa
     6181 tgctgttttg aagtcgattg aaggcactgc tatgagtatt atgggacaat tgaaatcagc
     6241 tatagcagta ggtggtgtta aggcaaagtt tggagctctt ttattgaaga gtagccttta
     6301 tgacttaaag gatactttag attattccag tgcgggtggg gctgtattgt ttggtcttaa
     6361 agcacctctt gtgaaatcac atggttctag tgatgccaag gctatttttc ataccattaa
     6421 gcaggttcgt acgatgctag aaacagatgt agttggccaa ttagttgagg agttttctaa
     6481 ggagagtgat gtaaatgact gaggaagtta ttttagagaa aatcatcgca ttaatcaaga
     6541 agcaaagaag tcgtatagac tttgacatta cagaaaaaac agcactaaag gatgatttag
     6601 gagtagattc gattgaactg gtagagtttg ttattaatat cgaagatgaa tttggtattg
     6661 atattcctga tgaagatgtt gatggcatgg tatctatggg agatatgcta aattatttgg
     6721 tcaagcgttt aaaccaaagc taaatagttt taaaagagca ccagctcttt ttttgtttcc
     6781 g
//
LOCUS       DARYVE010000085         6687 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYVE010000085 DARYVE010000000
VERSION     DARYVE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6687
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(87..3197)
                     /locus_tag="TVW25_001814"
     CDS             complement(87..3197)
                     /locus_tag="TVW25_001814"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1379414.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            3439..3810
                     /locus_tag="TVW25_001815"
     CDS             3439..3810
                     /locus_tag="TVW25_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1379415.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3810..4508
                     /locus_tag="TVW25_001816"
     CDS             3810..4508
                     /locus_tag="TVW25_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379416.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            4518..5312
                     /locus_tag="TVW25_001817"
     CDS             4518..5312
                     /locus_tag="TVW25_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379417.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(5359..5970)
                     /locus_tag="TVW25_001818"
     CDS             complement(5359..5970)
                     /locus_tag="TVW25_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1379418.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            6061..6409
                     /gene="ssrA"
                     /locus_tag="TVW25_001819"
     tmRNA           6061..6409
                     /gene="ssrA"
                     /locus_tag="TVW25_001819"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         2073 a         1449 c         1186 g         1979 t
ORIGIN      
        1 ggttgagtaa ggtgtggact aaaacaagtg ataaagtcgg gattatagca cattcgtttg
       61 caaattactt cactaattcg ctatttttat cgaaaaaccg ttttcaacac gtaggggcta
      121 atagcctcct ccaaatcctt actaacatca accctaatat ggtttaactc taaggtttct
      181 ttgccttctt gataatggat aataacagga gtctcccctg aaaaggctgt taatatgtca
      241 gaaatagcag catcatgctg atggttttca accaatagcc aatacctttg actctgagct
      301 aatcgaagct ggtgacagac tagctgcaag cggttatctc tttcttttac cctgccattg
      361 atatagtaaa tatgcccctc ttttaggtct tgcttataga cagcatattg ctcaggaaaa
      421 agggtaacat ctaatttctg tttggtatca gtaacactca aaaaggccat ctgctgtccg
      481 cttgattttg tccgaataac cctgatcgca tctatttgaa ccagcaaagt agcttctgta
      541 tccttcacta actttgtgat tggtgtgact gctactgtgc ttttttcagc gacagctagc
      601 aaggggtgct tgctcatgcc aacaccaagc aaatcctgct caaagtaata tttctcagca
      661 gctgaataat cctcagtctc tacccagcta aaggaggaat ccgcaaaaag tgatcccaat
      721 tcattgacaa aggttagcag tccttctaag ttgttaatga ttttttggcg atttttttca
      781 aacccatcaa acaggcctat tttgataagg ggctctaaga agctggtttt ctggtatttt
      841 tcaggaatgc tgcacaaaaa gctttcaaca ctggtaaagg gcctattttc aatgatccaa
      901 tacgaaaatt ctctaggaag acccttgatg ttttttaagc ccatataaat cttatgacgc
      961 tcaatcttat cattgaaggg aatggtgttt atcgtcacct gcgcggcctc aaagccaaaa
     1021 tctaacgcat ctgtgatgta atcactgcta gaataattca tcatgacatc aaaaaatacc
     1081 tcaggatagt gcgctttaaa ataggctagc tgaaaggcta gggcagcata agcaaaggca
     1141 tggctgcggt taaagccgta gcctgcaaat ttttccatac gtgcaaacaa tagtctggct
     1201 gtctcctcag agcgacccaa ggctctagca ccagtcagaa aatcctcctg cattctttgc
     1261 atctcaacga ggtttttctt agacatagca cgccgtagca aatcggcctt tccaagtgta
     1321 aagcctgcat aaacttgagc aatctgcata acctgctcct gataaagcat gataccatag
     1381 gttggctcta atatcggagc aatcaccgga tctattagat caatgttttc ctgtccctgc
     1441 cggcgcttaa taaaattctg cgtgtaatca cttgctcccg gtctatttaa gctggttgtc
     1501 gcaacaattt cctcaaagct agtcggcttg atccgtttta acaggctaat cgcaccatgc
     1561 tgttcaaatt gaaaaatgcc cttggtatca cccctagcaa acaaggctat cgtttcagga
     1621 tcctctaggt taatagcttc aatgtcaatt gaaagaccgt aatcgttgac caccttttcc
     1681 tgcattttct gtacaagcgt caaatttctc agaccaagaa aatccatttt cagcaagcca
     1741 ttagcttcaa cagcactggc atcatactga gtcaccatca tatcctcccc cttttttaag
     1801 ggaatatggt tggtcagatg gtcatcactc atcacgatac cagcagcgtg aatagaggtc
     1861 tgtcttggat tgccttcaat gcgcttagct atctcaaatg ccttttgaaa ctctaagcgg
     1921 ctattaatgg tctgtctgaa ggctatattt ttctcataaa cagtgctcag ggtatccttg
     1981 aacccaattt ttttagttag gcttgttagc tcgtattctg ggacaccaaa gcgtttgaac
     2041 acatcacgaa cagcctgctt aggaccaaaa gtcgaaaagg taacaatctg agctgagtgc
     2101 tcactaccat accggtctcg aacataatga agaaactctg agcggtaaat atcaggcaaa
     2161 tcaatatcaa tatcaggcat gctgtagcgt tctttattca aaaagcgttc aaacaataaa
     2221 ttgtttttga caggatcaat cccagtaatg cgcaacgaat aagccactag actgcctgct
     2281 gctgaaccac gccccatgcc catataatag cctctactcc ttccaaagcg cagcaaatcc
     2341 cagacaatga gaaaataatc atcaaacccc atatctgaaa taatagccag ctcctctgcc
     2401 agacgaaatt ggtaaggctc cttccataat tgcttttctc ttagaccaga ctcggtcaat
     2461 tctcttagct cttcttttgc tggcttatcg cggttaaatc tcggaagctt taaatcagta
     2521 tcaaaatgat aagcaatcga agctgttaga tttacgagat tcaccaaagc ctcagggcac
     2581 ttttcctgga aaatagccgt catctcctga caaggcgcta aaaactgatc cttggctact
     2641 agagccgtat ctgctaagct aatattatca cgaatggcat gcagcatttg cagagtctca
     2701 gtctcagcat tatcaaaata acgtaccgtt ctaagcggaa tcagtctttc tgtagagtct
     2761 atctttgaca agtcgcttgc ctcatcaatg ccaatgaagt aatcaaaagg aagccctaaa
     2821 tcacgcaagc tctgactaaa aggaacgata actgctatcc cttctaaata ctgcaccaat
     2881 gtgtctaggt ctaggtctcc agacattttt tcagtcgaaa gctttaagag ctgctgatag
     2941 cctgtatcat ttttcgcaac aagcttcagc gtaagagcct gctctttaac tgtaatagcc
     3001 acctcaagac ctaaaatcgg ctgaagccca tgcctttgac agcccttaat aaaatgatat
     3061 gccccatata gattatcctg atccataatc cctatggctt gatagcctaa tcgtttggct
     3121 tgtttaaaat aatggtctaa atcaatcaaa ctatccataa aggaataaac tgtttttgta
     3181 tctaactgag caaacatgga catctccttt agcgttctta ctaccattat actatgaaaa
     3241 agactttact gcccagattt taagctttta atagcagtga tctgtcttta ctgcaccact
     3301 atcagcagga atcccactag cattgcaagc cagtatgtaa ctagagatga cacacaaggc
     3361 ttgacaagtc aatcgttttt ttgtatcatt taattagtac aaatattaat cgcagatttt
     3421 agaaagaaag gagacagtat gtcttggaaa tttgatgaga aatctcctat ttacgcacag
     3481 atagcacagc atatcatgct gcaaattgtc agccaagaga tcaaaagtgg agatcagctg
     3541 ccgactgtcc gagaatatgc tgaaattgcc ggcgttaatc ccaacaccat gcaaagagca
     3601 cttaccgaat tagatcgtga aggcatagtt tactcgcaac gaactgccgg ccggtttgta
     3661 acagataacc aagagcttat cgcgcgcaaa agacgagagc tggccatcaa cgagctcaag
     3721 tcctttatta gcaatatgat caaaataggt tttgaacgtt cagaaatcat tcctgtttta
     3781 agtacctttt tagaggaggg atcaaactaa tggcacaact attacagctg caccacgtct
     3841 caaaatctta caaaaaacaa ttagctattg atgatttaac cataacaatc ccttctggaa
     3901 aaattatcgg cttactagga ccaaatggta gcggcaaaac tacactaatt aagctaatca
     3961 acggactttt acagccagac aagggagaca ttgttattga cggctttaga ccatctgtag
     4021 aaactaaaaa aatcatttct tacttaccag atacgaccta tcttaatgaa agtatgaaaa
     4081 tcaaggatat gctagacttt tttggtgatt tctatgccga ttttgacaga gataaagcga
     4141 ccagtctcct gaaggattta gacttagatg ctgaagagcg ctttaaaaac ctatcaaagg
     4201 gaaataagga aaaggcacag cttatcctcg tgatgagccg caaagcaaag ctctatatcc
     4261 ttgatgagcc tatcggaggg gttgacccgg cagcaagaga ttatattctt aaaaccatta
     4321 ttaataatta ctctgagcaa gcctctgtta tcatttctac tcacctcatc tcagacattg
     4381 agcctgtact tgatgaagct attttcttaa aaaatggtaa gctctgcctt tctggaaacg
     4441 ctgatgattt acgagttcag catcagcaat cgattgattc attatttaga gagatctaca
     4501 aggtttagga ggtaggcatg tttggaaaat tattaaaata cgaatttaga tcaattggca
     4561 agtggtattt tgcgcttaat gccggtgtca ttgctatcgc gatagtcctt tcttttacca
     4621 tcaatacgct tacaaacaat cctgacgagg ttggtttaac aacaagtctg gcaaacaaaa
     4681 tggttcctct cacactctca ttaacgtttg gttctctgat tgccggatca ttcttatcaa
     4741 cgctattaat catcattaat cgctttaaca aaaatgtctt tgggcgcgag ggatacttaa
     4801 cactgacact accagtaaca gcacatcaga ttatcttgtc caagctgtta gcgtcctttg
     4861 tttgcagtat ttttaatggc attaacctat taatcggtat ctttatttta atagcgccaa
     4921 cagttgactt tacctatcta ctaaaggtgc taaagacaat tatgaagcca gaaaacttag
     4981 tcgaaaatgc ttctatcctc atctacatgc ttttgtcaac cataacaagt atactattga
     5041 tttatctagc aatctcaatt ggtcagctat tttcaaatcg tcgtggtttg atggcatttt
     5101 gtgcctattt cattttagtt attatcatta ttgtcgtcat gacttattta aatgatgcgt
     5161 ttttcaccgt caacccaaat agctcagact cgctactcta tttcggtgat catacagcca
     5221 tatctatttt aaacatagag caactagttg aaggcattat cctttacgtt gctactcact
     5281 tcatcatcaa aaacaagctt aatatccaat gataacaaaa agtctagcca ctgcttatca
     5341 ggcaatgcct agactttttt aatggaaaaa ccataggatc aaatcctttc caaagataaa
     5401 aagatagctg tagccaataa ttgatagtgg cttcgtgatt aaaataatgg tcacaaaacg
     5461 cttcaacgac atctctgtca gcccagtaat catgaccata atatctgctg gtgaaatcgg
     5521 agaaagcata cagagaataa acaatctctc ataatatggc atctctaatt ttctctcata
     5581 cttgtaaaag gtctgttcct ctataaacag taaaataaag cgcctaccat aggtcttcac
     5641 aagtaaaaac agaatcacac taccaatgaa gataccaaca tagttataaa gaaaacccag
     5701 caaagggcca aaaatcaaaa agcctgcaat agttgtcata ccacctggaa taataggaaa
     5761 aacaatctga acaatttgca caccgacaaa aacaaggggg ccaaaaacct tgtgactatg
     5821 aacaagatcc ttgagtgcat tgctgtcatt taaaatgcca agcctgtaaa accaaaaggc
     5881 tagcaaaaaa gatccgacta aagccagact tcctaatagc ttaatcactt tttgccatat
     5941 cacataaggc ttcaactcat tatttctcat agcttcatca taccataagc gctatttttt
     6001 tgccatttta aaaaaatttt gctatactag catccgtaag tatctcatac gcctttttat
     6061 ggggttgtta cggattcgac aggcattatg aggcctattt tgcaactcat cggcagatgt
     6121 aaaaatgcca gttaaatata actgcaaaaa ataacacaac ttacgcttta gctgcctaaa
     6181 aaccagccgg cgtgacttct ataggattgc ttgtgtctta ttagaggtct caaaacagca
     6241 agctacgttt aggtgattgt ctagtcacct aaaaagagaa ccctagactc gcaggctgat
     6301 ggcttgagtt atgtgtcctt ggtctgttaa agtaagacat aacctatggt tgtagacaaa
     6361 taggttagca ggtgtttgga cgtgggttcg actcccacca gctccatcaa tacttaccgt
     6421 aagttaccat aacttactaa aaccttgtta aatcaaggtt ttttcttttt gtcctgttcg
     6481 tgggttaccg taagtttcta tgaaagtgat agcaaaaaaa aggccaaaaa atcctttaag
     6541 aacagcttga attttctctt tagctaatct tatatttatt tttttataat acttcttcta
     6601 cttgcttcat tgacagcaca ttatcaaatt ttttcggata attgccctgt attgcctgtt
     6661 atatagacat catttactgc tgcttta
//
LOCUS       DARYVE010000086         6302 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYVE010000086 DARYVE010000000
VERSION     DARYVE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6302
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            88..237
                     /locus_tag="TVW25_001820"
     CDS             88..237
                     /locus_tag="TVW25_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379419.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(234..434)
                     /locus_tag="TVW25_001821"
     CDS             complement(234..434)
                     /locus_tag="TVW25_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1379420.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            545..829
                     /locus_tag="TVW25_001822"
     CDS             545..829
                     /locus_tag="TVW25_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1379421.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            826..972
                     /locus_tag="TVW25_001823"
     CDS             826..972
                     /locus_tag="TVW25_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379422.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            1176..1421
                     /locus_tag="TVW25_001824"
     CDS             1176..1421
                     /locus_tag="TVW25_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1379423.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
     gene            1583..1966
                     /locus_tag="TVW25_001825"
     CDS             1583..1966
                     /locus_tag="TVW25_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1379424.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            1947..2180
                     /locus_tag="TVW25_001826"
     CDS             1947..2180
                     /locus_tag="TVW25_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379425.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            2177..2317
                     /locus_tag="TVW25_001827"
     CDS             2177..2317
                     /locus_tag="TVW25_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379426.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            2326..2532
                     /locus_tag="TVW25_001828"
     CDS             2326..2532
                     /locus_tag="TVW25_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379427.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            2667..3395
                     /locus_tag="TVW25_001829"
                     /pseudo
     CDS             2667..3395
                     /locus_tag="TVW25_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            3572..4783
                     /locus_tag="TVW25_001830"
     CDS             3572..4783
                     /locus_tag="TVW25_001830"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL1379428.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            4776..5612
                     /locus_tag="TVW25_001831"
     CDS             4776..5612
                     /locus_tag="TVW25_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1379429.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            5797..6138
                     /locus_tag="TVW25_001832"
     CDS             5797..6138
                     /locus_tag="TVW25_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379430.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
BASE COUNT         2302 a         1040 c         1370 g         1590 t
ORIGIN      
        1 ggccagcagt attttattaa taaattcctt aatcaggaat atctgccagt ttagaaagga
       61 aacaaaacca acgaaaagga gaaaagtatg ccagaggatt taatcaaaca actagaagct
      121 ggttcagaat ttctagcaaa gacatgttta catagcaaga ttattatcac ggtggatggt
      181 gttcggcttg tggaaacaaa agagttccac ccagtgagcg gaactctact agattagaca
      241 atacgtgtat aagtgtgtat cttagctaat ctatgaatat ttgagccaac agacccaaca
      301 agaacagaac ggtattccgt ttggcttaca ttgtgataat ggtaaataga accattatta
      361 aactcaactt ccaaagtgtt attttcccaa ccaacacttc ggacgttact agatgaaacg
      421 tattgacgtt gcataacttt ttctcctttc cgcgatgata gctttattat agcacgcaag
      481 gagaatacaa aaaaagtccg acgggaatcg gactcgacaa taatatttat gaggtaattt
      541 tatcatggat agtagattat tacaaatgct tgatgagttt gaggcgggtc tgatagaccg
      601 taaaatcaaa gtcataggca tgcttaataa cgaaacggaa atttatccgc tagagcttaa
      661 caaaaagcaa atcagtaaga tgctgggagt tgatcctaaa acatttgacg taagatttaa
      721 tagccacaaa gattttccgc gcatcgaaac gggaggtcgg gaaaaatacc cacgagattt
      781 agttattgag tggtatagca aaaactggga aaggacgggg ataagatgat taaaaaacta
      841 tttaacttta tttttgcaaa gccaaaagaa gaatcaaggc aaccttatca acaaccgaga
      901 ggttttctgg attttgaaac aggtaaacga attgaaatag atccgataac aagaaaggaa
      961 tacttcgtat gatgcatcaa attaatatat cgcttagaaa ttttgtcgag actggagaga
     1021 ttgacaacat cttcgacatt tttagaattt tagatttcta ctttcgggag gtggtcagct
     1081 gatgcagtac atttttcaag acgttgagag ggagttacac gagcgttagt aatgagtttg
     1141 tcaacgataa aaaactttat aacaaggaaa agggattgtt gttgaccatt cttagcaata
     1201 gcgatgagtg gcgagtatat ccggaggaat tggctaaacg ttgcagagat agtgttgacg
     1261 ctgtcagaac tcagctaaaa gcacttgaga aagctggata catcagaagt tatcggaagt
     1321 cgcttggcgg gcgatatggt accgaaaccc atagattttg ctcagacaca aaaataagtg
     1381 atgaggtttt tcaagagctg cttaaagaat taaattgcta atgtgcaaat tgctaatgtg
     1441 caaattgcta atgtgcaaat tgctaatgtg caaattgcta atgtgcaaat tgcctaacta
     1501 ataaatacta acactaaata aatactaaat aataataaat actaacaaac aataagcatc
     1561 atcatcaaca gcaggaggag ctatggacga aaaaaagctt tttgaaaatt ttcaactaac
     1621 tttcggaaga atgatatcgc catttgaaat agaagatatt caaaagtgga ttcaccagga
     1681 taatatgccg attgatgttg ttaaccttgc tttaagagaa gcggtagaaa acaacaagat
     1741 caattggaag tatatcaaca aaattttggt ggagtggcat aaagctggag atacgacgat
     1801 tgagaaggtc aaagagaggt tgcagagatt tgaggatagc aaagaacaac gacatgcaac
     1861 tatctcaaat gttcctagct ggtcaaatcc agactaccaa ggcccgacat acgatgattt
     1921 aaaagtaaat ccaagcgagg tgtcagatgg cgcaggagat ttttgatgga tttaatgcct
     1981 taatcaataa aatgtatggc agacaatcta gcatagagac ctttaaccga tttgtcgagt
     2041 attgtcaaaa aaggagagag gaaaacgggg ttgagcctgt attaaatccg atcaatcttt
     2101 ttgcattcgg cgttggaatc acaacggaag aagctaataa attaagaata aaacgctaca
     2161 aacaggagaa tggattatga caaaacaata tcgagagaca cttatctggc atcgggcaag
     2221 tcacaaagag cgtgagaagc tgcttgattt cgggctagtt gataaatcac agtacatgac
     2281 actattacgc caattgcgca agaaatatgc gatttaggag gaaatatgac accagaacaa
     2341 gtggaaaaag caaaaatcag agctaaacga gaacttgaaa cgtttagcat ctaccttgac
     2401 caggcgattg tcgaatacgg aagtacgcta agtccacaag aagtcttttt agcggcaggg
     2461 tttgcctacc ttggtgcagg tcagactgac atacatgcgg ccatcgaggg gttatatgag
     2521 caaatccaat gattttaatt ttagcgatga ctgggaaagc aactatttcg aggtccaagc
     2581 tttgctaggg caagagatag acaagctcca aaacagggtc atagcgctaa gccaggaaaa
     2641 caatagatta aaagcgagga aatgaaatgg caagtgaaat tgtaacaatt caaaaagata
     2701 tcactgatat cgttaattca aaaattagta tgcttcagaa cgaaggtctt gtaatagcgc
     2761 caaactatgc tccagcaaat gctttgaagt cagcattctt taaaatttta aaaaccaaag
     2821 acagaaataa gaggcctgct cttgaagcct gcacaaagga ctcaattgcg aactcgctcc
     2881 ttgaaatggt cacccaagga ttatcacctg caaaaaatca atgctatttt atcgtttacg
     2941 ggaatgagct ccaactgcaa agatcatatt tcggaacaat ggcagtttta ttgcagcaga
     3001 aaaaaattaa atcaattaag tcagaagtta tttatgaagg tgacgatttt gagcttgaaa
     3061 ttgtagatgg tgaaaagaaa ttcaaaaagc atgatactca ttggaaaaat caagacaatc
     3121 caattgaagg ggcttattgc attattgagg atatagatgg taacactaag ctaacactga
     3181 tgacaaaaaa agagattgat aaagcgtggt ctaagacaaa gactggtgga gggacacaaa
     3241 aagaattccc tcaggaaatg gccaaaaaaa cagttatcaa cagagctgct aagtttttta
     3301 tcaatatcag tgatgacagt gacattttgg cagattctat taacaagacc accgcagatg
     3361 aatatattga cgatcgtcaa gtaaaagatg taacggaaac acagtcacct gcacagacac
     3421 tactcgataa catgaagcat gacgaggaaa tgagcaaaat cgaaacgatg caaaatgaac
     3481 aattgatgca tgatccagaa acaggagaaa tcattgatgc agaggttgtt gaggcggacc
     3541 taaaggaatc tgatatggag gagccattct aatgagcgaa aatttaacac tttttgaaaa
     3601 tttaaatgac attaaaccag ccgaacccgc tgagctgagt tttgattttg agtttactcc
     3661 agccgaaatc aaaatcaaag ggaaagagaa gctcgaagag attttagcag cctacgctaa
     3721 aaaatacgat ggctacacag tgacagccga aacctttgaa gacgatgcaa aggttagagc
     3781 aaaactcaat actttgcaga aagatattaa taactctgta aaaacaaaac tcgcagaata
     3841 caataaccct cttgatgatg ttaagcagtg ggttaactca attattgagc caattaaaaa
     3901 aattacaaaa acgattgatg agggtgttaa acactttgaa gaaatcgaac gtcagaagcg
     3961 tgcaaataca atcaaagaaa cctttgaggc tgctattgct gaaacaggtg ctgatattga
     4021 tatccgcttg ttcgaatcta actttgacga tatgtcggct aaaggatatt ttatggctga
     4081 caacgtccgc gtcaataccg ctaccaaaaa ggccattaac aaattggttg ctgaagaagt
     4141 agcaaaaaaa caggaacatg agcaggcgct tatccaaatt tcagaagctg ctgccaaagc
     4201 ggattttgga ccagctatct atatcaaacg atttgaaaat ggcgcacaac tggcagatat
     4261 cttacaagca atcgctgacg ataaactgct tgctgacaag gtgcgcgaag aagaaaaacg
     4321 caaagcagaa ctatctaagc gagtagaaga aatgacagcc ctggcacaac gtgaagggtt
     4381 gcaaccaggc aaatatgtaa aattgcttga agatggcaag tctgctttag tcgtttttga
     4441 aactctgatg gacgattcta aaaaaatgca ggccaagata gcacaaaaaa acgcagaagc
     4501 gcatcagcaa caaatagaac agaccgaata tatgtctgag gcctcaaatt cgggggtaaa
     4561 cgagcttgaa acagacaagg tgataaataa tatcatcaaa caagaaaatg ccttagaagc
     4621 caaaatagaa ccgaataaga gcgtcacaaa atggcaaggt gattttaaaa taactttccc
     4681 ggattcagaa acagctaaac tatttggcgg gcaaggcgga ttatacgaaa agcatggcgt
     4741 gattgttgaa aaattaggtg aatgggtgaa gattaatgac taaattaacc gaagaaaatt
     4801 attatcaaga ccgagaatgg ttgtctaact caagatttaa ggctttcctt gattgtgagg
     4861 ctaaagcttt agctgtcgaa aacaacgagt gggaagatac cagagatgag acaccgcttt
     4921 tggttggtaa ctaccttcac agctatttcg aaagtcctga agctcatgag aaattcaaag
     4981 ccgagaatgg agctaagatg atttccagtc gtggagttac aaaaggggaa ctcaaaaaag
     5041 agtacaaagt agcgcaaaac atgattgaaa cgctagaaac tgatgagata tttaatctca
     5101 tgtaccatgg ccaatctggt gataatgttt tgaaagaaat gatcatatac ggggaaatct
     5161 taggcataaa agttaaagga aaagttgatt caatcaattt aacaaaaggt tatttttgtg
     5221 acttaaaaac gatgaaaagc atacacagcg acgaatggag taatgacttg cgtaagcgtg
     5281 tacctggtgt agcagctaac attatcgggt ttaaatacca tatccagatg gggctctatc
     5341 aagaattact cagacagatg actggaaaaa cgcttcaacc gctaatcatt gcaatcagta
     5401 aagagaatgt accagataag gaactcatcg aacttggcca aacgtggcta gatgaagggt
     5461 tgcaactttt tgaaaacaat gtggagcatg tgcacgaagt catcattggt aaagctgaag
     5521 ctaagtcgtg tggacgttgt gattattgtc gaagtcagaa aaagcttaat agggtggttg
     5581 atctcgatga tttgattgca ggaatttttt aggagatctt attgtattgc aaagtgatgc
     5641 tcggcctttg cagcaacaaa tattttccga gcgagaaagg aaaattgcaa tatcgtcaag
     5701 ttaacaggat tgatgatata aagagttgct acactcgtcc ttgctaatgc tcacacacaa
     5761 ttttagggcg agtgtggatt ttaaaaaggt gaaaatatgg aacaaatcaa aattacagga
     5821 actgacacaa tattaatttt agatagagta gatagggcct ttgtcattga gggtaatcta
     5881 gctgaaagat ggcgttttac tagcaagttt ataaagattg acgatgagct atcgctggac
     5941 gaggacggcg aattgtttga gatagtttat gacttaatgc tagaagcaaa acctcacaac
     6001 gtgattaatc taacatcatc atattttgct aaagaacata agaaagacac agatgaaatc
     6061 ataaaagtat ttgcttttat cgaagataac aagaagaata tttttgaaac ccttggcatt
     6121 cgcggggtgc ttgaatgagc aatctagtat tatcgctaga catctcaaca tctggtacag
     6181 gttgggcctt atttaaaggc tcagacctta tccagagcgg tgtcttaaaa cataagagcg
     6241 actcttattt tgaacgtgga cgctatatgg ctagcaaatt aaggttgatc cagtcacgag
     6301 ca
//
LOCUS       DARYVE010000087         6176 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYVE010000087 DARYVE010000000
VERSION     DARYVE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6176
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(37..1368)
                     /locus_tag="TVW25_001833"
     CDS             complement(37..1368)
                     /locus_tag="TVW25_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1379431.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TVW25_001834"
     CDS             complement(1459..2238)
                     /locus_tag="TVW25_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1379432.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TVW25_001835"
     CDS             complement(2269..2913)
                     /locus_tag="TVW25_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1379433.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TVW25_001836"
     CDS             complement(2919..3569)
                     /locus_tag="TVW25_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1379434.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TVW25_001837"
     CDS             complement(3584..4774)
                     /locus_tag="TVW25_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1379435.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4966..5868
                     /locus_tag="TVW25_001838"
     CDS             4966..5868
                     /locus_tag="TVW25_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1379436.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
BASE COUNT         1885 a         1423 c         1082 g         1786 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta ttatttttta ttgacagcta taaaaattat
     4921 tattagtatg aagaaaaaga catctgaaat gaaagaagag gcaatatgga tattaaacat
     4981 ttacgctttt tcattgctat tgtagaaaat aattttaacc tgagccgtac cgctcaacag
     5041 ctttatattt cccagcctac cctcagtatt atgattaatg attttgaaga aaagcagggc
     5101 attaagctct tcaataaaaa atacaataaa atcctcggct taaccatgac aggcaagcaa
     5161 ttttatgagg attctttgga ggttatccgc aaatatgaca agatgcacca aaatctcttt
     5221 tccaccaatc aaaagttgga cggtaatatc actatcggca ttcctccatt aattctgtca
     5281 attgtttttt caaaaatcat gccagaaatt attctagaaa atcccaatat ccactttaat
     5341 attaaggagt atggtgctaa tcggctacgt caggaattga ttttagagaa tgtggatatc
     5401 gccattcttc tgcatcctga acgaattgct gcaaacacca ttgattcttt ccaaatccaa
     5461 gaatctgagc tctgtgcatt tgtctccaag aaccaccatt tggccaataa aaaaatcctg
     5521 acttggatag aactccacaa tgaaaaacta gctatatttg ataaaacctt catgattcac
     5581 catctcatca aggaaaaatg taagtatact gacattaacc cccaaatcat tctggaatca
     5641 gcttcttggg actttctgat caattctact cgtatcaacc ctcaactaat gacgattatt
     5701 ccaaaaccaa cggtagatag ctatggtttt caggatattg tggctattcc tatggagaat
     5761 cctattcctt ggaaagtcat ggttagtcgt ctcaaaaaag atcattattc caccatagaa
     5821 gaatacattt tcaacaaaat gcttgaaaaa tttcatgtaa tcgaatagag actaacaagt
     5881 gatccctttc acatgactgc acgtgccctt cgacatatgg cacctcaact aacccttagc
     5941 gcatatggaa acagctcaat tctttttgaa ggataaaact aaagaggctt gacgatccat
     6001 actaactcag acccaatatt attatcaaga tcctaaatat taacacaact catttataac
     6061 aattaactta caaaaaatgg tctactcctt tgaggcgtga cagcaatact gcaatttata
     6121 aaaaatgact gtcaagacaa tatctctgaa ctcagtcact gtttctcaaa aatcac
//
LOCUS       DARYVE010000088         6010 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYVE010000088 DARYVE010000000
VERSION     DARYVE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6010
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            78..293
                     /locus_tag="TVW25_001839"
     CDS             78..293
                     /locus_tag="TVW25_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1379437.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            293..1156
                     /locus_tag="TVW25_001840"
     CDS             293..1156
                     /locus_tag="TVW25_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379438.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1229..1723
                     /locus_tag="TVW25_001841"
     CDS             1229..1723
                     /locus_tag="TVW25_001841"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1379439.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1727..2137
                     /locus_tag="TVW25_001842"
     CDS             1727..2137
                     /locus_tag="TVW25_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1379440.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            2097..4574
                     /locus_tag="TVW25_001843"
     CDS             2097..4574
                     /locus_tag="TVW25_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1379441.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            4576..5601
                     /locus_tag="TVW25_001844"
     CDS             4576..5601
                     /locus_tag="TVW25_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1379442.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            5567..>6010
                     /locus_tag="TVW25_001845"
     CDS             5567..>6010
                     /locus_tag="TVW25_001845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1379443.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRT"
BASE COUNT         2295 a          805 c         1230 g         1680 t
ORIGIN      
        1 aaagtttaac gattggaaga gaagatttcc agtcgttttt ttatgaaaat aagtaaaata
       61 atgaggagga ataaattatg gatttttttg tacaggcagt aaatgtgctt aaaattttgg
      121 ttatggcaat cggtgcagga cttggtgcat ggggagttat caacttactt gaaggatacg
      181 gatcagataa tcccggtgcc aagtcgcaag gaatcaagca attgatgagc ggtggaggaa
      241 ttgttttaat agggctgaaa ctaattccgc tacttgctaa tgtcttgaga taatgtttga
      301 tttatttgga aagatagaag agtttttcaa ggatattatg attgatatta ttaaagataa
      361 tctttctgca atgcttgtgg atattaatga taaagtagga accgttgcag gagaagtggg
      421 aaagactccg agttcttgga actcggaggt cttcaccttc attaaatcaa tcaataccaa
      481 tgttgtttta cccatagcag cgataattct aaccgcaata ctttgcatag aactgattca
      541 ggtggtaatg agaaaaaatt ctatgcacga tacggatacc tttgaatttt ttaagtacat
      601 tattaaaatg tggatagctg tatggcttgt gtctcatgcg tttgattttt caatggcagt
      661 ctttgatgtg gcacagtcca tgataggaaa ggcagcaggt gttgtgggga caagtgcgaa
      721 tatcacaccg ggaaattttg atgctatggt agaagccctt aaaacaaagg aacttggaac
      781 actcattggg attgcactgg agacgggatt agttaaattt tctttaacga ttctatcaat
      841 cttaatcact gtaatcctat atggaagaat gattgagata tatatctatt gctctgttgc
      901 ggcaattcca ttttctacga tgggaaataa agaatggtca aatatcggaa caaactatat
      961 aaaaagtcta tttgcccttg gacttcaggg acttttcatc ctaatatttt ttggaattta
     1021 cgcagtctta gtcaaaaccg taaactttac ggatatccac acaagtattt tacaggtatt
     1081 ggcatatgga ttgattcttg gagtaatgat gatgaaatcc ggaagtatag caaaggcgat
     1141 tttaaacagt cactaaagga ctttagttca aaatgagcaa aagttgatga aataatcaga
     1201 acaaaaaata taattattgg aggtaagaat gaataaaata aataaaaaaa caaggatttt
     1261 gataggagca ggctcagccc tttctatcgg gacaattatt acagtgctat taaaaaagaa
     1321 aacgaaaaaa ttatccgatc ttgaagaaga tgattttgac tttgattttg atgaaataga
     1381 agaagattct tgtgtcaacg ataaatttgc tacagaaaat gataaagatg atacagtaaa
     1441 aggagaaata gattttttag tagatgaatc aaagacggag aacgaaaagc aagaagagtt
     1501 tagagattta tcggtaaagg taatggatct tcttctaaaa gaagtaattt caatgagtga
     1561 aaccttaaat ttggtaaaaa gagatattga tagaataggt gaagtaaaag cattggttga
     1621 agaactggaa aactgtaaag aagaaattat ctcactttgg gagcacatgg aaaagttatc
     1681 cgatttaaga gaagaaatta ccggcaaaaa gaatagaggt taggctatgg cttatgtaaa
     1741 gataccaaaa gaccttacaa aagtaaaaac caaggtagcc ctgaatatga caaaaaggca
     1801 gcttataggt tttagcatag cagggcttat cggttttcct gtatatatgc tgtgtaaaaa
     1861 ttttcttagt acagatattt ccatgattat aatgagtata gtagttctac ctgttctttt
     1921 tgtaacgctt tatgaaaagg acaatttacc ttttgaaaaa catttagcat atatcctcag
     1981 gtttcataaa agtaaaaaga tcaggctata taaagcgagg agcatttatc atacagagag
     2041 agcaaaaaag caagatatag gaaataaaaa taaggcaagc ggaaggagga aaaaagttga
     2101 acaaagacaa aagaaaaaaa caggaacaac gaattaaaaa ggatgagttg gagcttagga
     2161 aaaatagaaa ggagctatcc gaacttaaaa aaacaggaaa gaaaaaaaca aagtctaaaa
     2221 caaaagggaa atcatcgaag aagaatgggt ggtttccttt ttttatgaaa gaggagaaaa
     2281 aagaaaccgt acaggatacc attccatata agcgaatgtt aaaagacggg atttgtcaaa
     2341 ttgaaaagaa taagtttaat aaaaccattc gatttttgga cattaactat cgcttaatgg
     2401 aagaaataga ccaagaggga atattttcgg aattttcttc ttttctaaat ttctttgact
     2461 catctgtgga agtggagttc agctatatca acagtatcgg agaaaatgaa gaaatcaata
     2521 aactgattga tattaaggaa aatatagatg attttaatga aattagaaac gaatatagac
     2581 aaatgctctt aaatcaaagc agcaaaggga ataatggatt atcaaagagt atgtacatta
     2641 cctttaccat agaggcggag gacttaaagc aggcaaaaag tagattagag cgaatggaaa
     2701 tggatgtatt aaacaacttt aagcagatgg gagtgaaagc ctatgtgtta gatggagagg
     2761 aaagacttaa aacaattcat gacattttaa atccaaatga taaacttgtt ttttcctttg
     2821 aggatttgaa atacagcgga ctgacgacta aggaatacat tgtacctccg tcttttaact
     2881 tttccaagcc gacgtatttt aagacaggag aagtctttgc ggaagtaaat tttttacagc
     2941 ttttagcatc agatattaaa gatgagatgt tatcagagtt tttggcattg gaagaaaata
     3001 tgattgttac ttttcatatc agagcaatcg accagatgga agctattaaa catgtaaaaa
     3061 gaaaaataac ggatttggat aagatgaagc ttgaggaaaa caaaaaagct attcgtgcgg
     3121 gatatgatat ggatatcttg ccaagcgacc ttgtaactta tggtgcagag gcaaagaact
     3181 tgctatcaga actacaaaac catgatgaaa agatgtttct cataacaatt ttatttatga
     3241 acacgagtaa aagtaagggg aaactcgata atacggtatt taccttaaag tccattgcaa
     3301 atagacataa ttgtagtttg aaaaacctaa attatagaca agaacaaggg cttgttgcaa
     3361 gccttccact tgggataaat gaagtggaga tagaacgagg acttaccaca agtgcagcag
     3421 ctatttttat accatttaca acagaagaac tctttatcaa gggagaaagc ctatattacg
     3481 gactaaatgc actaagcaga aatattatta tggcggacag gaagaaatta aagaacccaa
     3541 atggtctaat cttaggaaca ccgggttctg gaaagtcctt tgcagccaaa agagagatta
     3601 ctaatgcgtt tttgattaca gatgatgata ttatcattgc agatccggaa gcggaatatt
     3661 ctccgcttgt agaggcacta aaaggacaag ttatcagaat ttctccgatt tcaaaagact
     3721 atgtcaatcc actggacatc aatattgact atgcggatga agataatcct ttgtctttaa
     3781 aatccgactt tattttgtcc ctatttgaat tggtggttgg agaaaagaaa ttaagtgcag
     3841 aagaaatttc tgttatagac cgttgtttac caattttata taaaacctac tttgaaaatc
     3901 ctgtgccgga aaatatgcca attttagagg atttatataa tcttcttcaa aaacaggaag
     3961 aaatagtagg aaaaaagctt gcagtagaaa tggagatcta tgtaaaagga agtcttaatg
     4021 tatttaatca tagaacgaat gtagatacaa ataacagagt ggtttgctat gacatcaaag
     4081 aactgggaaa acagcttaaa aagataggaa tgttagttgt gcaggatcaa gtttggaata
     4141 gagttacaat taacagagca agtaaaaaag caaccagata ttatgttgat gaatttcatc
     4201 ttttgttgaa agaaccgcaa acagccaatt attcgattga aatctggaag cgtttcagaa
     4261 aatggggtgg tatgccaaca ggacttactc aaaatatcaa agaccttctt gcaagcccgg
     4321 agattgaaaa tatttttgat aatacggatt ttattttaat gcttaatcaa gcaggaacag
     4381 atagggatat tttagccaag aagctcaata tctccaagca tcagctttct tatgtaacaa
     4441 attcggggga aggagaagga cttatctttt atggaaatac gattgttcct tttatcgatc
     4501 agtttccaaa aaatacaaaa ctatattcac taatcacaac caaacctgaa gaagtaaaaa
     4561 aggcaggtga ataggatgag tgtgagcaga agtaaagagg aattcatcaa agaaaataca
     4621 aataaaatta tttgttcgga tgcacttgaa actttaagaa aaattccaga cgaaagtata
     4681 agctgctgca ttacatctcc cccatactac aggctcagaa actatcataa agaaggtcag
     4741 ataggaagag aatctacagt agaagaatac ttggatagat tgttacaggt atttcgtgaa
     4801 gtaagaagag ctttaaaaaa agaaggtact tgctttatcg taattggaga ttcttatgct
     4861 gattcaggag gtggaaaggg acaatacatt gatcctaaat atccaaaggc aagaaatgga
     4921 agtaacgctt tagctacaga aaatatctca gggtacaagt caaaagattt aatgggaata
     4981 ccttggagat tagcgttact tctaagagag gatggttggt atctgcgttc tgatattatc
     5041 tggcataagg aaaatgctat gccggaggcg tgtagagata gacctactcg ttcctatgaa
     5101 catatttttt tacttacgaa atcaccaaaa tactattatg actatgatgc tatggtagag
     5161 ccgatgaaag aagtcagtaa aaaaagatat gtaagaggaa gaaaatcgga taataaatat
     5221 ctgaaagaaa attccggagc aaagttgcaa aaaatcaatg aagcaagaaa atatggagaa
     5281 tataagggcg ataatgtccc gcagtttcgt aataaaagag atatttggac tatcaatacc
     5341 acatctttta gaggcaatca ttatgcaaca tttccaccga aacttgttga gatttgtatg
     5401 attgcaggtt gtcctaaaaa tgaaattgta cttgatcctt tcattggaag tggaacggtc
     5461 ggatttgtgg cacttcgtca taacagaaag tacattggaa ttgaattaaa tgaggagtat
     5521 gtaaatcttg caaagaatag aatcagtgag gaggtgaaaa aatttaatga agaacaaaaa
     5581 caagaggtac aaaaagaata gagaaaaact cttaaatcaa gaaatacagt ctttacaatc
     5641 tcaaactcaa gataattatg aaacaggatc ctcaaaaaat cagaatgaaa ccttgctgaa
     5701 agacgaaact tacgataaga aacaattttt atctgaaaag aagttatcca atcatttgga
     5761 taatagacat ataaataatt attcggatag aactatatct tcttattgct tgtcggatac
     5821 gggaaatata aatcaaaata ggtcttcctt tcaagctgaa aaacataaaa aaaagatgca
     5881 aaagcagata aataaatttc aaaagggaga aaaggaagtc tacgatcctt tatcaaaaga
     5941 tatggataat gatggtgtaa tagacaggta tgatgtggat tttagggata gcaaagtatc
     6001 atatcgaact
//
LOCUS       DARYVE010000089         5578 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYVE010000089 DARYVE010000000
VERSION     DARYVE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5578
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..935
                     /locus_tag="TVW25_001846"
     CDS             <1..935
                     /locus_tag="TVW25_001846"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379444.1"
                     /translation="FSLNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVARE
                     KLINTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDN
                     GAVSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGR
                     GKSGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSF
                     DQIGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSM
                     ESTGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            937..1443
                     /locus_tag="TVW25_001847"
     CDS             937..1443
                     /locus_tag="TVW25_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379445.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            1587..2009
                     /locus_tag="TVW25_001848"
                     /pseudo
     CDS             1587..2009
                     /locus_tag="TVW25_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2538..3263
                     /locus_tag="TVW25_001849"
     CDS             2538..3263
                     /locus_tag="TVW25_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1379446.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            3253..4764
                     /locus_tag="TVW25_001850"
     CDS             3253..4764
                     /locus_tag="TVW25_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1379447.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            4766..5281
                     /locus_tag="TVW25_001851"
     CDS             4766..5281
                     /locus_tag="TVW25_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1379448.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
BASE COUNT         1648 a          924 c         1305 g         1701 t
ORIGIN      
        1 ggtttagctt gaatgagcca atagcagcta gggtgacgaa accgacctac aaccgccagc
       61 agcttttgaa gaaccttgaa aacagcaggc tggcaacaga gagctcaagg tttaagagct
      121 atgtagcaag agaaaagtta attaatactt taagaaaaca gaatgctgat ctaaatctta
      181 tcacatttag ggagaaagcc atagaaattt ttaataggga tcttaaagga aatagttggg
      241 tttcgataag acaggctgat gaatttgtag aaacattaga tgattatgct caattatcag
      301 tagataacgg tgctgtttct acaaaagcag atttttataa gatgtattca aataagaact
      361 atatatattt agatggcttt ataaagaata taaaacagct ttatattaag acaggtgcat
      421 catcaattgt gaatggtcaa gatttgtata atgcaattga gcaatatggt accattggaa
      481 gaggtaaatc gggaaatttt gcaacaagta tggctgaaga tatagcatta ctttatgata
      541 gtagtggtaa tttagtttct tccggtatga tagaggctat caaaggggta gatgaaggta
      601 agtatttgtc tggtgcattt cagtatgaat atagtcctca gtttgttaaa tcttttgatc
      661 aaatcggtga agtgagaaca gttactggta aaactccagg ttcttcactt ttaaatattc
      721 caggggctaa aacttgggca ggtaaaaata tggctttgtc acagtctgaa ttaatgatgc
      781 catctattga tactagtaac ttaaaattgg aggatgtatt attaagtatg gaatcaacag
      841 gaatttatac cttgaataat cctacaatcg ttttgaaaga tggcactaaa aagattgttg
      901 aaggacaatt tataattaga aaattaggta attaatatga cacaaacatt ttttaacaat
      961 gacgttgatg aaagacgtcg acaactttac ttagatgctc gttcaaaggg acacttagag
     1021 aagtgcttta gaggggattc tgggtttaaa ataaatgcta aagactcata ttttcaatcg
     1081 atcacagata taaatgtgct tattgagcgc tgcttgtatc ccttgtatga tttaggagat
     1141 agcattatcc cacatgaaac tgaaagaata ctgtctcaat tctcaacttc aaaaaatgtt
     1201 gtagaattat atcaagttgt gtcatatatt ttctatcaaa agaacaacaa actactaaag
     1261 aagaactttt ccttttatat tgattttaat cctatgatcc ctgatttagt tttttctgtt
     1321 aaaaggttat ctcctgaaaa tatcgtgact gatgatgaaa aagcgatggt tggttttata
     1381 aaaaacatgt ttcaaaaaat tcctcaggta cagtcttatc ttgaagctca aaattgcaaa
     1441 tagtttagat gaatacttga aaaatggatt tgaaatagct taaataaaaa tagagtatgc
     1501 ttttcaatca gacgaggtaa gggtattatt ggaaaaagat tgagcagtat ttatcgatta
     1561 agctataaaa acgaaagata acacacatgg cacgcagtca attaacatgg gaagatgtta
     1621 gtcaatatga ggaaatcaag ggttatggcc aacaggtttg gaagcatcag ggagaatatt
     1681 atctagtcag agaagaagga ggaattgctg tacaacgagt agtgtataaa ctccctaatg
     1741 agcttttcca attactggaa agtgaccgaa aatttttatt agaaatagat ttttatgtca
     1801 aaaataactg ctggctgcca acagaagagg agaaaatagc tagtgataaa gcatttctac
     1861 aaagatcccc aatagcatta attgcagatc caaccagttg ggaactgttt acctaagaag
     1921 agctaagaaa actaattcca attgcggagc aaaaatggat agattggaag ggaaaactgc
     1981 cagatgatta tgtcagtcct ttgaaataat gtttaagata gcggatctga gggcagctat
     2041 gttaggggcc gttgttagct gtattaggta ggtgaaaagt ggttattttt gggtacaatc
     2101 aaaagttcta tatataaccc ttgcggtgga gttacccact acgggtattg tagagcttga
     2161 aaagctgggt gcgagagagg actggactgg ttctctcttt tttgtctctt tgtcaagctt
     2221 atcaagcaat aataggacct aaggtagttc ttgttgagac atattgccgt atttggcctt
     2281 agctggctgg caaaaaggct tttatggtaa gaaggtatgt cttgtaaggt tttgctgttg
     2341 ttgtatcaat tagtaaatag ctcaataggc tagctctttg ccatacttaa ggctattgaa
     2401 tatactttca gaaaacaagg atttttctct gaaaatgaaa gtacttccta aaagtgggct
     2461 gtctattgaa agtgttttaa tatctgctac aataaagatg tgaacgttct ctaaaattaa
     2521 taaaaggagt agaaagcatg cttgaaaaac caagcaaggc agagctactg acagctctga
     2581 aagacgggct gatcgtttcc tgtcaagctc tgccgggcga gcctctctat tcagaggcag
     2641 gaggtatcat gcctctgatg gcaaaggcag cagaggaagc aggagcagta gggataagag
     2701 ctaatggggt tcgagatatt aaggaaatcc aagcggtgac ggatctgcca atcataggga
     2761 tcatcaaaaa ggagtatcct ccgcaagcgc cctttatcac gccaaccatg gcagaggtag
     2821 acgccttagc ggccttagat gtagcggtga tagccttgga ttgtacgcaa agggagcgtc
     2881 atgatggctt agcgatagcg gactttattc gatcgataag gaagaagtac ccagagcagc
     2941 tgtttatggc agacatcagt acgcttgaag agggtctagt agcctatgag gctggtatag
     3001 attttgtagg gacgacctta tcagggtata cgccttatag tcgtcagggg acaggtccgg
     3061 atatggagct gataagtgcc ttgtgtgatg caggggtatc agtgatagct gagggcaaga
     3121 ttcatagtcc agaggaggcc agggctgttc aggctttggg agtagctggt attgtggttg
     3181 gtggtgctat taccagacca aaggaaattg cagagcgctt tgtggcggct ctcaagaagg
     3241 aggagaaatc acatggattt taagaaattt tcaaaattgg gtcaagcctt tatgctgccg
     3301 atctcaatct taccagttgc tggtttgttg ttggggattg gtggggccct gtcaaatagc
     3361 aatgccattg cacaatttcc gatattaaat caagcatggc tacaggctat ttttaccatt
     3421 atgagcacag caggtaacgc tgtttttgct aatattgcct tgatttttgc gattggtgtt
     3481 gctgttggct tagccaacgg agataaagga acagccggtc tttcaggtgc tgtggcttat
     3541 ttggtcttta cggcaaccat tagcggctat ctgactcttt tttcagcaaa ggacgctcag
     3601 attgatacgg gtgttttagg ggctttgacg gttggcttag ttgttgttag ccttcacaat
     3661 aagtaccgaa agatcgaact gccagccttt ttaggcttct ttggcggctc tcgttttatt
     3721 ccgattgttt cctcattggc agcgattgtg attggtagtg ttttctatgt catttggcca
     3781 cctattcaaa atctcctagt agtgtttggt gaaaaaattg cggatatggg gagcatcgga
     3841 acattcttgt acggtttctt tttacgtctg acaggagcag tagggctgca ccacaccatt
     3901 tacccaatgt tttggtatac atcacttggc ggtagtgagg ttgtagcagg tgagactatc
     3961 caaggagcac aaaatatctt ctttgcgcaa ttggctgatg ctaaccatac cgacttgttt
     4021 acttacggga cacgcttttt tgcaggacgt tttgcaacca tgatgtttgg actacctgct
     4081 gcctgtcttg ctatgtatca cgctattcca aaggctaatc gtaaaaaggt tggtagcttt
     4141 tattcaagta gtgccttgac ttccttacta acagggatca cagagcctat tgaatttgcc
     4201 tttttatttg tagccccttg gctctatgta gttcatgctt tcttagatgg ttgttctttc
     4261 ttagttgctg atttattaaa gattcgtatc ggtaattcct tctcaggtgg tttgattgac
     4321 tttttaatct ttggtgtgtt ccaaggaaat gatcatacca actggctact tgttatccct
     4381 gttggtatcg tgtggtttat ggtttattac tttgtcttta aattctttgt gagcaaattc
     4441 caggttgctg taccgggaat ggtagctcag gtagaagcag aaggacaagc agagactact
     4501 aatactcaaa gctcatcact tcgtgaggtg tcattagcta ttattgaggc tttgggagga
     4561 caagctaaca tcgaagatgt aaccgcttgc gcgactcgct tgagagtgtc tctgtcagat
     4621 agcagcttgg ttaacaagaa tgttttaacc tcactgggag caacagctgt attagatgtt
     4681 aaaaatggca ttcaggctat ttatggtggt aaggctatct tgtatagtca agaaatcaat
     4741 caactattag gtagagaaga ttaacatgat aaagaagtgg aagcaattat tatcagcaaa
     4801 aaaagctgat gcgttaagcg atcgtatttt atcagtggct aagggacaat tagttcctat
     4861 taccagtgtc agtgatcctg tcttttcaga aaggctaatg ggcgatggct ttgctattat
     4921 tcctcaggag ggcgctattt atgcacccgt aacaggaagg gtcatgacgg tttttccgac
     4981 caagcatgct tatggcatcg ttactccagc tggtcttgag gtcttgattc atatcggtgt
     5041 tgatactgtt gagctgggag aagctgcctt tagctctgat attgttgctg gtcaggaggt
     5101 agtagctggg cagttattgg ctcaggtctc tttgccagtg cttgaagctg ctcaaaaaga
     5161 cagcaccgtt atggttgtct ttacaaactc acaggacatt gctgatatgc gtcttgctga
     5221 tgctggagca gttgctgcta gggcagaagt cggccaagtt aggctaaagg ctactctcta
     5281 gctagaggct atcgatccag tccttgatga caactaaaag gtcatatgaa aaaactgcac
     5341 cccagcactt ggctaagtcg gtcaatgcct tggggtgctt ttattattgt cagcaatcag
     5401 caggctttga ttgtcctatc ttttaacctc tatttaaatg ttaacagctg tcgtatgtgc
     5461 cttgtggcaa ataaaagaaa agctcagcga cctgtttctc atattgctta gcacatttta
     5521 ttttaggggg gctattatat cctccccagt atacaagggc tgaaaaagga aaatagag
//
LOCUS       DARYVE010000090         5468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYVE010000090 DARYVE010000000
VERSION     DARYVE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            227..1780
                     /locus_tag="TVW25_001852"
     rRNA            227..1780
                     /locus_tag="TVW25_001852"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2002..2074
                     /locus_tag="TVW25_001853"
     tRNA            2002..2074
                     /locus_tag="TVW25_001853"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2035..2037,aa:Ala,seq:tgc)
     gene            2382..5281
                     /locus_tag="TVW25_001854"
     rRNA            2382..5281
                     /locus_tag="TVW25_001854"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5366..>5468
                     /gene="rrf"
                     /locus_tag="TVW25_001855"
     rRNA            5366..>5468
                     /gene="rrf"
                     /locus_tag="TVW25_001855"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1577 a         1102 c         1576 g         1213 t
ORIGIN      
        1 tcgtatacta gtgaagctgt cggcgagcac tagctcaagt taatgaaaaa aaggtaaaaa
       61 aagtagttga caaaggcagt ctaagctgat agaatgtaat agttgtctcg tgagacaaag
      121 acctttgaga actgaataag acgacctaaa cgtgcgggtt acggaagtaa cctgtcaata
      181 aagaaacaag tcagtaatga cgtcgagtta agagctcaaa cactgaatta acgagagttt
      241 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtgg aacgcacaga
      301 tgatacgtag cttgctacaa ttatctgtga gtcgcgaacg ggtgagtaac gcgtaggtaa
      361 cctagcttat agcgggggat aactattgga aacgatagct aataccgcat aaaagtggtt
      421 gacccatgtt aaccatttaa aaggagcaac agctccacta tgagatggac ctgcgttgta
      481 ttagctagtt ggtagggtaa aggcctacca aggcgacgat acatagccga cctgagaggg
      541 tgaacggcca cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga
      601 atcttcggca atggggggaa ccctgaccga gcaacgccgc gtgagtgaag aaggttttcg
      661 gatcgtaaag ctctgttgtt agagaagaac agtgatggga gtggaaagtc catcatgtga
      721 cggtaactaa ccagaaaggg acggctaact acgtgccagc agccgcggta atacgtaggt
      781 cccgagcgtt gtccggattt attgggcgta aagcgagcgc aggcggtttg ataagtctga
      841 agttaaaggc agtggcttaa ccattgtatg ctttggaaac tgttaaactt gagtgcagaa
      901 ggggagagtg gaattccatg tgtagcggtg aaatgcgtag atatatggag gaacaccggt
      961 ggcgaaagcg gctctctggt ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac
     1021 aggattagat accctggtag tccacgccgt aaacgctgag tgctaggtgt taggcccttt
     1081 ccggggctta gtgccggagc taacgcatta agcactccgc ctggggagta cgaccgcaag
     1141 gttgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc
     1201 gaagcaacgc gaagaacctt accaggtctt gacatcccga tgctattctt agagataaga
     1261 agttacttcg gtacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga
     1321 tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt agttgccatc attaagttgg
     1381 gcactctagc gagactgccg gtaataaacc ggaggaaggt ggggatgacg tcaaatcatc
     1441 atgcccctta tgacctgggc tacacacgtg ctacaatggt tggtacaacg agtcgcaagc
     1501 cggtgacggc aagctaatct ctgaaagcca atctcagttc ggattgtagg ctgcaactcg
     1561 cctacatgaa gtcggaatcg ctagtaatcg cggatcagca cgccgcggtg aatacgttcc
     1621 cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga agtcggtgag
     1681 gtaaccgtta aggagccagc cgcctaaggt gggatagatg attggggtga agtcgtaaca
     1741 aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggaaaa aggaagcacg
     1801 tttagcgtct tatttagttt tgagaggtct tgaaataagt catgagaacg ttaagaaacc
     1861 cgtatgacaa tagggaactg acgcagagtc gtaggactca aggaagtgat tctttttcac
     1921 tagggtttta gttcgaatac agtttggctt catacagacc attgataaga gtatacatat
     1981 acaagtacat ttatagtgta cggggcctta gctcagctgg gagagcgcct gctttgcacg
     2041 caggaggtca gcggttcgat cccgctaggc tccattatct aggatacaaa gagaagtttg
     2101 ggttacctaa ttttctgtat tctaagatat ataagatata gttcaagtaa ttgaacacga
     2161 cctcattttt taggaaaaaa gataaatctc ctcgtgtgta aagcacacat cgtcgatttc
     2221 ctatttttct acaaaaatgc ccaacaagtt gggacggtct tagtatctta atcttgtcca
     2281 ttgaaaattg aataactata tcatattccg caatcaaaaa agattgtaag aaagtaacaa
     2341 gaaataaacc gaaacgctgt gataacgagt ttaaaaaata aggttaagtt aataagggcg
     2401 cacggtggat gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt
     2461 ggggagctgt aagtaagcaa agatccagag atgtccgaat gggggaaccc actagctaat
     2521 ggctagtatc cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta
     2581 agtagctgca ggaagagaaa gcaaacgcga ttgcctgagt agcggcgagc gaaaaggcag
     2641 gagggcaaac cgaagagttt actcttcggg gttgtaggac tgcgctgtgg gacgacaaga
     2701 ttatagaaga aggccttggg aagggtcgcc aaagagagta atagcctcgt attcgaaata
     2761 gtctttaacc ctagcagtat cctgagtacg gcgagacacg aggaatctcg tcggaatctg
     2821 ggaggaccat ctcctaaccc taaatactca ctagtgaccg atagtgaacc agtaccgtga
     2881 gggaaaggtg aaaagcaccc cgggagggga gtgaaagaga acctgaaacc gtgtgcctac
     2941 aagaagttcg agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt
     3001 acgtttatgt gcgaggttaa gttgaagaga cggagccgaa gggaaaccga gtcttaatag
     3061 ggcgtaagta cgtggacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
     3121 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
     3181 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
     3241 agggctagcg tcgatatgaa gtctcttgga ggtagagcac tgtttgggtg aggggtccat
     3301 cccggattac caatctcaga taaactccga atgccaatga gatatgatcg gcagtcagac
     3361 tgcgagtgct aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtcccc
     3421 aaataactgt taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag
     3481 aagcagctat tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa
     3541 aatgtaccgg ggctaaaaca gtttaccgaa gctgtggatt accgttaagg taatggtagg
     3601 agagcgttct atgtgtgatg aaggtatact gtgaagagtg ctggaacgca tagaagtgag
     3661 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggatt
     3721 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaagggtgta
     3781 tccgatggac aacaggttga tattcctgta ctagagtata tagtgatgga gggacgcagt
     3841 aggctaacta aaccggacga ctggaagagt ccggctaagc agtgaggtgt gatgtgagtc
     3901 aaatgcttac atctataaca ttgagctgtg aaggggagcg aagttaagta gcgaagttag
     3961 agacgtcaca ctgccaagaa aagcttctag cgatacgtat actctacccg taccgcaaac
     4021 cgacacaggt agtcgaggcg agtagcctca ggtgatcgag agaactctcg ttaaggaact
     4081 cggcaaaatg gccccgtaac ttcgggagaa ggggcgctga ctgaaggtca gccgcagtga
     4141 ataggcccaa gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta
     4201 tagggggtga cgcctgcccg gtgctggaag gttaagagga gtgcttagcg caagcgaagg
     4261 tatgaattga agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat
     4321 tccttgtcgg gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac
     4381 gagagactcg gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa
     4441 agaccccatg gagctttact gcagtttgat attgagtatc tgtaccacat gtacaggata
     4501 ggtaggagcc atagaagtcg ggacgccagt ttcgatggag gcgatgttgg gatactaccc
     4561 ttgtgttatg gctactctaa cccggatagg tgatccctat cggagacagt gtctgacggg
     4621 cagtttgact ggggcggtcg cctcctaaaa tgtaacggag gcgcccaaag gttccctcag
     4681 attggttgga aatcaatcgc agagtgtaaa ggtataaggg agcttgactg cgagagcaac
     4741 acctcgagca gggacgaaag tcgggcttag tgatccggtg gtaccgtatg gaagggccat
     4801 cgctcaacgg ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat
     4861 cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc
     4921 caagggttgg gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag
     4981 acagttcggt ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg
     5041 agaggaccag agtggactta ccgctggtgt accagttgtc tcgccagagg catagctggg
     5101 tagctatgta gggaagggat aagcgctgaa agcatctaag tgcgaagccc tcctcaagat
     5161 gagatttccc ataacgttaa gttagtaaga gccctgagag atgatcaggt agataggtta
     5221 ggagtggacg tgtggtgaca catggagcgg actaatacta atagctcgag gacttatcca
     5281 aaagatgaaa ccagtcgcta ttgacagctt aaggaattct tgttagacta tagttattca
     5341 attttgagtg gagaagactc gtaagttaag tgacgatagc ctaggagata cacctgtacc
     5401 catgccgaac acagtagtta agccctagaa cgcctgaagt agttgggggt tgccccctgt
     5461 gagatacg
//
LOCUS       DARYVE010000091         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYVE010000091 DARYVE010000000
VERSION     DARYVE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(150..389)
                     /locus_tag="TVW25_001856"
     CDS             complement(150..389)
                     /locus_tag="TVW25_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1379449.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TVW25_001857"
     CDS             complement(548..1036)
                     /locus_tag="TVW25_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1379450.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TVW25_001858"
     CDS             complement(1055..1345)
                     /locus_tag="TVW25_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1379451.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TVW25_001859"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TVW25_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1379452.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TVW25_001860"
     CDS             4640..>5325
                     /locus_tag="TVW25_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL1379453.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYVE010000092         5312 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYVE010000092 DARYVE010000000
VERSION     DARYVE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..505
                     /locus_tag="TVW25_001861"
     CDS             <1..505
                     /locus_tag="TVW25_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="anticodon nuclease"
                     /protein_id="HEL1379454.1"
                     /translation="KFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIEDEKQ
                     FKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYGRWE
                     NILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNSFDS
                     IYRFKED"
     gene            508..3603
                     /locus_tag="TVW25_001862"
     CDS             508..3603
                     /locus_tag="TVW25_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1379455.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            3771..5222
                     /locus_tag="TVW25_001863"
     CDS             3771..5222
                     /locus_tag="TVW25_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1379456.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT         1675 a          889 c         1177 g         1571 t
ORIGIN      
        1 gaaatttgtc gtctctactc atcaagcatt attttataat gtactttata atgaaatccg
       61 atttgataga agaatcaaga aaaaggtttt ttacgtcatg aaagctactg atgaaattga
      121 ggatgagaaa caatttaaat atttgttgac agatgttgaa ggggattctc catttggata
      181 tcatctcaga gtgagagaag aattgagaaa agcaattcaa gatgaacagg tagagaaatt
      241 ccattttgct ctttttagaa acctagttga aaaaacagca acatttttag gatatggacg
      301 atgggaaaat atcttgttag gtttagatgt tgctggacat gttataacat ctgaaaatat
      361 taaactctat acacaactga ttgatttata cactcataat aggcatgctg atttagaata
      421 tagagaattg cctccccaag agaaaaatac tcttataaat ttatttaata gctttgattc
      481 aatctatcga tttaaagagg actaactatg actgaaatca tccaaacaga tactatttta
      541 gaggctaaga acttcattgt actggaaaaa tacaccaagt tggaaaagcc tagcacctat
      601 cagacggaag cagacttgga gcgagagctg gttagcgatt tgcggcagca gggatacgag
      661 tacctcaaca atctgacgac cccagaagct ctcttagata acctaaagac ccagatggaa
      721 gcccttaatg gcgtggtttt ttctgaggca gaatggctgc gttttttaga ggagtacctc
      781 aataagccta gtgatggttt gattgaccgc acccgaaagc tccacgataa ccacatctac
      841 gactttatct ttgacgatgg gcatatccaa aatatttatc tctgggataa gaaaaatatc
      901 agtcgaaata agcttcaggt cattaaccaa atgtctcaag ttgggacttc aagtaaccgt
      961 tatgatgtga ccattttggt taatgggcta cccttagtac aaattgagct taaaaagcgt
     1021 ggggtggcta ttcgtgaggc tttcaaccag gttcaccgtt acagtaagga aagctttaat
     1081 gaggaaaatt cgctcttcaa gtatctccag atttttgtca tttcaaatgg gacggatact
     1141 cgctattttg ctaataccac taagcgagag aaaaattctt ttgactttac catgaattgg
     1201 gcactaaaaa ataatgagcc aatcaaggat ttgaaggatt ttacagcgac cttcttcagt
     1261 cagcagacac tcttaaacat tctcatcaac tactcagttt ttgatactag tgataccctc
     1321 ctaatcatgc gtccctatca gattgctgcg acggagcgca tcatctggaa gattcgttcg
     1381 gccattgata gcaaaatcaa gagtggtcct gagactggcg gctatatctg gcatacgacg
     1441 gggtctggta agaccttgac cagttttaag gctgcgagac tggcgactga gatggataaa
     1501 gtggacaagg ttttctttgt ggttgatagg aaagacttgg actaccagac tatgaaagaa
     1561 taccagcgtt tttcacctga ctcagttaat gggtcaaata gcacagctgg acttaaacgc
     1621 aatatcgaaa aagatgacaa taagattgtt gtgacgacga ttcaaaagct caataacttt
     1681 atgtctagtg aagcacagca tgagatttac aacaagcaag tggtctttat ctttgacgaa
     1741 tgccactgtt cacagtttgg cgaggctcaa aagcgcttaa aacaaaagtt taagaagtat
     1801 tgtcagtttg gttttacagg cacgccgatt aaagttgaaa atgctttagg cagtgagacg
     1861 acagcttctg tattcggtcg ggagcttcat gcatacgtca ttactgatgc tatccgtgac
     1921 caaaaggtgt tgaaatttaa ggtggattat aatgatgttc gtccacagtt taagtcgtta
     1981 gaaactgagc aagatttagg gaaattatct gctgctgaaa ataaaaaagc cctacttcat
     2041 ccaacacgga ttacagagat ttcggcttat attttagaac attttaatca aaagacacat
     2101 aggcaaaacg gtaaaggatt taacgctatg tttgctgtgt caagtgtcga ggcggccaag
     2161 gcttactacc aagagttgca agaccaacaa gctggaaaag ctaaaccatt gaagattgca
     2221 accatcttct cttatgcagc aaatgaggag caggctgcga ttggggagat tgatgacgag
     2281 actttcagcc ctgctgactt gtcagatatt agtagtaagg aatttttgag cggagcgatt
     2341 tccgattata atcgcctttt tcagactaat tttagtatca atggcaatga gtttcaaaac
     2401 tattaccgtg atttagctaa gcgagttaag tctggagaag tggatttgct gattgtcgtt
     2461 ggtatgtttt tgactggttt tgatgcacca accttgaata ctctttttgt ggataaaaac
     2521 ttgcgttatc atgggcttat tcaggctttt tctcggacga atcggattta taatgcgaca
     2581 aagacatttg gaaatattgt aactttccgt gatttggaga aggctacgac ggatgctatt
     2641 aagttgttcg ggaagacgga gacggctgat attctgttag agcgctctta cgaggactac
     2701 atgaatggct acattgaggc tggtcaagag caaaaaggat atttggaagt cgtaaaagaa
     2761 ttgcaggaga gatttccaga tccaacgact attatcaaag aaagtgataa gaaagaattt
     2821 gtgaccttgt ttggtcagtt cttgcgcttg gataatatct tgcagaacta tgatgatttc
     2881 atgagtttgc aggctttgca agagttagat gttacagata tagaggcttt ggcagatttc
     2941 aaaggacgtt ttcatttgga tgacgaagca gttgcagtac tctctcaact ggacatccca
     3001 agtgttcgtg agattcaaga ttatcgctcc gcttacaatg atatcaagtc ttggtatgac
     3061 aatgagcggc gtaatcagca gaataacgat tccgaaatcg actgggatgc ggttgtcttt
     3121 gaagtggagt tgttgaaatc acaggaaatc aatctggact atattctgga attgattttt
     3181 gaaaccaacc aaaaggtatc tgacaaggat caactcattg aagaaattac acgaactatc
     3241 cgtgctagtc tgggtcagag agctaaggaa agtttgatcg tggattttat caatgccagt
     3301 gacttggaca gtttttctga gaagtcagat atcttggagc aattttatac atttgcccgt
     3361 caaaaacaaa aagaagcagt ggctaatttg attgagactg agggattgaa tgtagagagt
     3421 gctagccgct atattcagat gtcactcaaa cgagagtatg ccagtgaaaa tggtaatgct
     3481 ctcaatgaag cacttcctaa gatgagtccg ctcaatcctc aatatcgtac caaaaagcag
     3541 atggtgtttg aaaaaattgt ggatttggtg gagatattta aggggattgg tggagaaatt
     3601 taattattat tatttcttct agatatagaa gagataaact ttaaattaga gcttgaaatt
     3661 ttaagaaata ttaaggcatc atatcagtag tataaaaagc tgacttataa tttatttgga
     3721 aacgacagtt aatcctaaaa tacgatgctt gatatggagg aggcttaaac ttggaaaata
     3781 aaaaggattt aattcaaacc ttagcctact accaattctc actagaaaac caatacttgg
     3841 atagaaaatc agcacgaaag aagccgcaag aattactcaa gcatctgatt gcttttgcca
     3901 atgcggacgg cggtcagttg gttattggta ttgaagatga gaagcaggac aatattatca
     3961 ctggtttcaa ggatggcaga gcttatccca tagacgattt caaaaaaatt gaccatgaga
     4021 tgcgggagac tcctctggat ttgtctttag aggaaatccc tgtgctaaat cataagggag
     4081 aagatgacct gattttggtt atttctgttg aattatcgtc gaaccgagtg attgctgcgc
     4141 ctaatgatga ggtttatctg cgtcagggcg atgaatcggt taaattaagc tatgagcaac
     4201 gtactcagct tagctatgat aagggccaac gtttctttga agatgaagtg gtacctgatg
     4261 cgaccttgga agatattgat gatgggttag tccaggactt caaaaatcgg tttgatattt
     4321 cagagcgctc catggaagaa gttcttaaag caagacgatt cttggttaat ggtaaattaa
     4381 ctaaggcagc gattctactc tttgccaaat atccatcagc gttttttcca caagctcgtg
     4441 ttcgttttca acggtttgac gggacggata tgggaacagg cagtagcttt aatgttatta
     4501 aagaagtaac ttttgatgat gctctgccca ccttaattat caaagtgcga gattttatcc
     4561 gtactcagct gcgtgaattt cagtacttag acgataatgg gcaattccag attttgcctg
     4621 agtatcctga atttgcttgg tttgagggtg ttgtcaatgc ggtgactcac cgtgattact
     4681 ctgtctatgg ggatcacatt cgtgtactca tgtttgatga tagactggag attcatagcc
     4741 cagggaaatt accaaatatc gttaccgttg acaatatcaa gcatgaatgt ttttctagaa
     4801 atcctcggat tgcgagaacc ctgactgaat ttggatgggt tcgtgagatg aatgaaggag
     4861 tgaagcgtat ctattctgag atggaatcag cttttcttca tgaacctaaa tatttagaac
     4921 caggtaataa ggtagttttg acccttgaaa ataacatcgt gagtcgacat ctccgaacac
     4981 gagatagttt ggaaaaacaa ttttctgatt ttggaaatct gactgcagat gaacaagcta
     5041 tcgttcacta catgtataat tctggcgata aaatgacaac agcaaaggcg attgagttga
     5101 cagggagaag tcgttcgttt gttgtcaaaa tgctacatca tcttcgtgat ttagaaatca
     5161 tcacttggtt tggttcaagt aaaaatgacc gtaatcaata ttatctttta gttgataaat
     5221 gattgcagcc aggatactta ttagtaataa gaatacagta gaatacagaa aaagtggtgt
     5281 tccataaaat attgatcacc acttttgatt at
//
LOCUS       DARYVE010000093         4568 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYVE010000093 DARYVE010000000
VERSION     DARYVE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4568
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            125..1837
                     /locus_tag="TVW25_001864"
     CDS             125..1837
                     /locus_tag="TVW25_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1379457.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            1841..2392
                     /locus_tag="TVW25_001865"
     CDS             1841..2392
                     /locus_tag="TVW25_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1379458.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            2434..3180
                     /locus_tag="TVW25_001866"
     CDS             2434..3180
                     /locus_tag="TVW25_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1379459.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            3197..>4568
                     /locus_tag="TVW25_001867"
     CDS             3197..>4568
                     /locus_tag="TVW25_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1379460.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLI
                     DVFKEKN"
BASE COUNT         1864 a          556 c          951 g         1197 t
ORIGIN      
        1 aagttagttc ccaaacagga aaatggatta aaaaatagaa aatgaaatat ataaaacttt
       61 aaaagacaat tggagaaatg caaactctga ttgtcttttt tcatgtagaa aaaaggagga
      121 atttatgcaa acactggtga taagtgaaaa accgagtgtt gcaataagca tatcaaaggt
      181 gcttggagca acaaaaaaga aagacggata taatgaggga aatggatata gggtaagttg
      241 gtgtgttggt catttaattc agatggcaaa tccggatgct tatgatgaaa agtatgccaa
      301 gtgggatatg gctgatttac cgattattcc caaggactat aagtatgaag tagcaaaggc
      361 aaccaagaag caattcaaca tccttaaaaa gctgatgaat gataaagaaa ttgatacggt
      421 tataaatgct tgcgatgcag gtcgtgaggg agagagcatt tttagacttg tttataatca
      481 agtgaattgt aaaaagaaaa tgaaacgcct ttggatttca tctatggaag atagtgcgat
      541 taaagagggt tttgatcatc taaaagacgg aaagaaatat gacaatctct ttgaatcggc
      601 acaggcaaga gccattgcag attggttagt cggaatgaat attagtagac tttattcctg
      661 cttatataat caaaattact ctgtcggtag ggtgcagacg ccaactcttg ccatgattgt
      721 aaaacgagat gacgagatag caaactttaa aaaagaaaaa tattatactg tagagctatc
      781 tatggacggt tttatacttt ccacagacag aattgatgat aaggtagcag cagagcagct
      841 aatcaattta gttggtgata agattgaaat taccgatgtc attcaaaatg aaaagattac
      901 aaagccggat ttaccttttg acctgacaac acttcaaaga gagtgcaata aatattttgg
      961 atactcagct aagcagactc ttgattatgc tcaaagtctg tatgagaaga aacttattac
     1021 ctatccaaga acagacagta gatgccttac tgaagatatg attacaagta tgataaataa
     1081 catattggga caaaatgact ttgatacagg gcgtattaag gtcattttta attcaagcaa
     1141 ggtaacggat catcatgcta ttataccgac agtaagttca atgagtgaag atttattgag
     1201 tattccggag agtgaagcaa aagtgtatgg acttattttt aataagttac acgcaagtgt
     1261 gggctatcct ttaatcgaga atacaacaaa gattgtagtg acttttgacg gctttaaatt
     1321 tacaagttcc ggaaaagtaa ttaaggatga ggggtttact aagtatttaa aggaatataa
     1381 gacgaaaaag aatgaagata tagaacttcc aaatgtaaat ataggtgata gtcttaaaat
     1441 caaggataaa gaaatcaaag aaaaatatac gcaacctcca aaacatttta cggaaaacac
     1501 cttattaaaa agcatggaaa cagcaggaaa tgacgcttta aaaaaaggta ttgaggttga
     1561 aagaaagggt attggcacac ccgcaactcg tgcagggatt atagaaaatc taatttacaa
     1621 aggctttatt caaagagata agaaaaatct tgtagctaca cataaaggaa ttagtcttat
     1681 aacaattgtt gcagacaact ttaaatctgc tgaaacaact gcaaagtggg aaatggagtt
     1741 gtctgatatt tctcaaggga aatcttcaaa ggaagaattt ttaagaagag tagaagctga
     1801 gataagaaat gaattatccc gttataaaaa ggattagtct atgtttgata ctctaataaa
     1861 atttagtaaa gacagagaaa aattggattt ttatgccaca gataaaaggg caattcatga
     1921 acttttaaaa agagagcagt ttctatctcc tatttatgag ccggcttgtg gaatggggca
     1981 tatcggaaaa gttctggaag aatacggtta taaggtaaaa gctacagata tttgttatag
     2041 gggatatgga gaagaaagag aagttgattt ttttacagta acagaaaata tattggatat
     2101 agtaaccaat ccaccatatt tttgtgcaag tgagttttta aggcacgctc ttgaaatatc
     2161 aggacctaaa gtaaagatag caatgctatt tcggttggct tttttggaag gtcaatcaag
     2221 atatgaatta tttaggaaat atcctccaaa gagagtatat gtattttcca aaaggcttaa
     2281 ttgtgcaaaa aacggagaat ttgagaaata caaaagcagt gctattgcct ttgcctggtt
     2341 tatatgggag gtgggataca aaggtattac ggagttaagg tggattagat aaaaggatgg
     2401 aataaaacaa ctgaaaaaac gaaggaggat agtatggata agaatgaagt attacaatca
     2461 caggaaaatc agacaaagga agttatgcag gagattaaag aggaatatac caaaacagct
     2521 gactttttag aagaacatat aaatcagcag cttgtgattg ctaaggaaat gaaagaagag
     2581 atgcaaaata aggactttga tgtaaatatc aaagaattga aagcactcaa agaagaaatc
     2641 accggattaa aagctgaaat taaacgatta aacgaaatgg aaaatataac ttttggttca
     2701 ttgattataa gagatatcaa atctgtagga aataccctta tcaatttaca ggaaaaagcg
     2761 gtaggaagta ttaaacatct gtatgataat atgaaacatc agctttccta taaccttacc
     2821 aaagcacagg aaaaatttgt acagatgaaa ataggaattg taaaaggatt ggtaaattcc
     2881 atgcaggatt ttatcaagga tcaacaaaag aaactggata gttgcttagc aaaacttgat
     2941 aatctatcta aagaaattca aaaagatgaa gaaaaactgg aaaaaggcaa tctgaataaa
     3001 gagaaaaccc tgataaaaaa aagggaacaa agcatagagg aaaaagaaag tcaaaaggaa
     3061 aagatggaga aaaaaccgtc tgtgctaaaa aaattaaagg aaaatcagca aaaaatcaag
     3121 caggaagaaa agaataaaga tataaaggca cttaaaaaag ataagggaat ggaactataa
     3181 aaaagaggtg gtagttatga atgacctcat aaaaaactat gaaaatattc ctgatgagat
     3241 gaaaaaagag aagcgttggt gcctatataa aatcattcaa agagacggga agaacacgaa
     3301 acttccacta atgccaaata aagagccggc aaaatcaaat gataaagcta catggaatag
     3361 ctatgaggat tgtatcatgg cattaaaaca taatgttggc gaagggcttg gctttttctt
     3421 aggagatgga tacattggaa tagatattga taaagtaagt gatgacatta tggagtacaa
     3481 tacgaatcat catgtaagct ctatgacggc tgatttttta agagaagttt ccacctatgc
     3541 tgagatttct ccatcgaaaa caggactaca ttttattgga aaaggagagg tgccgggaga
     3601 aagaaaaaga tataaaaatc ttgaaattta tgataaggat aggtttttta cagttaccgg
     3661 taatgttata aaggatagag ataggagcaa aatagaaagt attgacagtg agctaaagcc
     3721 cttatatgaa aaatatatgc caaagacaaa taaaattagt gctgaaaata aaagaagtcc
     3781 aacggttact tcttacaatg gggatcagga catattagaa aagttatttg acaggggata
     3841 tttttcatat gcaggagaag atttaagaca aatttactat ggtaattatg aacgctattt
     3901 taacagccaa tcggaggctg atttttttat gctacaaagg ctgctttact atacaggaaa
     3961 tgtagaaatg gcaatatcat ttatggaaag tagcggactg aaaagagaaa aatggtataa
     4021 aagacgaggc aataccgatt atatccacta tattgcagat aaggcgataa gctctatcaa
     4081 tcaattttat gattgggaaa aagtatatac atcaaaggaa aaaatagaag aaaaaagata
     4141 tgaaaataag aagaaaaagg agggagatac agtgccaaga tatgaatttg atgaagtcaa
     4201 acagattctt gattttgcaa aagaagaatt taaagaaaat atagacaggt atgaaactta
     4261 tctcaaagtg atgggaaata actataaata tccgtacttt aaccagctta gcatatatac
     4321 ggtaaatgaa aatgcaactg cttgtgcaga atatgactat tggaaaagta taggaagaaa
     4381 tgtaaataga ggagaaaaag gaatacctgt tttagacatt gaaagagaga agataaagta
     4441 tatctttgat gcaagtcaga cagtaagttt aaatcacaac atttctgaag taaagttatg
     4501 ggaatatagc aataataagc atgtagctgc cttagatact cttatcgatg ttttcaaaga
     4561 aaaaaaca
//
LOCUS       DARYVE010000094         4444 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYVE010000094 DARYVE010000000
VERSION     DARYVE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4444
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            10..1176
                     /locus_tag="TVW25_001868"
     CDS             10..1176
                     /locus_tag="TVW25_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEL1379461.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWEIYVDNRLKAGVWSPDTYVERTNIFK
                     NHIGPKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDD
                     NIIKFIDIGDSEIKPINKRRSMQEFKAWDKIARKMLDDYDYAMVRITYLGLRRSEVAG
                     IKLGNITFNDKDCAVVKIDESRTRGRKDGGGLKTAYSERYVYLDFETSQLLKKAIDTS
                     IKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVNFTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYTHIKDEVSENVTAAFMGSIK"
     gene            1325..2101
                     /gene="recX"
                     /locus_tag="TVW25_001869"
     CDS             1325..2101
                     /gene="recX"
                     /locus_tag="TVW25_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1379462.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            2334..2867
                     /locus_tag="TVW25_001870"
     CDS             2334..2867
                     /locus_tag="TVW25_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1379463.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            3117..3428
                     /locus_tag="TVW25_001871"
     CDS             3117..3428
                     /locus_tag="TVW25_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1379464.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
BASE COUNT         1576 a          875 c          765 g         1228 t
ORIGIN      
        1 gatttaagaa tgaaatacaa caaaacaaaa tacccaaata tctttaccta cgatacaaag
       61 aaaggtaaac gctactacgt ccgtaggggt tattacttaa aaggtaaaaa gaaagaggct
      121 acaaaaagca acttaaaaac gctacaggaa gccagagctg cacttactga aattgagcaa
      181 aaaatagaaa acaatgattt tgcttataac aaaaatttga cagttgatca gtactgggaa
      241 atatacgttg ataatagatt aaaagctgga gtgtggtctc ctgacacata cgttgagcgc
      301 actaatatct ttaaaaatca catcggccca aagtttggca ataaaaaaat gaatgctata
      361 aaccgtatag aatacgaaaa ctacattaac aatctgctca ataccaactc aagaagtaca
      421 gtaaagcaca tatatgatgt ttttagtatt atgttaaatc atgctgtcaa aaataaaatg
      481 ctagacgata atatcatcaa atttattgac attggcgata gcgaaataaa acctatcaac
      541 aaacgtagat caatgcaaga gtttaaagct tgggataaaa ttgccagaaa aatgcttgat
      601 gattatgact acgcaatggt taggataaca tatcttggat tgcgtagaag cgaggtagct
      661 ggcataaaat tagggaatat aacttttaat gataaagatt gtgcagtcgt aaagatagac
      721 gaatcaagga ccagaggtag aaaagatggc ggaggcctaa agacagctta ttcggaacga
      781 tatgtgtatt tagatttcga gacatcacaa ctgctaaaaa aagccattga tacatctatc
      841 aaaatagccg tgtgcaacga tcgcatctta aacaaggctg atttcctatt tttaggagac
      901 gacgaaaaag taaagccatc ttttgtagga aaaccaatcg gtagccacta catctactgc
      961 ttatttaaaa aaatcaataa aaattgcgac gttaatttta ctccgcacat gatgaggcat
     1021 tttttcgcta cacagggcca aatagccggt gtcccaattg agcatatggc agcggcttta
     1081 ggtcattcaa ataattacat gactagccaa tacacccaca taaaagacga ggtaagtgaa
     1141 aatgtcacag cagcttttat gggcagtata aaataaaaat tccccgacat agtccccgac
     1201 aaaatattac tttttatgat ttttgttact ttttatgact aaacgaaaaa aactaaaatg
     1261 ctgtaatatc aacgttttaa aacaatttgc ttgtatataa attttaaaac attataatga
     1321 gggtatgaaa atcagtcaaa ttgaaaagaa aaagcattta tacctcatta agctagacaa
     1381 tggtgatagc ctaacggtca cagaagatac gattgtcaca tttatgctaa gtaagcacat
     1441 ggtcatagac agccaacaat gggaggacat caaaagcttc gcacaattct catatggtaa
     1501 aagcaaggcc ttaggtttta ttgccttcca acaaaggagc caaaagcaag tccaagatta
     1561 cctgctaaag catcagatta gtcctgatct cattccaagc attattgata gcctaaaaca
     1621 aggcaaatgg attgatgatc agcaatacgt tgacacctat atacgccaaa atagccttac
     1681 tggagacaag ggaccattac ttctcaagca aaagctaatg ctcaagggaa tagcctcaca
     1741 actcattgag cctgtcctag cacagactga tttttcctct atagcacaaa aggctgctga
     1801 aaaaatctac cagaaatatc aacacaaatt gccaagtaag gccttgaccg ataaaatcat
     1861 acaaggactt cttaacaagg gcttttccta tgaccttgcc aaaggcattg tcagtcaact
     1921 aagccttgag caggatagtc agcacatcga agacctgctt gatcaggaat tcgacaagct
     1981 attacgaaaa tacagtcgtc gctatgatgg ctatcagttg aagcaaaagc tttaccaagc
     2041 cctttaccgc aagggctatg acagtgatga tattaccact aagctaaatg actatttcta
     2101 attctaccaa ggctgctgca ccgatttgac gcaaaagctt ttagtcagca acaaagtagt
     2161 cctattatga tcctgtagct ttgataatgg tttagctagc tcctcaactg aacatcagat
     2221 ttctaaaaac ttctttaagc atttgtcaga tcatattgtc caaaacagtg atttattttc
     2281 tcaattatgg taaactatag aggataagtt taattgtaga aagttggtaa ggcatgaaat
     2341 tacctaaaga aggcgacttt attacaattc aaagttataa gcatgatggt agattgcacc
     2401 gaacctggcg cgatactatg gtactaaaaa caactgaaaa tgctctgatt ggagttaatg
     2461 atcacacact tgttactgaa agcgacggca ggcgatgggt gacacgagag cctgcgattg
     2521 tttattttca taaaaaatac tggttcaata ttatagcaat gattcgagat aatggtgttt
     2581 cctattattg caaccttgca agtccatacc tgatggacgc agaagcgctc aagtatattg
     2641 actatgatct tgatgtcaaa gtctttgcag atggtgaaaa gagattgctt gatgtagacg
     2701 aatatgaaat gcacaagcaa gaaatgcatt attcacctaa tctggatttt attttaaaag
     2761 agaatgtcaa gctattagtc gactggatca ataaagaaaa aggaccattt tcaaaagcct
     2821 atgtcagtat ttggtacaaa cgttatcttg aactgaagaa tcgttagtcg ttgtctagca
     2881 ctccaccgag ggtgctttat ttaatcgcta gtatagtatc acagctgtaa actggactgg
     2941 cacttgcaat ctatcagcat ttgttgtcaa attcatatca ttaaccacta tagcttggca
     3001 caagcacaga cagcctataa caccaagtag caatcagtat ttatcatcag ctgcctagct
     3061 agatcaggca ttcaaatgac ctcattataa caccataaca atagaaagga ttgacaatgg
     3121 catttcaagc aacaaaagga cgatacgcaa gctttggcgt tgcagtcagc cttccacctg
     3181 agctgattga taccttctgg gaaatcattg accattacct aaaaggggtg tttcccctca
     3241 atactgttct caccttcagg ctaattaaaa ataaaaaaaa cctttcttat gagtacattg
     3301 atcaacaagc tgggcttcgg attgtttttg actataacac accatttaac gccttttacc
     3361 ccaaaacgct ctatatcgta aaccagcaag gaattgaaac gattttattg cctcacgaga
     3421 tgtattgata agacctcgga catcagctat aaagtcctta ccattcagtt gtagctcatc
     3481 acatctgcta caagcaccaa catgagataa tcttgtgtct ttatcctagc tctgaatgct
     3541 gtatagatat tcagtcagcc agatacatag caataaacta agctcatgcc ggtagaaata
     3601 gtcctaacat gagcttgaca gttttttcat tctgtaaatc attgctaagc aaacacatca
     3661 cctaagccct atttcctatt ctgggaaatg gaaatcttga tagaacatcc caatagtccc
     3721 atcatattga gctatatcta tagggtctga cattttgata tgttatcatc tcattttacg
     3781 acaatcacta taggctttat gacaattggc atcattgtca taacgattaa attctatatg
     3841 accaaatggc tagtaggaag ctaattgctt tgtgttagcc tcacatagga tcttcacata
     3901 ccccgtaatc ttaaaagtag ttttaactgc acaaaactta tagaacctaa aaatcaacaa
     3961 acacacttta aagtacaaaa actttgccct ccctcaaaaa gctctataat ctctgtagtc
     4021 ggtaagccca ctgtggaaat tatagttttt ttaattgtac aaaaacaagc ccatatgact
     4081 tatcatgaaa tgcaatcaaa ccatcattag aaagactcat aggaacacct taagcattac
     4141 tcagcattta aaaaacaata tccaaccgtt gactgttcta aaagctcacc cccacatcgt
     4201 tatcaatcct aagcttgatt attcagttct cttatgccct cactacaaag gaaacatgag
     4261 caaacaagac ttccaaaaag cctctaaaat ccctatcttc gattgccaaa gctttccaac
     4321 actgcttcaa ctcaaaaaac actgctttca gtggaaagcc agttctaaag tgagccttgc
     4381 tcaaactcct tttggtttta acatcacaaa aaagagcacc aatctggtcc tctttagacg
     4441 ttag
//
LOCUS       DARYVE010000095         4343 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYVE010000095 DARYVE010000000
VERSION     DARYVE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4343
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            104..286
                     /locus_tag="TVW25_001872"
     CDS             104..286
                     /locus_tag="TVW25_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1379465.1"
                     /translation="MLIYDEFKQAVDNGYITGDTVAIVRKNGQIFDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            484..873
                     /locus_tag="TVW25_001873"
     CDS             484..873
                     /locus_tag="TVW25_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1379466.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            870..2081
                     /locus_tag="TVW25_001874"
     CDS             870..2081
                     /locus_tag="TVW25_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1379467.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2094..3440
                     /gene="asnS"
                     /locus_tag="TVW25_001875"
     CDS             2094..3440
                     /gene="asnS"
                     /locus_tag="TVW25_001875"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1379468.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            3740..>4343
                     /locus_tag="TVW25_001876"
     CDS             3740..>4343
                     /locus_tag="TVW25_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1379469.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEAGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPK"
BASE COUNT         1270 a          905 c         1089 g         1079 t
ORIGIN      
        1 tcacacacat gtattcacac attggcatat ccgttataac ggacttgtta aaattagtcc
       61 attaaactag actttttacg aataataagg taggaggtaa tttatgctaa tatacgacga
      121 gtttaagcag gcagttgata acggatatat cacaggagac acagtagcga ttgtgcgcaa
      181 aaacggacag atttttgatt atgtgttgcc gcatgaggaa gtaaggaacg gggaggttgt
      241 gacagacgaa aaagtggaag aggtgatgag agaattagac aaataaaaaa gacctcgtcc
      301 agaagtcggg gaattgtcgg ggacaacgtt tgtaaatgtt tctattccaa cataaaacat
      361 tttttgatat aataggaagg atcatatgca aaggagctga aattggacaa gcacaaaagg
      421 ctcaaaacag ttttatatca atgtgccagc ttggtcgtac tgctttgtct tggagtgatg
      481 agcatgtttt atcttgctgt tcatgatcaa tttgacaaga aatcaaggtt agccgagata
      541 gcaaaatcaa gagctggtgt catctcaatt gatcatattg attgctatca tggcactcag
      601 agctacctca gtctttttgg aaaaaacaag gcaggcaata ccatcatcgt cacaatagag
      661 gagcaatcag agcagctctt gcttagtcgc cctagcaatg gcattagtgc taaggaagca
      721 caggaaattg cctaccatgc cggagcaagg actattgaag cagtgacatt tgggattgaa
      781 aaccacaaga ggatttggga ggtggctgct caaaacggct actatctgat tgatttcaaa
      841 accgcaaaag tgatcaaaaa ggaggtttta tgaccaagct atcaaggcgc gtgttagcaa
      901 tggaagaaag cgtcacccta gcagcaggtg ctagagcaaa ggcactaaag gctcagggac
      961 gcgatatttt aagcctaact ctgggagagc cagattttat aacaccgcag catatccaag
     1021 aaaaggccat tgaggccatc accactggta aggcaagctt ttacactgtt gcttcggggt
     1081 tgccagagct caaggacgcc attgctgatt acatggcacg atcctatggt tatattccta
     1141 ccagacagga gattgtagtg gggacaggcg ccaaatacgt tttgtatgcc tttttcatgg
     1201 ctgttttaaa tcctggtgat caggtgttga ttccgactcc ttattgggtt tcttatgctg
     1261 atcagattaa aatggtagac ggggtaccgg tctttgtaca gggcttggag gaaaatcaat
     1321 ttaaggtcac agtagagcag ctagaggctg ccagaactga tcaaacaaag gttgttttga
     1381 tcaattctcc gtccaatcca actggcatga tttacagccg acaggagctt gaagccattg
     1441 gcaattgggc tgttcagcat gatattctga tcctggcaga tgatatctat ggtgcattgg
     1501 tctacaatgg caatcaattt actccaatat cagccttatc agaggctatt cgtagacaga
     1561 ccattactgt aaatggcgtt gccaagagct atgcgatgac aggctggcgt ttgggctttg
     1621 cggtcggaga cactgatatt atcgctgcta tgggtaagat tatcgggcaa accacctcta
     1681 atgtgacaac agcgtcccaa tatgcagcga ttgaggcctt tggcggtgac caaacgtcag
     1741 ttgaggagat gagacaggcc tttgaagagc gcctcaatac catttatccc ctgctcaatc
     1801 aagttcctgg ctttgaggct attaagcccc aaggagcctt ttatttcttt cccaatgtca
     1861 aaaaagctat ggagatgaag ggctttaccg atgtgacagc ctttactgat gcgatcctag
     1921 aagaggtagg actggctgtt gtcagcggag ctggctttgg tgctccagaa aatatcaggc
     1981 taagctatgc cactgatttg gcaaccctaa aagaagctat cagacgactc aatcagttca
     2041 tgacaactga cagcagccat gacaacaaag agaatgaata gaaaagagac attatgacca
     2101 aaaaatacgt ttccattatc gatgttaaag accatgtagg acaagaagtg acagttggtg
     2161 cttgggtcgc caacaagtca ggcaaaggga aaatagcctt tttgcaattg cgtgatggct
     2221 cagccttttt ccaggcagtt gcctttaagc caaacctgat ccaagccttt ggtgaggaag
     2281 caggagcagc taagtttgac acgattaggc atctcagcca agaaacctct gtcttagtaa
     2341 agggcattgt caaagaggac gctagatcaa aatttggcta tgagctagac attacggacc
     2401 tagaggttat tggggattcc aaggattatc caattactcc aaaggagcat gggacagact
     2461 ttctcatgga tcaccgtcac ctttggctgc gctctcgcag gcaggcagca atcatgcaaa
     2521 tccgtaatgc catcatctat gcttcctatg agttttttga tcaaaatggc tttatcaagt
     2581 ttgatagccc gattttatca ggcaatgctg ctgagaacac aacagagcta tttgagacag
     2641 attattttgg caatccagcc tttctcagcc aatcaggtca gctatacctt gaagctggta
     2701 tgatggcgct tggtcgcgtc tttgactttg gtccggtatt tcgtgccgaa aaatcaaaaa
     2761 cgcgccgcca tctgacagag ttttggatga tggacgcaga ataccccttc ttatcccatg
     2821 aggaatcctt agacctacag gaagcctatg ttaaggcgat gattcagggt gtgcttgatc
     2881 gtgctccaca ggcattggag cttctagagc gtgacacaga gctgctgaaa agatacattg
     2941 cagagccctt caagcgtgtc tcctacgacg atgcgatcag cctgcttcag gagcacagca
     3001 cagatgacga tgccgactat gagccaattc agcatggcga tgactttggc tcaccgcatg
     3061 aaacctggat ttccaattat tttggggtcc caacctttgt catcaactac ccagctagct
     3121 ttaaggcctt ttacatgaag ccggttcccg gcaatgaaga gcgcgtgcta tgtgcggacc
     3181 tgctagcacc agagggctac ggtgagatta tcggaggctc ggttcgtgag gataactatg
     3241 acaaattgtt ggcgaaaatc aaggctgaag gcctaaatcc tgaggattat gacttttacc
     3301 ttgaccttcg caaatatggc tcagtgccgc atgctggttt tggacttgga ctagagcgca
     3361 tggtgacctt tgttgcaggt accaagcaca ttcgtgaggc tattccattt ccacgcatgc
     3421 ttcatcgctt aaaaccataa tgaaccctat cagcgtccgc cattgggcgc ttttttgctg
     3481 cgctgagcag tacttagagc tcaagcctcc cagttagact tggcagagct gtggctcttt
     3541 gcttgagcta ttgtaggcaa aggtatcact ggatctgaaa acaacaaaat cagacaagtg
     3601 atatcaaaat taaaaaaaaa aaaaacgaaa cctaggagga tcggtgagct tattagtttg
     3661 gcactaatca tcattatgct ataattgtct tcacaaataa tttagaaata gctcatattt
     3721 ctatcattaa aggagagaga tgatgaatcg taaaaagcat accaaactca ttcgtcacta
     3781 cagtatctgc tcagcagtgg ctgtcctagc agcagttagc ttgggaacag gtcaggacgt
     3841 acaggcttcg gaacccaatc catatccaga tgtgaggcgt ttccttgatg agaagtacga
     3901 tggagatgtg gataaattat ctaaacaact tcaaggttat tttggtagtt taagagagta
     3961 tatagagttt gaacttaaaa atggcaaaca aggtcctgct ggccctcaag gcccaaaggg
     4021 tgataaagga gaccccggag agccaggtcc tcaaggtcca gtgggccccg ctggtccaaa
     4081 gggtgatcgt ggtttagacg gacgacgtgg cccagcaggt cagcaagggg aagccggccc
     4141 agttggtcct cagggtcctc aaggcgagca agggccaaaa ggcgaccgtg gcgaacaagg
     4201 accaaagggt gaacgcggtg agcaaggacc aaagggtgaa cgcggtgagc aagggccaaa
     4261 aggcgaccgt ggcgaacaag gaccaaaggg tgaacgcggt gagcaaggac caaagggtga
     4321 acgcggtgag caagggccaa aag
//
LOCUS       DARYVE010000096         4069 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYVE010000096 DARYVE010000000
VERSION     DARYVE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            295..2097
                     /locus_tag="TVW25_001877"
     CDS             295..2097
                     /locus_tag="TVW25_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1379470.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TVW25_001878"
     CDS             2075..2674
                     /locus_tag="TVW25_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1379471.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TVW25_001879"
     CDS             2782..3708
                     /locus_tag="TVW25_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1379472.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..>4069
                     /locus_tag="TVW25_001880"
     CDS             3701..>4069
                     /locus_tag="TVW25_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1379473.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILGL"
BASE COUNT         1256 a          754 c          786 g         1273 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggactt
//
LOCUS       DARYVE010000097         3521 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYVE010000097 DARYVE010000000
VERSION     DARYVE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3521
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            1..1690
                     /locus_tag="TVW25_001881"
                     /pseudo
     CDS             1..1690
                     /locus_tag="TVW25_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
     gene            complement(1711..3324)
                     /locus_tag="TVW25_001882"
                     /pseudo
     CDS             complement(1711..3324)
                     /locus_tag="TVW25_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1234 a          679 c          471 g         1137 t
ORIGIN      
        1 gaattttaga tccaattgat tatctacaaa ggcttaatgg taaaattgga tattacacaa
       61 aaaattactc tcctctagga gattgtatgt atctaacaca agaaaatact gaaaaaattg
      121 ataatatcag acagatcata gaagattgga acaacaatca attactcaca gagtacgaat
      181 atttttacct tttaaatgct ttgatagaag ctattcctta tgttagtaat attactggaa
      241 cctatggcgc ttttctcaag cattgggaca accgagcgtt gcattcctta acattagcag
      301 aagagactat ttttgataat tatcgtccta acaaagcgtt taatgaaaat gctaatgaat
      361 tagtcaaaaa aataaaagca gatattgttt acattgatac cccctacaat gctcgacaat
      421 acgcatcaaa ttatcattta ctcgaaaaca tcgcccgaca tcaaaagcca attttaaaag
      481 ggattactaa aatttttgat tggaaaactc ttaaaagtga ttattcaaca aaaacaaagg
      541 ctttaaaagc aatggaagat ttaattgcta atattaatgc tagtcatatc attctaagtt
      601 acaataccga gggtattata tccgaagaag atttaacact tttacttcaa cgatattcgt
      661 tcaataatca aattgatgtg aaacggattc cttaccgaaa atatcaatct aagaaaaaat
      721 ctcagaacaa agacttatac gaacttcttt tttatattca aagaaagccg ataaataatc
      781 gcttcaaatc acaaactaaa aaaaaggcag ccatcatcag tcaaaaaaag tatataaaaa
      841 gcccattaaa ttatatcggt ggaaaatatc gactgctaaa tcaaatcatt ccaatttttc
      901 cccgacatat caatacattt gttgatatgt ttagtggggg gcaaacgttg gtatcaatgt
      961 tcctgctaaa aaacacatct ttaatgatat gaactatcgc attaatgaca tgtttcgata
     1021 ttttcaatca catgacccac ttgagatact tgaacaaatt gagcatcgaa tttcagaata
     1081 tcaactcagc aagaccaatg aacaaggctt tttaacattc cgaaaacatt ataatactca
     1141 tccaaatcca ctagacttat acgtactatc gtcttatagc tataactatc aatttcgctt
     1201 taataactca atggaattca ataacccatt cggcagaaat agaagtcatt ttagtgaaaa
     1261 tatgaaatcc aatctactca attttgtagc tcgactacac cgtttagatg ccactttctc
     1321 tgatcaattt ttctcagatt ttgatatttc tacattatca atagatgatt ttgtttatct
     1381 tgatcccccc tacctcataa cgactggcag ctataatgat ggaaatcgtg gcttcacaaa
     1441 ctggggcgaa aaacaagaaa ttgaaatgta tcaattaata agagacctta acaagaaaca
     1501 aattaaggtt gcacttagta atgttcttgt tcataaagga aagcacaatg atttacttga
     1561 gcaatttgtt caagatgaaa gtctatatct caccacttta aattacaatt ataaaaatgc
     1621 ttcatacaac acaagaaaag aagatagcat tgaagtattg attaccaatt ataaaccaaa
     1681 tccaaaataa taaaagcata gttgaattag ctatgctttt acaaattcaa tttctttatt
     1741 ttgaaaataa gatggtaaat cggaaatatg cagttgtcct ttaagaacca aatctgctcc
     1801 caaaagcaat tgctctacat tgagggctgc tcccttaatt tgtgtttcat tagaggtata
     1861 atcaagctgc tcttgaaatt ttccaatgaa tttacttgac acccacataa aataaaactc
     1921 ttcttgtgga atcgtatctg gaaaagcttc ccaccacttt atcggattac gattttcatc
     1981 tcgtcgctta ttatcctcaa tataccgaat catttcatca gcctgattga tagatttaga
     2041 ataacctttt ccataagcct ttgtatctac aatcacacca aaacgatctt gatagagtaa
     2101 accatctggc tttctgccac cacctaaaag cttagaatgc aatctatata catttctaaa
     2161 taattccatt gtaacaattt caaaatctcg atttcgctta ccatcgtaag caatatcaag
     2221 caattcaata tatttcattg gtaaattagt ctcttttaaa aattttgcct tacgcttttc
     2281 tgcctgctca tcctttaatt cttgtgtaat ttctagttca ggaatagaaa aatcgttgat
     2341 cttatccttc aaagaaactc tattgctaga aatatctatc ctcaaaccaa aataattcaa
     2401 tccttgaata tctgataaga taatctccag ttcatcgtaa aaacccttag cccttagttt
     2461 atctaataga atagccaaag aattagtttc ttggagaaac ttgacgatat aagctctccg
     2521 agtacgaaca tactcgcgat tattgccatg agttgcaaaa aattcccaca tcacaaattt
     2581 ttcaagcttg ctatgcttag aatccccctg agcttgtcgt aaagcatgaa gaccacgacc
     2641 attaatttta taaccttgaa atccatcttt ttcaccatta gtaaaggtac gcttaatcgt
     2701 ttgtgaatca accaaaccaa cattttttag ccaattacaa ataccgcgtg catatttatc
     2761 acttgttcct tctatatcag ctttaataag ttttttctct gatttagtgg cagatcctaa
     2821 ccaatcaaac ataatatctt cattatagga agtaaagcct ttttcaccac gaaaaccaag
     2881 ctgctcacct aaataatatt tagtacaata agtaccgcta tcagccaata aagataagat
     2941 ttgtgtagct ggcgggtatg acaacagtgc ctttcttaaa atagcagttt cttcttccga
     3001 attaattatt gccctagaaa aatgcaaccc cttcgaagta attgaaaaca tatccgtttc
     3061 tctatctacc gacacaaaat tcaggctaac agcccatctt aaaaaaccat ctgatgtcca
     3121 attatccgtc caagttttac ctgtattttt tgcctgttga ggtacgatgc tgatttgaat
     3181 caaagaatct gccattgcat ctgaacgctt tcggggagat ttgttattct tatcctttga
     3241 tgttccaact aattctaaat atgaaaatga ttgaatccca ttaatcagtt tgtttctgag
     3301 tgattctcgt ggtacttcaa agaaatctgt acccaaccat aagttcttat tttcataaga
     3361 gctccttaat cttatactta ttatctttat tatagcatat aattaatcct tccagttagc
     3421 attatcacaa agcaacaaca tttcttattt aatggggcta ctatgtagct attttaatac
     3481 atgtttttac ctcacgaaaa cacccccact tgtcaagtct g
//
LOCUS       DARYVE010000098         3310 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYVE010000098 DARYVE010000000
VERSION     DARYVE010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3310
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            88..2274
                     /locus_tag="TVW25_001883"
     CDS             88..2274
                     /locus_tag="TVW25_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1379474.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2386..3105)
                     /locus_tag="TVW25_001884"
     CDS             complement(2386..3105)
                     /locus_tag="TVW25_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1379475.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
BASE COUNT         1005 a          713 c          598 g          994 t
ORIGIN      
        1 ttagctccat atttttggta taatttaatc tgagatttta tttggagatt atatctttta
       61 ggaaaaaatg ataaggaagt tcttactgtg aagaatttta aaacatttat cacaagcttt
      121 atcaatacaa gattaggctt tgtgctaacg cttctcttct gcttttggat aaaaacccta
      181 tgggcttacc atgctgactt ttcactagat ttgggaaatg cctatcaggt ctttctaaca
      241 attattaacc caatccctct agctttgtta ctattgggat ttacccttta tatcaagaat
      301 actagggcct tttatatcag ctcttggatc gtctatatta tccttaacct cttgttaata
      361 tcaaattcta tttattaccg agagttttca gatttcatta cggttagtgc tatgctagcc
      421 agtagtaagg tttctgctgg tttaggagac tctgctttaa accttttgcg catttgggat
      481 attgtttacg tccttgattt catcattctg attagtttat cagtaactaa gaccatcaaa
      541 aaagacccgc gtccttttaa caagcgggct tcctttgctg ttacagcact gtcttgcttg
      601 ctcttatctg ttaatctgtt tcttgcagag attgaccgcc cggagcttct gactagagga
      661 ttttcaaata cctatatcgt tagagcgctt ggattgcctg cttttaccat ttacagcgga
      721 aaccagacct atcaagcaca aaaagagcgt aacggagcaa ccgctgaaga attagtcgat
      781 gttaagcaat atgtcaagaa ccactacgcc gcacctgatc ctcaatattt tggaatcggt
      841 aagggaaaaa atgtcattgt gatccacttg gaaagcttcc aacaatttct tattgattac
      901 aagctcaagg atgacgacaa ggactatgag gtcacacctt ttattaattc cctctaccac
      961 tccaatgcca cactagcctt ctctaacttt ttccatcagg tcaaggctgg aaaaacgtct
     1021 gatgcagaga ccatgatgga aaattcatta tttggcttaa acagtggttc ttttatggta
     1081 aattatggcg gcgaaaacac acaattcgcc acaccatcaa tcctagcaca aaatggcggc
     1141 tatactagtg ccgtctttca tgggaatgta ggaaccttct ggaatcgcaa taatgcttat
     1201 aagcaatggg gctatcatta cttttttgat tcaagctatt tttcaaaaca gactgataaa
     1261 aactctttcc agtatggcct aaatgacaaa tacatgttta gagattctat caagtacctt
     1321 gaacagcttc aacaaccctt ctacactaag tttattaccg tcagcaacca ctacccttac
     1381 accagcctta gaggcgaaag cagtgaagag ggctttccac tagccaaaac cgatgatgaa
     1441 accatcaatg gttactttgc tacagctaac tatctggatt cagccttgaa atcatttttt
     1501 gattatctca aggcgacagg actttatgac aattctatct ttgttctata tggtgaccac
     1561 tatggtattt ctaattccag aaatgtcagc ttggcagaat tactaggtaa agaccctgaa
     1621 acttggtccg aatatgacaa tgcaatgctc cagcgtgtac catatatgat ccatattcca
     1681 ggctatacca atggcgggat caaagaaacc tttggcggag aaattgattc cttaccaacc
     1741 ttactgcata tcttgggcat tgataccagc aagatggttc aactaggaca ggatctcttg
     1801 tcgccacaaa atagtcaaat ggtagcacaa agaacctctg gaacttatat cacgccagac
     1861 tacactagct atagcggtcg cctttacaac actcaaacag gcttggaaat tacaaaccct
     1921 gatgagatga caatggctaa ggtcaaagaa atacgagcag ccgttgctca gcagctagca
     1981 gctagtgacg ctatccaaac aggagaccta ctacgctttg ataccgataa tggtctgaaa
     2041 cctgttgacc caacaacctt catttatacc aagcagctaa aacaactcaa agagatatca
     2101 gagaaattag gatcacattc aaccagcatt tatagtaaaa atggcaacaa atcaactcaa
     2161 aagctcttta aagcaccttc ttatctggag ttaaatccta aagaagccga aaaacctgaa
     2221 tctacttcgt cttctgaccc taaagaagaa tccgttaagg aacaaagtca gtagtggatg
     2281 tctaaagcaa gcctcactag gatcgctctc gtagaagact aaaagcaagc taaaagcctt
     2341 cattgagcgt tacaacttaa tgagggcttt ttagttctga cacttttatt gaggaatggc
     2401 ctcaaagtat tctggatctg gtgtcggttc aggtgttggc acaggatcta gcttaggctc
     2461 aggcttcggt tctggtgttg gcacaggatc tggcttaggt tcgggtgtcg gtgctgggct
     2521 attttcttgc gtcacaatat aacccacata acagtaatca tcaacctttt cttctggagt
     2581 gtaagtaaag cttaccccct taaccgtagt cttagtgacg atatcattga gatgacgtac
     2641 cacatcaact gcactaacag ctgttgtcgc accaccagct accaacaagg caatcaacac
     2701 atagctaccg cttttcctat ttttgtaaat aagatagcct gaaacactta gtaagcctag
     2761 ccctactgcc aaaccaacca gaccatctgc tgcaccaccc gttttaggca agaccttagc
     2821 gttagcctta ggggtagaca tcattccttt tggagatgct gtcactccac agcttttgtc
     2881 gtaaacaaga acgtaatgca atttatcttg gataggtact tcatttggag tgcctttttg
     2941 aatgcctgct ttttgttcat ttgtcagatt agaataggct gtataggtca aatctaccgt
     3001 taccgtatca gcattagtgt tggcattgac attagctgct agcaaagata gacctaacat
     3061 cgttgtagct cccatgtatt gaaacgcttt agaaaaacgt ggcattataa ctattctcct
     3121 taatgttttg tagaataaaa ccaataacta aaaaggcatc tcctatcata tcaatcttat
     3181 gattattata ggtaaatgtg atttttgtaa gcactatcta aaaatttcaa atacactcat
     3241 atcaatagat attgaccaaa tctcagcagc tttaagcata tcataacaat aaatcacctt
     3301 attgacacaa
//
LOCUS       DARYVE010000099         3256 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYVE010000099 DARYVE010000000
VERSION     DARYVE010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3256
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..1556)
                     /locus_tag="TVW25_001885"
     CDS             complement(<1..1556)
                     /locus_tag="TVW25_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379476.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLRS"
     gene            complement(1559..2311)
                     /locus_tag="TVW25_001886"
     CDS             complement(1559..2311)
                     /locus_tag="TVW25_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379477.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2642..3121
                     /locus_tag="TVW25_001887"
     CDS             2642..3121
                     /locus_tag="TVW25_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1379478.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          610 g         1005 t
ORIGIN      
        1 gatcggaggt attccttttt agtttcgata tgacctataa cagtatcacc atcactaatg
       61 attcccttat catcactaat actcctaaga tcagccttag ttaaatcagc ataggccgaa
      121 atgctggccc ttccgccagt atgattaatg ctttgaatgc tatcttgaat gtcctttagt
      181 gtttccatat ctttgaccac aagaactgca ccattataag tgttagctgc ctctgggaag
      241 gttactgatg ttaaattttt gacattggta tatgatttgc ccaaaatatc cagctgtcgt
      301 aattgactat cccctctttg cttaaagaag gcagtctgat tgtcctttaa ttcaggcaat
      361 tgattgccca aggcgcggaa atcatcttga gtgactaagt agacatagcc tgtagtgact
      421 ggactaggat ttagcaagga ttctttggtt actacaatgg tttctttttg ggatacttca
      481 aaagaaacca tgctactata atagactaga aaatccgagg caggcttatt ggtcttttca
      541 acaataagtc tgttaaaaac ctctttttga ttgtcaatct ctgaattatc aaaattaata
      601 tgagtatttt taggaaaaag ctggttagac attgcctcgc tattagcata aagcgcagtt
      661 gttgttgcta ttgcaacaaa ggccataaca gctaagaggg taatatttgc caagcctaca
      721 gcattttgct tcattctaaa aatcatctga gaggtgctga caaaatgctc tggctggtaa
      781 aaataagcct tgttttgacg acgacgcttt aagtgccaag tcataaagga aatgtaaaag
      841 agataggtcc cgataataac gataataact gctataaaaa accgatataa agtgtctaat
      901 gctgtcagct ttgtcgatga taaggagatg taatagccaa tactaagcaa tatgatggat
      961 aaggctgcta gtaataaatt accctttggc tctttttcac cctgttcttt atgacgaaag
     1021 agcattaagg gagaggtctt tctgatttta atcaagccaa caacctctaa taaaccaaag
     1081 atagcagcaa agattaaagt ggtgtaaata aaagcaacgg gattgatttg taattctaaa
     1141 tggactgctc cgaccagatt agcgaaaatc aaataaaaga cgtgtgaaaa aatagctgat
     1201 aggatacttc ctacgactac tgtccctaag tacataaaaa caagctcgat cgttgagact
     1261 aaaccaacct gctttttatt cattcccaaa atattgtaca gaccaaattc tcgacttctt
     1321 tgctttagta aaaaattata gctataaatc tccataatag tggcaaagat gattaaaaca
     1381 aagattgcta gtcctaatag cataaaccca tgtctcatcg attctgatac ggggctcatc
     1441 atgataatca agacaataca attgagcata tataaaacag tgcttgccag taaaaaagga
     1501 gctgtgacgg ataaggactt tcgtagatta ttccaagcta gtttgagata aaacatcttt
     1561 attcacctcc taaaagaccg gccatggcaa tcgagatgtc tttgctaaat tctaaattcg
     1621 ttttatttcc acgatagatt tggtggaaaa tacggccgtc cttgataaac agtactcgct
     1681 tagcatggct agcagcattg gcagagtgtg ttaccatcaa gagtgtctga ccgtctaggt
     1741 taatggcctc aaaaagattg agaatatcct ctgaattgcg gtaatcaagt gctgctgttg
     1801 gttcgtcagc taataataat tgcggattgg tgattaagct tcttgcaata gcaacccttt
     1861 gcttttgacc accagaaatt tcaaatggac gtttatctaa aagcgtttca atgcgcagct
     1921 taggggcaat gatgttgagc cgtctttcca tttctttaaa tggcttacgg tttaaaacaa
     1981 ggggtaaaaa gatattatct ctgatcgata gggtgtctag gaggttaaaa tcctgaaaaa
     2041 caaagcctag gttttgaagt cggaaattag ctaggtcacc ctccttaatt tttgtaatgt
     2101 cagtgccatt caataaaaca gatcccttgg ttggtttttc cagagttgcc agaatattta
     2161 atagggttgt tttccctgag cctgactctc ccatgatggc aataaactca cccttgtcaa
     2221 ccttaaaatc aacatcttgt aaggctctag tttcttcctt tgaaaagcgt gtccgaaaaa
     2281 ccttctctaa atgattaatt tctaataaca tatgaaactc ctttgtgtct attatactct
     2341 tttagcttta aatatagcca ctatcgtgac gtatttagct agtgatgcat ttagtgcctt
     2401 ttgtcagcct taaccactcc ttctttcatg aagcagccca gctctcaaca agaatcgtct
     2461 tagctgactg aacctattgc tctaaactct tttttcttta cagcttatag tttaccctaa
     2521 ttaatagtct ggttagctta caagatttga tgggtgactt acagatttgt aagttttata
     2581 acatcatttt tcttatcatt ttgatataat gaaaggagaa ttctatttag gagaagcgtc
     2641 aatggctaag aaaatcaaaa aaacgctagg gactgtcgga aagctgtttt ccattatccc
     2701 tgataccact gaaattatag gaaaaacgat agataacacc cgtcccatta tcgaaaagca
     2761 tatggaacaa aagcatgaaa aggaaatgca gctaacgctt ttagatgatg tgattaattt
     2821 acctgttgat aaagcgcaaa agcatctgga acagctaggt tttgttgtcg cactattgcc
     2881 ggtcaagcct agtaaaaaat ggatacatgc tagcttaaat gaggttgttt ccatgtcacc
     2941 taagcctgga aagcataagc tgggaagctt agtaaagctt tattatgtta ctgtagatgt
     3001 ccttgagaaa agtcaggcta ttttagatca agagacccta aaggctgtcg aacgaaatca
     3061 aaaaatcgct gataccatcg aagctgttaa gcaaatcaag cttcctttta aaaagagata
     3121 aggctatact gtaaaaaata agctgatacc gttaggatca gtttattttt tatgttgtga
     3181 ctttaagtct atctcgctta gcaggtgcca aacaaataaa ccacccgtta tgtaccgacc
     3241 ttcaatggtt aaagtt
//
LOCUS       DARYVE010000100         3151 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYVE010000100 DARYVE010000000
VERSION     DARYVE010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3151
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            134..204
                     /locus_tag="TVW25_001888"
     tRNA            134..204
                     /locus_tag="TVW25_001888"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:166..168,aa:Cys,seq:gca)
     gene            complement(311..1378)
                     /locus_tag="TVW25_001889"
     CDS             complement(311..1378)
                     /locus_tag="TVW25_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1379479.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGASN
                     SLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAHQL
                     DKLKEKNNQAIKDIFGNLTDF"
     gene            complement(1505..1780)
                     /locus_tag="TVW25_001890"
     CDS             complement(1505..1780)
                     /locus_tag="TVW25_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1379480.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(1770..1988)
                     /locus_tag="TVW25_001891"
     CDS             complement(1770..1988)
                     /locus_tag="TVW25_001891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1379481.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(2004..2525)
                     /locus_tag="TVW25_001892"
                     /pseudo
     CDS             complement(2004..2525)
                     /locus_tag="TVW25_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            2914..3120
                     /locus_tag="TVW25_001893"
     CDS             2914..3120
                     /locus_tag="TVW25_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1379482.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
BASE COUNT          922 a          580 c          547 g         1102 t
ORIGIN      
        1 attattaaaa atgattttct gatttaaact ctaaaaaata acataaaccg aaaaaaggag
       61 cagcctgcta aaaaatagct gctattttta tcttgacgaa tgctatcaac tagggtaaaa
      121 tagttcttgt tatggcggta tagccaagtg gtaaggcacg gctctgcaaa agcttgatcg
      181 tcggttcaaa tccgtctacc gccttttata tacaaacgaa tccttgatta acctcgtaaa
      241 aacgttgtta aatcaaggtt tttatttttt gtggcaggat aaaaaaagag aaaaaaagaa
      301 ataaagtcgg tcaaaagtcg gtcaaatttc caaaaatatc ttttatggcc tgattgttct
      361 tttcttttag cttatctagc tgatgggcat ataccttaag cgtaatgttc aaattctcat
      421 gcccaagcaa ctgagatatg gatattaggt caacaccctt taagattaaa aaagatgcgt
      481 aagtatgacg tagagagtga ttgcgtacag gacgaccaac aattttttta accaatctat
      541 tgcagagtga attagaagct ccgtagagca ccctatttag cttattttca ttataataat
      601 tttctttaaa tgctctaagc aattttatag tttgctgatc aatgggaatt tgtctttttg
      661 attgctcgtt ttttgtttcc ttaaattctt gagtttttga gtaatcaaac gatttattaa
      721 tatctataaa tcccttctca aagtctatat cgctccaagt tatcccggtc gcttcggcga
      781 atcgtagtcc agtcactgct atgatgtata aagtaaaata ggaaacatac tggtatttct
      841 cactcgttac tttgattaga tttagatatt catcttcttc aaggaaatca aattcttttg
      901 ctctagcttc tttttgagat tttacaatcg caccttcggc aaaatttgtt ttgataagcc
      961 catctctaac tgctacatta acagctcctt ttatttgata gtggagtttt tcgagtgttt
     1021 cttgggcata ttttttggca aattcgttga ttgttttttg gtaaaaggta tgcgttacat
     1081 tattaagctt aatatcacca aaatattttt tgatgtgctt aagattttta gtgtaagttt
     1141 cccaagtttt atcgacaaca tgcggacgtt tgtagatttt agcccattcc ttgcaaaaat
     1201 cataaagtga tatatcatca atatctttat ttagctcagc ctcgacttta atcgcagctg
     1261 cagaagccaa tgcttttgtc ttaaaaccac ctttggattt ttcccttttg ttcccctgac
     1321 tatctgtgta gtaaatacga taagaccact tgtcgccgcg ttttctaaat tttgccattg
     1381 ttaattacct catttttatg ttaaaatggg tacagtaaag agacctactg cgaagcaggt
     1441 tttttactat acaggatttg cctcacgctc agactcgcca aagtttgaga gcgtggggct
     1501 ttttttaacg tttgatttta tagactgagc ttcgatgctc tattttaaaa acttcgatga
     1561 caacttcgtc atcaataatc tcagctaaaa tacgatagtt tcctaaacga taacgccact
     1621 ctcctgtacg attagcttgt aaagcttttc cgtatctcct tgggttatct gtgccatcaa
     1681 ggttagtcat tatccactga tagagttgtt tagcagtaga tctatctaat tttttgagtt
     1741 gttttttggc ttttttagta aacaatactt tataacgcaa aacctagctc cttcgctaca
     1801 tcttccatgc taaatcgtgt cccatcgtcc tcagccttag cttttctcaa ttcgtacaaa
     1861 tctttagcat cttcaatgat ttccaaaaac tggtcaactg ttagattgga ggtgtcaatg
     1921 ttattttctt tgatgtaatc tgcgatataa gcatcgtctt tttcaaggtt taatgtcatt
     1981 gcaatcatag tatttttctc cttctatatt tctactggtg taaagctgcc gacgacatca
     2041 tagattttga tgtaagtatc ttctgctggc gggtagtcga taaagatatc attgtatttt
     2101 ttattgagag atactaatct aagcccgtct tcctctgtgt atactttttt aaaataggtc
     2161 tgtccgttat gcacaactat acatagctga ccggcatatg ctgacatgcc ccgatctaca
     2221 atatagagca tatctccttg ctcgtacttt ggtagcatac tatcgccccg cactccaatt
     2281 gcatagtcgt agtgaggtgg ttcttcgtca gtgtagacag tatatgtgtc atattcatct
     2341 gcttcaaatc cacgaccaaa gccacttgcg gctgccgcgt aagttacgcc ttgaaccgaa
     2401 aataattctt catgcgtaga aacaacttta ttttgttctt ccaattgctc cttggcaaag
     2461 tcaaggactt tttcttgtct aggttgttct agttggttgt agatggacac tatttcagat
     2521 gtattttttg gggcatctag cagagacgaa aacacctcgg gtctgatacc taaagctgag
     2581 caaattttta tggcattctc gacgttagca ttcattattc ctcgctctaa tatcgagcga
     2641 accgttgagt aaggcatgtt gttttcttct gcaaaagatt ttacagagct ataacgagaa
     2701 agtataagat gttttagatt ttcttcattc atggctgcct ctctttctga tttcattata
     2761 acacacgatt tttcgtttgt ctaacaaaaa aacactaaga aatacgaatt ttagtattga
     2821 caaacacgaa aaaaagtatt aaacttgtat caagctcaga tgagcttaac tttaaaacca
     2881 aaaacacgaa aaatcgtgtt agaaaggagt tatatgttaa atattgataa agtgcgaaaa
     2941 gaaaaaggcg tagcaatagt agacatggct gattttcttg gcgtaagagc tcaaacagta
     3001 agcgataaat tgcgcgggac ttacgatttt aaatttactg aggctttggc gttgcaacaa
     3061 aaatttttcc cggagtacga tttagaatat ctttttaaca aagcagtaga cactgcttaa
     3121 ctttaaaacc aaaaacacga aaaatcgtgt t
//
LOCUS       DARYVE010000101         3099 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYVE010000101 DARYVE010000000
VERSION     DARYVE010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3099
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVW25_001894"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVW25_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1379483.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1290)
                     /locus_tag="TVW25_001895"
     CDS             complement(664..1290)
                     /locus_tag="TVW25_001895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1379484.1"
                     /translation="MSITAILLLSPNKDLMCDACQRHFCRITQPTCSNCYQYRHEGAC
                     QDCIAWKRQGYQVDHQSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKA
                     YTLVPVPVSKQRYDERGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNR
                     YRLKKGAALPPKILLIDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TVW25_001896"
     CDS             complement(1473..1658)
                     /locus_tag="TVW25_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1379485.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TVW25_001897"
     CDS             complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TVW25_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1379486.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTINIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNW
                     EFHGSGENEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
     gene            complement(2835..>3099)
                     /gene="spek"
                     /locus_tag="TVW25_001898"
     CDS             complement(2835..>3099)
                     /gene="spek"
                     /locus_tag="TVW25_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL1379487.1"
                     /translation="KITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDI
                     HYKDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVYLNEEFSKN"
BASE COUNT          926 a          635 c          470 g         1068 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta ttctcttttt ttatagtatc tctattataa atttctctta aggtagtagg
     2401 ggataatgtt ttatctacat cccaccttgg agagtatata tccttaatat taatagtccc
     2461 ctccgcagaa accatcctaa cagaaaatac caccaatgac aatactacta taaaaaaagt
     2521 agttgacata ttaaccaaac gacaattctg acgtaaaaaa attctcattt atcttattat
     2581 tctccttaat aaatcaatat agctgtgaaa ctatgttttt tgaacttgaa cctcaaaatg
     2641 cttaaatcgg aagtacttga gcagacttct taaaagataa taaactgatt ctataacgca
     2701 cagaaattaa tctgagcggt tttatcatat tcctcggttg accgatagtg atgcctagaa
     2761 gtctactaaa accgtctaat tcatcaaaat ctatttaaat agactaaaaa ttaaattaaa
     2821 atagcattcg accgttaatt tttagaaaat tcttcgttta agtaaacatc aaagtgacta
     2881 actttactca tatcaatcgt ttcattatct gtatagtcgg ggtaagtaaa taaattggtg
     2941 tgtctaatgc caccgtcttt ataatgaata tcccaaaacc cttttttata caaagaatcg
     3001 tactcataca attttatttt gctgtctccc atcaaacttt tcctaagtct aacatcaatc
     3061 tcctgaagag ttacaatatt atttttaaag gtaatctta
//
LOCUS       DARYVE010000102         3075 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYVE010000102 DARYVE010000000
VERSION     DARYVE010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3075
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            18..98
                     /locus_tag="TVW25_001899"
     tRNA            18..98
                     /locus_tag="TVW25_001899"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TVW25_001900"
     tRNA            105..175
                     /locus_tag="TVW25_001900"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TVW25_001901"
     tRNA            187..259
                     /locus_tag="TVW25_001901"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TVW25_001902"
     tRNA            268..339
                     /locus_tag="TVW25_001902"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TVW25_001903"
     tRNA            358..441
                     /locus_tag="TVW25_001903"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(785..1915)
                     /locus_tag="TVW25_001904"
     CDS             complement(785..1915)
                     /locus_tag="TVW25_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1379488.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            2480..>3075
                     /locus_tag="TVW25_001905"
     CDS             2480..>3075
                     /locus_tag="TVW25_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1379489.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRG"
BASE COUNT          988 a          573 c          676 g          838 t
ORIGIN      
        1 gtaatttaat atgttttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat acttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg
      421 gttcgacccc ggccgccggt atagtttaaa aatattgaaa aaacaaggtt tgtaaacctt
      481 gtttttttgt tttatgactt gatgtcagag gatcagattg gtcctctcta gatgttaaag
      541 gtaatgagaa tcttggcttc aaagctccta aatccaaagc attgcgcttg atgtctttga
      601 tcacctgtta gtggcgtgca gcttagcgtt tgaatttgga ataaggttgc tccaaggcat
      661 gtgtgatgtg agctttggat actaggactt ttagccaatt ctttgtgggt gagctttttc
      721 tttacgtttg gttttgatta atgtcgcaat atcagttatc atgtgttctc tggttaatga
      781 cgctttagca aatatcgtat tgtcttagca tcttgtttga gaaataaagc agactaatta
      841 agataagcga acccaaggca agtgttggga tggttacggt ataaaaagca ctgaaaactt
      901 caccaagatg ctcatcagga atctcagttc gtaaaatagg tttttgggta acatgcgtta
      961 ttccgagaaa tagacaggaa agaaaccaaa gaagcaacaa accaaaacgg ttggggacta
     1021 atgctgtaag gccaataccg gtgcccaaaa gggtagttgc tagccaaaaa gcttttccta
     1081 cacttaactt ttgcaagaca aggttagcaa caaaggttgt tcctaccagg gttccgatag
     1141 cacttacaga tactaagagg ccataaaaag ctgaattccc tacctctctt gctattaata
     1201 actgatagac atttaagctg gcaaaaagga aattagcgat agcacctccc aatgtgatgg
     1261 ctaacaccac tttattgtgc cagataaagc gcaagccact taaaaagtct gttcgttcat
     1321 ttgtttgttc aattatttct ttaaatgcta ttcttctaaa aaataggatt gaacctaaga
     1381 aggtaacgat attaatgaaa agcaaaggaa tgtagctgat cacagaaagc aaaaagccac
     1441 tgatggcagt aaaaacataa tctgttccat tataagccac tgacatatac atttctgctt
     1501 tagctagatc tttagtagga atgagtttag gtacaagagc atcttgaaca gtataggtat
     1561 tcaacccaac catagaagcc agaaaaacac aactaaaaat aatggttaag ctaagacttg
     1621 cgtgtatctc tcttaaggac attcctaaaa taatacctaa gacagccaat aattgggccc
     1681 actccagaat cactagcagg ttcttcttag ggtacgaatc aatctttttt ccaaagataa
     1741 aggagaaggt gtttggaata aaaatgagaa agttcaataa tccaacatac caagtactat
     1801 tagtggtttc tagtacatac caggacagca ctagggtata aatcgagtca ccgcaattgc
     1861 taatcagtcg ccccagaaat aaccggcaaa aatcattata tttccttaat atcatattgt
     1921 atcctttgat aaagagttta aacatctttt atattatagt atcagatgat aaaaaatcac
     1981 tgaatgatag ctgtgtttga tgtttgcaac attttaaaat atctttgcaa aaatcatacc
     2041 tagacacata caatcccaca taagttttaa aagcattcaa ttgcctttta agatctttat
     2101 gagtcatgtt tgtaaagata tcctcttgca acagatctct taatctctaa ttgtatccaa
     2161 taagaagcag ctttgtcaat acggaagccg aatagtcttt ttgcctttcc ttgtcagctg
     2221 ggcaatcatg agggctttgt gctttgatct tttgcatcta taaaagggtg aatctattga
     2281 tgaggtgtta tcggtagtgg ggcctactga tgtcaataac tgacgtcaga taattacctc
     2341 tttaattaga aaaaaaaaaa aacgaaacta cggagagaac ctaataactg gctatttctt
     2401 gctataagcc agcgtgttaa aatcttcttt gggagaaaat ttagaaaaaa ataatatttc
     2461 tatcactaag gagagaaaga tgacaactaa agaaaaacaa acaaaactaa tgcgcaggta
     2521 tggcattttc tcggtagtcg ttgccctaac agctctagca ggtctaggag cagctaatga
     2581 agttaaggca actgctaaaa aatctttaaa tgagttacct aatccagtag aaattattca
     2641 atataattca acaagaacta ctgatagaga agctagaaag tatcttaatc aattatatga
     2701 gtttttgaaa ccttatttag gaagtttaga agaagaagct caaaaaggag ggccacaagg
     2761 acctgtggga cctgctggtc ctagaggtga acgcggagaa ccaggaccta aaggagaccg
     2821 aggtcctgag ggccaaagag gtgagcaagg cccagcgggg cctattggac cccaagggcc
     2881 tcgtggtgac aagggtgaaa ctggagaaat tggacctagg ggagaacaag gtccgaccgg
     2941 tcctactggt aagccaggag agcgtggccc taagggtgac agaggcgaac gcggcgaaaa
     3001 aggcgagcaa ggccagcgtg gcgaaaaagg cgagcaaggc caacgtggcg aaaaaggtga
     3061 acaaggccaa cgcgg
//
LOCUS       DARYVE010000103         2719 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYVE010000103 DARYVE010000000
VERSION     DARYVE010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..>2719
                     /locus_tag="TVW25_001906"
     CDS             <1..>2719
                     /locus_tag="TVW25_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1379490.1"
                     /translation="KLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQ
                     SDESKFDLTDVQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHP
                     MLRTKFTKDGKQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQ
                     VAGVALAKFSDEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYM
                     QNGIGESINDADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWET
                     IKDIAASYRSTPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTN
                     ILLVEHEAVDDSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVF
                     ACNIDYPLETEFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGM
                     LEDMMDSLYELIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFL
                     RNVKLNPDRVAIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQ
                     LYAIFGILFTGAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKII
                     DLDVAMANVAKLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYN
                     VNAEDTILMVSAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIW
                     DSVPILFDMIVTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGA
                     TEASIWSNHLNVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVG
                     VAKCYHGDEELTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVK"
BASE COUNT         1008 a          308 c          578 g          825 t
ORIGIN      
        1 aaattaaaga aaacggggat aaaaatttcg tttgcaaaac ttatggaaga accgaatttg
       61 tccaagtggt atgaacttat tgataaatcc agagtgaaaa gtgataagaa tatagagtca
      121 tcaattatcc aaagtgatga aagtaagttt gatttaacag atgtccagta ctcctattta
      181 atcggaagag aagatgatca gattttaggt ggcgtgggtt gccatgcata tcttgaaata
      241 gatggagaaa atattgatga ggataagtta aaagaggctt ggaataagct tcaatacaga
      301 catcccatgc ttagaacaaa atttacgaaa gacgggaagc aggaaatatt atacaaaccg
      361 tacagtgaag aaatagaagt ttttgattta tctgatcttg atgaagaaac gctgcatcta
      421 aaattagtag aaattagaga acaaaaatct cataggaaat taaatgtaaa tcaaggtcag
      481 gttgcaggag tagcactagc aaaattttca gatgagaagt caaggatatt ttttgacgta
      541 gatttgcttg tatccgatgt aatgagcatg agtattatga ttaaagaatt agctgaactt
      601 tattcaggag tagaacttga taatttgaat gagtatacgt ttaaggatta tatgcaaaac
      661 ggaattggcg aatcaatcaa tgatgcagat aaggagtttt gggaacaaaa aataaattcc
      721 tttgaaatag aaagaccgaa cttaccatta aggaaacagc cggaacaaat taaagaaacg
      781 aagtttacaa gaagaaagag aattattaaa aaaagtgaat gggaaaccat aaaagatata
      841 gcagcatcgt atcgaagtac accatctatg gttcttctaa ctgcctatgc tcttgttctt
      901 gaaagatggt gtaatcagga taaatttttt atcaatatac cgctatttaa tagagattta
      961 gaaaatgaaa atctaaaaga aatggttgct gattttacaa atattttatt ggtagagcat
     1021 gaggctgtag atgattcaaa ttttttagat aatttaaaga gaataaataa gacattcttg
     1081 gaaaatgtat ctcacagtga gtataacgga gtgcaggttc aaagagatat atcaaaaaaa
     1141 caaggtacaa gtgtgtatat agcacctgtg gtttttgcgt gtaatataga ttatccattg
     1201 gaaactgaat tttcaagaaa aaatttaggg aaagtatctt atatgatttc tcaaacacca
     1261 ggagtttggc ttgattttca aacatatatt gtagatggag atttaattct ttgctgggat
     1321 agcgtggatg aactttttcc aacaggaatg ttagaagaca tgatggattc tttatatgaa
     1381 ttgatcatat ctttaacaca gaaggaagaa tgggaaaaga aagtagatgt tttacctgaa
     1441 aagcaaaagt ctattagaat gcaggatgtt gagggaattt taccacttca atatcctagc
     1501 gaaacgttat atgacggatt tctcagaaat gtaaaactca atccagatag agttgcgatt
     1561 atagattctg aaacgaagga agagataaca tatcataaac tttatgaaat ctctttaaaa
     1621 gttgcggatt gtttaggtaa aaatggtgtt aaaaagggag attatgtagg aataacactt
     1681 ccaagaggta gcagacaact ttatgctatt tttgggattt tatttaccgg tgcagcatat
     1741 gtatcaattg gtattgctca gccaaatgat agaagaacta aaatttatga tcaaatcgga
     1801 ataaagtgca ttataagtga tgaaaagaca gtgatagatt gtaaattaaa taaaaatgaa
     1861 gttaaaatta ttgatttgga tgtagctatg gcaaatgtgg ctaaattaaa gcaacctgtt
     1921 gaaattagcc cttatgatag tgcgtatatt attatgacgt ctggaacaac aggtgttcct
     1981 aagggtgttg agattatgca tacaagtgcc gttaatactt gcattgattt aaatgaaaaa
     2041 tacaatgtaa atgctgaaga tacaatactg atggtgtcgg caatagactt tgatttgtcg
     2101 gtttatgata tttttggaat acttcatgct ggaggaacgg ttattacaac aagtgaagat
     2161 aattatagaa atcctgatga atggttaaat ttagtcgatg aatataaggt tacaatatgg
     2221 gattctgtgc cgattttgtt tgatatgatt gttactatgg ctgaaggtaa aaatagaaac
     2281 ttacctttta gaattgtgat gctttcaggg gattggattg ctataaattt accagaaaga
     2341 ttctataata ttagtgaaaa tataaattct attgttgtcg ctatgggtgg agccacagaa
     2401 gcatctattt ggtcaaacca tttgaatgta ccaagaaaaa taccgaaaga ttggatttcc
     2461 attccatatg gtagaccttt gaaaaatcaa gtgtatagag ttgtggatga atttggtagg
     2521 atctgcccta attatgttaa aggtgaactt cttatcggtg gagttggtgt tgctaaatgt
     2581 tatcatggtg acgaagaatt aacgaataaa aagtacttcg aacaagatgg gatgaggtgg
     2641 tatagaactg gagataatgg tagaacatgg aatgatggga ttattgagtt tcttggaaga
     2701 aaagatactc aggtaaaag
//
LOCUS       DARYVE010000104         2568 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYVE010000104 DARYVE010000000
VERSION     DARYVE010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            373..831
                     /locus_tag="TVW25_001907"
     CDS             373..831
                     /locus_tag="TVW25_001907"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1379491.1"
                     /translation="MKETVVLAKKEYILENEIYTPIVKESPFERQGGTYRLEKMEDGA
                     EVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLMDHLIDIQEQVE
                     DFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQIIWV"
     gene            717..>2568
                     /locus_tag="TVW25_001908"
     CDS             717..>2568
                     /locus_tag="TVW25_001908"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1379492.1"
                     /translation="MENDHRNAGSGLSEIHRTEEELGYDTNKNGYGTDHLGIDEYRKE
                     NIQKIEQNHVENEEKEVERTSFSFAQNVGVQGRFELPMQQEEIGAVLIHGGNEDNLHL
                     KVLAEYSKEKSMEELADFLQKTFQGGNGYELNGNKVCAWYEMDGIHLSNDVSSRENPM
                     QILPWKDAAIRIGELIDYGKYSTNVEVAEAFSFERAELSEKLWFLKGDLSDEVKNQFL
                     PILNEKQRNGYPEKTEYLTKKLEDKEFRVNLKEEYIEFFKAYKENSNVLRFHNHDLDD
                     ISKRLDDLELPRKEFTSTLIELPAIQGFITEDEIDRYLSSGSNVSGGKERIYNFFREA
                     HTTEERANFLKDEYGTGGQTHALSRARGSSEWHDAKGIKLEKENCKDIILKWNQVVKK
                     IDNLIENGKYIQEDVYTEQESIKTEEEYFDEDTYTEQNSKENEQDWQREQEILLIQDE
                     REVSYEEAEEIYERQAEIEHNAFATGVENNISSTQSNKDYWIVEFNEGSNLIEKNYAG
                     EVVTKKLLDEIKVLDEKIRVHNKTVGEDEYGEMTDEWVGYSKFYFDHIVDGKVEEHFR
                     MDIGDGNEVNQRDFQYLYEQIEPEKENKEYGMDSIDSVIKDILEKESMTVV"
BASE COUNT         1062 a          281 c          583 g          642 t
ORIGIN      
        1 atgaaacttt aaaggaaaat aagaaagtac aaattcttca ttttttggaa gaatctgcaa
       61 aagtatcggt atatgagaga atgggagttg cattttccgg tgatatagaa aaattagaga
      121 tgctttcaaa tgtttcaagt atgcaggata ttgacagatt acttttcttt acttcaaaca
      181 atgtaaaaag aatacttatg gatataagta gagaaatttc aaaagtggaa gaaagagaaa
      241 aaatttcaga aattcaaaaa agggagcaga caaatagtat tgcggagcgt tatactaatg
      301 ttacagatga aattaacgga aataccgaaa ttatagaaaa tgaaaaagaa agaaatgaag
      361 gaggtttgga agatgaaaga aaccgtagta ttggcgaaga aggagtacat cctagaaaac
      421 gagatttata caccgatcgt aaaagagagt ccattcgaga gacagggagg gacttacaga
      481 ttggagaaaa tggaggatgg agcggaagta ttagttccga atatgaaaat gccggagaaa
      541 ataaacgcaa gcaaactgaa ccgatttggc aaggagagac tgaaatatct caaagaggag
      601 aaacaagagg aatatcagat tatgctgatg gaagaaactt taatggatca tttgatagat
      661 attcaggaac aagtggagga tttcctgaat atagaagagc cgaggatgaa agaagcttgg
      721 aaaatgacca cagaaatgca ggatcaggac tttctgaaat acacaggact gaagaagaac
      781 ttggatatga cactaacaaa aatggctatg gaacagatca tttgggtata gatgagtatc
      841 gtaaagaaaa tatacagaag atagaacaaa atcatgtaga aaatgaggaa aaagaagtcg
      901 agaggacttc tttttctttt gctcaaaatg taggagttca aggaagattt gaattaccaa
      961 tgcagcaaga agagattggt gctgttttaa ttcatggagg aaatgaggat aatttacatt
     1021 taaaggtttt agccgaatat tctaaagaaa aaagcatgga agaattagct gattttcttc
     1081 aaaaaacttt tcaaggagga aatggatatg aactaaatgg aaataaggtt tgtgcttggt
     1141 atgaaatgga cgggatacat ttatccaatg atgtttcctc aagagaaaat cctatgcaga
     1201 ttttaccatg gaaagatgca gcaatacgca taggagaatt gattgattat ggaaaataca
     1261 gtacaaatgt ggaggtagca gaagcctttt cttttgaaag agcagaactt tctgaaaagc
     1321 tgtggttttt aaaaggagat ctaagtgatg aggtaaaaaa tcagtttttg ccaattctaa
     1381 atgaaaaaca aagaaacgga tatcctgaaa aaacagagta tcttacaaaa aaattggaag
     1441 ataaagagtt tagagtgaac ttaaaagagg agtatataga gttttttaag gcgtataagg
     1501 agaactcgaa tgttttaaga tttcataatc atgatttaga tgatatatca aaacgattag
     1561 atgatttgga actgccaaga aaagaattta cctcaacact tatagaatta ccagcaatac
     1621 agggatttat cacagaagat gaaattgata gatatttaag cagcggtagc aatgtatccg
     1681 gcggaaaaga aagaatatat aactttttta gggaagccca tactaccgaa gaacgagcaa
     1741 attttttaaa agacgagtac ggaacaggag gacagactca tgctttatca agggcaagag
     1801 gaagtagtga gtggcacgat gctaagggga taaaacttga aaaagaaaat tgtaaggata
     1861 ttattttgaa atggaatcag gttgtaaaaa aaatagataa ccttattgaa aatggaaaat
     1921 atattcaaga agatgtatat acagagcaag aaagcataaa aactgaggaa gaatattttg
     1981 atgaagatac ctatacggaa caaaactcta aagaaaatga acaagattgg caaagagaac
     2041 aggaaatttt gctgattcaa gatgaaagag aagtatctta tgaagaggcg gaggaaatat
     2101 atgaaaggca agcagaaata gaacataatg cctttgcaac cggtgtagag aataacatat
     2161 cgtcaactca aagtaacaag gattattgga ttgtagaatt taatgaaggc tcaaatctga
     2221 tagaaaaaaa ttatgccgga gaagttgtta cgaaaaaatt gcttgatgaa atcaaggtgc
     2281 ttgacgaaaa aattagagtt cataataaga ctgtcggtga agatgaatac ggagaaatga
     2341 cagatgaatg ggtaggttat tctaaattct attttgacca tattgtagac gggaaagtag
     2401 aagaacactt cagaatggat atcggggatg gaaatgaggt aaaccaaaga gattttcaat
     2461 atctttatga gcagattgaa ccggaaaaag aaaataaaga atacgggatg gatagtatag
     2521 atagtgtcat aaaagatatt ttagaaaaag aatctatgac tgtggtat
//
LOCUS       DARYVE010000105         2473 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYVE010000105 DARYVE010000000
VERSION     DARYVE010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2473
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            51..1004
                     /locus_tag="TVW25_001909"
     CDS             51..1004
                     /locus_tag="TVW25_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1379493.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1064..2263
                     /locus_tag="TVW25_001910"
     CDS             1064..2263
                     /locus_tag="TVW25_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1379494.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          746 t
ORIGIN      
        1 tggctagtgg tattcttttc atttcagcct tattttgata tgatagacgt atgaattttg
       61 aaaagattga acaagcctat gagcttatat tagaaaatag ccagctgatt gaaaatgatt
      121 taaaaacgca tatctatgat gctattgttg agcagaattc tttttatctg ggagcccaag
      181 gagcaagccc tcaggttgct aaaaatattg agacgttgaa ggccttgcag ttaaccaagg
      241 aggagtggcg ccaggcttat cagtttgttt tgatcaaggc tgggaaaaca gagccattac
      301 aggccaacca ccaatttacc ccagacgcga tcggctttat catgctttat attttggaga
      361 ccttgagctc acaagagtca cttgatgtgc ttgagattgg cagtggaaca ggtaatttag
      421 ctcaaactat tttaaaccac tcacataaga gcattgatta tttaggcatt gagcttgatg
      481 atttactaat tgatctatca gctagtatcg ctgaaatcat ggggtcatca gcccagttta
      541 ttcaagagga tgctatcaga cctcagctgt taaaagaaag tgatctcatc attagcgatt
      601 tgccagttgg tttttatcct aacgacgata ttgctagcag gtatcaggtg gctagctcag
      661 atgagcatac ctatgcccat catttactga tggagcaagc cttaaagtac ctgaaaaaag
      721 atggctttgc tattttctta gcaccggtaa atcttttgag cagcccacaa agtcacctct
      781 taaaacaatg gctgaagggc tatgctcagg ttgtggcctt gattactttg cctgaggctg
      841 tgtttggaaa tccagctaat gcaaaatcga ttattgttct ttgtaagcaa tcgaatcgct
      901 ttgcagaaac ctttgtttac cccattaggg atttgaaatc tgttgataat gttcgtgatt
      961 ttatggaaaa cttcaaaaat tggaaacggg ataatgttat ttaagagaat tttttgatat
     1021 aatagaaaag cattgcagaa aacgatttca agagaggtaa aacatgtcaa agacaattgc
     1081 aattaatgca ggaagctcca gcttaaaatg gcagctatat caaatgccag aggaaaaggt
     1141 attagcacag ggaattatcg aacgtatcgg tctgacagac tcaatctcta ctgttaaata
     1201 cgatggcaaa aaagaagagc atattcttga tattccagat catacagagg ctgttaagcg
     1261 cttgttgaat gatttgattc attttggcat tattggtacg tatgacgaga tcacaggtgt
     1321 tgggcaccgt attgttgcag gtggtgaata cttcaaggaa tctgtggttg ttgatgataa
     1381 ggttgttgag caggttgagg agttagcagc cttggcaccc ttgcacaatc cgggggcagc
     1441 agcaggtatt cgtgcctttc gtaagatttt gccggacatt acgagtgttt gtgtgtttga
     1501 tacttcgttt cataccacaa tgcaaaagca tacctacctt tatccaattc ctcaaaaata
     1561 ttatacagat tataaggttc gcaagtacgg ggcgcatggg actagccata aatatgttgc
     1621 tgaggaagca gcaaaaatgc tgggtcgccc tctagacgaa ttaaagctca ttacagccca
     1681 tgttggtaat ggtgtgtcta tcacagccaa ttatcatggt cagtcagtgg atacctctat
     1741 gggctttaca ccgcttgctg gtccgatgat ggggacacgc tctggtgata ttgatcctgc
     1801 tattattcct tatttgattg ctcaggatcc tgagctaaag gacgcagcag atgtggtcaa
     1861 tatgcttaac aagcaatctg gattaggtgg tgtgtctggt atttccagtg atatgcgtga
     1921 tattgaggct ggcttgcagg ctaacaatcc agatgccgtc ttagcttaca atatctttat
     1981 cgatcgtatc aagaaattta tcggacaata ctttgcggta ttaaatggtg cagatgcctt
     2041 ggtctttacc gcaggtatgg gtgagaatgc tcccttgatg cgccaagatg tcgtcaatgg
     2101 cttgtcatgg tttggtatgg aaattgatcc agagaaaaat gtgtttggtt atcgtggtga
     2161 tatttcaaca gcagcttcaa aggtgaaggt gcttgtcatc tcaactgatg aagagctgtg
     2221 tattgcgcgt gacgttgaac gcttgaaaca gactatatca taatctgata atatactctt
     2281 agctcagctg atcagtttta aagagtccaa aaaatacttt taattggtac cgacctccaa
     2341 aagttagact taaaggttta acgattggag gtcggtatta ttatatagcc aaatattctc
     2401 aagacaaaga cagccaaaaa atgagacggt cgtaaccgtc tcaaaaaagt ttaatttaat
     2461 taaaaacatt cat
//
LOCUS       DARYVE010000106         2420 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYVE010000106 DARYVE010000000
VERSION     DARYVE010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2420
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..530
                     /locus_tag="TVW25_001911"
     CDS             <1..530
                     /locus_tag="TVW25_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEL1379495.1"
                     /translation="LNIHELDEVIDFCFKQGLLRIQLSSIFSIHNRLLVSDEKYAAHY
                     NKLIEKFSCLGVQFLTSPFCHPWSLAIKHGIEYHSPLYCPAQKTEFEIDMYGDVYPCP
                     FLHDKIHLMGNLISDDFETIWYSGVEQLNRRAWSSNDSCKNCKLFNDCGGGCYAMAFV
                     SQLEYDKRCILHANQ"
     gene            517..777
                     /locus_tag="TVW25_001912"
     CDS             517..777
                     /locus_tag="TVW25_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1379496.1"
                     /translation="MQISKNWFIRFEPNFQTTQNTILFNKVSGELFEVTEVYYDCINS
                     LRIGVDFQALLMEKYAVNAGDVIDVEDTILKNLISLGVILNE"
     gene            770..1669
                     /locus_tag="TVW25_001913"
     CDS             770..1669
                     /locus_tag="TVW25_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379497.1"
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKST
                     LIKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHL
                     NNLSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEP
                     TNGLDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSF
                     SEIFGENNTWMKYRIGIPKFEKAIFDQLFPFLAYQVEDERLVVEVTDSQTKHHIFEHF
                     EIIFFEEVEKSIEELLYEVITDD"
     gene            1659..2399
                     /locus_tag="TVW25_001914"
     CDS             1659..2399
                     /locus_tag="TVW25_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379498.1"
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFED
                     TQSQFLLLCLLFTWYFTSHSLTHPIFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQ
                     LLVDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVF
                     NRTSSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAY
                     GMIYWSVGTLLFSRALTMAKKRGSLFHV"
BASE COUNT          742 a          349 c          480 g          849 t
ORIGIN      
        1 cgttaaatat ccatgagctt gatgaggtca tagatttttg ttttaaacaa ggattgttac
       61 gtatccaatt atcttctatt ttttctattc ataatagatt attagtatct gatgaaaaat
      121 atgctgcaca ttataataaa ttgatagaga aatttagttg tttaggtgtt caatttttaa
      181 catcaccttt ttgtcaccca tggtctcttg caataaagca tggaattgaa tatcattccc
      241 cactttactg tccagctcaa aaaacggaat ttgagattga tatgtatgga gatgtctatc
      301 cttgtccatt cttacacgat aaaattcact taatgggaaa tttaatttct gatgattttg
      361 aaactatttg gtactctgga gtagaacagt taaatagaag ggcttggtca agtaatgata
      421 gttgtaaaaa ttgtaaatta tttaatgatt gcggtggagg gtgctatgcc atggcatttg
      481 tttcacagct agaatatgat aagaggtgta tattacatgc aaatcagtaa aaattggttt
      541 attagatttg aacctaattt tcaaacgaca caaaatacga tattatttaa taaagtaagc
      601 ggagagctgt ttgaggtaac agaagtttac tatgattgta tcaattctct gagaattggt
      661 gtcgattttc aagctcttct gatggaaaag tatgctgtca acgcagggga cgtgattgac
      721 gtagaagata cgattttaaa aaatctaata tcgctaggag taattcttaa tgagtgacat
      781 cactatacgc catgtcaaga aaagctttca tcatcaggta gtcttagatg tgcctagttt
      841 tgatgtaaag cgtggagaaa ttgttgctat cgttggtgca aatggtgcag gtaaatcaac
      901 tttgatcaaa atgatctctg gtttaatgct gcaagacaca ggatctgttt tggtttatca
      961 tcataaaaat acttcagcag ctattcatcg tgatgtgaaa tttgtcttag aaagtggtag
     1021 gggctattac gagtatctga ctgcaaatca aaatattgat tactttttac atttgaataa
     1081 cctgtcacgt agccaagtca aagaagaatt ggcagagttg tgccaaaaat tggcttttaa
     1141 tccctatact gatcggttgg tttctgaatt atcccaaggc acaagacaaa aattgtcttt
     1201 gattattgct cttctttgtc agcccaaggt tctgtgctta gatgagccaa caaatggtct
     1261 agatgtggtt gcaaaaaagc aatttgcaac cttgttgctt gagcttagtc aaaaaaagca
     1321 aacgattatc ctgatgacga ctcatgatat cttttttgta aaagagctat cagcaagaat
     1381 ttgtgtcatg agtaaaggga agatcaaaaa acaggggagt ttttcagaaa ttttcggaga
     1441 aaacaatacg tggatgaaat atagaatcgg tatccctaag tttgagaagg ctatttttga
     1501 tcagttattt cctttcttag cttatcaggt agaagatgag agattagtcg tcgaagtgac
     1561 agatagtcag acaaaacatc atatctttga gcattttgag attatatttt ttgaagaagt
     1621 tgaaaaaagc atcgaagagc tattatatga ggttattact gatgattaaa gaaatacaaa
     1681 gggagttgaa aagacaattg caggagatga tgcaattcaa attcaattta ttttttgcaa
     1741 actttggtat tttgatcatg gtgtcatctt atcttcacta ttttgaagat acgcagagtc
     1801 agttcttgtt attatgtcta ttattcactt ggtattttac gagtcatagc ctcacacatc
     1861 caatcttttt tattgaagat gacctttatg atagaacgtt gatcagtgtt attcaaagca
     1921 gcaagagtgt ttttcatgtc ctcatgctta aaattattgt tcaactattg gtggatttag
     1981 ttaaggcaat acctattgtt attatgttat cactccttaa taatattgac tttccagaaa
     2041 gtagcttgag ggtgatggga agctttgttg cctgtttttt gacagtcatt agtacatacg
     2101 gtcttggctt ttgcttatcc agtctctgtt ttgtgtttaa tcgtacctcc agtgttactg
     2161 cgttaatttc ttatttcatg ctatacttta ccggcatact aacgccatta gatggctcac
     2221 ttggtcttat tggaaaaatg ttcccttatt atgctttgag aaatgctatt atgtctcctt
     2281 catatcagag cgtatgttgg attgtggctt acggtatgat atattggtcg gtcggtacgt
     2341 tattgttttc tagggcattg acaatggcta aaaaaagagg gagtcttttt catgtttagt
     2401 gaaatgaaac gatatatgac
//
LOCUS       DARYVE010000107         2356 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYVE010000107 DARYVE010000000
VERSION     DARYVE010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2356
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            11..1432
                     /locus_tag="TVW25_001915"
     CDS             11..1432
                     /locus_tag="TVW25_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL1379499.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIGRLRVLLDE
                     KNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEITEILSTLV
                     DRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKGVGEFVLNG
                     VADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAIFLFGNKEA
                     EDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISAIEQANKQC
                     DGDIDMSVKNIVQAVKILNKEEF"
     gene            1433..1930
                     /locus_tag="TVW25_001916"
     CDS             1433..1930
                     /locus_tag="TVW25_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL1379500.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(1954..>2356)
                     /locus_tag="TVW25_001917"
     CDS             complement(1954..>2356)
                     /locus_tag="TVW25_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379501.1"
                     /translation="SKYIIKAADERQNLQDKIKAIDKEMQELSATMEQVHTVKKYRQY
                     YKEYKASPSDKAFFEEYKAQITLYENALSELKKSYSKLPNSKGILDRLDKLQEKKNTL
                     MQEYSSSKSIMDELYKIRKNYGIYMGKEMER"
BASE COUNT          877 a          274 c          451 g          754 t
ORIGIN      
        1 aagggaggag gtgtttatta ttaaaggtga agtatccaga aaagatttga ttagagaaat
       61 tgaaaaagct attaaaagtg atgaattagg agcatttatt ggagcaggat tatcaattcc
      121 tgccggattt tgtagttgga aagaacttct aagagaacct gcagaagaaa ttggattaga
      181 tgttgaaaaa gaaagtgatt tggttaactt ggctcagtat tattctaatt caaaaaagag
      241 aacatcaata gatgacttga tcaaaggtca attttctcaa ttagtaaagc ctactgaaaa
      301 tcataaatta ttgtcgcagc tgcccatttc aactttttgg acaacaaatt atgataagtt
      361 aatagaaaaa gctttagaaa ataatatgaa aaagccttat gtaaaaacaa aggatgaaca
      421 attaagaggt acaaatcata attttgatgc gatagtatat aagctgcatg gtgatgtaga
      481 aactcccgaa gatgcagtaa taacaagaag tgattatgaa gagtttggat ataacaaaag
      541 aaaattattt agagaggttt tagaaggaga tttgcttact aaaacatttc tatttttggg
      601 atttagtttt gaagatccaa attttaacta tgtaattgga aggttaaggg tcttactcga
      661 tgaaaaaaat acaagaaaac attattgtat tatgaaaaga gtccaagatg ctgatgagga
      721 ttatgaatac aaaaaagcaa gacaggagct acaaattgaa gacctaaata gatatggtat
      781 ttttacatat ttagtaaata aatatgatga aatcaccgaa atattgagca ctcttgtcga
      841 tagatttaga aggaaaacaa tatttatatc tggtagtgcg tactcctatt cggcttattc
      901 tcagaaaact ggcgaaaatt ttattcataa actatctttt gaactatcaa aaaatggtta
      961 tcatattgtg aatggatatg gtaaaggagt cggtgaattt gtattaaatg gagttgcaga
     1021 ttattgtttg actcacaagt ccaaaataaa tgatttttta acacttatgc cttttcctca
     1081 aaatagttca ttaggtattg atttagataa gctatataaa gaaaatagag agcagatgat
     1141 tgaaagttgt ggtatagcta tatttctttt tggtaataag gaggcagaag atattgcaag
     1201 cggagttatg gacgaatatg agttatcaaa aaagcatgga ttagtatgtt tgcctattga
     1261 atatactggc ggtgcatcta aagaaatata tgatcaaaca actcaagaaa tttcagataa
     1321 aaatacaata agtgcaattg aacaggcaaa taaacaatgc gatggcgata ttgatatgtc
     1381 tgttaaaaac atagttcaag cagttaaaat attaaataag gaggaatttt aaatggcaaa
     1441 aagacaggta ttttttagct ttcattacga caatgataat tggagggcag gacaggttcg
     1501 caatatgggg aaagtagaca gtagttctac cttttctgat aatgactggg aggaagtaaa
     1561 agaaaaaact gaaagtaaaa ttaaagaatg gattgatgaa cagttaaata agcgttcatg
     1621 tttggttgtt ttgattggag aaaaaacagc gaacagaaaa tggataaatt atgaaataag
     1681 aaaagcatat gagttaaata aaggtattgt gggaatttat attcacaagt tggagaattc
     1741 actgggagag caagatgata agggtaataa tccttttgat tatttaacat tagaaggtga
     1801 aaaactttca aagtatgtta aatgttttga ctccaactat tcatcaagta aatatgttta
     1861 tagcgatatt aaagataata ttgaaggttt aattgagtat ggaataaacc ataaaccatc
     1921 aacttggtaa taaatgatga tggagagaaa aaattatctc tccatctcct tacccatgta
     1981 aattccataa ttttttcgta tcttgtaaag ttcgtccata atagattttg aggaagaata
     2041 ctcttgcata agggtattct ttttttcttg caatttatca agtctatcta aaataccctt
     2101 agaatttggc aacttggaat atgatttttt aagctctgaa agggcatttt catataaggt
     2161 aatctgagct ttgtactctt caaaaaatgc cttgtcagat ggacttgcct tatattcttt
     2221 gtagtattgc ctgtattttt taacagtgtg aacttgctcc atagtggcag aaagctcctg
     2281 catttcctta tcaatagcct tgatcttatc ctgtaaattt tgcctttcat cggctgcttt
     2341 tatgatatat ttcgat
//
LOCUS       DARYVE010000108         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYVE010000108 DARYVE010000000
VERSION     DARYVE010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVW25_001918"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVW25_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1379502.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVW25_001919"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVW25_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1379503.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          557 c          389 g          644 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagc caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYVE010000109         2209 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYVE010000109 DARYVE010000000
VERSION     DARYVE010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2209
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            128..1564
                     /locus_tag="TVW25_001920"
     CDS             128..1564
                     /locus_tag="TVW25_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1379504.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            1817..>2209
                     /locus_tag="TVW25_001921"
     CDS             1817..>2209
                     /locus_tag="TVW25_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1379505.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGN"
BASE COUNT          941 a          282 c          472 g          514 t
ORIGIN      
        1 ttagaaatga tgagacgtta taaaaaagag gaaaaacaag aaaaaatgaa gttacaggaa
       61 atgagaaata cagaaaatca taataatatg gaggaaaatc atgaaaatca aatggaagaa
      121 taaaaaaatg gcgataacat tgtccggagt aatctttttg atacttgctt tacttggaac
      181 aatgcttttc aatcaccaga ttgtttttgc acaaggtagt ttaatcccga cactgattag
      241 tcccacagaa gttttagctc aaactaaagt ggaggttaag ataaaatata tatttaagga
      301 tgagagtgta tataaggaag aaataattga agtagaaacc gggcaagttc ttgacagtgg
      361 ggacctacca atgttagagg ataatatgaa atttattgac gaatttttgt tctataaagt
      421 aaagggagac ggtacagatg agattatccg taaagtagaa aaaattacag ttaaggataa
      481 agaaattcag acagaagagg aaaagccaaa acaggacgaa agcactgaga cggaagataa
      541 aaaaacagaa gataagggaa cacagacaga gctttctaaa gatgatattt ccaaaatgga
      601 aaaagaggca aaagagcttc aggataaact tgataaatta aatggtgaaa tcagggataa
      661 agacaaacta agcgataaac agaaagaaaa aatcaaagac cttgaagctg agattgaaag
      721 tctgaaagaa aaaatgaaga aagataaggg aaataaagac ttatcagaag atatgaaaaa
      781 ggaaatagat aagctgacgg aaaaggtgaa agagcttgag aaaaagccaa ctgaaacaaa
      841 caaagctcct gtaacatcac agtctgttac accgattagt cctatttcag ggattaagac
      901 aagctcaggt atttcttctc aaacaccaca gagttccggt aaaggttcat ctgatgcagt
      961 aagctccggc aatactacaa aagatacagg taaaactgaa tcaaaggaga aagaaaagga
     1021 agttcgctat cccaataagc tgacaccgaa agctcctgct aataacagta gtcaggattc
     1081 atcaatggac ggtgcaagta gcaatgtaaa taccaataag ggtgtggctt cagctccgtc
     1141 aaaggcaaga ggaactgtta cagaaaataa agataatgcg aataatgatt atccaattca
     1201 tcatggggat agcagcgata acaaagaagc agataagtat tcagcagatg caagacaatt
     1261 tattactttc cagacaaaat ccggaaagac atttcattta atcatcaatc acgatgagca
     1321 aagtgaaaat gtaatgcttt tgactgaagt atctgaagat gatcttctga atatggtaga
     1381 gaagaaggaa aacccgcaag aagaaatcaa aaaaatggaa gaaacggtac cggaaagcga
     1441 agtaaaaaaa gaagagccga aaaaggaaga aggtaaaggt agcggctcat atattttttt
     1501 aggaatcatc gttcttgcag tagttggagc aggatattac tttaaaatct acaagaaaaa
     1561 gtaggaagat gatgattatg atgaagatga ggaagaatat gatgaatttg aagatgagta
     1621 tgaaaaagag gacgatacag aagatttgga agaaacagta gaagaacagc ataacataga
     1681 tgatatggca atcgactctt atgatgaaga agatgaggaa taaagttata aaaagagaaa
     1741 tgtaaaccct gatgttgcgt ttacacttaa aaaatggtat aatgcaagtg taaacgcaac
     1801 aaagggggtg gatgggatga attatgaaaa taaaattgaa aaatatttga agcaatcagg
     1861 tggaattatt acaacagcat actgtaagga aaataatata ccgacgatat atctcagtcg
     1921 actattgaaa gatgggagat tgtcaaaagt aagaaaagga atttatataa cgaaagatgg
     1981 ggattacgat gagtattatt tctttcaaca tcagtataaa aaggcgatat tttcttatga
     2041 aacagcactt tacctgcttg gacaaacaga taaaattcct tggagtatcg atgtaaccgt
     2101 ttataacgga tataaattta atgaaaaacc gaacggtttc aatgttcatt atgtaaaaaa
     2161 atcaatttat gacttagggg taacccaaaa acctacaatg tttggaaat
//
LOCUS       DARYVE010000110         2136 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYVE010000110 DARYVE010000000
VERSION     DARYVE010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2136
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            131..532
                     /locus_tag="TVW25_001922"
     CDS             131..532
                     /locus_tag="TVW25_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1379506.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            988..1155
                     /locus_tag="TVW25_001923"
     CDS             988..1155
                     /locus_tag="TVW25_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1379507.1"
                     /translation="MCEEHNIDIKMEIDKKDKQTINQIDGWNIEVKFNENGLSLENLV
                     EEYIKEKFSVY"
     gene            1254..>2136
                     /locus_tag="TVW25_001924"
     CDS             1254..>2136
                     /locus_tag="TVW25_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1379508.1"
                     /translation="MFKDSVNKENIAVMYLRLSKEDGEKTESNSISNQREMINSYAKK
                     NQFIIIKEYVDDGYSGATFDRPNFKEMINDAYDKKFDTIIVKDLSRFGRDYIEAGKYI
                     QRIFPENGIRFISVNDNYDSKSADMNDTHLILPIKNFINDSYCRDISNKVKSSQKIKR
                     EKGDFISAFAPYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLG
                     VLTPRKYKESQGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKK
                     QIEREKEDWIRVENTHDA"
BASE COUNT          872 a          233 c          409 g          622 t
ORIGIN      
        1 aatatagaac aaataagact ttatattttc atttttattt tagaggatct tgcacgtcaa
       61 aatgcagagg tcctcctttt ttattcaaaa aataagtttg aaatttttga taaaaaggag
      121 ggctttacaa atggcagtta aaagaaaata tatctatgta aaaggtcaaa agatttatgt
      181 acctgacgaa gtgtatagag catataaaaa agggcttaat catgaaactc atttaaagag
      241 attggataga aagcatggcg tatttcgttt tggagacttt aacacaagta ttgtagatat
      301 tgcagataat actgttgatg ttgaaaaaat cattgaaaca aaaatgctga tagaagatct
      361 gtattatgca ttagacagtt taaatgatga agagagaaaa ctaattgaag cactatattt
      421 tgatgataaa actctcacag aagttgcaaa acaaagagac acaaatccaa tgaaaatcag
      481 tagattaaga aataagattt tagaaaagct gagaaaattt ttggataagt aaattaagta
      541 gagggcaggg aaacatctct gtcctctatt tttgaaaatt tttcaaaaat agtgttaaaa
      601 gttgtcctga aagtaaggtt tatatataga gggactttta ttacctcgtt atatatagat
      661 ttgatctttg acaactgaat agaccaagac aagactttaa ccagtagtgg agcaatttat
      721 aaacttacgc caagataaac ctgctaagtt aaattgattt aaatgaatac ctacatttgt
      781 agaggatata aggtttggag cgataaataa gtctgtataa aaagagggtg gcaactcttg
      841 tgcgatgata ctaatgggga taatgatact tctacagttg aagccggctc atcttgaaaa
      901 gaggcggagg tgaaattcct atgtagcagc caatgcactt gtcaatgtca taaaacttaa
      961 aaatattgaa gataaggaga agatattatg tgtgaagaac ataatataga tattaagatg
     1021 gaaatagata aaaaagataa acagacaata aatcaaattg atggttggaa tatcgaagtt
     1081 aaatttaatg aaaatggatt gagcttagaa aatttagtag aggaatacat caaagaaaaa
     1141 ttttctgtct attaggggct gacaaaaaat ataaggagcg ttataatatt tttgtggaag
     1201 cctaaccttg gttcgattta ttgtatgtaa attgaattta aggaggcttt tttatgttta
     1261 aagacagtgt aaataaagaa aatattgcag ttatgtattt gaggctttca aaagaagatg
     1321 gagaaaaaac agaaagtaat tctatatcca accaaagaga gatgataaat tcttacgcaa
     1381 agaaaaatca atttataatt atcaaagagt atgttgatga cggatattca ggagcaactt
     1441 ttgatcgtcc taattttaaa gaaatgataa atgatgctta tgataagaaa tttgatacga
     1501 ttattgtaaa agacctatca agatttggaa gagattatat agaagcaggg aaatatatac
     1561 aaagaatatt tccggaaaac gggataagat ttatatctgt aaatgacaac tatgatagta
     1621 aaagtgcgga tatgaatgat acacatctaa tactccctat aaaaaacttt atcaacgaca
     1681 gctattgccg agatatttcc aataaagtaa agagttctca gaagataaaa agagaaaaag
     1741 gggattttat cagtgctttt gcaccttatg gatataaaaa atctgatgag aataaaaata
     1801 agttggtggt tgatgaacaa gctgctccta acatcaaaaa tatatttgat atgaagctct
     1861 tgggatattc ctcaaaggca atcgcagatg aattaaatca cttaggtgtt ttgactccga
     1921 ggaaatataa agaaagtcaa ggctttaagt gtaatggatt tcaaaatata aaaggtggta
     1981 attggtcagc aaagtcagta aacagaatta tagaaaatga agtatatatt gggaacacct
     2041 tgcaaggcaa aagtgttacc ttaaactata aaaataaaaa acagatagaa agagagaaag
     2101 aagattggat aagagtagaa aatactcatg atgcaa
//
LOCUS       DARYVE010000111         2105 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYVE010000111 DARYVE010000000
VERSION     DARYVE010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(109..792)
                     /locus_tag="TVW25_001925"
     CDS             complement(109..792)
                     /locus_tag="TVW25_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEL1379509.1"
                     /translation="MLLDVVIQFRDRRSTITIDTPSTCPHCGRTMSPQHVGESKSSDN
                     ESYSYQGHFSVIFRCSFDDCLKYFAVEYIHDQIGKGSAVAYFYRPPIRVNLPENVDKV
                     SPAFVEIYSQATIAEQEKLDQIAGVGYRKAAEFLIKDYTISKNPDDSDNIKQIMLGKV
                     ISDYLSDFPKLQALSRSVAWIGNDETHYVRRHNNKDLQDLKRFILAAAQFVAADYDAD
                     DALSFTSTD"
     gene            850..1038
                     /locus_tag="TVW25_001926"
     CDS             850..1038
                     /locus_tag="TVW25_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379510.1"
                     /translation="MEETASVNVTVKINNITEFSTLVEKFNEKARELEAISHELMRFK
                     FQGEIESRALSDNANEIE"
     gene            complement(1012..1479)
                     /locus_tag="TVW25_001927"
     CDS             complement(1012..1479)
                     /locus_tag="TVW25_001927"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379511.1"
                     /translation="MDLNQVRLLEACHRYLVDRVHIDIKENMLNDKLVFEFNGDFVTF
                     NTYQEVGHCCFYEYELGSYEELENHRSIDVTEILSILNLKSGQIGTLSMLTDITRVRA
                     YIFKLLSQADFAKFEKEIKNTNFAYNFRYVENYSYLPCVKIDKDKLFNFVSII"
     gene            1553..1741
                     /locus_tag="TVW25_001928"
     CDS             1553..1741
                     /locus_tag="TVW25_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1379512.1"
                     /translation="MQILLYKLRKEKRISQEEMSKVINKSSNTYRDKELGKRDFTQSE
                     MFKIANFFHKELGEIFTP"
     gene            1792..>2105
                     /locus_tag="TVW25_001929"
     CDS             1792..>2105
                     /locus_tag="TVW25_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HEL1379513.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSP
                     EK"
BASE COUNT          728 a          367 c          395 g          615 t
ORIGIN      
        1 tggaaggagg aacgatatga acgaactaga aagaacagcc cttaatgaaa tcatgaggac
       61 agtgacttat atagcggaga agctggataa aattgattct aagatttctc agtctgtaga
      121 agtgaacgat agtgcatcgt cagcgtcgta gtctgccgca acaaattgag cagctgctaa
      181 aataaaacgt ttgagatcct gcaagtcttt attattatgt ctacgaacat aatgagtttc
      241 atcgttacca atccacgcca ccgagcgaga tagagcttgg agtttaggga agtcggagag
      301 atagtcacta attacttttc caagcataat ttgtttgatg ttgtcgctgt cgtcaggatt
      361 ctttgatatt gtataatctt tgattaaaaa ctcagcagct ttacggtaac caacacctgc
      421 aatttgatcg agtttttctt gctctgcaat tgtagcttgg gagtatatct ctacaaatgc
      481 tggcgacact ttatcaacgt tttcaggaag attcactcta ataggtggac gatagaagta
      541 ggcgacagct gatcctttac caatctgatc gtggatatac tctacagcaa aatattttaa
      601 gcaatcatcg aaagagcaac ggaatatcac tgaaaaatgc ccctgatatg aataactttc
      661 attgtcagaa cttttgcttt cgccaacgtg ttgaggggac atagttcgac cacagtgggg
      721 gcaagtcgaa ggtgtatcaa tcgtgattgt acttctacga tctctaaatt gtataactac
      781 atcaagcaac attattattt ctctccaatc gttttattta aattatacca cagaaagggg
      841 gtggggaaga tggaagaaac agcctcagta aacgtaactg taaaaattaa taacataact
      901 gagttttcaa ctttagttga aaagttcaac gaaaaagccc gtgagttaga agcgatttct
      961 cacgagctaa tgcgtttcaa atttcaaggc gagattgaaa gtcgtgcgct atcagataat
     1021 gctaacgaaa ttgaataatt tatctttatc aattttaacg cacggtaagt aactataatt
     1081 ttcgacatat cgaaaattat aggcaaaatt agtatttttg atttcttttt caaattttgc
     1141 aaaatccgct tgggatagaa gtttgaaaat ataagctctt actcttgtta tgtcggtaag
     1201 cattgagagt gtaccaattt gccctgattt taagtttaag atgctcaaga tctcagtaac
     1261 atcaatactt ctgtggtttt ctagctcttc atatgagccg agttcatact cataaaagca
     1321 gcaatgccca acttcttgat atgtattgaa agtcacaaag tctccgttga attcaaaaac
     1381 tagtttgtca ttaagcatat tttctttgat gtcaatatgt actctatcaa caagatatct
     1441 atgacaagct tccaataatc gaacttgatt taaatccatc acattcacct cctttctgcc
     1501 catattatag cagattagag gtactaaaaa cagatagaaa ggaggtgggg gaatgcagat
     1561 tcttctgtat aaactgcgaa aagaaaaaag aatttcacaa gaagagatgt ctaaggttat
     1621 taataagtct tctaacactt accgagataa agaattaggt aaaagagact tcacacagag
     1681 tgaaatgttt aaaatcgcca atttctttca caaagaatta ggcgaaattt ttacaccata
     1741 aacttcacga aacgtgaaat ataaatcaac acaacactag aaaggaacaa catgaatcaa
     1801 ctaataaaca tcaccctaaa cgaaaatcaa gaaccagttg tcagtggtcg tgatttacat
     1861 aaagtacttg aaatcaaaac agcttataaa gattggtttc caagaatggc tgaatatggt
     1921 tttgaagaag gtcaggactt tagctcattt ttgagcaaaa gtacaggagg tcgtcctagt
     1981 caagaccacg ttctaaaact agacatggca aaagagattg ctatgttaca gcggaatgaa
     2041 aaatctaagc aagtccgcaa gtattttatt caaatcgaaa aagactttaa cagccccgag
     2101 aaaat
//
LOCUS       DARYVE010000112         1994 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYVE010000112 DARYVE010000000
VERSION     DARYVE010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..349
                     /locus_tag="TVW25_001930"
     CDS             <1..349
                     /locus_tag="TVW25_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HEL1379514.1"
                     /translation="SHTDGFVVIGFSKKELGIDIEKVNDGFAFEDILENCFTSREIKN
                     IGSNIPMFYRYWTAKEAYLKYEGYGLIRNPKEIEVIYIDNQRIKIEDKVKRSNKDLIA
                     FSISSKYFGAICI"
     gene            358..1941
                     /locus_tag="TVW25_001931"
     CDS             358..1941
                     /locus_tag="TVW25_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1379515.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
BASE COUNT          742 a          224 c          427 g          601 t
ORIGIN      
        1 ttcacatacg gatggatttg tagtaattgg tttttcaaag aaagagcttg gaatagacat
       61 tgaaaaagtg aatgatggct ttgcgtttga agatatactt gaaaattgct ttacatccag
      121 agagattaag aatataggca gtaatatacc aatgttttat agatattgga cagcaaaaga
      181 agcctaccta aaatatgaag gatatggtct tataagaaat ccgaaagaaa tagaagttat
      241 ttatatcgac aatcagagaa taaaaattga agataaggta aaaaggagta ataaagattt
      301 gatagcattc agcatttcat cgaaatattt tggagcaatt tgcatatagg aggaagtatg
      361 aatatagaat tgaaagaaaa tttagaaaaa aattatgatg acaatgtttg ggaacatgtg
      421 accttgggag agtttgttgc gaactgtgcg gaaacgtata aagataaaac agcgattgta
      481 gatggagaat taaacttatc ttatgatgag cttgataaac tttcgaataa gtatgctaat
      541 ggactactta aagcaggttt taaaaaagga gataagattg tattacagct tccaaattgt
      601 tatgaattta tagtgatatc ttttgcaatg tttaaaacag gaattattcc gattatgagt
      661 ttgcctgcac atcgaaagaa tgaattaaag ggtattatag aaaagtctga ggcggtagca
      721 tatatttcaa aggataaata tttaggtttt tcatatgtgg atatggttcg ggatatgaaa
      781 tctgaattaa atacgaactt ggagatttat attcttggag aaagtgaaga atataaaaat
      841 ttttcgtcac ttattgagaa tgattgtttc tataaatatc cggatgtcga ttacaggagc
      901 ataggattat tgttattatc tggcggtaca acaggaatac cgaaactgat tccaagaaga
      961 cattgcgatt atatctatgt tgcaaagaaa acgacggacc ggtgtaacgt aaatcaggaa
     1021 agtgtatatc ttgcttcttt gccaatagct cataattttc ctttggggtg tccagggata
     1081 atgggtactt ttgcaaaagg cggaaaggtg gttttgtgca atgtgacaag ccctgatgaa
     1141 attttacctt taattgagga agaaaaggtt acgataacag gatttgttcc tgcaattgcc
     1201 aatatttgta tggattattt agagtatgaa gagtatgatc tttcctcttt ggaggttata
     1261 caagtcggag gttcagtttt ggaaccttgg ttggcagaaa aaattgaaaa agtttttgat
     1321 gttaaactac aacagatttt cggaatcgct gaaggattga tcttgacaac aaatgaagaa
     1381 gataacgata aaataagatg gcaaacacaa ggcaaaccaa tcagtgaaca tgatgaaata
     1441 ctgattgtgg atgaacaagg aaaaattgta gggattgaag aatatggaga acttatcgtt
     1501 agaggtcctt ataccattta tggttattat aatcttcctg aagtaaatga aacatgtata
     1561 acacaagatt gttattttaa gactggtgat aaagcacgaa aactaaaaga tggtaattat
     1621 caaattgtcg gaaggatcaa agaaatcatc aatagagcag gtgaaaagat aacaccactt
     1681 gaattagaag aaattttgct tactcatgaa aatatcaact cggtacaagt tgtagggctg
     1741 ccagatcgtc tgcaaggaga atccattgct gtatttattt taaatggaga taaggagctt
     1801 acactggaag aagttagaaa attcttgatt tctaataatg tggcggattt taaattgccg
     1861 gatactgtta aatatattga tgcgtggcca ttaacagctt tagggaaaat agatagaaat
     1921 aaattaaaag aaacttttta aaggaggatt ttggaatgga acttaacaat ataaaagaaa
     1981 gagctaaaga atta
//
LOCUS       DARYVE010000113         1912 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYVE010000113 DARYVE010000000
VERSION     DARYVE010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..413)
                     /locus_tag="TVW25_001932"
     CDS             complement(<1..413)
                     /locus_tag="TVW25_001932"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379516.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPV"
     gene            complement(829..1695)
                     /locus_tag="TVW25_001933"
     CDS             complement(829..1695)
                     /locus_tag="TVW25_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1379517.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          602 a          368 c          266 g          676 t
ORIGIN      
        1 acaggtatca attcatacaa gtcacttaat aattgtttac agtgttctct atctctggga
       61 taaattgtga tgaatttccc agattccgaa ggatcttcca tatcggatac attttctaaa
      121 atcatttttt cgtcttttaa atatttaaaa gaaatatgat gacattttaa atacggaaat
      181 actacagaaa aaattgcttt atagttttga aatgttcctg aaatatgaat tttaaatcca
      241 tattcaggta aaacataatc attcgtctct acatatctaa agcttgtcag atccatatgc
      301 ttcaccatgt accagctgaa taaatgggta cttctctgga tgctccatga ttgtcttaac
      361 tttcttttcc acgtaggctt caaagctttt ttcaaagcta cttgaacact cacgagaatc
      421 ttctttatag atacattttt aagtaatcat tggttttctc atagcaatac atctcctcag
      481 tcttattagt ataaaactaa aaacgctcac attaacaggt ctttttgagc gtttttagta
      541 ggactagtta ctaaattatg gtttgtagat tggacatttc caagtcacaa caaagccttt
      601 cactggcgca aagcatctac tagcctcgta tgcaaattga gtcatgtttg tgatctcctt
      661 tcattcttga tgagtctagt gtatcatcaa aaaccgtacc aaagctaaac tgttcatatg
      721 ttcaaatcat ggttttgaca ttaatcaaaa aacagtagct caaaaagcca ctgtttgcta
      781 ctagctaagc atctaaacca ttttgcttat caatgcttta agttgcattt attcaacttc
      841 ctttaaccat ttctctaaac tatctgaata ataggctgca ctttcatcac aatttaatgc
      901 ctttaagatg tgtatggcgt catttatttg ctttaagcct agttcctttt cccctttaca
      961 atataggtgc tgaccatcag caatcatata aacaattctt aagtaggtgt cattttcttc
     1021 aaaaaaatga ttgttaatca ttttatcaaa atatgcagct atacctagcc ttttttcctg
     1081 agtagcttta aacagcccat ttaataaaat gctgtgcact aaatttcgat gctgccaaag
     1141 ctcctcaaaa aagtctactc ttcctagcat ttctcgagta taccgcaaat acacatccaa
     1201 ggataataag ggagaaatat ctgaaaataa ttgtaattcg tatattcccc aaatctccac
     1261 tgaaaacaaa taatcatata aaaagctttg ctcatctgga gtcattttga tattctcgtc
     1321 taaaaagagc atttggcttt taatcatcaa agcatttaaa aaatagatat cctttttgta
     1381 taaatgatac tgctccagct cttttgtata caattgatgt aagctggaca ggtctttttt
     1441 tgatatggcc tcccagatct cttgctttag gacagcatat ggggaaggct taaagccatt
     1501 tgctagatag ataaattcat tgagctctgt ccgaatattg ctaagtccaa ccaatagctt
     1561 tgagattgtt atatcggatt caccattttc aaatctgctt aacatcgagt gagaaaagtc
     1621 atctcccgtc gcttccttta acgatatgtg tcgcgatgtc cgcagtaatt taaacatttc
     1681 tcccatatat tgcatatcaa tacctcttca atctttcatt ttagtatagt atataacctt
     1741 aaaaatgtaa atccagtctt gattgcataa acctttaatt caacgtttga tgctactaaa
     1801 tatcctattt ttctgaagta gatcctcatc tttatgctat aagcacttgc tgcgttttag
     1861 aaaatgggct aaatcagcta tactcctttt taataacaaa aaagccttat tt
//
LOCUS       DARYVE010000114         1899 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYVE010000114 DARYVE010000000
VERSION     DARYVE010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1899
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..1797
                     /locus_tag="TVW25_001934"
     CDS             <1..1797
                     /locus_tag="TVW25_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1379518.1"
                     /translation="NYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDD
                     EEFTRNKDTKNNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLK
                     NKGIDGKSQSAKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKK
                     KNLKRQKKITKLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQ
                     KKYKDSVKNRIKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMG
                     TGMVSNTVSTTYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKI
                     GHNVHELLSYITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDA
                     DGNEHTESHEEPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEV
                     FGNIDLINSNGGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLG
                     FIGGNACDMYRNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDN
                     IGHIRVTTLDDWIATFCKHHPVGFGFPPSVQK"
BASE COUNT          798 a          219 c          403 g          479 t
ORIGIN      
        1 aattataatg actatgtaaa aaatccaaaa tctaagaata agaggtataa aaattatgta
       61 aaagacacat tttctaagga aagaatgaaa tcagaaaacc agaagaaata tgtgaggagc
      121 aactttgatg atgaagagtt cacaagaaat aaggatacga aaaataattt atttcaggac
      181 gtaaataata aaagaaaaac taccgataaa aattcatcac gaaaaagaaa aggaaaattt
      241 gaaaataagg aaaagaaaat atccaagtta cagcagaaaa agcaaagaca agagcaaaaa
      301 ctgaaaaata agggaattga cgggaaaagt caaagtgcta aaagtgcagt aatagcaacg
      361 ggtatggcaa agaggtattt ggaaagtgga aaagaggaca atgccggagt aggtactgct
      421 tataaggtta cagatcaggt cgaaaatatt tcaaggaaaa tatattatca tggaaaaaag
      481 aaaaatttaa aaaggcaaaa aaagataaca aaattaggta aaagcattga taaacaggag
      541 aagaaactct tttttcaaaa gaatatggaa gagatgaaaa aaagcgtgga ttaccaaaat
      601 acctcaaggc tcagacaatt ctttaagaga aggcaatata aaaatcagat tcaaaagaag
      661 tataaagata gtgtgaaaaa cagaataaaa aaatccttta tagagggcag taaaagattt
      721 ggcgaatttg taaagggcag agggaaaaag ataatatttc tatcactttt agcggtagga
      781 atatttttta tgttatttca ggctgggagc atgatgatga atatgggaac gggaatggta
      841 agtaatactg tttcaaccac ctacttatca tcagaagaca ccttaaaaga aatcaatcag
      901 aggttttcat ctttggaaca ggctttgcaa gaagaaatgg acagtgtgga ggaaaatcat
      961 ccgggctatg atgaatatat tatcaaagga aaagagaaaa ttggtcataa tgttcatgaa
     1021 ctcttgtcat atatcacagc ccgttatgga attgtaaaga atatttctga agtagaaagt
     1081 gaactaaaac atctgtttca aaaaatgtat acgctgactt ataaagaaga gattgaaatc
     1141 agatatagaa ctgttacatc cagctatacg gatgctgatg gcaatgaaca tactgaaagt
     1201 catgaagagc cgtatgagta taggaaactc attgtaacct tagaaaaaag agagatggac
     1261 ggaattatta gagaagcatt taagcgttat cctaataatt tggcacacta tgaaacttta
     1321 tttttgacac aaggaaatat gggagaagta tttggaaata ttgaccttat aaattcaaat
     1381 ggtggaattg gtggtggtaa agagtatgaa gcatcaagtg aagtgcaaaa gaaaatagtg
     1441 aatgccgctt atattacacc atctccagga gcaggttggt gtgccatgtg ggtatcacag
     1501 gtctatcaaa atgcaggact tggatttatt ggaggaaatg cttgtgatat gtatcgaaat
     1561 tatactttta cttctgatag gtcaaagtta aaggttggaa tgcttgttgc agttgaaagt
     1621 agcagtagtg gtagcagttt aggtgttacc tatggtcatg taggtattta tatcggagat
     1681 ggaaaagtaa tggataatat cggacacata agagtaacta ccctagatga ttggattgca
     1741 acattttgca aacatcaccc tgtaggtttt ggatttccac catcagtaca aaaataagga
     1801 gggaatattt tgaataaaaa atatagaaaa aatatagaaa agcaaaaaga tattcagaaa
     1861 aaaatagaag aactccagtt aaaacaggag atgttaaaa
//
LOCUS       DARYVE010000115         1849 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYVE010000115 DARYVE010000000
VERSION     DARYVE010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1849
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..273
                     /locus_tag="TVW25_001935"
     CDS             <1..273
                     /locus_tag="TVW25_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379519.1"
                     /translation="TIHVLTSGGKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKH
                     EDLAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            286..576
                     /locus_tag="TVW25_001936"
     CDS             286..576
                     /locus_tag="TVW25_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379520.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            579..758
                     /locus_tag="TVW25_001937"
     CDS             579..758
                     /locus_tag="TVW25_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379521.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            870..>1849
                     /locus_tag="TVW25_001938"
     CDS             870..>1849
                     /locus_tag="TVW25_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1379522.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKS"
BASE COUNT          539 a          350 c          466 g          494 t
ORIGIN      
        1 actatccacg ttttgacaag tggtggcaag attgagcctg atatctataa aggcatgctt
       61 gagcttattg agccagctaa aaaaggtcag tatcaagagc atgatgtctt tactgtgcta
      121 gatgacaagc atgaggactt ggccggcgag ggtaaacttg tctttgtcta tgttaacgag
      181 gcctttgagt acgacaagca aaccctcaaa gatctggaat cagaggataa agtcacagtt
      241 atcaagtacg ctgatttggt taaaggcaaa tagtgaggtg attagatgat agattttgtg
      301 caaataggca ctttttgtgg cgctgctctg tctatctttg gtgtttgggg atttatcgtc
      361 aatcctttta aaaaagcgct ggaggctaac gagctagcca tggcccaact caaagactcg
      421 atcaaggagc tagcctacga gctaaaaaat cttgatcgtg atggagagat aaccaaaaag
      481 attatcgatc ggcatgagga gcgtttagga cgtgtagagg acgacattat tgtcaataaa
      541 gagcaaatca aaacattatt taaaaaagga gactaaaaat ggataaatgg tttaaaaaag
      601 tagcaatcaa aacaattaag acaatggccc aaaccgctgt aggggttatt ggatcaagcg
      661 cattgattac tgacgtcaac tggcaggtgg tggcctcaac agttattatg tcaggtattg
      721 tctgcgtctt gatgaatgtg tctgacatca aggaatagca ttatgcgagc aatcacacga
      781 ttagcaatag tcctagcaat cgcaatacta tatttaccgc tatctgtgat tgctcttatc
      841 ttttatccgt ttttaggtga ggaggacaga tgaccttttt agacgacata aaaagcgcag
      901 ttatcgcaga gtggcacaat cataagattt tgccatctct gacggctgct caagctattt
      961 tagagagcgg ttggggcaag tatgccccac ataacgcatt gtttggtatc aaggcagata
     1021 gctcatggtc tggtaaatct tttgatacca agacacaaga ggagtatcag ccaggtgtcg
     1081 tgacggatct cgtggaccgc tttagagcct atgacagttg ggacgagtca atccttgatc
     1141 atggccagtt tttagtggat aatccacgat acaaatcagt tatcggggag accgactata
     1201 aaaaggcttg tcatgccatt aaagcagctg gttatgccac tgcaagtgat tatgcagagc
     1261 tgcttatcca actaatagag caaaacgacc tacaaaaatg ggacgcggaa gccctagcaa
     1321 aaagaaagga gtcacaaatg attagttcgc agtgtcgaga ggttatcgag ttttacatca
     1381 atttggctaa tgctggtatg ggtgttgata aggacggggc ttatggcacg caatgtgcag
     1441 atgtcccttg ttacgcagct aagcactggt ttggtgtcga tctctggggc aacgcagcgg
     1501 acttactaga tagcgcaagt gcgcagggct gggaagtcca tcgcatgcct acagatgcaa
     1561 atccacgagc tggggcattt tttgtcatgg acgcttggtt tggtggtatc aattatggtc
     1621 atacgggtct tgtgtacgtt gactcagatg gttacactat gcagactatc gagcaaaata
     1681 ttgatggtaa tgcagatgcg ttgtatgtag ggggtccggc ccgttttaat actcgtgact
     1741 ttactaatgt ggccggctgg ttttatcctc cttatcaggg agatgttgct gcacaaacgg
     1801 tcagcacaga cccgcaaacc tcagacacga tcgtagagac atcaaaatc
//
LOCUS       DARYVE010000116         1833 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYVE010000116 DARYVE010000000
VERSION     DARYVE010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1833
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(44..754)
                     /locus_tag="TVW25_001939"
     CDS             complement(44..754)
                     /locus_tag="TVW25_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1379523.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            complement(1201..>1833)
                     /locus_tag="TVW25_001940"
     CDS             complement(1201..>1833)
                     /locus_tag="TVW25_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1379524.1"
                     /translation="CVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHKVPTGWTGMAT
                     ALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIAVHLINIVSLE
                     TASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTFLCHIEVIGFS
                     SVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWKML"
BASE COUNT          598 a          343 c          278 g          614 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata tttaatattt tcttataact attgatgtta aataaatgaa aatatatcat
     1141 tcttgtttac taccaacttc taactagtat agtacgagga tataattaaa tcttcgtctt
     1201 ttacaacatt ttccaatata acgctagtgg taacaacaat aataatccaa tagctgatac
     1261 aatcgaacaa tatattgtca ttcttgcttt tgataaattt tcattttgta aaaccaccat
     1321 caagggtggt gcctgaaatg ggaaaaatac acttgaaaaa cctataactt caatatgaca
     1381 taaaaatgtt tttgaaacat tactaacgcc tgaaatatta tcaatcaaag gtgtaactac
     1441 tgccggaaca cccggtaaag ttactataaa tcctaatata atacacaata caacgaaaaa
     1501 agttaaaaca ttaaatgcac ttgctgtttc caaagaaaca atattgatta aatgcacagc
     1561 aatgacattt gcaagtcctg aagattttgc tatattccct aaacttatga ttccagctac
     1621 ataaaaaaat ggctcaaaat ttatttttct taaaggttgc ttttccataa aatttgaatt
     1681 tggtaacatt acaatcaagg cagttgccat tcctgtccaa ccggttggta ctttatgaat
     1741 atgttctgtc atccagaaag acagagttat aaataacaaa actattaaca atttctgctc
     1801 ttttgttatg tcaatggctt ttttggacac gca
//
LOCUS       DARYVE010000117         1751 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYVE010000117 DARYVE010000000
VERSION     DARYVE010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1751
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(215..1729)
                     /locus_tag="TVW25_001941"
     CDS             complement(215..1729)
                     /locus_tag="TVW25_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1379525.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          603 a          363 c          286 g          499 t
ORIGIN      
        1 tataacaaaa atccacttga aaggcttatc acaagtggat ttttcagaaa tattgtacca
       61 aataggcacg agctattgat tgctgctatt tagcataggt gttatcacga tcagcagtaa
      121 gccaatcaaa acaggtatcg ctaaagcaaa tcctcacaaa aaatggtcca aagaaaaacc
      181 tagcagcctt ataccacttg cttagcaaaa aaacttactc taccctatct ccaatcaaga
      241 gctgctctaa aagctgctcg taatgcttac gatgaaagtt cagaattgat tttaccactg
      301 tttttccctg ctccttaatg taatccatgc tcataccaat taagacgctc ttatctggaa
      361 atacctgctg ctcctcaaga aaaggcaaaa tattatcact cgtaatcaca aaatcaggag
      421 cctgctcata attttccaga ctatctgtta gcatgttgat acgagtaata ttaaccttat
      481 aagaaggaat acttgagata acaaagtaag acaagacatc acctaatgct ctcttgtttt
      541 caacgatgat gacctctaca ggcggcaagg acagctcaag catctgctcc aaatgaaggc
      601 acataaaatg caggtgccct ggtgagagcg tttctgactg gtagctaacc atcagccagt
      661 ccttgatttg ctcctcaacc ttttctagca gcagctgact gccttgatac ctctttgaat
      721 agtaatcctg aaagctaatc aaatcatgca attgaaagag acatcttctg aaaaagggaa
      781 gcaaaaaata catctgatcc cttaaatgaa gctgacgacc aaacaacatt tccaagcgat
      841 taacaagctc cttatacagc ggatcttctt ctaagatatt gtagacaaga cgtaattgct
      901 tgtcattcca ataatgcata agaaaagaac tatcaactgt aagataaacc aagtaaagat
      961 aatctaagtc accagaatta aacacaacct gagtacgtgt ctcaatttct tgcttagcat
     1021 agcaactgat ttgctcaaaa atagataatt cttttaaacg atcaaataaa gtaagctgtg
     1081 gtaaggatac atcataattc tgcctcttcc aagacagcat gagtaaaata tcaaaaagat
     1141 aaaatttctt gtccaagaaa acagtgggct ttaaccgcgt aggggttaaa aaaataaagg
     1201 catgaataat ttccatatcc ttaggtgtca tctcataaac agcaaaccca tactccttat
     1261 gaagcatggc aattaagtag cgaatccggt actcatcccc tataacccgg taatcatcga
     1321 tatccaaatg aatggattgc aggtagccct ttagcttatt gacaagatga taggcctttg
     1381 atttggaaat aaactgtctt ctgatgaaag ttgtcagaca ctttgtcctg taattatccg
     1441 tcaacagaaa cttcaacatt ttaagcgtat cagatgatgc ataaatactg tgaaaatact
     1501 tctccttgtt attaggatca aactcacagg taatgcctga cttcaataca gtaatagaca
     1561 ggtctttgtc aaatagtgca ttaatctgat taaggtattc cttagccttt cgaggggtta
     1621 ttgacgtctg cgagcacaat gaatcaagtg taatctcttt ttctgtcaat aagacagcca
     1681 atattagttt tcgctcaaca atatctcttt ctaaatagta atctaacaaa ataatctctc
     1741 tccttattag t
//
LOCUS       DARYVE010000118         1698 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYVE010000118 DARYVE010000000
VERSION     DARYVE010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1698
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            81..335
                     /locus_tag="TVW25_001942"
     CDS             81..335
                     /locus_tag="TVW25_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379526.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            354..752
                     /locus_tag="TVW25_001943"
     CDS             354..752
                     /locus_tag="TVW25_001943"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379527.1"
                     /translation="MKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQER
                     AAIYFSNTYENIHKIKIIGIDKNLKTGSMNKATIVNSKYYISVTFMGGEIYTGVEQAS
                     KDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            755..>1698
                     /locus_tag="TVW25_001944"
     CDS             755..>1698
                     /locus_tag="TVW25_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379528.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITAAHAKQPATVFN
                     APSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYFGDDELGISRWVDGKAGIG
                     RHSLAAYRFNSKGQVIDRKGRPAAAQAPALATLSSKLTEYRLLKKKYVASNGISSSEE
                     FYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEA"
BASE COUNT          583 a          303 c          377 g          435 t
ORIGIN      
        1 gaaattaagt ttgatagaca aaaatcctat aactcattta agttcaatag ataaaataaa
       61 agtaaaatat tggagtaaca atgatagtaa cagataaaaa ttataatgat atagccgatg
      121 gggtttataa ggttgatgct ggcaaagtta ttagaccttg gcgaaacggt aagactttta
      181 aaactaacgg gaaagattac cgcgtcctca aaacagaaga caaccccgac aatggtatgc
      241 aggctattgc tgtagctccg attaagggta gtgaggtggg taagagtcat atcatgattg
      301 tttatgtaaa aagcagctat tggctagcgt cctagcaata aaaggagttg atgatgaaaa
      361 agcaacaaag caaacgacgg aaactaattg gcatagtggc tttaataaca attttaggag
      421 gaatactaac aatgaattgg tttaatgacg aaaaactaaa tagagagcgt agagaacaag
      481 agagggcagc tatttatttt agtaatacat atgaaaatat acataaaata aagatcatcg
      541 gtatagataa aaatttaaaa acaggttcta tgaataaagc tacaattgtt aatagtaagt
      601 actatatatc cgtaacgttt atgggaggtg agatttatac aggtgtagag caagcttcaa
      661 aagacaatga ggaattttta aatcgtcgaa aaaaagcaga gaataagaca accttgagta
      721 aggacattga agttatttat aaggagaaat agtagtggtt agtgataaag attataataa
      781 actctctgaa aaagtatatg atgttgatgc taataaagta actatttctg ttagaaaaaa
      841 tacggatatt cttaatcgtt atgtcaaaat cctcaaagcc gaagataccc ccgacaatgg
      901 tatgcaagct atggctgttg taccaataaa agatggcaaa gaggatagaa gtcatatcgt
      961 cattgcctat gccgggacaa atagcagtga tatacgcgat attgacaccg atattcaatc
     1021 cgttgttttt ggagatgatc aatacctgtg tacccatgag gagcctgatt cttttaaagt
     1081 ggtcaagagt cagctaagta ctgctaaagc cttttccgac tacattagga caagctaccc
     1141 taacgctgcc atctcctaca ccggacactc tctgggaggc tatctggcac tcatcacagc
     1201 tgcccatgcc aagcagcctg ccactgtctt taatgcgcca agctctgtta ataacctctc
     1261 caaggaggct attgactttg ttaaagccaa caagggactc taccacagct accgcattaa
     1321 caatgactac attggaaatc tgggcactta ctttggagat gatgagctag ggatttcaag
     1381 atgggttgac ggtaaggcgg gaataggacg tcatagctta gccgcttatc gcttcaactc
     1441 aaagggtcag gtgattgacc gtaagggtcg tcctgccgct gctcaagcac ctgctcttgc
     1501 taccctaagc tcaaagctaa ccgaataccg cctgctaaag aaaaagtatg tagcctctaa
     1561 cggtattagc agctcagagg agttttacct tgatcagttt caggctcgag cagtcgcaca
     1621 ggctttggag cagaccactc agcttgccca agaggagatc attgctcgcc ggaaggaggc
     1681 ggttgcagag gcagaggc
//
LOCUS       DARYVE010000119         1698 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYVE010000119 DARYVE010000000
VERSION     DARYVE010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1698
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(182..724)
                     /locus_tag="TVW25_001945"
     CDS             complement(182..724)
                     /locus_tag="TVW25_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HEL1379529.1"
                     /translation="MNLDTVLQQMKECGAYDTWGTKKEVKALPEILSDDEIIQYATSG
                     FVNGNTVLVVLTQKRILFIDKGMLYGIRSTEIPLDMVNSVSYSKGLILGAIAVMNGAT
                     KIEISNIAKDTCPVLTEKIKDCVEQYKYNLYQHQSPQKTATVGSEDAVAEIRKFKKLY
                     DEGILTEEEFIAKKKIILGI"
     gene            complement(750..1535)
                     /locus_tag="TVW25_001946"
     CDS             complement(750..1535)
                     /locus_tag="TVW25_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1379530.1"
                     /translation="MNDKELALYIGSKIKELRKNKGLTQKELAILVNMGDTTIANYEK
                     GFRTPKKNTLFKLANALSVTIDELFPPINKKNKENIVHLKQQSNTTEINNKVALLDKE
                     LKEPRHSYWVKYGENLLSEQNTVGHSKNTVEEPQAAYYTYNYYDHAASAGTGQYLSDV
                     QVETIELPVDYDADFVIPVYGDSMEPEYHSGDYVFVKLSVELTDGDIGVFEYYGDAYI
                     KQLLINDEGAFLHSLNSKYEDIPVDRDSDFRIIGEVVGSYSEK"
BASE COUNT          493 a          316 c          274 g          615 t
ORIGIN      
        1 gacttttgga cgaggtcgtt tgaaaggata ttggcatcac cacctttgtg tgatataatt
       61 ttaggtacaa gaaaacgacc tttttaatgg ttgtttctta tacggtttcg cctcacgctc
      121 agactcgcca aagtttgaga gcgtggggct ttttttattt tttaacggtt aactttacac
      181 cttaaattcc taaaattatt tttttcttag ctataaactc ttcctctgta agaatgcctt
      241 catcataaag ttttttaaac ttacggattt cagcaacggc atcttccgag cctacagttg
      301 ctgttttctg aggcgattga tgttggtaca gattatattt gtattgttct acacaatctt
      361 ttattttttc ggtaagtaca gggcaagtgt ccttggcaat attagatatt tcaatttttg
      421 tggctccgtt cataacagct attgcgccaa gaattaaacc tttagagtat gagacgctat
      481 taaccatatc aagaggaatt tctgtcgatc taattccata taacattccc ttatcgataa
      541 ataaaattcg tttttgggtc aatacaacaa ggacagtatt gccgtttaca aacccagatg
      601 ttgcgtattg gataatttcg tcatctgaca aaatttctgg caaagccttt acttctttct
      661 ttgtccccca agtgtcgtaa gccccacatt ccttcatttg ttgcaaaaca gtatctaaat
      721 tcataataaa actccttata aaaatattct tatttttcag aataactccc cacaacttca
      781 ccaataattc taaagtcgct atctctatct acgggtatat cttcatactt gctatttaaa
      841 ctgtgcagaa atgccccctc gtcatttata agtagctgtt tgatataagc gtcaccataa
      901 tactcaaaaa cgcctatatc gccatctgtt agctctacgg atagcttaac aaagacatag
      961 tccccagagt gatattcggg ttccatggaa tctccataaa caggaataac aaaatcagcg
     1021 tcataatcaa ctggtaattc aattgtttct acttgcacat cacttaaata ttgaccagta
     1081 ccagcagaag cagcgtggtc gtagtagttg taggtgtagt aggcggcttg tggttcttct
     1141 actgtattct tactgtgtcc tactgtgttt tgttcagata aaagattttc accgtatttt
     1201 acccaataac tatgacgagg ttctttgagc tctttgtcta ataaagcgac tttgttatta
     1261 atttctgtgg tgttagattg ctgtttaaga tgtacgatat tttctttatt ttttttattt
     1321 ataggaggga agagttcatc tatagtaaca gatagggcat tcgcaagttt aaacaaagta
     1381 ttttttttag gcgttctaaa ccccttttca tagttagcaa ttgtagtatc ccccatatta
     1441 accaagattg ctaactcttt ttgagttagc cctttatttt ttctcagttc cttgatttta
     1501 gagccgatat ataaagctag ctctttatca ttcatttgaa ttcttctttc tttttattta
     1561 ataatagtat aacacataaa ttcacgtttt gaaaagtttt tttgtttttt cgaaaaaaaa
     1621 cagttgacac ttcacgaaaa gtgaagtaca atataatcaa gcttaaggaa ttaagcaaaa
     1681 taaaaactcc caagaggg
//
LOCUS       DARYVE010000120         1535 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYVE010000120 DARYVE010000000
VERSION     DARYVE010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1535
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            89..1225
                     /locus_tag="TVW25_001947"
     CDS             89..1225
                     /locus_tag="TVW25_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1379531.1"
                     /translation="MILEKNCNYIDDISRNNTFTVNPKMTYQFGHAFYLDSDLNYWNK
                     QWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNTDISSKIISVQNFTEDPVTKAID
                     VNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMYKVFEEGNAQDEWILKAIIQAAK
                     DDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAINYAHKQGSVVVASVGDEGANLN
                     NQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVTVGSVDGDGAISNFSNRGRNVVD
                     IFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLEGKYTYGYGTSIAAPKVAAALGL
                     IIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLLNITDFISK"
     gene            1262..>1535
                     /locus_tag="TVW25_001948"
     CDS             1262..>1535
                     /locus_tag="TVW25_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1379532.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGL"
BASE COUNT          521 a          204 c          321 g          489 t
ORIGIN      
        1 aaagcaatta aatgatcagg gaatgatagt gcttgatgaa attcctgaaa ttaatgtttt
       61 gacaatcgct gctgcaaatg actcatctat gattttggaa aagaattgta actatattga
      121 tgacatttca aggaataata cttttacagt aaatcccaaa atgacatatc agtttgggca
      181 tgcattttat ttagatagtg atttaaatta ctggaataaa caatgggata tgcaaagaag
      241 tattagtact agtagtaggt tttggcataa gtcatcaggt gaggtaacca ttggtgtaat
      301 agattctggt attactgata ataatactga catttcttca aagatcattt ctgttcaaaa
      361 ttttacggag gatccagtaa ctaaggcaat tgatgttaat aatgttttgg ataaaacagg
      421 tcatggtaca tctgttgttg gacaaatgtc ttcaaatggt tattatacag gaattgctcc
      481 aggcatgaag gttagaatgt ataaggtgtt tgaagaggga aacgctcaag atgaatggat
      541 tttaaaagca attattcaag cagcaaagga tgatgttgat gtcataaatt tgagtcttgg
      601 tcagtattta ttaaaggctt catcaaatat tgatgaagat agaactgctc taatcaatag
      661 ctatcaacgg gcaatcaatt atgcacacaa acaaggctca gtggtagttg cttctgttgg
      721 tgatgaggga gctaacttaa ataatcaagc tgagcttaag aacttagtca gtgctctcac
      781 aggaagagcg tttagttcag tcgatgggac aatagaggat attcccgcac agctagataa
      841 tgttgtgaca gtaggatctg ttgatggtga tggtgcaata tctaactttt ccaatcgtgg
      901 aaggaatgtc gttgatatct ttgcggcagg tggaggaagc aagaagctag cgcttcatgg
      961 ctatgacact tggattaaca ataaattatt tgagcaagat tgggttatta tcccaacact
     1021 agaagggaaa tatacttatg gctacgggac ctctattgca gcccctaaag tagctgctgc
     1081 cttaggttta atcatcgaaa aatatgattt aaaagataaa ccagatgagg ccataactat
     1141 tttgtatagt aactcttgga gtagcttgga tgataatgga aaaccaatta gattgttaaa
     1201 tattacagat tttatctcaa aatagtgtaa aataacagtg taactattat gaggtaagac
     1261 tatgtataag attctagttg ttgatgatga ttatgagatt ttaaaactta tgcggaccat
     1321 tcttgagatg aaaaattaca aggtaacaac ctatcaagaa gtgacttttc caatcaattt
     1381 tagagatttt caagggtttg acttgatttt attagatgtc atgatgccta atgttgaagg
     1441 tacacaaatt tgtcaattaa tccgagataa agttgcttct cctattatct ttgttagtgc
     1501 taaagatact gaagacgata ttattaaagg attaa
//
LOCUS       DARYVE010000121         1428 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYVE010000121 DARYVE010000000
VERSION     DARYVE010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1428
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            85..1344
                     /locus_tag="TVW25_001949"
                     /pseudo
     CDS             85..1344
                     /locus_tag="TVW25_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          440 a          342 c          265 g          381 t
ORIGIN      
        1 gggttatagg gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact
       61 aaactatcat ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga
      121 attaaagacc ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa
      181 ttgaaagctg tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc
      241 aagtacgact tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact
      301 ttgattcgcc tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct
      361 gagacttctc tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc
      421 cagcttctca tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc
      481 tcaaccgtca tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc
      541 gaacatatgt cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag
      601 gactttgaca ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc
      661 aaccacttcc tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat
      721 atgtttaccc cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt
      781 gatcgtttcc acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc
      841 atgaactctt ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg
      901 attcaacaag atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg
      961 catttgacaa acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag
     1021 cattatgacc tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt
     1081 ttcggcctga ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag
     1141 acctttttga aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct
     1201 aaactggagg ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg
     1261 aactttgaaa actttaaaag acggattttg atcgctatca atattaaaaa agagaagacc
     1321 aatttggtcc tctccagatg ttagcttgtc aactacccac tacagttgac atggagccgt
     1381 tagttattag tcaacccact acagctgaca aaaaatccaa atagtccg
//
LOCUS       DARYVE010000122         1415 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYVE010000122 DARYVE010000000
VERSION     DARYVE010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(362..856)
                     /locus_tag="TVW25_001950"
                     /pseudo
     CDS             complement(362..856)
                     /locus_tag="TVW25_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(1082..1154)
                     /locus_tag="TVW25_001951"
     tRNA            complement(1082..1154)
                     /locus_tag="TVW25_001951"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1119..1121),aa:Lys,seq:ctt)
     gene            complement(1156..1349)
                     /gene="ssrS"
                     /locus_tag="TVW25_001952"
     ncRNA           complement(1156..1349)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TVW25_001952"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          435 a          230 c          240 g          510 t
ORIGIN      
        1 atatttttaa gaagctgttt attaaaaata gataaataaa gtaaaaatta ccaagatata
       61 tttttagtgt tttaaaatta tgctaatatt tattgatatt ttaatataaa atatatgagg
      121 agataagaga ttgggaggtt gtgacaatcg agcggatatc cgatgttatg gcagaacttt
      181 ctgagtctga ataattttag ttcaccaaag aatcaagaaa gaaccattgg ggcaaaattg
      241 gggcataagt ttagaacttt tgtcgtttct tgtgtcgata caataccggt ttaatactaa
      301 caaatgcttt tattatcgac tttgtaacca ttattgttcc ttgtgttttt tcgggaataa
      361 actcaagaag tttttgagtt ttttcttgaa tttctttttc atatttcaat atgatgagtg
      421 aaattttatc ttctttggac atagtgttgt tgtcttcaag attaagttct ttagttgtta
      481 gagtgttttt atctaattta ttttgaaata ttgcaaaatc tagaattttt tgaagtaata
      541 cttcttcctc ggccatacgg ctataaagcc aattattttc gagtctctct aggtgctcca
      601 tccacttaaa gtctcttttt tctcctaaca tattgtaggg aaataaggta tcaatatcaa
      661 catttaaggc tgtagcaatc tcttgaagcc tatcccatga aggttcagta gtcccctttt
      721 cgtcattaat aattgtttgc ttagtaactc ctattaattt agcgagttct ttttgtgttt
      781 ttccagcttt taagcgagca tttttaatat ctatttgtcc aactgttaaa gcctgcgaat
      841 aattaaaaaa agccattttt ctccaaattc cgtcgcaggt gatggaggtg aaaatactcc
      901 gattgtatca ccttgtgtta attatattat tgtcatgtgt tagctctctt tttaaaaagt
      961 aataaattct ttatttaaca tcatatcata aaaaattgtt tcggggacaa atggtgggac
     1021 aaaccctctt taggcaagca aaaaagccct gcaataaagg ctttttgtcg tttttacact
     1081 atacccccta cagggctcga acctgtgacc catagattaa gagtctactg ctctaccaac
     1141 tgagctaagg aggtaaggaa agctgtattg gcaccggtga ttcacgtttt gtattgaacc
     1201 cgcacgatat aagcaggtgg gcaacatact tctcttcaga ttgcttccac gtgaaacggc
     1261 ttgcatacta gagatagact ttgtttccct aaaatacaaa aaaatagtcg gtcaacactt
     1321 agatgtgaat tcgtatgcca cagcaataac tctatgctct tatgatacca ctttttgaaa
     1381 atttttcaag ccctaaaatg aaaaaaagat cgtat
//
LOCUS       DARYVE010000123         1383 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYVE010000123 DARYVE010000000
VERSION     DARYVE010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1383
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..176)
                     /locus_tag="TVW25_001953"
     CDS             complement(<1..176)
                     /locus_tag="TVW25_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1379533.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSF"
     gene            complement(293..664)
                     /locus_tag="TVW25_001954"
     CDS             complement(293..664)
                     /locus_tag="TVW25_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1379534.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
     gene            complement(676..1287)
                     /locus_tag="TVW25_001955"
     CDS             complement(676..1287)
                     /locus_tag="TVW25_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1379535.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQAAAGLAKVS
                     AERTQKMINLQTIHMLTSVDKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEAFTYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            complement(1291..>1383)
                     /locus_tag="TVW25_001956"
     CDS             complement(1291..>1383)
                     /locus_tag="TVW25_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1379536.1"
                     /translation="LAEAEDEFTGAEIILIDNILEQYEANKKGE"
BASE COUNT          362 a          314 c          266 g          441 t
ORIGIN      
        1 ttaaatgact tacccgtcca agagctatct gccttgatac caaatagagc gttatgtggg
       61 gcgtacttgc cccaaccact ctcaaggatt gcctgtgctg cggtcaacga tggcaagatt
      121 ttatactttg tccagccatc taagcagcct tgcttaatgt catctaaaaa ggtcatctgt
      181 cctccttatc taaaaacgga taaacaatca gagcaatcac agacagcggc acatatagca
      241 ctgcgattgc taggactatt gctaatcgtg tgattgctcg catgagatcc tcctattttt
      301 tactaaacat atcaataaat tgcttaaaca gtgcgacatc aatccccatt ttgtttagat
      361 tttctaagat tgattttagc tcaaagagca gatagccaac gtacatgaca tacaaaaagg
      421 ctactcctgt atcatttggc agtaaaatcg acaaagggat aaaaaagatc atcagggcaa
      481 ttgagcaaat tttgcgcaaa ataccattaa tcccctcttt gctcctaaaa tcaatgttgg
      541 ggttaatttt tgctgcaacg gtacccgtta aaaaatcaat catcattgcg actgcaattg
      601 ctcctaaagt aaataggatt ttaccatctt gggtctggat taattgtctc aaaaaaataa
      661 acatggatca cctcactatt tgcctttaac caaatcagcg tatttaatca ctgtgacttt
      721 atcctctgat tccagatctt tgagggtttg cttgtcatag gtaaaggcct cattgacata
      781 cacaaagaca agattgccct caccggccaa atcctcgtgc ttgtcgtcta gcacagtaaa
      841 aacgtcgtgc tcctgatact gacctttttt ggctggctcg ataagctcta gcatgccttt
      901 gtaaatgtca ggctcgatct tatcgacgct ggtcaacatg tggatagttt gcaagttaat
      961 catcttttgc gtgcgctctg cggacacttt agccagacca gctgccgctt gtgcagttgt
     1021 tgctgtctta gcagtttcct gcgatagttt ttccaagtcg tccacttttt gcaccgcttc
     1081 gcccatggcg atttccacgt attcggattt tttaaattct tccaaggtag ctttgatgat
     1141 ctctgtgtca ttagttgagg ttaagtcctg cttgattggt tgagagatga ctgagccatc
     1201 ctctgctgta ataataacgt gagtgcttgc gactgctcct gtgctgtcaa attgtgggta
     1261 ttttcctgtg actttccaat tgcgcataat ttactctcct tttttatttg cttcgtactg
     1321 ctctaaaatg ttgtcgatta agatgatttc ggcccctgta aactcatctt cggcctcggc
     1381 caa
//
LOCUS       DARYVE010000124         1316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYVE010000124 DARYVE010000000
VERSION     DARYVE010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(146..538)
                     /locus_tag="TVW25_001957"
                     /pseudo
     CDS             complement(146..538)
                     /locus_tag="TVW25_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(535..1062)
                     /locus_tag="TVW25_001958"
     CDS             complement(535..1062)
                     /locus_tag="TVW25_001958"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1379537.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          423 a          330 c          254 g          309 t
ORIGIN      
        1 ggtaaagcac tagaaagcac tcaacagcag acaaaatagg agttggggca accgtcctag
       61 aagcattaaa aagcaacagc agcaaaaccg ttgctttttg tttaaatcaa agatacacct
      121 gtcctagcac ttataagctt gaaggaaaaa gaccaaaaag agaggtggaa gcacctgctg
      181 ctacggtatc tggtgtcagc cacatgataa aagcattccc cataatccct gaacacacat
      241 acagcagcaa aaactgtctt gacccccaaa tggtctcagc catccgcccg acaaaataaa
      301 gggttaaggt attaatgaaa aaatgctcaa agccaatatg aaccactata ggtgtcacca
      361 agcgccaaag ctgatcaggc attgctctga caacaagacc attcatgcca ccaaatataa
      421 caacagcata agggtgcgta gcaaactggc catagaccag ctgcattatc aaaaaaacta
      481 aaccagtcaa gcccaagaaa aagagtgtta tcgggtattt tttgatcatc agtctcattg
      541 gcaatacacc tccttcacag caatatcatg tgcctctacc acaaaatcct cccactgaca
      601 ggcataaatc gtgctaaagg tagccccctg ataatccctc aaataacgat catagtagcc
      661 accaccatag cctatacgat agcctgcagg gtgaaaaaca agccctggca catgaatggc
      721 atcaatctcc gacttagcaa cagctatggt acacctaggc tccataagac caaaagccgt
      781 ctgtatcaag tcacaaggat cataagccac aaacaccatc tctccacgag aacgagtctt
      841 gggcacaagg atagtcttgc cgtcctgcaa ggctcgctca atcagtagat ggctttgata
      901 ctcgtgtggc aagggcagat aggtcacaag agtctgcgcc tcttgatagc tgctactagc
      961 aactactgct gccaatagag ctaagtcctt ttccagctta tcctctgggg tcatcatggc
     1021 taggcgctga agcactagtt ggcgataatc ttttttaatc atgcccatat cataacacaa
     1081 agcgctgcta ctattcaaga atcggccaca atcaaggttc tttccttagt tgtcctacca
     1141 gacagggcag cagctcaatc agtgaatgtc cttcttactt cttgaggtga gcttgtggtc
     1201 tcatgagatc aaaaaattat ttttctaggt taagaaaagt ttaagcttta tgctatacac
     1261 ccgactttat cacttgtttt agtccacacc ttactcaacc ccttggtaga gtaagg
//
LOCUS       DARYVE010000125         1172 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYVE010000125 DARYVE010000000
VERSION     DARYVE010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..608)
                     /locus_tag="TVW25_001959"
     CDS             complement(<1..608)
                     /locus_tag="TVW25_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379538.1"
                     /translation="MFKTTVRILNWSRKYSTRIKKGFILSFLNSVFIAMPIMLSIYVF
                     NLVLGNYYGSTTYGNKEIAIVTTIMIGLVLGRYITAYFKSVNQDSIGYEMSADERVQI
                     GDILKRVPLGFFQENNPGELTTAVTTDLSFFENYSMKMIDIVINGYIMALVMIISISF
                     LSWELGVVAVSGVVLSYFCLLLLRKHSEKNSVFYLNAQSKLV"
     gene            complement(613..>1172)
                     /locus_tag="TVW25_001960"
     CDS             complement(613..>1172)
                     /locus_tag="TVW25_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1379539.1"
                     /translation="KDISLNQLNDLIGYVSQNNFLFNESIMENIRMGNPDASDEEVIE
                     VSKICACHDFIMELEEGYNSNVGSLGSKLSGGQRQRISIARMMLKNAPIILLDEATAF
                     IDPDNEEKIQGAINVLTKNKTLIVVAHRLSTIKNADKIVVLKNKTIFDTGTHDELLEK
                     CDLYKNMWLSHIGAKSKSIVSNIGG"
BASE COUNT          404 a          220 c          126 g          422 t
ORIGIN      
        1 tcaactaatt tactttgtgc attaagataa aaaacagaat ttttctcaga atgtttacga
       61 agtaacaata aacaaaaata cgaaagtact actccagaaa ctgctacaac acccaattcc
      121 caagataaaa aagaaatact gattatcata acaagtgcca ttatataacc gttaataact
      181 atgtctatca ttttcatcga ataattttca aaaaaagaca aatctgtggt tacggcagta
      241 gtcaattctc ccggattatt ttcttgaaaa aatcccaatg gtactctttt taatatatca
      301 ccaatttgta ctcgttcatc agctgacatc tcataaccaa tactatcctg atttacagac
      361 ttaaaataag cagttatata tctccctaaa accaatccaa tcattatagt agtcactatg
      421 gctatttctt tatttccata tgttgtactc ccataatagt ttccaagaac gagattaaaa
      481 acatatattg atagcattat tggcattgca ataaaaacag aatttaagaa agataatata
      541 aacccttttt ttattctcgt actatatttt ctagaccaat ttaatattct gacagtcgtt
      601 ttaaacattg cactaacctc ctatattaga tacgattgat ttcgatttgg ctcctatatg
      661 cgataaccac atatttttat ataaatcaca tttttcaaga agttcatcgt gtgtacctgt
      721 atcaaatata gttttatttt ttaaaaccac aattttatct gcgtttttta tagttgataa
      781 tctatgtgct acaactatta aagtcttatt ttttgtcaaa acattaatag caccttgtat
      841 tttttcttca ttatctggat ctataaatgc tgtagcttca tcaagcaata taataggagc
      901 atttttcaac atcattctcg ctatagaaat cctttgcctt tgtccacctg aaagcttact
      961 tccaagactt cccacattgg aattatatcc ttcttcaagt tccataataa aatcatggca
     1021 agcgcaaatc tttgatacct ctataacttc ttcgtcactt gcatcaggat ttcccatccg
     1081 tatattttcc ataatacttt cattaaatag aaagttattc tgcgatacat aaccaattaa
     1141 atcattaagt tgatttaatg atatatcttt aa
//
LOCUS       DARYVE010000126         1092 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYVE010000126 DARYVE010000000
VERSION     DARYVE010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            56..>1092
                     /locus_tag="TVW25_001961"
     CDS             56..>1092
                     /locus_tag="TVW25_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1379540.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT          344 a          211 c          229 g          308 t
ORIGIN      
        1 aataaatttt aacgcttttt cttgttgtgt atggttatat atgttataat aaactatggc
       61 ttttattaaa acaacaacga ataaagaagg taggacgcat gtctaccttg tagaagggta
      121 tcgtaaagat ggtaaggtca aacagcgtat ccttaaaaaa tttggtctct tagatgagct
      181 tgaattggaa gaaccaggga ttcttgagcg tcttaagcgc gaagctaaag aagatacttt
      241 aaataaccct aaggtactcc aggtttccta tgacctcctt gcccccatga accaaccgga
      301 tcaatcttat ggttggatgg ttttggataa tctcttcgaa tctctggggc tcacagcctt
      361 tttaaagggt atcaaaacga agtctgagta tgacttagtg caagtgctaa agctattagt
      421 ttttcagaga attctccgac cagatagtaa acttgccacc tatgcctctc aagcagactt
      481 atttggccat tgggacatca gcttaaatgc catttatcgc tccttgaaca aattgaacac
      541 cttgaaagat gatcttcaac atcatcttca caaggtagtg agtcagatga tcaaacgtga
      601 agccagtctc gttttctacg atgtcaccaa ttattatttt gagacagata ttccagataa
      661 cgagttggtt tcagaaaatg gagagatact acaagaaggg cttcgaagac gtggtccgag
      721 taaggaacac cgtccaaaac ccattgtgca attaggactc tttagggata ccaacggtat
      781 tccgattagc tataaactgt ttcgaggtaa tcaaaccgat cctgttacct atcttccagc
      841 ggttgaggaa gtcaaaaaac aatttggaat tgagcggtta attgtagtcg ccgataaggc
      901 gatgaatagt atggctaatg tttcagaaat gctcaagcaa gaagatggct ggctcttctc
      961 acagaaacat cgcggacgcc gaggagctcc aaaagatatt caagaacaca tccttgattc
     1021 atcggattgg caatttaacc cagaacttac cttcgctaag aaatcttata tccgtgaacg
     1081 gaagttaggg aa
//
LOCUS       DARYVE010000127         1091 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYVE010000127 DARYVE010000000
VERSION     DARYVE010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..311
                     /locus_tag="TVW25_001962"
     CDS             <1..311
                     /locus_tag="TVW25_001962"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679404.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1379541.1"
                     /translation="IGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKL
                     TIGNERVGLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK
                     "
     gene            397..>1091
                     /locus_tag="TVW25_001963"
     CDS             397..>1091
                     /locus_tag="TVW25_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1379542.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT          381 a          203 c          239 g          268 t
ORIGIN      
        1 ccattggatt ggcctacgga cctggagact tgcgtcgttc actaggtcat attatttctg
       61 tctggggagc tgatcttgac gatcagaatc gcgtggtagc tatttatgta actgattctg
      121 atgataaaaa gttaactata ggaaatgaga gagttggttt gaagcgatat aaagtatcta
      181 gcgatgatca aggtcgtgct cgtctgacga ctcgtgataa agataacaca ggtggtgaaa
      241 ttcgatctat tgaaacatta gatatgggta cacaagagtg ggcagattac ttcaacaaga
      301 cagaaaaata acaataaccc ctacacatat atgattactc cagataaagc acacagcaat
      361 agactcagcc agtaaggaaa ggacgataac aaaacgatgc taacaaacca aacggggtac
      421 aggcatagac ttagtaagca gaagctacct atcagcatgg tttcctgctt gctaggaatg
      481 ggggtgctaa cctctccaac attaatctca gctgatgata gttctcctac tatcatcatt
      541 aaatcgggtg caggtatgac aattgatcct caattaccga aaactctcct ttctaaaccc
      601 gaagagaaac cagaggaaac acctaaactt ccagatgagc gacattatgg tgatgatgtc
      661 agaccggaag aaacaccaaa gcttccagac gagagacatt atggtgacga tataaaaccg
      721 gaagagatgc caaagctccc agatgagcga cattatggtg atgacatcag gaagccgaaa
      781 ccggaggata ctccaaagcc acctaatgaa agcggtcaag gtaatgactt aaaagaagat
      841 ttggagctta aaaagcaacg tcgagagctt acagagcagc ttcgtgcttt aaaaactatt
      901 gaggaagttt tagagttcct gagaaaacca attcctggat ttgtaacaga tgaagattgg
      961 aatttcttag tatcatttgt agaaaaaggc ccagaaaata aaacttttga agtagataaa
     1021 ttaaaattac tagaaatctt ctcaacctca caaggtcata gagtttggtt aggttacctt
     1081 attctggaag a
//
LOCUS       DARYVE010000128         1062 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYVE010000128 DARYVE010000000
VERSION     DARYVE010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..>1062
                     /locus_tag="TVW25_001964"
     CDS             <1..>1062
                     /locus_tag="TVW25_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379543.1"
                     /translation="YHRSSFFIKTGSIVMVLYLAIVSILGLTDYLSMRQYIPTWESSK
                     YYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLDDSGAILFNAPNVRKEGMNDDEE
                     YLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYKIHENEWIVFVPEDVKITELDKE
                     KIHEDHIFQNIKKQGTIIETYVRLKDNQSVFSFDSGKRIDEANLKNYVLVAVNGKELL
                     PDHGIKLSSLVNGQLHPYVKEPSRAYESLKDIIEETESEPFILYISSVYDDIVSRIDE
                     YKMEASIYVIGLVLSIVILATLLKIDKETYFYNHGQRIDVSRLLGYGFFDIHHKKIIG
                     NIVGYIISIIILFMVIMVT"
BASE COUNT          399 a          118 c          196 g          349 t
ORIGIN      
        1 gttatcatag aagttctttt tttataaaaa cagggtcgat tgttatggtt ctttatctag
       61 caattgtaag tattttagga ctcactgatt acttgagtat gagacaatac attccaactt
      121 gggaaagctc aaagtattat gcaaatatgg cttgtgcatg gtcttggagt tatgaaaaag
      181 atgatgataa gttccatgaa attgttattc caaagctgaa taacttatgg aatagtttgg
      241 acgatagtgg agcaatatta tttaatgccc caaacgttag aaaagaggga atgaatgatg
      301 atgaggagta tctaaatcaa caaccttttc aaggtaatta tgcctatgta aataaaaatt
      361 atttacatat tgctaatctc ttagataaag atacgaataa aatagaacaa tataaaatac
      421 atgaaaatga gtggattgtt tttgttccag aagatgttaa aattactgaa cttgacaaag
      481 aaaaaattca cgaagatcat atttttcaaa atataaaaaa acaaggtaca attatagaaa
      541 catatgtaag gctgaaagat aatcaaagtg tattttcttt tgatagtggc aaaagaattg
      601 atgaagcaaa cttgaaaaat tatgttttgg tagcagtaaa tgggaaagaa ttactcccag
      661 atcacggaat caaactatca tctttagtaa atgggcagct acatccatat gttaaagagc
      721 ctagtagggc atacgagagt ttgaaggaca taattgaaga aacagaatct gagccgttta
      781 tactctatat cagctcagtt tacgatgata tagtttcaag aatagacgaa tataagatgg
      841 aggcaagtat atatgttatt ggtctcgtct tatctattgt tattttagca acgttattaa
      901 aaatagataa agaaacatat ttttataatc atggacaacg aatagatgtt tctaggttgt
      961 tgggatatgg attttttgat atacatcata agaaaattat tggaaatatc gttggttata
     1021 tcataagtat tattatttta tttatggtta ttatggtaac ag
//
LOCUS       DARYVE010000129         1043 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYVE010000129 DARYVE010000000
VERSION     DARYVE010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..273
                     /locus_tag="TVW25_001965"
     CDS             <1..273
                     /locus_tag="TVW25_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379544.1"
                     /translation="TIHVLTTSDKVEPDIYKGMLELIAPAKKGQYQEHDVFTVLDDKH
                     EDLAGEGNLVFVYVNEPFEYDKQTLKDLESEDKVTVIKYADLVKQD"
     gene            284..574
                     /locus_tag="TVW25_001966"
     CDS             284..574
                     /locus_tag="TVW25_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379545.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRDREITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            577..756
                     /locus_tag="TVW25_001967"
     CDS             577..756
                     /locus_tag="TVW25_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379546.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVTSTVIM
                     SGIVCVLMNVSDIKE"
     gene            868..>1043
                     /locus_tag="TVW25_001968"
     CDS             868..>1043
                     /locus_tag="TVW25_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1379547.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPYNAL
                     FGIKADSSWTGKSF"
BASE COUNT          331 a          187 c          247 g          278 t
ORIGIN      
        1 actatccacg ttttgacaac cagcgataaa gtcgagcctg acatctacaa aggcatgctt
       61 gagcttattg cgccggccaa aaaagggcaa tatcaagagc atgatgtctt tacggtgcta
      121 gacgacaagc atgaggatct tgcaggcgag ggcaatctcg tctttgtgta tgtcaacgag
      181 ccgtttgagt atgacaaaca aacgctcaaa gacttggagt ctgaggacaa agtcacagtc
      241 attaaatatg cggatttggt aaaacaagat tagaggtggt tagatgatag attttgtaca
      301 aattggtgct ttttgtggcg ctgctttgtc tatcttgggt gtttggggat ttatcgtcaa
      361 tccctttaaa aaagccatgg aagctaacga gctagccatg gcccaactca aagactcgat
      421 caaggagtta gcctacgagc taaaaaatct tgatcgcgat agggagataa ccaaaaagat
      481 tatcgatcgg catgaggagc gtttaggacg tgtagaggac gacattattg tcaataaaga
      541 gcaaatcaaa acattattta aaaaaggaga ctaaaaatgg ataaatggtt taaaaaagta
      601 gcaatcaaaa caattaagac aatggcccaa accgctgtag gggttattgg atcaagcgca
      661 ttgattactg acgtcaactg gcaggtggtg acctcaacag ttattatgtc aggtattgtc
      721 tgcgtcttga tgaatgtgtc tgacatcaag gaatagcatt atgcgagcaa tcacacgatt
      781 agcaatagtc atagcaatca caatactgta tttaccgcta tctgtgattg ctctgattgt
      841 ttatccgttt ttagataagg aggacagatg acctttttag ataagattaa gcaaggctgc
      901 ttagatggct ggaccaagta caaaatcttg ccatctttaa cagcagcaca ggcaatcctt
      961 gagagcggtt ggggtaagta tgccccatat aacgctctat ttggtatcaa ggcagatagc
     1021 tcttggacgg gtaagtcatt taa
//
LOCUS       DARYVE010000130         1030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYVE010000130 DARYVE010000000
VERSION     DARYVE010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            135..1030
                     /locus_tag="TVW25_001969"
                     /pseudo
     CDS             135..1030
                     /locus_tag="TVW25_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          349 a          189 c          220 g          272 t
ORIGIN      
        1 ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt caaatctatg
       61 agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt attgcagaat
      121 ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt gtccaaaaag
      181 gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa gttctgattg
      241 atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct agtatgcttt
      301 caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa agaagaggga
      361 ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca gagttggagc
      421 gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa aagctgagag
      481 aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc aagaattaat
      541 cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt caacctatta
      601 ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg agctcattca
      661 aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc tggaactaag
      721 aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg tcatgggctt
      781 aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg ttggcaaaaa
      841 ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga agtgctatac
      901 cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg ttcttgacgg
      961 ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga agcaagtaca
     1021 aaccatgctt
//
LOCUS       DARYVE010000131         1024 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYVE010000131 DARYVE010000000
VERSION     DARYVE010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            39..>1024
                     /locus_tag="TVW25_001970"
     CDS             39..>1024
                     /locus_tag="TVW25_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379548.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNKYMNSTIVEYISGIEVIKTFNQD
                     SNSYKKYKDAVNLYKDHTLNWFKSTWSIMNFASSILPSTFLGTLPVGMILYLNGTLTP
                     AEFCICLMLSLGIVIPLTQFTNYVNLLKSIEYAVKDINEILCIPNLISIDNN"
BASE COUNT          363 a          125 c          179 g          357 t
ORIGIN      
        1 agtttatgaa ttttagataa aggaggtgga gaagttacat gagcaacaaa aactggataa
       61 atactatatt agattttgct tcagattgta aaggaaagtt gattttatca gtagttatgg
      121 ctagtatagg agtgttcttt agcattatac cttattggtc agtatataaa cttatggcag
      181 tctttataga acaaaaagca actggagaag atgtattgta ttatggagcg attggtatta
      241 ttgcatattt tatcagatat atttgccatg gagtatcaac aatattatct catatatccg
      301 cttacacaat cttaagaaat ataagagaaa atttaggtga aaaattgctc agtatttcta
      361 tgggaaatgc gtcaaaaaag acaataggag aatataagtc aattattgta gacaaagttg
      421 aaacaattga gatgcctcta gcacatatca taccagagtg tgttgctgca ttgcttttat
      481 cactaggtat tgcaatattt atggtcttca taagttggga gatggctctt gcgatgttta
      541 ttacagtgcc ttttgctttg atggcatata aaaaactaat gggtaatttt aatcagcttt
      601 atgaagctca aatgaaatct aacaagtata tgaattctac aatagtagaa tatattagtg
      661 gtatagaagt tataaaaact tttaatcagg atagtaattc atataaaaaa tataaagatg
      721 cagtaaattt atacaaagat catacattga attggtttaa atcaacttgg agtattatga
      781 attttgcaag ttctattttg ccatcaacat ttttgggaac attacctgtg ggtatgattc
      841 tatatttaaa cggaacactg acacctgctg aattttgcat atgtctaatg ctttctcttg
      901 gaatagtaat tcctctcact caatttacaa attatgtcaa tctgttaaaa agtatagagt
      961 acgctgtaaa agatataaat gagattctat gtattcctaa tcttatttct atcgataata
     1021 atga
//
LOCUS       DARYVE010000132         1014 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYVE010000132 DARYVE010000000
VERSION     DARYVE010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..188
                     /locus_tag="TVW25_001971"
     CDS             <1..188
                     /locus_tag="TVW25_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1379549.1"
                     /translation="NWNMVTSKFYRGDLSRRISNNGSGLGLTIVNDIVKHLGGNFEIG
                     EENKRVCAKVILPYRLN"
     gene            466..849
                     /locus_tag="TVW25_001972"
     CDS             466..849
                     /locus_tag="TVW25_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1379550.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
BASE COUNT          369 a          103 c          229 g          313 t
ORIGIN      
        1 tgaattggaa tatggttact tcaaagtttt ataggggaga tttatcaaga cgaataagca
       61 ataatggatc gggacttgga cttacaattg taaatgacat tgtaaaacac ttgggtggaa
      121 attttgaaat tggagaggag aataaaagag tttgtgctaa agtaatactt ccatatagat
      181 taaattaaat cgcaaagaaa acgcaagaat tattcaaaga taccgttaag tataaagcaa
      241 agagctattc tataatgtga gtaaggatag ctcttttata tttgaaagga attattaatt
      301 tgaataagca tctgtgatta taaatatata aaatggaggt ggagttttat gaattacaat
      361 aatcctcata ggtataggaa cggagattga gtagagtttt gggaaacttt attcggaaga
      421 aaaattttac aaaaaattta agtatttgag agaggagaat ttatcatgaa aaaagcattg
      481 tcattagtat tattaacagg tttgatgtta gcatcatctg taccagcatt tgcagcagaa
      541 gaaacaaact tgccatatgt tgaaggtctt ggttatgagg tggaagtatt tgaagaagat
      601 tatactcagc caaagttgtt cagttatgat agcggatgga aaagtttttt aggtggaaaa
      661 tggagacatg gtgtaggtag tcgatatgtt tggtctaaat acgatcacaa taataaaaca
      721 cataaaacta cagtacaagg tgctggtggt caattctctt attcgggttg gacaagcgct
      781 ggaagtagag cagaagcttc ttgggaaaaa gctttaagtg gtaatagggc ttgggctgat
      841 gttaaataac aataaataaa aaatagttga acgagtttga gcggtgccac gttgttattt
      901 tagcattgtg gcattactca tactcgctat ttttataaag ttggagatga tacagaatga
      961 aaaaaacagt gggtatattg gcaattttac taattatagt gattggtata ggaa
//
LOCUS       DARYVE010000133         1001 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYVE010000133 DARYVE010000000
VERSION     DARYVE010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..727
                     /locus_tag="TVW25_001973"
     CDS             <1..727
                     /locus_tag="TVW25_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1379551.1"
                     /translation="FKENKASIENTVVAEQFTGTNYTKDDLTVQVIPDGQEFFYFNEN
                     GSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILASNIIYNSLFSSEAIKKI
                     NDLSASLNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIVFLLIYQYAQMFVA
                     LKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQVELLYIGIASLMVL
                     IFSTIMSFRKLSEKYTQILKGDD"
     gene            727..>1001
                     /locus_tag="TVW25_001974"
     CDS             727..>1001
                     /locus_tag="TVW25_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1379552.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIEN"
BASE COUNT          374 a          129 c          168 g          330 t
ORIGIN      
        1 atttaaagag aataaggcat caatcgagaa tacagttgta gcagaacaat ttactggtac
       61 aaactataca aaagatgacc ttacggtgca agtcattcct gatgggcaag aatttttcta
      121 tttcaatgaa aatggtagta gtgttcctga aaataaagat aatctacctt tggaaagtgt
      181 gacagatagt aaggataata tagtcgttgt gctagatact gataaaatga tagaaaataa
      241 cgattttatt ttggcaagta atataatata taactcactt tttagttcgg aagcaattaa
      301 gaaaatcaac gatttgagtg ctagtttgaa tttttcaatc aatccagtcg aggtttacca
      361 aactgtaaaa cttaatattc aatccttaga gcatcaaatt ttcctttcaa aaatactgca
      421 aataattatt tgtggaatcg tatttctact catttatcag tatgctcaaa tgtttgttgc
      481 cttaaaacag aatgactatg ttaaaaaaat cattttaggc ctatcgaaaa cacgtatagc
      541 catttcaagt ctcaactatt ttattgtgac tattacaatg gttattctat tgacatttat
      601 gttgacagga caagtagagc tattatatat tggcattgct tctttaatgg ttttaatttt
      661 ttcaacaata atgagtttta gaaaattatc tgaaaaatat acacaaattc taaaaggaga
      721 tgactaatgg caattgaagt tttgaatgtt accaaaaaat tcggctcaaa aaagatattc
      781 acagatttaa atttaacgtt tgaagctgga aaaagctacg cattgattgg aggctctggt
      841 tcaggtaaaa gtacactact taatatcata ggaagactag aaaaaattga cagtggaaag
      901 gttttagttg atgagcagga tatttggaag acaaaagaaa gaactttctt taaaactatt
      961 attgggtatg tattccagaa ttattcttta atagaaaaca a
//
LOCUS       DARYVE010000134          995 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYVE010000134 DARYVE010000000
VERSION     DARYVE010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            104..995
                     /locus_tag="TVW25_001975"
                     /pseudo
     CDS             104..995
                     /locus_tag="TVW25_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          354 a          167 c          218 g          256 t
ORIGIN      
        1 aagttacgat gataaattaa gaatatatga actaagaaaa aatgggatgt cttgttcccg
       61 cattggtcaa cagtatgata ttcaggtttc taatctcaaa tacatggtaa agcttatgga
      121 cagatatgga gttgagattg ttagaaaggg taaaaataag tattatcctc cagaattaaa
      181 acaagaaata attgataaag ttcttcttga aggtcagtct caactgtctg tctctcttga
      241 gtatgctctc ccaaatgctg gtatgcttcc caattggata gcgcaataca agaaaaacgg
      301 gtatactatt cttgagaaac aaagagggag accaacgaag atgggccgta aaccaaagaa
      361 aacttgggaa gaaatgacag agctagagcg ccttcaggaa gagctagaat accttagaac
      421 ggagaatgct tatctaaaaa agttgaggga gcttcgttta caggacgaag ccagagaatg
      481 agaaaggcag aaacaattag agagatggtc caagaaggat tccgattaaa cctcctactt
      541 gagatcgcta agatggctcg ttcaacctat tattatcaag tcaagcaatt ggataagtca
      601 gataaagatg aagcaatcaa ctctgaaatc aaagcgattt atgaggagca taagggaaac
      661 tatggttacc gtcgcattca tttagaactc aagaatcgtg ggtttatcgt caatcacaag
      721 aaagtgcaac gcttgatgaa agagatgaga ttagctgctc gaattcgtcg taaacgcagg
      781 tattcctctt acaaaggcga gactggtaag aaggctgata atctgattca acgccagttt
      841 gaagctgcta agccatatga aaaatgttat accgatgtga cagagtttgc tttaccaaac
      901 aacgatgaaa aactttattt agcgcctgtt cttgatggct acaacagtga gattattgat
      961 ttcacactat ctaggtctcc agacttaaaa caggt
//
LOCUS       DARYVE010000135          958 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYVE010000135 DARYVE010000000
VERSION     DARYVE010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..>958
                     /locus_tag="TVW25_001976"
     CDS             <1..>958
                     /locus_tag="TVW25_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1379553.1"
                     /translation="QDNQKVRLASNCLGTTRFNQVMIERGDKATDYVAPVVVEGSGES
                     TGVFKSLEEMLSGLQSINLELTDTKNSNLWSKIKLTTNGMLREYHRDHIKTEIVESAD
                     GIAKRIADDTGQKLALINETIKGIKREYQDADRQLSASYQAGIDGLKTQLANDKIGLQ
                     AEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTEL
                     ESQISGLRSVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQDAEKNYSSLTQTVK
                     GLQSTVSDPSGKIQSRFTQLQNQIDQRVTRDDVMSIINLSGD"
BASE COUNT          308 a          207 c          236 g          207 t
ORIGIN      
        1 gtcaagacaa tcaaaaagtc agattagcca gcaactgtct aggaacaact cgctttaatc
       61 aggttatgat tgagagaggc gacaaagcga ctgactatgt tgcgcctgtt gtcgttgagg
      121 gcagcggtga gtcgacaggt gtgtttaaaa gtcttgagga gatgcttagt ggtctacagt
      181 ctattaattt agagctgaca gataccaaaa actccaatct ttggtcaaaa atcaagctca
      241 cgacaaacgg tatgttacgc gagtatcatc gtgatcatat taaaacagag attgttgaga
      301 gcgcagatgg tattgccaag cggattgccg atgacactgg ccaaaagctg gcactaatca
      361 atgagaccat caaaggtatc aagcgtgagt accaagacgc agatagacag ctatccgcga
      421 gctaccaagc gggcattgat ggcctaaaaa ctcaactggc caatgacaaa atcggtctac
      481 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
      541 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
      601 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcgcact gagttagagt
      661 cgcagattag cgggttaagg tctgtgcagc agtcaactgc aaaacaaatc tcgcaggaga
      721 ttagagacag gacaggtgct gttagtcgtg tgcaacagga cttagccagc tatcaaagac
      781 gcttgcagga cgccgaaaaa aattacagca gtttaaccca gacggttaaa ggtctacaat
      841 caactgttag cgatccgtca ggtaaaatcc agtcgaggtt tacacaacta caaaatcaaa
      901 tcgaccaacg tgtgacaaga gatgacgtta tgtcaatcat caacctatcc ggagatag
//
LOCUS       DARYVE010000136          953 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYVE010000136 DARYVE010000000
VERSION     DARYVE010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..105)
                     /locus_tag="TVW25_001977"
     CDS             complement(<1..105)
                     /locus_tag="TVW25_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1379554.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLL"
     gene            complement(114..>953)
                     /locus_tag="TVW25_001978"
     CDS             complement(114..>953)
                     /locus_tag="TVW25_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1379555.1"
                     /translation="AGGIDAKMSGSEIISAINLNTYGAVIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIKADQIIAGTLDASKARIINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFN
                     IDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAIIREYNSYI
                     NGL"
BASE COUNT          252 a          214 c          201 g          286 t
ORIGIN      
        1 aagcagctta gcgcggccgc gattaactct catgttagta accttaattt tgtctagtac
       61 gctatagagc gtatttaagt ctttgttttg tactgttaaa tccatgttgt ctcctataat
      121 ccattaatat atgagttata ctctctgatg attgcactag tagtgtctga gttaaaggtc
      181 cacgctgtat tattagcgtg tagccagcag cggccaagag ctaaaatggc ctgatacatc
      241 ttattgagat cgaccatttt tggcattagg ctaggccgca tcttaaagcc acgatcgatg
      301 ttaaaatcgt cgctaaagac aatatcatca ccgtaaattt cggcctgatc gacaagcgct
      361 gtgtgctcgt aacctcgcgc atacctaaaa aacctagcac cgcaaaaacg accgctcgac
      421 gcgctgttaa tcccgtcacc tgacgatgtt atcccgatcg aggcgtaaag cgcactacct
      481 gtataatttt ttggcgtggc attgctaaaa tgcacaaagg ctgtgtgggt accgtcttta
      541 cgtaccaaag cgttgtcttt gttattaaag ttaatggtag cgttgctgtt aaagtcaatc
      601 ttagagtttg acaagtcaat catcatcgct ccgttgcgag ctctgataac tttgccctcg
      661 agcaaacttg tgatcgtatg ctcgattttg gccctgataa aattagcatc taagccgaca
      721 atgctgctag cgtttagatt aatgatacga gcctttgagg catctaaagt acctgcgata
      781 atctgatcag ccttgatttt gatagcctcg gctatcttag tggtaaaagt gccattgacc
      841 gttgtattgc catcaagagc gatgtgttta cctgcaatga ctgcgccata cgtattgaga
      901 ttaatcgctg agataatctc gctgccagac attttagcat caatcccacc agc
//
LOCUS       DARYVE010000137          919 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYVE010000137 DARYVE010000000
VERSION     DARYVE010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            20..388
                     /locus_tag="TVW25_001979"
     CDS             20..388
                     /locus_tag="TVW25_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1379556.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
     gene            388..>919
                     /locus_tag="TVW25_001980"
     CDS             388..>919
                     /locus_tag="TVW25_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1379557.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKG"
BASE COUNT          365 a          137 c          171 g          246 t
ORIGIN      
        1 atgaattgga ggttatacta tggcaaacag aacaagaaat aatggaatat accttatgct
       61 ttctgatgat gaacttgaaa ttttgaataa aaaatatgaa ctgtccggtt gtaaaagttt
      121 aagacagttt attatgaagt gcatccttga aaaagatatt tttgtactgg atatgaaagt
      181 gtttaaggag atgtctacaa atatcggaag gattacaggt agcatcaatc agattgcaaa
      241 aagggtaaat tcaactgctg taatttacaa agatgacatc aatgatttga aaaagctctt
      301 ggaaaaacaa ggaaaagaca tctactttct tcgtaaaaag ctatatgaat tagggaattt
      361 tggaacaagt ggtacggagg aaatctaatg gcagttacaa aaattcatcc gatagaaaaa
      421 acactttatc tagcattaga ctatattatg aatgaagata aaaccgatga aaaaatcctt
      481 atctcctctt ttggctgcaa tcccaaaaca gcccatcttg aatttgaaca tacaaaaaaa
      541 gaatgtaatt ccaaagcaaa aatcttggca aggcatctaa ttcaagcctt cgctccagga
      601 gaaactacac ctgagcaggc acaccaaatc ggactggatc tatgtgagag agtcttgagg
      661 ggaaagtatg aatatgtcct tacaacacat atcgacaagg ggcatctaca caatcatatt
      721 ctgtttaaca atgtcagctt tgaaacagga aaggcatatc aaagtaataa gagaagttat
      781 catcaaatcc gaacggtcag tgatgattta tgtagagaaa atggcttgtc agttattgat
      841 gaaaactaca aaaaatttaa aaacagatac tctacaaatg gtaaaaccta tatggaatat
      901 accgaattta agaaaggaa
//
LOCUS       DARYVE010000138          908 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYVE010000138 DARYVE010000000
VERSION     DARYVE010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(7..492)
                     /locus_tag="TVW25_001981"
     CDS             complement(7..492)
                     /locus_tag="TVW25_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1379558.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(581..654)
                     /locus_tag="TVW25_001982"
     tRNA            complement(581..654)
                     /locus_tag="TVW25_001982"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(618..620),aa:Arg,seq:acg)
BASE COUNT          274 a          261 c          137 g          236 t
ORIGIN      
        1 ccccttttat ttctcaccag taaagtcctg aaagtaaggt cctatcttgc gaagcaaggc
       61 ccgtctcccc tcaaaccgct ctcccctgat caaagcccga aactgcgaca gctcaccctc
      121 tgtcaatcgc tcctcaacct ccttcacaat caactgataa gccacataat catctactcc
      181 caaaccacct gctggtatcg catggcctac cgacccaatc tcctcataag ccatcttatg
      241 aaaccgacgc ttctgactct cctgctgccg caacacgtcc ttcaaataag aggaaaactt
      301 ggtcttaaaa taacgatata gcttctcctc atcctctatc aattctggat aagtgaccaa
      361 taaccgatac aagatcaacc gcccctcctg taaccaatca tctagctccc acagctgaat
      421 ataataatgc tgtcttagct tcataataat aggcttgatc ttatcaaaca acctcactaa
      481 atcatcagtc attatacttt ctccttttca tgcttagtag ccttattata aggagacaaa
      541 caaaaaaaca acaggacaga aatgtcctgt tgccttgcta tgcaccctag aggagtcgaa
      601 cctctaaccg cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgcttttct
      661 taactattac tatcctacca tactatcccc taaaaagcaa ggctctatac catctggaat
      721 aggtaagtcc actgtggaaa tcatagagct ttttgagtac acaaaaaaga gagcaccaaa
      781 ctgatcctct ctaaatgtcc gttgttagtc aacccactat agttgacata gagccaaact
      841 ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
      901 agctatgg
//
LOCUS       DARYVE010000139          902 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYVE010000139 DARYVE010000000
VERSION     DARYVE010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..317
                     /locus_tag="TVW25_001983"
     CDS             <1..317
                     /locus_tag="TVW25_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEL1379559.1"
                     /translation="RGDVLLRKFKAESNKINGQIKTIKNELKVVDDKKRSIKRRKDEL
                     KKFIEALFYCLEDYKSIEVDKELVDTLINRIEISKYKQVTIYFKFSFDKDIEKQLEVE
                     HE"
     gene            310..>902
                     /locus_tag="TVW25_001984"
     CDS             310..>902
                     /locus_tag="TVW25_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1379560.1"
                     /translation="MNRIAIYLRLSEEDYKKTDESVSIVNQRDYVRNYIENENSLKDC
                     EIEEYIDDGFSATNTNRPSFLRLIDNIKAGRINTIIVKDMSRFSRDYILLGDYLSNIL
                     PFLKIRFIAINDNYDSINEDGNGIDTDIQFKTLYYDLFSKELSEKVKSSFKQLKSQGK
                     NTNWAAPFGYIKDPKDKHHIILDEKTAFIVKEAFDLL"
BASE COUNT          379 a           93 c          172 g          258 t
ORIGIN      
        1 ttagaggaga tgttctttta aggaaattta aagcagaaag taataaaata aatggacaga
       61 taaaaacgat aaaaaatgaa ttaaaggtag tagacgataa aaagaggagc ataaagagaa
      121 gaaaagatga actcaaaaaa ttcatagaag ccctatttta ctgcttagag gattacaaga
      181 gtatagaggt ggataaagaa ctggttgata ccttaattaa ccgtatagaa atctcaaaat
      241 acaagcaagt aactatatac tttaaattta gttttgataa agatatagaa aagcagttgg
      301 aggtagagca tgaatagaat agccatttat ttaagacttt cagaagaaga ttataaaaaa
      361 acggatgaaa gtgtaagtat agtaaatcag agagactatg taagaaatta cattgaaaat
      421 gagaactctc tgaaggattg tgagatagaa gaatatatag atgatggttt ttctgctaca
      481 aatacaaaca gaccttcgtt tttaagactt attgataata taaaagctgg gagaataaat
      541 acgataattg taaaggatat gtcgagattt tcaagagatt atatattgct tggagactat
      601 ctgagtaata tattgccctt tttgaaaata cggtttattg ctatcaatga taactatgat
      661 tcgataaacg aagatggaaa cgggatagat acagatatac agtttaagac cttgtattat
      721 gatttattca gtaaggaatt atcggaaaaa gtaaaaagtt cttttaaaca actcaaatca
      781 cagggcaaga atacaaattg ggcagcacct tttggatata taaaagatcc aaaagataaa
      841 catcatatta tacttgatga aaagacagct tttatagtga aagaagcttt tgacttgctg
      901 tt
//
LOCUS       DARYVE010000140          882 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYVE010000140 DARYVE010000000
VERSION     DARYVE010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            64..651
                     /locus_tag="TVW25_001985"
     CDS             64..651
                     /locus_tag="TVW25_001985"
                     /inference="COORDINATES: protein motif:HMM:TIGR02185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1379561.1"
                     /translation="MSNKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLI
                     ALFTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRA
                     ITRYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSP
                     AILIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
BASE COUNT          293 a          102 c          161 g          326 t
ORIGIN      
        1 aagtaaaaaa agaattaatt aaagaatttt tattaaaaac tacgatgaca gaggagaata
       61 ataatgagca ataagttaaa aggaaaagat ttaataacaa taggcattta tacagcaatt
      121 tattttgtaa taaattttgc atttatgcta gctggaatga taccagttat gtggattatg
      181 atgccttcac tgatagcttt atttacaggg gtgccataca tgatgatttg caacaaagtt
      241 caaaaagctg gtgctatttt aatcatggga acagttacag ttttgatata ttatgcaaca
      301 ggacaattta caacagttat tcttgcaact tttgcagtag gttgtatatt agctgaaatt
      361 attagagcaa ttactagata tacaagtttt atagggaata ctttatcatt tgcactattt
      421 tcaattggaa tgataggatc gcctcttcct atttggttgt ttaaagaatc attttttgct
      481 catatatcag aggttggtat gtcgcaggat tacataaatg ccttggaaaa gtttacttcg
      541 ccagcgattt tgataggagt tattattttg acttttattt gttcgttagt tggggctttg
      601 attgcgaaaa gaatgatgaa taaacatttt aaaaaagcgg gaattatata aaatgcgtga
      661 atatagatta aaaatagatc cgagagcagg gatttccctg ctttttatct taaactttac
      721 gatatttaat gtatccacag tttatgcatt atttgtgcta ttaatttgga actgtgttta
      781 tgcaatgtgt aatggatatt gtaggatagc aatcaaattc atttttactt attggttgct
      841 ttatttgata gaatttttgg ttttaccgaa actaccaagt tt
//
LOCUS       DARYVE010000141          869 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYVE010000141 DARYVE010000000
VERSION     DARYVE010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
BASE COUNT          353 a          153 c          123 g          240 t
ORIGIN      
        1 gaatattagt aacttaatta aagataaaaa aaccgaaata aatgcaaaaa ccaagacaaa
       61 aatcgccaca tgatactact gtcaacttaa agactattct ttgaaaaatt atctttataa
      121 attcattatt tttaataaaa ataagacaaa agatgagaaa aatagccaaa aagctactaa
      181 tctcagcagc cttgcaaact ggcagcgaca ttataggtaa aatgataacg ctgagaaaca
      241 agcccttctc tttttataca tattatacat aatccctaca ataacagtag ttatggtttt
      301 acatcgtcaa atcattagag aaaccatata tgctaaactg tcatagcctc cactactctc
      361 taggagatga tagagatgac ccgcttagta acaagcctaa aagtatcttg caatagcttc
      421 taaagctttg cttgcagtaa aaaaggtgag cgttctagcc taaatgcttg tcacacataa
      481 gcaagcctca gacagcctca aaataagctt ttccatagca agtctgtcac gctggacggg
      541 ataggggtct tatatctcat taatatataa aataaatctc tcggccacat aatacattgt
      601 tacctacaga cgaattcctc aatttagata acctaagttc ttcttccctt taatcaacaa
      661 catataaact aagcttaaaa actacaataa agaaatacag caaaagataa tttttcaaat
      721 aaaatattgg aacttcaaca tgaatatgct ataatgaaac aactaaagga tgattaagga
      781 tgtagaatga gatatattgg ttctaaaaaa ttattgttga cagaaattaa gaccatgcta
      841 gacaaacata aaactggtga tgaagaagt
//
LOCUS       DARYVE010000142          860 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYVE010000142 DARYVE010000000
VERSION     DARYVE010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..860
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..779
                     /locus_tag="TVW25_001986"
     CDS             <1..779
                     /locus_tag="TVW25_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1379562.1"
                     /translation="KLVSSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLKFKPAAT
                     VAYSSSTGGAVNIDLSSSRGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYKGT
                     TNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEASYD
                     ENAAALSIDIVKKANGVGTAAQGIYINSTSGTTGKMLRIRNLNDDKFYVKPDGGFYAK
                     ETSQIDGNLKLKDPIANDHAATKAYVDGEIKKIKALLTAK"
BASE COUNT          291 a          169 c          197 g          203 t
ORIGIN      
        1 ccaaattagt atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
       61 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctaaaattta
      121 agccagccgc cactgttgct tattcctcgt caacgggtgg agcggtcaat attgacttgt
      181 cgtctagcag aggtgctggt gttgttgtct attctaacaa tgataccagt gatgggccgt
      241 taatgagctt gcggacgggt aaagagacct tcaatcaatc ggcgcttttt gtcgattata
      301 agggaacaac aaatgccgtt aatattgcga tgcgtcagcc aaccaccccc aatttttcat
      361 cggcgcttaa tattactagc ggcaatgaaa atggtagtgc gatgcaaatt agaggcgttg
      421 aaaaagcatt gggaacgctc aaaatcacgc acgaaaaccc aaacgttgag gcaagttacg
      481 atgaaaacgc tgcagcgtta tctattgata ttgtcaaaaa ggcaaacggt gtaggaacag
      541 ccgctcaggg aatctacatt aactcaacct caggcacaac tggtaaaatg ctcagaatca
      601 gaaaccttaa tgatgataag ttctacgtca agcctgacgg tggtttttat gccaaggaaa
      661 cttcgcagat tgatggcaac ctgaaactca aggatcccat agcgaatgat catgcggcaa
      721 ccaaagctta tgttgatggt gaaatcaaaa aaataaaagc actcttaacg gctaagtaaa
      781 tgtaaaaagg aggagatatg agcagagacc caacattaac attagacgag tcaaatttaa
      841 cgatcggctc agatggacgt
//
LOCUS       DARYVE010000143          854 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYVE010000143 DARYVE010000000
VERSION     DARYVE010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..782
                     /locus_tag="TVW25_001987"
     CDS             <1..782
                     /locus_tag="TVW25_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1379563.1"
                     /translation="KLASSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLRLKPNSG
                     IKHSSSVGGAINIDMSKSTGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGK
                     TNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRGIEKALGTLKITHENPSLGADYD
                     ENAAALSIDIVKKANGAGTAAQGIYINSTSGTTGKLLRIRNENKDKFYVNPDGGFWSC
                     ANSTVAGNLTVNDPTSEKHAATKKYVDEKIAELKKLIQKTD"
BASE COUNT          312 a          157 c          182 g          203 t
ORIGIN      
        1 ccaaattagc atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
       61 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctacggctta
      121 aacctaatag tggtattaag cactcatctt ccgtaggagg agcgattaac attgatatgt
      181 ctaaatcaac aggtgctgct atggtgatgt atacaaataa agatactact gatggaccat
      241 tgatgatttt acgctctgac aaagatacgt ttgatcagtc agctcaattt gtggattaca
      301 gcggtaagac taatgctgta aatattgtaa tgcgccagcc aagcgcacct aatttttcct
      361 cggcacttaa tataaccagt gccaacgaag gcggtagtgc gatgcaaatt agaggcatcg
      421 aaaaagcatt gggaacgctc aaaattactc atgagaaccc aagtcttgga gcggattatg
      481 atgaaaacgc tgcagcgtta tctattgata ttgtcaaaaa ggcaaacggt gcaggaacag
      541 ccgctcaggg aatctacatt aactcaacct caggcacaac agggaagttg cttagaatta
      601 gaaacgaaaa taaagacaaa ttttatgtaa atccagatgg tggcttttgg tcatgtgcaa
      661 attcgactgt agctggtaat ctaacagtta acgatccaac atctgaaaaa catgctgcga
      721 ctaaaaaata cgtagacgaa aaaattgctg agttaaaaaa acttatacaa aaaacagatt
      781 aaggaggata aatgagtaga gatccaacac taacattaga cgagtcaaaa ctcgtcatag
      841 gaccagacgg ccgc
//
LOCUS       DARYVE010000144          846 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYVE010000144 DARYVE010000000
VERSION     DARYVE010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(107..622)
                     /locus_tag="TVW25_001988"
     CDS             complement(107..622)
                     /locus_tag="TVW25_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379564.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
BASE COUNT          261 a          150 c          137 g          298 t
ORIGIN      
        1 tacatgtgtg tgaaacacaa aaaaccgccc agaaataatc tgagcggttg atttttattt
       61 tggctaattc ttactatggt aattggttca tgattgtgcg agggtgtcaa cgaagataat
      121 cggcatcggt aatgcttttt aatctgtcgg tatagtttgg gaatgtagag aatttgaaac
      181 gtttaggatc tgttaattta tgttgatcac tattagctac agcttgatta taatctatga
      241 tagcctttat caacttgtta acaataagta tatcattatc aacaatctta aaataatcaa
      301 cctgctctcg taatttgaac gttctgttta aaatatattt tggatcttca accactagag
      361 ctttgccaat atcaagcccc tctacgcatc cgtatttttt agagtctctt aatttatatt
      421 ttagttgata ttttttagga atattacttc tcaaagggat tgcaaaagtt agattttgga
      481 tacttaccaa cacaatggca aaacctcggc ctttgttata tagcttcttc tctttaaaat
      541 catagtctaa agcttgtacc aaatcgaaat ctcgacacat gtttaaatca atctgaccga
      601 atactaattt tttactcttc attatttgcc ttctaaaaat aaaaaatcct accaactggg
      661 tattggtagg acgcattgcc aacgggatac ttctgttaac gagcgcgtcc ctccgccccc
      721 tcattgccaa aatggcgaga gtttaacgac atggaaaggt cggaacatag agataatgct
      781 tttactattt atgttcattt acattattac ataatatgtt gcattcgtca aatatagaat
      841 ctttaa
//
LOCUS       DARYVE010000145          836 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYVE010000145 DARYVE010000000
VERSION     DARYVE010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..221)
                     /locus_tag="TVW25_001989"
     CDS             complement(<1..221)
                     /locus_tag="TVW25_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379565.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRG"
     gene            complement(241..633)
                     /locus_tag="TVW25_001990"
     CDS             complement(241..633)
                     /locus_tag="TVW25_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379566.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            complement(630..>836)
                     /locus_tag="TVW25_001991"
     CDS             complement(630..>836)
                     /locus_tag="TVW25_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379567.1"
                     /translation="LSWAELEEAYAQAGVTYDSLVGQTKRHFDDKVTQARGLATKFKT
                     VKEQLEEGVERTAAIDQKLGCDFS"
BASE COUNT          165 a          228 c          180 g          263 t
ORIGIN      
        1 tgccctctaa tgctgctatc tagctgattg acaatggtct gaatatgatc tgcggtgtct
       61 gtggcaatcc gagatacctc actgtcatag cgcctttgaa gggcatgaag gcgacctaag
      121 gtcaagggag cacatatgga ctgaactaat ctcctatcca gctctttctt taaagtcctg
      181 atcggctctt gtccggttaa gatcatctct atagcaatca tctttcttat ctccttttcc
      241 ttaaccttca cgccactgac gcctcagcgc tgtgatgtcc ttttctatcg cctgtcgctg
      301 gctgcgatag tgatggtcaa ttgcttcctc ctgctgcgac atcttgcgac cttgctcatg
      361 atagcactgc tctgttcggt gctggtagtc atcaatcagc ctcgttagaa cggtatattg
      421 gtctgttatc agactagcat cataatgtct gaggtagctg ctaacggcct gatagctaga
      481 ggcatagagc tgctgtagct ggttatagtt gcctcttaac tcgtcatggg ctgctgccat
      541 ttggagccgc tcttgatgat agtgctcctg ctgctcctct agctcctctt ccttttgacg
      601 gatagcagtt ctgatctttt ctaatgctgt catgaaaagt cgcatcctag cttttgatca
      661 atagcagctg ttctctcaac cccctcctct agctgctcct ttacggtctt gaactttgtg
      721 gccagtcctc tagcttgagt aaccttgtca tcaaaatgcc tcttggtctg acccacaagg
      781 ctgtcatagg tcactcctgc ctgggcataa gcctcctcta gctccgccca gctcaa
//
LOCUS       DARYVE010000146          806 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYVE010000146 DARYVE010000000
VERSION     DARYVE010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            65..655
                     /locus_tag="TVW25_001992"
     CDS             65..655
                     /locus_tag="TVW25_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379568.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT          279 a          143 c          146 g          238 t
ORIGIN      
        1 tagaaaggag taaagctaat taacccttag tagatcacca tcgttttcag aaaggaaatt
       61 caaaatgaaa aaagtaaaac aattgatcat cgcaatgata gcgtccttat tactcattgc
      121 taacactgta ccttccattg tatatgctag tgaagtgact aaaattcaac aggaagaaaa
      181 agtaattgaa gaaaaattat cacaacctct agaaatttca aaaagtgagt tagatacatt
      241 aatccaagag aaaaaagctc tttatccaaa tttaacagaa caagaaatgc gtgaaattgc
      301 gtataaagcc atgagtccat acacttttag agctagtgta tgggacgggc aaggagtaac
      361 cttagatgaa ttcgcttggg cttttgatgt tattgtaggc gggttaatta gtggatatgc
      421 aaccatcgga aagtacgttg ccaaacatgg agtagctgcc gctcgagctg tacttagccg
      481 agctgcaaaa gctgcagctc aacgacttgg tgtactaacc ggatttattt ccggtttact
      541 tagagctgca ttctcagtaa taaacattta ctataatgtc ggatatgccc tagcacaata
      601 tgtcgatgct cgagattatc acccaaataa cggtcgtata aatgcgtggg cttaagaact
      661 atatttgtta ttttattatt gtaatgtcag tttatacagc aatagcatat tgtttcaatc
      721 gcttatcctt atcatttact ccaaaactag ttttctattc ggccataacc acctatactt
      781 tttacataac aaaaaataaa gactga
//
LOCUS       DARYVE010000147          800 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYVE010000147 DARYVE010000000
VERSION     DARYVE010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(290..>800)
                     /locus_tag="TVW25_001993"
     CDS             complement(290..>800)
                     /locus_tag="TVW25_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1379569.1"
                     /translation="GPSGVGKTTLAKLILNYYPKHLYDGEIRIDGRNIAEINSESLYK
                     KIAFVQKNDFLVEGNVSDNIKLDGSLNLTDKLKDSLGFDETFLNKKLFRVQSLISEGE
                     KQRIDLARFLNRRYSIYIFDEPTGNLDPARSKAILDYILSIKNAIIIVITHNQDIKTL
                     EQFDEVICL"
BASE COUNT          255 a          152 c           84 g          309 t
ORIGIN      
        1 ctgaccaaaa aattgagttt cctttgattt ctagaacatc attatcatca gctcctatcc
       61 ttaatttatc attttgccat gaatatacaa tcctatcctg attccatttt ggaaaaaaat
      121 tattcatttt attgtccttt ctatatttta caaaggcatg caaattctca ttgcatgcct
      181 ttgtgattaa acaaaatacc aatttgtggt ttgttcattt cgaacttcga caaactctag
      241 ttctaaaact tcaaaatctt ccataatcat gttcatcacc ccctttcatt tacaaacaaa
      301 tgacttcatc gaattgttct aacgttttta tatcttggtt gtgagtaatc acaatgatga
      361 ttgcattctt tattgataaa atataatcca atatggcttt agatctagct ggatcaagat
      421 taccagttgg ttcatcaaaa atataaatag aatatctacg gtttaaaaat cttgctaaat
      481 caattctttg tttttctcct tctgagatta aagactgaac tctaaataat tttttgttta
      541 aaaatgtttc atcaaatcct aaactatctt tgagcttgtc tgttagattc aaactcccat
      601 ctaatttaat attgtctgaa acattacctt ccacaagaaa atcatttttt tgaacaaacg
      661 caatcttctt atacaaactt tctgagttaa tttcagcaat atttcttcca tcaattctta
      721 tttccccatc atataaatgc tttggataat aatttaatat cagttttgct aatgttgttt
      781 tcccaacccc cgaaggacca
//
LOCUS       DARYVE010000148          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYVE010000148 DARYVE010000000
VERSION     DARYVE010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TVW25_001994"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TVW25_001994"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1379570.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYVE010000149          748 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.150, whole genome shotgun sequence.
ACCESSION   DARYVE010000149 DARYVE010000000
VERSION     DARYVE010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.150"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..691)
                     /locus_tag="TVW25_001995"
     CDS             complement(<1..691)
                     /locus_tag="TVW25_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1379571.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNT"
BASE COUNT          231 a          160 c           87 g          270 t
ORIGIN      
        1 atgtatttac aaacatatgc ttgccattaa tatatctgta agagaattct ttcgtcgtat
       61 aatcttgcca ttttaaaagt tcttcaagtt ccatttcttc atcaatatca cccatcagac
      121 ctaaaatctt gctattcaat ttttcccctt ttgtatcctg gtagtcctca tcgataataa
      181 aatcggctct tagtgttggt aaaaaaatcc caatcaaatc tttattgtct aatatctcat
      241 ttggagtacc atcatatctt cttaaccctt caataaatcc ttcatcatct aaatgataaa
      301 tcggattcgg ttccttatag caaggggctc gcccagctga tatgataatt ccattcggat
      361 ttggtaaccc attttcttta attttcagag ccaattcata agcaatctta gttcccatac
      421 tatgcccgaa aaaataataa ggtgagttaa aatcaaaagt catttttaag tcttcaaaca
      481 atccttttac aagttcttct atgttgctaa ttgctttttc agaaaacctg ttttctctcc
      541 ctggatactg tgcaacgaag agatttatat ctttaaattg attaccccat cttctgaatg
      601 atgatactcc accacctgca aatggaaaca caaataaact agctttcgtg ttttccattt
      661 ctttattaac gtattcgaac cacattccca tcaaaacacc ttccatctga ttattaatat
      721 actactagaa ctattattgt tagataca
//
LOCUS       DARYVE010000150          702 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYVE010000150 DARYVE010000000
VERSION     DARYVE010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(15..>702)
                     /locus_tag="TVW25_001996"
     CDS             complement(15..>702)
                     /locus_tag="TVW25_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1379572.1"
                     /translation="IKDVSFEIKENTVTAIIGPSGSGKTTICNLISRFYDVSGGSIKI
                     GNVNIKNLTLSSLLSNISTVFQKVYLFNDTIENNIKFGNPNVSKEEIINAAKKSHCHE
                     FIMNLPNGYETIVGEGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPENEYLI
                     QRAISNLSKGKTVIIIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLYRDYMR
                     IRGKTEDWKI"
BASE COUNT          205 a          145 c           69 g          283 t
ORIGIN      
        1 tcctcctatc tatattatat tttccagtcc tctgttttac ccctgattct catataatct
       61 ctatacagac catcttggct catcagttct gtatgctttc ctatttgagc aatctctcct
      121 tctttcaaaa caattatctg atctgcttct tcaattgtta caattctatg agcaataata
      181 attacagtct tacctttact caaattcgat attgctcttt gaattaaata ttcgttttca
      241 ggatctatgc ttgatgttgc ttcatccaaa ataataattg gagcatcttt tagcattgcc
      301 cttgctatag atattctttg tttttctcca ccagataaaa aatcaccacc ttcaccaaca
      361 atagtttcat atccatttgg caaattcatt ataaattcat gacaatgtga cttcttcgct
      421 gcatttatta tttcttcctt acttacattc ggattaccaa attttatatt gttttcgatt
      481 gtatcattaa acaaatacac cttttgaaat actgtactta tatttgaaag taaacttgat
      541 aaagtcaaat tttttatatt tacatttcca atttttatac tcccaccact tacatcataa
      601 aaacgagaaa tgagattaca aattgttgtt ttacctgacc ctgatggtcc tataatagct
      661 gttaccgtat tttcctttat ctcaaatgaa acatccttta ta
//
LOCUS       DARYVE010000151          678 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYVE010000151 DARYVE010000000
VERSION     DARYVE010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..>678
                     /locus_tag="TVW25_001997"
     CDS             <1..>678
                     /locus_tag="TVW25_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1379573.1"
                     /translation="KSVVGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWD
                     KEALKTNKEVTMTTANEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDL
                     WGNAIDLLNSAAAQGLEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIK
                     TVEQNIDGNWDSLQVGGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETS
                     KTGTFTLD"
BASE COUNT          201 a          128 c          175 g          174 t
ORIGIN      
        1 aaatcagttg tcggggagac tgactataaa aaggcttgtc atgcaataaa agcagccggt
       61 tatgccactg caagtgatta tgcggagctg cttatccagt tgattgagga aaacaacttg
      121 caaaaatggg ataaggaagc cttaaaaact aataaggagg taacgatgac aaccgcaaat
      181 gagattgtac aatactgtgt tgaccttgcc aactcaggta tgggagttga taaagatggc
      241 tgttttggga cgcagtgtgc ggacttgcca tgttttatcg tcaaaaactg gttcgggatt
      301 gacttatggg ggaatgcgat tgacctgtta aacagtgcag cagcgcaagg tctagaggtt
      361 atctataacg cacctggagt taatccaaaa gctagtgact tatttgtcat ggaggtagct
      421 ggcagtcctt atggacacac aggagctgtt attgaggaca gtgatggcta taccattaaa
      481 actgttgagc aaaacattga cggcaactgg gacagtttac aagtaggtgg ccctgctcgc
      541 tttaatactc gtgactttac tggcgttgtc ggctggatta ggttacctgt tgaccatact
      601 aaccagacag tagatacagc accgcaaacg tctgacacca tcgtggagac gtcaaaaacg
      661 ggtactttta cacttgac
//
LOCUS       DARYVE010000152          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYVE010000152 DARYVE010000000
VERSION     DARYVE010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..>672)
                     /locus_tag="TVW25_001998"
     CDS             complement(<1..>672)
                     /locus_tag="TVW25_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1379574.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALA"
BASE COUNT          140 a          183 c          152 g          197 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ct
//
LOCUS       DARYVE010000153          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.154, whole genome shotgun sequence.
ACCESSION   DARYVE010000153 DARYVE010000000
VERSION     DARYVE010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.154"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            1..672
                     /locus_tag="TVW25_001999"
                     /pseudo
     CDS             1..672
                     /locus_tag="TVW25_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          235 a           81 c          136 g          220 t
ORIGIN      
        1 ttgagtcgtt agaaacatat tatgctagtg aaggaattgg tgggattaaa ctattaaaaa
       61 tgttagggaa tctaaagatt tctattctgg gatgtggtgg tggtggatct catattgcat
      121 tacaattagc tcaattagga gtgggaagaa ttcatttggt ggattacgat attgttgaag
      181 aaaacaatat caacagacaa tccatgttca catttaacga tgtcggaaat tacaaagttg
      241 attgtgtagc caaaaatatt cagcaaagaa attctaaatg tttggttacc aaaagcactt
      301 ctaaaatgat taatgtacct gatgtaaaaa aaagaaatat ctgaaagcga ttgggtattc
      361 tgttgcatgg atgaacctcc ttatatagca cagaggattg taaatagagc atgttattta
      421 ttaaaaattc caagtatata ctgttttagc caacgtagtg cggggaaact tttgttttgt
      481 aatcctaata ttgaagattc tggctgtatt gattgtttgt tatctgaaca agataatgaa
      541 aactttcaaa agctggtgac aacgttcact acctataata ggaaattggt aactgcaaat
      601 atcttaccaa atattttatt attgacatcg tgggtggtta aacgatggtt agattgtgta
      661 acagataaaa at
//
LOCUS       DARYVE010000154          671 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.155, whole genome shotgun sequence.
ACCESSION   DARYVE010000154 DARYVE010000000
VERSION     DARYVE010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.155"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(332..562)
                     /locus_tag="TVW25_002000"
     CDS             complement(332..562)
                     /locus_tag="TVW25_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379575.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
BASE COUNT          130 a          136 c           90 g          315 t
ORIGIN      
        1 cttgcttctt tgtctgtgtt aatcgctttt cttgttttta taactgctct atacaagtct
       61 taactttttc tgcctgttta attttttctc gtatctctaa tattttattg tgtaagctct
      121 ttttttcttt cttcatattg gcgacttccg attttcattt gctaatgact aaggtcttgc
      181 tttcgcccaa atgctctttt agatatttct tggcactctc aaataaaata atctctgctg
      241 tatcaacgtt agctgatatg ccctctgcaa gagccttcgg agaacgcacg cacctgttga
      301 ggtgtatatg tacactcttg taaacaaggg actattcctc tgtgtccgtt gcttcctctt
      361 gcacttctat gttttcttct gtttgttctc ttttctctat gatttttagg attttttgat
      421 tgactgctcc cttttcataa aggcgtctat ctctcttttt tctctcttcc tgtttcgact
      481 gaatgatggg cttttttctt ttgttttgta actgcttgat ttctccatct gtcattaaaa
      541 ttttttcatc tatgtttttc attttctatt ttcctctctt tctgttttga gcaacaaaaa
      601 aacagtaaac catttttttg atttactgtt ttctaataaa tattatctta gttatctatt
      661 ctacttttcg t
//
LOCUS       DARYVE010000155          667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.156, whole genome shotgun sequence.
ACCESSION   DARYVE010000155 DARYVE010000000
VERSION     DARYVE010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.156"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(92..562)
                     /locus_tag="TVW25_002001"
     CDS             complement(92..562)
                     /locus_tag="TVW25_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1379576.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
BASE COUNT          188 a          126 c          142 g          211 t
ORIGIN      
        1 tcaaggcttt tgcaggagat ttatgaaaaa gaaaaattta ggatagtgta agtataagct
       61 agtttcctta agaaaagctt aactgaagca attaatcgta gagatgggtg attgttttga
      121 cgactttttt ctccttgtca gaccaataat gaaggcgttc aaaagatcct tgtcgccagt
      181 agagtggtag cctttgtcga atatcctctt gcatgtctag cttatctaga tcagcaatag
      241 catgccattg tggtaggccc tctcgtgatt tagttagcag cttgccttca aaatcttcgc
      301 aaagaaagtc ataataaaca tagcgctcag gcttatcagg attggtaaag cctgagattc
      361 cctttaattg cagatttaag gcggttaagc cggtctcctc ctttagctca cgcactgccg
      421 cttcaaaaaa ggattctgag gtgttaacct tgccacccgg ttggatccag ccaggaaaat
      481 cgtcatgctg gcggttgaga agtaggatct tgtcgccctc cttgacacag atattaaccc
      541 aatttttgat gacttcaagc attagttacc tcgtttttag ttttatttta tcaaaaaaag
      601 atcagtatga atagctgaga gatttattga tatggtcata atggcttcag atagttttac
      661 tgctgct
//
LOCUS       DARYVE010000156          634 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.157, whole genome shotgun sequence.
ACCESSION   DARYVE010000156 DARYVE010000000
VERSION     DARYVE010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.157"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..>634)
                     /locus_tag="TVW25_002002"
     CDS             complement(<1..>634)
                     /locus_tag="TVW25_002002"
                     /inference="COORDINATES: protein motif:HMM:NF012873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379577.1"
                     /translation="DFWERRIPFLPDAPLLPIKNKIVKNGFERIQLRIDENTWSKIKS
                     NISEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYIKSDVVNDFTSTELL
                     EFRMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVERRDAIFPFVFTSAL
                     GIKASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRADAFSKE"
BASE COUNT          202 a          111 c           78 g          243 t
ORIGIN      
        1 aattcttttg aaaaagcatc tgctcttaag tcaaaattaa ttattagttc atgatttacc
       61 tccattactt gacaatccat taatacttga ggagtttcac tcaaaccttc tttttgtaaa
      121 ctaatatatt tatattctga agcttttatt cctaatgcac ttgtgaaaac aaatggaaat
      181 atagcatctc tcctttctac atttttccta acttcacgag taacttccac tcctgtaaat
      241 gtttcatgtt gcaaatcttc aatcatttgc tgttgtatgt gttttaataa aacatagaat
      301 ggttgcagag attccattct aaactctaaa agttctgtag atgtaaaatc attaacaaca
      361 tcgctcttta tatactcctt tggtctattc atagttgtta aattaatggt aaattcagaa
      421 ttagaactcc atctattaag aacaagagct aatattgtca ccaagaaaga tgtttgcgtg
      481 acaccaatct cacttatatt agattttatc ttcgaccaag tattttcatc tattctaagt
      541 tgtattcttt caaaaccatt tttgactatt ttatttttaa ttggtaatag tggagcgtca
      601 ggcaaaaaag gaattcttct ttcccagaaa tctt
//
LOCUS       DARYVE010000157          618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.158, whole genome shotgun sequence.
ACCESSION   DARYVE010000157 DARYVE010000000
VERSION     DARYVE010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.158"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            185..>618
                     /locus_tag="TVW25_002003"
     CDS             185..>618
                     /locus_tag="TVW25_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1379578.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKG"
BASE COUNT          244 a          110 c          149 g          115 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaaggg
//
LOCUS       DARYVE010000158          613 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.159, whole genome shotgun sequence.
ACCESSION   DARYVE010000158 DARYVE010000000
VERSION     DARYVE010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..613
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.159"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..588
                     /locus_tag="TVW25_002004"
     CDS             <1..588
                     /locus_tag="TVW25_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1379579.1"
                     /translation="EKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKEDNNTTSEK
                     SNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNVKYTNCLAY
                     NDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQSKTNQNAKD
                     VKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT          277 a           62 c          131 g          143 t
ORIGIN      
        1 gaaaaatttt atcattatat agatgaaaat gagattgaag cacctgattt agaaagcgaa
       61 atacaggata agaatagtgt tttatccgat gaggaaaatg taaaggagga caataatact
      121 acgagtgaga agtcaaatga aaataaggaa aaagcaaata ctgtaaatat caatggcaat
      181 attgcttcag atatagacat taaaaatttg acatcgaaag atggtagaga ttttactgtt
      241 gcaagttttg cagttgctga aaatgacaag gagggaaatg taaaatatac caactgttta
      301 gcctataacg ataaggtaag tagtgtagaa aatttgaaaa aaggagattt tgttcatgta
      361 ttcggaaaag aaaaaatcag tcagggaaag gacggaaagg aatatacatc tcttaaagtt
      421 tattctgcaa agctgttaaa agccaaagaa cagagcaaaa caaatcaaaa tgcaaaggat
      481 gtaaagaaac cgtcagcact tggcaagtta aaagagtata aggaaaaggc aggcgaaaaa
      541 tcaaaggaac aggtcagtgt caaaaaagat aaaaatatag agagataaaa ttataaaaat
      601 agtgggtaaa tag
//
LOCUS       DARYVE010000159          608 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.160, whole genome shotgun sequence.
ACCESSION   DARYVE010000159 DARYVE010000000
VERSION     DARYVE010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.160"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..>608)
                     /locus_tag="TVW25_002005"
     CDS             complement(<1..>608)
                     /locus_tag="TVW25_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379580.1"
                     /translation="TDGLRLDEYNPFEDDENISDLIRLTFFQNNDGEYRVVYNNADSL
                     LYSSNVDYFLEKIEAEKVRLEDNIAEIPNEDKIAVKVGNYYAVVEKERVKDISLEETG
                     VRVYPKENNFEGKIYPLYRGSTFEESAKIDKLFDEIAIGMKEVNLTDLNDVFYLENQG
                     LYEISSDRVTEEKAGYDFEVASFNEQFPDYYNDIYVYNRNLK"
BASE COUNT          183 a          131 c           67 g          227 t
ORIGIN      
        1 atttttaaat ttctgttata tacataaatg tcattatagt aatcaggaaa ctgttcatta
       61 aaacttgcca cttcaaaatc gtatccggct ttttcttccg ttaccctatc cgatgaaatt
      121 tcataaagtc cttgattttc aagataaaaa acatcattta aatcggtcaa attgacctct
      181 ttcatgccta ttgcaatctc atcgaaaagt ttatctattt ttgcactttc ttcaaaggtg
      241 ctgccacgat acaatgggta aatttttccc tcaaagttat tttctttcgg ataaacacga
      301 actcctgttt cttctaagga tatatccttt actctttctt tttctacaac agcatagtaa
      361 ttcccaacct taacggcaat tttatcttca ttcggtatct cagctatatt atcttctaac
      421 cttacctttt cagcctctat tttctccaaa aaatagtcaa cattgcttga atacagtaaa
      481 ctgtccgcat tgttatagac taccctatat tctccatcat tattttggaa aaaagtcagt
      541 cgaattaaat ccgaaatatt ttcatcatct tcaaacggat tatattcatc aagccttaga
      601 ccatcggt
//
LOCUS       DARYVE010000160          575 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.161, whole genome shotgun sequence.
ACCESSION   DARYVE010000160 DARYVE010000000
VERSION     DARYVE010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.161"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..>575)
                     /locus_tag="TVW25_002006"
     CDS             complement(<1..>575)
                     /locus_tag="TVW25_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1379581.1"
                     /translation="AGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLNSAKMDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT          159 a          148 c          110 g          158 t
ORIGIN      
        1 gcatacctaa aaaacctagc accgcaaaaa cgaccgctcg acgcgctgtt aatcccgtca
       61 cctgacgagg ttatcccgat cgaggcgtaa agcgcactac ctgtataatt ttttggcgtg
      121 gcattgctaa aatgcacaaa ggctgtgtgg gtaccgtctt tacgtacaag cgcattgtcc
      181 ttgttgttaa agttaatggt agcattgcta ttaaaatcca ttttagccga gtttaaatca
      241 atcatcatcg ctccgttgcg agctctgata actttaccct caagcaaact tgtaatcgta
      301 tgttcaattt tagccctgat aaagttagca tctaagccga caatgctgct agcgttaaga
      361 ttgatcactc taatcttagc agcgtcaatc gtaccaccaa tgatttgatc agctttgagc
      421 ttaataaact caccgagctt agccccaaat gccccattga cggtcgtatt accgtccaga
      481 gcaatacgct cgccagagat ccgcacgcca tagccattaa gatttatcgc tgagataatc
      541 tctttagcgc tcatcttagc gtcaatacca ccggc
//
LOCUS       DARYVE010000161          574 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.162, whole genome shotgun sequence.
ACCESSION   DARYVE010000161 DARYVE010000000
VERSION     DARYVE010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.162"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(<1..>574)
                     /locus_tag="TVW25_002007"
     CDS             complement(<1..>574)
                     /locus_tag="TVW25_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1379582.1"
                     /translation="PFISNIEKVFILILISIFLLASNIIPAWYTSILFMTACMIGNIA
                     EKQVILSGITSGAAWLVISGVIIGAAVKHTELDRLLARFFIPVCMGKYSKVLFGTILL
                     GVVLIFLMPSAMGRVVLLLPILNALSLELGYEKGSKEWEGIVMSGVLATYIPAFYVLP
                     SNVPNNVFTGAILSLYSINISYSRYFLLYFP"
BASE COUNT          215 a          113 c           83 g          163 t
ORIGIN      
        1 gggaagtaca agagaaagta tctgctatag gatatattta tggagtaaag acttaaaatt
       61 gctccagtaa aaacattatt tggaacattg gaaggtaata cataaaatgc aggtatatag
      121 gttgctaaaa cccctgacat aacaattcct tcccattcct tacttccttt ttcataacct
      181 aattctaaag atagggcatt tagaataggt aaaagcaaaa ctactctacc cattgctgat
      241 ggcatcaaaa aaattagtac cactcctagc aaaatcgtcc caaataacac tttagaatat
      301 ttccccatgc acaccggaat aaaaaatctc gcaagtaatc tatcaagttc agtatgcttt
      361 actgccgccc ctataataac acctgaaata acaagccatg ctgcacctga agttatccct
      421 gataagatga cttgcttctc agctatattc cctatcatac aagctgtcat aaataaaatg
      481 cttgtatacc atgcaggaat tatattgctt gccaaaagga agatagatat aagaatcaaa
      541 ataaaaactt tctctatatt tgaaataaat ggta
//
LOCUS       DARYVE010000162          562 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.163, whole genome shotgun sequence.
ACCESSION   DARYVE010000162 DARYVE010000000
VERSION     DARYVE010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.163"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..379
                     /locus_tag="TVW25_002008"
     CDS             <1..379
                     /locus_tag="TVW25_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379583.1"
                     /translation="GFRRGETYTISFSQTCELLKKVAITLTQANNKGVKLVLTPTKAK
                     MEAQTFNLSKDKEVISVYPLSYRAALTGDWYKSKQVDLNAAEVQNLALEMAYRDVVDS
                     NNASLVLDWSENPDVIFDGNGGS"
     gene            379..>562
                     /locus_tag="TVW25_002009"
     CDS             379..>562
                     /locus_tag="TVW25_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1379584.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGP"
BASE COUNT          176 a           99 c          140 g          147 t
ORIGIN      
        1 tggttttaga cgcggcgaga catacacgat tagctttagc cagacctgtg agttgctcaa
       61 aaaagtggct atcacgctga cgcaagctaa taataaggga gttaaactgg tactgacacc
      121 taccaaagct aagatggagg cgcagacctt taatctaagt aaagataagg aggtcatcag
      181 cgtctatcct ttgagctaca gagccgcttt aactggtgac tggtataaat ctaagcaagt
      241 tgacttaaat gcggcagagg tccaaaattt ggctctggag atggcttata gagacgtagt
      301 tgatagcaat aatgctagtt tagttttgga ttggtcagaa aatccagatg ttatttttga
      361 tggaaatgga ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg
      421 acaaaaaacg agtgggagtc tagtgacatc attttgccac aaggccagct cgtctatgag
      481 tctgacacag gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat
      541 caaggtgggc caccaggtcc cc
//
LOCUS       DARYVE010000163          499 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.164, whole genome shotgun sequence.
ACCESSION   DARYVE010000163 DARYVE010000000
VERSION     DARYVE010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.164"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(275..>499)
                     /locus_tag="TVW25_002010"
     CDS             complement(275..>499)
                     /locus_tag="TVW25_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1379585.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          120 a           91 c          117 g          171 t
ORIGIN      
        1 gaaattagcg catagaaaaa acgtatcagt tacgattata gtctagtttg tctttatgaa
       61 atatagataa cactgtacaa tccttttctt ttattgtacg actttataca aagaaaagcc
      121 cttggaaatt attttctaag gacttttttc aatttgagag gctggtgata gcctcttttt
      181 gaacttaggt catcttctta gggcaatgct gcctgaagag atgagaaaag ctgttactag
      241 ctcattgcct aaggggaaag gtgcaatggc tggtttagtt tttcttgcct tttaatgtta
      301 gcatgccggc gctagcgata acaccaaggg ctgcaagggt gaagaatggg tgatttgtct
      361 cccctgtagc tggtagtgtg cccttttgag ctgctggcgc catagctttt gctgttgatt
      421 tagaatctgc tttaggtgct gatggcttag catcttttcc atggtgaccc ttatgtccat
      481 gctcgccttg gccttggat
//
LOCUS       DARYVE010000164          451 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.165, whole genome shotgun sequence.
ACCESSION   DARYVE010000164 DARYVE010000000
VERSION     DARYVE010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.165"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(6..79)
                     /locus_tag="TVW25_002011"
     tRNA            complement(6..79)
                     /locus_tag="TVW25_002011"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43..45),aa:Ile,seq:cat)
     gene            complement(100..173)
                     /locus_tag="TVW25_002012"
     tRNA            complement(100..173)
                     /locus_tag="TVW25_002012"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(137..139),aa:Met,seq:cat)
     gene            complement(184..257)
                     /locus_tag="TVW25_002013"
     tRNA            complement(184..257)
                     /locus_tag="TVW25_002013"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(221..223),aa:Pro,seq:tgg)
     gene            complement(264..337)
                     /locus_tag="TVW25_002014"
     tRNA            complement(264..337)
                     /locus_tag="TVW25_002014"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(301..303),aa:Arg,seq:acg)
     gene            complement(352..436)
                     /locus_tag="TVW25_002015"
     tRNA            complement(352..436)
                     /locus_tag="TVW25_002015"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(400..402),aa:Leu,seq:taa)
BASE COUNT          121 a          135 c          103 g           92 t
ORIGIN      
        1 cattatggac cttgtaggac tcgaacctac gaccgctcgg ttatgagccg agtgctctaa
       61 ccagttgagc taaaggtcca aaacaatcca aaaacaaaat agcggcgaag gggatcgaac
      121 ccccgacctc ccgggtatga accggacgct ctagccagct gagctacacc gccatcaaac
      181 taatcgggaa gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca
      241 agctgagcta cttcccgtaa ctatgcaccc tagaggagtc gaacctctaa ccgcctgatt
      301 cgtagtcagg tactctatcc agttgagcta agggtgcttt tccttatgct atgccgagga
      361 ccggaatcga accggtacga tgttaaccat cgcaggattt taagtcctgt gcgtctgcca
      421 gttccgccac cccggctccc caaaagcgaa c
//
LOCUS       DARYVE010000165          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.166, whole genome shotgun sequence.
ACCESSION   DARYVE010000165 DARYVE010000000
VERSION     DARYVE010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.166"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(68..139)
                     /locus_tag="TVW25_002016"
     tRNA            complement(68..139)
                     /locus_tag="TVW25_002016"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYVE010000166          388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.167, whole genome shotgun sequence.
ACCESSION   DARYVE010000166 DARYVE010000000
VERSION     DARYVE010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.167"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            complement(55..127)
                     /locus_tag="TVW25_002017"
     tRNA            complement(55..127)
                     /locus_tag="TVW25_002017"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92..94),aa:Thr,seq:tgt)
     gene            complement(135..216)
                     /locus_tag="TVW25_002018"
     tRNA            complement(135..216)
                     /locus_tag="TVW25_002018"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Leu,seq:tag)
     gene            complement(222..294)
                     /locus_tag="TVW25_002019"
     tRNA            complement(222..294)
                     /locus_tag="TVW25_002019"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(259..261),aa:Lys,seq:ttt)
     gene            complement(298..370)
                     /locus_tag="TVW25_002020"
     tRNA            complement(298..370)
                     /locus_tag="TVW25_002020"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(335..337),aa:Asp,seq:gtc)
BASE COUNT           98 a          119 c           85 g           86 t
ORIGIN      
        1 cccaccttgg caaggtggtg ttctaccact gaactacgtt cgcaactcta tcaatgccgg
       61 ctacatgact tgaacacgcg accctctgat tacaaatcag atgctctacc aactgagcta
      121 agccggccta tctatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      181 taaatctggt gcgtctgcca attccgccaa acccgccttt atgacccgta ctgggctcga
      241 accagtgacc ctttgattaa aagtcaaatg ctctaccaac tgagctaacg agtcctacgg
      301 tcccgacggg aatcgaaccc gcgatcttcg ccgtgacagg gcgacgtgat aaccgctaca
      361 ctacgggacc tattcataac ttatggga
//
LOCUS       DARYVE010000167          383 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.168, whole genome shotgun sequence.
ACCESSION   DARYVE010000167 DARYVE010000000
VERSION     DARYVE010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.168"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            257..>383
                     /locus_tag="TVW25_002021"
     CDS             257..>383
                     /locus_tag="TVW25_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1379586.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSI"
BASE COUNT          164 a           50 c           74 g           95 t
ORIGIN      
        1 atgactactc aaaattaaga taaaaatccc aaaaatgaaa agcatagtaa agatatcatc
       61 acaaagagaa gcaagtgctc atcaacagac agaagtataa gaggaaaatg cagatataga
      121 ggagtcgtac atgtaaaaaa gtaagggcta gacctataag gaaacgattt tatggaaagt
      181 atacttgcca ttttctctaa aaaacattat actatatgta aagttagctt gtcattgttg
      241 caggaggtca ttaaatgtga aaaatagact tgaggaaatc agaaaagaaa atggaataac
      301 acaggaagag ttagcatcta ttcttgaagt atcaaggcag acaattggtt ctttagaaaa
      361 cggaaggtat aatccttcca tta
//
LOCUS       DARYVE010000168          369 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.169, whole genome shotgun sequence.
ACCESSION   DARYVE010000168 DARYVE010000000
VERSION     DARYVE010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.169"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..>369
                     /locus_tag="TVW25_002022"
     CDS             <1..>369
                     /locus_tag="TVW25_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL1379587.1"
                     /translation="INIGKTEVIIKAFNEMGRKNLDTDMRMLFSMTVGYASGRLTLSS
                     PLGPVLWEQSPNVPKIDLIPRFLDGNDNEGCSKPWLSILYEGDTYYKSYVYRNIWVEA
                     IMDDLKEFVFEDKSKKQSNSM"
BASE COUNT          134 a           39 c           77 g          119 t
ORIGIN      
        1 ataaatattg gtaaaacaga ggttattata aaggcattta atgaaatggg taggaaaaat
       61 ttagatacgg atatgcgtat gcttttttct atgactgtgg gatatgcgtc tggtaggcta
      121 actttatcaa gtcctcttgg accagtttta tgggaacaat cacctaatgt acctaaaata
      181 gatcttatac caagattttt agacggcaat gataatgaag gatgtagtaa accttggtta
      241 tcaattcttt atgagggaga tacatattat aaatcatatg tatatagaaa tatttgggtt
      301 gaagcaataa tggacgattt gaaagagttc gtttttgagg acaaaagtaa aaaacaaagt
      361 aatagtatg
//
LOCUS       DARYVE010000169          341 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.170, whole genome shotgun sequence.
ACCESSION   DARYVE010000169 DARYVE010000000
VERSION     DARYVE010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.170"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            <1..323
                     /locus_tag="TVW25_002023"
     CDS             <1..323
                     /locus_tag="TVW25_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1379588.1"
                     /translation="STIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVVFINVST
                     WRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGYLDGLET
                     HDYY"
BASE COUNT          119 a           62 c           74 g           86 t
ORIGIN      
        1 ttagcacaat cgcagtcgaa aaaaactcgg ttatgggtcc aaatcaacaa tccatgctta
       61 aaatcggcat tgtaactggt atcatcttag gacgattgat agctgataat gtcgtattta
      121 tcaatgtctc aacttggcga aagcactgga agtttagcta caaagaccgc tcaaaaaaag
      181 caatgaaagc acagtcaaag gctaaggctg ctgaaaactt tggcaaaata gtcaaagatg
      241 atgaggcaga tgccgtcttg attggtgcat actatgtcaa tcaaggctat cttgatggat
      301 tggagacaca tgactactac taaaaaacac gttgtgagga t
//
LOCUS       DARYVE010000170          324 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.denovo.171, whole genome shotgun sequence.
ACCESSION   DARYVE010000170 DARYVE010000000
VERSION     DARYVE010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.denovo.171"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            96..>324
                     /locus_tag="TVW25_002024"
     CDS             96..>324
                     /locus_tag="TVW25_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002948623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein FlaR"
                     /protein_id="HEL1379589.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERM"
BASE COUNT          111 a           46 c           60 g          107 t
ORIGIN      
        1 ggcttttttg cttgtctaaa gaggatttgt ccccaaaata tattctttat gctataatat
       61 aagtcaaagt acagcattga caaaggagac aaagattgaa aattgtaata attggctata
      121 gtggttctgg aaagtcgact ttagcaaatg ttttaggtca acactacaat tgtgctgtac
      181 ttcatttaga caaaattcat tttgcatcaa actggcaaga gcgaacagtt agtcaaatgg
      241 tctctgatat atcaacattt atgtcacaaa aacattggat tattgaaggt aattattcaa
      301 gctgtcttta tgaagagcgt atga
//
LOCUS       DARYVE010000171         1835 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611889-rid16720523.guided.116, whole genome shotgun sequence.
ACCESSION   DARYVE010000171 DARYVE010000000
VERSION     DARYVE010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611889
            Sequence Read Archive: SRR18311158
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574887.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:06:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,984
            Genes (coding)                    :: 1,905
            CDSs (with protein)               :: 1,905
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 33 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 26 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1835
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611889-rid16720523.guided.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: NY"
                     /collection_date="2019-05-08"
                     /collected_by="Cornell Animal Health Diagnostic Center,
                     Ithaca, NY"
     gene            40..1761
                     /locus_tag="TVW25_002025"
     CDS             40..1761
                     /locus_tag="TVW25_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1379590.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
BASE COUNT          506 a          317 c          447 g          565 t
ORIGIN      
        1 gacagcttga aataggttag ttcagaaatg gaggatatga tgctgacctt aattgttcaa
       61 catattaagc aaaagaaatg gatttatatc cttattgcaa tgactttagt gatatatgat
      121 gcctcacttg tgataccaac aagggttatt caagacttgg ttgatttgat gtcaaggcat
      181 cagctaagct caggggcatt ggtgaggcat gttatcattc ttttggctac ggcagtagtg
      241 tcttatgggg ttgcttattt gtggcatctt catttatttc aggaggcagt tcattttaag
      301 tttgatattc agcagcgtgc ctttcgaaag cttgttttta tgagaacgcc tttttatgag
      361 aaatttcgct caggtgacat gatcacgcgt ttttcaacag atgtcgaagc acttatggac
      421 cttatcggct atggcttgat gattatccta tatgctggtg gtatgattgc ttttattatt
      481 ccgaccatgt ttttgatttc ttggaaaatg accttgatag gaatagtacc gattttgctt
      541 atgatggtga tgatctatgg tgtgacgaaa aagcaagagc atttggttga agaggcgcgt
      601 gaggcgattt caagccttag tgatgaggta ctagaaaccg ttgagggcat tagagtgatg
      661 cgtgcttaca gtaaaaaaga ttatttggca cttcattttg ctcaaaagac tcagaatttg
      721 gcagataaat ggaatcaggt ggccaagtat cgtgccttgt actttcctct ttacagcgtc
      781 atgattgcca ttagtacagt aatcatttta atggtaggcc tacagctcat agcaagctca
      841 gaggtaacac ttggtcaagt cattgcgctg cagctttatc tggtgtcttt ggtggagccc
      901 tttggcatgc tgtcagactt tattttggtt tatcagacag gaaagacctc ttttggtaag
      961 attaatgaac tcatcgaaac aagtgatgat atggagcctg atggccagct tgagttagag
     1021 agctttgatc agattgcttt tatagactat agctttacct atgccaatag ttctaggcct
     1081 agcttagaaa agatcaattt aaccctgaaa aagggacaaa ccttagggat tgttggtaaa
     1141 acaggctctg gtaaaacaac ccttgtcagg cagtttttga gacaataccc tcttgggcag
     1201 gggcagctga tgattaatca tcgtagtgtc ttggattata agcgtcaatc acttgagcgt
     1261 caaattggct atgtgccaca ggagcatatc ctgttttcaa aaacggttgc tcaaaacatt
     1321 gcgatgggga aaaaggcagc tacaactgag gaaatcttgg aggcgattga aactgcggcc
     1381 tttacgcgtg atgttcaagg aatggcaaag ggcttggata ctgagattgg agagcgtggt
     1441 ctgtctattt caggaggtca aaagcagcgt atttcgattg ccagagcctt tttgtcccag
     1501 ccagatttgc tgattttaga tgattccctg tcggcagttg atgctagaac agagactgat
     1561 attattcgac acattcaaga cgaaagaaag ggaaagacaa cacttattgt tagccatcgc
     1621 ttgtctgcga ttcagcatgc cgattgggtt attgttctgg atcaggggca gatagtagag
     1681 gaaggtcagc cccaacaact tttagctcag aagggctggt attatgaaca gtaccagcgt
     1741 cagcaggctc aggaggttta agatgaccct atttataaaa ttaataaaag aaattaaagc
     1801 tgtgaccttg gctttttccc tggcaatagg ctttt
//
